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Conserved domains on  [gi|2024339653|ref|XP_040506563|]
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ELKS/Rab6-interacting/CAST family member 1 isoform X2 [Gallus gallus]

Protein Classification

Cast and RBD-FIP domain-containing protein( domain architecture ID 12103785)

Cast and RBD-FIP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 154-989 0e+00

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


:

Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 1027.46  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQ 233
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  234 DELRIQRDLNQLFQQD---SSSRTSEPFVA-ELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESI 309
Cdd:pfam10174   81 DELRAQRDLNQLLQQDfttSPVDGEDKFSTpELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  310 KKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDS 389
Cdd:pfam10174  161 KKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDT 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  390 KISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFS 469
Cdd:pfam10174  241 KISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNS 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  470 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQ 549
Cdd:pfam10174  321 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  550 KKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDL 629
Cdd:pfam10174  401 KKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  630 KEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRM 709
Cdd:pfam10174  481 KEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRI 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  710 QQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERkhasrklhppyqvsvpapqhvggfvwdflgnLT 789
Cdd:pfam10174  561 RLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELES-------------------------------LT 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  790 SRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQlqdnlrkkddrieeleealresvqitaeremvlaq 869
Cdd:pfam10174  610 LRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQ----------------------------------- 654

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  870 eesarinaeKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 949
Cdd:pfam10174  655 ---------LQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAAISEKDANI 725

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 2024339653  950 ALLELSSS-KKKTQDEVAALKREKDRLVQQLKQQTQNRMKL 989
Cdd:pfam10174  726 ALLELSSSkKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 766
RBD-FIP super family cl09694
FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of ...
 1076-1116 3.85e-07

FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of Rab11-interacting proteins (FIPs). The Rab proteins constitute the largest family of small GTPases (>60 members in mammals). Among them Rab11 is a well characterized regulator of endocytic and recycling pathways. Rab11 associates with a broad range of post-Golgi organelles, including recycling endosomes.


The actual alignment was detected with superfamily member pfam09457:

Pssm-ID: 462805 [Multi-domain]  Cd Length: 41  Bit Score: 47.33  E-value: 3.85e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 2024339653 1076 TQEQLRDELEKGEKESAELQEFANAILQQIADHCPDILEQV 1116
Cdd:pfam09457    1 SRDELQDALQKQEEENRRLEDYIDNILLRIMEHNPSILEVP 41
PRK11091 super family cl35988
aerobic respiration control sensor protein ArcB; Provisional
 818-880 9.12e-03

aerobic respiration control sensor protein ArcB; Provisional


The actual alignment was detected with superfamily member PRK11091:

Pssm-ID: 236842 [Multi-domain]  Cd Length: 779  Bit Score: 40.31  E-value: 9.12e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  818 LEEARRREDNLNdssQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQ 880
Cdd:PRK11091    94 LEEMRERDLELN---VQLKDNIAQLNQEIAEREKAEEARQEAFEQLKNEIKEREETQIELEQQ 153
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 154-989 0e+00

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 1027.46  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQ 233
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  234 DELRIQRDLNQLFQQD---SSSRTSEPFVA-ELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESI 309
Cdd:pfam10174   81 DELRAQRDLNQLLQQDfttSPVDGEDKFSTpELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  310 KKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDS 389
Cdd:pfam10174  161 KKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDT 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  390 KISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFS 469
Cdd:pfam10174  241 KISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNS 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  470 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQ 549
Cdd:pfam10174  321 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  550 KKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDL 629
Cdd:pfam10174  401 KKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  630 KEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRM 709
Cdd:pfam10174  481 KEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRI 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  710 QQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERkhasrklhppyqvsvpapqhvggfvwdflgnLT 789
Cdd:pfam10174  561 RLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELES-------------------------------LT 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  790 SRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQlqdnlrkkddrieeleealresvqitaeremvlaq 869
Cdd:pfam10174  610 LRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQ----------------------------------- 654

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  870 eesarinaeKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 949
Cdd:pfam10174  655 ---------LQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAAISEKDANI 725

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 2024339653  950 ALLELSSS-KKKTQDEVAALKREKDRLVQQLKQQTQNRMKL 989
Cdd:pfam10174  726 ALLELSSSkKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 766
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 442-997 5.81e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.63  E-value: 5.81e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  442 QVKQELSRKDTELLALqtKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIA 521
Cdd:COG1196    217 ELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  522 EEkgtqageihdlkdmLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTI 601
Cdd:COG1196    295 AE--------------LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  602 ERLKEQRDRDEREKQEEIDTYKKDIKDLKEkvgiLQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEE 681
Cdd:COG1196    361 AEAEEALLEAEAELAEAEEELEELAEELLE----ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  682 CLKMETQLKKAHEATLEARASPE-LSDRMQQLEREVTRYREESSKAQAEVDRL---LEILKEMENEKNDKDKKIAELERK 757
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEEEEaLLELLAELLEEAALLEAALAELLEELAEAaarLLLLLEAEADYEGFLEGVKAALLL 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  758 HASRKLHPPYQVSVPAPQHVGGFVWDFLGNLTSRQV--KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL 835
Cdd:COG1196    517 AGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVveDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  836 QDNLRK-KDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELmmamEKVKQELESMKAKLSSTQQSLAEKET 914
Cdd:COG1196    597 IGAAVDlVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL----REVTLEGEGGSAGGSLTGGSRRELLA 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  915 HLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNY 994
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752


                   ...
gi 2024339653  995 EDD 997
Cdd:COG1196    753 LEE 755
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 458-1108 1.60e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 1.60e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  458 QTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDM 537
Cdd:TIGR02168  224 ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  538 LEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQrdrdEREKQE 617
Cdd:TIGR02168  304 KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR----LEELEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  618 EIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATL 697
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  698 EARASpELSDRMQQLEREVTRYREESSKAQAEvdrlLEILKEMENEKNDKDKKIAELErKHASRK--LHPPY--QVSVP- 772
Cdd:TIGR02168  460 EEALE-ELREELEEAEQALDAAERELAQLQAR----LDSLERLQENLEGFSEGVKALL-KNQSGLsgILGVLseLISVDe 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  773 ----APQHVGGfvwDFLGNLTSRQVKDQNKKVANLKHKEQ------VEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKK 842
Cdd:TIGR02168  534 gyeaAIEAALG---GRLQAVVVENLNAAKKAIAFLKQNELgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  843 DDRI--------------EELEEALRESVQITAEREMVLAQEESARI---------NAEKQVEELMMAMEKVKQELESMK 899
Cdd:TIGR02168  611 DPKLrkalsyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPggvitggsaKTNSSILERRREIEELEEKIEELE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  900 AKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEallaaisekdaniaLLELSSSKKKTQDEVAALKREKDRLVQQL 979
Cdd:TIGR02168  691 EKIAELEKALAELRKELEELEEELEQLRKELEELSRQ--------------ISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  980 KQQTQNRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQIIQpllELDQNRSKLKLYIGHLTALCHDRDPLILRgltppaSY 1059
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---ELKALREALDELRAELTLLNEEAANLRER------LE 827

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024339653 1060 HLDDDRAAWEKELQKMTQ--EQLRDELEKGEKESAELQEFANAILQQIADH 1108
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEqiEELSEDIESLAAEIEELEELIEELESELEAL 878
PTZ00121 PTZ00121
MAEBL; Provisional
 226-946 1.05e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.41  E-value: 1.05e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  226 QMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNAR 305
Cdd:PTZ00121  1031 ELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGK 1110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  306 DESIKKLLEMLQSKGLSAKATE-EDHERTRRLAEAEMHVHhlESLLEQKEKENNMLREEIHRRfenAPDSAKTKALQTVI 384
Cdd:PTZ00121  1111 AEEARKAEEAKKKAEDARKAEEaRKAEDARKAEEARKAED--AKRVEIARKAEDARKAEEARK---AEDAKKAEAARKAE 1185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  385 EMKDSKISSMERGLRDLE-----EEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQT 459
Cdd:PTZ00121  1186 EVRKAEELRKAEDARKAEaarkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF 1265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  460 KLETLTNQFSDSKQHIEVLK--ESLTAKEQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQEIAEEKGTQAGEIhdlK 535
Cdd:PTZ00121  1266 ARRQAAIKAEEARKADELKKaeEKKKADEAKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEAKKKADAAKKKAEEA---K 1342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  536 DMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREK 615
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  616 QEEIDTYKKDIKDLKEKVG-ILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIA-----LEQKKEECLKMETQL 689
Cdd:PTZ00121  1423 AKKKAEEKKKADEAKKKAEeAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAkkadeAKKKAEEAKKKADEA 1502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  690 KKAHEATL---EARASPELSDRMQQLEREVTRYREESSKAQ----AEVDRLLEILKEMENEKNDKDKKIAELERKHASRK 762
Cdd:PTZ00121  1503 KKAAEAKKkadEAKKAEEAKKADEAKKAEEAKKADEAKKAEekkkADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK 1582

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  763 LHPPYQVSVPAPQHVGGFVWDFLGNLTS---------------RQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDN 827
Cdd:PTZ00121  1583 AEEAKKAEEARIEEVMKLYEEEKKMKAEeakkaeeakikaeelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  828 LNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAE---------KQVEELMMAMEKVKQELESM 898
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEekkkaeelkKAEEENKIKAEEAKKEAEED 1742

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 2024339653  899 KAKLSSTQQSLAEKEThLTNLRAERRKHLEEVLEMKQEALLAAISEKD 946
Cdd:PTZ00121  1743 KKKAEEAKKDEEEKKK-IAHLKKEEEKKAEEIRKEKEAVIEEELDEED 1789
RBD-FIP pfam09457
FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of ...
 1076-1116 3.85e-07

FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of Rab11-interacting proteins (FIPs). The Rab proteins constitute the largest family of small GTPases (>60 members in mammals). Among them Rab11 is a well characterized regulator of endocytic and recycling pathways. Rab11 associates with a broad range of post-Golgi organelles, including recycling endosomes.


Pssm-ID: 462805 [Multi-domain]  Cd Length: 41  Bit Score: 47.33  E-value: 3.85e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 2024339653 1076 TQEQLRDELEKGEKESAELQEFANAILQQIADHCPDILEQV 1116
Cdd:pfam09457    1 SRDELQDALQKQEEENRRLEDYIDNILLRIMEHNPSILEVP 41
Mrs2_Mfm1p-like cd12823
Saccharomyces cerevisiae inner mitochondrial membrane Mg2+ transporters Mfm1p and Mrs2p-like ...
 451-563 3.29e-03

Saccharomyces cerevisiae inner mitochondrial membrane Mg2+ transporters Mfm1p and Mrs2p-like family; A eukaryotic subfamily belonging to the Escherichia coli CorA-Salmonella typhimurium ZntB_like family (EcCorA_ZntB-like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This functionally diverse subfamily includes the inner mitochondrial membrane Mg2+ transporters Saccharomyces cerevisiae Mfm1p/Lpe10p, Mrs2p, and human MRS2/ MRS2L. It also includes a family of Arabidopsis thaliana proteins (AtMGTs) some of which are localized to distinct tissues, and not all of which can transport Mg2+. Structures of the intracellular domain of two EcCorA_ZntB-like family transporters: Vibrio parahaemolyticus and Salmonella typhimurium ZntB form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA, and Mrs2p. Natural variants such as GVN and GIN, as in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.


Pssm-ID: 213357  Cd Length: 323  Bit Score: 41.08  E-value: 3.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  451 DTELLALQTK----LETLTNQFSDSK-QHIEVLKESLTAKEQRAAILQTEVDALrlrLEEKETM--LNKKTKQIQEIAEE 523
Cdd:cd12823    127 EAELKRLEPEalplLDELTDKISTSNlERLLPLKRRLVELETRVQKVRDALEEL---LDDDEDMadMYLTDKAAGPERLE 203

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 2024339653  524 KGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKE 563
Cdd:cd12823    204 SSRKEDDHEEVEMLLEAYLQQVDELLNKLEELREYIDDTE 243
PRK11091 PRK11091
aerobic respiration control sensor protein ArcB; Provisional
 818-880 9.12e-03

aerobic respiration control sensor protein ArcB; Provisional


Pssm-ID: 236842 [Multi-domain]  Cd Length: 779  Bit Score: 40.31  E-value: 9.12e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  818 LEEARRREDNLNdssQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQ 880
Cdd:PRK11091    94 LEEMRERDLELN---VQLKDNIAQLNQEIAEREKAEEARQEAFEQLKNEIKEREETQIELEQQ 153
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 154-989 0e+00

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 1027.46  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQ 233
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  234 DELRIQRDLNQLFQQD---SSSRTSEPFVA-ELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESI 309
Cdd:pfam10174   81 DELRAQRDLNQLLQQDfttSPVDGEDKFSTpELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  310 KKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDS 389
Cdd:pfam10174  161 KKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDT 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  390 KISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFS 469
Cdd:pfam10174  241 KISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNS 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  470 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQ 549
Cdd:pfam10174  321 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  550 KKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDL 629
Cdd:pfam10174  401 KKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  630 KEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRM 709
Cdd:pfam10174  481 KEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRI 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  710 QQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERkhasrklhppyqvsvpapqhvggfvwdflgnLT 789
Cdd:pfam10174  561 RLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELES-------------------------------LT 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  790 SRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQlqdnlrkkddrieeleealresvqitaeremvlaq 869
Cdd:pfam10174  610 LRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQ----------------------------------- 654

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  870 eesarinaeKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 949
Cdd:pfam10174  655 ---------LQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAAISEKDANI 725

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 2024339653  950 ALLELSSS-KKKTQDEVAALKREKDRLVQQLKQQTQNRMKL 989
Cdd:pfam10174  726 ALLELSSSkKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 766
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 442-997 5.81e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.63  E-value: 5.81e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  442 QVKQELSRKDTELLALqtKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIA 521
Cdd:COG1196    217 ELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  522 EEkgtqageihdlkdmLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTI 601
Cdd:COG1196    295 AE--------------LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  602 ERLKEQRDRDEREKQEEIDTYKKDIKDLKEkvgiLQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEE 681
Cdd:COG1196    361 AEAEEALLEAEAELAEAEEELEELAEELLE----ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  682 CLKMETQLKKAHEATLEARASPE-LSDRMQQLEREVTRYREESSKAQAEVDRL---LEILKEMENEKNDKDKKIAELERK 757
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEEEEaLLELLAELLEEAALLEAALAELLEELAEAaarLLLLLEAEADYEGFLEGVKAALLL 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  758 HASRKLHPPYQVSVPAPQHVGGFVWDFLGNLTSRQV--KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL 835
Cdd:COG1196    517 AGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVveDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  836 QDNLRK-KDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELmmamEKVKQELESMKAKLSSTQQSLAEKET 914
Cdd:COG1196    597 IGAAVDlVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL----REVTLEGEGGSAGGSLTGGSRRELLA 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  915 HLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNY 994
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752


                   ...
gi 2024339653  995 EDD 997
Cdd:COG1196    753 LEE 755
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 458-1108 1.60e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 1.60e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  458 QTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDM 537
Cdd:TIGR02168  224 ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  538 LEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQrdrdEREKQE 617
Cdd:TIGR02168  304 KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR----LEELEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  618 EIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATL 697
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  698 EARASpELSDRMQQLEREVTRYREESSKAQAEvdrlLEILKEMENEKNDKDKKIAELErKHASRK--LHPPY--QVSVP- 772
Cdd:TIGR02168  460 EEALE-ELREELEEAEQALDAAERELAQLQAR----LDSLERLQENLEGFSEGVKALL-KNQSGLsgILGVLseLISVDe 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  773 ----APQHVGGfvwDFLGNLTSRQVKDQNKKVANLKHKEQ------VEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKK 842
Cdd:TIGR02168  534 gyeaAIEAALG---GRLQAVVVENLNAAKKAIAFLKQNELgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  843 DDRI--------------EELEEALRESVQITAEREMVLAQEESARI---------NAEKQVEELMMAMEKVKQELESMK 899
Cdd:TIGR02168  611 DPKLrkalsyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPggvitggsaKTNSSILERRREIEELEEKIEELE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  900 AKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEallaaisekdaniaLLELSSSKKKTQDEVAALKREKDRLVQQL 979
Cdd:TIGR02168  691 EKIAELEKALAELRKELEELEEELEQLRKELEELSRQ--------------ISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  980 KQQTQNRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQIIQpllELDQNRSKLKLYIGHLTALCHDRDPLILRgltppaSY 1059
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---ELKALREALDELRAELTLLNEEAANLRER------LE 827

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024339653 1060 HLDDDRAAWEKELQKMTQ--EQLRDELEKGEKESAELQEFANAILQQIADH 1108
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEqiEELSEDIESLAAEIEELEELIEELESELEAL 878
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 399-981 4.77e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.00  E-value: 4.77e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  399 RDLEEEIQMLKSNGALSteEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVL 478
Cdd:COG1196    216 RELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  479 KESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQ 558
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  559 LRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQG 638
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  639 DLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQkkeecLKMETQLKKAHEATLEARASPELSDRMQQLEREVTR 718
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR-----LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  719 YREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKhasrklhppyqvsvpapQHVGGFVWDFLGNLTSRQVKDQNK 798
Cdd:COG1196    529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLK-----------------AAKAGRATFLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  799 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAE 878
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  879 KQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAA----ISEKDANIALLEL 954
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEReellEELLEEEELLEEE 751

