|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
54-406 |
9.70e-141 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 405.30 E-value: 9.70e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 54 TPATTLKEKPDPTGLVFGTVFTDNMLTIEWSsASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFR 133
Cdd:PRK13357 8 NPTSDEKRAIDWANLGFGYVFTDHMVVIDYK-DGKWHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLFR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 134 PSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWV-PYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVG 212
Cdd:PRK13357 87 PDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVpPYGEGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPVG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 213 AYFSSEcFNPISLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYGEDHQ-ITEVGTMNLFLywINE 291
Cdd:PRK13357 167 AYFKGG-VKPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFFF--ITK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 292 DGEnelATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAALEENRVKEMFGAGTACIVCPISKILYKGKHL 371
Cdd:PRK13357 244 DGT---VTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGIKYKDKEF 319
|
330 340 350
....*....|....*....|....*....|....*..
gi 2024449537 372 HIPTMENGPqLTTQILNKLTDIQYGR-EDS-DWTVLV 406
Cdd:PRK13357 320 VIGDGEVGP-VTQKLYDELTGIQFGDvEDPhGWIVKV 355
|
|
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
101-396 |
1.60e-134 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 386.55 E-value: 1.60e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 101 SLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAAS 180
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 181 LYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFsSECFNPISLWADPkYVRAWKGGTGDCKLGGNYGSSICAQQEALE 260
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYF-KGGEKGVSALVSS-FRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 261 LGCQQVLWLYGEDHQITEVGTMNLFLYWinedgENELATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTaa 340
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK-----DGELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELY-- 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024449537 341 leenRVKEMFGAGTACIVCPISKILYKGKhlhIPTMENGPQLTTQILNKLTDIQYG 396
Cdd:cd01557 231 ----EADEVFATGTAAVVTPVGEIDYRGK---EPGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
89-406 |
3.85e-104 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 310.54 E-value: 3.85e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 89 WEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEV 168
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 169 EKEWVP-YSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFSSEcFNPISLWADPKYVRAWKGGTGDCKLGGN 247
Cdd:TIGR01123 81 NKDWVPpYGSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKGG-LAPVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 248 YGSSICAQQEALELGCQQVLWL-YGEDHQITEVGTMNLFLywINEDGenELATPPLDGIILPGVTRQSILDLARNWGeFK 326
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLdPVEHTYIEEVGAMNFFF--ITGDG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 327 VSERYITMSDLTAALEenRVKEMFGAGTACIVCPISKILYKGKHLHIPTMENGPqLTTQILNKLTDIQYGR-EDS-DWTV 404
Cdd:TIGR01123 235 VEERRIDIDELKAFVE--AGEIVFACGTAAVITPVGEIQHGGKEVVFASGQPGE-VTKALYDELTDIQYGDfEDPyGWIV 311
|
..
gi 2024449537 405 LV 406
Cdd:TIGR01123 312 EV 313
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
94-399 |
1.63e-76 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 238.94 E-value: 1.63e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 94 IRPLQNLSLHPACSSLHYATELFEGMKAYRGvdgkiRLFRPSLNMDRMARSARRMTLPC-FDQNELLECIRKLVEVEKew 172
Cdd:COG0115 9 LVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPIpYTEEELLEAIRELVAANG-- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 173 vpystAASLYIRPTLIGTEPSLGVKKPT-KALLYVILSPVGAYFSSECFNPISLWADPkYVRAWKGGTGDCKlGGNYGSS 251
Cdd:COG0115 82 -----LEDGYIRPQVTRGVGGRGVFAEEyEPTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TGNYLNN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 252 ICAQQEALELGCQQVLWLYGEDHqITEVGTMNLFLYwinEDGEneLATPPLDGIILPGVTRQSILDLARNWGeFKVSERY 331
Cdd:COG0115 155 VLAKQEAKEAGADEALLLDTDGY-VAEGSGSNVFIV---KDGV--LVTPPLSGGILPGITRDSVIELARELG-IPVEERP 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024449537 332 ITMSDLTAAleenrvKEMFGAGTACIVCPISKIlykgKHLHIPTMENGPqLTTQILNKLTDIQYGRED 399
Cdd:COG0115 228 ISLEELYTA------DEVFLTGTAAEVTPVTEI----DGRPIGDGKPGP-VTRRLRELYTDIVRGEAE 284
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
115-364 |
3.19e-34 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 126.70 E-value: 3.19e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 115 LFEGMKAYRGvdgkiRLFRPSLNMDRMARSARRMTLP-CFDQNELLECIRKLVEVEKEWVPYstaaslyIRPTLIGTEPS 193
Cdd:pfam01063 2 VFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVGR-------LRLTVSRGPGG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 194 LGVKKPT-KALLYVILSPVGAYFSSECFNPISLWADPKYVRAwkggtgDCKlGGNYGSSICAQQEALELGCQQVLwLYGE 272
Cdd:pfam01063 70 FGLPTSDpTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLDE 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 273 DHQITEVGTMNLFLywineDGENELATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAleenrvKEMFGA 352
Cdd:pfam01063 142 DGNVTEGSTSNVFL-----VKGGTLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFLT 209
|
250
....*....|..
