NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2024441949|ref|XP_040515070|]
View 

GRAM domain-containing protein 4 isoform X9 [Gallus gallus]

Protein Classification

PTZ00121 and PH-GRAM_GRAMDC4 domain-containing protein( domain architecture ID 10280254)

protein containing domains PTZ00121, PRT_C, and PH-GRAM_GRAMDC4

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PH-GRAM_GRAMDC4 cd13221
GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like ...
 479-584 7.83e-56

GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain; GRAMDC4 is a membrane protein. Nothing is known about its function. Paralogs include: GRAMDC1A, GRAMDC1B, GRAMDC1C, GRAMDC2, GRAMDC3, and GRAMDC-like proteins. It contains a single PH-GRAM domain at its N-terminus. The GRAM domain is found in glucosyltransferases, myotubularins and other putative membrane-associated proteins. The GRAM domain is part of a larger motif with a pleckstrin homology (PH) domain fold.


:

Pssm-ID: 270041  Cd Length: 104  Bit Score: 183.70  E-value: 7.83e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 479 LAVCENGWRCCLINRDrKMPTDYIRNGILYVTENYLCFESSKSgSSKRNKVIKLTDITDIQKYKVLSVLPGSGMGIAVST 558
Cdd:cd13221     1 LPVWENGWRCCLINRD-KMPTDYIRNGRLYLTENYLCFESSSS-SSKKNVVIPLTDITRIEKAKPYSFLPGSGMSIEVSV 78

                          90       100
                  ....*....|....*....|....*.
gi 2024441949 559 PSTQKPLVFGAMVHRDEAFETIFNQY 584
Cdd:cd13221    79 SSADKPLFFGAMFRRDEFFDIIALGA 104
tolA super family cl35847
cell envelope integrity inner membrane protein TolA; Provisional
 96-158 1.87e-05

cell envelope integrity inner membrane protein TolA; Provisional


The actual alignment was detected with superfamily member PRK09510:

Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 47.11  E-value: 1.87e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024441949  96 EELRKLREETNAETLRQELEKERQRRLELEQKVNEVLKARAEEVSAAQQPAKPQTQANGADKR 158
Cdd:PRK09510   78 EEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAK 140
PRT_C super family cl07117
Plant phosphoribosyltransferase C-terminal; This domain is found at the C-terminus of ...
 305-385 5.91e-03

Plant phosphoribosyltransferase C-terminal; This domain is found at the C-terminus of phosphoribosyltransferases and phosphoribosyltransferase-like proteins. It contains putative transmembrane regions. It often appears together with calcium-ion dependent C2 domains (pfam00168).


The actual alignment was detected with superfamily member pfam08372:

Pssm-ID: 337028  Cd Length: 156  Bit Score: 37.64  E-value: 5.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 305 VAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYIVLWAAFIASCFLPYRIIGLAMGLYagikfflidfiFKRCPRLRA 384
Cdd:pfam08372  67 VAGRVQTVVGDIATQGERLQALLSWRDPRATALFVLFCLLAAVVLYVVPFKVLALLSGFY-----------YLRHPRFRS 135


                  .
gi 2024441949 385 K 385
Cdd:pfam08372 136 R 136
 
Name Accession Description Interval E-value
PH-GRAM_GRAMDC4 cd13221
GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like ...
 479-584 7.83e-56

GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain; GRAMDC4 is a membrane protein. Nothing is known about its function. Paralogs include: GRAMDC1A, GRAMDC1B, GRAMDC1C, GRAMDC2, GRAMDC3, and GRAMDC-like proteins. It contains a single PH-GRAM domain at its N-terminus. The GRAM domain is found in glucosyltransferases, myotubularins and other putative membrane-associated proteins. The GRAM domain is part of a larger motif with a pleckstrin homology (PH) domain fold.


Pssm-ID: 270041  Cd Length: 104  Bit Score: 183.70  E-value: 7.83e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 479 LAVCENGWRCCLINRDrKMPTDYIRNGILYVTENYLCFESSKSgSSKRNKVIKLTDITDIQKYKVLSVLPGSGMGIAVST 558
Cdd:cd13221     1 LPVWENGWRCCLINRD-KMPTDYIRNGRLYLTENYLCFESSSS-SSKKNVVIPLTDITRIEKAKPYSFLPGSGMSIEVSV 78

                          90       100
                  ....*....|....*....|....*.
gi 2024441949 559 PSTQKPLVFGAMVHRDEAFETIFNQY 584
Cdd:cd13221    79 SSADKPLFFGAMFRRDEFFDIIALGA 104
GRAM pfam02893
GRAM domain; The GRAM domain is found in in glucosyltransferases, myotubularins and other ...
 465-584 5.63e-19

GRAM domain; The GRAM domain is found in in glucosyltransferases, myotubularins and other putative membrane-associated proteins. Note the alignment is lacking the last two beta strands and alpha helix.


