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Conserved domains on  [gi|2024448128|ref|XP_040517747|]
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sushi repeat-containing protein SRPX isoform X5 [Gallus gallus]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 11248451)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4174 pfam13778
Domain of unknown function (DUF4174); This domain of unknown function is found in a putative ...
 385-504 3.15e-45

Domain of unknown function (DUF4174); This domain of unknown function is found in a putative tumour suppressor gene and in a ligand for the the urokinase-type plasminogen activator receptor, which plays a role in cellular migration and adhesion.


:

Pssm-ID: 463980  Cd Length: 120  Bit Score: 154.71  E-value: 3.15e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 385 LLDQFYEKRRLLIISTPTAANFFYRMQLGMLQPAQCGLDLRHVTVVELVGIFPAQIGRIGVKLLPPSLALQLRLLLRIPH 464
Cdd:pfam13778   1 PLDQFRWKRRLLIISAPSADDPYYRQQLDALQAAECGLAERDLTVIELVGSGPNETGKIEHEQLSPDLIEELRKELGIPR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2024448128 465 YNFNIVVMDKHGMDKERYPFPATPAELFALIDNFPLRKEE 504
Cdd:pfam13778  81 NYFSMVLIGKDGGVKERYPAPVSLEALFDLIDAMPMRQQE 120
HYR pfam02494
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ...
 228-310 1.50e-33

HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.


:

Pssm-ID: 460572 [Multi-domain]  Cd Length: 81  Bit Score: 121.73  E-value: 1.50e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 228 VDTEPPRIQCPSVKEKIAEPNKLTARVFWDTPEGRDTADGilTDVILKGLPPGSHFPEGDHKIQYTVYDRAENKGTCKFL 307
Cdd:pfam02494   1 VDTTPPTVKCPNNIVRTVELGTSTVRVFFTEPTAFDNSGQ--AILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFT 78


                  ...
gi 2024448128 308 VKV 310
Cdd:pfam02494  79 VTV 81
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 315-370 1.26e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 65.56  E-value: 1.26e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128 315 CVKLNVPDNGYIKCSGDGNNYGATCEFSCIGGYELQGSPARVCQYNLGWSGVEPTC 370
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 173-228 1.69e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.10  E-value: 1.69e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024448128 173 CPTLSMPTNGGFKCLDGAY-FGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASCV 228
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYsYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 112-166 1.52e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.51  E-value: 1.52e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024448128  112 PIKVKHGYANCRTPQGEYyknvlGTRCDIRCQKGYELHGPQQLICQSSKRWSGKV 166
Cdd:smart00032   4 PPDIENGTVTSSSGTYSY-----GDTVTYSCDPGYTLIGSSTITCLENGTWSPPP 53
 
Name Accession Description Interval E-value
DUF4174 pfam13778
Domain of unknown function (DUF4174); This domain of unknown function is found in a putative ...
 385-504 3.15e-45

Domain of unknown function (DUF4174); This domain of unknown function is found in a putative tumour suppressor gene and in a ligand for the the urokinase-type plasminogen activator receptor, which plays a role in cellular migration and adhesion.


Pssm-ID: 463980  Cd Length: 120  Bit Score: 154.71  E-value: 3.15e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 385 LLDQFYEKRRLLIISTPTAANFFYRMQLGMLQPAQCGLDLRHVTVVELVGIFPAQIGRIGVKLLPPSLALQLRLLLRIPH 464
Cdd:pfam13778   1 PLDQFRWKRRLLIISAPSADDPYYRQQLDALQAAECGLAERDLTVIELVGSGPNETGKIEHEQLSPDLIEELRKELGIPR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2024448128 465 YNFNIVVMDKHGMDKERYPFPATPAELFALIDNFPLRKEE 504
Cdd:pfam13778  81 NYFSMVLIGKDGGVKERYPAPVSLEALFDLIDAMPMRQQE 120
HYR pfam02494
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ...
 228-310 1.50e-33

HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.


Pssm-ID: 460572 [Multi-domain]  Cd Length: 81  Bit Score: 121.73  E-value: 1.50e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 228 VDTEPPRIQCPSVKEKIAEPNKLTARVFWDTPEGRDTADGilTDVILKGLPPGSHFPEGDHKIQYTVYDRAENKGTCKFL 307
Cdd:pfam02494   1 VDTTPPTVKCPNNIVRTVELGTSTVRVFFTEPTAFDNSGQ--AILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFT 78


                  ...
gi 2024448128 308 VKV 310
Cdd:pfam02494  79 VTV 81
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 315-370 1.26e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 65.56  E-value: 1.26e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128 315 CVKLNVPDNGYIKCSGDGNNYGATCEFSCIGGYELQGSPARVCQYNLGWSGVEPTC 370
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
315-370 5.44e-13

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 63.67  E-value: 5.44e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128 315 CVKLNVPDNGYIKCSGDGNNYGATCEFSCIGGYELQGSPARVCQYNLGWSGVEPTC 370
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 173-228 1.69e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.10  E-value: 1.69e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024448128 173 CPTLSMPTNGGFKCLDGAY-FGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASCV 228
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYsYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 315-370 5.00e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 61.00  E-value: 5.00e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128  315 CVKLNVPDNGYIKCSGDGNNYGATCEFSCIGGYELQGSPARVCQYNLGWSGVEPTC 370
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 173-227 6.58e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 60.62  E-value: 6.58e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128  173 CPTLSMPTNGGFKCLDGAY-FGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASC 227
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
173-227 1.10e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 51.35  E-value: 1.10e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128 173 CPTLSMPTNGGFKCLDGAY-FGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASC 227
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYnYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 112-166 1.52e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.51  E-value: 1.52e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024448128  112 PIKVKHGYANCRTPQGEYyknvlGTRCDIRCQKGYELHGPQQLICQSSKRWSGKV 166
Cdd:smart00032   4 PPDIENGTVTSSSGTYSY-----GDTVTYSCDPGYTLIGSSTITCLENGTWSPPP 53
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 112-169 3.05e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 41.68  E-value: 3.05e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024448128 112 PIKVKHGYANCRTPQGEYyknvlGTRCDIRCQKGYELHGPQQLICQSSKRWSGKVL-CK 169
Cdd:cd00033     4 PPVPENGTVTGSKGSYSY-----GSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPtCE 57
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 106-228 1.08e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 43.87  E-value: 1.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 106 ETPWCSPIKvkhgyanCRTPQG----------EYYKNvlGTRCDIRCQKGYELHGPQQLICqSSKRWSGKVLCKQKRCPT 175
Cdd:PHA02927  139 EAPICESVK-------CQSPPSisngrhngyeDFYTD--GSVVTYSCNSGYSLIGNSGVLC-SGGEWSDPPTCQIVKCPH 208

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024448128 176 LSMpTNG----GFKclDGAYFGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASCV 228
Cdd:PHA02927  209 PTI-SNGylssGFK--RSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCV 262
PHA02639 PHA02639
EEV host range protein; Provisional
 146-232 4.67e-04

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 42.34  E-value: 4.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 146 YELHGPQQLICQSSKRWS-GKVLCKQKRC--PTLSMPTNGGFKCLDGAYFGSRCEYYCSPGYQLKGDRIVTCMDNKAWSG 222
Cdd:PHA02639  121 YSLVGNEKITCIQDKSWKpDPPICKMINCrfPALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFP 200

                          90
                  ....*....|
gi 2024448128 223 RPASCVDTEP 232
Cdd:PHA02639  201 SIPTCVRNKP 210
 
Name Accession Description Interval E-value
DUF4174 pfam13778
Domain of unknown function (DUF4174); This domain of unknown function is found in a putative ...
 385-504 3.15e-45

Domain of unknown function (DUF4174); This domain of unknown function is found in a putative tumour suppressor gene and in a ligand for the the urokinase-type plasminogen activator receptor, which plays a role in cellular migration and adhesion.


Pssm-ID: 463980  Cd Length: 120  Bit Score: 154.71  E-value: 3.15e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 385 LLDQFYEKRRLLIISTPTAANFFYRMQLGMLQPAQCGLDLRHVTVVELVGIFPAQIGRIGVKLLPPSLALQLRLLLRIPH 464
Cdd:pfam13778   1 PLDQFRWKRRLLIISAPSADDPYYRQQLDALQAAECGLAERDLTVIELVGSGPNETGKIEHEQLSPDLIEELRKELGIPR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2024448128 465 YNFNIVVMDKHGMDKERYPFPATPAELFALIDNFPLRKEE 504
Cdd:pfam13778  81 NYFSMVLIGKDGGVKERYPAPVSLEALFDLIDAMPMRQQE 120
HYR pfam02494
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ...
 228-310 1.50e-33

HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.


Pssm-ID: 460572 [Multi-domain]  Cd Length: 81  Bit Score: 121.73  E-value: 1.50e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 228 VDTEPPRIQCPSVKEKIAEPNKLTARVFWDTPEGRDTADGilTDVILKGLPPGSHFPEGDHKIQYTVYDRAENKGTCKFL 307
Cdd:pfam02494   1 VDTTPPTVKCPNNIVRTVELGTSTVRVFFTEPTAFDNSGQ--AILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFT 78


                  ...
gi 2024448128 308 VKV 310
Cdd:pfam02494  79 VTV 81
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 315-370 1.26e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 65.56  E-value: 1.26e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128 315 CVKLNVPDNGYIKCSGDGNNYGATCEFSCIGGYELQGSPARVCQYNLGWSGVEPTC 370
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
315-370 5.44e-13

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 63.67  E-value: 5.44e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128 315 CVKLNVPDNGYIKCSGDGNNYGATCEFSCIGGYELQGSPARVCQYNLGWSGVEPTC 370
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 173-228 1.69e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.10  E-value: 1.69e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024448128 173 CPTLSMPTNGGFKCLDGAY-FGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASCV 228
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYsYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 315-370 5.00e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 61.00  E-value: 5.00e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128  315 CVKLNVPDNGYIKCSGDGNNYGATCEFSCIGGYELQGSPARVCQYNLGWSGVEPTC 370
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 173-227 6.58e-12

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 60.62  E-value: 6.58e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128  173 CPTLSMPTNGGFKCLDGAY-FGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASC 227
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
173-227 1.10e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 51.35  E-value: 1.10e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024448128 173 CPTLSMPTNGGFKCLDGAY-FGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASC 227
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYnYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 112-166 1.52e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.51  E-value: 1.52e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024448128  112 PIKVKHGYANCRTPQGEYyknvlGTRCDIRCQKGYELHGPQQLICQSSKRWSGKV 166
Cdd:smart00032   4 PPDIENGTVTSSSGTYSY-----GDTVTYSCDPGYTLIGSSTITCLENGTWSPPP 53
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 112-169 3.05e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 41.68  E-value: 3.05e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024448128 112 PIKVKHGYANCRTPQGEYyknvlGTRCDIRCQKGYELHGPQQLICQSSKRWSGKVL-CK 169
Cdd:cd00033     4 PPVPENGTVTGSKGSYSY-----GSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPtCE 57
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 106-228 1.08e-04

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 43.87  E-value: 1.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 106 ETPWCSPIKvkhgyanCRTPQG----------EYYKNvlGTRCDIRCQKGYELHGPQQLICqSSKRWSGKVLCKQKRCPT 175
Cdd:PHA02927  139 EAPICESVK-------CQSPPSisngrhngyeDFYTD--GSVVTYSCNSGYSLIGNSGVLC-SGGEWSDPPTCQIVKCPH 208

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024448128 176 LSMpTNG----GFKclDGAYFGSRCEYYCSPGYQLKGDRIVTCMDNKAWSGRPASCV 228
Cdd:PHA02927  209 PTI-SNGylssGFK--RSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCV 262
PHA02639 PHA02639
EEV host range protein; Provisional
 146-232 4.67e-04

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 42.34  E-value: 4.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 146 YELHGPQQLICQSSKRWS-GKVLCKQKRC--PTLSMPTNGGFKCLDGAYFGSRCEYYCSPGYQLKGDRIVTCMDNKAWSG 222
Cdd:PHA02639  121 YSLVGNEKITCIQDKSWKpDPPICKMINCrfPALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFP 200

                          90
                  ....*....|
gi 2024448128 223 RPASCVDTEP 232
Cdd:PHA02639  201 SIPTCVRNKP 210
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 110-230 3.37e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 39.68  E-value: 3.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024448128 110 CSPIKVKHGyaNCRtPQGEYYKnvLGTRCDIRCQKGYELHGPQQLICqSSKRWSGKVLCKQK-RCPTLSmptNGgfkCLD 188
Cdd:PHA02954  130 CQPLQLEHG--SCQ-PVKEKYS--FGEHITINCDVGYEVIGASYISC-TANSWNVIPSCQQKcDIPSLS---NG---LIS 197

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2024448128 189 GAYF--GSRCEYYCSPGYQLKGDRIVTCMDNKaWSGRPASCVDT 230
Cdd:PHA02954  198 GSTFsiGGVIHLSCKSGFTLTGSPSSTCIDGK-WNPVLPICVRS 240
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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