gi 2024449537 353 GTACIVCPISKI 364
Cdd:pfam01063 210 NSLRGVTPVSSI 221
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
54-406 |
9.70e-141 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 405.30 E-value: 9.70e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 54 TPATTLKEKPDPTGLVFGTVFTDNMLTIEWSsASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFR 133
Cdd:PRK13357 8 NPTSDEKRAIDWANLGFGYVFTDHMVVIDYK-DGKWHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLFR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 134 PSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWV-PYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVG 212
Cdd:PRK13357 87 PDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVpPYGEGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPVG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 213 AYFSSEcFNPISLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYGEDHQ-ITEVGTMNLFLywINE 291
Cdd:PRK13357 167 AYFKGG-VKPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFFF--ITK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 292 DGEnelATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAALEENRVKEMFGAGTACIVCPISKILYKGKHL 371
Cdd:PRK13357 244 DGT---VTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGIKYKDKEF 319
|
330 340 350
....*....|....*....|....*....|....*..
gi 2024449537 372 HIPTMENGPqLTTQILNKLTDIQYGR-EDS-DWTVLV 406
Cdd:PRK13357 320 VIGDGEVGP-VTQKLYDELTGIQFGDvEDPhGWIVKV 355
|
|
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
101-396 |
1.60e-134 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 386.55 E-value: 1.60e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 101 SLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAAS 180
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 181 LYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFsSECFNPISLWADPkYVRAWKGGTGDCKLGGNYGSSICAQQEALE 260
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYF-KGGEKGVSALVSS-FRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 261 LGCQQVLWLYGEDHQITEVGTMNLFLYWinedgENELATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTaa 340
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK-----DGELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELY-- 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024449537 341 leenRVKEMFGAGTACIVCPISKILYKGKhlhIPTMENGPQLTTQILNKLTDIQYG 396
Cdd:cd01557 231 ----EADEVFATGTAAVVTPVGEIDYRGK---EPGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
89-406 |
3.85e-104 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 310.54 E-value: 3.85e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 89 WEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEV 168
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 169 EKEWVP-YSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFSSEcFNPISLWADPKYVRAWKGGTGDCKLGGN 247
Cdd:TIGR01123 81 NKDWVPpYGSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKGG-LAPVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 248 YGSSICAQQEALELGCQQVLWL-YGEDHQITEVGTMNLFLywINEDGenELATPPLDGIILPGVTRQSILDLARNWGeFK 326
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLdPVEHTYIEEVGAMNFFF--ITGDG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 327 VSERYITMSDLTAALEenRVKEMFGAGTACIVCPISKILYKGKHLHIPTMENGPqLTTQILNKLTDIQYGR-EDS-DWTV 404
Cdd:TIGR01123 235 VEERRIDIDELKAFVE--AGEIVFACGTAAVITPVGEIQHGGKEVVFASGQPGE-VTKALYDELTDIQYGDfEDPyGWIV 311
|
..
gi 2024449537 405 LV 406
Cdd:TIGR01123 312 EV 313
|
|
| PLPDE_IV |
cd00449 |
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, ... |
107-390 |
1.60e-82 |
|
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate lyases (ADCL). BCAT catalyzes the reversible transamination reaction between the L-branched-chain amino and alpha-keto acids. DAAT catalyzes the synthesis of D-glutamic acid and D-alanine, and ADCL converts 4-amino-4-deoxychorismate to p-aminobenzoate and pyruvate. Except for a few enzymes, i. e., Escherichia coli and Salmonella BCATs, which are homohexamers arranged as a double trimer, the class IV PLPDEs are homodimers. Homodimer formation is required for catalytic activity.
