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Conserved domains on  [gi|2024432123|ref|XP_040511772|]
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synphilin-1 isoform X1 [Gallus gallus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
317-504 5.23e-23

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 100.41  E-value: 5.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 317 ILNIVKEGQISLLPHLAADNLDKIHDECDNNLLHVAASKGHAECLQHLTSLmGEDcLNERNIEQLTPAGLAIKNGQLECV 396
Cdd:COG0666    59 LAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEA-GAD-VNARDKDGETPLHLAAYNGNLEIV 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 397 RWMVsetEAIAEL-SCSKDHPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNTAVHIAAQHGYLGCIQTLVEYG 475
Cdd:COG0666   137 KLLL---EAGADVnAQDNDGNTPLHLAAANGNLEIVKLLL----EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209

                         170       180
                  ....*....|....*....|....*....
gi 2024432123 476 ANVTMQNHVGEKPSQSAERHGHTMCSRYL 504
Cdd:COG0666   210 ADVNAKDNDGKTALDLAAENGNLEIVKLL 238
SNCAIP_SNCA_bd super family cl25051
Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is ...
 507-550 2.63e-10

Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is responsible for binding to alpha-Synuclein.


The actual alignment was detected with superfamily member pfam16700:

Pssm-ID: 435527  Cd Length: 45  Bit Score: 56.28  E-value: 2.63e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2024432123 507 VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQLLEAQRPEGK 550
Cdd:pfam16700   1 VETCMSLASQVVKLTKQLHEQTAARIAIQKHLQLLFDPQDAEGR 44
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
317-504 5.23e-23

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 100.41  E-value: 5.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 317 ILNIVKEGQISLLPHLAADNLDKIHDECDNNLLHVAASKGHAECLQHLTSLmGEDcLNERNIEQLTPAGLAIKNGQLECV 396
Cdd:COG0666    59 LAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEA-GAD-VNARDKDGETPLHLAAYNGNLEIV 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 397 RWMVsetEAIAEL-SCSKDHPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNTAVHIAAQHGYLGCIQTLVEYG 475
Cdd:COG0666   137 KLLL---EAGADVnAQDNDGNTPLHLAAANGNLEIVKLLL----EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209

                         170       180
                  ....*....|....*....|....*....
gi 2024432123 476 ANVTMQNHVGEKPSQSAERHGHTMCSRYL 504
Cdd:COG0666   210 ADVNAKDNDGKTALDLAAENGNLEIVKLL 238
Ank_2 pfam12796
Ankyrin repeats (3 copies);
349-482 3.72e-12

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 63.21  E-value: 3.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 349 LHVAASKGHAECLQHLTSLMGEdcLNERNIEQLTPAGLAIKNGQLECVRWMVSETEAiaelscskdhpslihyagcygqe 428
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGAD--ANLQDKNGRTALHLAAKNGHLEIVKLLLEHADV----------------------- 55

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2024432123 429 killwllqfmqeqgisldEVDQDGNTAVHIAAQHGYLGCIQTLVEYGANVTMQN 482
Cdd:pfam12796  56 ------------------NLKDNGRTALHYAARSGHLEIVKLLLEKGADINVKD 91
SNCAIP_SNCA_bd pfam16700
Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is ...
 507-550 2.63e-10

Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is responsible for binding to alpha-Synuclein.


Pssm-ID: 435527  Cd Length: 45  Bit Score: 56.28  E-value: 2.63e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2024432123 507 VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQLLEAQRPEGK 550
Cdd:pfam16700   1 VETCMSLASQVVKLTKQLHEQTAARIAIQKHLQLLFDPQDAEGR 44
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 316-482 5.06e-05

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 47.17  E-value: 5.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 316 SILNIVKEGQISLLPHLAADNLD-KIHDECDNNLLHVAASKGHAECLqhlTSLMGEDC-LNERNIEQLTPAGLAIKNGQL 393
Cdd:PLN03192  528 NLLTVASTGNAALLEELLKAKLDpDIGDSKGRTPLHIAASKGYEDCV---LVLLKHACnVHIRDANGNTALWNAISAKHH 604

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 394 EcVRWMVSETEAIAElscskdhPsliHYAG---CYGQEKILLWLLQFMQEQGISLDEVDQDGNTAVHIAAQHGYLGCIQT 470
Cdd:PLN03192  605 K-IFRILYHFASISD-------P---HAAGdllCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRL 673

                         170
                  ....*....|..
gi 2024432123 471 LVEYGANVTMQN 482
Cdd:PLN03192  674 LIMNGADVDKAN 685
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 451-480 6.40e-05

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 40.65  E-value: 6.40e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 2024432123  451 DGNTAVHIAAQHGYLGCIQTLVEYGANVTM 480
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
317-504 5.23e-23

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 100.41  E-value: 5.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 317 ILNIVKEGQISLLPHLAADNLDKIHDECDNNLLHVAASKGHAECLQHLTSLmGEDcLNERNIEQLTPAGLAIKNGQLECV 396
Cdd:COG0666    59 LAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEA-GAD-VNARDKDGETPLHLAAYNGNLEIV 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 397 RWMVsetEAIAEL-SCSKDHPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNTAVHIAAQHGYLGCIQTLVEYG 475
Cdd:COG0666   137 KLLL---EAGADVnAQDNDGNTPLHLAAANGNLEIVKLLL----EAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209