Pssm-ID: 397160  Cd Length: 112  Bit Score: 82.80  E-value: 5.63e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 465 NFHEVFNLSENERPLAVCengwrCCLINRDRkmptdYIRNGILYVTENYLCFESSKSGSSKRnKVIKLTDITDIQKYKVL 544
Cdd:pfam02893   2 LFRKKFKLPPEERLIASY-----SCYLNRDG-----GPVQGRLYLTNYRLCFRSLPKGWSTK-VVIPLVDIEEIEKLKGG 70

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2024441949 545 SVLPGSGMGIAVSTPStqkPLVFGAMVHRDEAFETIFNQY 584
Cdd:pfam02893  71 ANLFPNGIQVETGSND---KFSFAGFVTRDEAIEFILALL 107
GRAM smart00568
domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins;
471-542 6.88e-09

domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins;


Pssm-ID: 214725 [Multi-domain]  Cd Length: 60  Bit Score: 52.21  E-value: 6.88e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024441949  471 NLSENERPLAVcengWRCCLINrdrkmptDYIRNGILYVTENYLCFESSKSGSSKrNKVIKLTDITDIQKYK 542
Cdd:smart00568   1 KLPEEEKLIAD----YSCYLSR-------TGPVQGRLYISNYRLCFRSNLPGKLT-KVVIPLADITRIEKST 60
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 96-158 1.87e-05

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 47.11  E-value: 1.87e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024441949  96 EELRKLREETNAETLRQELEKERQRRLELEQKVNEVLKARAEEVSAAQQPAKPQTQANGADKR 158
Cdd:PRK09510   78 EEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAK 140
PRT_C pfam08372
Plant phosphoribosyltransferase C-terminal; This domain is found at the C-terminus of ...
 305-385 5.91e-03

Plant phosphoribosyltransferase C-terminal; This domain is found at the C-terminus of phosphoribosyltransferases and phosphoribosyltransferase-like proteins. It contains putative transmembrane regions. It often appears together with calcium-ion dependent C2 domains (pfam00168).


Pssm-ID: 337028  Cd Length: 156  Bit Score: 37.64  E-value: 5.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 305 VAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYIVLWAAFIASCFLPYRIIGLAMGLYagikfflidfiFKRCPRLRA 384
Cdd:pfam08372  67 VAGRVQTVVGDIATQGERLQALLSWRDPRATALFVLFCLLAAVVLYVVPFKVLALLSGFY-----------YLRHPRFRS 135


                  .
gi 2024441949 385 K 385
Cdd:pfam08372 136 R 136
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 59-147 6.54e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 6.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949  59 TIIMASGVQDFNRTESDRLNEIKGHL-EIALLEKHFLQEELRKLREETNAETLRQELEKERQRRLELEQKVNEVLKARAE 137
Cdd:COG4942   134 AVRRLQYLKYLAPARREQAEELRADLaELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA 213

                          90
                  ....*....|
gi 2024441949 138 EVSAAQQPAK 147
Cdd:COG4942   214 ELAELQQEAE 223
 
Name Accession Description Interval E-value
PH-GRAM_GRAMDC4 cd13221
GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like ...
 479-584 7.83e-56

GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain; GRAMDC4 is a membrane protein. Nothing is known about its function. Paralogs include: GRAMDC1A, GRAMDC1B, GRAMDC1C, GRAMDC2, GRAMDC3, and GRAMDC-like proteins. It contains a single PH-GRAM domain at its N-terminus. The GRAM domain is found in glucosyltransferases, myotubularins and other putative membrane-associated proteins. The GRAM domain is part of a larger motif with a pleckstrin homology (PH) domain fold.


Pssm-ID: 270041  Cd Length: 104  Bit Score: 183.70  E-value: 7.83e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 479 LAVCENGWRCCLINRDrKMPTDYIRNGILYVTENYLCFESSKSgSSKRNKVIKLTDITDIQKYKVLSVLPGSGMGIAVST 558
Cdd:cd13221     1 LPVWENGWRCCLINRD-KMPTDYIRNGRLYLTENYLCFESSSS-SSKKNVVIPLTDITRIEKAKPYSFLPGSGMSIEVSV 78

                          90       100
                  ....*....|....*....|....*.
gi 2024441949 559 PSTQKPLVFGAMVHRDEAFETIFNQY 584
Cdd:cd13221    79 SSADKPLFFGAMFRRDEFFDIIALGA 104
GRAM pfam02893
GRAM domain; The GRAM domain is found in in glucosyltransferases, myotubularins and other ...
 465-584 5.63e-19

GRAM domain; The GRAM domain is found in in glucosyltransferases, myotubularins and other putative membrane-associated proteins. Note the alignment is lacking the last two beta strands and alpha helix.