Pssm-ID: 238254 [Multi-domain] Cd Length: 256 Bit Score: 253.29 E-value: 1.60e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 107 SSLHYATELFEGMKAYRGvdgkiRLFRPSLNMDRMARSARRMTLP-CFDQNELLECIRKLVEVEKEwvpystaASLYIRP 185
Cdd:cd00449 2 RGLHYGDGVFEGLRAGKG-----RLFRLDEHLDRLNRSAKRLGLPiPYDREELREALKELVAANNG-------ASLYIRP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 186 TLIGTEPSLGV--KKPTKALLYVILSPVGAYFSsECFNPISLWADPKYVRAWKGGTGDCKLGGNYGSsICAQQEALELGC 263
Cdd:cd00449 70 LLTRGVGGLGVapPPSPEPTFVVFASPVGAYAK-GGEKGVRLITSPDRRRAAPGGTGDAKTGGNLNS-VLAKQEAAEAGA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 264 QQVLWLYGEDHqITEVGTMNLFLYWinedgENELATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAlee 343
Cdd:cd00449 148 DEALLLDDNGY-VTEGSASNVFIVK-----DGELVTPPLDGGILPGITRDSVIELAKELG-IKVEERPISLDELYAA--- 217
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2024449537 344 nrvKEMFGAGTACIVCPISKILYKGKHLHIPtmenGPqLTTQILNKL 390
Cdd:cd00449 218 ---DEVFLTGTAAEVTPVTEIDGRGIGDGKP----GP-VTRKLRELL 256
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
94-399 |
1.63e-76 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 238.94 E-value: 1.63e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 94 IRPLQNLSLHPACSSLHYATELFEGMKAYRGvdgkiRLFRPSLNMDRMARSARRMTLPC-FDQNELLECIRKLVEVEKew 172
Cdd:COG0115 9 LVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPIpYTEEELLEAIRELVAANG-- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 173 vpystAASLYIRPTLIGTEPSLGVKKPT-KALLYVILSPVGAYFSSECFNPISLWADPkYVRAWKGGTGDCKlGGNYGSS 251
Cdd:COG0115 82 -----LEDGYIRPQVTRGVGGRGVFAEEyEPTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TGNYLNN 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 252 ICAQQEALELGCQQVLWLYGEDHqITEVGTMNLFLYwinEDGEneLATPPLDGIILPGVTRQSILDLARNWGeFKVSERY 331
Cdd:COG0115 155 VLAKQEAKEAGADEALLLDTDGY-VAEGSGSNVFIV---KDGV--LVTPPLSGGILPGITRDSVIELARELG-IPVEERP 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024449537 332 ITMSDLTAAleenrvKEMFGAGTACIVCPISKIlykgKHLHIPTMENGPqLTTQILNKLTDIQYGRED 399
Cdd:COG0115 228 ISLEELYTA------DEVFLTGTAAEVTPVTEI----DGRPIGDGKPGP-VTRRLRELYTDIVRGEAE 284
|
|
| PLN02782 |
PLN02782 |
Branched-chain amino acid aminotransferase |
70-407 |
1.08e-63 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 215418 Cd Length: 403 Bit Score: 209.70 E-value: 1.08e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 70 FGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARRMT 149
Cdd:PLN02782 77 FGLVPTDYMYIMKCNRDGEFSKGELQRFGNIELSPSAGVLNYGQGLFEGLKAYRKEDGNILLFRPEENAIRMRNGAERMC 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 150 LPCFDQNELLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFsSECFNPISLWADP 229
Cdd:PLN02782 157 MPAPTVEQFVEAVKETVLANKRWVPPPGKGSLYIRPLLMGSGAVLGLAPAPEYTFLIYVSPVGNYF-KEGVAPINLIVEN 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 230 KYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWL------YGEdhqitEVGTMNLFLYwinedGENELATPPLD 303
Cdd:PLN02782 236 EFHRATPGGTGGVKTIGNYAAVLKAQSIAKAKGYSDVLYLdcvhkkYLE-----EVSSCNIFIV-----KDNVISTPAIK 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 304 GIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAleenrvKEMFGAGTACIVCPISKILYKGKHLHIPTMENGpQLT 383
Cdd:PLN02782 306 GTILPGITRKSIIDVARSQG-FQVEERNVTVDELLEA------DEVFCTGTAVVVSPVGSITYKGKRVSYGEGGFG-TVS 377
|
330 340
....*....|....*....|....*.
gi 2024449537 384 TQILNKLTDIQYGR-EDS-DWTVLVS 407
Cdd:PLN02782 378 QQLYTVLTSLQMGLiEDNmNWTVELS 403
|
|
| PLN03117 |
PLN03117 |
Branched-chain-amino-acid aminotransferase; Provisional |
68-406 |
6.39e-59 |
|
Branched-chain-amino-acid aminotransferase; Provisional
Pssm-ID: 178664 Cd Length: 355 Bit Score: 195.92 E-value: 6.39e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 68 LVFGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMARSARR 147
Cdd:PLN03117 25 LGFALVPTDYMYVAKCKQGESFSEGKIVPYGDISISPCAGILNYGQGLFEGLKAYRTEDGRITLFRPDQNALRMQTGADR 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 148 --MTLPCFDQneLLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFSSEcfNPISL 225
Cdd:PLN03117 105 lcMTPPSLEQ--FVEAVKQTVLANKKWVPPPGKGTLYIRPLLIGSGAVLGVAPAPEYTFLIYASPVGNYHKAS--SGLNL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 226 WADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWL-YGEDHQITEVGTMNLFLYwinedGENELATPPLDG 304
Cdd:PLN03117 181 KVDHKHRRAHSGGTGGVKSCTNYSPVVKSLIEAKSSGFSDVLFLdAATGKNIEELSACNIFIL-----KGNIVSTPPTSG 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 305 IILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAleenrvKEMFGAGTACIVCPISKILYKGKHLHIPTMENGpqLTT 384
Cdd:PLN03117 256 TILPGVTRKSISELARDIG-YQVEERDVSVDELLEA------EEVFCTGTAVVVKAVETVTFHDKKVKYRTGEEA--LST 326
|
330 340
....*....|....*....|....