                          570       580
                   ....*....|....*....|....*..
gi 2024339653  955 SSSKKKTQDEVAALKREKDRLVQQLKQ 981
Cdd:COG1196    752 ALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 302-989 1.68e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 1.68e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  302 LNARDESIKKLLEmlQSKGLSaKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEihrrfenAPDSAKTKALQ 381
Cdd:TIGR02168  150 IEAKPEERRAIFE--EAAGIS-KYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQ-------AEKAERYKELK 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  382 TVIEMKDSKISSMErgLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRShskfmknKIGQVKQELSRKDTELLALQTKL 461
Cdd:TIGR02168  220 AELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEE-------KLEELRLEVSELEEEIEELQKEL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  462 ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEI---------- 531
Cdd:TIGR02168  291 YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELeeleaeleel 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  532 ----HDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTA----------------LTTLE 591
Cdd:TIGR02168  371 esrlEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKleeaelkelqaeleelEEELE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  592 EALAEKERTIERLKEQRDRdEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKES---SLLDLKEHASSLA------SSGL 662
Cdd:TIGR02168  451 ELQEELERLEEALEELREE-LEEAEQALDAAERELAQLQARLDSLERLQENLEGfseGVKALLKNQSGLSgilgvlSELI 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  663 KKDSRLKT-LEIALEqkkEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQ--AEVDRLLEILKE 739
Cdd:TIGR02168  530 SVDEGYEAaIEAALG---GRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREilKNIEGFLGVAKD 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  740 MENEKNDKDKKIA----------ELERKHASRKLHPPYQVSVPAPQHVGGFVWDFLGNLTSRQVKDQNKKVANLKHKEQV 809
Cdd:TIGR02168  607 LVKFDPKLRKALSyllggvlvvdDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKI 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  810 EKKKSAqmLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALresvqitAEREMVLAQEESARINAEKQVEELMMAME 889
Cdd:TIGR02168  687 EELEEK--IAELEKALAELRKELEELEEELEQLRKELEELSRQI-------SALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  890 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALK 969
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          730       740
                   ....*....|....*....|
gi 2024339653  970 REKDRLVQQLKQQTQNRMKL 989
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESL 857
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 203-998 4.49e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 4.49e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  203 DEASKITIWKEQYRVLQEENQHMQMTIQALQDELR-IQRDLNQLFQQdsssrtsepfvAELTEEnFQRLHTEHERQAKEL 281
Cdd:TIGR02168  162 EEAAGISKYKERRKETERKLERTRENLDRLEDILNeLERQLKSLERQ-----------AEKAER-YKELKAELRELELAL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  282 FLLRktleemelrIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTR-RLAEAEMHVHHLES-LLEQKEKENNM 359
Cdd:TIGR02168  230 LVLR---------LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlEVSELEEEIEELQKeLYALANEISRL 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  360 LREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKsngalstEEREEEMKQMEVYRSHSKFMKNK 439
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK-------EELESLEAELEELEAELEELESR 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  440 IGQVKQELSRKDTELLALQTKLETLTNQfsdskqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKEtmlnkktkqIQE 519
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNE-------IERLEARLERLEDRRERLQQEIEELLKKLEEAE---------LKE 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  520 IAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKER 599
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  600 ---TIERLKEQRDRDEREKQ---------------EEIDTYKKDIKDLKEK----------VGILQGDLTEKESSLLDLK 651
Cdd:TIGR02168  518 lsgILGVLSELISVDEGYEAaieaalggrlqavvvENLNAAKKAIAFLKQNelgrvtflplDSIKGTEIQGNDREILKNI 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  652 EHASSLASSGLKKDSRLK--------------TLEIALEQKKEECLKM-----ETQLKKAHEATLEARASPELSD----- 707
Cdd:TIGR02168  598 EGFLGVAKDLVKFDPKLRkalsyllggvlvvdDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGSAKTNSSIlerrr 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  708 RMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKlhppyqvsvpapqhvggfvwdflgn 787
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR------------------------- 732

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  788 ltsrqvkdqnkkvanlkhkeqvekkksaQMLEEARRREDNLNDSSQQLQDNLrkkddriEELEEALRESVQITAEREMVL 867
Cdd:TIGR02168  733 ----------------------------KDLARLEAEVEQLEERIAQLSKEL-------TELEAEIEELEERLEEAEEEL 777

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  868 AQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDA 947
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024339653  948 NIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDH 998
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES 908
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 323-976 9.60e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 9.60e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  323 AKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLRE-----EIHRRFENAPDSAKTKALQTVIEMKDSKISSMERG 397
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqallKEKREYEGYELLKEKEALERQKEAIERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  398 LRDLEEEIQML-KSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 476
Cdd:TIGR02169  253 LEKLTEEISELeKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEID 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  477 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQ 556
Cdd:TIGR02169  333 KLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  557 EQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE---KQEEIDTYKKDIKDLKEKV 633
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydLKEEYDRVEKELSKLQREL 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  634 GILQGDLTEKESSLLDLK-------------------------EHASSLASSGlkkDSRLKTLEIALEQKKEECLK---- 684
Cdd:TIGR02169  493 AEAEAQARASEERVRGGRaveevlkasiqgvhgtvaqlgsvgeRYATAIEVAA---GNRLNNVVVEDDAVAKEAIEllkr 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  685 -----------------------------------------------------------MET---QLKKAHEATLEAR-- 700
Cdd:TIGR02169  570 rkagratflplnkmrderrdlsilsedgvigfavdlvefdpkyepafkyvfgdtlvvedIEAarrLMGKYRMVTLEGElf 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  701 -------------------------ASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELE 755
Cdd:TIGR02169  650 eksgamtggsraprggilfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  756 RKHASRKlhppyqvsvpapqhvggfvwDFLGNLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR------EDNLN 829
Cdd:TIGR02169  730 QEEEKLK--------------------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEealndlEARLS 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  830 DSS-QQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQS 908
Cdd:TIGR02169  790 HSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE 869

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024339653  909 LAEK-------ETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLV 976
Cdd:TIGR02169  870 LEELeaalrdlESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
PTZ00121 PTZ00121
MAEBL; Provisional
 226-946 1.05e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.41  E-value: 1.05e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  226 QMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNAR 305
Cdd:PTZ00121  1031 ELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGK 1110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  306 DESIKKLLEMLQSKGLSAKATE-EDHERTRRLAEAEMHVHhlESLLEQKEKENNMLREEIHRRfenAPDSAKTKALQTVI 384
Cdd:PTZ00121  1111 AEEARKAEEAKKKAEDARKAEEaRKAEDARKAEEARKAED--AKRVEIARKAEDARKAEEARK---AEDAKKAEAARKAE 1185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  385 EMKDSKISSMERGLRDLE-----EEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQT 459
Cdd:PTZ00121  1186 EVRKAEELRKAEDARKAEaarkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF 1265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  460 KLETLTNQFSDSKQHIEVLK--ESLTAKEQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQEIAEEKGTQAGEIhdlK 535
Cdd:PTZ00121  1266 ARRQAAIKAEEARKADELKKaeEKKKADEAKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEAKKKADAAKKKAEEA---K 1342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  536 DMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREK 615
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  616 QEEIDTYKKDIKDLKEKVG-ILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIA-----LEQKKEECLKMETQL 689
Cdd:PTZ00121  1423 AKKKAEEKKKADEAKKKAEeAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAkkadeAKKKAEEAKKKADEA 1502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  690 KKAHEATL---EARASPELSDRMQQLEREVTRYREESSKAQ----AEVDRLLEILKEMENEKNDKDKKIAELERKHASRK 762
Cdd:PTZ00121  1503 KKAAEAKKkadEAKKAEEAKKADEAKKAEEAKKADEAKKAEekkkADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK 1582

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  763 LHPPYQVSVPAPQHVGGFVWDFLGNLTS---------------RQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDN 827
Cdd:PTZ00121  1583 AEEAKKAEEARIEEVMKLYEEEKKMKAEeakkaeeakikaeelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  828 LNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAE---------KQVEELMMAMEKVKQELESM 898
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEekkkaeelkKAEEENKIKAEEAKKEAEED 1742

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 2024339653  899 KAKLSSTQQSLAEKEThLTNLRAERRKHLEEVLEMKQEALLAAISEKD 946
Cdd:PTZ00121  1743 KKKAEEAKKDEEEKKK-IAHLKKEEEKKAEEIRKEKEAVIEEELDEED 1789
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 373-973 3.51e-14

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 77.37  E-value: 3.51e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  373 DSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDT 452
Cdd:TIGR04523   66 DEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLT 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  453 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGtqagEIH 532
Cdd:TIGR04523  146 EIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLES----QIS 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  533 DLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDE 612
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  613 REKQEEID-TYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEEC--LKMETQL 689
Cdd:TIGR04523  302 NQKEQDWNkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIekLKKENQS 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  690 KKAHEATLEARASpELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKLhppyqv 769
Cdd:TIGR04523  382 YKQEIKNLESQIN-DLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEL------ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  770 svpapqhvggfVWDFLGNLTSRQvKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEEL 849
Cdd:TIGR04523  455 -----------IIKNLDNTRESL-ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSL 522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  850 EEALRESVQITAEREMVLAQEES---------ARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLR 920
Cdd:TIGR04523  523 KEKIEKLESEKKEKESKISDLEDelnkddfelKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI 602

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  921 AERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKD 973
Cdd:TIGR04523  603 KEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 331-610 2.64e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.71  E-value: 2.64e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  331 ERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDsaktkaLQTVIEMKDSKISSMERGLRDLEEEIQMLKS 410
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQ------LRKELEELSRQISALRKDLARLEAEVEQLEE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  411 NGALSTEEREEEMKQMEVYRShskfmknKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAA 490
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEE-------RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAA 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  491 ILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLK 570
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS 900

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2024339653  571 DRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDR 610
Cdd:TIGR02168  901 EELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 230-902 4.99e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 4.99e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  230 QALQDELRiQRDLNQLFQQDsssrtsepfvaELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESI 309
Cdd:COG1196    216 RELKEELK-ELEAELLLLKL-----------RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  310 KKLLEMLQSKGLSAKATEEDHERTRRLAEAemhvhhLESLLEQKEKENNMLREEIHRrfenapDSAKTKALQTVIEMKDS 389
Cdd:COG1196    284 EEAQAEEYELLAELARLEQDIARLEERRRE------LEERLEELEEELAELEEELEE------LEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  390 KISSMERGLRDLEEEIQMLKSngALSTEEREEEmkqmevyrshskfmknkigQVKQELSRKDTELLALQTKLETLTNQFS 469
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEA--ELAEAEEELE-------------------ELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  470 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQ 549
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  550 KKIENLQEQLRDKE-KQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEeidtyKKDIKD 628
Cdd:COG1196    491 ARLLLLLEAEADYEgFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVA-----AAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  629 LKEKvgiLQGDLTEKESSLLDLKEHASSLASSGLKKDSRlktLEIALEQKKEEclkmetQLKKAHEATLEARASPELSDR 708
Cdd:COG1196    566 LKAA---KAGRATFLPLDKIRARAALAAALARGAIGAAV---DLVASDLREAD------ARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  709 MQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKLHppyqvsvpapqhvggfvwdflgnl 788
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA------------------------ 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  789 tsrqvkDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLA 868
Cdd:COG1196    690 ------EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 2024339653  869 QEESARINAEKQVEEL----MMAME---KVKQELESMKAKL 902
Cdd:COG1196    764 ELERELERLEREIEALgpvnLLAIEeyeELEERYDFLSEQR 804
PTZ00121 PTZ00121
MAEBL; Provisional
 351-988 7.39e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.64  E-value: 7.39e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  351 EQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEE--REEEMKQMEV 428
Cdd:PTZ00121  1113 EARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAarKAEEVRKAEE 1192

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  429 YRSHSKFMKNKIGQvKQELSRKDTEllalqtkletlTNQFSDSKQHIEVLK-ESLTAKEQRAAILQTEVDALRLRLEEKE 507
Cdd:PTZ00121  1193 LRKAEDARKAEAAR-KAEEERKAEE-----------ARKAEDAKKAEAVKKaEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  508 TMLNKKTKQIQEIAEEKgTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKdrvkslQADTTNTDTAL 587
Cdd:PTZ00121  1261 RMAHFARRQAAIKAEEA-RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKK------KAEEAKKKADA 1333

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  588 TTLEEALAEKERTIERLKEQRDRDEREKQEEidtyKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSR 667
Cdd:PTZ00121  1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEE----KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADE 1409

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  668 LKTLEiALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLERevtRYREESSKAQAEVDRLLEILKEM--ENEKN 745
Cdd:PTZ00121  1410 LKKAA-AAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEE---AKKAEEAKKKAEEAKKADEAKKKaeEAKKA 1485

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  746 DKDKKIAELERKHASRklhppyqvsvpapqhvggfvwdflgnltSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE 825
Cdd:PTZ00121  1486 DEAKKKAEEAKKKADE----------------------------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD 1537

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  826 DNLNDSSQQLQDNLRK-----KDDRIEELEEALRESvqitAEREMVLAQEESARINAEKQVEELMM---------AMEKV 891
Cdd:PTZ00121  1538 EAKKAEEKKKADELKKaeelkKAEEKKKAEEAKKAE----EDKNMALRKAEEAKKAEEARIEEVMKlyeeekkmkAEEAK 1613

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  892 KQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDAniallelSSSKKKTQDEVAALKRE 971
Cdd:PTZ00121  1614 KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK-------AEEDKKKAEEAKKAEED 1686

                          650
                   ....*....|....*..
gi 2024339653  972 KDRLVQQLKQQTQNRMK 988
Cdd:PTZ00121  1687 EKKAAEALKKEAEEAKK 1703
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 387-756 9.42e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 9.42e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  387 KDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEemkqmevyrshskfmknkigqVKQELSRKDTELLALQTKLETLTN 466
Cdd:TIGR02168  668 TNSSILERRREIEELEEKIEELEEKIAELEKALAE---------------------LRKELEELEEELEQLRKELEELSR 726

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  467 QFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVN 546
Cdd:TIGR02168  727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  547 VLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE---KQEEIDTYK 623
Cdd:TIGR02168  807 ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEleaLLNERASLE 886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  624 KDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKE---ECLKMETQLKKAHEATLEAR 700
Cdd:TIGR02168  887 EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlsEEYSLTLEEAEALENKIEDD 966

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024339653  701 ASpELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELER 756
Cdd:TIGR02168  967 EE-EARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
391-934 1.97e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 71.63  E-value: 1.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  391 ISSMERGLRDLEEEIQMLKsngaLSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLtnqfSD 470
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIK----RRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKL----EK 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  471 SKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAE---------EKGTQAGEIHDLKDMLEVK 541
Cdd:PRK03918   229 EVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEkvkelkelkEKAEEYIKLSEFYEEYLDE 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  542 ERKVNV----LQKKIENLQEQLRD---KEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKER-----------TIER 603
Cdd:PRK03918   309 LREIEKrlsrLEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEElerlkkrltglTPEK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  604 LKEQRDRDEREKQEeidtYKKDIKDLKEKVGILQGDLTEKESSLLDLK---------------EHASSLASSGLKKDSRL 668
Cdd:PRK03918   389 LEKELEELEKAKEE----IEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgrelteEHRKELLEEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  669 KTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLE-----------IL 737
Cdd:PRK03918   465 EKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKekliklkgeikSL 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  738 KEMENEKNDKDKKIAELERKHASRKlhppyqvsvpapqhvggfvwdflgnltsRQVKDQNKKVANLKHKEQVEKKKSAQM 817
Cdd:PRK03918   545 KKELEKLEELKKKLAELEKKLDELE----------------------------EELAELLKELEELGFESVEELEERLKE 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  818 LEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQ-EESARINAEKQVEELMMAMEKVKQELE 896
Cdd:PRK03918   597 LEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKElEELEKKYSEEEYEELREEYLELSRELA 676

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 2024339653  897 SMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMK 934
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 333-746 6.02e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 6.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  333 TRRLAEAEMHVHHLESLleqkEKENNMLREEIhRRFENAPDSAKtkalqtviemkdSKISSMERGLRDLEEEIQMLKsng 412
Cdd:TIGR02169  670 RSEPAELQRLRERLEGL----KRELSSLQSEL-RRIENRLDELS------------QELSDASRKIGEIEKEIEQLE--- 729

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  413 alstEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIevLKESLTAKEQRAAIL 492
Cdd:TIGR02169  730 ----QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL--SHSRIPEIQAELSKL 803

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  493 QTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDR 572
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  573 VKSLQadttntdtalttleealAEKERTIERLKEQRDRdEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKE 652
Cdd:TIGR02169  884 LGDLK-----------------KERDELEAQLRELERK-IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE 945

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  653 HASSLASsglkkdsrlktleiaLEQKKEECLKMETQLKKAHEATLEAraspelsdrMQQLEREVTRYREESSKAQ---AE 729
Cdd:TIGR02169  946 IPEEELS---------------LEDVQAELQRVEEEIRALEPVNMLA---------IQEYEEVLKRLDELKEKRAkleEE 1001

                          410
                   ....*....|....*..
gi 2024339653  730 VDRLLEILKEMENEKND 746
Cdd:TIGR02169 1002 RKAILERIEEYEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 156-754 1.30e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 1.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  156 TQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSpELKKERALRKDEASKIT-IWKEQYRVLQEENQHMQMTIQALQD 234
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLE-ELRLEVSELEEEIEELQkELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  235 ELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIET----------------- 297
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEleeqletlrskvaqlel 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  298 QKQTLNARDESIKKLLEMLQSKglSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKT 377
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDR--RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  378 KALQTVIEMKD------SKISSMERGLRDLE------------------------------------------EEIQMLK 409
Cdd:TIGR02168  472 EAEQALDAAERelaqlqARLDSLERLQENLEgfsegvkallknqsglsgilgvlselisvdegyeaaieaalgGRLQAVV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  410 SNGALSTEEREEEMKQMEVYRSH---------------SKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQF---SDS 471
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRVTflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDL 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  472 KQHIEVLKE-------------------SLT--AKEQRAAIL--QTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQA 528
Cdd:TIGR02168  632 DNALELAKKlrpgyrivtldgdlvrpggVITggSAKTNSSILerRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  529 GEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQR 608
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  609 DRDEREKQ---EEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKM 685
Cdd:TIGR02168  792 EQLKEELKalrEALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL 871

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  686 ETQLKKAHEA-TLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAEL 754
Cdd:TIGR02168  872 ESELEALLNErASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 344-757 2.13e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 68.12  E-value: 2.13e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  344 HHLESLLEQKEKENNMLREEIHRRFEnapdsaKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEM 423
Cdd:TIGR04523  200 ELLLSNLKKKIQKNKSLESQISELKK------QNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  424 KQMEVYRSHSKFMKNKIGQVKQELS------------RKDTELLALQTKLETLTNQFSDSKQHIEVLKESLtakeqraAI 491
Cdd:TIGR04523  274 KELEQNNKKIKELEKQLNQLKSEISdlnnqkeqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQI-------SQ 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  492 LQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKD 571
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  572 RVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDrderEKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLL--- 648
Cdd:TIGR04523  427 EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRE----SLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKkln 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  649 -----------DLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAheatlearaspELSDRMQQLEREVT 717
Cdd:TIGR04523  503 eekkeleekvkDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKE-----------NLEKEIDEKNKEIE 571

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 2024339653  718 RYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERK 757
Cdd:TIGR04523  572 ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 436-856 4.78e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.93  E-value: 4.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  436 MKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 515
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  516 QIQEIAEEKGTQAGEIHDLKDMLevkerkvnvLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALA 595
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARL---------SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  596 EKERTIERLKEQRDrderEKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKehasslassglKKDSRLKTLEIAL 675
Cdd:TIGR02169  837 ELQEQRIDLKEQIK----SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK-----------KERDELEAQLREL 901