Pssm-ID: 397160  Cd Length: 112  Bit Score: 82.80  E-value: 5.63e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 465 NFHEVFNLSENERPLAVCengwrCCLINRDRkmptdYIRNGILYVTENYLCFESSKSGSSKRnKVIKLTDITDIQKYKVL 544
Cdd:pfam02893   2 LFRKKFKLPPEERLIASY-----SCYLNRDG-----GPVQGRLYLTNYRLCFRSLPKGWSTK-VVIPLVDIEEIEKLKGG 70

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2024441949 545 SVLPGSGMGIAVSTPStqkPLVFGAMVHRDEAFETIFNQY 584
Cdd:pfam02893  71 ANLFPNGIQVETGSND---KFSFAGFVTRDEAIEFILALL 107
PH-GRAM cd10570
Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins ...
 482-584 9.02e-13

Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain; Myotubularin-related proteins are a subfamily of protein tyrosine phosphatases (PTPs) that dephosphorylate D3-phosphorylated inositol lipids. Mutations in this family cause the human neuromuscular disorders myotubular myopathy and type 4B Charcot-Marie-Tooth syndrome. 6 of the 13 MTMRs (MTMRs 5, 9-13) contain naturally occurring substitutions of residues required for catalysis by PTP family enzymes. Although these proteins are predicted to be enzymatically inactive, they are thought to function as antagonists of endogenous phosphatase activity or interaction modules. Most MTMRs contain a N-terminal PH-GRAM domain, a Rac-induced recruitment domain (RID) domain, a PTP domain (which may be active or inactive), a SET-interaction domain, and a C-terminal coiled-coil region. In addition some members contain DENN domain N-terminal to the PH-GRAM domain and FYVE, PDZ, and PH domains C-terminal to the coiled-coil region. The GRAM domain, found in myotubularins, glucosyltransferases, and other putative membrane-associated proteins, is part of a larger motif with a pleckstrin homology (PH) domain fold.


Pssm-ID: 275393  Cd Length: 94  Bit Score: 64.32  E-value: 9.02e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 482 CENGWRCCLINRDRKMPtdyiRNGILYVTENYLCFESSKSGsSKRNKVIKLTDITDIQKYKVLSVLPgSGMGIAVSTPST 561
Cdd:cd10570     2 EKLGVRFCCALRPRKLP----LEGTLYLSTYRLIFSSKADG-DETKLVIPLVDITDVEKIAGASFLP-SGLIITCKDFRT 75

                          90       100
                  ....*....|....*....|...
gi 2024441949 562 QKPLVFGAMvhrdEAFETIFNQY 584
Cdd:cd10570    76 IKFSFDSED----EAVKVIARVL 94
PH-GRAM_GRAMDC cd13220
GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like ...
 505-583 9.46e-11

GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain; The GRAMDC proteins are membrane proteins. Nothing is known about its function. Members include: GRAMDC1A, GRAMDC1B, GRAMDC1C, GRAMDC2, GRAMDC3, GRAMDC4, and GRAMDC-like proteins. All of the members, except for GRAMDC4 are included in this hierarchy. Each contains a single PH-GRAM domain at their N-terminus. The GRAM domain is found in glucosyltransferases, myotubularins and other putative membrane-associated proteins. The GRAM domain is part of a larger motif with a pleckstrin homology (PH) domain fold.


Pssm-ID: 275406  Cd Length: 94  Bit Score: 58.67  E-value: 9.46e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024441949 505 GILYVTENYLCFESSKSGsSKRNKVIKLTDITDIQKYKVLSVLPGSgmgIAVSTPSTQkpLVFGAMVHRDEAFETIFNQ 583
Cdd:cd13220    21 GRLYISENHLCFYSNIFG-WETKLVIPFKDITSIEKKKTALIFPNA---IEITTKGEK--YFFTSFLSRDSAYKLLTRV 93
GRAM smart00568
domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins;
471-542 6.88e-09

domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins;


Pssm-ID: 214725 [Multi-domain]  Cd Length: 60  Bit Score: 52.21  E-value: 6.88e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024441949  471 NLSENERPLAVcengWRCCLINrdrkmptDYIRNGILYVTENYLCFESSKSGSSKrNKVIKLTDITDIQKYK 542
Cdd:smart00568   1 KLPEEEKLIAD----YSCYLSR-------TGPVQGRLYISNYRLCFRSNLPGKLT-KVVIPLADITRIEKST 60
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 96-158 1.87e-05