gi 2024449537 385 QILNKLTDIQYGR-EDSD-WTVLV 406
Cdd:PLN03117 327 KLHLILTNIQMGVvEDKKgWMVEI 350
|
|
| PLN02883 |
PLN02883 |
Branched-chain amino acid aminotransferase |
64-407 |
3.11e-49 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 178471 Cd Length: 384 Bit Score: 171.05 E-value: 3.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 64 DPTGLVFGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMAR 143
Cdd:PLN02883 53 DWDKLGFSLVRTDFMFATKSCRDGNFEQGYLSRYGNIELNPAAGILNYGQGLIEGMKAYRGEDGRILLFRPELNAMRMKI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 144 SARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFsSECFNPI 223
Cdd:PLN02883 133 GAERMCMHSPSVHQFIEGVKQTVLANRRWVPPPGKGSLYLRPLLFGSGASLGVAAAPEYTFLVFGSPVQNYF-KEGTAAL 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 224 SLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYGED-HQITEVGTMNLFLYwinedGENELATPPL 302
Cdd:PLN02883 212 NLYVEEVIPRAYLGGTGGVKAISNYGPVLEVMRRAKSRGFSDVLYLDADTgKNIEEVSAANIFLV-----KGNIIVTPAT 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 303 DGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAleenrvKEMFGAGTACIVCPISKILYKGKHLHIPTMENgpQL 382
Cdd:PLN02883 287 SGTILGGITRKSIIEIALDLG-YKVEERRVPVEELKEA------EEVFCTGTAAGVASVGSITFKNTRTEYKVGDG--IV 357
|
330 340
....*....|....*....|....*..
gi 2024449537 383 TTQILNKLTDIQYG--REDSDWTVLVS 407
Cdd:PLN02883 358 TQQLRSILLGIQTGsiQDTKDWVLQIA 384
|
|
| PLN02259 |
PLN02259 |
branched-chain-amino-acid aminotransferase 2 |
64-396 |
2.53e-47 |
|
branched-chain-amino-acid aminotransferase 2
Pssm-ID: 177901 Cd Length: 388 Bit Score: 166.44 E-value: 2.53e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 64 DPTGLVFGTVFTDNMLTIEWSSASGWEKPCIRPLQNLSLHPACSSLHYATELFEGMKAYRGVDGKIRLFRPSLNMDRMAR 143
Cdd:PLN02259 57 DWDNLGFGLNPADYMYVMKCSKDGEFTQGELSPYGNIQLSPSAGVLNYGQAIYEGTKAYRKENGKLLLFRPDHNAIRMKL 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 144 SARRMTLPCFDQNELLECIRKLVEVEKEWVPYSTAASLYIRPTLIGTEPSLGVKKPTKALLYVILSPVGAYFsSECFNPI 223
Cdd:PLN02259 137 GAERMLMPSPSVDQFVNAVKQTALANKRWVPPAGKGTLYIRPLLMGSGPILGLGPAPEYTFIVYASPVGNYF-KEGMAAL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 224 SLWADPKYVRAWKGGTGDCKLGGNYGSSICAQQEALELGCQQVLWLYG-EDHQITEVGTMNLFLYwinedGENELATPPL 302
Cdd:PLN02259 216 NLYVEEEYVRAAPGGAGGVKSITNYAPVLKALSRAKSRGFSDVLYLDSvKKKYLEEASSCNVFVV-----KGRTISTPAT 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 303 DGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAleenrvKEMFGAGTACIVCPISKILYKGKHLHIPTMENgpQL 382
Cdd:PLN02259 291 NGTILEGITRKSVMEIASDQG-YQVVEKAVHVDEVMDA------DEVFCTGTAVVVAPVGTITYQEKRVEYKTGDE--SV 361
|
330
....*....|....