                         170       180
                  ....*....|....*....|....*....
gi 2024432123 476 ANVTMQNHVGEKPSQSAERHGHTMCSRYL 504
Cdd:COG0666   210 ADVNAKDNDGKTALDLAAENGNLEIVKLL 238
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
317-505 3.08e-18

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 86.16  E-value: 3.08e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 317 ILNIVKEGQISLLPHLAADNLDKIHDECDNNLLHVAASKGHAECLQHLtsLMGEDCLNERNIEQLTPAGLAIKNGQLECV 396
Cdd:COG0666    26 LAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLL--LAAGADINAKDDGGNTLLHAAARNGDLEIV 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 397 RWMVsetEAIAEL-SCSKDHPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNTAVHIAAQHGYLGCIQTLVEYG 475
Cdd:COG0666   104 KLLL---EAGADVnARDKDGETPLHLAAYNGNLEIVKLLL----EAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAG 176

                         170       180       190
                  ....*....|....*....|....*....|
gi 2024432123 476 ANVTMQNHVGEKPSQSAERHGHTMCSRYLV 505
Cdd:COG0666   177 ADVNARDNDGETPLHLAAENGHLEIVKLLL 206
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
317-497 2.87e-15

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 77.30  E-value: 2.87e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 317 ILNIVKEGQISLLPHLAADNLD-KIHDECDNNLLHVAASKGHAECLQHLTSLmGEDcLNERNIEQLTPAGLAIKNGQLEC 395
Cdd:COG0666    91 LHAAARNGDLEIVKLLLEAGADvNARDKDGETPLHLAAYNGNLEIVKLLLEA-GAD-VNAQDNDGNTPLHLAAANGNLEI 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 396 VRWMVsetEAIAEL-SCSKDHPSLIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDGNTAVHIAAQHGYLGCIQTLVEY 474
Cdd:COG0666   169 VKLLL---EAGADVnARDNDGETPLHLAAENGHLEIVKLLL----EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241

                         170       180
                  ....*....|....*....|...
gi 2024432123 475 GANVTMQNHVGEKPSQSAERHGH 497
Cdd:COG0666   242 GADLNAKDKDGLTALLLAAAAGA 264
Ank_2 pfam12796
Ankyrin repeats (3 copies);
349-482 3.72e-12

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 63.21  E-value: 3.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 349 LHVAASKGHAECLQHLTSLMGEdcLNERNIEQLTPAGLAIKNGQLECVRWMVSETEAiaelscskdhpslihyagcygqe 428
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLENGAD--ANLQDKNGRTALHLAAKNGHLEIVKLLLEHADV----------------------- 55

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2024432123 429 killwllqfmqeqgisldEVDQDGNTAVHIAAQHGYLGCIQTLVEYGANVTMQN 482
Cdd:pfam12796  56 ------------------NLKDNGRTALHYAARSGHLEIVKLLLEKGADINVKD 91
SNCAIP_SNCA_bd pfam16700
Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is ...
 507-550 2.63e-10

Synphilin-1 alpha-Synuclein-binding domain; This coiled-coil domain found in Synphilin-1 is responsible for binding to alpha-Synuclein.


Pssm-ID: 435527  Cd Length: 45  Bit Score: 56.28  E-value: 2.63e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2024432123 507 VETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQLLEAQRPEGK 550
Cdd:pfam16700   1 VETCMSLASQVVKLTKQLHEQTAARIAIQKHLQLLFDPQDAEGR 44
Ank_4 pfam13637
Ankyrin repeats (many copies);
415-472 9.79e-08

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 49.20  E-value: 9.79e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024432123 415 HPSLIHYAGCYGQEKILLWLLQFmqeqGISLDEVDQDGNTAVHIAAQHGYLGCIQTLV 472
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEK----GADINAVDGNGETALHFAASNGNVEVLKLLL 54
Ank_2 pfam12796
Ankyrin repeats (3 copies);
321-401 1.22e-06

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 47.42  E-value: 1.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 321 VKEGQISLLPHLAADNLDK-IHDECDNNLLHVAASKGHAECLQHltsLMGEDCLNERNiEQLTPAGLAIKNGQLECVRWM 399
Cdd:pfam12796   5 AKNGNLELVKLLLENGADAnLQDKNGRTALHLAAKNGHLEIVKL---LLEHADVNLKD-NGRTALHYAARSGHLEIVKLL 80


                  ..
gi 2024432123 400 VS 401
Cdd:pfam12796  81 LE 82
Ank_4 pfam13637
Ankyrin repeats (many copies);
452-505 8.09e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 43.80  E-value: 8.09e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2024432123 452 GNTAVHIAAQHGYLGCIQTLVEYGANVTMQNHVGEKPSQSAERHGHTMCSRYLV 505
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 451-483 3.67e-05

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 41.51  E-value: 3.67e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2024432123 451 DGNTAVHIAA-QHGYLGCIQTLVEYGANVTMQNH 483
Cdd:pfam00023   1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARDK 34
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 316-482 5.06e-05

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 47.17  E-value: 5.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 316 SILNIVKEGQISLLPHLAADNLD-KIHDECDNNLLHVAASKGHAECLqhlTSLMGEDC-LNERNIEQLTPAGLAIKNGQL 393
Cdd:PLN03192  528 NLLTVASTGNAALLEELLKAKLDpDIGDSKGRTPLHIAASKGYEDCV---LVLLKHACnVHIRDANGNTALWNAISAKHH 604

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 394 EcVRWMVSETEAIAElscskdhPsliHYAG---CYGQEKILLWLLQFMQEQGISLDEVDQDGNTAVHIAAQHGYLGCIQT 470
Cdd:PLN03192  605 K-IFRILYHFASISD-------P---HAAGdllCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRL 673

                         170
                  ....*....|..
gi 2024432123 471 LVEYGANVTMQN 482
Cdd:PLN03192  674 LIMNGADVDKAN 685
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 417-505 6.37e-05

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 46.50  E-value: 6.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 417 SLIHYAGCYGQEKILLWLLQFMQEQGISldevDQDGNTAVHIAAQHGYLGCIQTLVEYGANVTMQNHVGEKPSQSAERHG 496
Cdd:PHA02874  126 TFLHYAIKKGDLESIKMLFEYGADVNIE----DDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYG 201


                  ....*....
gi 2024432123 497 HTMCSRYLV 505
Cdd:PHA02874  202 DYACIKLLI 210
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 451-480 6.40e-05

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 40.65  E-value: 6.40e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 2024432123  451 DGNTAVHIAAQHGYLGCIQTLVEYGANVTM 480
Cdd:smart00248   1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
Ank_4 pfam13637
Ankyrin repeats (many copies);
346-400 1.06e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 40.72  E-value: 1.06e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2024432123 346 NNLLHVAASKGHAECLQHLTSLmGEDClNERNIEQLTPAGLAIKNGQLECVRWMV 400
Cdd:pfam13637   2 LTALHAAAASGHLELLRLLLEK-GADI-NAVDGNGETALHFAASNGNVEVLKLLL 54
Ank_2 pfam12796
Ankyrin repeats (3 copies);
457-505 1.16e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 41.64  E-value: 1.16e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2024432123 457 HIAAQHGYLGCIQTLVEYGANVTMQNHVGEKPSQSAERHGHTMCSRYLV 505
Cdd:pfam12796   2 HLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL 50
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 440-496 2.26e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 44.89  E-value: 2.26e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024432123 440 EQGISLDEVDQDGNTAVHIAAQHGYLGCIQTLVEYGANVTMQNHVGEKPSQSAERHG 496
Cdd:PTZ00322  103 TGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENG 159
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 373-495 4.08e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 40.72  E-value: 4.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 373 LNERNIEQLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDHPslIHYAGCYGQEKILLWLLqfmqEQGISLDEVDQDG 452
Cdd:PHA02874  117 VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYP--IHIAIKHNFFDIIKLLL----EKGAYANVKDNNG 190

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2024432123 453 NTAVHIAAQHGYLGCIQTLVEYGANVTMQNHVGEKPSQSAERH 495
Cdd:PHA02874  191 ESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIH 233
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 305-478 4.17e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 40.82  E-value: 4.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 305 EERSEEVKKFKSILNIVKEGQI--SLLPHLAADNLDKIhDECDNNLLHVAAskgHAECLQHLTSLM---GEDcLNERNIE 379
Cdd:PHA02876  232 DNRSNINKNDLSLLKAIRNEDLetSLLLYDAGFSVNSI-DDCKNTPLHHAS---QAPSLSRLVPKLlerGAD-VNAKNIK 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 380 QLTPAGLAIKNG-QLECVRWMVSETEAIAELSCSKDHPslIHYAGCYGQEK-ILLWLLqfmqEQGISLDEVDQDGNTAVH 457
Cdd:PHA02876  307 GETPLYLMAKNGyDTENIRTLIMLGADVNAADRLYITP--LHQASTLDRNKdIVITLL----ELGANVNARDYCDKTPIH 380

                         170       180
                  ....*....|....*....|.
gi 2024432123 458 IAAQHGYLGCIQTLVEYGANV 478
Cdd:PHA02876  381 YAAVRNNVVIINTLLDYGADI 401
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 371-495 5.71e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 40.33  E-value: 5.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024432123 371 DCLNERNIEQLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDHPSLIhyAGCYGQEKILLWLL--------------- 435
Cdd:PHA02874   26 NCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLT--AIKIGAHDIIKLLIdngvdtsilpipcie 103

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024432123 436 ----QFMQEQGISLDEVDQDGNTAVHIAAQHGYLGCIQTLVEYGANVTMQNHVGEKPSQSAERH 495
Cdd:PHA02874  104 kdmiKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKH 167
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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