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  676 EQKKEEcLKMETQLKKAHEATLEARASpELSDRMQQLEREVTRyREESSKAQAEVDRLLEILKEMENEkndkdkkiaele 755
Cdd:TIGR02169  902 ERKIEE-LEAQIEKKRKRLSELKAKLE-ALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEE------------ 966

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  756 rkhaSRKLHPpyqVSVPAPQHvggfvwdflgnltsrqvkdqnkkvanlkhkeqvekkksaqmLEEARRREDNLNDSSQQL 835
Cdd:TIGR02169  967 ----IRALEP---VNMLAIQE-----------------------------------------YEEVLKRLDELKEKRAKL 998

                          410       420
                   ....*....|....*....|.
gi 2024339653  836 QDNLRKKDDRIEELEEALRES 856
Cdd:TIGR02169  999 EEERKAILERIEEYEKKKREV 1019
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
192-744 8.95e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.16  E-value: 8.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  192 PELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDlnQLFQQDSSSRTSEPFVAELTEenFQRLH 271
Cdd:PRK03918   217 PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEE--RIEELKKEIEELEEKVKELKE--LKEKA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  272 TEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLE 351
Cdd:PRK03918   293 EEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  352 Q----KEKENNMLREEIHRRFENApdSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSN-------GALSTEERE 420
Cdd:PRK03918   373 ElerlKKRLTGLTPEKLEKELEEL--EKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvcGRELTEEHR 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  421 EEMkqMEVYRSHSKfmknKIGQVKQELSRKDTELLALQTKLETLTNQFSdskqhiEVLKESLTAKEQRAAILQTEVdalr 500
Cdd:PRK03918   451 KEL--LEEYTAELK----RIEKELKEIEEKERKLRKELRELEKVLKKES------ELIKLKELAEQLKELEEKLKK---- 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  501 LRLEEketmLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEvkerKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADT 580
Cdd:PRK03918   515 YNLEE----LEKKAEEYEKLKEKLIKLKGEIKSLKKELE----KLEELKKKLAELEKKLDELEEELAELLKELEELGFES 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  581 TNTDTALTTLEEALAEK-------ERTIERLKEQRDRDERE---KQEEIDTYKKDIKDLKEKVGILQGDLTEKESSllDL 650
Cdd:PRK03918   587 VEELEERLKELEPFYNEylelkdaEKELEREEKELKKLEEEldkAFEELAETEKRLEELRKELEELEKKYSEEEYE--EL 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  651 KEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYR-EESSKAQAE 729
Cdd:PRK03918   665 REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKaLLKERALSK 744

                          570
                   ....*....|....*.
gi 2024339653  730 VDRLL-EILKEMENEK 744
Cdd:PRK03918   745 VGEIAsEIFEELTEGK 760
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
285-757 1.11e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.75  E-value: 1.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  285 RKTLEEMELRIETQKQTLNARDEsIKKLLEMLQskglsakATEEDHERTRrlAEAEMHVHHLESLLEQKEKENNMLREEI 364
Cdd:PRK02224   233 RETRDEADEVLEEHEERREELET-LEAEIEDLR-------ETIAETERER--EELAEEVRDLRERLEELEEERDDLLAEA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  365 HRrfenapDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVK 444
Cdd:PRK02224   303 GL------DDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAR 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  445 QELSRKDTELLALQTKLETLTNQFSDS-------KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK----- 512
Cdd:PRK02224   377 EAVEDRREEIEELEEEIEELRERFGDApvdlgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpe 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  513 --KTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLqEQLRDKEKQMSSLKDRVKSLQadttntdTALTTL 590
Cdd:PRK02224   457 cgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLE-------ELIAER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  591 EEALAEKERTIERLKEQRDRDE---REKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGlKKDSR 667
Cdd:PRK02224   529 RETIEEKRERAEELRERAAELEaeaEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIA-DAEDE 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  668 LKTLEIALEQKKEeclkMETQLKKaheaTLEaraspELSDRMQQLERE-----VTRYREESSKAQAEVDRLLEILKEMEN 742
Cdd:PRK02224   608 IERLREKREALAE----LNDERRE----RLA-----EKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELRE 674

                          490
                   ....*....|....*
gi 2024339653  743 EKNDKDKKIAELERK 757
Cdd:PRK02224   675 ERDDLQAEIGAVENE 689
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 437-645 2.55e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.55  E-value: 2.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  437 KNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQ 516
Cdd:COG4942     33 QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRA 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  517 IQEIAEEKGTQ----AGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEE 592
Cdd:COG4942    113 LYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEA 192

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  593 ALAEKERTIERLKeqrdRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKES 645
Cdd:COG4942    193 LKAERQKLLARLE----KELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
275-762 3.40e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.23  E-value: 3.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  275 ERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKE 354
Cdd:PRK03918   227 EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  355 KENNMLREEIhrrfenapdsAKTKALQTVIEMKDSKISSMERGLRDLEEEI-QMLKSNGALSTEEREEEM---KQMEVYR 430
Cdd:PRK03918   307 DELREIEKRL----------SRLEEEINGIEERIKELEEKEERLEELKKKLkELEKRLEELEERHELYEEakaKKEELER 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  431 SHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLtaKEQRAAILQTEVDALRLRLEEKETML 510
Cdd:PRK03918   377 LKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAI--EELKKAKGKCPVCGRELTEEHRKELL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  511 NKKTKQIQEIAEEKgtqaGEIHDLKDMLEVKERKVNVLQKKIENLQeQLRDKEKQMSSLKDRVKSLQADTTNTDTAL-TT 589
Cdd:PRK03918   455 EEYTAELKRIEKEL----KEIEEKERKLRKELRELEKVLKKESELI-KLKELAEQLKELEEKLKKYNLEELEKKAEEyEK 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  590 LEEALAEKERTIERLKEQRDRDErEKQEEIDTYKKDIKDLKEKVGILQGDLTEKE-SSLLDLKEHASSLASSgLKKDSRL 668
Cdd:PRK03918   530 LKEKLIKLKGEIKSLKKELEKLE-ELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPF-YNEYLEL 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  669 KTLEIALEQKKEECLKMETQLKKAHEATLEARAS-PELSDRMQQLEREVT-----RYREESSKAQAEVDRLLEILKEMEN 742
Cdd:PRK03918   608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRlEELRKELEELEKKYSeeeyeELREEYLELSRELAGLRAELEELEK 687

                          490       500
                   ....*....|....*....|
gi 2024339653  743 EKNDKDKKIAELERKHASRK 762
Cdd:PRK03918   688 RREEIKKTLEKLKEELEERE 707
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
384-932 3.64e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 61.21  E-value: 3.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  384 IEMKDSK-----ISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHskfmKNKIGQVKQELSRKDTELLALQ 458
Cdd:PRK02224   196 IEEKEEKdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  459 TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKET-------MLNKKTKQIQEIAEEKGTQAGEI 531
Cdd:PRK02224   272 REREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDrdeelrdRLEECRVAAQAHNEEAESLREDA 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  532 HDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQAD----TTNTDTALTTLEEALAEKERTIERLKEQ 607
Cdd:PRK02224   352 DDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdaPVDLGNAEDFLEELREERDELREREAEL 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  608 R-----DRDEREKQEEI------DTYKKDIKDLKEKVGIlqgdlTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALE 676
Cdd:PRK02224   432 EatlrtARERVEEAEALleagkcPECGQPVEGSPHVETI-----EEDRERVEELEAELEDLEEEVEEVEERLERAEDLVE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  677 -----QKKEECLKMETQLKKAHEATLEAR--ASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDK 749
Cdd:PRK02224   507 aedriERLEERREDLEELIAERRETIEEKreRAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKE 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  750 KIAELERkhasrklhppyqvsvpapqhvggfvwdflgnltsrqVKDQNKKVANLkhkeqvekkksAQMLEEARRREDNLN 829
Cdd:PRK02224   587 RIESLER------------------------------------IRTLLAAIADA-----------EDEIERLREKREALA 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  830 DSSQQLQDNLRKKDDRIEELEEALRESvqitaeremVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSL 909
Cdd:PRK02224   620 ELNDERRERLAEKRERKRELEAEFDEA---------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL 690

                          570       580
                   ....*....|....*....|...
gi 2024339653  910 AEkethLTNLRaERRKHLEEVLE 932
Cdd:PRK02224   691 EE----LEELR-ERREALENRVE 708
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 144-896 4.27e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 4.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  144 RQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFwSPELKKERALRKDEASKITIWKEQYRVLQEENQ 223
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL-EAELEELEAELEELESRLEELEEQLETLRSKVA 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  224 HMQMTIQALQDELRIQRDLnqlfQQDSSSRtsepfVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLN 303
Cdd:TIGR02168  390 QLELQIASLNNEIERLEAR----LERLEDR-----RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  304 ARDESIKKLLEMLQSKGLSAKateedhertRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTV 383
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAE---------RELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISV 531

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  384 IEMKDSKISSmerglrDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSH---------------SKFMKNKIGQVKQELS 448
Cdd:TIGR02168  532 DEGYEAAIEA------ALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTflpldsikgteiqgnDREILKNIEGFLGVAK 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  449 RKDTELLALQTKLETLTNQF---SDSKQHIEVLKEslTAKEQRAAILQTEVDALRLRL----EEKETMLNKKTKQIQEIA 521
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVlvvDDLDNALELAKK--LRPGYRIVTLDGDLVRPGGVItggsAKTNSSILERRREIEELE 683

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  522 EEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTI 601
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  602 ERLKEQRDrderEKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEhasslassglkkdsRLKTLEIALEQKKEE 681
Cdd:TIGR02168  764 EELEERLE----EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA--------------ELTLLNEEAANLRER 825

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  682 CLKMETQLKkaheatlearaspELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASR 761
Cdd:TIGR02168  826 LESLERRIA-------------ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL 892

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  762 KLHppyqvsvpapqhvggfvwdfLGNLtSRQVKDQNKKVANLKHkeqvEKKKSAQMLEEARRREDNLNDSSQQLQDNLRk 841
Cdd:TIGR02168  893 RSE--------------------LEEL-SEELRELESKRSELRR----ELEELREKLAQLELRLEGLEVRIDNLQERLS- 946

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024339653  842 kDDRIEELEEALRESVQITAEREmvLAQEESARInaEKQVEEL----MMAMEKVKQELE 896
Cdd:TIGR02168  947 -EEYSLTLEEAEALENKIEDDEE--EARRRLKRL--ENKIKELgpvnLAAIEEYEELKE 1000
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
460-972 6.32e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 6.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  460 KLETLTNQFSDSKQHIE-VLKESLTAKEQ-RAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDM 537
Cdd:PRK02224   163 KLEEYRERASDARLGVErVLSDQRGSLDQlKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  538 LEVKERK---VNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALttlEEALAEKER------TIERLKEQR 608
Cdd:PRK02224   243 LEEHEERreeLETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER---DDLLAEAGLddadaeAVEARREEL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  609 DRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLassglkkDSRLKTLEIALEQKKEECLKMETQ 688
Cdd:PRK02224   320 EDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAEL-------ESELEEAREAVEDRREEIEELEEE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  689 LKKAHEATLEARASPElsdrmqqlerEVTRYREEsskAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKLhPPYQ 768
Cdd:PRK02224   393 IEELRERFGDAPVDLG----------NAEDFLEE---LREERDELREREAELEATLRTARERVEEAEALLEAGKC-PECG 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  769 VSVPAPQHVGGfvwdflgnltsrqVKDQNKKVANLkhkeqvekkksAQMLEEARRREDNLNDSSQQLQDnLRKKDDRIEE 848
Cdd:PRK02224   459 QPVEGSPHVET-------------IEEDRERVEEL-----------EAELEDLEEEVEEVEERLERAED-LVEAEDRIER 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  849 LEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLrAERRKHLE 928
Cdd:PRK02224   514 LEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL-KERIESLE 592

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 2024339653  929 EVlemkqEALLAAISEKDANIALLElssSKKKTQDEVAALKREK 972
Cdd:PRK02224   593 RI-----RTLLAAIADAEDEIERLR---EKREALAELNDERRER 628
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 521-766 9.64e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 9.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  521 AEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQAdttntdtALTTLEEALAEKERT 600
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQ-------ELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  601 IERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLAS--SGLKKD-SRLKTLEIALEQ 677
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREqaEELRADlAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  678 KKEECLKMETQLKKAHEATLEARAspELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERK 757
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKA--ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFA 249


                   ....*....
gi 2024339653  758 HASRKLHPP 766
Cdd:COG4942    250 ALKGKLPWP 258
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 392-981 9.93e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 59.75  E-value: 9.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  392 SSMERGLRDLEEEIQMLKsnGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDS 471
Cdd:pfam15921  220 SAISKILRELDTEISYLK--GRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  472 KQHIEVLKESltAKEQRA------AILQTEVDALRLRLEEKETMLNKKTKQIQ------------------EIAEEKGTQ 527
Cdd:pfam15921  298 QSQLEIIQEQ--ARNQNSmymrqlSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanseltearterdQFSQESGNL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  528 AGEIHDLKDMLEVKERKVNVLQKK--------------IENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEA 593
Cdd:pfam15921  376 DDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQG 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  594 LAEKERTIERLKEQRDRDE---REKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASS---GLKKDSR 667
Cdd:pfam15921  456 KNESLEKVSSLTAQLESTKemlRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdlKLQELQH 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  668 LKTLEIALEQKKEECLKMETQLKKAHEATLEARASPE-LSDRMQQLEREVTRYREESSKAQAEV-DRLLEiLKEMENEKN 745
Cdd:pfam15921  536 LKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIEnMTQLVGQHGRTAGAMQVEKAQLEKEInDRRLE-LQEFKILKD 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  746 DKDKKIAELERKHASRKLHPPYQVSVpapqhvggfvwdflGNLTSRQVKDQnkkvanlkhkeqveKKKSAQMLEEARRRE 825
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKLVNA--------------GSERLRAVKDI--------------KQERDQLLNEVKTSR 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  826 DNLNDSSQQ---LQDNLRKKDDRIEELEEALRESVQiTAEREmvLAQEESARINAEKQVEELMMAMEKVKQELESMKAKL 902
Cdd:pfam15921  667 NELNSLSEDyevLKRNFRNKSEEMETTTNKLKMQLK-SAQSE--LEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI 743

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024339653  903 SSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQ 981
Cdd:pfam15921  744 DALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAE 822
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 504-978 1.19e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.35  E-value: 1.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  504 EEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNT 583
Cdd:pfam05483  229 EEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRS 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  584 DTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLK 663
Cdd:pfam05483  309 MSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQK 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  664 KDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENE 743
Cdd:pfam05483  389 KSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEH 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  744 KNdkdKKIAELERKHASRKLHPPYQVSVPAPQHVGGFVWDFLGNLTSRQVKDQNKKVANLKHKEQvekkKSAQMLEEARR 823
Cdd:pfam05483  469 YL---KEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEE----RMLKQIENLEE 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  824 REDNLNDSSQQLQDNLRKKDD----RIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMK 899
Cdd:pfam05483  542 KEMNLRDELESVREEFIQKGDevkcKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK 621

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024339653  900 AKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQ 978
Cdd:pfam05483  622 KKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQH 700
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 275-936 1.34e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  275 ERQAKELFLLRKTLEEMELRIETQKQTLN------ARDESIKKLLEMLQSKGLSAKATE-EDHER-----TRRLAEAEMH 342
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLErlrrerEKAERYQALLKEKREYEGYELLKEkEALERqkeaiERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  343 VHHLESLLEQKEKENN---MLREEIHRRFEnAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIqmlksngalstEER 419
Cdd:TIGR02169  253 LEKLTEEISELEKRLEeieQLLEELNKKIK-DLGEEEQLRVKEKIGELEAEIASLERSIAEKEREL-----------EDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  420 EEEMKQMEVyrshskfmknKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDAL 499
Cdd:TIGR02169  321 EERLAKLEA----------EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  500 RLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQAD 579
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  580 TTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEID--------------------------------- 620
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARaseervRGGRAVEEVLKasiqgvhgtvaqlgsvgeryataievaagnrln 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  621 --------TYKKDIKDLKEKVG---------------------------------------------------------- 634
Cdd:TIGR02169  551 nvvveddaVAKEAIELLKRRKAgratflplnkmrderrdlsilsedgvigfavdlvefdpkyepafkyvfgdtlvvedie 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  635 ------------ILQGDLTEK---------------------ESSLLDLKEHASSLA---SSGLKKDSRLKTLEIALEQK 678
Cdd:TIGR02169  631 aarrlmgkyrmvTLEGELFEKsgamtggsraprggilfsrsePAELQRLRERLEGLKrelSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  679 KEECLKMETQLKKAHEATLEARASpeLSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKH 758
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQLEQEEEK--LKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  759 ASRKlhppyqvsvpapqhvggfvWDFLGNLTSRQVKDQNKKVANLKHKEQVEKKKSaQMLEEARRREDNLNDSSQQLQDN 838
Cdd:TIGR02169  789 SHSR-------------------IPEIQAELSKLEEEVSRIEARLREIEQKLNRLT-LEKEYLEKEIQELQEQRIDLKEQ 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  839 LRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTN 918
Cdd:TIGR02169  849 IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          810
                   ....*....|....*...
gi 2024339653  919 LrAERRKHLEEVLEMKQE 936
Cdd:TIGR02169  929 L-EEELSEIEDPKGEDEE 945
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
550-991 1.77e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.63  E-value: 1.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  550 KKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTAlttlEEALAEKERTIERLkeQRDRDEREKQEEIDTYKKDIKDL 629
Cdd:COG4717     64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEEL----EEELEELEAELEEL--REELEKLEKLLQLLPLYQELEAL 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  630 KEKVGILQGDLTEKESSLLDLKEhasslassglkKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEaraspELSDRM 709
Cdd:COG4717    138 EAELAELPERLEELEERLEELRE-----------LEEELEELEAELAELQEELEELLEQLSLATEEELQ-----DLAEEL 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  710 QQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKD--KKIAELERKHASR----KLHPPYQVSVPAPQHVGGFVWD 783
Cdd:COG4717    202 EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAleERLKEARLLLLIAaallALLGLGGSLLSLILTIAGVLFL 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  784 FLGNLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE--DNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITA 861
Cdd:COG4717    282 VLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEllAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  862 EREMVLAQEESARINAEKQVEELMMAMEKVKQ--ELESMKAKLSSTQQSLAEK----ETHLTNLRAERRKHLEEVLEMKQ 935
Cdd:COG4717    362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQaeEYQELKEELEELEEQLEELlgelEELLEALDEEELEEELEELEEEL 441

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024339653  936 EALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMA 991
Cdd:COG4717    442 EELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKL 497
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 480-726 4.53e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.70  E-value: 4.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  480 ESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQL 559
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  560 RDKEKQmssLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDerekQEEIDTYKKDIKDLKEKVGILQGD 639
Cdd:COG4942    100 EAQKEE---LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPAR----REQAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  640 LTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKkaheatlearaspELSDRMQQLEREVTRY 719
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE-------------ELEALIARLEAEAAAA 239


                   ....*..
gi 2024339653  720 REESSKA 726
Cdd:COG4942    240 AERTPAA 246
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 446-633 6.79e-08

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 54.55  E-value: 6.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  446 ELSRKDTELLALQTKLETLtnqfsdsKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEekg 525
Cdd:COG1579     11 DLQELDSELDRLEHRLKEL-------PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE--- 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  526 tQAGEIHDLKDMlevkerkvNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQAdttntdtALTTLEEALAEKERTIERLK 605
Cdd:COG1579     81 -QLGNVRNNKEY--------EALQKEIESLKRRISDLEDEILELMERIEELEE-------ELAELEAELAELEAELEEKK 144

                          170       180
                   ....*....|....*....|....*...
gi 2024339653  606 EQRDRDEREKQEEIDTYKKDIKDLKEKV 633
Cdd:COG1579    145 AELDEELAELEAELEELEAEREELAAKI 172
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 154-941 7.99e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 7.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALrkdEASKITIWKEQYRvLQEENQHMQMTIQALQ 233
Cdd:TIGR02169  189 LDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEAL---ERQKEAIERQLAS-LEEELEKLTEEISELE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  234 DEL-RIQRDLNQLFQQdsssrtsepfVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKL 312
Cdd:TIGR02169  265 KRLeEIEQLLEELNKK----------IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  313 LEmlQSKGLSAKATEEDHER---TRRLAEAEMHVHHLESLLEQKEKENNMLREEiHRRFENAPDSAKTK---------AL 380
Cdd:TIGR02169  335 LA--EIEELEREIEEERKRRdklTEEYAELKEELEDLRAELEEVDKEFAETRDE-LKDYREKLEKLKREinelkreldRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  381 QTVIEMKDSKISSMERGLRDLEEEIQMLKSNG-------ALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTE 453
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKedkaleiKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  454 LLALQTKLETLTNQFSDSKQHIEVLKESLTA-----------KEQRAAILQ-------------TEVDA------LRLRL 503
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlgsvGERYATAIEvaagnrlnnvvveDDAVAkeaielLKRRK 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  504 EEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVL---------------------QKKIENLQEQLRDK 562
Cdd:TIGR02169  572 AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFkyvfgdtlvvedieaarrlmgKYRMVTLEGELFEK 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  563 EKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER---EKQEEIDTYKKDIKDLKEKVGILQGD 639
Cdd:TIGR02169  652 SGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENrldELSQELSDASRKIGEIEKEIEQLEQE 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  640 LTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAhEATLEARASPELSDRMQQLEREVTRY 719
Cdd:TIGR02169  732 EEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL-EARLSHSRIPEIQAELSKLEEEVSRI 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  720 REESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKlhppyqvsvPAPQHVGGFVWDFLGNL--TSRQVKDQN 797
Cdd:TIGR02169  811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE---------KEIENLNGKKEELEEELeeLEAALRDLE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  798 KKVANLKHKEQVEKKKsaqmLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESAR-IN 876
Cdd:TIGR02169  882 SRLGDLKKERDELEAQ----LRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEdVQ 957

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  877 AEKQ-VEELMMAMEKVK----QELESMKAKLSstqqSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAA 941
Cdd:TIGR02169  958 AELQrVEEEIRALEPVNmlaiQEYEEVLKRLD----ELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
537-758 1.51e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 1.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  537 MLEVKErkvnvLQKKIENLQEQ---LRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEaLAEKERTIERLKEQRDRDER 613
Cdd:COG4913    217 MLEEPD-----TFEAADALVEHfddLERAHEALEDAREQIELLEPIRELAERYAAARER-LAELEYLRAALRLWFAQRRL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  614 EK-QEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEhasSLASSGLKK----DSRLKTLEIALEQKKEECLKMETQ 688
Cdd:COG4913    291 ELlEAELEELRAELARLEAELERLEARLDALREELDELEA---QIRGNGGDRleqlEREIERLERELEERERRRARLEAL 367

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  689 LKKAHEATLEARAspELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKH 758
Cdd:COG4913    368 LAALGLPLPASAE--EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
499-980 2.38e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.07  E-value: 2.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  499 LRLRLEEKETMLnKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQA 578
Cdd:PRK03918   174 IKRRIERLEKFI-KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  579 DTTNTDTALTTLEEALAEKERTIERLKEQRDRDE--REKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASS 656
Cdd:PRK03918   253 SKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKE 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  657 LASsglkKDSRLKTLEialeQKKEECLKMETQLKKAHEATLEARAspeLSDRMQQLEREVTRYreesskaqaEVDRLLEI 736
Cdd:PRK03918   333 LEE----KEERLEELK----KKLKELEKRLEELEERHELYEEAKA---KKEELERLKKRLTGL---------TPEKLEKE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  737 LKEMENEKNDKDKKIAELERKhasrklhppyqvsvpapqhvggfvwdfLGNLTSRqVKDQNKKVANLKH--------KEQ 808
Cdd:PRK03918   393 LEELEKAKEEIEEEISKITAR---------------------------IGELKKE-IKELKKAIEELKKakgkcpvcGRE 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  809 VEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMV----LAQEESARINAEKqVEEL 884
Cdd:PRK03918   445 LTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqlkELEEKLKKYNLEE-LEKK 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  885 MMAMEKVKQELESMKAKLSSTQQSLaEKETHLTNLRAERRKHLEEVLEMKQEAL-----LAAISEKDANIAL-------- 951
Cdd:PRK03918   524 AEEYEKLKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDELEEELAELLkeleeLGFESVEELEERLkelepfyn 602

                          490       500       510
                   ....*....|....*....|....*....|.
gi 2024339653  952 --LELSSSKKKTQDEVAALKREKDRLVQQLK 980
Cdd:PRK03918   603 eyLELKDAEKELEREEKELKKLEEELDKAFE 633
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 259-945 3.16e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.97  E-value: 3.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  259 VAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAE 338
Cdd:TIGR00618  181 LALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQ 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  339 AEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEE 418
Cdd:TIGR00618  261 LLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSI 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  419 REEEMKQMEVYRSHSKFMK--NKIGQVKQELSRKDTE---LLALQTKLETLTNQFSDSKQhievLKESLTAKEQRAAILQ 493
Cdd:TIGR00618  341 EEQRRLLQTLHSQEIHIRDahEVATSIREISCQQHTLtqhIHTLQQQKTTLTQKLQSLCK----ELDILQREQATIDTRT 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  494 TEVDALRLRL--EEKETMLNKKTKQIQEIAEEKGTQ---AGEIH----------------DLKDMLEVKERKVNVLQKKI 552
Cdd:TIGR00618  417 SAFRDLQGQLahAKKQQELQQRYAELCAAAITCTAQcekLEKIHlqesaqslkereqqlqTKEQIHLQETRKKAVVLARL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  553 ENLQEQLRDKEKQMSSLK------DRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKK-- 624
Cdd:TIGR00618  497 LELQEEPCPLCGSCIHPNparqdiDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSIlt 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  625 -DIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSG----LKKDSRLKTLEIAL-EQKKEECLKMETQLKKAHEATLE 698
Cdd:TIGR00618  577 qCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQhallRKLQPEQDLQDVRLhLQQCSQELALKLTALHALQLTLT 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  699 ARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHaSRKLHPPYQVSVPAPQHVG 778
Cdd:TIGR00618  657 QERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEY-DREFNEIENASSSLGSDLA 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  779 GfvwdflgnltsrQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQ 858
Cdd:TIGR00618  736 A------------REDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKT 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  859 ITAEREMVLAQEEsarinaekqvEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLrAERRKHLEEVleMKQEAL 938
Cdd:TIGR00618  804 LEAEIGQEIPSDE----------DILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKY-EECSKQLAQL--TQEQAK 870


                   ....*..
gi 2024339653  939 LAAISEK 945
Cdd:TIGR00618  871 IIQLSDK 877
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
445-642 3.57e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.54  E-value: 3.57e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  445 QELSRKDTELLALQTKLETLtnqfsdskQHIEVLKESLTAKEQRAAILQTEVDALRLrlEEKETMLNKKTKQIQEIAEEK 524
Cdd:COG4913    235 DDLERAHEALEDAREQIELL--------EPIRELAERYAAARERLAELEYLRAALRL--WFAQRRLELLEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  525 GTQAGEIHDLKDMLEVKERKVNVLQ--------KKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAE 596
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEaqirgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAA 384

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2024339653  597 KERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTE 642
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
RBD-FIP pfam09457
FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of ...
 1076-1116 3.85e-07

FIP domain; The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of Rab11-interacting proteins (FIPs). The Rab proteins constitute the largest family of small GTPases (>60 members in mammals). Among them Rab11 is a well characterized regulator of endocytic and recycling pathways. Rab11 associates with a broad range of post-Golgi organelles, including recycling endosomes.


Pssm-ID: 462805 [Multi-domain]  Cd Length: 41  Bit Score: 47.33  E-value: 3.85e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 2024339653 1076 TQEQLRDELEKGEKESAELQEFANAILQQIADHCPDILEQV 1116
Cdd:pfam09457    1 SRDELQDALQKQEEENRRLEDYIDNILLRIMEHNPSILEVP 41
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 193-1033 4.47e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.21  E-value: 4.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  193 ELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEpfvaeLTEENFQRLHT 272
Cdd:pfam02463  203 KEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEK-----LAQVLKENKEE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  273 EHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEaemhvhhLESLLEQ 352
Cdd:pfam02463  278 EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKE-------LKELEIK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  353 KEKENNmlreeihrrfenapdsaktkalqtviemkdsKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSH 432
Cdd:pfam02463  351 REAEEE-------------------------------EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  433 SKFMKNKIGQVKQELSRKDTELLALQTKLETLtnqfsdskqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK 512
Cdd:pfam02463  400 KSEEEKEAQLLLELARQLEDLLKEEKKEELEI----------LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  513 KTKQIQEI--AEEKGTQAGEIHDLKDMLEV-KERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTT 589
Cdd:pfam02463  470 SEDLLKETqlVKLQEQLELLLSRQKLEERSqKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  590 LEEALAEKERTIERLKEQR-----DRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKK 664
Cdd:pfam02463  550 IVEVSATADEVEERQKLVRaltelPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGIL 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  665 DSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEK 744
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  745 NDKDKKIAELERKHASRKlhppyqvsvpapqhvggfvwdflgnltSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 824
Cdd:pfam02463  710 EELKKLKLEAEELLADRV---------------------------QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  825 EDNLNDSSQQLQDNLRKKDDRIEELEEA-LRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLS 903
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEeKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  904 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLElssSKKKTQDEVAALKREKDRLVQQLKQQT 983
Cdd:pfam02463  843 KEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKE---EKEKEEKKELEEESQKLNLLEEKENEI 919

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024339653  984 QNRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKL 1033
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAK 969
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 402-1001 5.12e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.21  E-value: 5.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  402 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKES 481
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  482 LTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRD 561
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  562 KEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQE------EIDTYKKDIKDLKEKVGI 635
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEelelksEEEKEAQLLLELARQLED 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  636 LQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLERE 715
Cdd:pfam02463  420 LLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  716 V--TRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRK---LHPPYQVSVPAPQHVGGFVWDFLGNLTS 790
Cdd:pfam02463  500 QkeSKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAvivEVSATADEVEERQKLVRALTELPLGARK 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  791 RQVKDQNKKVANLKHKEQ---VEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVL 867
Cdd:pfam02463  580 LRLLIPKLKLPLKSIAVLeidPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLA 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  868 AQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKda 947
Cdd:pfam02463  660 EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEE-- 737

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024339653  948 nialLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHLKS 1001
Cdd:pfam02463  738 ----LKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
176-640 5.57e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 5.57e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  176 ESKLSSSMNSIKTFwspELKKERAL-RKDEASKITIWKEQYR----VLQEENQHMQMTI-------QALQDELRIQRDLN 243
Cdd:PRK02224   212 ESELAELDEEIERY---EEQREQAReTRDEADEVLEEHEERReeleTLEAEIEDLRETIaetererEELAEEVRDLRERL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  244 QLFQQDSSSRTSEpfvAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlQSKGLSA 323
Cdd:PRK02224   289 EELEEERDDLLAE---AGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE--RAEELRE 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  324 KATEEDHErtrrLAEAEMHVHHLESLLEQKEKENNMLREeihrRFENAPDS--AKTKALQTVIEMKD---SKISSMERGL 398
Cdd:PRK02224   364 EAAELESE----LEEAREAVEDRREEIEELEEEIEELRE----RFGDAPVDlgNAEDFLEELREERDelrEREAELEATL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  399 RDLEEEI----------------QMLK-SNGALSTEEREEEMKQMEVYRSHskfMKNKIGQVKQELSRKdTELLALQTKL 461
Cdd:PRK02224   436 RTARERVeeaealleagkcpecgQPVEgSPHVETIEEDRERVEELEAELED---LEEEVEEVEERLERA-EDLVEAEDRI 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  462 ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVK 541
Cdd:PRK02224   512 ERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  542 ERKVNVLQKkIENLQEQ---LRDKEKQMSSLKD-----------------------RVKSLQADTTNTDTALTTLEEALA 595
Cdd:PRK02224   592 ERIRTLLAA-IADAEDEierLREKREALAELNDerrerlaekrerkreleaefdeaRIEEAREDKERAEEYLEQVEEKLD 670

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024339653  596 EK--------------ERTIERLKEQRDRDER--EKQEEIDTYKKDIKDLKEKVGILQGDL 640
Cdd:PRK02224   671 ELreerddlqaeigavENELEELEELRERREAleNRVEALEALYDEAEELESMYGDLRAEL 731
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 459-988 1.14e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.92  E-value: 1.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  459 TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQ-IQEIAEEKGTQAGEIHDLKDM 537
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEkRDELNGELSAADAAVAKDRSE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  538 LEV-KERKVNVLQKKIENL---QEQLRDKEKQMSSLKDRVKSLqadttntdtalttlEEALAEKERTIERLKEQRDRDER 613
Cdd:pfam12128  324 LEAlEDQHGAFLDADIETAaadQEQLPSWQSELENLEERLKAL--------------TGKHQDVTAKYNRRRSKIKEQNN 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  614 EKQEEIDTYKKDIKDLKEK-VGILQGDLTEKESSLLDlkehasslassglkkdsrlkTLEIALEQKKEECLKMETQLKKA 692
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDRqLAVAEDDLQALESELRE--------------------QLEAGKLEFNEEEYRLKSRLGEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  693 HEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRL---LEILKEMENEKNDK--DKKIAELERKHASRKLHppy 767
Cdd:pfam12128  450 KLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLqseLRQARKRRDQASEAlrQASRRLEERQSALDELE--- 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  768 QVSVPAPQHVGGFV------W-DFLGNLTSR---------------QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE 825
Cdd:pfam12128  527 LQLFPQAGTLLHFLrkeapdWeQSIGKVISPellhrtdldpevwdgSVGGELNLYGVKLDLKRIDVPEWAASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  826 DnlndssqQLQDNLRKKDDRIEELEEALresVQITAEREMVLAQEESARI---NAEKQVEELMMAME----KVKQELESM 898
Cdd:pfam12128  607 D-------KAEEALQSAREKQAAAEEQL---VQANGELEKASREETFARTalkNARLDLRRLFDEKQsekdKKNKALAER 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  899 KAKLSSTQQSLAEKETHLTN----LRAERRKHLEEVLEMKQEALLAAISEKDANIALLElssskkktqDEVAALKREKDR 974
Cdd:pfam12128  677 KDSANERLNSLEAQLKQLDKkhqaWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLK---------AAIAARRSGAKA 747

                          570
                   ....*....|....
gi 2024339653  975 LVQQLKQQTQNRMK 988
Cdd:pfam12128  748 ELKALETWYKRDLA 761
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 446-617 1.36e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 52.14  E-value: 1.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  446 ELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAE--- 522
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARaly 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  523 EKGTQ---------AGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEA 593
Cdd:COG3883     97 RSGGSvsyldvllgSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180
                   ....*....|....*....|....
gi 2024339653  594 LAEKERTIERLKEQRDRDEREKQE 617
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAE 200
PRK01156 PRK01156
chromosome segregation protein; Provisional
 288-883 3.33e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 51.44  E-value: 3.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  288 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGL---SAKATEEDHERTRRLAEAEmhVHHLESLLEQKEKENNMLREEI 364
Cdd:PRK01156   164 LERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLeleNIKKQIADDEKSHSITLKE--IERLSIEYNNAMDDYNNLKSAL 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  365 HRrfenapdsakTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKsngalSTEEREEEMKQMEVYRSHSKF-----MKNK 439
Cdd:PRK01156   242 NE----------LSSLEDMKNRYESEIKTAESDLSMELEKNNYYK-----ELEERHMKIINDPVYKNRNYIndyfkYKND 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  440 IGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKEsltakeqraailQTEVDALRLRLEEKETMLNKKTKQIQE 519
Cdd:PRK01156   307 IENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSR------------YDDLNNQILELEGYEMDYNSYLKSIES 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  520 IAEEKGTQAGEIHDLKD----MLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEE--- 592
Cdd:PRK01156   375 LKKKIEEYSKNIERMSAfiseILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGqsv 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  593 ----ALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQgdlteKESSLLDLKEHASSLASSGLKKDSR- 667
Cdd:PRK01156   455 cpvcGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLK-----KRKEYLESEEINKSINEYNKIESARa 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  668 -LKTLEIALEQKKEECLKME---TQLKKAHEATLEARASPELSDRMQ----QLEREVTRYREESSKAQAEVDRLLEILKE 739
Cdd:PRK01156   530 dLEDIKIKINELKDKHDKYEeikNRYKSLKLEDLDSKRTSWLNALAVisliDIETNRSRSNEIKKQLNDLESRLQEIEIG 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  740 MENEKNDKDKKIAELERKhaSRKLHPPYQVSVPAPQHVggfvwdflgNLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLE 819
Cdd:PRK01156   610 FPDDKSYIDKSIREIENE--ANNLNNKYNEIQENKILI---------EKLRGKIDNYKKQIAEIDSIIPDLKEITSRIND 678

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024339653  820 EarrrEDNLNDSSQQLQD---NLRKKDDRIEELEEALRESVQITAEREMVLAQEES--ARINAEKQVEE 883
Cdd:PRK01156   679 I----EDNLKKSRKALDDakaNRARLESTIEILRTRINELSDRINDINETLESMKKikKAIGDLKRLRE 743
PTZ00121 PTZ00121
MAEBL; Provisional
 160-754 8.12e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 8.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  160 EVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKitiwkeqyrvlqeENQHMQMTIQALQDELRIQ 239
Cdd:PTZ00121  1275 EEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKK-------------KAEEAKKKADAAKKKAEEA 1341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  240 RDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKElflLRKTLEEMELRIETQKQTlnardESIKKLLEMLQSK 319
Cdd:PTZ00121  1342 KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA---AKKKAEEKKKADEAKKKA-----EEDKKKADELKKA 1413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  320 GLSAKATEEDHERTRRLAEAEMHVHHLEsllEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLR 399
Cdd:PTZ00121  1414 AAAKKKADEAKKKAEEKKKADEAKKKAE---EAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKK 1490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  400 DLEEeiqmlKSNGALSTEEREEEMKQMEVYRshskfmknkigqvKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLK 479
Cdd:PTZ00121  1491 KAEE-----AKKKADEAKKAAEAKKKADEAK-------------KAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  480 EsltAKEQRAAILQTEVDALRlRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDlkdmlEVKERKVNVLQKkienlQEQL 559
Cdd:PTZ00121  1553 K---AEELKKAEEKKKAEEAK-KAEEDKNMALRKAEEAKKAEEARIEEVMKLYE-----EEKKMKAEEAKK-----AEEA 1618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  560 RDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERlKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGD 639
Cdd:PTZ00121  1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK-AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE 1697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  640 LTEKESSlldlkEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEatlEARASPELSDRMQQLEREVTRY 719
Cdd:PTZ00121  1698 AEEAKKA-----EELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAE---EAKKDEEEKKKIAHLKKEEEKK 1769

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 2024339653  720 REESSKAQAEVDRlLEILKEMENEKNDKDKKIAEL 754
Cdd:PTZ00121  1770 AEEIRKEKEAVIE-EELDEEDEKRRMEVDKKIKDI 1803
PRK09039 PRK09039
peptidoglycan -binding protein;
445-577 1.17e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 48.81  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEK 524
Cdd:PRK09039    46 REISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQEL 125

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024339653  525 GTQAGEIHDlkdmlevKERKVNVLQKKIENLQEQL------------RDKEKQM----------SSLKDRVKSLQ 577
Cdd:PRK09039   126 DSEKQVSAR-------ALAQVELLNQQIAALRRQLaaleaaldasekRDRESQAkiadlgrrlnVALAQRVQELN 193
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
456-633 1.18e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 1.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  456 ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQ--TEVDALRLRLEEKETMLNKKTKQIQEIAEEKGtqagEIHD 533
Cdd:COG4913    614 ALEAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAELERLDASSD----DLAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  534 LKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER 613
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRE 769

                          170       180
                   ....*....|....*....|
gi 2024339653  614 EKQEEIDTYKKDIKDLKEKV 633
Cdd:COG4913    770 NLEERIDALRARLNRAEEEL 789
46 PHA02562
endonuclease subunit; Provisional
 565-757 1.20e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.24  E-value: 1.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  565 QMSSL-KDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEK 643
Cdd:PHA02562   167 EMDKLnKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  644 ESSLLDLKEHASSLASSGLKKDSRLKTLE--------------------------IALEQKKEECLKMETQLKKA----- 692
Cdd:PHA02562   247 VMDIEDPSAALNKLNTAAAKIKSKIEQFQkvikmyekggvcptctqqisegpdriTKIKDKLKELQHSLEKLDTAidele 326

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024339653  693 ---HEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLL-------EILKEMENEKNDKDKKIAELERK 757
Cdd:PHA02562   327 eimDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQaefvdnaEELAKLQDELDKIVKTKSELVKE 401
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 667-981 1.23e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  667 RLKTLEIALEqKKEECLKMETQLKKAhEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKND 746
Cdd:TIGR02169  199 QLERLRRERE-KAERYQALLKEKREY-EGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  747 KDKKIAELERKHASRKLHPPYQVSVPAPQHVGGFvwdflgNLTSRQVKDQNKKVANLK---HKEQVEKKKSAQMLEEARR 823
Cdd:TIGR02169  277 LNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI------AEKERELEDAEERLAKLEaeiDKLLAEIEELEREIEEERK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  824 REDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLS 903
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA 430

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024339653  904 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEalLAAISEKdaniaLLELSSSKKKTQDEVAALKREKDRLVQQLKQ 981
Cdd:TIGR02169  431 GIEAKINELEEEKEDKALEIKKQEWKLEQLAAD--LSKYEQE-----LYDLKEEYDRVEKELSKLQRELAEAEAQARA 501
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 193-652 1.25e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.55  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  193 ELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHT 272
Cdd:COG1196    324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  273 EHERQAKELFLLRKTLEEMELRIETQKQTLN-----ARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLE 347
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELEeeeeeEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  348 SLLEQKEKENNMLrEEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIqmlksngalstEEREEEMKQME 427
Cdd:COG1196    484 EELAEAAARLLLL-LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL-----------EAALAAALQNI 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  428 VYRSHSKfMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKE 507
Cdd:COG1196    552 VVEDDEV-AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA 630

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  508 TMLNKKtKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTAL 587
Cdd:COG1196    631 RLEAAL-RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024339653  588 TTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKE 652
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774
46 PHA02562
endonuclease subunit; Provisional
 414-686 1.83e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 48.86  E-value: 1.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  414 LSTEERE---EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNqfsdskqHIEVLKESltaKEQRAA 490
Cdd:PHA02562   147 LSAPARRklvEDLLDISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNK-------NIEEQRKK---NGENIA 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  491 ILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQE---------QLRD 561
Cdd:PHA02562   217 RKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKggvcptctqQISE 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  562 KEKQMSSLKDRVKSLQADttntdtalttleealaekertIERLKEQRDrDEREKQEEIDTYKKDIKDLKEKVGILQGDLT 641
Cdd:PHA02562   297 GPDRITKIKDKLKELQHS---------------------LEKLDTAID-ELEEIMDEFNEQSKKLLELKNKISTNKQSLI 354

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 2024339653  642 EKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEEC--LKME 686
Cdd:PHA02562   355 TLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKseLVKE 401
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 267-952 2.06e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.95  E-value: 2.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  267 FQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLleMLQSKGLSAKATEEDHERTRRLAEAEMHVHHL 346
Cdd:pfam05483   80 YSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQEL--QFENEKVSLKLEEEIQENKDLIKENNATRHLC 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  347 ESLLE------QKEKENNMLREEIHRRFEN----------APDSAKTKALQTVIEMKdSKISSMERGLRDLEEEIQMLKS 410
Cdd:pfam05483  158 NLLKEtcarsaEKTKKYEYEREETRQVYMDlnnniekmilAFEELRVQAENARLEMH-FKLKEDHEKIQHLEEEYKKEIN 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  411 NGA-------LSTEEREEEMKQMEVYRSHSKfmkNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHievLKESLT 483
Cdd:pfam05483  237 DKEkqvslllIQITEKENKMKDLTFLLEESR---DKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMS---LQRSMS 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  484 AKEQRAAILQTEVDALRLRLEEKETmlnkktkQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLR--- 560
Cdd:pfam05483  311 TQKALEEDLQIATKTICQLTEEKEA-------QMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKiit 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  561 -DKEKQMSSLKD--RVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQ 637
Cdd:pfam05483  384 mELQKKSSELEEmtKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIK 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  638 gdlTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKE---ECLKMETQLKKAHEATLEARASPElsdrmqQLER 714
Cdd:pfam05483  464 ---TSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKEltqEASDMTLELKKHQEDIINCKKQEE------RMLK 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  715 EVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKLHPPYQVSVPAPQhvggfvwdflGNLTSRQVK 794
Cdd:pfam05483  535 QIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENK----------CNNLKKQIE 604

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  795 DQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQ----------DNLRKKDDRIEELEEALRESVQ---ITA 861
Cdd:pfam05483  605 NKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELAsakqkfeeiiDNYQKEIEDKKISEEKLLEEVEkakAIA 684

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  862 EREMVLAQEESARinAEKQVEELMMAMEKVKQ-----------ELESMKAKLSSTQQSLAEKETHLTNLRAERRKhLEEV 930
Cdd:pfam05483  685 DEAVKLQKEIDKR--CQHKIAEMVALMEKHKHqydkiieerdsELGLYKNKEQEQSSAKAALEIELSNIKAELLS-LKKQ 761

                          730       740
                   ....*....|....*....|..
gi 2024339653  931 LEMKQEALLAAISEKDANIALL 952
Cdd:pfam05483  762 LEIEKEEKEKLKMEAKENTAIL 783
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
432-624 2.35e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  432 HSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLeeketmLN 511
Cdd:COG4913    261 AERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQI------RG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  512 KKTKQIQEIAEekgtqagEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQmssLKDRVKSLQADTTNTDTALTTLE 591
Cdd:COG4913    335 NGGDRLEQLER-------EIERLERELEERERRRARLEALLAALGLPLPASAEE---FAALRAEAAALLEALEEELEALE 404

                          170       180       190
                   ....*....|....*....|....*....|...
gi 2024339653  592 EALAEKERTIERLKEQRdrdeREKQEEIDTYKK 624
Cdd:COG4913    405 EALAEAEAALRDLRREL----RELEAEIASLER 433
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
499-954 5.31e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 5.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  499 LRLRLEEKETMLNKKTKQIQEIAEEkgtQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQA 578
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLK---ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  579 DTTNTDTALTTL--EEALAEKERTIERLKEQRdRDEREKQEEIDTYKKDIKDLKEKVG-ILQGDLTEKESSLLDLKEHAS 655
Cdd:COG4717    124 LLQLLPLYQELEalEAELAELPERLEELEERL-EELRELEEELEELEAELAELQEELEeLLEQLSLATEEELQDLAEELE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  656 SLASSGLKKDSRLKTLEIALEQKKEECLKMETQL------KKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAE 729
Cdd:COG4717    203 ELQQRLAELEEELEEAQEELEELEEELEQLENELeaaaleERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  730 VDRLLEILKEMENEKNDKDKKIAELERKHASRKLHPPYQVSVPAPQHvggfvwdFLGNLTSRQVKDQNKKVANLK--HKE 807
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALG-------LPPDLSPEELLELLDRIEELQelLRE 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  808 QVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALREsvQITAEREMVLAQEESARINAEKQVEELMMA 887
Cdd:COG4717    356 AEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEE--LEELEEQLEELLGELEELLEALDEEELEEE 433

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024339653  888 MEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRK-HLEEVLEMKQEALLAAISEKDANIALLEL 954
Cdd:COG4717    434 LEELEEELEELEEELEELREELAELEAELEQLEEDGELaELLQELEELKAELRELAEEWAALKLALEL 501
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 390-1094 6.20e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 6.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  390 KISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFS 469
Cdd:TIGR04523   41 KLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  470 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQ 549
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  550 KKIENLQ---EQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER---EKQEEIDTYK 623
Cdd:TIGR04523  201 LLLSNLKkkiQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKqlsEKQKELEQNN 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  624 KDIKDLKEkvgilqgDLTEKESSLLDLKEHASSLASSGLKKDsrlktleiaLEQKKEECLKMETQLKKAHEATlearasP 703
Cdd:TIGR04523  281 KKIKELEK-------QLNQLKSEISDLNNQKEQDWNKELKSE---------LKNQEKKLEEIQNQISQNNKII------S 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  704 ELSDRMQQLEREVTRYREESSKAQAEvdrLLEILKEMENEKNDKDKKIAELErkhasrklhppyqvsvpapqhvggfvwd 783
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEKQRE---LEEKQNEIEKLKKENQSYKQEIK---------------------------- 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  784 flgNLTSrQVKDQNKKvanLKHKEQVEKKKSAQMleearrrednlndssQQLQDNLRKKDDRIEELEEALRESVQITAER 863
Cdd:TIGR04523  388 ---NLES-QINDLESK---IQNQEKLNQQKDEQI---------------KKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  864 EMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEallaaIS 943
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK-----IS 520

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  944 EKDANIAllELSSSKKKTQDEVAALKREKDRLVQQLKqqtqnRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQIIQPLLE 1023
Cdd:TIGR04523  521 SLKEKIE--KLESEKKEKESKISDLEDELNKDDFELK-----KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ 593

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024339653 1024 LDQNRSKLKLYIghltalchdrdplilrgltppasyhldddraawekELQKMTQEQLRDELEKGEKESAEL 1094
Cdd:TIGR04523  594 KEKEKKDLIKEI-----------------------------------EEKEKKISSLEKELEKAKKENEKL 629
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
553-1094 8.02e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.98  E-value: 8.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  553 ENLQEQLRDKEKQMSSLKDRVKSlqadttnTDTALTTLEEALAEKERTIERLKEQRDRdEREKQEEIDTYKKDIKDLKEk 632
Cdd:PRK03918   165 KNLGEVIKEIKRRIERLEKFIKR-------TENIEELIKEKEKELEEVLREINEISSE-LPELREELEKLEKEVKELEE- 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  633 vgiLQGDLTEKESSLLDLKEHASSLassglkkDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELS------ 706
Cdd:PRK03918   236 ---LKEEIEELEKELESLEGSKRKL-------EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSefyeey 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  707 -DRMQQLEREVTRYREESSkaqaEVDRLLEILKEMENEKNDKDKKIAELERKHASRKlhppyqvsvpapqhvggfvwdfl 785
Cdd:PRK03918   306 lDELREIEKRLSRLEEEIN----GIEERIKELEEKEERLEELKKKLKELEKRLEELE----------------------- 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  786 gnltsRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEealresvQITAEREM 865
Cdd:PRK03918   359 -----ERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK-------KEIKELKK 426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  866 VLAQEESAR-----INAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLA 940
Cdd:PRK03918   427 AIEELKKAKgkcpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLK 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  941 AISEKDANIALLELSSSKK---KTQDEVAALKREKDRLVQQLKQQTQNRMKLMAdnyeddhlkssshsnqtnhkpspdqI 1017
Cdd:PRK03918   507 ELEEKLKKYNLEELEKKAEeyeKLKEKLIKLKGEIKSLKKELEKLEELKKKLAE-------------------------L 561

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024339653 1018 IQPLLELDQNRSKLKLYIGHLTALCHDRDPLILRGLTPPASYHLDDDRAAWEKELQKMTQEQLRDELEKGEKESAEL 1094
Cdd:PRK03918   562 EKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAET 638
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 317-989 9.57e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.89  E-value: 9.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  317 QSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENapdSAKTKALQTVIEMKDSKISSMER 396
Cdd:TIGR00618  188 KKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQS---HAYLTQKREAQEEQLKKQQLLKQ 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  397 GLRDLEEEIQMLKSNGalSTEEREEEMKQMEVYRSHSKFM---KNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQ 473
Cdd:TIGR00618  265 LRARIEELRAQEAVLE--ETQERINRARKAAPLAAHIKAVtqiEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  474 HIEVLKESLTAKEQRAaiLQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIE 553
Cdd:TIGR00618  343 QRRLLQTLHSQEIHIR--DAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFR 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  554 NLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEkv 633
Cdd:TIGR00618  421 DLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLE-- 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  634 giLQGDLTEKESSLLDLKEHASSLASSG------LKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEAR------- 700
Cdd:TIGR00618  499 --LQEEPCPLCGSCIHPNPARQDIDNPGpltrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQqsfsilt 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  701 ----ASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHAS--RKLHPPYQVSVPAP 774
Cdd:TIGR00618  577 qcdnRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQElaLKLTALHALQLTLT 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  775 QHVGGFVWDFLGNLTSR---QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEE 851
Cdd:TIGR00618  657 QERVREHALSIRVLPKEllaSRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAA 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  852 ALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL 931
Cdd:TIGR00618  737 REDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDE 816

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024339653  932 EMKQEALLAAISEKDANIALLELSSSK----KKTQDEVAALKREKDRLVQQLKQQTQNRMKL 989
Cdd:TIGR00618  817 DILNLQCETLVQEEEQFLSRLEEKSATlgeiTHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 515-647 9.82e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 9.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  515 KQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTleEAL 594
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEY--EAL 94

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  595 AEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSL 647
Cdd:COG1579     95 QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL 147
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 350-569 1.01e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 1.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  350 LEQKEKENNMLREEIHR-RFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEV 428
Cdd:COG4942     22 AAEAEAELEQLQQEIAElEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  429 yrshskfMKNKIGQVKQELSRkdtelLALQTKLETLTNQ--FSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK 506
Cdd:COG4942    102 -------QKEELAELLRALYR-----LGRQPPLALLLSPedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  507 ETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSL 569
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
PRK12704 PRK12704
phosphodiesterase; Provisional
 798-936 1.25e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.92  E-value: 1.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  798 KKVANLKHKEqvEKKKSAQMLEEARRREDNLNDS--SQQLQDNLRKKddriEELEEALRESVQITAEREMVLAQEESari 875
Cdd:PRK12704    26 KKIAEAKIKE--AEEEAKRILEEAKKEAEAIKKEalLEAKEEIHKLR----NEFEKELRERRNELQKLEKRLLQKEE--- 96

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024339653  876 NAEKQVEELmmamEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQE 936
Cdd:PRK12704    97 NLDRKLELL----EKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAE 153
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 654-903 1.45e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  654 ASSLASSGLKKDSRLKTLEiALEQKKEECLKMETQLKKAHEATLEARAspELSDRMQQLEREVTRYREESSKAQAEVDRL 733
Cdd:COG4942     12 ALAAAAQADAAAEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLA--ALERRIAALARRIRALEQELAALEAELAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  734 LEILKEMENEKNDKDKKIAELERKHASRKLHPPYQVSvpapqhvggfvwdflgnLTSRQVKDQNKKVANLKHKEQVEKkk 813
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLALL-----------------LSPEDFLDAVRRLQYLKYLAPARR-- 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  814 saQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQ 893
Cdd:COG4942    150 --EQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227

                          250
                   ....*....|
gi 2024339653  894 ELESMKAKLS 903
Cdd:COG4942    228 LIARLEAEAA 237
PTZ00121 PTZ00121
MAEBL; Provisional
 687-988 1.48e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 1.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  687 TQLKK--AHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKLH 764
Cdd:PTZ00121  1082 DAKEDnrADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  765 PPYQVSVPAPQHVGGFVWDFLGNLTSRQVKDQNK-----------KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 833
Cdd:PTZ00121  1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKaedarkaeaarKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  834 QLQDNLRKKDDRIEELEEA-----LRESVQITAER----EMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSS 904
Cdd:PTZ00121  1242 AKKAEEERNNEEIRKFEEArmahfARRQAAIKAEEarkaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  905 TQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQ 984
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAE 1401


                   ....
gi 2024339653  985 NRMK 988
Cdd:PTZ00121  1402 EDKK 1405
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 419-989 1.88e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.94  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  419 REEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLA----LQTKLETLTNQFSDS----------KQHIEVLKESLTA 484
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEeknaLQEQLQAETELCAEAeemrarlaarKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  485 K----EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLR 560
Cdd:pfam01576   83 RleeeEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  561 DKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERT---IERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQ 637
Cdd:pfam01576  163 EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGrqeLEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKE 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  638 GDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEaTLEARASpELSDRMQQLEREvt 717
Cdd:pfam01576  243 EELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE-ELEALKT-ELEDTLDTTAAQ-- 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  718 ryREESSKAQAEVDrllEILKEMENEKNDKDKKIAELERKHASRKlhppyqvsvpapqhvggfvwdflgNLTSRQVKDQN 797
Cdd:pfam01576  319 --QELRSKREQEVT---ELKKALEEETRSHEAQLQEMRQKHTQAL------------------------EELTEQLEQAK 369

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  798 KKVANLKHKEQVEKKKSAQMLEEARrredNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINA 877
Cdd:pfam01576  370 RNKANLEKAKQALESENAELQAELR----TLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESV 445

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  878 EKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRA------ERRKHLEEVLEMKQEALLAAisEKDANIAL 951
Cdd:pfam01576  446 SSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTrlrqleDERNSLQEQLEEEEEAKRNV--ERQLSTLQ 523

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 2024339653  952 LELSSSKKKTQDEVAA----------LKREKDRLVQQLKQQTQNRMKL 989
Cdd:pfam01576  524 AQLSDMKKKLEEDAGTlealeegkkrLQRELEALTQQLEEKAAAYDKL 571
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 704-992 2.09e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 2.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  704 ELSDRMQQLERE---VTRYREESSKAQ-AEVDRLLEILKEMENEKNDKDKKIAELERKHAsrklhppyQVSVPAPQHVGG 779
Cdd:TIGR02169  195 EKRQQLERLRRErekAERYQALLKEKReYEGYELLKEKEALERQKEAIERQLASLEEELE--------KLTEEISELEKR 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  780 FvwdflgNLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRrednlndssqQLQDNLRKKDDRIEELEEalrESVQI 859
Cdd:TIGR02169  267 L------EEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA----------SLERSIAEKERELEDAEE---RLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  860 TAEREMVLAQEEsariNAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAE---RRKHLE----EVLE 932
Cdd:TIGR02169  328 EAEIDKLLAEIE----ELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDElkdYREKLEklkrEINE 403

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  933 MKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMAD 992
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD 463
COG5022 COG5022
Myosin heavy chain [General function prediction only];
228-563 2.24e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.45  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  228 TIQALQDELRIQRDLNQLFQQDSSSRtsepfvAELTEENFQRLHTEHERQakelfllrKTLEEMELRIETQKQTLNARDE 307
Cdd:COG5022    818 CIIKLQKTIKREKKLRETEEVEFSLK------AEVLIQKFGRSLKAKKRF--------SLLKKETIYLQSAQRVELAERQ 883

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  308 SIKKLLEMLQSKGLSAKATEEDhertrrlaeaemhvhhlESLLEQKEKENNMLREEIHRRfenapdSAKTKALQTVIEMK 387
Cdd:COG5022    884 LQELKIDVKSISSLKLVNLELE-----------------SEIIELKKSLSSDLIENLEFK------TELIARLKKLLNNI 940

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  388 DSKI-SSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETL-- 464
Cdd:COG5022    941 DLEEgPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLke 1020

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  465 TNQFSDSKQHIEVLKESLTAKEQRaailQTEVDALRLRLEEKETMLNKKTKQIQeiaeekgtQAGEIHDLKDMLEVKERK 544
Cdd:COG5022   1021 LPVEVAELQSASKIISSESTELSI----LKPLQKLKGLLLLENNQLQARYKALK--------LRRENSLLDDKQLYQLES 1088

                          330
                   ....*....|....*....
gi 2024339653  545 VNVLQKKIENLQEQLRDKE 563
Cdd:COG5022   1089 TENLLKTINVKDLEVTNRN 1107
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 275-981 2.91e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.04  E-value: 2.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  275 ERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKglSAKATEEDHERTRRLAEAEMHVHHLESLLEQKE 354
Cdd:TIGR00606  401 ERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELK--KEILEKKQEELKFVIKELQQLEGSSDRILELDQ 478

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  355 KENNMLREeihrrFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLksngalstEEREEEMKQMEVYRSHSK 434
Cdd:TIGR00606  479 ELRKAERE-----LSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQL--------NHHTTTRTQMEMLTKDKM 545

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  435 FMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKT 514
Cdd:TIGR00606  546 DKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE 625

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  515 KQIQEIAEEKGTQAgEIHDLKDMLEVKERKVNVLQKKI---ENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLE 591
Cdd:TIGR00606  626 DKLFDVCGSQDEES-DLERLKEEIEKSSKQRAMLAGATavySQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKL 704

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  592 EALAEKERTIERLKEQRDRDERE-------KQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLdlkehasslassglKK 664
Cdd:TIGR00606  705 RLAPDKLKSTESELKKKEKRRDEmlglapgRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIE--------------EQ 770

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  665 DSRLKTLeIALEQKKEECLKMETQLKKAHEATLEA-RASPELSDRMQ--QLEREVTRYREESSKAQAEVDRLLEILKEME 741
Cdd:TIGR00606  771 ETLLGTI-MPEEESAKVCLTDVTIMERFQMELKDVeRKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIELNR 849

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  742 NEKNDKDKKIAELERKHASRKLHppyQVSVPAPQHVGGFVWDFLGNLtSRQVKDQNKKVANLKHKE---QVEKKKSAQML 818
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSE---KLQIGTNLQRRQQFEEQLVEL-STEVQSLIREIKDAKEQDsplETFLEKDQQEK 925

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  819 EEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAekQVEELMMAMEKVKQELESM 898
Cdd:TIGR00606  926 EELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNA--QLEECEKHQEKINEDMRLM 1003

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  899 KAKLSSTQQSLAEKETHLTnlraeRRKHLEEVLEMKQEalLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQ 978
Cdd:TIGR00606 1004 RQDIDTQKIQERWLQDNLT-----LRKRENELKEVEEE--LKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGR 1076


                   ...
gi 2024339653  979 LKQ 981
Cdd:TIGR00606 1077 QKG 1079
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 792-986 2.92e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 2.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  792 QVKDQNKKVANLKHKEQVEKKKSAQM---LEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEReMVLA 868
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALqaeLEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGER-ARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  869 QEESARINAE------KQVEELMMAMEKVKQELESMKAKLS---STQQSLAEKETHLTNLRAERRKHLEEvLEMKQEALL 939
Cdd:COG3883     96 YRSGGSVSYLdvllgsESFSDFLDRLSALSKIADADADLLEelkADKAELEAKKAELEAKLAELEALKAE-LEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2024339653  940 AAISEKDANIAllELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNR 986
Cdd:COG3883    175 AQQAEQEALLA--QLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 148-607 3.30e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.11  E-value: 3.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  148 DNTIMDLQTQLKEVLR---------ENDLLRKDVEVKESKLSSSMNSIKT-FWSPELKKERALRKDEASKITIWKEQYRV 217
Cdd:pfam15921  323 ESTVSQLRSELREAKRmyedkieelEKQLVLANSELTEARTERDQFSQESgNLDDQLQKLLADLHKREKELSLEKEQNKR 402

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  218 LQEENQHMQMTIQALQDEL--------RIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLE 289
Cdd:pfam15921  403 LWDRDTGNSITIDHLRRELddrnmevqRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVE 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  290 EMElrieTQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTR-----------RLAEAEMHVHHLESLLE------- 351
Cdd:pfam15921  483 ELT----AKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRsrvdlklqelqHLKNEGDHLRNVQTECEalklqma 558

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  352 QKEKENNMLREEIHRRFENAPDSAKTKALQTViemkdsKISSMERGLRDLEEEIQMLKsngaLSTEEREEEMKQMEVYRS 431
Cdd:pfam15921  559 EKDKVIEILRQQIENMTQLVGQHGRTAGAMQV------EKAQLEKEINDRRLELQEFK----ILKDKKDAKIRELEARVS 628

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  432 HSKFMKNKIGQVKQELSRK----DTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRaaiLQTEVDALRLRLEEKE 507
Cdd:pfam15921  629 DLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEE---METTTNKLKMQLKSAQ 705

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  508 TMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTAL 587
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          490       500
                   ....*....|....*....|
gi 2024339653  588 TTLEEALAEKERTIERLKEQ 607
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEK 805
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 791-981 3.46e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 3.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  791 RQVKDQNKKVANLKHKE---QVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALR------------- 854
Cdd:COG4942     34 QEIAELEKELAALKKEEkalLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEaqkeelaellral 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  855 ---------------ESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 919
Cdd:COG4942    114 yrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEAL 193

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024339653  920 RAERRKhleevlemkqeallaaisekdaniALLELSSSKKKTQDEVAALKREKDRLVQQLKQ 981
Cdd:COG4942    194 KAERQK------------------------LLARLEKELAELAAELAELQQEAEELEALIAR 231
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 507-728 3.56e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 3.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  507 ETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQ------ADT 580
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReelgerARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  581 TNTDTALTTLEEALAEKE------RTIERLKEQRDRDeREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHA 654
Cdd:COG3883     95 LYRSGGSVSYLDVLLGSEsfsdflDRLSALSKIADAD-ADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024339653  655 SSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQA 728
Cdd:COG3883    174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 260-880 3.74e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 44.74  E-value: 3.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  260 AELTEENFQRLhtehERQAKELFLLRKTLEEMELRIETQKQTLNARdesikkllemlqskGLSAKATEEDHERTRR-LAE 338
Cdd:pfam07111   65 AELISRQLQEL----RRLEEEVRLLRETSLQQKMRLEAQAMELDAL--------------AVAEKAGQAEAEGLRAaLAG 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  339 AEMHVHHLESLLEQKEKENNMLREEihrrfenaPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEiqmlksngalstee 418
Cdd:pfam07111  127 AEMVRKNLEEGSQRELEEIQRLHQE--------QLSSLTQAHEEALSSLTSKAEGLEKSLNSLETK-------------- 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  419 REEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKL-ETLTNQFSDSKQHIE--VLKESLTAKEQRAAILQTE 495
Cdd:pfam07111  185 RAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLRKYVgEQVPPEVHSQTWELErqELLDTMQHLQEDRADLQAT 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  496 VDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEI-HDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQmssLKDRVK 574
Cdd:pfam07111  265 VELLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFpKKCRSLLNRWREKVFALMVQLKAQDLEHRDSVKQ---LRGQVA 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  575 SLQADTTNTDTALTTLEEALAEKERTIE--------------RLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDL 640
Cdd:pfam07111  342 ELQEQVTSQSQEQAILQRALQDKAAEVEvermsakglqmelsRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTM 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  641 TEKESSLLDLKEHASSLaSSGLKKDSRLKTL---EIALEQKKEEC---------LKMETQLKKAHEATLEARASPELSDR 708
Cdd:pfam07111  422 TRVEQAVARIPSLSNRL-SYAVRKVHTIKGLmarKVALAQLRQEScpppppappVDADLSLELEQLREERNRLDAELQLS 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  709 MQQLEREVTRYREEsskAQAEVDRLLEILKEMENEKNDKDKKIAELERKhasrklhppYQVSVPAPQHVGGFVWDFLGNL 788
Cdd:pfam07111  501 AHLIQQEVGRAREQ---GEAERQQLSEVAQQLEQELQRAQESLASVGQQ---------LEVARQGQQESTEEAASLRQEL 568

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  789 TSRQV---KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEEL----EEALRESVQITA 861
Cdd:pfam07111  569 TQQQEiygQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELrrlqDEARKEEGQRLA 648

                          650
                   ....*....|....*....
gi 2024339653  862 EREMVLAQEESARINAEKQ 880
Cdd:pfam07111  649 RRVQELERDKNLMLATLQQ 667
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
436-758 4.17e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 4.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  436 MKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTK 515
Cdd:COG4372     43 LQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQK 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  516 QIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRvkSLQADTTNTDTALTTLEEALA 595
Cdd:COG4372    123 ERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEA--EAEQALDELLKEANRNAEKEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  596 EKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIAL 675
Cdd:COG4372    201 ELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  676 EQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELE 755
Cdd:COG4372    281 AALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLS 360


                   ...
gi 2024339653  756 RKH 758
Cdd:COG4372    361 KGA 363
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
489-721 4.35e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 4.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  489 AAILQTEVDA-LRLRLEEKETMLNKKTKQIQEiaeekgtqagEIHDLKDMLEVKERKVNVLQKK--IENLQEQLRDKEKQ 565
Cdd:COG3206    151 AAVANALAEAyLEQNLELRREEARKALEFLEE----------QLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQ 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  566 MSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEqrdrderekQEEIDTYKKDIKDLKEKVGILQGDLTEKES 645
Cdd:COG3206    221 LSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ---------SPVIQQLRAQLAELEAELAELSARYTPNHP 291

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024339653  646 SLLDLKEhasSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAhEATLEARAS--PELSDRMQQLEREVTRYRE 721
Cdd:COG3206    292 DVIALRA---QIAALRAQLQQEAQRILASLEAELEALQAREASLQAQ-LAQLEARLAelPELEAELRRLEREVEVARE 365
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 387-707 4.47e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 44.65  E-value: 4.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  387 KDSKISSMERGLRDLEEEIQMLKS--NGAL-----STEEREEEMKQMEvYRSHSKFMKNKIGQVKQELSRKDTELLALQT 459
Cdd:PTZ00108   997 KEYLLGKLERELARLSNKVRFIKHviNGELvitnaKKKDLVKELKKLG-YVRFKDIIKKKSEKITAEEEEGAEEDDEADD 1075

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  460 KLETLTNQ-------------FSDSKQHIEVLKESLTAKEQRAAILQ---------TEVDALRLRLEEKETMLNKKTKQI 517
Cdd:PTZ00108  1076 EDDEEELGaavsydyllsmpiWSLTKEKVEKLNAELEKKEKELEKLKnttpkdmwlEDLDKFEEALEEQEEVEEKEIAKE 1155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  518 QEIAEEKGTQAGEIHDLKD-MLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAE 596
Cdd:PTZ00108  1156 QRLKSKTKGKASKLRKPKLkKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKP 1235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  597 KERTIERLKEQRDRDEREKQEEIDTYKKDI------KDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKD-SRLK 669
Cdd:PTZ00108  1236 KKSSVKRLKSKKNNSSKSSEDNDEFSSDDLskegkpKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVkKRLE 1315

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 2024339653  670 TLEIALEQKKEECLK---------METQLKKAHEATLEARASPELSD 707
Cdd:PTZ00108  1316 GSLAALKKKKKSEKKtarkkksktRVKQASASQSSRLLRRPRKKKSD 1362
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 149-643 4.78e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.24  E-value: 4.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  149 NTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSpELKKERA--LRKDEASKITIWKEQYRVLQEENQHMQ 226
Cdd:TIGR04523  256 NQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS-DLNNQKEqdWNKELKSELKNQEKKLEEIQNQISQNN 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  227 MTIQALQDEL-RIQRDLNQLFQQDSSSRTsepfvaELTEEN--FQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLN 303
Cdd:TIGR04523  335 KIISQLNEQIsQLKKELTNSESENSEKQR------ELEEKQneIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  304 ARDESIKKLLEMLQS--------KGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENapdsa 375
Cdd:TIGR04523  409 QKDEQIKKLQQEKELlekeierlKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN----- 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  376 kTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEemkqmevYRSHSKFMKNKIGQVKQELSRKDTEL- 454
Cdd:TIGR04523  484 -LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK-------LESEKKEKESKISDLEDELNKDDFELk 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  455 -LALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHD 533
Cdd:TIGR04523  556 kENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  534 LKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLqadttNTDTALTTLEEALAEKERTIERLKEQRDRDER 613
Cdd:TIGR04523  636 IKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDI-----IELMKDWLKELSLHYKKYITRMIRIKDLPKLE 710

                          490       500       510
                   ....*....|....*....|....*....|
gi 2024339653  614 EKQEEIDTYKKDIKDLKEKVGILQGDLTEK 643
Cdd:TIGR04523  711 EKYKEIEKELKKLDEFSKELENIIKNFNKK 740
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
591-738 4.89e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.08  E-value: 4.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  591 EEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEhasslassglkkdsrlkt 670
Cdd:COG2433    387 EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLER------------------ 448

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024339653  671 lEIALEQKKEEclkmetqlkkaheatLEARASPELS---DRMQQLEREVTRYREESSKAQAEVDRLLEILK 738
Cdd:COG2433    449 -ELSEARSEER---------------REIRKDREISrldREIERLERELEEERERIEELKRKLERLKELWK 503
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
398-763 5.01e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 5.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  398 LRDLEEEIQMLKSNGAL---STEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDT--ELLALQTKLETLTNQFSDSK 472
Cdd:COG4717     73 LKELEEELKEAEEKEEEyaeLQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPERLEELE 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  473 QHIEVLKEsltaKEQRAAILQTEVDALRLRLEEKETMLNKKT-KQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKK 551
Cdd:COG4717    153 ERLEELRE----LEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  552 IENLQEQLRDKEKQ-----------------------------MSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIE 602
Cdd:COG4717    229 LEQLENELEAAALEerlkearlllliaaallallglggsllslILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  603 RLKEQRDRDEREKQEEIDTY-------KKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEI-- 673
Cdd:COG4717    309 ALPALEELEEEELEELLAALglppdlsPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElr 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  674 -------ALEQKKEECLKMETQL---KKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMEN- 742
Cdd:COG4717    389 aaleqaeEYQELKEELEELEEQLeelLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEd 468

                          410       420
                   ....*....|....*....|....*....
gi 2024339653  743 --------EKNDKDKKIAELERKHASRKL 763
Cdd:COG4717    469 gelaellqELEELKAELRELAEEWAALKL 497
PRK12704 PRK12704
phosphodiesterase; Provisional
 504-613 5.06e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 5.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  504 EEKETMLNKKTKQIQEIAEEKGTQAG-EIHDLKDMLE--VKERKvnvlqKKIENLQEQLRDKEKQMSSLKDRVKSLQADT 580
Cdd:PRK12704    38 EEAKRILEEAKKEAEAIKKEALLEAKeEIHKLRNEFEkeLRERR-----NELQKLEKRLLQKEENLDRKLELLEKREEEL 112

                           90       100       110
                   ....*....|....*....|....*....|....
gi 2024339653  581 TNTDTALTTLEEALAEKERTIERL-KEQRDRDER 613
Cdd:PRK12704   113 EKKEKELEQKQQELEKKEEELEELiEEQLQELER 146
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 192-754 7.25e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.80  E-value: 7.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  192 PELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQdsssrtsepfvaelteENFQRLH 271
Cdd:TIGR00618  297 AHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQ----------------EIHIRDA 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  272 TEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKglsaKATEEDHERTRRLAEAEMHVHHLESLLE 351
Cdd:TIGR00618  361 HEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQRE----QATIDTRTSAFRDLQGQLAHAKKQQELQ 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  352 QKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRdlEEEIQMLKSNGALSTEEREEEMKQMEVYRS 431
Cdd:TIGR00618  437 QRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQ--ETRKKAVVLARLLELQEEPCPLCGSCIHPN 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  432 HSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLN 511
Cdd:TIGR00618  515 PARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  512 KKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNV---LQKKIENLQEQLRDKEKQMSSLKD--------RVKSLQADT 580
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVrlhLQQCSQELALKLTALHALQLTLTQervrehalSIRVLPKEL 674

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  581 TNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASS 660
Cdd:TIGR00618  675 LASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQART 754

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  661 GLK------------------KDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPE----LSDRMQQLEREVTR 718
Cdd:TIGR00618  755 VLKarteahfnnneevtaalqTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEdilnLQCETLVQEEEQFL 834

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 2024339653  719 YR-EESSKAQAEVDRLLEILKEMENEKNDKDKKIAEL 754
Cdd:TIGR00618  835 SRlEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKI 871
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 549-897 7.38e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.57  E-value: 7.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  549 QKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLK-EQRDRD-EREKQEEIDTYKKDI 626
Cdd:pfam17380  298 QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRqEERKRElERIRQEEIAMEISRM 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  627 KDLKEkvgiLQGDLTEKESSLLDLKEHASslassglkkdsRLKTLEIALEQKKEECLKMETQLKKAHEatlEARASpELS 706
Cdd:pfam17380  378 RELER----LQMERQQKNERVRQELEAAR-----------KVKILEEERQRKIQQQKVEMEQIRAEQE---EARQR-EVR 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  707 DRMQQLEREVTRYREESSKAQAEVDRLleilkemENEKNDKDKKIAELERKHASRKLhppyqvsvpapqhvggfvwdflg 786
Cdd:pfam17380  439 RLEEERAREMERVRLEEQERQQQVERL-------RQQEEERKRKKLELEKEKRDRKR----------------------- 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  787 nltsrqVKDQNKKVAnlkhkEQVEKKKSAQMLEEARRREdnLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAER--- 863
Cdd:pfam17380  489 ------AEEQRRKIL-----EKELEERKQAMIEEERKRK--LLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRriq 555

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 2024339653  864 -EMVLAQEESARINAEKQVEELMMAM---EKVKQELES 897
Cdd:pfam17380  556 eQMRKATEERSRLEAMEREREMMRQIvesEKARAEYEA 593
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
502-944 7.48e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 7.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  502 RLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKE--RKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQAD 579
Cdd:COG4717     89 EYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEEL 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  580 TTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEH------ 653
Cdd:COG4717    169 EAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEerlkea 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  654 ----------ASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREES 723
Cdd:COG4717    249 rlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL 328

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  724 SKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKLHPPYQVsvpapqhvggfvwdflgNLTSRQVKDQNKKVANL 803
Cdd:COG4717    329 GLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAA-----------------LLAEAGVEDEEELRAAL 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  804 KHKEQVEKKKSAqmLEEARRREDNLNDSSQQLQDNLRKKD--DRIEELEEALREsvqitAEREMVLAQEESARINAEKQV 881
Cdd:COG4717    392 EQAEEYQELKEE--LEELEEQLEELLGELEELLEALDEEEleEELEELEEELEE-----LEEELEELREELAELEAELEQ 464

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  882 EELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEvlemKQEALLAAISE 944
Cdd:COG4717    465 LEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE----RLPPVLERASE 523
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
825-995 7.83e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 7.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  825 EDNLNDSSQQLQDNLRKKDDRIEELEEALREsvqitAEREMVLAQEESARINAEKQVEELMmamekvkQELESMKAKLSS 904
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEE-----AEAALEEFRQKNGLVDLSEEAKLLL-------QQLSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  905 TQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK--DANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQ 982
Cdd:COG3206    231 ARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQlaELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310

                          170
                   ....*....|...
gi 2024339653  983 TQNRMKLMADNYE 995
Cdd:COG3206    311 AQRILASLEAELE 323
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 392-604 8.10e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 43.35  E-value: 8.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  392 SSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDS 471
Cdd:pfam07888   34 NRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEEL 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  472 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKK 551
Cdd:pfam07888  114 SEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKE 193

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  552 IENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERL 604
Cdd:pfam07888  194 FQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERL 246
PRK01156 PRK01156
chromosome segregation protein; Provisional
 440-909 8.29e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 43.74  E-value: 8.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  440 IGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDalrlRLEEKETMLNKKTKQIQE 519
Cdd:PRK01156   185 IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALN----ELSSLEDMKNRYESEIKT 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  520 IAEEKGTQAGEIHDLKDMLEVKERKVN--VLQKKIE-----NLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEE 592
Cdd:PRK01156   261 AESDLSMELEKNNYYKELEERHMKIINdpVYKNRNYindyfKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYND 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  593 ALaEKERTIERLKEQRDrDEREKQEEIDTYKKDIKDLKEKV---GILQGDLTEKESSLLDLKE-HASSLASSGLKKDSRL 668
Cdd:PRK01156   341 YI-KKKSRYDDLNNQIL-ELEGYEMDYNSYLKSIESLKKKIeeySKNIERMSAFISEILKIQEiDPDAIKKELNEINVKL 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  669 KTLEI---ALEQKKEECLKMETQLKKAHEATLEARASPELSDRM--QQLEREVTRYREESSKAQAEVDRLLEILKEMENE 743
Cdd:PRK01156   419 QDISSkvsSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLgeEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEK 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  744 KNDKDKKIAELERKHASRKLHPPYQVSvpapqhvggfvwDFLGNLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARR 823
Cdd:PRK01156   499 IVDLKKRKEYLESEEINKSINEYNKIE------------SARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  824 REDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLS 903
Cdd:PRK01156   567 RTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIE 646


                   ....*.
gi 2024339653  904 STQQSL 909
Cdd:PRK01156   647 KLRGKI 652
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
697-935 8.51e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 8.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  697 LEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEIlkemeNEKNDK-DKKIAELERKHASRKLHPPYQVSvpapq 775
Cdd:COG4913    218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPI-----RELAERyAAARERLAELEYLRAALRLWFAQ----- 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  776 hvggfvwdflgnltsRQVKDQNKKVANLKHkeqvEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKD-DRIEELEEALR 854
Cdd:COG4913    288 ---------------RRLELLEAELEELRA----ELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  855 ESVQITAEREMVLAQ-EESAR---INAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEV 930
Cdd:COG4913    349 RLERELEERERRRARlEALLAalgLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEI 428


                   ....*
gi 2024339653  931 LEMKQ 935
Cdd:COG4913    429 ASLER 433
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 808-944 8.51e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 8.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  808 QVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEAL------RESVQITAEremvLAQEESARINAEKQV 881
Cdd:COG1579     37 EDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLgnvrnnKEYEALQKE----IESLKRRISDLEDEI 112

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  882 EELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEmKQEALLAAISE 944
Cdd:COG1579    113 LELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA-EREELAAKIPP 174
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
518-662 8.88e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.31  E-value: 8.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  518 QEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQlrdkekqmsslkdrVKSLqadttntdtalttlEEALAEK 597
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAE--------------VEEL--------------EAELEEK 439

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024339653  598 ERTIERLKE------QRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGL 662
Cdd:COG2433    440 DERIERLERelsearSEERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGEL 510
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 362-1004 1.22e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  362 EEIHRRFENAPDSAKTKalQTVIEMKDSKISSMERGLRDLEE-EIQMLKSNGALsteereeEMKQMEVYRSHSKFMKNKI 440
Cdd:TIGR00606  237 REIVKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALKSrKKQMEKDNSEL-------ELKMEKVFQGTDEQLNDLY 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  441 GQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEI 520
Cdd:TIGR00606  308 HNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPF 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  521 AEekgTQAGEIHDLKdmLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERT 600
Cdd:TIGR00606  388 SE---RQIKNFHTLV--IERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKE 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  601 IERLKEQRDR----DEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLL-DLKEHASSLASSGLKKDSRLKTLEIAl 675
Cdd:TIGR00606  463 LQQLEGSSDRilelDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDrKLRKLDQEMEQLNHHTTTRTQMEMLT- 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  676 eQKKEECLKMETQLKKAHEATLEARA-----SPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKK 750
Cdd:TIGR00606  542 -KDKMDKDEQIRKIKSRHSDELTSLLgyfpnKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQ 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  751 IAELERKHASRKLHPPYQVSvpapqhvggfvwdfLGNLTSRqVKDQNKKVANLKHKEQVEKKKSAQMLEEAR-------- 822
Cdd:TIGR00606  621 LSSYEDKLFDVCGSQDEESD--------------LERLKEE-IEKSSKQRAMLAGATAVYSQFITQLTDENQsccpvcqr 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  823 --RREDNLNDSSQQLQDNLRKKDDRIEELEEALResvQITAEREMVLAQEESARINAEKQVEELmmamEKVKQELESMKA 900
Cdd:TIGR00606  686 vfQTEAELQEFISDLQSKLRLAPDKLKSTESELK---KKEKRRDEMLGLAPGRQSIIDLKEKEI----PELRNKLQKVNR 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  901 KLSSTQQSLAEKETHLTNLRAERRKH---LEEVLEMKQ-EALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLV 976
Cdd:TIGR00606  759 DIQRLKNDIEEQETLLGTIMPEEESAkvcLTDVTIMERfQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHEL 838

                          650       660
                   ....*....|....*....|....*....
gi 2024339653  977 QQLKQQTQNRMKLMAD-NYEDDHLKSSSH 1004
Cdd:TIGR00606  839 DTVVSKIELNRKLIQDqQEQIQHLKSKTN 867
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 474-744 1.29e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  474 HIEVLKESLTAKEQRAAI-LQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAgeIHDLKDMLEVKERKVNVLQKKI 552
Cdd:PRK05771    32 HIEDLKEELSNERLRKLRsLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEEL--IKDVEEELEKIEKEIKELEEEI 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  553 ENLQEQLRDKEKQMSSLKdRVKSLqadttntdtalTTLEEALAEKERTIERLKE-QRDRDEREKQEEIDTYKKDIKDLKE 631
Cdd:PRK05771   110 SELENEIKELEQEIERLE-PWGNF-----------DLDLSLLLGFKYVSVFVGTvPEDKLEELKLESDVENVEYISTDKG 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  632 KVGILQgdLTEKEssllDLKEHASSLASSGLKKD--SRLKTLEIALEQKKEECLKMETQLKKAHEatlearaspELSDRM 709
Cdd:PRK05771   178 YVYVVV--VVLKE----LSDEVEEELKKLGFERLelEEEGTPSELIREIKEELEEIEKERESLLE---------ELKELA 242

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024339653  710 QQLEREVTRYRE----ESSKAQA--------------------EVDRLLEILKEMENEK 744
Cdd:PRK05771   243 KKYLEELLALYEyleiELERAEAlskflktdktfaiegwvpedRVKKLKELIDKATGGS 301
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 277-528 1.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  277 QAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQskglsakateedhERTRRLAEAEMHVHHLESLLEQKEKE 356
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-------------ALERRIAALARRIRALEQELAALEAE 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  357 NNMLREEIhrrfenapdsaktKALQTVIEMKDSKISSMergLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFM 436
Cdd:COG4942     85 LAELEKEI-------------AELRAELEAQKEELAEL---LRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPAR 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  437 KNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQ 516
Cdd:COG4942    149 REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228

                          250
                   ....*....|..
gi 2024339653  517 IQEIAEEKGTQA 528
Cdd:COG4942    229 IARLEAEAAAAA 240
PRK01156 PRK01156
chromosome segregation protein; Provisional
 470-745 1.87e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.58  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  470 DSKQHIEVLKESLTAK--EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKER---K 544
Cdd:PRK01156   147 DPAQRKKILDEILEINslERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERlsiE 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  545 VNVLQKKIENLQEQLrdkeKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKK 624
Cdd:PRK01156   227 YNNAMDDYNNLKSAL----NELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFK 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  625 DIKDLKEKVGILQG-----------------------DLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEE 681
Cdd:PRK01156   303 YKNDIENKKQILSNidaeinkyhaiikklsvlqkdynDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEY 382

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024339653  682 CLKMETQLKKAHEATLEARASPE-LSDRMQQLEREVTRYREESSKAQAEVDRLLEilKEMENEKN 745
Cdd:PRK01156   383 SKNIERMSAFISEILKIQEIDPDaIKKELNEINVKLQDISSKVSSLNQRIRALRE--NLDELSRN 445
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 591-841 2.16e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 2.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  591 EEALAEKERTIERLKEQRDRDEREK---QEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEhasslassglkkdsR 667
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEkalLKQLAALERRIAALARRIRALEQELAALEAELAELEK--------------E 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  668 LKTLEIALEQKKEECLKMETQLKKAHEAT----LEARASPELSDRMQQLEREVTRYREESSKA-QAEVDRLLEILKEMEN 742
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPplalLLSPEDFLDAVRRLQYLKYLAPARREQAEElRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  743 EKNDKDKKIAELERKHASrklhppyqvsvpapqhvggfvwdflgnlTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEAR 822
Cdd:COG4942    172 ERAELEALLAELEEERAA----------------------------LEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                          250
                   ....*....|....*....
gi 2024339653  823 RREDNLNDSSQQLQDNLRK 841
Cdd:COG4942    224 ELEALIARLEAEAAAAAER 242
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 482-882 2.45e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.27  E-value: 2.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  482 LTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRD 561
Cdd:pfam02463  148 AMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLL 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  562 KEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILqgdLT 641
Cdd:pfam02463  228 YLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEL---LK 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  642 EKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYRE 721
Cdd:pfam02463  305 LERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESE 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  722 ESSKAQAEVDRLLEILKEMENEKNDKD-----KKIAELERKHASRKLHPPYQVSVPAPQHVGGFVWDFLGNLTSRQVKD- 795
Cdd:pfam02463  385 RLSSAAKLKEEELELKSEEEKEAQLLLelarqLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDe 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  796 -QNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESAR 874
Cdd:pfam02463  465 lELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVA 544


                   ....*...
gi 2024339653  875 INAEKQVE 882
Cdd:pfam02463  545 ISTAVIVE 552
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
439-625 2.58e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 2.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  439 KIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKEsltakEQRAAILQTEVDALRLRLEEketmLNKKTKQIQ 518
Cdd:COG4913    618 ELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWD-----EIDVASAEREIAELEAELER----LDASSDDLA 688

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  519 EIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEK- 597
Cdd:COG4913    689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELr 768

                          170       180       190
                   ....*....|....*....|....*....|.
gi 2024339653  598 ---ERTIERLKEQRDRDEREKQEEIDTYKKD 625
Cdd:COG4913    769 enlEERIDALRARLNRAEEELERAMRAFNRE 799
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 530-763 2.97e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.84  E-value: 2.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  530 EIHDLkDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQ-ADTTNTDTALTTLEEALAEKERTIERLkeqr 608
Cdd:PRK05771    24 ALHEL-GVVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNpLREEKKKVSVKSLEELIKDVEEELEKI---- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  609 DRDEREKQEEIDTYKKDIKDLKEKVGILQ--GDLTEKESSLLDLKehaSSLASSGLKKDSRLKTLEIALEQKKEECLKmE 686
Cdd:PRK05771    99 EKEIKELEEEISELENEIKELEQEIERLEpwGNFDLDLSLLLGFK---YVSVFVGTVPEDKLEELKLESDVENVEYIS-T 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024339653  687 TQLKKAHEATLEARASPELSDRMQQLEreVTRYR-EESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKHASRKL 763
Cdd:PRK05771   175 DKGYVYVVVVVLKELSDEVEEELKKLG--FERLElEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELL 250
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 591-762 3.11e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  591 EEALAEKERTIERLKEQRDRDERE---KQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSR 667
Cdd:COG3883     22 QKELSELQAELEAAQAELDALQAEleeLNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGS 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  668 LKTLEIALEQKK-EECLKMETQLKKAHEATLEARAspELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKND 746
Cdd:COG3883    102 VSYLDVLLGSESfSDFLDRLSALSKIADADADLLE--ELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAE 179

                          170
                   ....*....|....*.
gi 2024339653  747 KDKKIAELERKHASRK 762
Cdd:COG3883    180 QEALLAQLSAEEAAAE 195
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
391-578 3.13e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 3.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  391 ISSMERGLRDLEEEIQML----KSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTN 466
Cdd:COG4913    237 LERAHEALEDAREQIELLepirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  467 QFSDSKQHIEVLKESL-TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDL----KDMLEVK 541
Cdd:COG4913    317 RLDALREELDELEAQIrGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALraeaAALLEAL 396

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2024339653  542 ERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQA 578
Cdd:COG4913    397 EEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 194-738 3.22e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.65  E-value: 3.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  194 LKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTE 273
Cdd:pfam05557   54 QKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSE 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  274 HERQAKELFLLRKTLEEMELRI---ETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLL 350
Cdd:pfam05557  134 LEELQERLDLLKAKASEAEQLRqnlEKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLREHN 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  351 EQ--KEKENN-MLREEIHRRFENAPDSAKTKALQTVIEMKDSKissMERGLRDLEEEIQMLKSNgALSTEEREEEMKQME 427
Cdd:pfam05557  214 KHlnENIENKlLLKEEVEDLKRKLEREEKYREEAATLELEKEK---LEQELQSWVKLAQDTGLN-LRSPEDLSRRIEQLQ 289

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  428 vyrSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE--E 505
Cdd:pfam05557  290 ---QREIVLKEENSSLTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILEsyD 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  506 KETMLNKKTKQIQEIAEEkgtqageihdLKDMlevkerkVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDT 585
Cdd:pfam05557  367 KELTMSNYSPQLLERIEE----------AEDM-------TQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQ 429

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  586 ALTTLEEALAEKERTIERLKEQRDRDEREKQEEidtyKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKD 665
Cdd:pfam05557  430 QESLADPSYSKEEVDSLRRKLETLELERQRLRE----QKNELEMELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQ 505

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  666 srlktleiaLEQKKEECLKMETQLKKAHEATLEARASPELSDRMQqlEREVTRYREESSKAQAEVDRLLEILK 738
Cdd:pfam05557  506 ---------LEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMN--FKEVLDLRKELESAELKNQRLKEVFQ 567
Mrs2_Mfm1p-like cd12823
Saccharomyces cerevisiae inner mitochondrial membrane Mg2+ transporters Mfm1p and Mrs2p-like ...
 451-563 3.29e-03

Saccharomyces cerevisiae inner mitochondrial membrane Mg2+ transporters Mfm1p and Mrs2p-like family; A eukaryotic subfamily belonging to the Escherichia coli CorA-Salmonella typhimurium ZntB_like family (EcCorA_ZntB-like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This functionally diverse subfamily includes the inner mitochondrial membrane Mg2+ transporters Saccharomyces cerevisiae Mfm1p/Lpe10p, Mrs2p, and human MRS2/ MRS2L. It also includes a family of Arabidopsis thaliana proteins (AtMGTs) some of which are localized to distinct tissues, and not all of which can transport Mg2+. Structures of the intracellular domain of two EcCorA_ZntB-like family transporters: Vibrio parahaemolyticus and Salmonella typhimurium ZntB form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA, and Mrs2p. Natural variants such as GVN and GIN, as in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.


Pssm-ID: 213357  Cd Length: 323  Bit Score: 41.08  E-value: 3.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  451 DTELLALQTK----LETLTNQFSDSK-QHIEVLKESLTAKEQRAAILQTEVDALrlrLEEKETM--LNKKTKQIQEIAEE 523
Cdd:cd12823    127 EAELKRLEPEalplLDELTDKISTSNlERLLPLKRRLVELETRVQKVRDALEEL---LDDDEDMadMYLTDKAAGPERLE 203

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 2024339653  524 KGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKE 563
Cdd:cd12823    204 SSRKEDDHEEVEMLLEAYLQQVDELLNKLEELREYIDDTE 243
46 PHA02562
endonuclease subunit; Provisional
 209-421 3.68e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 3.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  209 TIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLnqlfqQDSSSRTSEPFVAELTE------ENFQRLHTEHERQAKELF 282
Cdd:PHA02562   170 KLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKN-----IEEQRKKNGENIARKQNkydelvEEAKTIKAEIEELTDELL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  283 LLRKTLEEME---LRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNM 359
Cdd:PHA02562   245 NLVMDIEDPSaalNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDE 324

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024339653  360 LREEIHRRFENapdSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREE 421
Cdd:PHA02562   325 LEEIMDEFNEQ---SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAK 383
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
810-982 4.08e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  810 EKKKSAQMLEEARRREDNLNDSSQQLQDnLRKKDDRIEELEEALRESVQITAEREMVLAQEESARI-NAEKQVEELMMAM 888
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALED-AREQIELLEPIRELAERYAAARERLAELEYLRAALRLwFAQRRLELLEAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  889 EKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKH---LEEVLEMKQEALLAAISEKDANIALLE-----LSSSKKK 960
Cdd:COG4913    298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNggdRLEQLEREIERLERELEERERRRARLEallaaLGLPLPA 377

                          170       180
                   ....*....|....*....|..
gi 2024339653  961 TQDEVAALKREKDRLVQQLKQQ 982
Cdd:COG4913    378 SAEEFAALRAEAAALLEALEEE 399
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
375-577 4.09e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 4.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  375 AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKS-NGALSTEEReeemkqmevyrshSKFMKNKIGQVKQELSRKDTE 453
Cdd:COG3206    168 LRREEARKALEFLEEQLPELRKELEEAEAALEEFRQkNGLVDLSEE-------------AKLLLQQLSELESQLAEARAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  454 LLALQTKLETLTNQFSDSKQHIEVLKES--LTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEI 531
Cdd:COG3206    235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI 314

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2024339653  532 -HDLKDMLEVKERKVNVLQKKIEnlqeQLRDKEKQMSSLKDRVKSLQ 577
Cdd:COG3206    315 lASLEAELEALQAREASLQAQLA----QLEARLAELPELEAELRRLE 357
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
273-728 4.56e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 4.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  273 EHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGL---SAKATEEDHERTRRLAEAEMHVHHLESL 349
Cdd:COG4717     82 EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqeLEALEAELAELPERLEELEERLEELREL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  350 LEQKEKennmLREEIHRRFEnapdsAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVY 429
Cdd:COG4717    162 EEELEE----LEAELAELQE-----ELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  430 RShskfmKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKesltakeqRAAILQTEVDALRLRLEEKETM 509
Cdd:COG4717    233 EN-----ELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAG--------VLFLVLGLLALLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  510 LNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKslqadttntdtaltt 589
Cdd:COG4717    300 LGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--------------- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  590 leeaLAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASslaSSGLKKdsRLK 669
Cdd:COG4717    365 ----LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD---EEELEE--ELE 435

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024339653  670 TLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQA 728
Cdd:COG4717    436 ELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAA 494
PRK12704 PRK12704
phosphodiesterase; Provisional
 792-902 4.58e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.92  E-value: 4.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  792 QVKDQNKKVANLKHKEQVEKKKSAQMLEEA-RRREDNLNDSSQqlqdNLRKKDDRIEELEEalresvQITAEREMVLAQE 870
Cdd:PRK12704    61 EAKEEIHKLRNEFEKELRERRNELQKLEKRlLQKEENLDRKLE----LLEKREEELEKKEK------ELEQKQQELEKKE 130

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2024339653  871 ESARINAEKQVEEL------------MMAMEKVKQELESMKAKL 902
Cdd:PRK12704   131 EELEELIEEQLQELerisgltaeeakEILLEKVEEEARHEAAVL 174
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 536-755 5.19e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 5.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  536 DMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREK 615
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  616 QEEIDTYK--------KDIKDLKEKVGILQgDLTEKESSLLDlkehasslassglkkdsRLKTLEIALEQKKEECLKMET 687
Cdd:COG3883     96 YRSGGSVSyldvllgsESFSDFLDRLSALS-KIADADADLLE-----------------ELKADKAELEAKKAELEAKLA 157

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024339653  688 QLKKAHEatlearaspELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELE 755
Cdd:COG3883    158 ELEALKA---------ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
PRK08475 PRK08475
F0F1 ATP synthase subunit B; Validated
 925-996 5.35e-03

F0F1 ATP synthase subunit B; Validated


Pssm-ID: 236272 [Multi-domain]  Cd Length: 167  Bit Score: 38.84  E-value: 5.35e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024339653  925 KHLEEVlemkQEALLAAISEKDAniALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNYED 996
Cdd:PRK08475    60 KRLEEI----QEKLKESKEKKED--ALKKLEEAKEKAELIVETAKKEAYILTQKIEKQTKDDIENLIKSFEE 125
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
806-986 5.62e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 5.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  806 KEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALREsvqitAEREmvLAQEESARINA-EKQVEEL 884
Cdd:COG4913    278 RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDE-----LEAQ--IRGNGGDRLEQlEREIERL 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  885 MMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVlemkqEALLAAISEKDAniallelssskkKTQDE 964
Cdd:COG4913    351 ERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEAL-----EEELEALEEALA------------EAEAA 413

                          170       180
                   ....*....|....*....|..
gi 2024339653  965 VAALKREKDRLVQQLKQQTQNR 986
Cdd:COG4913    414 LRDLRRELRELEAEIASLERRK 435
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 344-909 5.69e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.19  E-value: 5.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  344 HHLESLLEQKEKENNMLRE----------------------EIHRRFEN-APDSAKTKALQTVIEMKDSKISSMERGLRD 400
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEikaqindledvadkaisnddpeEIEKKIENiVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS 1208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  401 LEE----EIQMLKSNGALSTEEREEEMKQME-VYRSHSKFMKN--KIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQ 473
Cdd:TIGR01612 1209 LEEvkgiNLSYGKNLGKLFLEKIDEEKKKSEhMIKAMEAYIEDldEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKD 1288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  474 HievlkeSLTAKEQRAAILQTEVDALRLRLE-EKETMLNKKTKQIQEIAEEKGTQAGEIH----------------DLKD 536
Cdd:TIGR01612 1289 H------HIISKKHDENISDIREKSLKIIEDfSEESDINDIKKELQKNLLDAQKHNSDINlylneianiynilklnKIKK 1362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  537 MLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKslqadttnTDTALTTLEEALAEKE--RTIERLKEQRDRDERE 614
Cdd:TIGR01612 1363 IIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN--------LEECKSKIESTLDDKDidECIKKIKELKNHILSE 1434

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  615 kQEEIDTYKKDIKDLKEKVGILQGDL-------------------TEKESSLLDLKEHASSLASSGLKKDSRLKTLE--- 672
Cdd:TIGR01612 1435 -ESNIDTYFKNADENNENVLLLFKNIemadnksqhilkikkdnatNDHDFNINELKEHIDKSKGCKDEADKNAKAIEknk 1513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  673 IALEQKKEECLKMetqLKKAHEATLEARASPELSDRmQQLEREVtryREESSKAQAEVDRLLEILKEMENEKNDKDKKIA 752
Cdd:TIGR01612 1514 ELFEQYKKDVTEL---LNKYSALAIKNKFAKTKKDS-EIIIKEI---KDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAA 1586

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  753 eleRKHASRKLHPPYQVSVPapqhvggfvwdflgNLTSRQVKDQN-KKVAN--LKHKEQVEKKKSAQMLEEARRREDNLN 829
Cdd:TIGR01612 1587 ---KNDKSNKAAIDIQLSLE--------------NFENKFLKISDiKKKINdcLKETESIEKKISSFSIDSQDTELKENG 1649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  830 DSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKV-KQELESMKAKLSSTQQS 908
Cdd:TIGR01612 1650 DNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIAnKEEIESIKELIEPTIEN 1729


                   .
gi 2024339653  909 L 909
Cdd:TIGR01612 1730 L 1730
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
486-979 5.92e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 5.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  486 EQRAAILQTEVDALR------LRLEEKETMLnkktKQIQEIAEE---KGTQAGEIHDLKDMLEV--KERKVNVLQKKIEN 554
Cdd:COG4913    224 FEAADALVEHFDDLErahealEDAREQIELL----EPIRELAERyaaARERLAELEYLRAALRLwfAQRRLELLEAELEE 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  555 LQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLE-EALAEKERTIERLKEQRDRdereKQEEIDTYKKDIKDLKekv 633
Cdd:COG4913    300 LRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEE----RERRRARLEALLAALG--- 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  634 giLQGDLTEKEssLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEAtLEARASPeLSDRMQQLE 713
Cdd:COG4913    373 --LPLPASAEE--FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS-LERRKSN-IPARLLALR 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  714 REVtryREESSKAQAEVD---RLLEILKEMEN------------------EKNDKDKKIAELERKHASRKLH-------- 764
Cdd:COG4913    447 DAL---AEALGLDEAELPfvgELIEVRPEEERwrgaiervlggfaltllvPPEHYAAALRWVNRLHLRGRLVyervrtgl 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  765 PPYQVSVPAPQHV-----------GGFVWDFLGNLTSRQvkdqnkKVANLKHKEQVEKK--KSAQMLEEARRREDNLNDS 831
Cdd:COG4913    524 PDPERPRLDPDSLagkldfkphpfRAWLEAELGRRFDYV------CVDSPEELRRHPRAitRAGQVKGNGTRHEKDDRRR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  832 SQQL----QDNLRKKDDRIEELEEalresvqitAEREMVLAQEESARINAE-KQVEELMMAMEKVkQELESMKAKLSSTQ 906
Cdd:COG4913    598 IRSRyvlgFDNRAKLAALEAELAE---------LEEELAEAEERLEALEAElDALQERREALQRL-AEYSWDEIDVASAE 667

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  907 QSLAEKETHLTNLRAERrkhlEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQL 979
Cdd:COG4913    668 REIAELEAELERLDASS----DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRL 736
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 141-544 7.50e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 40.73  E-value: 7.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  141 HSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKtfwSPELKKERALRKDEASKITIWKEQYRVLQE 220
Cdd:pfam02463  618 DDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV---KASLSELTKELLEIQELQEKAESELAKEEI 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  221 ENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQ 300
Cdd:pfam02463  695 LRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEK 774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  301 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKAL 380
Cdd:pfam02463  775 ELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE 854

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  381 QTVIEMKDS--KISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQ 458
Cdd:pfam02463  855 ELERLEEEItkEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE 934

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  459 TKLETLTNQFSDSKQ----HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDL 534
Cdd:pfam02463  935 EEPEELLLEEADEKEkeenNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014

                          410
                   ....*....|
gi 2024339653  535 KDMLEVKERK 544
Cdd:pfam02463 1015 TCQRLKEFLE 1024
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
545-984 8.46e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 40.41  E-value: 8.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  545 VNVLQKKIENLQEQLRDK--EKQMSSLKDRVKSLQADTTNTDTALTTLEEalaEKERTIERLKEQRDRDE--REKQEEID 620
Cdd:PRK02224   178 VERVLSDQRGSLDQLKAQieEKEEKDLHERLNGLESELAELDEEIERYEE---QREQARETRDEADEVLEehEERREELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  621 TYKKDIKDLKEKVgilqgdlTEKESSLLDLKEHASSLassglkkDSRLKTLEIALEQKKEEClkmetQLKKAHEATLEAR 700
Cdd:PRK02224   255 TLEAEIEDLRETI-------AETEREREELAEEVRDL-------RERLEELEEERDDLLAEA-----GLDDADAEAVEAR 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  701 ASpELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERKhasrklhppyqvsvpapqhvggf 780
Cdd:PRK02224   316 RE-ELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE----------------------- 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  781 vwdflgnltsrqvkdqnkkvanlkhkeqvekkksaqmLEEARrrednlndssqqlqDNLRKKDDRIEELEEALREsvqit 860
Cdd:PRK02224   372 -------------------------------------LEEAR--------------EAVEDRREEIEELEEEIEE----- 395

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  861 aeremvlaqeesarinAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRaERRKHLEEVLE-------- 932
Cdd:PRK02224   396 ----------------LRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR-ERVEEAEALLEagkcpecg 458

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024339653  933 --MKQEALLAAISEKDANIAllELSSSKKKTQDEVAALKREKDRLVQQLKQQTQ 984
Cdd:PRK02224   459 qpVEGSPHVETIEEDRERVE--ELEAELEDLEEEVEEVEERLERAEDLVEAEDR 510
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
212-729 8.81e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.28  E-value: 8.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  212 KEQYRVLQEENQHMQmTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELT--EENFQRLHTEHERQAKELFLLR---- 285
Cdd:COG4913    248 REQIELLEPIRELAE-RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEelRAELARLEAELERLEARLDALReeld 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  286 -----------KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAemhvhHLESlLEQKE 354
Cdd:COG4913    327 eleaqirgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA-----LLEA-LEEEL 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  355 KENNMLREEIHRRFENApdSAKTKALQTVIEMKDSKISSMERGLRDLEEEIqmlksNGALSTEERE-------------E 421
Cdd:COG4913    401 EALEEALAEAEAALRDL--RRELRELEAEIASLERRKSNIPARLLALRDAL-----AEALGLDEAElpfvgelievrpeE 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  422 EMKQM------------------------EVYRSHSKFMKNKIGQVKQELSRKDTELL---ALQTKLETLTNQFSDSkqh 474
Cdd:COG4913    474 ERWRGaiervlggfaltllvppehyaaalRWVNRLHLRGRLVYERVRTGLPDPERPRLdpdSLAGKLDFKPHPFRAW--- 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  475 ievLKESLtakEQRAAILQTE-VDALRlrleeketmlnkktkqiqeiAEEKG-TQAGEIHDLKDMLEVK----------- 541
Cdd:COG4913    551 ---LEAEL---GRRFDYVCVDsPEELR--------------------RHPRAiTRAGQVKGNGTRHEKDdrrrirsryvl 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  542 ----ERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEAL--AEKERTIERLKEQRDR----- 610
Cdd:COG4913    605 gfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERldass 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  611 -DEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLassglkkDSRLKTLEIALEQKKEECLkmETQL 689
Cdd:COG4913    685 dDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL-------QDRLEAAEDLARLELRALL--EERF 755

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 2024339653  690 KKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAE 729
Cdd:COG4913    756 AAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK11091 PRK11091
aerobic respiration control sensor protein ArcB; Provisional
 818-880 9.12e-03

aerobic respiration control sensor protein ArcB; Provisional


Pssm-ID: 236842 [Multi-domain]  Cd Length: 779  Bit Score: 40.31  E-value: 9.12e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024339653  818 LEEARRREDNLNdssQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQ 880
Cdd:PRK11091    94 LEEMRERDLELN---VQLKDNIAQLNQEIAEREKAEEARQEAFEQLKNEIKEREETQIELEQQ 153
PTZ00491 PTZ00491
major vault protein; Provisional
 833-942 9.61e-03

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 40.00  E-value: 9.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024339653  833 QQLQDNLRKKDDRIEELE-EALRESVQITAE-REMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLA 910
Cdd:PTZ00491   686 QKMHDKAKAEEQRTKLLElQAESAAVESSGQsRAEALAEAEARLIEAEAEVEQAELRAKALRIEAEAELEKLRKRQELEL 765

                           90       100       110
                   ....*....|....*....|....*....|..
gi 2024339653  911 EKETHLTNLRAERRKHLEEVLEMKQEALLAAI 942
Cdd:PTZ00491   766 EYEQAQNELEIAKAKELADIEATKFERIVEAL 797
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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