gi 2024449537 383 TTQILNKLTDIQYG 396
Cdd:PLN02259 362 CQKLRSVLVGIQTG 375
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
115-364 |
3.19e-34 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 126.70 E-value: 3.19e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 115 LFEGMKAYRGvdgkiRLFRPSLNMDRMARSARRMTLP-CFDQNELLECIRKLVEVEKEWVPYstaaslyIRPTLIGTEPS 193
Cdd:pfam01063 2 VFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVGR-------LRLTVSRGPGG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 194 LGVKKPT-KALLYVILSPVGAYFSSECFNPISLWADPKYVRAwkggtgDCKlGGNYGSSICAQQEALELGCQQVLwLYGE 272
Cdd:pfam01063 70 FGLPTSDpTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLDE 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 273 DHQITEVGTMNLFLywineDGENELATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAleenrvKEMFGA 352
Cdd:pfam01063 142 DGNVTEGSTSNVFL-----VKGGTLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFLT 209
|
250
....*....|..
gi 2024449537 353 GTACIVCPISKI 364
Cdd:pfam01063 210 NSLRGVTPVSSI 221
|
|
| PRK06606 |
PRK06606 |
branched-chain amino acid transaminase; |
108-402 |
7.79e-34 |
|
branched-chain amino acid transaminase;
Pssm-ID: 235841 Cd Length: 306 Bit Score: 127.96 E-value: 7.79e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 108 SLHYATELFEGMKAYRGVDGKIrLFRPSLNMDRMARSAR--RMTLPcFDQNELLECIRKLVEVEKewvpystAASLYIRP 185
Cdd:PRK06606 29 ALHYGTGVFEGIRAYDTPKGPA-IFRLREHTKRLFNSAKilRMEIP-YSVDELMEAQREVVRKNN-------LKSAYIRP 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 186 -TLIGTEpSLGV---KKPTKALLYVIlsPVGAYFSSECFNP-----ISLW--ADPKY--VRAwkggtgdcKLGGNYGSSI 252
Cdd:PRK06606 100 lVFVGDE-GLGVrphGLPTDVAIAAW--PWGAYLGEEALEKgirvkVSSWtrHAPNSipTRA--------KASGNYLNSI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 253 CAQQEALELGCQQVLWLygeDHQ--ITEVGTMNLFlywINEDGEneLATPPLDGIILPGVTRQSILDLARNWGeFKVSER 330
Cdd:PRK06606 169 LAKTEARRNGYDEALLL---DVEgyVSEGSGENIF---IVRDGV--LYTPPLTSSILEGITRDTVITLAKDLG-IEVIER 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024449537 331 YITMSDLTAAleenrvKEMFGAGTACIVCPISKIlykgKHLHIPTMENGPqLTTQILNKLTDIQYGRED--SDW 402
Cdd:PRK06606 240 RITRDELYIA------DEVFFTGTAAEVTPIREV----DGRQIGNGKRGP-ITEKLQSAYFDIVRGRTEkyAHW 302
|
|
| ilvE_I |
TIGR01122 |
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are ... |
108-364 |
1.54e-25 |
|
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family more strongly similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130192 Cd Length: 298 Bit Score: 105.13 E-value: 1.54e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 108 SLHYATELFEGMKAYRGVDGkIRLFRPSLNMDRMARSARRMTLPC-FDQNELLECIRKLVEVEKewvpystAASLYIRPT 186
Cdd:TIGR01122 20 ALHYGTGVFEGIRAYDTDKG-PAIFRLKEHIQRLYDSAKIYRMEIpYSKEELMEATRETLRKNN-------LRSAYIRPL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 187 LIGTEPSLGV--KKPTKALLYVILSPVGAYFSSECFNP-----ISLW--ADPKYVrawkggTGDCKLGGNYGSSICAQQE 257
Cdd:TIGR01122 92 VFRGDGDLGLnpRAGYKPDVIIAAWPWGAYLGEEALEKgidakVSSWrrNAPNTI------PTAAKAGGNYLNSLLAKSE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 258 ALELGCQQVLWLyGEDHQITEVGTMNLFlywINEDGenELATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDL 337
Cdd:TIGR01122 166 ARRHGYDEAILL-DVEGYVAEGSGENIF---IVKDG--VLFTPPVTSSILPGITRDTVITLAKELG-IEVVEQPISREEL 238
|
250 260
....*....|....*....|....*..
gi 2024449537 338 TAAleenrvKEMFGAGTACIVCPISKI 364
Cdd:TIGR01122 239 YTA------DEAFFTGTAAEITPIREV 259
|
|
| D-AAT_like |
cd01558 |
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes ... |
116-364 |
3.26e-23 |
|
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and D-glutamate in addition to other D-amino acids. The enzyme like other members of this superfamily requires PLP as a cofactor. Members of this subgroup are found in all three forms of life.
Pssm-ID: 238799 [Multi-domain] Cd Length: 270 Bit Score: 98.05 E-value: 3.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 116 FEGMKAYRGvdgkiRLFRPSLNMDRMARSAR--RMTLPcFDQNELLECIRKLVEVEKewvpySTAASLYIRPTLiGTEP- 192
Cdd:cd01558 28 YEVIRVYNG-----KPFALDEHLDRLYRSAKelRIDIP-YTREELKELIRELVAKNE-----GGEGDVYIQVTR-GVGPr 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 193 SLGVKKPTKALLYVILSPVGAYFSSECFNPISLWADPkyVRAWkggtGDCKL-GGNYGSSICAQQEALELGCQQVlWLYG 271
Cdd:cd01558 96 GHDFPKCVKPTVVIITQPLPLPPAELLEKGVRVITVP--DIRW----LRCDIkSLNLLNNVLAKQEAKEAGADEA-ILLD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 272 EDHQITEVGTMNLFlywINEDGEneLATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAleenrvKEMFG 351
Cdd:cd01558 169 ADGLVTEGSSSNVF---IVKNGV--LVTPPLDNGILPGITRATVIELAKELG-IPVEERPFSLEELYTA------DEVFL 236
|
250
....*....|...
gi 2024449537 352 AGTACIVCPISKI 364
Cdd:cd01558 237 TSTTAEVMPVVEI 249
|
|
| ADCL_like |
cd01559 |
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent ... |
108-342 |
4.63e-18 |
|
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.
Pssm-ID: 238800 [Multi-domain] Cd Length: 249 Bit Score: 83.13 E-value: 4.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 108 SLHYATELFEGMKAYRGvdgkiRLFRPSLNMDRMARSARRMTLPCFDQNELLECIRKLVEVekewvpySTAASLYIRPTL 187
Cdd:cd01559 3 GFAYGDGVFETMRALDG-----RLFLLDAHLARLERSARRLGIPEPDLPRLRAALESLLAA-------NDIDEGRIRLIL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 188 I-GTEP----SLGVKKPTkalLYVilsPVGAYFSSECFNPISLWADPkyVRAWKGGTgdckLGG----NYGSSICAQQEA 258
Cdd:cd01559 71 SrGPGGrgyaPSVCPGPA---LYV---SVIPLPPAWRQDGVRLITCP--VRLGEQPL----LAGlkhlNYLENVLAKREA 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 259 LELGCQQVLWLYGEDHqITEVGTMNLFlyWINEdgeNELATPPLDGIILPGVTRQSILDLARNWGEfKVSERYITMSDLT 338
Cdd:cd01559 139 RDRGADEALFLDTDGR-VIEGTASNLF--FVKD---GELVTPSLDRGGLAGITRQRVIELAAAKGY-AVDERPLRLEDLL 211
|
....
gi 2024449537 339 AALE 342
Cdd:cd01559 212 AADE 215
|
|
| PRK07544 |
PRK07544 |
branched-chain amino acid aminotransferase; Validated |
109-364 |
1.69e-12 |
|
branched-chain amino acid aminotransferase; Validated
Pssm-ID: 181025 Cd Length: 292 Bit Score: 67.31 E-value: 1.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 109 LHYATELFEGMKAYrgvDGKIrlFRPSLNMDRMARSARRM--TLPcFDQNELLECIRKLVEVekewvpySTAASLYIRPT 186
Cdd:PRK07544 32 LHYASSVFEGERAY---GGKI--FKLREHSERLRRSAELLdfEIP-YSVAEIDAAKKETLAA-------NGLTDAYVRPV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 187 L-IGTEpSLGVKKP-TKALLYVILSPVGAYFSSEC-FNPISL----WA--DPKyvrawkggTGDC--KLGGNYgsSIC-- 253
Cdd:PRK07544 99 AwRGSE-MMGVSAQqNKIHLAIAAWEWPSYFDPEAkMKGIRLdiakWRrpDPE--------TAPSaaKAAGLY--MICti 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 254 AQQEALELGCQQVLWLygeDH--QITEVGTMNLFLYwinEDGenELATPPLDgIILPGVTRQSILDLARNWGeFKVSERY 331
Cdd:PRK07544 168 SKHAAEAKGYADALML---DYrgYVAEATGANIFFV---KDG--VIHTPTPD-CFLDGITRQTVIELAKRRG-IEVVERH 237
|
250 260 270
....*....|....*....|....*....|...
gi 2024449537 332 ITMSDLTAAleenrvKEMFGAGTACIVCPISKI 364
Cdd:PRK07544 238 IMPEELAGF------SECFLTGTAAEVTPVSEI 264
|
|
| PRK08320 |
PRK08320 |
branched-chain amino acid aminotransferase; Reviewed |
116-364 |
3.03e-12 |
|
branched-chain amino acid aminotransferase; Reviewed
Pssm-ID: 236238 [Multi-domain] Cd Length: 288 Bit Score: 66.82 E-value: 3.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 116 FEGMKAYRGvdgkiRLFRPSLNMDRMARSAR--RMTLPcFDQNELLECIRKLVEVEKewvpYSTAaslYIRPTLIGTEPS 193
Cdd:PRK08320 33 FEGIRAYNG-----RVFRLKEHIDRLYDSAKaiMLEIP-LSKEEMTEIVLETLRKNN----LRDA---YIRLVVSRGVGD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 194 LGV--KKPTKALLYVILSPVGAYF------------------SSECFNP--ISLwadpkyvrawkggtgdcklggNYGSS 251
Cdd:PRK08320 100 LGLdpRKCPKPTVVCIAEPIGLYPgelyekglkvitvstrrnRPDALSPqvKSL---------------------NYLNN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 252 ICAQQEALELGCQQVLWLygeDHQ--ITEVGTMNLFLYwinEDGEneLATPPLDGIILPGVTRQSILDLARNWGeFKVSE 329
Cdd:PRK08320 159 ILAKIEANLAGVDEAIML---NDEgyVAEGTGDNIFIV---KNGK--LITPPTYAGALEGITRNAVIEIAKELG-IPVRE 229
|
250 260 270
....*....|....*....|....*....|....*
gi 2024449537 330 RYITMSDLTAAleenrvKEMFGAGTACIVCPISKI 364
Cdd:PRK08320 230 ELFTLHDLYTA------DEVFLTGTAAEVIPVVKV 258
|
|
| PRK06680 |
PRK06680 |
D-amino acid aminotransferase; Reviewed |
254-364 |
1.32e-08 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 180656 [Multi-domain] Cd Length: 286 Bit Score: 55.71 E-value: 1.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 254 AQQEALELGCQQVlWlYGEDHQITEVGTMNlflYWInEDGENELATPPLDGIILPGVTRQSILDLARNWGeFKVSERYIT 333
Cdd:PRK06680 159 AKQAAKEAGAQEA-W-MVDDGFVTEGASSN---AWI-VTKDGKLVTRPADNFILPGITRHTLIDLAKELG-LEVEERPFT 231
|
90 100 110
....*....|....*....|....*....|.
gi 2024449537 334 MSDLTAAleenrvKEMFGAGTACIVCPISKI 364
Cdd:PRK06680 232 LQEAYAA------REAFITAASSFVFPVVQI 256
|
|
| PRK13356 |
PRK13356 |
branched-chain amino acid aminotransferase; |
112-364 |
2.55e-08 |
|
branched-chain amino acid aminotransferase;
Pssm-ID: 237362 Cd Length: 286 Bit Score: 54.96 E-value: 2.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 112 ATELFEGMKAYRGVdgkirlfRPSLNM--DRMARSARRMTL-PCFDQNELLECIRKLVEvekewvPYSTAASLYIRPTLI 188
Cdd:PRK13356 33 GSTVFDGARAFEGV-------TPDLDLhcARVNRSAEALGLkPTVSAEEIEALAREGLK------RFDPDTALYIRPMYW 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 189 GTEPSLGVKKP----TK-AL-LYVILSPVGAYFSSeCFNPislwadpkYVRAW-KGGTGDCKLGGNYGSSICAQQEALEL 261
Cdd:PRK13356 100 AEDGFASGVAPdpesTRfALcLEEAPMPEPTGFSL-TLSP--------FRRPTlEMAPTDAKAGCLYPNNARALREARSR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 262 GCQQVLWLYGEDHqITEVGTMNLFlywINEDGEneLATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAAl 341
Cdd:PRK13356 171 GFDNALVLDMLGN-VAETATSNVF---MVKDGV--VFTPVPNGTFLNGITRQRVIALLREDG-VTVVETTLTYEDFLEA- 242
|
250 260
....*....|....*....|...
gi 2024449537 342 eenrvKEMFGAGTACIVCPISKI 364
Cdd:PRK13356 243 -----DEVFSTGNYSKVVPVTRF 260
|
|
| PRK07849 |
PRK07849 |
aminodeoxychorismate lyase; |
125-340 |
3.80e-08 |
|
aminodeoxychorismate lyase;
Pssm-ID: 236114 [Multi-domain] Cd Length: 292 Bit Score: 54.19 E-value: 3.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 125 VDGKIRLFRPSLnmDRMARSARRMTLPCFDQNELLECIRKLVEvekEWvpYSTAASLYIRPTLigtepSLGVKKPTKALL 204
Cdd:PRK07849 48 RDGRPCNLEAHL--ERLARSAALLDLPEPDLDRWRRAVELAIE---EW--RAPEDEAALRLVY-----SRGRESGGAPTA 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 205 YVILSPVGAYFSSECFNPISLWADPkyvRAWKGGTGDCK---LGG----NYGSSICAQQEALELGCQQVLWLyGEDHQIT 277
Cdd:PRK07849 116 WVTVSPVPERVARARREGVSVITLD---RGYPSDAAERApwlLAGaktlSYAVNMAALRYAARRGADDVIFT-STDGYVL 191
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024449537 278 EVGTMNLFLYwinEDGEneLATPPLDGIILPGVTRQSILDLARNWGeFKVSERYITMSDLTAA 340
Cdd:PRK07849 192 EGPTSTVVIA---TDDR--LLTPPPWYGILPGTTQAALFEVAREKG-WDCEYRALRPADLFAA 248
|
|
| PRK12400 |
PRK12400 |
D-amino acid aminotransferase; Reviewed |
109-379 |
4.47e-06 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 171470 Cd Length: 290 Bit Score: 48.09 E-value: 4.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 109 LHYATELFEGMKAYRGvdgKIRLFRPSLNmdRMARSARR--MTLPcFDQNELLECIRKLVEVEKewvpYSTAASLYIrpt 186
Cdd:PRK12400 30 LQFGDGVYEVIRLYKG---NFHLLDPHIT--RLYRSMEEieLTLP-FSKAELITLLYKLIENNN----FHEDGTIYL--- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 187 ligtEPSLGVKKPTKALLYVILSPVGAYFSSEcfNPISLW----------ADPKYVRawkggtgdCKLGG-NYGSSICAQ 255
Cdd:PRK12400 97 ----QVSRGVQARTHTFSYDVPPTIYAYITKK--ERPALWieygvraisePDTRWLR--------CDIKSlNLLPNILAA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 256 QEALELGCQQVLWLygEDHQITEVGTMNLFLYwinEDGEneLATPPLDGIILPGVTRQSILDLArNWGEFKVSERYITMS 335
Cdd:PRK12400 163 TKAERKGCKEALFV--RNGTVTEGSHSNFFLI---KNGT--LYTHPANHLILNGIIRQYVLSLA-KTLRIPVQEELFSVR 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2024449537 336 DLTAAleenrvKEMFGAGTACIVCPISkilykgkHLHIPTMENG 379
Cdd:PRK12400 235 DVYQA------DECFFTGTTIEILPMT-------HLDGTAIQDG 265
|
|
| PRK07546 |
PRK07546 |
hypothetical protein; Provisional |
269-340 |
3.31e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 169002 [Multi-domain] Cd Length: 209 Bit Score: 44.58 E-value: 3.31e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024449537 269 LYGEDHQITEVGTMNLFLywinEDGENELATPPLDGIILPGVTRQSILDlarnwgEFKVSERYITMSDLTAA 340
Cdd:PRK07546 130 LLNERGEVCEGTITNVFL----DRGGGMLTTPPLSCGLLPGVLRAELLD------AGRAREAVLTVDDLKSA 191
|
|
| PLN02845 |
PLN02845 |
Branched-chain-amino-acid aminotransferase-like protein |
247-361 |
1.37e-04 |
|
Branched-chain-amino-acid aminotransferase-like protein
Pssm-ID: 215454 [Multi-domain] Cd Length: 336 Bit Score: 43.46 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 247 NYGSSICAQQEALELGCQQVLWLyGEDHQITEVGTMNL-FLywineDGENELATPPLDGIiLPGVTRQSILDLA---RNW 322
Cdd:PLN02845 188 NYLPNALSQMEAEERGAFAGIWL-DEEGFVAEGPNMNVaFL-----TNDGELVLPPFDKI-LSGCTARRVLELAprlVSP 260
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2024449537 323 GEFK-VSERYITMSDLTAAleenrvKEMFGAGTACIVCPI 361
Cdd:PLN02845 261 GDLRgVKQRKISVEEAKAA------DEMMLIGSGVPVLPI 294
|
|
| PRK12479 |
PRK12479 |
branched-chain-amino-acid transaminase; |
247-364 |
2.58e-03 |
|
branched-chain-amino-acid transaminase;
Pssm-ID: 183549 [Multi-domain] Cd Length: 299 Bit Score: 39.55 E-value: 2.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024449537 247 NYGSSICAQQEALELGCQQVLWLyGEDHQITEVGTMNLFlywINEDGEneLATPPLDGIILPGVTRQSILDLARNWGeFK 326
Cdd:PRK12479 155 NYLNNVLVKIEAAQAGVLEALML-NQQGYVCEGSGDNVF---VVKDGK--VLTPPSYLGALEGITRNSVIELCERLS-IP 227
|
90 100 110
....*....|....*....|....*....|....*...
gi 2024449537 327 VSERYITMSDLTAAleenrvKEMFGAGTACIVCPISKI 364
Cdd:PRK12479 228 CEERPFTRHDVYVA------DEVFLTGTAAELIPVVKV 259
|
|
| |