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 47.11  E-value: 1.87e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024441949  96 EELRKLREETNAETLRQELEKERQRRLELEQKVNEVLKARAEEVSAAQQPAKPQTQANGADKR 158
Cdd:PRK09510   78 EEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAK 140
PH-GRAM1_TCB1D9_TCB1D9B cd13351
TBC1 domain family members 9 and 9B (TBC1D9 and TBC1D9B) Pleckstrin ...
 484-578 5.47e-04

TBC1 domain family members 9 and 9B (TBC1D9 and TBC1D9B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1; TBC1D9 and TCB1D9B may act as a GTPase-activating proteins for Rab family protein(s). TBC1D9 and TCB1D9B contain two N-terminal PH-GRAM domain and a C-terminal Rab-GTPase-TBC (Tre-2, BUB2p, and Cdc16p) domain. This cd contains the first repeat of the PH-GRAM domain. The GRAM domain is found in glucosyltransferases, myotubularins and other putative membrane-associated proteins. The GRAM domain is part of a larger motif with a pleckstrin homology (PH) domain fold.


Pssm-ID: 275420  Cd Length: 99  Bit Score: 39.68  E-value: 5.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 484 NGWRCCLINRdrKMPtdyiRNGILYVTENYLCFESSKSGSSKRnKVIKLTDITDIQKYKVLsVLPGSgmgIAVSTPStqK 563
Cdd:cd13351     6 NYYSCSYWKG--RVP----RQGWLYLSVNHLCFYSFLLGKEAK-LVIRWTDVTQLEKNNSL-LLPDS---IKVVTRD--K 72

                          90
                  ....*....|....*
gi 2024441949 564 PLVFGAMVHRDEAFE 578
Cdd:cd13351    73 EHYFSMFLNISETFK 87
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 72-160 1.43e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 1.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949  72 TESDRLNE-IKG--HLEIALLEKHflqEELRKLREEtnAETLRQELEK--------ERQRRLELEQKVNEVLKARAEEVS 140
Cdd:PRK00409  513 EDKEKLNElIASleELERELEQKA---EEAEALLKE--AEKLKEELEEkkeklqeeEDKLLEEAEKEAQQAIKEAKKEAD 587

                          90       100
                  ....*....|....*....|
gi 2024441949 141 AAQQPAKPQTQANGADKRSH 160
Cdd:PRK00409  588 EIIKELRQLQKGGYASVKAH 607
rpsP PRK14521
30S ribosomal protein S16; Provisional
 81-155 2.17e-03

30S ribosomal protein S16; Provisional


Pssm-ID: 237744 [Multi-domain]  Cd Length: 186  Bit Score: 39.38  E-value: 2.17e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024441949  81 KGHLEIALLEKHF---LQEELRKLreETNAETLRQELEKERQRRLELEQKVNEVLKARAEEVSAAQQPAKPQTQANGA 155
Cdd:PRK14521   91 KGAFTEAQAEAKFeawKEEKEGKV--NAKKDKLSKAKKAAKKAALEAEKKVNEARAEAVAEKKAAEAAAVAAEEAAAA 166
PRT_C pfam08372
Plant phosphoribosyltransferase C-terminal; This domain is found at the C-terminus of ...
 305-385 5.91e-03

Plant phosphoribosyltransferase C-terminal; This domain is found at the C-terminus of phosphoribosyltransferases and phosphoribosyltransferase-like proteins. It contains putative transmembrane regions. It often appears together with calcium-ion dependent C2 domains (pfam00168).


Pssm-ID: 337028  Cd Length: 156  Bit Score: 37.64  E-value: 5.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949 305 VAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYIVLWAAFIASCFLPYRIIGLAMGLYagikfflidfiFKRCPRLRA 384
Cdd:pfam08372  67 VAGRVQTVVGDIATQGERLQALLSWRDPRATALFVLFCLLAAVVLYVVPFKVLALLSGFY-----------YLRHPRFRS 135


                  .
gi 2024441949 385 K 385
Cdd:pfam08372 136 R 136
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 59-147 6.54e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 6.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024441949  59 TIIMASGVQDFNRTESDRLNEIKGHL-EIALLEKHFLQEELRKLREETNAETLRQELEKERQRRLELEQKVNEVLKARAE 137
Cdd:COG4942   134 AVRRLQYLKYLAPARREQAEELRADLaELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA 213

                          90
                  ....*....|
gi 2024441949 138 EVSAAQQPAK 147
Cdd:COG4942   214 ELAELQQEAE 223
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH