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Conserved domains on  [gi|2024469763|ref|XP_040519601|]
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golgin subfamily A member 4 isoform X5 [Gallus gallus]

Protein Classification

kinesin family protein; PEPP family PH domain-containing protein( domain architecture ID 13278977)

kinesin family protein is a microtubule-dependent molecular motor that plays an important role in intracellular transport and in cell division and has ATPase-containing motor domain; similar to carboxy-terminal kinesins that contains a C-terminal domain responsible for the motor activity (it hydrolyzes ATP and binds microtubules)| PEPP (phosphoinositol 3-phosphate-binding protein) family PH (pleckstrin homology) domain-containing protein similar to PH domain region of vertebrate pleckstrin homology domain-containing family A member 4/5/6/7

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 803-1710 9.29e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 9.29e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  803 SLSQQNTSNEQAKQYEEELAKLQQKLmdLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENtqkam 882
Cdd:TIGR02168  204 SLERQAEKAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----- 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  883 sltqqyeSQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERIStlqgdyenKLKRQENKMEKMKQK 962
Cdd:TIGR02168  277 -------SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE--------ELESKLDELAEELAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  963 SKEMQETFKKKLAEQESKLKkELENKQLEFSQKESEFNAKMLEMAhassAGINDAVSKLESNQKE------QLESLAEAH 1036
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELE-ELEAELEELESRLEELEEQLETLR----SKVAQLELQIASLNNEierleaRLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1037 KRELEEISRSWEKKLNQQAEELQekheMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELK 1116
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQ----AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1117 QSLAQMSALSNSESGLKAQLQKLEGdlsqslkeKSGLQEQISRQKAIEEKDKARIteladkLKTLEEKLQTLQSshskDR 1196
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSG--------LSGILGVLSELISVDEGYEAAI------EAALGGRLQAVVV----EN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1197 ENYEKKIEAFQQQETEVKELVAQLDaywksaeVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKS-- 1274
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELGRVTFLPLD-------SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1275 VQQLQEKDNVIKSMRDDiEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKT 1354
Cdd:TIGR02168  628 VDDLDNALELAKKLRPG-YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1355 INELNVRLEsmvSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVdhctAKLSEWKTKAQTRFTQ 1434
Cdd:TIGR02168  707 LEELEEELE---QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI----EELEERLEEAEEELAE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1435 NHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTaELKIQAARVAELEEHIA 1514
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE-DLEEQIEELSEDIESLA 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1515 QKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAI 1594
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1595 lkskeeelKELEERLNAENSCKLADLKKKAEQKIGSIkRELVRQMEEKEQQLKQ------DRENQVRHLEQKVQEREAKI 1668
Cdd:TIGR02168  939 --------DNLQERLSEEYSLTLEEAEALENKIEDDE-EEARRRLKRLENKIKElgpvnlAAIEEYEELKERYDFLTAQK 1009

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|...
gi 2024469763 1669 ESLEEKMKSVRDS-TELEREMLQKIESTKAAVEQEKNEVIKSV 1710
Cdd:TIGR02168 1010 EDLTEAKETLEEAiEEIDREARERFKDTFDQVNENFQRVFPKL 1052
PTZ00121 super family cl31754
MAEBL; Provisional
 1420-2022 3.83e-17

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 88.66  E-value: 3.83e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1420 KLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEEL--AQQGKDLDSLKSVLEEKENRIEKQESELTA 1497
Cdd:PTZ00121  1195 KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1498 ELKIQAARVAELEEhiAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQ-AEKVAFEKDSRLKEAEEKVLNLENEIGSL 1576
Cdd:PTZ00121  1275 EEARKADELKKAEE--KKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKkAEEAKKKADAAKKKAEEAKKAAEAAKAEA 1352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1577 KAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQ---KIGSIKRELVRQMEEKEQQLKQDRENQ 1653
Cdd:PTZ00121  1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkkKADELKKAAAAKKKADEAKKKAEEKKK 1432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1654 VRHLEQKVQEREaKIESLEEKMKSVRDSTELEREMLQKI---ESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNK 1730
Cdd:PTZ00121  1433 ADEAKKKAEEAK-KADEAKKKAEEAKKAEEAKKKAEEAKkadEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1731 LLQKYESEQREGIDSLLELQSKQE-ELLKKLEcaEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLAssrEEL 1809
Cdd:PTZ00121  1512 ADEAKKAEEAKKADEAKKAEEAKKaDEAKKAE--EKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA---EEA 1586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1810 KAKEQKNLGMENIMGDFQKKMQEKDAVShslEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKA 1889
Cdd:PTZ00121  1587 KKAEEARIEEVMKLYEEEKKMKAEEAKK---AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA 1663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1890 LEE--NAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAeREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQ 1967
Cdd:PTZ00121  1664 AEEakKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA-KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1968 KIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIE 2022
Cdd:PTZ00121  1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
PTZ00121 super family cl31754
MAEBL; Provisional
 274-1090 4.39e-16

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.19  E-value: 4.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  274 EDSVKTLETLNQRVKRQEnllQRCKEMIRSHKERCAQLTNEKEALQEQLEE--RLQELEKMKDLHMGEKTKLITQLRDAK 351
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEE---AKKTETGKAEEARKAEEAKKKAEDARKAEEarKAEDARKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  352 NL--IEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELK-EQKEKFERAA-FEELEKALGMAQRTEE 427
Cdd:PTZ00121  1162 DArkAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKaEEARKAEDAKkAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  428 ARKKLQTEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAelEKLHKEEMATKDQELNERLQAQEREFQ 507
Cdd:PTZ00121  1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA--DEAKKAEEKKKADEAKKKAEEAKKADE 1319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  508 EKMKAALEKNQSECLKTLQEQEQQESL--ALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKR 585
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEaaKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  586 SEELSTLMDS-EKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKlqilqqqhviEIEKMREKQEQEIDTILKEKETVFR 664
Cdd:PTZ00121  1400 AEEDKKKADElKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK----------KADEAKKKAEEAKKAEEAKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  665 THIEEMNEKTLEKLDVKQTEletlssELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEveimlKEHEI 744
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKADEAK------KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA-----KKADE 1538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  745 SIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSAR----LMEASLSQQNTSNEQAKQYEEE 820
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEArieeVMKLYEEEKKMKAEEAKKAEEA 1618

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  821 LAKLQQ--KLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSD--ENTQKAMSLTQQYESQLKDLQ 896
Cdd:PTZ00121  1619 KIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKkaEEAKKAEEDEKKAAEALKKEA 1698

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  897 EEADKAKQTLTERENDIEHVKKVQNEE------MEELKQKLLATEERISTLQGDYENKLKRQENKmekmKQKSKEMQETF 970
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEKKKAEELKKAEeenkikAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLK----KEEEKKAEEIR 1774

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  971 KKKLAEQESKLKKELENKQLEFSQKESEF---NAKMLEMAHASSAGINDAVSKLESNQKE-------QLESLAEAHKREL 1040
Cdd:PTZ00121  1775 KEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKEGNLVINDSKEMEDSAIKEvadsknmQLEEADAFEKHKF 1854

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1041 EEISRSWEKKlNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGS 1090
Cdd:PTZ00121  1855 NKNNENGEDG-NKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIP 1903
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2162-2205 7.40e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.30  E-value: 7.40e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 2024469763  2162 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPADQTQKILER 2205
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
MukB super family cl34550
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 134-387 2.31e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG3096:

Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.48  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  134 EQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQ----SQDKALRRIGELREELQMDQQAKKHLQEeFDA 209
Cdd:COG3096    839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQanllADETLADRLEELREELDAAQEAQAFIQQ-HGK 917

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  210 SLEEKDQLISVLQT---QVSLLKQRLQngqigielpdpnnQSEPQVQSQTKEINA-ENIVEPGSNEGNEDSVKTL----- 280
Cdd:COG3096    918 ALAQLEPLVAVLQSdpeQFEQLQADYL-------------QAKEQQRRLKQQIFAlSEVVQRRPHFSYEDAVGLLgensd 984

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  281 --ETLNQRVKRQENLLQRCKEMIRSHKERCAQ-------LTNEKEALQEQLEERLQELEKM--------KDLHMGEKTKL 343
Cdd:COG3096    985 lnEKLRARLEQAEEARREAREQLRQAQAQYSQynqvlasLKSSRDAKQQTLQELEQELEELgvqadaeaEERARIRRDEL 1064

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 2024469763  344 ITQLRDAKNLIEQLEQDKGMVIAETKrQMHETLEMKEEEVAQLR 387
Cdd:COG3096   1065 HEELSQNRSRRSQLEKQLTRCEAEMD-SLQKRLRKAERDYKQER 1107
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 803-1710 9.29e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 9.29e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  803 SLSQQNTSNEQAKQYEEELAKLQQKLmdLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENtqkam 882
Cdd:TIGR02168  204 SLERQAEKAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----- 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  883 sltqqyeSQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERIStlqgdyenKLKRQENKMEKMKQK 962
Cdd:TIGR02168  277 -------SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE--------ELESKLDELAEELAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  963 SKEMQETFKKKLAEQESKLKkELENKQLEFSQKESEFNAKMLEMAhassAGINDAVSKLESNQKE------QLESLAEAH 1036
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELE-ELEAELEELESRLEELEEQLETLR----SKVAQLELQIASLNNEierleaRLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1037 KRELEEISRSWEKKLNQQAEELQekheMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELK 1116
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQ----AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1117 QSLAQMSALSNSESGLKAQLQKLEGdlsqslkeKSGLQEQISRQKAIEEKDKARIteladkLKTLEEKLQTLQSshskDR 1196
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSG--------LSGILGVLSELISVDEGYEAAI------EAALGGRLQAVVV----EN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1197 ENYEKKIEAFQQQETEVKELVAQLDaywksaeVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKS-- 1274
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELGRVTFLPLD-------SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1275 VQQLQEKDNVIKSMRDDiEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKT 1354
Cdd:TIGR02168  628 VDDLDNALELAKKLRPG-YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1355 INELNVRLEsmvSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVdhctAKLSEWKTKAQTRFTQ 1434
Cdd:TIGR02168  707 LEELEEELE---QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI----EELEERLEEAEEELAE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1435 NHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTaELKIQAARVAELEEHIA 1514
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE-DLEEQIEELSEDIESLA 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1515 QKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAI 1594
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1595 lkskeeelKELEERLNAENSCKLADLKKKAEQKIGSIkRELVRQMEEKEQQLKQ------DRENQVRHLEQKVQEREAKI 1668
Cdd:TIGR02168  939 --------DNLQERLSEEYSLTLEEAEALENKIEDDE-EEARRRLKRLENKIKElgpvnlAAIEEYEELKERYDFLTAQK 1009

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|...
gi 2024469763 1669 ESLEEKMKSVRDS-TELEREMLQKIESTKAAVEQEKNEVIKSV 1710
Cdd:TIGR02168 1010 EDLTEAKETLEEAiEEIDREARERFKDTFDQVNENFQRVFPKL 1052
PTZ00121 PTZ00121
MAEBL; Provisional
 1420-2022 3.83e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 88.66  E-value: 3.83e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1420 KLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEEL--AQQGKDLDSLKSVLEEKENRIEKQESELTA 1497
Cdd:PTZ00121  1195 KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1498 ELKIQAARVAELEEhiAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQ-AEKVAFEKDSRLKEAEEKVLNLENEIGSL 1576
Cdd:PTZ00121  1275 EEARKADELKKAEE--KKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKkAEEAKKKADAAKKKAEEAKKAAEAAKAEA 1352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1577 KAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQ---KIGSIKRELVRQMEEKEQQLKQDRENQ 1653
Cdd:PTZ00121  1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkkKADELKKAAAAKKKADEAKKKAEEKKK 1432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1654 VRHLEQKVQEREaKIESLEEKMKSVRDSTELEREMLQKI---ESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNK 1730
Cdd:PTZ00121  1433 ADEAKKKAEEAK-KADEAKKKAEEAKKAEEAKKKAEEAKkadEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1731 LLQKYESEQREGIDSLLELQSKQE-ELLKKLEcaEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLAssrEEL 1809
Cdd:PTZ00121  1512 ADEAKKAEEAKKADEAKKAEEAKKaDEAKKAE--EKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA---EEA 1586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1810 KAKEQKNLGMENIMGDFQKKMQEKDAVShslEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKA 1889
Cdd:PTZ00121  1587 KKAEEARIEEVMKLYEEEKKMKAEEAKK---AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA 1663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1890 LEE--NAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAeREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQ 1967
Cdd:PTZ00121  1664 AEEakKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA-KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1968 KIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIE 2022
Cdd:PTZ00121  1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1458-2137 4.09e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 4.09e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1458 EELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDME 1537
Cdd:TIGR02168  186 ENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1538 QKevawQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENscKL 1617
Cdd:TIGR02168  266 EE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE--EL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1618 ADLKKKAEQKigSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRdsTELEReMLQKIESTKA 1697
Cdd:TIGR02168  340 AELEEKLEEL--KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN--NEIER-LEARLERLED 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1698 AVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQS---VT 1774
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArldSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1775 EGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMG---------DFQKKMQEKDAVSHSLEQKVK 1845
Cdd:TIGR02168  495 ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGgrlqavvveNLNAAKKAIAFLKQNELGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1846 ELEDNLAKVNEVHKTEMEdrSLKYEENLKSLQQQLEERNDRLKALEEN-------------------------------- 1893
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDRE--ILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvvddldnalelakklrpgyrivtldg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1894 ------------AEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVK--K 1959
Cdd:TIGR02168  653 dlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISalR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1960 ESLEEMEQKIRCEQEDIELKHSSTLKQLMREfnTQLAQKEMELETAVKETISKAQEVEsELIENHQIETTQLHKKIAEKD 2039
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEI--EELEERLEEAEEELAEAEAEIEELE-AQIEQLKEELKALREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2040 DDLKRTVKKYeEILEAREEEMTTKVHELQTQLEELQKEYKQRMAE----KDHRNSENVTIAELQAQLAQKTTLVNDSKLK 2115
Cdd:TIGR02168  810 AELTLLNEEA-ANLRERLESLERRIAATERRLEDLEEQIEELSEDieslAAEIEELEELIEELESELEALLNERASLEEA 888

                          730       740
                   ....*....|....*....|..
gi 2024469763 2116 EQEFKEQIHVLEDRLKNYEKKM 2137
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKR 910
PTZ00121 PTZ00121
MAEBL; Provisional
 274-1090 4.39e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.19  E-value: 4.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  274 EDSVKTLETLNQRVKRQEnllQRCKEMIRSHKERCAQLTNEKEALQEQLEE--RLQELEKMKDLHMGEKTKLITQLRDAK 351
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEE---AKKTETGKAEEARKAEEAKKKAEDARKAEEarKAEDARKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  352 NL--IEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELK-EQKEKFERAA-FEELEKALGMAQRTEE 427
Cdd:PTZ00121  1162 DArkAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKaEEARKAEDAKkAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  428 ARKKLQTEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAelEKLHKEEMATKDQELNERLQAQEREFQ 507
Cdd:PTZ00121  1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA--DEAKKAEEKKKADEAKKKAEEAKKADE 1319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  508 EKMKAALEKNQSECLKTLQEQEQQESL--ALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKR 585
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEaaKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  586 SEELSTLMDS-EKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKlqilqqqhviEIEKMREKQEQEIDTILKEKETVFR 664
Cdd:PTZ00121  1400 AEEDKKKADElKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK----------KADEAKKKAEEAKKAEEAKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  665 THIEEMNEKTLEKLDVKQTEletlssELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEveimlKEHEI 744
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKADEAK------KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA-----KKADE 1538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  745 SIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSAR----LMEASLSQQNTSNEQAKQYEEE 820
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEArieeVMKLYEEEKKMKAEEAKKAEEA 1618

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  821 LAKLQQ--KLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSD--ENTQKAMSLTQQYESQLKDLQ 896
Cdd:PTZ00121  1619 KIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKkaEEAKKAEEDEKKAAEALKKEA 1698

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  897 EEADKAKQTLTERENDIEHVKKVQNEE------MEELKQKLLATEERISTLQGDYENKLKRQENKmekmKQKSKEMQETF 970
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEKKKAEELKKAEeenkikAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLK----KEEEKKAEEIR 1774

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  971 KKKLAEQESKLKKELENKQLEFSQKESEF---NAKMLEMAHASSAGINDAVSKLESNQKE-------QLESLAEAHKREL 1040
Cdd:PTZ00121  1775 KEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKEGNLVINDSKEMEDSAIKEvadsknmQLEEADAFEKHKF 1854

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1041 EEISRSWEKKlNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGS 1090
Cdd:PTZ00121  1855 NKNNENGEDG-NKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIP 1903
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 367-1188 4.62e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.11  E-value: 4.62e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  367 ETKRQMHETlemkEEEVAQLRARIKQITTQGEELKEQKEKFER-----AAFEELEKALgMAQRTEEARKKLqtemdEKIK 441
Cdd:TIGR02168  176 ETERKLERT----RENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELAL-LVLRLEELREEL-----EELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  442 AVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRvAELEKLHKEEMATKdqELNERLQAQEREFQEKMKAaLEKNQSEC 521
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLEVSELE-EEIEELQKELYALA--NEISRLEQQKQILRERLAN-LERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  522 LKTLQEQEQQESLALEELELQKKAIQS------ECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMdS 595
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEElkeeleSLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-N 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  596 EKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQhVIEIEKMREKQEQEIDTILKEKETvfrthIEEMNEKTL 675
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE-LEELEEELEELQEELERLEEALEE-----LREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  676 EKLDVKQTELETLSSELsEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAE------RNQHKEEVEIMLKEH------- 742
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLselisvDEGYEAAIEAALGGRlqavvve 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  743 --EISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELK--ESAQRSEAELVQVSARL---MEASLSQ------QNT 809
Cdd:TIGR02168  554 nlNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLrkaLSYLLGGvlvvddLDN 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  810 SNEQAKQYEEElaklqQKLMDLKGEKLQ----LSEQLVRTECQLNEVKNELElyisqvhELKQQLQEQSDENTQKAMSLt 885
Cdd:TIGR02168  634 ALELAKKLRPG-----YRIVTLDGDLVRpggvITGGSAKTNSSILERRREIE-------ELEEKIEELEEKIAELEKAL- 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  886 QQYESQLKDLQEEADKAKQTLTERENDIehvkkvqnEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKE 965
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQI--------SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  966 MQETFKKKLAEQEsKLKKELENKQLEFSQKESEFNAKMLEmAHASSAGINDAVSKLESNQKEqleslAEAHKRELEEISR 1045
Cdd:TIGR02168  773 AEEELAEAEAEIE-ELEAQIEQLKEELKALREALDELRAE-LTLLNEEAANLRERLESLERR-----IAATERRLEDLEE 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1046 SWEkklnqQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSAL 1125
Cdd:TIGR02168  846 QIE-----ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1126 SNSESGLKAQLQKLEGDLsQSLKEKSGLQEQISRQKAIE--EKDKARITELADKLKTLEEKLQTL 1188
Cdd:TIGR02168  921 REKLAQLELRLEGLEVRI-DNLQERLSEEYSLTLEEAEAleNKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 278-831 5.90e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 5.90e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  278 KTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEkmkdLHMGEKTKLITQLRDAKNLIEQL 357
Cdd:COG1196    239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY----ELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  358 EQDkgmvIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMD 437
Cdd:COG1196    315 EER----LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  438 EKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKN 517
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  518 QSEclktLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRIL--ELESSLAKCSQDDKKRSEELSTLMDS 595
Cdd:COG1196    471 EAA----LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrGLAGAVAVLIGVEAAYEAALEAALAA 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  596 EKKQHNKEVSDIVEKHKEEL-ENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKT 674
Cdd:COG1196    547 ALQNIVVEDDEVAAAAIEYLkAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  675 LEKLDVKQTELetLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLK 754
Cdd:COG1196    627 LVAARLEAALR--RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763  755 EELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQvsARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDL 831
Cdd:COG1196    705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE--EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1439-1966 5.42e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 5.42e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1439 IKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELtAELKIQAARVAELEEHIAQKTS 1518
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE-YELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1519 ENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSK 1598
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1599 EEELKELEERLNAENSCK-LADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAK--IESLEEKM 1675
Cdd:COG1196    393 RAAAELAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLelLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1676 KSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQ-- 1753
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNiv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1754 -EELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQE 1832
Cdd:COG1196    553 vEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1833 KDAVSHSLEQKVKELEDNLAkvnevhKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQ 1912
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLE------GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE 706

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024469763 1913 NQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEME 1966
Cdd:COG1196    707 RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1458-2020 2.42e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 2.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1458 EELDKLK-EELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELkrYHEQKDM 1536
Cdd:COG1196    220 EELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE--YELLAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1537 EQKEVAWQLQQAekvafekdsRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENscK 1616
Cdd:COG1196    298 ARLEQDIARLEE---------RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE--A 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1617 LADLKKKAEQKIGSIKRELVRQMEEKEQQLKQdrENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTK 1696
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAEL--AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1697 AAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEG 1776
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1777 LREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQ----KKMQEKDAVSHSLEQKVKELEDNLA 1852
Cdd:COG1196    525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflplDKIRARAALAAALARGAIGAAVDLV 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1853 KVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKL 1932
Cdd:COG1196    605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1933 RKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHsstLKQLMREFNTQLAQKEMELETAVKETISK 2012
Cdd:COG1196    685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA---EREELLEELLEEEELLEEEALEELPEPPD 761


                   ....*...
gi 2024469763 2013 AQEVESEL 2020
Cdd:COG1196    762 LEELEREL 769
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 399-1186 6.72e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.07  E-value: 6.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  399 ELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVA 478
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  479 ELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSEC---LKTLQEQEQQESLALEELELQKKAIQSECDKKLE 555
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLakeEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  556 EMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNkevsdIVEKHKEELENVKQQQEKLWTEKLQILQQ 635
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEE-----LLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  636 QHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGE 715
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  716 AKQE--FEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELV 793
Cdd:pfam02463  484 EQLEllLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  794 QVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEqlvRTECQLNEVKNELELYISQVHELKQQLQEQ 873
Cdd:pfam02463  564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK---ATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  874 SDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQE 953
Cdd:pfam02463  641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  954 NKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLA 1033
Cdd:pfam02463  721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1034 EAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQE 1113
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024469763 1114 ELKQSLAQMSALSNSESGLKAQLQKLEGDLSQsLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQ 1186
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLL-EEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEE 952
PTZ00121 PTZ00121
MAEBL; Provisional
 734-1470 7.44e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.78  E-value: 7.44e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  734 EVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQvsaRLMEASLSQQNTSNEQ 813
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR---KAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  814 AKQYEE-ELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQL 892
Cdd:PTZ00121  1157 ARKAEDaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAK 1236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  893 KDlQEEADKAkqtltERENDIEHVKKVQNEEMEELKQKLL---ATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQET 969
Cdd:PTZ00121  1237 KD-AEEAKKA-----EEERNNEEIRKFEEARMAHFARRQAaikAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  970 FKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEK 1049
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1050 KLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSE 1129
Cdd:PTZ00121  1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1130 SGLKAQLQKLEGDLSQSLKEKSglqeQISRQKAIEEKDKARITELADKLKTLEEKlqtLQSSHSKDRENYEKKIEAFQQQ 1209
Cdd:PTZ00121  1471 KADEAKKKAEEAKKADEAKKKA----EEAKKKADEAKKAAEAKKKADEAKKAEEA---KKADEAKKAEEAKKADEAKKAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1210 ETEVKELVAQLDAYWKSAEVllqtKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMR 1289
Cdd:PTZ00121  1544 EKKKADELKKAEELKKAEEK----KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1290 DDIEGLVTEKEQLQKEGGHQKQAATEKETCiTQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLT 1369
Cdd:PTZ00121  1620 IKAEELKKAEEEKKKVEQLKKKEAEEKKKA-EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1370 EKEAAISLLSTQHQEERlqlinqvqelsSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVS 1449
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEK-----------KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767

                          730       740
                   ....*....|....*....|.
gi 2024469763 1450 NTQATKKGEELDKLKEELAQQ 1470
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEELDEE 1788
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1017-1904 1.17e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.84  E-value: 1.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1017 AVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITR 1096
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1097 LKEEQVKRNETLKQLQEELKQslAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELAD 1176
Cdd:pfam02463  243 QELLRDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1177 KLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDaywksaEVLLQTKSNELIEKCNEKIGIVTCKIADC 1256
Cdd:pfam02463  321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQ------EKLEQLEEELLAKKKLESERLSSAAKLKE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1257 ERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTS 1336
Cdd:pfam02463  395 EELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1337 LREDLQEKESEISTLNKTINElnvRLESMVSLTEKEAAISLLSTQHQEERLQLInqvqelSSSVELLRQEKASALEQVDH 1416
Cdd:pfam02463  475 KETQLVKLQEQLELLLSRQKL---EERSQKESKARSGLKVLLALIKDGVGGRII------SAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1417 CTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVsntqATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELT 1496
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGA----RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1497 AELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSL 1576
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1577 KAECEAKEREFDQMKSAILKSKEEELKELEERLNAEnsckLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRH 1656
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEELLADRVQEAQDKINEE----LKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1657 LEQKVQEREAKIESLEEKMKSVrdstELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYE 1736
Cdd:pfam02463  778 EEREKTEKLKVEEEKEEKLKAQ----EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1737 SEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKN 1816
Cdd:pfam02463  854 EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKY 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1817 LGMENIMGDFQKKMQEKDAVSHSLEQKVKELE----DNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEE 1892
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEEEEERNKRLllakEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIE 1013

                          890
                   ....*....|..
gi 2024469763 1893 NAEEKAKSGLEL 1904
Cdd:pfam02463 1014 ETCQRLKEFLEL 1025
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2162-2205 7.40e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.30  E-value: 7.40e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 2024469763  2162 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPADQTQKILER 2205
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1465-2084 2.19e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 2.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1465 EELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEEL--KRYHEQKDMEQKEVA 1542
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELngELSAADAAVAKDRSE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1543 WQLQQAEKVAFEKDsrlkEAEEKVLNLENEiGSLKAECEAKEREFDQMKSAILKSKEEELKELEERlNAENSCKLADLKK 1622
Cdd:pfam12128  324 LEALEDQHGAFLDA----DIETAAADQEQL-PSWQSELENLEERLKALTGKHQDVTAKYNRRRSKI-KEQNNRDIAGIKD 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1623 KAEqkigSIKRELVRQMEEKEQQLKQdRENQVRHlEQKVQEREAKIESLE-----EKMKSVRDSTELEREMLQKIESTKA 1697
Cdd:pfam12128  398 KLA----KIREARDRQLAVAEDDLQA-LESELRE-QLEAGKLEFNEEEYRlksrlGELKLRLNQATATPELLLQLENFDE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1698 AVEQEKNEviksvQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEkrhreeQSVTEGL 1777
Cdd:pfam12128  472 RIERAREE-----QEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQA------GTLLHFL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1778 REELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDF----------QKKMQEKDAVSHSLE---QKV 1844
Cdd:pfam12128  541 RKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRidvpewaaseEELRERLDKAEEALQsarEKQ 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1845 KELEDNLAKVN---EVHKTEMEDRSLKYEENLKSLQQ-QLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQA 1920
Cdd:pfam12128  621 AAAEEQLVQANgelEKASREETFARTALKNARLDLRRlFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQA 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1921 KLEEAEREKqklrkdvnslqKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEdielKHSSTLKQLMREFNTQLAQKEM 2000
Cdd:pfam12128  701 WLEEQKEQK-----------REARTEKQAYWQVVEGALDAQLALLKAAIAARRS----GAKAELKALETWYKRDLASLGV 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2001 ELETAVKetisKAQEVESELIENHQIEttQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQ 2080
Cdd:pfam12128  766 DPDVIAK----LKREIRTLERKIERIA--VRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKL 839


                   ....
gi 2024469763 2081 RMAE 2084
Cdd:pfam12128  840 RRAK 843
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2163-2202 3.30e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 42.73  E-value: 3.30e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2024469763 2163 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPADQTQKI 2202
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 134-387 2.31e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.48  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  134 EQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQ----SQDKALRRIGELREELQMDQQAKKHLQEeFDA 209
Cdd:COG3096    839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQanllADETLADRLEELREELDAAQEAQAFIQQ-HGK 917

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  210 SLEEKDQLISVLQT---QVSLLKQRLQngqigielpdpnnQSEPQVQSQTKEINA-ENIVEPGSNEGNEDSVKTL----- 280
Cdd:COG3096    918 ALAQLEPLVAVLQSdpeQFEQLQADYL-------------QAKEQQRRLKQQIFAlSEVVQRRPHFSYEDAVGLLgensd 984

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  281 --ETLNQRVKRQENLLQRCKEMIRSHKERCAQ-------LTNEKEALQEQLEERLQELEKM--------KDLHMGEKTKL 343
Cdd:COG3096    985 lnEKLRARLEQAEEARREAREQLRQAQAQYSQynqvlasLKSSRDAKQQTLQELEQELEELgvqadaeaEERARIRRDEL 1064

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 2024469763  344 ITQLRDAKNLIEQLEQDKGMVIAETKrQMHETLEMKEEEVAQLR 387
Cdd:COG3096   1065 HEELSQNRSRRSQLEKQLTRCEAEMD-SLQKRLRKAERDYKQER 1107
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1048-1192 4.18e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.54  E-value: 4.18e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  1048 EKKLNQQAEELQEKHEmELQEKEQELGDLKEKLatfSAEKEGSRTEITRLK----EEQVKRNETLKQLQEELKQSLAQMS 1123
Cdd:smart00787  146 KEGLDENLEGLKEDYK-LLMKELELLNSIKPKL---RDRKDALEEELRQLKqledELEDCDPTELDRAKEKLKKLLQEIM 221

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763  1124 ALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARItelADKLKTLEEKLQTLQSSH 1192
Cdd:smart00787  222 IKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFT---FKEIEKLKEQLKLLQSLT 287
Abraxas_1 cd23523
BRCA1-A complex subunit Abraxas 1; BRCA1-A complex subunit Abraxas 1, also known as ABRA1, ...
 1911-1984 5.11e-03

BRCA1-A complex subunit Abraxas 1; BRCA1-A complex subunit Abraxas 1, also known as ABRA1, FAM175A, and CCDC98, is involved in DNA damage response and double-strand break (DSB) repair and acts as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex consists of Abraxas 1, BRCC36, BRE, MERIT40, and RAP80, and specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase (DUB) activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX; its DUB is BRCC36, which associates with pseudo-DUB protein Abraxas 1 which lacks the essential Zn2+-coordinating residues required for DUB catalytic function. BRCA1-A opposes homologous recombination (HR) by suppressing resection. It has been shown for BIR (break-induced replication), an HR-subtype that involves extensive DNA resection and mutagenic DNA synthesis; that Abraxas 1 inhibits DNA end resection through regulating the levels of SLX4/MUS81 chromatin loading at DSBs in response to Topoisomerase I (TOP1) inhibitor-induced DNA damage. Familial mutations in the BRCA1-A proteins Abraxas 1 and RAP80 predispose carriers to early-onset breast cancer, analogous to mutations in BRCA1 and BRCA2. BRCA1-A requires the tandem ubiquitin (UIM2)- and SUMO-interacting motifs (SIM) in RAP80 and the BRCC36 DUB to function in DNA repair. BRCA1-A recruits BRCA1 by binding its BRCT domains upon phosphorylation of a motif near the C-terminus of Abraxas 1. BRCA1 binding to BRCA1-A sequesters the HR activator BRCA1 about 2-10 kb distal from DNA break sites, which is posited to limit HR. It is currently unclear how BRCA1-A is functionalized and targeted by RAP80 and Abraxas 1 and how BRCA1 is inhibited when bound to the complex. BRCC36 in BRCA1-A is activated by assembly due to interaction between Glu30 of BRCC36 and Asn170 in Abraxas 1 which structures the activation loop and positions the catalytic Glu33.


Pssm-ID: 467803  Cd Length: 379  Bit Score: 41.43  E-value: 5.11e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763 1911 MQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTlRKEHQQELDIVKKESLEEMEQKIRCEQ-----EDIELKHSSTL 1984
Cdd:cd23523    221 LQEELKKICKKVEESERSVEKLLKDVNRLKEEIAK-RKRAQTQATAEKSVPEEPEENVLLCQAlrtffPNSELLHSCTL 298
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 803-1710 9.29e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 9.29e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  803 SLSQQNTSNEQAKQYEEELAKLQQKLmdLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENtqkam 882
Cdd:TIGR02168  204 SLERQAEKAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----- 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  883 sltqqyeSQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERIStlqgdyenKLKRQENKMEKMKQK 962
Cdd:TIGR02168  277 -------SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE--------ELESKLDELAEELAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  963 SKEMQETFKKKLAEQESKLKkELENKQLEFSQKESEFNAKMLEMAhassAGINDAVSKLESNQKE------QLESLAEAH 1036
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELE-ELEAELEELESRLEELEEQLETLR----SKVAQLELQIASLNNEierleaRLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1037 KRELEEISRSWEKKLNQQAEELQekheMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELK 1116
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQ----AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1117 QSLAQMSALSNSESGLKAQLQKLEGdlsqslkeKSGLQEQISRQKAIEEKDKARIteladkLKTLEEKLQTLQSshskDR 1196
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSG--------LSGILGVLSELISVDEGYEAAI------EAALGGRLQAVVV----EN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1197 ENYEKKIEAFQQQETEVKELVAQLDaywksaeVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKS-- 1274
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELGRVTFLPLD-------SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1275 VQQLQEKDNVIKSMRDDiEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKT 1354
Cdd:TIGR02168  628 VDDLDNALELAKKLRPG-YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1355 INELNVRLEsmvSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVdhctAKLSEWKTKAQTRFTQ 1434
Cdd:TIGR02168  707 LEELEEELE---QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI----EELEERLEEAEEELAE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1435 NHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTaELKIQAARVAELEEHIA 1514
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE-DLEEQIEELSEDIESLA 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1515 QKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAI 1594
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1595 lkskeeelKELEERLNAENSCKLADLKKKAEQKIGSIkRELVRQMEEKEQQLKQ------DRENQVRHLEQKVQEREAKI 1668
Cdd:TIGR02168  939 --------DNLQERLSEEYSLTLEEAEALENKIEDDE-EEARRRLKRLENKIKElgpvnlAAIEEYEELKERYDFLTAQK 1009

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|...
gi 2024469763 1669 ESLEEKMKSVRDS-TELEREMLQKIESTKAAVEQEKNEVIKSV 1710
Cdd:TIGR02168 1010 EDLTEAKETLEEAiEEIDREARERFKDTFDQVNENFQRVFPKL 1052
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1340-2047 5.81e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 5.81e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1340 DLQEKESEISTLNKTINELNVRLESMVS-LTEKEAAISLLSTQHQE--ERLQLINQ-VQELSSSVELLRQEKASALEQVD 1415
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAeLQELEEKLEELRLEVSEleEEIEELQKeLYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1416 HctaklsewktkAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESEL 1495
Cdd:TIGR02168  313 N-----------LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1496 TAelkiQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAF--------EKDSRLKEAEEKVL 1567
Cdd:TIGR02168  382 ET----LRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELkelqaeleELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1568 NLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAEN-SCKLADLKKKAEQKIGSIKR--ELVRQMEEKEQ 1644
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfSEGVKALLKNQSGLSGILGVlsELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1645 QLK---QDRENQVrhLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEViKSVQQTHEEKINKL 1721
Cdd:TIGR02168  538 AIEaalGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGF-LGVAKDLVKFDPKL 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1722 QK-------------DLIEKNKLLQKYESEQR--------------------EGIDSLLELQSKQEELLKKLECAEKRHR 1768
Cdd:TIGR02168  615 RKalsyllggvlvvdDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIA 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1769 EEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELE 1848
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1849 DNLAKVnEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAERE 1928
Cdd:TIGR02168  775 EELAEA-EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1929 KQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIEL----KHSSTLKQLMREFNTQLAQKEMELET 2004
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELreleSKRSELRRELEELREKLAQLELRLEG 933

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 2024469763 2005 A------VKETISKAQEVESELIENHQIETTQLHKKIAEKDDDLKRTVK 2047
Cdd:TIGR02168  934 LevridnLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
PTZ00121 PTZ00121
MAEBL; Provisional
 1420-2022 3.83e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 88.66  E-value: 3.83e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1420 KLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEEL--AQQGKDLDSLKSVLEEKENRIEKQESELTA 1497
Cdd:PTZ00121  1195 KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1498 ELKIQAARVAELEEhiAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQ-AEKVAFEKDSRLKEAEEKVLNLENEIGSL 1576
Cdd:PTZ00121  1275 EEARKADELKKAEE--KKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKkAEEAKKKADAAKKKAEEAKKAAEAAKAEA 1352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1577 KAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQ---KIGSIKRELVRQMEEKEQQLKQDRENQ 1653
Cdd:PTZ00121  1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkkKADELKKAAAAKKKADEAKKKAEEKKK 1432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1654 VRHLEQKVQEREaKIESLEEKMKSVRDSTELEREMLQKI---ESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNK 1730
Cdd:PTZ00121  1433 ADEAKKKAEEAK-KADEAKKKAEEAKKAEEAKKKAEEAKkadEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1731 LLQKYESEQREGIDSLLELQSKQE-ELLKKLEcaEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLAssrEEL 1809
Cdd:PTZ00121  1512 ADEAKKAEEAKKADEAKKAEEAKKaDEAKKAE--EKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA---EEA 1586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1810 KAKEQKNLGMENIMGDFQKKMQEKDAVShslEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKA 1889
Cdd:PTZ00121  1587 KKAEEARIEEVMKLYEEEKKMKAEEAKK---AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA 1663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1890 LEE--NAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAeREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQ 1967
Cdd:PTZ00121  1664 AEEakKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA-KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED 1742

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1968 KIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIE 2022
Cdd:PTZ00121  1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1458-2137 4.09e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 4.09e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1458 EELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDME 1537
Cdd:TIGR02168  186 ENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1538 QKevawQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENscKL 1617
Cdd:TIGR02168  266 EE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE--EL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1618 ADLKKKAEQKigSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRdsTELEReMLQKIESTKA 1697
Cdd:TIGR02168  340 AELEEKLEEL--KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN--NEIER-LEARLERLED 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1698 AVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQS---VT 1774
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQArldSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1775 EGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMG---------DFQKKMQEKDAVSHSLEQKVK 1845
Cdd:TIGR02168  495 ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGgrlqavvveNLNAAKKAIAFLKQNELGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1846 ELEDNLAKVNEVHKTEMEdrSLKYEENLKSLQQQLEERNDRLKALEEN-------------------------------- 1893
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDRE--ILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvvddldnalelakklrpgyrivtldg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1894 ------------AEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVK--K 1959
Cdd:TIGR02168  653 dlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISalR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1960 ESLEEMEQKIRCEQEDIELKHSSTLKQLMREfnTQLAQKEMELETAVKETISKAQEVEsELIENHQIETTQLHKKIAEKD 2039
Cdd:TIGR02168  733 KDLARLEAEVEQLEERIAQLSKELTELEAEI--EELEERLEEAEEELAEAEAEIEELE-AQIEQLKEELKALREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2040 DDLKRTVKKYeEILEAREEEMTTKVHELQTQLEELQKEYKQRMAE----KDHRNSENVTIAELQAQLAQKTTLVNDSKLK 2115
Cdd:TIGR02168  810 AELTLLNEEA-ANLRERLESLERRIAATERRLEDLEEQIEELSEDieslAAEIEELEELIEELESELEALLNERASLEEA 888

                          730       740
                   ....*....|....*....|..
gi 2024469763 2116 EQEFKEQIHVLEDRLKNYEKKM 2137
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKR 910
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1040-1948 4.56e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 4.56e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1040 LEEISRSWeKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSL 1119
Cdd:TIGR02168  195 LNELERQL-KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1120 AQMSALSNsesglkaQLQKLEGDLSQSLKEKSGLQEQISRQKAieekdkaRITELADKLKTLEEKLQTLQSSHSKDRENY 1199
Cdd:TIGR02168  274 LEVSELEE-------EIEELQKELYALANEISRLEQQKQILRE-------RLANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1200 EKKIEAFQQQETEVKELVAQLDAYWKSAEVLlqtksNELIEKCNEKIGIVTCKIADCERQATKVKeAVIIKMNKSVQQLQ 1279
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAELEEL-----ESRLEELEEQLETLRSKVAQLELQIASLN-NEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1280 EKdnvIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKEtcITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELN 1359
Cdd:TIGR02168  414 DR---RERLQQEIEELLKKLEEAELKELQAELEELEEE--LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1360 VRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELlRQEKASALEqvdhctAKLSEwktKAQTRFTQNHETI 1439
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISV-DEGYEAAIE------AALGG---RLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1440 KDLQSKLEVSNTQ-------ATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIqaarVAELEEH 1512
Cdd:TIGR02168  559 KKAIAFLKQNELGrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV----VDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1513 IAQKTSEND-----SLKEELKRYHeqkdmeqKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREF 1587
Cdd:TIGR02168  635 LELAKKLRPgyrivTLDGDLVRPG-------GVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1588 DQMKSAIlkskeeelkeleerlnaensckladlkkkaeqkigsikRELVRQMEEKEQQLKQDREnQVRHLEQKVQEREAK 1667
Cdd:TIGR02168  708 EELEEEL--------------------------------------EQLRKELEELSRQISALRK-DLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1668 IESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEViksvqqthEEKINKLQKDLIEKNKLLQKYESEQREGIDSLL 1747
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL--------EAQIEQLKEELKALREALDELRAELTLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1748 ELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEqakkyslLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQ 1827
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIES-------LAAEIEELEELIEELESELEALLNERASLEEALALLR 893

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1828 KKMQEKDAVSHSLEQKVKELEDNLAKVNEvHKTEMEDRSLKYEENLKSLQQQL-EERNDRLKALEENAEEKAKSGLELQK 1906
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEELRE-KLAQLELRLEGLEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARR 972

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 2024469763 1907 LLGDMQNQQKDL----QAKLEEAEREKQK---LRKDVNSLQKDLRTLRK 1948
Cdd:TIGR02168  973 RLKRLENKIKELgpvnLAAIEEYEELKERydfLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 672-1396 4.88e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 4.88e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  672 EKTLEKLDVKQTELETLSSELSEalkvrqdLEQELSELKSKVGEAKQEFEgKLEAERNQHKEEVEIMlkEHEIsiqdveK 751
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQE-------LEEKLEELRLEVSELEEEIE-ELQKELYALANEISRL--EQQK------Q 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  752 VLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARlMEASLSQQNTSNEQAKQYEEELAKLQQKLMDL 831
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE-LESLEAELEELEAELEELESRLEELEEQLETL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  832 KGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTEREN 911
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  912 DIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFK-KKLAEQESKLKKELENKQL 990
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlSELISVDEGYEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  991 EFSQK--ESEFNAKMLEMAHASSAGINDAV---------SKLESNQKEQLESL--AEAHKRELEEISRSWEKKLN----- 1052
Cdd:TIGR02168  545 GRLQAvvVENLNAAKKAIAFLKQNELGRVTflpldsikgTEIQGNDREILKNIegFLGVAKDLVKFDPKLRKALSyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1053 -------QQAEELQ---------------------------EKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLK 1098
Cdd:TIGR02168  625 vlvvddlDNALELAkklrpgyrivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1099 EEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKL 1178
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1179 KTLEEKLQTLQSSHSKDRENYEKK-------IEAFQQQETEVKELVAQLDAYWKSAEVLLQTksnelIEKCNEKIGIVTC 1251
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREALDELraeltllNEEAANLRERLESLERRIAATERRLEDLEEQ-----IEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1252 KIADCERQATKVKEaviikmnksvqQLQEKDNVIKSMRDDIEGLVTEKEQLQKEgghqkqaATEKETCITQLRKELSENI 1331
Cdd:TIGR02168  860 EIEELEELIEELES-----------ELEALLNERASLEEALALLRSELEELSEE-------LRELESKRSELRRELEELR 921

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1332 NAVTSLREDLQEKESEISTLNKTINELNVRLESMVSltEKEAAISLLSTQHQEERLQLINQVQEL 1396
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAE--ALENKIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 274-1090 4.39e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.19  E-value: 4.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  274 EDSVKTLETLNQRVKRQEnllQRCKEMIRSHKERCAQLTNEKEALQEQLEE--RLQELEKMKDLHMGEKTKLITQLRDAK 351
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEE---AKKTETGKAEEARKAEEAKKKAEDARKAEEarKAEDARKAEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  352 NL--IEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELK-EQKEKFERAA-FEELEKALGMAQRTEE 427
Cdd:PTZ00121  1162 DArkAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKaEEARKAEDAKkAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  428 ARKKLQTEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAelEKLHKEEMATKDQELNERLQAQEREFQ 507
Cdd:PTZ00121  1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA--DEAKKAEEKKKADEAKKKAEEAKKADE 1319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  508 EKMKAALEKNQSECLKTLQEQEQQESL--ALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKR 585
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEaaKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  586 SEELSTLMDS-EKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKlqilqqqhviEIEKMREKQEQEIDTILKEKETVFR 664
Cdd:PTZ00121  1400 AEEDKKKADElKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK----------KADEAKKKAEEAKKAEEAKKKAEEA 1469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  665 THIEEMNEKTLEKLDVKQTEletlssELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEveimlKEHEI 744
Cdd:PTZ00121  1470 KKADEAKKKAEEAKKADEAK------KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA-----KKADE 1538

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  745 SIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSAR----LMEASLSQQNTSNEQAKQYEEE 820
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEArieeVMKLYEEEKKMKAEEAKKAEEA 1618

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  821 LAKLQQ--KLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSD--ENTQKAMSLTQQYESQLKDLQ 896
Cdd:PTZ00121  1619 KIKAEElkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKkaEEAKKAEEDEKKAAEALKKEA 1698

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  897 EEADKAKQTLTERENDIEHVKKVQNEE------MEELKQKLLATEERISTLQGDYENKLKRQENKmekmKQKSKEMQETF 970
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEKKKAEELKKAEeenkikAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLK----KEEEKKAEEIR 1774

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  971 KKKLAEQESKLKKELENKQLEFSQKESEF---NAKMLEMAHASSAGINDAVSKLESNQKE-------QLESLAEAHKREL 1040
Cdd:PTZ00121  1775 KEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnFANIIEGGKEGNLVINDSKEMEDSAIKEvadsknmQLEEADAFEKHKF 1854

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1041 EEISRSWEKKlNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGS 1090
Cdd:PTZ00121  1855 NKNNENGEDG-NKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIP 1903
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 367-1188 4.62e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.11  E-value: 4.62e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  367 ETKRQMHETlemkEEEVAQLRARIKQITTQGEELKEQKEKFER-----AAFEELEKALgMAQRTEEARKKLqtemdEKIK 441
Cdd:TIGR02168  176 ETERKLERT----RENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELAL-LVLRLEELREEL-----EELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  442 AVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRvAELEKLHKEEMATKdqELNERLQAQEREFQEKMKAaLEKNQSEC 521
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLEVSELE-EEIEELQKELYALA--NEISRLEQQKQILRERLAN-LERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  522 LKTLQEQEQQESLALEELELQKKAIQS------ECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMdS 595
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEElkeeleSLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-N 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  596 EKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQhVIEIEKMREKQEQEIDTILKEKETvfrthIEEMNEKTL 675
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAE-LEELEEELEELQEELERLEEALEE-----LREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  676 EKLDVKQTELETLSSELsEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAE------RNQHKEEVEIMLKEH------- 742
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLselisvDEGYEAAIEAALGGRlqavvve 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  743 --EISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELK--ESAQRSEAELVQVSARL---MEASLSQ------QNT 809
Cdd:TIGR02168  554 nlNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLrkaLSYLLGGvlvvddLDN 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  810 SNEQAKQYEEElaklqQKLMDLKGEKLQ----LSEQLVRTECQLNEVKNELElyisqvhELKQQLQEQSDENTQKAMSLt 885
Cdd:TIGR02168  634 ALELAKKLRPG-----YRIVTLDGDLVRpggvITGGSAKTNSSILERRREIE-------ELEEKIEELEEKIAELEKAL- 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  886 QQYESQLKDLQEEADKAKQTLTERENDIehvkkvqnEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKE 965
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQI--------SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  966 MQETFKKKLAEQEsKLKKELENKQLEFSQKESEFNAKMLEmAHASSAGINDAVSKLESNQKEqleslAEAHKRELEEISR 1045
Cdd:TIGR02168  773 AEEELAEAEAEIE-ELEAQIEQLKEELKALREALDELRAE-LTLLNEEAANLRERLESLERR-----IAATERRLEDLEE 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1046 SWEkklnqQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSAL 1125
Cdd:TIGR02168  846 QIE-----ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1126 SNSESGLKAQLQKLEGDLsQSLKEKSGLQEQISRQKAIE--EKDKARITELADKLKTLEEKLQTL 1188
Cdd:TIGR02168  921 REKLAQLELRLEGLEVRI-DNLQERLSEEYSLTLEEAEAleNKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1023-1880 1.50e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.18  E-value: 1.50e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1023 SNQKEQLE-SLAEAHKRELEEISRSWEKKLNQqAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQ 1101
Cdd:TIGR02168  219 KAELRELElALLVLRLEELREELEELQEELKE-AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1102 VKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTL 1181
Cdd:TIGR02168  298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1182 EEKLQTLQS----------SHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEV-LLQTKSNELIEKCNEKIGIVT 1250
Cdd:TIGR02168  378 EEQLETLRSkvaqlelqiaSLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELkELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1251 CKIADCE--RQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEG-------LVTEKEQLQKEGGHQKQAATEKETCIT 1321
Cdd:TIGR02168  458 RLEEALEelREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfsegvkaLLKNQSGLSGILGVLSELISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1322 QLRKELSENINAVTSlrEDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVE 1401
Cdd:TIGR02168  538 AIEAALGGRLQAVVV--ENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1402 LLrqekasaleqvdhctakLSEWktKAQTRFTQNHETIKDLQSKLEVSNTQATKKGeelDKLKEELAQQGKDlDSLKSVL 1481
Cdd:TIGR02168  616 KA-----------------LSYL--LGGVLVVDDLDNALELAKKLRPGYRIVTLDG---DLVRPGGVITGGS-AKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1482 EEKENRIEkqesELTAELKIQAARVAELEEHIAQKTSENDSLKEELkryhEQKDMEQKEVAWQLQQAEKVAFEKDSRLKE 1561
Cdd:TIGR02168  673 LERRREIE----ELEEKIEELEEKIAELEKALAELRKELEELEEEL----EQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1562 AEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEE 1641
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1642 KEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQekneviksvqqtHEEKINKL 1721
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS------------LEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1722 QKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAE-KRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGG 1800
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1801 DLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQL 1880
Cdd:TIGR02168  973 RLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNENFQRVFPKL 1052
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 278-831 5.90e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 5.90e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  278 KTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEkmkdLHMGEKTKLITQLRDAKNLIEQL 357
Cdd:COG1196    239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY----ELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  358 EQDkgmvIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMD 437
Cdd:COG1196    315 EER----LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  438 EKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKN 517
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  518 QSEclktLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRIL--ELESSLAKCSQDDKKRSEELSTLMDS 595
Cdd:COG1196    471 EAA----LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrGLAGAVAVLIGVEAAYEAALEAALAA 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  596 EKKQHNKEVSDIVEKHKEEL-ENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKT 674
Cdd:COG1196    547 ALQNIVVEDDEVAAAAIEYLkAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  675 LEKLDVKQTELetLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLK 754
Cdd:COG1196    627 LVAARLEAALR--RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763  755 EELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQvsARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDL 831
Cdd:COG1196    705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE--EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1439-1966 5.42e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 5.42e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1439 IKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELtAELKIQAARVAELEEHIAQKTS 1518
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE-YELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1519 ENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSK 1598
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1599 EEELKELEERLNAENSCK-LADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAK--IESLEEKM 1675
Cdd:COG1196    393 RAAAELAAQLEELEEAEEaLLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLelLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1676 KSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQ-- 1753
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNiv 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1754 -EELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQE 1832
Cdd:COG1196    553 vEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1833 KDAVSHSLEQKVKELEDNLAkvnevhKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQ 1912
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLE------GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE 706

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024469763 1913 NQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEME 1966
Cdd:COG1196    707 RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 546-1246 5.48e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 5.48e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  546 IQSECDKKLEEMHQEVETFKTRIL--ELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSdiVEKHKEELENVKQQQE 623
Cdd:TIGR02168  207 RQAEKAERYKELKAELRELELALLvlRLEELREELEELQEELKEAEEELEELTAELQELEEK--LEELRLEVSELEEEIE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  624 KLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKetvfrthIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLE 703
Cdd:TIGR02168  285 ELQKELYALANEISRLEQQKQILRERLANLERQLEE-------LEAQLEELESKLDELAEELAELEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  704 QELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQdvekvLKEELNQMKQSLEEKERLLEEAKTREQELKE 783
Cdd:TIGR02168  358 AELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE-----IERLEARLERLEDRRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  784 SAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKN------ELE 857
Cdd:TIGR02168  433 AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfsegvkALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  858 LYISQVHELKQQLQEQ--SDENTQKAMS----------LTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEME 925
Cdd:TIGR02168  513 KNQSGLSGILGVLSELisVDEGYEAAIEaalggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  926 ELK------------------------------------------QKLLATEERISTLQGD--------------YENKL 949
Cdd:TIGR02168  593 ILKniegflgvakdlvkfdpklrkalsyllggvlvvddldnalelAKKLRPGYRIVTLDGDlvrpggvitggsakTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  950 KRQENKMEKMKQKSKEMQETFKKKLAEQEsKLKKELENKQLEFSQKESEFNAKMLEMahaSSAGINDAVSKLESNQKEQL 1029
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALA-ELRKELEELEEELEQLRKELEELSRQI---SALRKDLARLEAEVEQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1030 ESLAEAHKRELEEISRSWEKKLNQQAEELQEkHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLK 1109
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAE-AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1110 QLQ--------------EELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELA 1175
Cdd:TIGR02168  828 SLErriaaterrledleEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024469763 1176 DKLKTLEEKLQTLQSSHSKDRENYEK---KIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKI 1246
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGlevRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 672-1222 6.10e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 6.10e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  672 EKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHK-----EEVEIMLKEHEISI 746
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAelarlEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  747 QDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQ 826
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  827 KLmDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTL 906
Cdd:COG1196    395 AA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  907 TERENDIEhvkkvQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLaeqESKLKKELE 986
Cdd:COG1196    474 LLEAALAE-----LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY---EAALEAALA 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  987 NKQLEFSQKESEFNAKMLEMAHASSAGindAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMEL 1066
Cdd:COG1196    546 AALQNIVVEDDEVAAAAIEYLKAAKAG---RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1067 QEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQS 1146
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024469763 1147 LKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDA 1222
Cdd:COG1196    703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 609-1358 8.25e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.33  E-value: 8.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  609 EKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDvkqTELETL 688
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIE---RQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  689 SSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEiSIQDVEKVLKEELNQMKQSLEEKE 768
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA-SLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  769 RLLEEAKTREQELKESAQRSEAELVQVSARL------MEASLSQ-------QNTSNEQAKQYEEELAKLQQKLMDLKGEK 835
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYaelkeeLEDLRAEleevdkeFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  836 LQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDE---NTQKAMSLTQQ---YESQLKDLQEEADKAKQTLTER 909
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEikkQEWKLEQLAADlskYEQELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  910 ENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYenKLKRQENKMEKMKQKSKEMQETFKKK--------LAEQESKL 981
Cdd:TIGR02169  489 QRELAEAEAQARASEERVRGGRAVEEVLKASIQGVH--GTVAQLGSVGERYATAIEVAAGNRLNnvvveddaVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  982 KKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQ------------LESLAEAhkRELEEISRswek 1049
Cdd:TIGR02169  567 LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEpafkyvfgdtlvVEDIEAA--RRLMGKYR---- 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1050 kLNQQAEELQEKH------EMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMS 1123
Cdd:TIGR02169  641 -MVTLEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1124 ALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSkdRENYEKKI 1203
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS--HSRIPEIQ 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1204 EAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATkvKEAVIIKMNKSVQQLQEKDN 1283
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE--IENLNGKKEELEEELEELEA 875

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1284 VIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSEninavtsLREDLQEKESEISTLNKTINEL 1358
Cdd:TIGR02169  876 ALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSE-------LKAKLEALEEELSEIEDPKGED 943
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1276-2022 9.60e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 9.60e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1276 QQLQEKDNVIKSMRDDIEGLVTEKEQLQK----EGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTL 1351
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRREREKAERyqalLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISEL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1352 NKTINELNVRLEsmvsltEKEAAISLLStqhQEERLQLINQVQELSSSVELLR---QEKASALEQVDHCTAKLSEWKTKA 1428
Cdd:TIGR02169  264 EKRLEEIEQLLE------ELNKKIKDLG---EEEQLRVKEKIGELEAEIASLErsiAEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1429 QTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDL----DSLKSVLEEKE------NRIEKQESELTAE 1498
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrDELKDYREKLEklkreiNELKRELDRLQEE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1499 LKIQAARVAELEEHIAQKTSENDSLKEELkryhEQKDMEQKEVAWQLQQAEKVafekdsrLKEAEEKVLNLENEIGSLKA 1578
Cdd:TIGR02169  415 LQRLSEELADLNAAIAGIEAKINELEEEK----EDKALEIKKQEWKLEQLAAD-------LSKYEQELYDLKEEYDRVEK 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1579 ECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCK-----LADLKKKAEQKIGSIKRELVRQM-----------EEK 1642
Cdd:TIGR02169  484 ELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtVAQLGSVGERYATAIEVAAGNRLnnvvveddavaKEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1643 EQQLKQDRENQVRHL---EQKVQEREAKIESLEEKMKSVRDSTELEremlQKIESTKAAVEQEkNEVIKSVQQTHEEKIN 1719
Cdd:TIGR02169  564 IELLKRRKAGRATFLplnKMRDERRDLSILSEDGVIGFAVDLVEFD----PKYEPAFKYVFGD-TLVVEDIEAARRLMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1720 ----KLQKDLIEKNKLL-------QKYESEQREGIDSLLELQSKQEELLKKLE-CAEKRHREEQSVTEGLRE------EL 1781
Cdd:TIGR02169  639 yrmvTLEGELFEKSGAMtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSsLQSELRRIENRLDELSQElsdasrKI 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1782 EEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLA----KVNEV 1857
Cdd:TIGR02169  719 GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLShsriPEIQA 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1858 HKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVN 1937
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1938 SLQKDLRTLRKEHQQeldivKKESLEEMEQKIRCEQEDIELKhsstlKQLMREFNTQLAQKEMELETAVKETISKAQEVE 2017
Cdd:TIGR02169  879 DLESRLGDLKKERDE-----LEAQLRELERKIEELEAQIEKK-----RKRLSELKAKLEALEEELSEIEDPKGEDEEIPE 948


                   ....*
gi 2024469763 2018 SELIE 2022
Cdd:TIGR02169  949 EELSL 953
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 609-1189 1.21e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 1.21e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  609 EKHKEELENVKQQQEKLWTEKLQILQQQHVIE--IEKMREKQEQEIDTILKEKETVFRTHIEEmnEKTLEKLDVKQTELE 686
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEaeLEELRLELEELELELEEAQAEEYELLAEL--ARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  687 TLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEgkLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEE 766
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELE--EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  767 KERLLEEAKTREQELKESAQRSEAELvqvsarlmEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTE 846
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERL--------ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  847 CQLNEVKNELELYISQVHELKQQLQE-QSDENTQKAMSLTQQYESQ---LKDLQEEADKAKQTLTERENDIEHVKKVQNE 922
Cdd:COG1196    463 ELLAELLEEAALLEAALAELLEELAEaAARLLLLLEAEADYEGFLEgvkAALLLAGLRGLAGAVAVLIGVEAAYEAALEA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  923 EMEELKQKLLATEERISTLQGDYEnKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAK 1002
Cdd:COG1196    543 ALAAALQNIVVEDDEVAAAAIEYL-KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1003 MLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLAT 1082
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1083 FSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISR--- 1159
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgp 781

                          570       580       590
                   ....*....|....*....|....*....|....
gi 2024469763 1160 --QKAIEEKD--KARITELADKLKTLEEKLQTLQ 1189
Cdd:COG1196    782 vnLLAIEEYEelEERYDFLSEQREDLEEARETLE 815
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 278-976 1.59e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 1.59e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  278 KTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLhMGEKTKLITQLRDAKNLIEQL 357
Cdd:TIGR02168  281 EEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE-LAELEEKLEELKEELESLEAE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  358 EQDKGMVIAETKRQMH---ETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQT 434
Cdd:TIGR02168  360 LEELEAELEELESRLEeleEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQ 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  435 EMDEKIKAVEKANEEERVNLQQELTRVKQEVVEImkkssedRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAAL 514
Cdd:TIGR02168  440 AELEELEEELEELQEELERLEEALEELREELEEA-------EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALL 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  515 EKNQ--SECLKTLQEQ-EQQESLALEELELQKKAIQSECDKKLEEMHQEVETFK----TRILELESSLAKCSQDDKKRSE 587
Cdd:TIGR02168  513 KNQSglSGILGVLSELiSVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKqnelGRVTFLPLDSIKGTEIQGNDRE 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  588 ELSTL---------MDSEKKQHNKEVSDIVEKHK--EELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTIL 656
Cdd:TIGR02168  593 ILKNIegflgvakdLVKFDPKLRKALSYLLGGVLvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSI 672

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  657 KEKETVFRTHIEEMnEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEgKLEAERNQHKEEVE 736
Cdd:TIGR02168  673 LERRREIEELEEKI-EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA-RLEAEVEQLEERIA 750

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  737 IMLKEHEiSIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQaKQ 816
Cdd:TIGR02168  751 QLSKELT-ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL-ES 828

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  817 YEEELAKLQQKLMDLKGEKLQLSEQLVRtecqLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQ 896
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIES----LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  897 EEADKAKQTLTERENDIEHVKKVQNeEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAE 976
Cdd:TIGR02168  905 ELESKRSELRRELEELREKLAQLEL-RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1458-2020 2.42e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 2.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1458 EELDKLK-EELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELkrYHEQKDM 1536
Cdd:COG1196    220 EELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE--YELLAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1537 EQKEVAWQLQQAekvafekdsRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENscK 1616
Cdd:COG1196    298 ARLEQDIARLEE---------RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE--A 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1617 LADLKKKAEQKIGSIKRELVRQMEEKEQQLKQdrENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTK 1696
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAEL--AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1697 AAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEG 1776
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1777 LREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQ----KKMQEKDAVSHSLEQKVKELEDNLA 1852
Cdd:COG1196    525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflplDKIRARAALAAALARGAIGAAVDLV 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1853 KVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKL 1932
Cdd:COG1196    605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1933 RKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHsstLKQLMREFNTQLAQKEMELETAVKETISK 2012
Cdd:COG1196    685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA---EREELLEELLEEEELLEEEALEELPEPPD 761


                   ....*...
gi 2024469763 2013 AQEVESEL 2020
Cdd:COG1196    762 LEELEREL 769
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 872-1741 2.78e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 2.78e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  872 EQSDENTQKAMSLTQQYESQLKDLQEEADKAkqtltERENDIEhvKKVQNEEMEELKQKLLATEERISTLQGDYENKLKR 951
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKA-----ERYQALL--KEKREYEGYELLKEKEALERQKEAIERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  952 QENKMEKMKQKSKEMQETfKKKLAEQESKLKKELENKQLEFSQKESEFNAKmLEMAHASSAGINDAVSKLEsNQKEQLES 1031
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEI-EQLLEELNKKIKDLGEEEQLRVKEKIGELEAE-IASLERSIAEKERELEDAE-ERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1032 LAEAHKRELEEISR---SWEKKLNQQAEELQEKHEmELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETL 1108
Cdd:TIGR02169  330 EIDKLLAEIEELEReieEERKRRDKLTEEYAELKE-ELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1109 KQLQEELKQSLAQMSALSNSESGLKAQLQKLEgdlsqslkeksglqeqisrqkaieekdkARITELADKLKTLEEKLQTL 1188
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELE----------------------------EEKEDKALEIKKQEWKLEQL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1189 QSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQT----KSNELIEKCNEK--IGIVTCKIADCERQATK 1262
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERvrggRAVEEVLKASIQgvHGTVAQLGSVGERYATA 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1263 VKEAVIIKMNKSVqqlQEKDNVIKSMrddIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAV-------- 1334
Cdd:TIGR02169  541 IEVAAGNRLNNVV---VEDDAVAKEA---IELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVefdpkyep 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1335 --------TSLREDLQE-KESEISTLNKTIN-ELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLR 1404
Cdd:TIGR02169  615 afkyvfgdTLVVEDIEAaRRLMGKYRMVTLEgELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1405 QEKASALEQVDHCTAKLSEwktkaqtrftqNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEK 1484
Cdd:TIGR02169  695 SELRRIENRLDELSQELSD-----------ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1485 ENRIEKQESELTA-ELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQK---DMEQKEVAWQLQQAEKVAFEKDSRLK 1560
Cdd:TIGR02169  764 EARIEELEEDLHKlEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLreiEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1561 EAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENscKLADLKKKAEQKIGSIKRELVRQME 1640
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA--QLRELERKIEELEAQIEKKRKRLSE 921

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1641 EKEQqlKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMlQKIESTKAAVEQEKNEVIKSvQQTHEEKINK 1720
Cdd:TIGR02169  922 LKAK--LEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEI-RALEPVNMLAIQEYEEVLKR-LDELKEKRAK 997

                          890       900
                   ....*....|....*....|.
gi 2024469763 1721 LQKDLIEKNKLLQKYESEQRE 1741
Cdd:TIGR02169  998 LEEERKAILERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1027-1797 4.07e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 4.07e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1027 EQLESLAEAHKRELEEISRSWEKKLNQQAEeLQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNE 1106
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERYQAL-LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1107 TLKQLQEELKQSLAQMSALSNSES--------GLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKL 1178
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLGEEEQlrvkekigELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1179 KTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVL---------LQTKSNELIEKCNEKIGIV 1249
Cdd:TIGR02169  346 EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLkreinelkrELDRLQEELQRLSEELADL 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1250 TCKIADCERQATKV---KEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKE 1326
Cdd:TIGR02169  426 NAAIAGIEAKINELeeeKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1327 LSENINAVTSLREDLQEKESEISTLNKTINE--------LNVRLESMVSLTEKEA--AISLLStQHQEERLQLI--NQVQ 1394
Cdd:TIGR02169  506 VRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaAGNRLNNVVVEDDAVAkeAIELLK-RRKAGRATFLplNKMR 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1395 ELSSSVELLRQEKA--SALEQVDhCTAKLSE--WKTKAQTRFTQNHETIKDLQSKLEVsntqATKKGEELDK-------- 1462
Cdd:TIGR02169  585 DERRDLSILSEDGVigFAVDLVE-FDPKYEPafKYVFGDTLVVEDIEAARRLMGKYRM----VTLEGELFEKsgamtggs 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1463 ------------LKEELAQQGKDLDSLK---SVLEEKENRIEKQESELTAELKIQAARVAELEEHIaqktsendslkEEL 1527
Cdd:TIGR02169  660 raprggilfsrsEPAELQRLRERLEGLKrelSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-----------EQL 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1528 KRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEE 1607
Cdd:TIGR02169  729 EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVS 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1608 RLNAENSCKLADLKKK--AEQKIGSIKRELVRQMEEKEQQlKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELE 1685
Cdd:TIGR02169  809 RIEARLREIEQKLNRLtlEKEYLEKEIQELQEQRIDLKEQ-IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDL 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1686 REMLQKIESTKAAVEQEKNEvIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSkQEELLKKLECAEK 1765
Cdd:TIGR02169  888 KKERDELEAQLRELERKIEE-LEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-LEDVQAELQRVEE 965

                          810       820       830
                   ....*....|....*....|....*....|..
gi 2024469763 1766 RHREEQSVTEGLREELEEQAKKYSLLVDEHAR 1797
Cdd:TIGR02169  966 EIRALEPVNMLAIQEYEEVLKRLDELKEKRAK 997
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 367-998 4.73e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 4.73e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  367 ETKRQMHETlemkEEEVAQLRARIKQITTQGEELKEQKEKFERAafeelekalgmaqrteearKKLQTEMDEKiKAVEKA 446
Cdd:COG1196    176 EAERKLEAT----EENLERLEDILGELERQLEPLERQAEKAERY-------------------RELKEELKEL-EAELLL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  447 NEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSECLKTLQ 526
Cdd:COG1196    232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  527 EQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAkcsqDDKKRSEELSTLMDSEKKQHNKEVSD 606
Cdd:COG1196    312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA----EAEEALLEAEAELAEAEEELEELAEE 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  607 IVEKHKEELENVKQQQEklwtekLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEmnEKTLEKLDVKQTELE 686
Cdd:COG1196    388 LLEALRAAAELAAQLEE------LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL--EEAAEEEAELEEEEE 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  687 TLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELnqmkqsLEE 766
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI------GVE 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  767 KERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTE 846
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  847 CQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAK-QTLTERENDIEHVKKVQNEEME 925
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELlAALLEAEAELEELAERLAEEEL 693

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024469763  926 ELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESE 998
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1049-1579 4.85e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 4.85e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1049 KKLNQQAE------ELQ-EKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQ 1121
Cdd:COG1196    203 EPLERQAEkaeryrELKeELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1122 MSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEK 1201
Cdd:COG1196    283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1202 KIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEkcnekigivtckiadcERQATKVKEAVIIKMNKSVQQLQEK 1281
Cdd:COG1196    363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ----------------LEELEEAEEALLERLERLEEELEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1282 DNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVR 1361
Cdd:COG1196    427 EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1362 LESMVSLTEK-------------------------------------------EAAISLLSTQHQ----EERLQLINQVQ 1394
Cdd:COG1196    507 LEGVKAALLLaglrglagavavligveaayeaaleaalaaalqnivveddevaAAAIEYLKAAKAgratFLPLDKIRARA 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1395 ELSSSVELLRQEKASALEQVD----HCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQ 1470
Cdd:COG1196    587 ALAAALARGAIGAAVDLVASDlreaDARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1471 GKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEK 1550
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                          570       580
                   ....*....|....*....|....*....
gi 2024469763 1551 VAFEKDSRLKEAEEKVLNLENEIGSLKAE 1579
Cdd:COG1196    747 LLEEEALEELPEPPDLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 812-1347 6.98e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 6.98e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  812 EQAKQYEEELAKLQQKLMDLKGEKLQlsEQLVRTECQLNEVKNELELYISQVHELKQQLQE--QSDENTQKAMSLTQQYE 889
Cdd:COG1196    213 ERYRELKEELKELEAELLLLKLRELE--AELEELEAELEELEAELEELEAELAELEAELEElrLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  890 SQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQET 969
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  970 FKKKLAEQESklKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEK 1049
Cdd:COG1196    371 EAELAEAEEE--LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1050 KLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQM--SALSN 1127
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlaGAVAV 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1128 SESGLKAQLQKLEGDLSQSLKEKSGLQEQiSRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQ 1207
Cdd:COG1196    529 LIGVEAAYEAALEAALAAALQNIVVEDDE-VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1208 QQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKS 1287
Cdd:COG1196    608 LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1288 MRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESE 1347
Cdd:COG1196    688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 130-971 2.00e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.70  E-value: 2.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  130 SLSKEQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQSQDkALRRIGELREELQMDQQAKKHLQEEFDA 209
Cdd:TIGR02168  224 ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL-EVSELEEEIEELQKELYALANEISRLEQ 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  210 SLEE-KDQLISVLQTQVSLLKQRLQNGQIGIELPDPNNQSEPQVQSQTKEINAENIVEPGSNEGNEDSVKTLETLNQRVK 288
Cdd:TIGR02168  303 QKQIlRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  289 RQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKM-KDLHMGEKTKLITQLRDAKNLIEQLEQDKGMVIAE 367
Cdd:TIGR02168  383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  368 TK------RQMHETLEMKEEEVAQLRARIKQIttqgEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMDEKiK 441
Cdd:TIGR02168  463 LEelreelEEAEQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE-A 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  442 AVEKANEEervNLQQELTRVKQEV---VEIMKKSSEDRVAELEkLHKEEMATKDQELNERLQAQE---------REFQEK 509
Cdd:TIGR02168  538 AIEAALGG---RLQAVVVENLNAAkkaIAFLKQNELGRVTFLP-LDSIKGTEIQGNDREILKNIEgflgvakdlVKFDPK 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  510 MKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEEL 589
Cdd:TIGR02168  614 LRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  590 stlmdsekkqhnKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQeidtilkEKETVFRTHIEE 669
Cdd:TIGR02168  694 ------------AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV-------EQLEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  670 MNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEgKLEAErnqhkeeveimLKEHEISIQDV 749
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD-ELRAE-----------LTLLNEEAANL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  750 EKVLKEELNQMKQSLEEKERLLEEAKTREQELK--ESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQK 827
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIEslAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  828 LMDLKGEKLQLSEQLVRTECQLNEVKNELElyisqvhELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLT 907
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLE-------GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024469763  908 ERENDIEHVKKVQNEEMEELKQKllatEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFK 971
Cdd:TIGR02168  976 RLENKIKELGPVNLAAIEEYEEL----KERYDFLTAQKEDLTEAKETLEEAIEEIDREARERFK 1035
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 317-872 2.63e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.20  E-value: 2.63e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  317 ALQEQLEERLQELEKMKDLHM-GEKTKLITQLRDAKNLIEQLEqdkgmviaetkrqmhETLEMKEEEVAQLRARIKQITT 395
Cdd:COG1196    217 ELKEELKELEAELLLLKLRELeAELEELEAELEELEAELEELE---------------AELAELEAELEELRLELEELEL 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  396 QGEELKEQkekfERAAFEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKAnEEERVNLQQELTRVKQEVVEIMKK--SS 473
Cdd:COG1196    282 ELEEAQAE----EYELLAELARLEQDIARLEERRRELEERLEELEEELAEL-EEELEELEEELEELEEELEEAEEEleEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  474 EDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKK 553
Cdd:COG1196    357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  554 LEEMHQEVETFKTRILELES---SLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSdiVEKHKEELENVKQQQEKLWTEKL 630
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEeeeALLELLAELLEEAALLEAALAELLEELAEAAA--RLLLLLEAEADYEGFLEGVKAAL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  631 QILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEK---------------LDVKQTELETLSSELSEA 695
Cdd:COG1196    515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaieylkaakagratfLPLDKIRARAALAAALAR 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  696 LKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAK 775
Cdd:COG1196    595 GAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  776 TREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNE 855
Cdd:COG1196    675 LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754

                          570
                   ....*....|....*..
gi 2024469763  856 LELYISQVHELKQQLQE 872
Cdd:COG1196    755 ELPEPPDLEELERELER 771
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 399-1186 6.72e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.07  E-value: 6.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  399 ELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVA 478
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  479 ELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSEC---LKTLQEQEQQESLALEELELQKKAIQSECDKKLE 555
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLakeEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  556 EMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNkevsdIVEKHKEELENVKQQQEKLWTEKLQILQQ 635
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEE-----LLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  636 QHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGE 715
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  716 AKQE--FEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELV 793
Cdd:pfam02463  484 EQLEllLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  794 QVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEqlvRTECQLNEVKNELELYISQVHELKQQLQEQ 873
Cdd:pfam02463  564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK---ATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  874 SDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQE 953
Cdd:pfam02463  641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  954 NKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLA 1033
Cdd:pfam02463  721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1034 EAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQE 1113
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024469763 1114 ELKQSLAQMSALSNSESGLKAQLQKLEGDLSQsLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQ 1186
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLL-EEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEE 952
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 812-1586 9.02e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.79  E-value: 9.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  812 EQAKQYEEELAKLQQ-KLMDLKGEKLQLSEQLVRTECQLNEVKNELElyisqvhELKQQLQEQSDENTQKAMSLTQQYES 890
Cdd:TIGR02169  208 EKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELE-------KLTEEISELEKRLEEIEQLLEELNKK 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  891 QLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQkllaTEERISTLQGDYENKLKRQENKMEKMKQKSKEmqetf 970
Cdd:TIGR02169  281 IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELED----AEERLAKLEAEIDKLLAEIEELEREIEEERKR----- 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  971 KKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAgINDAVSKLESNQKEQLESLAEAHKRELEEisrsweKK 1050
Cdd:TIGR02169  352 RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK-LEKLKREINELKRELDRLQEELQRLSEEL------AD 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1051 LNQQAEELQEKH---EMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSN 1127
Cdd:TIGR02169  425 LNAAIAGIEAKInelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1128 SESG-------LKAQLQKLEGDLSQSLKEKSGLQEQI-----SRQKAIEEKDKARITELADKLKTLE---------EKLQ 1186
Cdd:TIGR02169  505 RVRGgraveevLKASIQGVHGTVAQLGSVGERYATAIevaagNRLNNVVVEDDAVAKEAIELLKRRKagratflplNKMR 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1187 TLQSSHSKDREN-----------YEKKIEAFQQQETEVKELVAQLDAYWK-SAEVLLQTKSNELIEKCN----------- 1243
Cdd:TIGR02169  585 DERRDLSILSEDgvigfavdlveFDPKYEPAFKYVFGDTLVVEDIEAARRlMGKYRMVTLEGELFEKSGamtggsraprg 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1244 ---------EKIGIVTCKIADCERQatkvKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAAT 1314
Cdd:TIGR02169  665 gilfsrsepAELQRLRERLEGLKRE----LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1315 EKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLeSMVSLTEKEAAISLLSTQHQEERLQLINQVQ 1394
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL-SHSRIPEIQAELSKLEEEVSRIEARLREIEQ 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1395 ELSSS---VELLRQEKASALEQVDHCTAKLSEwktkaqtrftqNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQG 1471
Cdd:TIGR02169  820 KLNRLtleKEYLEKEIQELQEQRIDLKEQIKS-----------IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1472 KDLDSLKSVLEEKENRIEKQE----------SELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEV 1541
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEaqiekkrkrlSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIR 968

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024469763 1542 AWQ------LQQAEKVAfekdSRLKEAEEKVLNLENEIGSLK---AECEAKERE 1586
Cdd:TIGR02169  969 ALEpvnmlaIQEYEEVL----KRLDELKEKRAKLEEERKAILeriEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 122-961 9.33e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 9.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  122 EEVSGNADSLSK-EQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQSQDKALRRIGELREELQMDQQAK 200
Cdd:TIGR02169  160 DEIAGVAEFDRKkEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  201 KHLQEEFDASLEEKDQLISVLQTQVSLLKQRLQN-GQIGIELPDPNNQSEPQVQSQTKEINAENIVEPGSNEGNEDSVKT 279
Cdd:TIGR02169  240 EAIERQLASLEEELEKLTEEISELEKRLEEIEQLlEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  280 LEtlnQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQ 359
Cdd:TIGR02169  320 AE---ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  360 --DKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEkferAAFEELEKALGMAQRTEEARKKLQTEMd 437
Cdd:TIGR02169  397 lkREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKE----DKALEIKKQEWKLEQLAADLSKYEQEL- 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  438 EKIKAVEKANEEERVNLQQELTRVKQEV------------VEIMKKSSED----RVAELEKLHKEEMATKDQELNERLQA 501
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQAraseervrggraVEEVLKASIQgvhgTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  502 QEREFQEKMKAALEKNQSECLKT---LQEQEQQESLALEELELQKKAIQS-----ECDKK-----------------LEE 556
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLKRRKAGRatfLPLNKMRDERRDLSILSEDGVIGFavdlvEFDPKyepafkyvfgdtlvvedIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  557 MHQEVETFKTRILE---LESSLAKCSQDDKKRSEELSTLMDSEKKQhnkEVSDIVEKHKEELENVKQQQEKLwtEKLQIL 633
Cdd:TIGR02169  632 ARRLMGKYRMVTLEgelFEKSGAMTGGSRAPRGGILFSRSEPAELQ---RLRERLEGLKRELSSLQSELRRI--ENRLDE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  634 QQQHVIEIEKMREKQEQEIDTILKEKETVfrthiEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKV 713
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKL-----KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  714 GEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEElnQMKQSLEEKERLLEEAKTREQELKESAQRSEAELV 793
Cdd:TIGR02169  782 NDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRL--TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  794 QVSARLMEaslsqqntsnEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQ 873
Cdd:TIGR02169  860 NGKKEELE----------EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEAL 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  874 SDENTQKAMSLTQQYESQLKDLQEEADKAK-QTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQ 952
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERI 1009


                   ....*....
gi 2024469763  953 ENKMEKMKQ 961
Cdd:TIGR02169 1010 EEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1456-2135 1.55e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1456 KGEELDKLKEELAQ-QGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQK 1534
Cdd:TIGR02169  209 KAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1535 DMEQK----EVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMK------SAILKSKEEELKE 1604
Cdd:TIGR02169  289 QLRVKekigELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERkrrdklTEEYAELKEELED 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1605 LEERL------NAENSCKLADLKKKAEQ---KIGSIKRELVRQMEEKEQqlkqdRENQVRHLEQKVQEREAKIESLEEKM 1675
Cdd:TIGR02169  369 LRAELeevdkeFAETRDELKDYREKLEKlkrEINELKRELDRLQEELQR-----LSEELADLNAAIAGIEAKINELEEEK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1676 KSVRDSTELEREMLQKIESTKAAVEQEKnEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEE 1755
Cdd:TIGR02169  444 EDKALEIKKQEWKLEQLAADLSKYEQEL-YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQG 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1756 ---LLKKLECAEKRHREEQSVTEGLR------EELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMG-- 1824
Cdd:TIGR02169  523 vhgTVAQLGSVGERYATAIEVAAGNRlnnvvvEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGfa 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1825 ----DFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEME--------------DRSLKYEENLKSLQQQLEERNDR 1886
Cdd:TIGR02169  603 vdlvEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEgelfeksgamtggsRAPRGGILFSRSEPAELQRLRER 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1887 LKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKD---VNSLQKDLRTLRKEHQQELDIVKKEsLE 1963
Cdd:TIGR02169  683 LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEeekLKERLEELEEDLSSLEQEIENVKSE-LK 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1964 EMEQKIRCEQEDI---ELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIENHQiETTQLHKKIAEKDD 2040
Cdd:TIGR02169  762 ELEARIEELEEDLhklEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL-EKEYLEKEIQELQE 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2041 DL------KRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSEnvtIAELQAQLAQKTTLVNDSKL 2114
Cdd:TIGR02169  841 QRidlkeqIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ---LRELERKIEELEAQIEKKRK 917

                          730       740
                   ....*....|....*....|.
gi 2024469763 2115 KEQEFKEQIHVLEDRLKNYEK 2135
Cdd:TIGR02169  918 RLSELKAKLEALEEELSEIED 938
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1523-2137 3.09e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 3.09e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1523 LKEELKRYheqkdmEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEEL 1602
Cdd:COG1196    218 LKEELKEL------EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1603 KELEERLNAENSCKLADLKKKAEQKIgsiKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDST 1682
Cdd:COG1196    292 ELLAELARLEQDIARLEERRRELEER---LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1683 ELEREMLQKIESTKAAVEQEKNEviKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLEC 1762
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEA--LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1763 AEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQknlgmenimgdfQKKMQEKDAVSHSLEQ 1842
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE------------AEADYEGFLEGVKAAL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1843 KVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLgdmqnqqKDLQAKL 1922
Cdd:COG1196    515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD-------KIRARAA 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1923 EEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEmeqkircEQEDIELKHSSTLKQLMREfntqlAQKEMEL 2002
Cdd:COG1196    588 LAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRAVTLAGRLRE-----VTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2003 ETAVKETISKAQEVESELIENHQIETTQLHKKIAEKDDDLKRTVKKyeeileareeemttKVHELQTQLEELQKEYKQRM 2082
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA--------------EEEEERELAEAEEERLEEEL 721

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 2083 AEKDHRNSENVTIAELQAQLAQKTTLVNDSKLKEQEFKEQIHVLEDRLKNYEKKM 2137
Cdd:COG1196    722 EEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
PTZ00121 PTZ00121
MAEBL; Provisional
 734-1470 7.44e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.78  E-value: 7.44e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  734 EVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQvsaRLMEASLSQQNTSNEQ 813
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR---KAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  814 AKQYEE-ELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQL 892
Cdd:PTZ00121  1157 ARKAEDaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAK 1236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  893 KDlQEEADKAkqtltERENDIEHVKKVQNEEMEELKQKLL---ATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQET 969
Cdd:PTZ00121  1237 KD-AEEAKKA-----EEERNNEEIRKFEEARMAHFARRQAaikAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  970 FKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEK 1049
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1050 KLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSE 1129
Cdd:PTZ00121  1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1130 SGLKAQLQKLEGDLSQSLKEKSglqeQISRQKAIEEKDKARITELADKLKTLEEKlqtLQSSHSKDRENYEKKIEAFQQQ 1209
Cdd:PTZ00121  1471 KADEAKKKAEEAKKADEAKKKA----EEAKKKADEAKKAAEAKKKADEAKKAEEA---KKADEAKKAEEAKKADEAKKAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1210 ETEVKELVAQLDAYWKSAEVllqtKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMR 1289
Cdd:PTZ00121  1544 EKKKADELKKAEELKKAEEK----KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1290 DDIEGLVTEKEQLQKEGGHQKQAATEKETCiTQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLT 1369
Cdd:PTZ00121  1620 IKAEELKKAEEEKKKVEQLKKKEAEEKKKA-EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1370 EKEAAISLLSTQHQEERlqlinqvqelsSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVS 1449
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEK-----------KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767

                          730       740
                   ....*....|....*....|.
gi 2024469763 1450 NTQATKKGEELDKLKEELAQQ 1470
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEELDEE 1788
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 161-712 1.04e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 1.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  161 YQVIQREKKKLQGILS-----------QSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSLLK 229
Cdd:COG1196    215 YRELKEELKELEAELLllklreleaelEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  230 QRLQNGQIGIelpDPNNQSEPQVQSQTKEINAENIVEpgsNEGNEDSVKTLETLNQRVKRQENLLQRCKEMIRSHKERCA 309
Cdd:COG1196    295 AELARLEQDI---ARLEERRRELEERLEELEEELAEL---EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  310 QLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRAR 389
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  390 IKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMDEKIKAVE--KANEEERVNLQQELTRVKQEVVE 467
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYegFLEGVKAALLLAGLRGLAGAVAV 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  468 IMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAA--LEKNQSECLKTLQEQEQQESLALEELELQKKA 545
Cdd:COG1196    529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtfLPLDKIRARAALAAALARGAIGAAVDLVASDL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  546 IQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKL 625
Cdd:COG1196    609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  626 WTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQE 705
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768


                   ....*..
gi 2024469763  706 LSELKSK 712
Cdd:COG1196    769 LERLERE 775
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1017-1904 1.17e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.84  E-value: 1.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1017 AVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITR 1096
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1097 LKEEQVKRNETLKQLQEELKQslAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELAD 1176
Cdd:pfam02463  243 QELLRDEQEEIESSKQEIEKE--EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1177 KLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDaywksaEVLLQTKSNELIEKCNEKIGIVTCKIADC 1256
Cdd:pfam02463  321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQ------EKLEQLEEELLAKKKLESERLSSAAKLKE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1257 ERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTS 1336
Cdd:pfam02463  395 EELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1337 LREDLQEKESEISTLNKTINElnvRLESMVSLTEKEAAISLLSTQHQEERLQLInqvqelSSSVELLRQEKASALEQVDH 1416
Cdd:pfam02463  475 KETQLVKLQEQLELLLSRQKL---EERSQKESKARSGLKVLLALIKDGVGGRII------SAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1417 CTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVsntqATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELT 1496
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGA----RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1497 AELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSL 1576
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1577 KAECEAKEREFDQMKSAILKSKEEELKELEERLNAEnsckLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRH 1656
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEELLADRVQEAQDKINEE----LKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1657 LEQKVQEREAKIESLEEKMKSVrdstELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYE 1736
Cdd:pfam02463  778 EEREKTEKLKVEEEKEEKLKAQ----EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1737 SEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKN 1816
Cdd:pfam02463  854 EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKY 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1817 LGMENIMGDFQKKMQEKDAVSHSLEQKVKELE----DNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEE 1892
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEEEEERNKRLllakEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIE 1013

                          890
                   ....*....|..
gi 2024469763 1893 NAEEKAKSGLEL 1904
Cdd:pfam02463 1014 ETCQRLKEFLEL 1025
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 922-1759 1.53e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 1.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  922 EEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNa 1001
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ- 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1002 kmLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLA 1081
Cdd:pfam02463  259 --EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1082 TFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSEsGLKAQLQKLEGDLSQSLKEKSGLQEQISRQK 1161
Cdd:pfam02463  337 IEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESE-RLSSAAKLKEEELELKSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1162 AIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEK 1241
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1242 cnEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKegghqKQAATEKETCIT 1321
Cdd:pfam02463  496 --EERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSAT-----ADEVEERQKLVR 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1322 QLRKELSENINAVTsLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVE 1401
Cdd:pfam02463  569 ALTELPLGARKLRL-LIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1402 LLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVL 1481
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1482 EEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKE 1561
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1562 AEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEE 1641
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1642 KEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKL 1721
Cdd:pfam02463  888 LESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL 967

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 2024469763 1722 QKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKK 1759
Cdd:pfam02463  968 AKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKK 1005
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 522-1240 1.59e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 1.59e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  522 LKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCS---QDDKKRSEELSTLMDSEKK 598
Cdd:TIGR02169  200 LERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTeeiSELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  599 QHNKEVSDIVEKHKEELENVKQQQEKLwtEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETvFRTHIEEmnektlekl 678
Cdd:TIGR02169  280 KIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEE-LEREIEE--------- 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  679 dvKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEgKLEAERNQHKEEVEiMLKEHEISIQDVEKVLKEELN 758
Cdd:TIGR02169  348 --ERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK-DYREKLEKLKREIN-ELKRELDRLQEELQRLSEELA 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  759 QMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKqYEEELAKLQQKLMDLKGEKlql 838
Cdd:TIGR02169  424 DLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDR-VEKELSKLQRELAEAEAQA--- 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  839 sEQLVRTECQLNEVKNELELYISQVHELKQQLQeQSDENTQKAM--SLTQQYESQLKDLQEEADKAKQTLTERE------ 910
Cdd:TIGR02169  500 -RASEERVRGGRAVEEVLKASIQGVHGTVAQLG-SVGERYATAIevAAGNRLNNVVVEDDAVAKEAIELLKRRKagratf 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  911 --------------------------NDIEHVKKVQN------------EEMEELKQklLATEERISTLQGDYENK---- 948
Cdd:TIGR02169  578 lplnkmrderrdlsilsedgvigfavDLVEFDPKYEPafkyvfgdtlvvEDIEAARR--LMGKYRMVTLEGELFEKsgam 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  949 ----LKRQENKMEKMKQKSKEMQetfkkkLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASsagindAVSKLESN 1024
Cdd:TIGR02169  656 tggsRAPRGGILFSRSEPAELQR------LRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS------RKIGEIEK 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1025 QKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEME--LQEKEQELGDLKEKLATFSAEKEGSR-TEITRLKEEQ 1101
Cdd:TIGR02169  724 EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEarIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1102 VKRNETLKQLQEELKQSLaqmsalsNSESGLKAQLQKLEGDLSQSLKEksgLQEQISRQKAIEEKDKARITELADKLKTL 1181
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKL-------NRLTLEKEYLEKEIQELQEQRID---LKEQIKSIEKEIENLNGKKEELEEELEEL 873

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024469763 1182 EEKLQTLQSSH---SKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIE 1240
Cdd:TIGR02169  874 EAALRDLESRLgdlKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 751-1120 1.73e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 1.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  751 KVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNtsnEQAKQYEEELAKLQQKLMD 830
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR---LELEELELELEEAQAEEYE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  831 LKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQyESQLKDLQEEADKAKQTLTERE 910
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAEAEEALLEAE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  911 NDIEHvkkvQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQEtfkkkLAEQESKLKKELENKQL 990
Cdd:COG1196    372 AELAE----AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE-----LEEALAELEEEEEEEEE 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  991 EFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKE 1070
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1071 QELGDLkEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLA 1120
Cdd:COG1196    523 AGAVAV-LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKA 571
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 848-1582 2.05e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 2.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  848 QLNEVKNELELYISQVHELKQQLQEQSDENTQKamsltqqyeSQLKDLQEEADKAKQTLTERENDIEHVKKVQNE-EMEE 926
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKA---------ERYQALLKEKREYEGYELLKEKEALERQKEAIErQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  927 LKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKkelenkQLEFSQKESEFNAKMLEM 1006
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA------SLERSIAEKERELEDAEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1007 AHASSAGINDAVSKLESNQKEQLESLAeAHKRELEEISRSWEKKLNQQAEELQEKhEMELQEKEQELGDLKEKLATFSAE 1086
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREIEEER-KRRDKLTEEYAELKEELEDLRAELEEV-DKEFAETRDELKDYREKLEKLKRE 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1087 KEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEK 1166
Cdd:TIGR02169  401 INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1167 DKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELI------- 1239
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVveddava 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1240 EKCNE-----KIGIVTC----KIADCERQATKVKEAVII----------------------------------------- 1269
Cdd:TIGR02169  561 KEAIEllkrrKAGRATFlplnKMRDERRDLSILSEDGVIgfavdlvefdpkyepafkyvfgdtlvvedieaarrlmgkyr 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1270 ---------------------KMNKSVQQLQEKDNViKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELS 1328
Cdd:TIGR02169  641 mvtlegelfeksgamtggsraPRGGILFSRSEPAEL-QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1329 EninavtsLREDLQEKESEISTLNKTINELNVRLESM-VSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQek 1407
Cdd:TIGR02169  720 E-------IEKEIEQLEQEEEKLKERLEELEEDLSSLeQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-- 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1408 asalEQVDHCTAKLSEWKTKaqtrftqnHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENR 1487
Cdd:TIGR02169  791 ----SRIPEIQAELSKLEEE--------VSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1488 IEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDmeqkEVAWQLQQAEKVAFEKDSRLKEAEEKVL 1567
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE----ELEAQIEKKRKRLSELKAKLEALEEELS 934

                          810
                   ....*....|....*
gi 2024469763 1568 NLENEIGSLKAECEA 1582
Cdd:TIGR02169  935 EIEDPKGEDEEIPEE 949
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 276-1114 6.04e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 6.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  276 SVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKmKDLHMGEKTKLITQLRDAKNLIE 355
Cdd:pfam02463  189 IIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE-LLRDEQEEIESSKQEIEKEEEKL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  356 QLEQDKGMVIAETKRQMHETLEMKEEEVAQLRaRIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTE 435
Cdd:pfam02463  268 AQVLKENKEEEKEKKLQEEELKLLAKEEEELK-SELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKE 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  436 MDEKIKAVEKANEEERvnLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALE 515
Cdd:pfam02463  347 LEIKREAEEEEEEELE--KLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  516 KNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDS 595
Cdd:pfam02463  425 KKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESK 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  596 EKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKmrekqeqeiDTILKEKETVFRTHIEEMNEKTL 675
Cdd:pfam02463  505 ARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVE---------VSATADEVEERQKLVRALTELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  676 EKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKE 755
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  756 ELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARlmeaslsQQNTSNEQAKQYEEELAKLQQKLMDLKGEK 835
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQ-------LEIKKKEQREKEELKKLKLEAEELLADRVQ 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  836 LQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEH 915
Cdd:pfam02463  729 EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEE 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  916 VKKVQNEEMEELKQKLLATEERISTLQgdyeNKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQK 995
Cdd:pfam02463  809 ELKEEAELLEEEQLLIEQEEKIKEEEL----EELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  996 ESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGD 1075
Cdd:pfam02463  885 KDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 2024469763 1076 LKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEE 1114
Cdd:pfam02463  965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1065-1900 6.62e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.62  E-value: 6.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1065 ELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRnETLKQLQEELKQslAQMSALSNSESGLKAQLQKLEGDLS 1144
Cdd:TIGR02169  171 KKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKRE--YEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1145 QSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEE----KLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQL 1220
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1221 DaywksaevllqtksnELIEKCNEKIGIVTCKIADCERQATKVKEAVI---IKMNKSVQQLQEKDNVIKSMRDDIEGLVT 1297
Cdd:TIGR02169  328 E---------------AEIDKLLAEIEELEREIEEERKRRDKLTEEYAelkEELEDLRAELEEVDKEFAETRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1298 EKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEaaisl 1377
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY----- 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1378 lstqhQEERLQLINQVQELSSSVELLRQEKASALEQVDhcTAKLSEWKTKAQTRFTQN-----HETIKDLQSKLE----- 1447
Cdd:TIGR02169  468 -----EQELYDLKEEYDRVEKELSKLQRELAEAEAQAR--ASEERVRGGRAVEEVLKAsiqgvHGTVAQLGSVGEryata 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1448 -------------VSNTQATKKGEELDKLKE----------ELAQQGKDLDSLKSV--------LEEKENRIEKQ----- 1491
Cdd:TIGR02169  541 ievaagnrlnnvvVEDDAVAKEAIELLKRRKagratflplnKMRDERRDLSILSEDgvigfavdLVEFDPKYEPAfkyvf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1492 ------ESELTAELKIQAARVAELEEHIAQKT--------------SENDSLKEELKRYHEQKDMEQKEVAW---QLQQA 1548
Cdd:TIGR02169  621 gdtlvvEDIEAARRLMGKYRMVTLEGELFEKSgamtggsraprggiLFSRSEPAELQRLRERLEGLKRELSSlqsELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1549 EKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAIL--KSKEEELKELEERLNAENSCKLADLkKKAEQ 1626
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSslEQEIENVKSELKELEARIEELEEDL-HKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1627 KIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEknev 1706
Cdd:TIGR02169  780 ALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE---- 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1707 iksvqqtheekINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAK 1786
Cdd:TIGR02169  856 -----------IENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA 924

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1787 KYSLLVDEharcggdlASSREELKAKEQKNLGMENIMGDFQKKMQEkdavshsLEQKVKELEDnlakVNEVHKTEMEDRS 1866
Cdd:TIGR02169  925 KLEALEEE--------LSEIEDPKGEDEEIPEEELSLEDVQAELQR-------VEEEIRALEP----VNMLAIQEYEEVL 985

                          890       900       910
                   ....*....|....*....|....*....|....
gi 2024469763 1867 LKYEEnLKSLQQQLEERNDRLKALEENAEEKAKS 1900
Cdd:TIGR02169  986 KRLDE-LKEKRAKLEEERKAILERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1458-1846 7.83e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1458 EELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAarvaeleehiaqktsendsLKEELKRYheqkdmE 1537
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQA-------------------LLKEKREY------E 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1538 QKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMksailkskeeelkelEERLNAENSCKL 1617
Cdd:TIGR02169  225 GYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL---------------NKKIKDLGEEEQ 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1618 ADLKKKAEQKIGSIKReLVRQMEEKEQQLkQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKA 1697
Cdd:TIGR02169  290 LRVKEKIGELEAEIAS-LERSIAEKEREL-EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1698 AVEQEKNEVIKSVQQTHEEkINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGL 1777
Cdd:TIGR02169  368 DLRAELEEVDKEFAETRDE-LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDK 446

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763 1778 REELEEQAKKYSLLVDeharcggDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKE 1846
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAA-------DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRG 508
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 553-1188 8.24e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 61.39  E-value: 8.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  553 KLEEMHQEVETFKTRILELeSSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVsdiVEKHKEELENVKQQQEKLWTEKLQI 632
Cdd:pfam12128  242 EFTKLQQEFNTLESAELRL-SHLHFGYKSDETLIASRQEERQETSAELNQLL---RTLDDQWKEKRDELNGELSAADAAV 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  633 LQQQHVIEIEKMREKQEQEIDTilkeketvfrthieEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSK 712
Cdd:pfam12128  318 AKDRSELEALEDQHGAFLDADI--------------ETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSK 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  713 VGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAEL 792
Cdd:pfam12128  384 IKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELL 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  793 VQvsarlMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELE----LYISQVHELKQ 868
Cdd:pfam12128  464 LQ-----LENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDelelQLFPQAGTLLH 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  869 QLQEQS---DENTQKAMSLTQQYESQLK-DLQEEADKAKQTLTERENDIEHVKKVQNEEMEElkqkllATEERISTLQGD 944
Cdd:pfam12128  539 FLRKEApdwEQSIGKVISPELLHRTDLDpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEE------ELRERLDKAEEA 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  945 YENKLKRQENKMEKMKQKSKEMQETfKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAhASSAGINDAVSKLESN 1024
Cdd:pfam12128  613 LQSAREKQAAAEEQLVQANGELEKA-SREETFARTALKNARLDLRRLFDEKQSEKDKKNKALA-ERKDSANERLNSLEAQ 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1025 QK-----------EQLESLAE------AHKRELEEISRSWEKKLNQQAEELQEKHEMEL----QEKEQELGDLKEKLATF 1083
Cdd:pfam12128  691 LKqldkkhqawleEQKEQKREartekqAYWQVVEGALDAQLALLKAAIAARRSGAKAELkaleTWYKRDLASLGVDPDVI 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1084 SAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAI 1163
Cdd:pfam12128  771 AKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKA 850

                          650       660
                   ....*....|....*....|....*
gi 2024469763 1164 EEKDKARITELADKLKTLEEKLQTL 1188
Cdd:pfam12128  851 SEKQQVRLSENLRGLRCEMSKLATL 875
PTZ00121 PTZ00121
MAEBL; Provisional
 1484-2136 1.20e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.93  E-value: 1.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1484 KENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEE-LKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEA 1562
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEaKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1563 EEKVLNLENEIGSLKAECEAK---EREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKigsiKRELVRQM 1639
Cdd:PTZ00121  1157 ARKAEDARKAEEARKAEDAKKaeaARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAK----KAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1640 EE-KEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKI 1718
Cdd:PTZ00121  1233 EEaKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1719 NKLQKDlieknkllqkyeseqregidsllELQSKQEELLKKLECAEKRHREEQSVTEGLREEleEQAKKYSLLVDEHARC 1798
Cdd:PTZ00121  1313 EAKKAD-----------------------EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE--AEAAADEAEAAEEKAE 1367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1799 GGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVShslEQKVKELEDNLAKVNEVHKTEMEDRslKYEENLKSLQQ 1878
Cdd:PTZ00121  1368 AAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK---ADELKKAAAAKKKADEAKKKAEEKK--KADEAKKKAEE 1442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1879 QLEERNDRLKALEENAEEKAKSGLELQKllgdmqnQQKDLQAKLEEAeREKQKLRKDVNSLQKDLRTLRKEHQQEldiVK 1958
Cdd:PTZ00121  1443 AKKADEAKKKAEEAKKAEEAKKKAEEAK-------KADEAKKKAEEA-KKADEAKKKAEEAKKKADEAKKAAEAK---KK 1511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1959 KESLEEMEQKIRCEqediELKHSSTLKQLMREFNTQLAQKEMELETAvkETISKAQEVEselienhqiETTQLHKKIAEK 2038
Cdd:PTZ00121  1512 ADEAKKAEEAKKAD----EAKKAEEAKKADEAKKAEEKKKADELKKA--EELKKAEEKK---------KAEEAKKAEEDK 1576

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2039 DDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSENVTIAELQAQLAQKTTLVNDSKLKEQE 2118
Cdd:PTZ00121  1577 NMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE 1656

                          650
                   ....*....|....*...
gi 2024469763 2119 FKEQIHVLEDRLKNYEKK 2136
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDK 1674
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
811-989 1.87e-08

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 59.65  E-value: 1.87e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  811 NEQAKQYEEELAKLQQKL---------MDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKA 881
Cdd:COG3206    181 EEQLPELRKELEEAEAALeefrqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELL 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  882 MS-LTQQYESQLKDLQEEADKAKQTLTERENDIEHVKkvqnEEMEELKQKLLATEERI-STLQGDYENkLKRQENKMEKM 959
Cdd:COG3206    261 QSpVIQQLRAQLAELEAELAELSARYTPNHPDVIALR----AQIAALRAQLQQEAQRIlASLEAELEA-LQAREASLQAQ 335

                          170       180       190
                   ....*....|....*....|....*....|
gi 2024469763  960 KQKSKEMQETFKKKLAEQeSKLKKELENKQ 989
Cdd:COG3206    336 LAQLEARLAELPELEAEL-RRLEREVEVAR 364
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 731-1240 1.88e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 1.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  731 HKEEVEIMLKEHEISIQDVEKVLkEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLmEASLSQQNTS 810
Cdd:COG1196    233 KLRELEAELEELEAELEELEAEL-EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL-EQDIARLEER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  811 NEQAKQYEEElakLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYES 890
Cdd:COG1196    311 RRELEERLEE---LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  891 QLKDLQEEADKAKQ--TLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQE 968
Cdd:COG1196    388 LLEALRAAAELAAQleELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  969 tfkkkLAEQESKLKKELENKQLEFSQKESEfnAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSW- 1047
Cdd:COG1196    468 -----LLEEAALLEAALAELLEELAEAAAR--LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAl 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1048 EKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSN 1127
Cdd:COG1196    541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1128 SESGL----------KAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRE 1197
Cdd:COG1196    621 TLLGRtlvaarleaaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 2024469763 1198 NYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIE 1240
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 301-1246 2.57e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 59.68  E-value: 2.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  301 IRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIeqleQDKGMVIAETKRQMHETLEMKE 380
Cdd:TIGR01612  791 IKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDF----LNKVDKFINFENNCKEKIDSEH 866

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  381 EEVAQLRARIK-QITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLqtemDEKIKAVEKANE--EERVNLQQE 457
Cdd:TIGR01612  867 EQFAELTNKIKaEISDDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKV----DEYIKICENTKEsiEKFHNKQNI 942

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  458 LTRVKQEVVEIMKKSSE--------------DRVAELEKLHKEEMATKDQELNERLQaqerEFQEKMKAALEKNQSECL- 522
Cdd:TIGR01612  943 LKEILNKNIDTIKESNLieksykdkfdntliDKINELDKAFKDASLNDYEAKNNELI----KYFNDLKANLGKNKENMLy 1018

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  523 KTLQEQEQQESLALEELELQKK------------------AIQSECDKKLE----EMHQEVETFKTRILELESSLAKCSQ 580
Cdd:TIGR01612 1019 HQFDEKEKATNDIEQKIEDANKnipnieiaihtsiyniidEIEKEIGKNIEllnkEILEEAEINITNFNEIKEKLKHYNF 1098

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  581 DDKKRSEELSTLMDSEK-KQHNKEVSDIVEKHKEELENVKQQQEKLWTE-KLQI----------LQQQHVIEIekmrEKQ 648
Cdd:TIGR01612 1099 DDFGKEENIKYADEINKiKDDIKNLDQKIDHHIKALEEIKKKSENYIDEiKAQIndledvadkaISNDDPEEI----EKK 1174

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  649 EQEIDTILKEKETVFrthiEEMNektleKLDVKQTELETLSSELSEALKVRQDLEQELSEL-KSKVGEAKQEFEGKLEAE 727
Cdd:TIGR01612 1175 IENIVTKIDKKKNIY----DEIK-----KLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLfLEKIDEEKKKSEHMIKAM 1245

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  728 RNQHKEEVEIMLKEHEISIQ-DVEKVLKEELNQMKQSLEEKERLLEEAKT--------REQELKESAQRSEAELVQVSAR 798
Cdd:TIGR01612 1246 EAYIEDLDEIKEKSPEIENEmGIEMDIKAEMETFNISHDDDKDHHIISKKhdenisdiREKSLKIIEDFSEESDINDIKK 1325

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  799 LMEASLSQQNTSNEQAKQYEEELAKLQQKLmdlkgeklqlseqlvrtecQLNEVKNelelYISQVHELKQQLqEQSDENT 878
Cdd:TIGR01612 1326 ELQKNLLDAQKHNSDINLYLNEIANIYNIL-------------------KLNKIKK----IIDEVKEYTKEI-EENNKNI 1381

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  879 QKAMSLTQQYESQLKD---LQEEADKAKQTLTERENDiEHVKKVQneemeELKQKLLATEERISTLqgdyeNKLKRQENK 955
Cdd:TIGR01612 1382 KDELDKSEKLIKKIKDdinLEECKSKIESTLDDKDID-ECIKKIK-----ELKNHILSEESNIDTY-----FKNADENNE 1450

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  956 MEKMKQKSKEMqetfkkklaeQESKLKKELENKQlEFSQKESEFNAKMLEMAHASSAGINDAVSKlESNQKEQLESLAEA 1035
Cdd:TIGR01612 1451 NVLLLFKNIEM----------ADNKSQHILKIKK-DNATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQ 1518

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1036 HKRELEEIsrswekkLNQQAE-ELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEE 1114
Cdd:TIGR01612 1519 YKKDVTEL-------LNKYSAlAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKS 1591

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1115 LKQSLAQMSALSNSESGLkAQLQKLEGDLSQSLKEKSGLQEQISrQKAIEEKDkARITELADKLKTLEEKLQTLQSShsk 1194
Cdd:TIGR01612 1592 NKAAIDIQLSLENFENKF-LKISDIKKKINDCLKETESIEKKIS-SFSIDSQD-TELKENGDNLNSLQEFLESLKDQ--- 1665

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024469763 1195 dRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKI 1246
Cdd:TIGR01612 1666 -KKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEI 1716
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1654-2003 2.76e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 2.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1654 VRHLEQKVQEREAKIESLEEKMKSVRD-STELEREM-LQKIESTKAAVEQEKNEVIKSVQqtheekINKLQKDLIEKNKL 1731
Cdd:TIGR02168  167 ISKYKERRKETERKLERTRENLDRLEDiLNELERQLkSLERQAEKAERYKELKAELRELE------LALLVLRLEELREE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1732 LQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREeqsvtegLREELEEQAKKYSLLVDEHARCGGDLASSREELKA 1811
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE-------LEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1812 KEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVnevhktemedrslkyEENLKSLQQQLEERNDRLKALE 1891
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL---------------EAELEELEAELEELESRLEELE 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1892 ENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDL-RTLRKEHQQELDIVKKESLEEMEQKIR 1970
Cdd:TIGR02168  379 EQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLeEAELKELQAELEELEEELEELQEELER 458

                          330       340       350
                   ....*....|....*....|....*....|....
gi 2024469763 1971 CEQEDIELKHSST-LKQLMREFNTQLAQKEMELE 2003
Cdd:TIGR02168  459 LEEALEELREELEeAEQALDAAERELAQLQARLD 492
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
347-947 2.82e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 2.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  347 LRDAKNLIEQLEQDkgmVIAETKRQMHETLEMKEEEVAQLRARIkqittqgEELKEQKEKferaAFEELEKALGMAQRTE 426
Cdd:PRK02224   182 LSDQRGSLDQLKAQ---IEEKEEKDLHERLNGLESELAELDEEI-------ERYEEQREQ----ARETRDEADEVLEEHE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  427 EARKKLQT--EMDEKIKAVEKANEEERVNLQQELtRVKQEVVEIMKKSSEDRVAELE---------KLHKEEMATKDQEL 495
Cdd:PRK02224   248 ERREELETleAEIEDLRETIAETEREREELAEEV-RDLRERLEELEEERDDLLAEAGlddadaeavEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  496 NERLQAQEREFQEKMKAAleKNQSECLKTLQEQEQQESLALeelelqkkaiqSECDKKLEEMHQEVETFKTRILELESSL 575
Cdd:PRK02224   327 RDRLEECRVAAQAHNEEA--ESLREDADDLEERAEELREEA-----------AELESELEEAREAVEDRREEIEELEEEI 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  576 AKCSQ------DDKKRSEELSTLMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQhvieiekmrekqe 649
Cdd:PRK02224   394 EELRErfgdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQP------------- 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  650 qeidtiLKEKETVfrthieemnektlEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVgEAKQEFEGKLEaern 729
Cdd:PRK02224   461 ------VEGSPHV-------------ETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLV-EAEDRIERLEE---- 516

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  730 qHKEEVEIMLKEHEISIQDVEKVLkEELNQMKQsleekerlLEEAKTREQELKESAQRSEAElvqvSARLMEASLSQQNT 809
Cdd:PRK02224   517 -RREDLEELIAERRETIEEKRERA-EELRERAA--------ELEAEAEEKREAAAEAEEEAE----EAREEVAELNSKLA 582

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  810 SNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVrtecQLNEVKNELELYISQVHELKQQLQEQSDENtqkAMSLTQQYE 889
Cdd:PRK02224   583 ELKERIESLERIRTLLAAIADAEDEIERLREKRE----ALAELNDERRERLAEKRERKRELEAEFDEA---RIEEAREDK 655

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024469763  890 SQLKDLQEEADKAKQTLTERENDIE-HVKKVQNE--EMEELKQKLLATEERISTLQGDYEN 947
Cdd:PRK02224   656 ERAEEYLEQVEEKLDELREERDDLQaEIGAVENEleELEELRERREALENRVEALEALYDE 716
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1394-1896 3.34e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.90  E-value: 3.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1394 QELSSSVELLRQEKASALEQVDHCTAKlsewKTKAQTRFTQNHETIKDLQSKLEvsntQATKKGEELDKLKEELAQQGKD 1473
Cdd:PRK02224   202 KDLHERLNGLESELAELDEEIERYEEQ----REQARETRDEADEVLEEHEERRE----ELETLEAEIEDLRETIAETERE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1474 LDSLKSVLEEKENRIEKQESELTaELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAF 1553
Cdd:PRK02224   274 REELAEEVRDLRERLEELEEERD-DLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDAD 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1554 EKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAEN-SCKLADLKKKAEQKIGSIK 1632
Cdd:PRK02224   353 DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDfLEELREERDELREREAELE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1633 REL--VRQMEEKEQQLKQ---------------------DRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREmL 1689
Cdd:PRK02224   433 ATLrtARERVEEAEALLEagkcpecgqpvegsphvetieEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-I 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1690 QKIESTKAAVEQEKNEviksvqqtHEEKINKLQKDLIEKNKLLQKYESEQREgidsllelqskQEELLKKLECAEKRHRE 1769
Cdd:PRK02224   512 ERLEERREDLEELIAE--------RRETIEEKRERAEELRERAAELEAEAEE-----------KREAAAEAEEEAEEARE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1770 EQSVTEGLREELE---EQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQE-----KDAVSHSLE 1841
Cdd:PRK02224   573 EVAELNSKLAELKeriESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKREleaefDEARIEEAR 652

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763 1842 QKVKELEDNLAKVNEVHKTEMEDR------------SLKYEENLKSLQQQLEERNDRLKALEENAEE 1896
Cdd:PRK02224   653 EDKERAEEYLEQVEEKLDELREERddlqaeigavenELEELEELRERREALENRVEALEALYDEAEE 719
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 305-989 3.40e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 59.21  E-value: 3.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  305 KERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQmhETLEMKEEEVA 384
Cdd:TIGR00618  186 FAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQ--EEQLKKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  385 QLRARIKQITTQGEELKEQKEKFERAafEELEKALGMAQRTEEARKKLQ---TEMDEKIKAVEKANEEERVNLQQELTRV 461
Cdd:TIGR00618  264 QLRARIEELRAQEAVLEETQERINRA--RKAAPLAAHIKAVTQIEQQAQrihTELQSKMRSRAKLLMKRAAHVKQQSSIE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  462 KQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAqeREFQEKMKAALEKNQSECLKTLQEQEQQESLALEELEl 541
Cdd:TIGR00618  342 EQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHI--HTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSA- 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  542 qkkaiQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEvsdivekhkEELENVKQQ 621
Cdd:TIGR00618  419 -----FRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQL---------QTKEQIHLQ 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  622 QEKLWTEKLQILQQQHvieiEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQD 701
Cdd:TIGR00618  485 ETRKKAVVLARLLELQ----EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRAS 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  702 LEQELSELkskvgeakQEFEGKLEAERNQHKEEVEIMLKE-----HEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKT 776
Cdd:TIGR00618  561 LKEQMQEI--------QQSFSILTQCDNRSKEDIPNLQNItvrlqDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  777 REQELKESAQRSEAELVQVSARLM-----EASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNE 851
Cdd:TIGR00618  633 HLQQCSQELALKLTALHALQLTLTqervrEHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETH 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  852 VKN---ELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLT------ERENDIEHVKKVQNE 922
Cdd:TIGR00618  713 IEEydrEFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTaalqtgAELSHLAAEIQFFNR 792

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763  923 EMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQ 989
Cdd:TIGR00618  793 LREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSK 859
PTZ00121 PTZ00121
MAEBL; Provisional
 865-1708 3.90e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.00  E-value: 3.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  865 ELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGD 944
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  945 YENKLKRQENKMEKMKQKSKEMQETFKKKLAEQeskLKKELENKQLEFSQKESEFNaKMLEMAHASSAGINDAVSKLESN 1024
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAKKAEAARKAEEVRKAEE---LRKAEDARKAEAARKAEEER-KAEEARKAEDAKKAEAVKKAEEA 1235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1025 QKEQLESLAEAHKRELEEISRSWEKKLNQ--------QAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITR 1096
Cdd:PTZ00121  1236 KKDAEEAKKAEEERNNEEIRKFEEARMAHfarrqaaiKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1097 LKEEQVKRNETLKQLQEELKQSlAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELAD 1176
Cdd:PTZ00121  1316 KADEAKKKAEEAKKKADAAKKK-AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1177 KLKTLEEKLQTlQSSHSKDRENYEKKIEAFQQQETEVKelvaQLDAYWKSAEVllQTKSNELIEKCNEKIGIVTC-KIAD 1255
Cdd:PTZ00121  1395 EAKKKAEEDKK-KADELKKAAAAKKKADEAKKKAEEKK----KADEAKKKAEE--AKKADEAKKKAEEAKKAEEAkKKAE 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1256 CERQATKVKEAViiKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVT 1335
Cdd:PTZ00121  1468 EAKKADEAKKKA--EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1336 SLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQE----KASAL 1411
Cdd:PTZ00121  1546 KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEeakiKAEEL 1625

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1412 EQVDHCTAKLSEWKTKAQTRfTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQ 1491
Cdd:PTZ00121  1626 KKAEEEKKKVEQLKKKEAEE-KKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA 1704

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1492 EseltaELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLEN 1571
Cdd:PTZ00121  1705 E-----ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1572 EIgslkAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEE---------- 1641
Cdd:PTZ00121  1780 VI----EEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEadafekhkfn 1855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1642 ----------------KEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNE 1705
Cdd:PTZ00121  1856 knnengedgnkeadfnKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREE 1935


                   ...
gi 2024469763 1706 VIK 1708
Cdd:PTZ00121  1936 IIK 1938
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1197-1960 5.78e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 5.78e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1197 ENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNekigivtcKIADCERQATKVKEAVIIKMNKSVQ 1276
Cdd:pfam15921   81 EEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERD--------AMADIRRRESQSQEDLRNQLQNTVH 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1277 QLQEKDNVIKSMRDDIEglvTEKEQLQKEGGHQKQAATEKETCITQLRKELSENI------------NAVTSLREDLQEK 1344
Cdd:pfam15921  153 ELEAAKCLKEDMLEDSN---TQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIyehdsmstmhfrSLGSAISKILREL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1345 ESEISTLNKTINELNVRLESMVSltEKEAAISLLSTQHQEERLQLINQVQElsssvellrqekasaleQVDHCTAKLSEW 1424
Cdd:pfam15921  230 DTEISYLKGRIFPVEDQLEALKS--ESQNKIELLLQQHQDRIEQLISEHEV-----------------EITGLTEKASSA 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1425 KTKAQTrftqnhetikdLQSKLEVSNTQATKKGE----ELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELK 1500
Cdd:pfam15921  291 RSQANS-----------IQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELT 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1501 iqAARVaELEEHIAQKTSENDSLKEELKRYHEQK-----DMEQKEVAWQLQQAEKVAFEKDSR-LKEAEEKVLNLENEIG 1574
Cdd:pfam15921  360 --EART-ERDQFSQESGNLDDQLQKLLADLHKREkelslEKEQNKRLWDRDTGNSITIDHLRReLDDRNMEVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1575 SLKAECEAkerEFDQMKSAILKSKeeelkeleerlnaENSCKLADLKKKAEQKiGSIKRELVRQMEEKEQQLkQDRENQV 1654
Cdd:pfam15921  437 AMKSECQG---QMERQMAAIQGKN-------------ESLEKVSSLTAQLEST-KEMLRKVVEELTAKKMTL-ESSERTV 498

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1655 RHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEViksvqqtheekiNKLQKDLIEKNKLLQK 1734
Cdd:pfam15921  499 SDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTEC------------EALKLQMAEKDKVIEI 566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1735 YeseqREGIDSLLELQSKQEELLKKLECAEKRHREEqsvTEGLREELEE----QAKKYSLLVDEHARCggdlasSREELK 1810
Cdd:pfam15921  567 L----RQQIENMTQLVGQHGRTAGAMQVEKAQLEKE---INDRRLELQEfkilKDKKDAKIRELEARV------SDLELE 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1811 AKEQKNLGMENIMGDFQKKmQEKDAVSHSLEQKVKELeDNLAKVNEVHK-------TEMEDRSLKYEENLKSLQQQLEER 1883
Cdd:pfam15921  634 KVKLVNAGSERLRAVKDIK-QERDQLLNEVKTSRNEL-NSLSEDYEVLKrnfrnksEEMETTTNKLKMQLKSAQSELEQT 711

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1884 NDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLE-------EAEREKQKLRKDVNSLQKDLRTLRKEHQQ---E 1953
Cdd:pfam15921  712 RNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQfleeamtNANKEKHFLKEEKNKLSQELSTVATEKNKmagE 791


                   ....*..
gi 2024469763 1954 LDIVKKE 1960
Cdd:pfam15921  792 LEVLRSQ 798
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 161-999 6.92e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 6.92e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  161 YQVIQREKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSLLKQRLQNGQIGIE 240
Cdd:pfam02463  168 KRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLR 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  241 LPDPNNQSEPQVQSQTKEINAENIVEPGSNEGNEDSVKT----LETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKE 316
Cdd:pfam02463  248 DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEelklLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  317 ALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDKGMVIAETKR--QMHETLEMKEEEVAQLRARIKQIT 394
Cdd:pfam02463  328 KELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLesERLSSAAKLKEEELELKSEEEKEA 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  395 TQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSE 474
Cdd:pfam02463  408 QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  475 DRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKL 554
Cdd:pfam02463  488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLV 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  555 EEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQ 634
Cdd:pfam02463  568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  635 QQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVG 714
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  715 EAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQ 794
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  795 VSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQS 874
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  875 DENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQEN 954
Cdd:pfam02463  888 LESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL 967

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 2024469763  955 KMEKMkQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEF 999
Cdd:pfam02463  968 AKEEL-GKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAI 1011
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2162-2205 7.40e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.30  E-value: 7.40e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 2024469763  2162 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPADQTQKILER 2205
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1865-2130 1.07e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1865 RSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLlgdmQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLR 1944
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEEL----EAELAELEAELEELRLELEELELELEEAQAEEY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1945 TLRKE---HQQELDIVKKESLEEMEQKIRCEQEDIEL-KHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESEL 2020
Cdd:COG1196    292 ELLAElarLEQDIARLEERRRELEERLEELEEELAELeEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2021 IENHQIETTQLHKKIAEKDD-----DLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSENVTI 2095
Cdd:COG1196    372 AELAEAEEELEELAEELLEAlraaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 2024469763 2096 AELQAQLAQKTTLVNDSKLKEQEFKEQIHVLEDRL 2130
Cdd:COG1196    452 AELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
985-1585 1.18e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.36  E-value: 1.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  985 LENKQLEFSQKESEFNAKmlemahaSSAGINDAVSKLESNQKEQLESLAeaHKRELEEISRSWEKKLNQQAEELQEKHEm 1064
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEK-------EEKDLHERLNGLESELAELDEEIE--RYEEQREQARETRDEADEVLEEHEERRE- 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1065 ELQEKEQELGDLKEKLATFSAEKEgsrteitRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEgdls 1144
Cdd:PRK02224   252 ELETLEAEIEDLRETIAETERERE-------ELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELE---- 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1145 qslKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYW 1224
Cdd:PRK02224   321 ---DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELR 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1225 KSAEVLLQTKSNeliekcnekigivtckiadcerqATKVKEAVIIKMNKSVQQLQEKDNVIKSMRDDIEglvtEKEQLQK 1304
Cdd:PRK02224   398 ERFGDAPVDLGN-----------------------AEDFLEELREERDELREREAELEATLRTARERVE----EAEALLE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1305 EGghqkqaatEKETCITQLrkELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLstqhqE 1384
Cdd:PRK02224   451 AG--------KCPECGQPV--EGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERL-----E 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1385 ERLQLInqvqelsssVELLRQEKASALEQvdhctaklsewktkaQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLK 1464
Cdd:PRK02224   516 ERREDL---------EELIAERRETIEEK---------------RERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR 571

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1465 EELAQQGKDLDSLKSVLeEKENRIEkqesELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEV--- 1541
Cdd:PRK02224   572 EEVAELNSKLAELKERI-ESLERIR----TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFdea 646

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 2024469763 1542 -----AWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKER 1585
Cdd:PRK02224   647 rieeaREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE 695
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 786-1723 1.47e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 56.98  E-value: 1.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  786 QRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVkNELELYISQVHE 865
Cdd:TIGR00606  198 QGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKI-MKLDNEIKALKS 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  866 LKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQgdy 945
Cdd:TIGR00606  277 RKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQ--- 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  946 enkLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKEsefnaKMLEMAHASSAGINDAVSKLESNQ 1025
Cdd:TIGR00606  354 ---LQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIE-----RQEDEAKTAAQLCADLQSKERLKQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1026 KE--QLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEME-----LQEKEQELGDLKEKL--ATFSAEKEGSRTEITR 1096
Cdd:TIGR00606  426 EQadEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEgssdrILELDQELRKAERELskAEKNSLTETLKKEVKS 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1097 LKEEQVKRNETLKQLQEELKQ------SLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKAR 1170
Cdd:TIGR00606  506 LQNEKADLDRKLRKLDQEMEQlnhhttTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKE 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1171 ITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVkelvaqLDAYWKSAEVLLQTKSNELIEKCNEKIGIVT 1250
Cdd:TIGR00606  586 INQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL------FDVCGSQDEESDLERLKEEIEKSSKQRAMLA 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1251 CKIADCERQATKVKEAV---------IIKMNKSVQQLQEK-DNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCI 1320
Cdd:TIGR00606  660 GATAVYSQFITQLTDENqsccpvcqrVFQTEAELQEFISDlQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSII 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1321 TQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSS-- 1398
Cdd:TIGR00606  740 DLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsd 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1399 ---SVELLRQEKASALEQVDHCTAKLSEWKTKAQTRftqnHETIKDLQSKLEVSNTQATKKGEELDK---LKEELAQQGK 1472
Cdd:TIGR00606  820 ldrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQ----QEQIQHLKSKTNELKSEKLQIGTNLQRrqqFEEQLVELST 895

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1473 DLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYH-EQKDMEQkevawqlqqaeKV 1551
Cdd:TIGR00606  896 EVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHgYMKDIEN-----------KI 964

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1552 AFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSI 1631
Cdd:TIGR00606  965 QDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEM 1044

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1632 KRELVRQMEEKEQQLKQD-----RENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAA---VEQEK 1703
Cdd:TIGR00606 1045 GQMQVLQMKQEHQKLEENidlikRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTELVnkdLDIYY 1124

                          970       980
                   ....*....|....*....|
gi 2024469763 1704 NEVIKSVQQTHEEKINKLQK 1723
Cdd:TIGR00606 1125 KTLDQAIMKFHSMKMEEINK 1144
mukB PRK04863
chromosome partition protein MukB;
816-1534 1.49e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 57.27  E-value: 1.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  816 QYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQeQSDENTQKAMSLTQQYEsQLKDL 895
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQ-AASDHLNLVQTALRQQE-KIERY 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  896 QEEADKakqtLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQG---DYENKLKRQENK----------MEKMKQ- 961
Cdd:PRK04863   354 QADLEE----LEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSqlaDYQQALDVQQTRaiqyqqavqaLERAKQl 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  962 ---------KSKEMQETFKKKLAEQESKLKkELENKqLEFSQKESEFNAKMLEMAHASSAGI------NDAVSKL----- 1021
Cdd:PRK04863   430 cglpdltadNAEDWLEEFQAKEQEATEELL-SLEQK-LSVAQAAHSQFEQAYQLVRKIAGEVsrseawDVARELLrrlre 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1022 ESNQKEQLESLAEAHK---------RELEEISRSWEKKLNQQ------AEELQEKHEMELQEKEQELGDLKEKLATFSAE 1086
Cdd:PRK04863   508 QRHLAEQLQQLRMRLSeleqrlrqqQRAERLLAEFCKRLGKNlddedeLEQLQEELEARLESLSESVSEARERRMALRQQ 587

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1087 KEGSRTEITRLKE---EQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAI 1163
Cdd:PRK04863   588 LEQLQARIQRLAArapAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSQP 667

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1164 EEKDKARITELADK------------------------------------LKTLEEKLQTLQ------------------ 1189
Cdd:PRK04863   668 GGSEDPRLNALAERfggvllseiyddvsledapyfsalygparhaivvpdLSDAAEQLAGLEdcpedlyliegdpdsfdd 747

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1190 SSHSKD---------------------------RENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKS------- 1235
Cdd:PRK04863   748 SVFSVEelekavvvkiadrqwrysrfpevplfgRAAREKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSrfigshl 827

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1236 --------NELIEKCNEKIGIVTCKIADCERQATKVKEAViIKMNKSVQQLQEKDNVIKSMRDdiEGLVTEKEQLQKegg 1307
Cdd:PRK04863   828 avafeadpEAELRQLNRRRVELERALADHESQEQQQRSQL-EQAKEGLSALNRLLPRLNLLAD--ETLADRVEEIRE--- 901

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1308 hQKQAATEKETCITQLRKELSENINAVTSLREDLQEKE---SEISTLNKTINELNVRLESMVSLTEKEAAISLlstqhqE 1384
Cdd:PRK04863   902 -QLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEqlkQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSY------E 974

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1385 ERLQLINQVQELsssVELLRQEKASALEQVDHCTAKLsewkTKAQTRFTQNHETIKDLQSKLEVsntqatkKGEELDKLK 1464
Cdd:PRK04863   975 DAAEMLAKNSDL---NEKLRQRLEQAEQERTRAREQL----RQAQAQLAQYNQVLASLKSSYDA-------KRQMLQELK 1040

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024469763 1465 EELAQQGKDLDslksvlEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKR----YHEQK 1534
Cdd:PRK04863  1041 QELQDLGVPAD------SGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKlerdYHEMR 1108
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
453-1114 1.57e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.97  E-value: 1.57e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  453 NLQQELTRVKQEVVEIMKKSSEDRVAELEklhkeematkdQELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQE 532
Cdd:PRK02224   184 DQRGSLDQLKAQIEEKEEKDLHERLNGLE-----------SELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  533 SLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLakcsqDDKKRSEELSTLMDsekkqhnkevsDIVEKHK 612
Cdd:PRK02224   253 LETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER-----DDLLAEAGLDDADA-----------EAVEARR 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  613 EELENVKQQ-QEKLWTEKLQIlqQQHVIEIEKMREKQEQeidtilkeketvfrthIEEMNEKTLEKLDVKQTELETLSSE 691
Cdd:PRK02224   317 EELEDRDEElRDRLEECRVAA--QAHNEEAESLREDADD----------------LEERAEELREEAAELESELEEAREA 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  692 LSEALKVRQDLEQELSELKSKVGEAKQEFEG--KLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEelnqmkqslEEKER 769
Cdd:PRK02224   379 VEDRREEIEELEEEIEELRERFGDAPVDLGNaeDFLEELREERDELREREAELEATLRTARERVEE---------AEALL 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  770 LLEEAKTREQELKESAQRSEAElvqvsarlmeaslsqqnTSNEQAKQYEEELAKLQQKLMDLKgEKLQLSEQLVRTECQL 849
Cdd:PRK02224   450 EAGKCPECGQPVEGSPHVETIE-----------------EDRERVEELEAELEDLEEEVEEVE-ERLERAEDLVEAEDRI 511

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  850 NEVKNELELyisqVHELKQQLQEQSDENTQKAMSLTQQYEsQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQ 929
Cdd:PRK02224   512 ERLEERRED----LEELIAERRETIEEKRERAEELRERAA-ELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKE 586

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  930 KLLATeERISTLQGDYENKLKRQENKMEKMKQkskemqetfkkkLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHA 1009
Cdd:PRK02224   587 RIESL-ERIRTLLAAIADAEDEIERLREKREA------------LAELNDERRERLAEKRERKRELEAEFDEARIEEARE 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1010 SSAGINDAVSKLEsnqkEQLESLAEAHKRELEEISrswekKLNQQAEELQekhemELQEKEQELGDLKEKLATFSAEKEG 1089
Cdd:PRK02224   654 DKERAEEYLEQVE----EKLDELREERDDLQAEIG-----AVENELEELE-----ELRERREALENRVEALEALYDEAEE 719

                          650       660
                   ....*....|....*....|....*.
gi 2024469763 1090 SRTEITRLKEEQVKRN-ETLKQLQEE 1114
Cdd:PRK02224   720 LESMYGDLRAELRQRNvETLERMLNE 745
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 410-1085 1.76e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 56.77  E-value: 1.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  410 AAFEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEimkkssedrvAELEKLHKEEMA 489
Cdd:pfam12128  248 QEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDE----------LNGELSAADAAV 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  490 TKDQELNERLQAQEREFQ----EKMKAALEKN---QSEC---LKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQ 559
Cdd:pfam12128  318 AKDRSELEALEDQHGAFLdadiETAAADQEQLpswQSELenlEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKD 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  560 EVETFKTrilELESSLAKCSQDDKKRSEELSTLMDsekkQHNKEVSDIVEKHKEELENVK-QQQEKLWTEKLQILQQQHV 638
Cdd:pfam12128  398 KLAKIRE---ARDRQLAVAEDDLQALESELREQLE----AGKLEFNEEEYRLKSRLGELKlRLNQATATPELLLQLENFD 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  639 IEIEKMREKQEQEIDTI--LKEKETVFRTHIEEMNEK-TLEKLDVKQ-----------------TELETLSSE------- 691
Cdd:pfam12128  471 ERIERAREEQEAANAEVerLQSELRQARKRRDQASEAlRQASRRLEErqsaldelelqlfpqagTLLHFLRKEapdweqs 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  692 ----LSEALKVRQDLEQELSElkSKVGEAKQEFEGKLEAER------NQHKEEVEIMLKEHEISIQ---DVEKVLKEELN 758
Cdd:pfam12128  551 igkvISPELLHRTDLDPEVWD--GSVGGELNLYGVKLDLKRidvpewAASEEELRERLDKAEEALQsarEKQAAAEEQLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  759 QMKqsleekerlleeAKTREQELKESAQRseaelvqvsARLMEASLSQQNTSNEQakqyEEELAKLQQKlmdLKGEKLQL 838
Cdd:pfam12128  629 QAN------------GELEKASREETFAR---------TALKNARLDLRRLFDEK----QSEKDKKNKA---LAERKDSA 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  839 SEQLVRTECQLNEVKNELELYisqvhelKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKqtLTERENDIEHVKK 918
Cdd:pfam12128  681 NERLNSLEAQLKQLDKKHQAW-------LEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAI--AARRSGAKAELKA 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  919 VQNEEMEELKqKLLATEERISTLQGDYEN---KLKRQENKMEKMKQKSKEMQETF---KKKLAEQESKLKKELENKQLEF 992
Cdd:pfam12128  752 LETWYKRDLA-SLGVDPDVIAKLKREIRTlerKIERIAVRRQEVLRYFDWYQETWlqrRPRLATQLSNIERAISELQQQL 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  993 SQKESE---FNAKmLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEK 1069
Cdd:pfam12128  831 ARLIADtklRRAK-LEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESV 909

                          730
                   ....*....|....*.
gi 2024469763 1070 EQELGDLKEKLATFSA 1085
Cdd:pfam12128  910 KKYVEHFKNVIADHSG 925
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-672 2.28e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 2.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  309 AQLTNEKEALQEQLEERLQELEKMKDlhmgEKTKLITQLRDAKNLIEQLEQDKgmviaetkRQMHETLEMKEEEVAQLRA 388
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRK----ELEELEEELEQLRKELEELSRQI--------SALRKDLARLEAEVEQLEE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  389 RIKQITTQGEELKEQKEKFEraafEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKANE-----EERVNLQQELTRVKQ 463
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELE----ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREaldelRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  464 EVVEIMKKSSEDRVAELEKLHKE-EMATKDQELNERLQAQEREFQEKMKAALEKN------QSECLKTLQEQEQQESLAL 536
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQiEELSEDIESLAAEIEELEELIEELESELEALlnerasLEEALALLRSELEELSEEL 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  537 EELELQKKAIQ---SECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHK- 612
Cdd:TIGR02168  904 RELESKRSELRrelEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKe 983

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763  613 ---------EELENVKQQQEKLWTEKLqilqqqhviEIEKMREKQEQEIDTILKEKETVFRTHIEEMNE 672
Cdd:TIGR02168  984 lgpvnlaaiEEYEELKERYDFLTAQKE---------DLTEAKETLEEAIEEIDREARERFKDTFDQVNE 1043
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 609-1221 3.37e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.89  E-value: 3.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  609 EKHKEELENVKQQQEKLWTEKLQILQQQHViEIEKMReKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETL 688
Cdd:pfam15921  141 EDLRNQLQNTVHELEAAKCLKEDMLEDSNT-QIEQLR-KMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSL 218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  689 SSELSEALKvrqDLEQELSELKSKVGEA-------KQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMK 761
Cdd:pfam15921  219 GSAISKILR---ELDTEISYLKGRIFPVedqlealKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQAN 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  762 QSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEAslsqQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQ 841
Cdd:pfam15921  296 SIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA----KRMYEDKIEELEKQLVLANSELTEARTERDQFSQE 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  842 LVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSL-------------TQQYESQLKDLQEEA--------- 899
Cdd:pfam15921  372 SGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIdhlrrelddrnmeVQRLEALLKAMKSECqgqmerqma 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  900 -----DKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQgDYENKLKRQENKMEKMKQKSKEMQETFKKKL 974
Cdd:pfam15921  452 aiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVS-DLTASLQEKERAIEATNAEITKLRSRVDLKL 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  975 AEQEsklkkELENKQLEFSQKESEFNAKMLEMAHassagiNDAVSKLESNQKEQLESLAEAHKRELEEI---SRSWEKKL 1051
Cdd:pfam15921  531 QELQ-----HLKNEGDHLRNVQTECEALKLQMAE------KDKVIEILRQQIENMTQLVGQHGRTAGAMqveKAQLEKEI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1052 NQQAEELQE------KHEMELQEKEQELGDL---KEKLATFSAEK------------------EGSRTEITRLKEEQVKR 1104
Cdd:pfam15921  600 NDRRLELQEfkilkdKKDAKIRELEARVSDLeleKVKLVNAGSERlravkdikqerdqllnevKTSRNELNSLSEDYEVL 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1105 NETLKQLQEELKQSLAQMS-ALSNSESGL---KAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADK--- 1177
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKmQLKSAQSELeqtRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAmtn 759

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024469763 1178 -------LKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLD 1221
Cdd:pfam15921  760 ankekhfLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
280-718 4.93e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.07  E-value: 4.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  280 LETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQlEERLQELEKMKDLHMgEKTKLITQLRDAKNLIEQLEQ 359
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEK-VKELKELKEKAEEYI-KLSEFYEEYLDELREIEKRLS 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  360 DKGMVIAETKRQMHEtLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMDEK 439
Cdd:PRK03918   318 RLEEEINGIEERIKE-LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEEL 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  440 IKAVEKAnEEERVNLQQELTRVKQEVVEIMKKSSEDRVA---------ELEKLHKEEMATKDQELNERLQAQEREFQEKM 510
Cdd:PRK03918   397 EKAKEEI-EEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKE 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  511 KAALE---------KNQSECLKTLQEQEQQESLALEELELQKKAIQSEcDKKLEEMHQEVETFKTRILELESSLAKCSQD 581
Cdd:PRK03918   476 RKLRKelrelekvlKKESELIKLKELAEQLKELEEKLKKYNLEELEKK-AEEYEKLKEKLIKLKGEIKSLKKELEKLEEL 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  582 DKKRSEELSTLMDSEKKQHN-----------------KEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKM 644
Cdd:PRK03918   555 KKKLAELEKKLDELEEELAEllkeleelgfesveeleERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEE 634

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024469763  645 REKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQ 718
Cdd:PRK03918   635 LAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
PRK12704 PRK12704
phosphodiesterase; Provisional
 901-1069 5.44e-07

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 54.78  E-value: 5.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  901 KAKQTLTERENDIEHVKKVQNEEMEELKQ-KLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQEs 979
Cdd:PRK12704    28 IAEAKIKEAEEEAKRILEEAKKEAEAIKKeALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLE- 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  980 KLKKELENKQLEFSQKESEFNAKMLEmahassagindaVSKLESNQKEQLESLA-----EAHKRELEEIsrswEKKLNQQ 1054
Cdd:PRK12704   107 KREEELEKKEKELEQKQQELEKKEEE------------LEELIEEQLQELERISgltaeEAKEILLEKV----EEEARHE 170

                          170
                   ....*....|....*
gi 2024469763 1055 AEELQEKHEMELQEK 1069
Cdd:PRK12704   171 AAVLIKEIEEEAKEE 185
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 732-1524 7.33e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 7.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  732 KEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELkesaQRSEAELVQVSARLMEASLSQQNTSN 811
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM----QMERDAMADIRRRESQSQEDLRNQLQ 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  812 EQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELelyISQVHELKQQLQEQSDENTQKAMSLTQQYESQ 891
Cdd:pfam15921  149 NTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL---VDFEEASGKKIYEHDSMSTMHFRSLGSAISKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  892 LKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKllaTEERISTLQGDYE--------------NKLKRQENKME 957
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQ---HQDRIEQLISEHEveitgltekassarSQANSIQSQLE 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  958 KMKQKSKEMQETFKKKLAEQE---SKLKKELENKQLEFSQKESEFNAKML----EMAHASSAgiNDAVSKLESNQKEQLE 1030
Cdd:pfam15921  303 IIQEQARNQNSMYMRQLSDLEstvSQLRSELREAKRMYEDKIEELEKQLVlansELTEARTE--RDQFSQESGNLDDQLQ 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1031 S-LAEAHKRELEeisRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLK 1109
Cdd:pfam15921  381 KlLADLHKREKE---LSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKN 457

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1110 QLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKlktLEEKLQTLQ 1189
Cdd:pfam15921  458 ESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSR---VDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1190 ssHSKDRENYekkieaFQQQETEVKELVAQLDAYWKSAEVLLQTKSN--ELIEKCNEKIGIVTCKIADCERQAT----KV 1263
Cdd:pfam15921  535 --HLKNEGDH------LRNVQTECEALKLQMAEKDKVIEILRQQIENmtQLVGQHGRTAGAMQVEKAQLEKEINdrrlEL 606

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1264 KEAVIIKmnksvqqlQEKDNVIKSMRDDIEGLVTEKEQLQKEGghqkqaaTEKETCITQLRKELSENINAVTSLREDLQE 1343
Cdd:pfam15921  607 QEFKILK--------DKKDAKIRELEARVSDLELEKVKLVNAG-------SERLRAVKDIKQERDQLLNEVKTSRNELNS 671

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1344 KESEISTLNKTINELNVRLEsmvsltekeaaisllsTQHQEERLQLINQVQELSSSVELLRqekasALEQVDHCTAKLSe 1423
Cdd:pfam15921  672 LSEDYEVLKRNFRNKSEEME----------------TTTNKLKMQLKSAQSELEQTRNTLK-----SMEGSDGHAMKVA- 729

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1424 wkTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKS----------VLEEKENRIEKQES 1493
Cdd:pfam15921  730 --MGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATeknkmageleVLRSQERRLKEKVA 807

                          810       820       830
                   ....*....|....*....|....*....|.
gi 2024469763 1494 ELTAELKIQAARVAELEEHIAQKTSENDSLK 1524
Cdd:pfam15921  808 NMEVALDKASLQFAECQDIIQRQEQESVRLK 838
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1623-2118 7.33e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 7.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1623 KAEQKIGSIKRELVRQMEEKEQQLKQ--DRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVE 1700
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRteNIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1701 Q--EKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYEsEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLR 1778
Cdd:PRK03918   242 EleKELESLEGSKRKLEEKIRELEERIEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1779 EELEEQAKKYSLLVDEHARCGgDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVH 1858
Cdd:PRK03918   321 EEINGIEERIKELEEKEERLE-ELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKA 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1859 KTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLEL-----QKLLGDMQNQQKDLQAKLEEAEREKQKLR 1933
Cdd:PRK03918   400 KEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELteehrKELLEEYTAELKRIEKELKEIEEKERKLR 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1934 KDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQL------AQKEMELETAVK 2007
Cdd:PRK03918   480 KELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIkslkkeLEKLEELKKKLA 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2008 ETISKAQEVESELIENHQIETTQLHKKIAEKDDDLKRTVKKYEEILEAREEemttkVHELQTQLEELQKEYKQRMAEKDH 2087
Cdd:PRK03918   560 ELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDA-----EKELEREEKELKKLEEELDKAFEE 634

                          490       500       510
                   ....*....|....*....|....*....|.
gi 2024469763 2088 RNSENVTIAELQAQLAQKTTLVNDSKLKEQE 2118
Cdd:PRK03918   635 LAETEKRLEELRKELEELEKKYSEEEYEELR 665
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1037-1585 7.71e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 7.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1037 KRELEEISRSWEKKLNQQA--EELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRteitrlkeeqvKRNETLKQLQEE 1114
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTEniEELIKEKEKELEEVLREINEISSELPELREELEKLE-----------KEVKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1115 LKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKA--RITELADKLKTLEEKLQTLQSSH 1192
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1193 SKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLlqtksneliEKCNEKIGIVTCKIADCERQATKVKEAVIIKMN 1272
Cdd:PRK03918   320 EEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL---------EERHELYEEAKAKKEELERLKKRLTGLTPEKLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1273 KSVQQLQEKDnviKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKE-------TCITQLRKELSENInaVTSLREDLQEKE 1345
Cdd:PRK03918   391 KELEELEKAK---EEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpVCGRELTEEHRKEL--LEEYTAELKRIE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1346 SEISTLNKTINELNVRLESMVSLTEKEAAISLLstqhqeerLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEWK 1425
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVLKKESELIKL--------KELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKL 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1426 TKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQG-KDLDSLKSVLEEKE------NRIEKQESELTAE 1498
Cdd:PRK03918   538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneyLELKDAEKELERE 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1499 LKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQK----DMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIG 1574
Cdd:PRK03918   618 EKELKKLEEELDKAFEELAETEKRLEELRKELEELEkkysEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLE 697

                          570
                   ....*....|.
gi 2024469763 1575 SLKAECEAKER 1585
Cdd:PRK03918   698 KLKEELEEREK 708
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1455-1949 1.21e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.91  E-value: 1.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1455 KKGEELDKLKEELAQQGKDLDSL---KSVLEEKENRIEKQESELTAELKIQAARVAELEEhIAQKTSENDSLKEELKRYH 1531
Cdd:PRK03918   228 KEVKELEELKEEIEELEKELESLegsKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYEEYL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1532 EQKDMEQKEVAWQLQQAEKV------AFEKDSRLKEAEEKVLNLENEIGSLKA------ECEAKEREFDQMKSAILKSKE 1599
Cdd:PRK03918   307 DELREIEKRLSRLEEEINGIeerikeLEEKEERLEELKKKLKELEKRLEELEErhelyeEAKAKKEELERLKKRLTGLTP 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1600 EELKELEERLNAENScKLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVR 1679
Cdd:PRK03918   387 EKLEKELEELEKAKE-EIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1680 DSTELEREMLQKIESTKAAVEQE-KNEVIKSVQQTHEEKINKLQKDLIEKN-KLLQKYESEQREGIDSLLELQSKQEELL 1757
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVlKKESELIKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1758 KKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVS 1837
Cdd:PRK03918   546 KELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLE 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1838 HSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKD 1917
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705

                          490       500       510
                   ....*....|....*....|....*....|..
gi 2024469763 1918 LQAKLEEAEREKqKLRKDVNSLQKDLRTLRKE 1949
Cdd:PRK03918   706 REKAKKELEKLE-KALERVEELREKVKKYKAL 736
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1577-1936 1.23e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1577 KAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKigsikrELVRQMEEKEQQLKQdRENQVRH 1656
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGY------ELLKEKEALERQKEA-IERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1657 LEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYE 1736
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1737 SEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHArcggdlassrEELKAKEQKN 1816
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK----------DYREKLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1817 LGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVhKTEMEDRSL---KYEENLKSLQQQLEERNDRLKALEEN 1893
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL-EEEKEDKALeikKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 2024469763 1894 aeekaksglelqklLGDMQNQQKDLQAKLEEAEREKQKLRKDV 1936
Cdd:TIGR02169  478 --------------YDRVEKELSKLQRELAEAEAQARASEERV 506
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1309-1515 1.28e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 1.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1309 QKQAATEKEtcITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESM-VSLTEKEAAISLLSTQHQEERL 1387
Cdd:COG4942     27 AELEQLQQE--IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeAELAELEKEIAELRAELEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1388 QLINQVQEL------SSSVELLRQEKASALEQVDHCTAKLSEWKTKAQtrftqnhETIKDLQSKLEVSNTQATKKGEELD 1461
Cdd:COG4942    105 ELAELLRALyrlgrqPPLALLLSPEDFLDAVRRLQYLKYLAPARREQA-------EELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024469763 1462 KLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQ 1515
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
275-741 1.30e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  275 DSVKTLETLNQRVKRQENLLQRCKEmirsHKERCAQLTNEKEALQEQLEERLQELEKMK----DLHMG------EKTKLI 344
Cdd:PRK02224   203 DLHERLNGLESELAELDEEIERYEE----QREQARETRDEADEVLEEHEERREELETLEaeieDLRETiaeterEREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  345 TQLRDAKNLIEQLEQDKGMVIAETKR---------QMHETLEMKEEEVA----QLRARIKQITTQGEELKEQKEKFE--- 408
Cdd:PRK02224   279 EEVRDLRERLEELEEERDDLLAEAGLddadaeaveARREELEDRDEELRdrleECRVAAQAHNEEAESLREDADDLEera 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  409 ---RAAFEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKA----------NEEERVNLQQELTRVKQEVVEIMK--KSS 473
Cdd:PRK02224   359 eelREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapvdlgnAEDFLEELREERDELREREAELEAtlRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  474 EDRVAELEKLHKE----------------EMATKDQELNERLQAqEREFQEKMKAALEKnQSECLKTLQEQEQQESLALE 537
Cdd:PRK02224   439 RERVEEAEALLEAgkcpecgqpvegsphvETIEEDRERVEELEA-ELEDLEEEVEEVEE-RLERAEDLVEAEDRIERLEE 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  538 ELE------LQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLmdSEKKQHNKEVSDIVEKH 611
Cdd:PRK02224   517 RREdleeliAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAEL--NSKLAELKERIESLERI 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  612 KE---ELENVKQQQEKLwTEKLQILQQQHVIEIEKMREKQEQ------EID----TILKEKETVFRTHIEEMNEKtLEKL 678
Cdd:PRK02224   595 RTllaAIADAEDEIERL-REKREALAELNDERRERLAEKRERkreleaEFDeariEEAREDKERAEEYLEQVEEK-LDEL 672

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024469763  679 DVKQTELETLSSELSEALKVRQDLEQELSELKSKVG---------EAKQEFEGKLEAE-RNQHKEEVEIMLKE 741
Cdd:PRK02224   673 REERDDLQAEIGAVENELEELEELRERREALENRVEalealydeaEELESMYGDLRAElRQRNVETLERMLNE 745
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1633-2091 1.57e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1633 RELVRQMEEKEQQLKQDRENQvrhLEQKVQEREAKIESLEEKmksvrdsTELEREMLQKIESTKAAVEQEKNEViksvqQ 1712
Cdd:PRK02224   190 DQLKAQIEEKEEKDLHERLNG---LESELAELDEEIERYEEQ-------REQARETRDEADEVLEEHEERREEL-----E 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1713 THEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKL-------ECAEKRHREEQSVTEGLREELEEQA 1785
Cdd:PRK02224   255 TLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAglddadaEAVEARREELEDRDEELRDRLEECR 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1786 KKYSllvdehaRCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNE------VHK 1859
Cdd:PRK02224   335 VAAQ-------AHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdapVDL 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1860 TEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEkAKSGLELQKLLGDMQNQQKDLQA-KLEEAEREKQKLRKDVNS 1938
Cdd:PRK02224   408 GNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEAGKCPECGQPVEGSPHVeTIEEDRERVEELEAELED 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1939 LQKDLRTLRKEHQQELDIVKKES-LEEMEQKIRCEQEDIELKHSSTLKQlmREFNTQLAQKEMELETAVKETISKAQEVE 2017
Cdd:PRK02224   487 LEEEVEEVEERLERAEDLVEAEDrIERLEERREDLEELIAERRETIEEK--RERAEELRERAAELEAEAEEKREAAAEAE 564

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 2018 SElIENHQIETTQLHKKIAEKDDDLKRTVK-KYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSE 2091
Cdd:PRK02224   565 EE-AEEAREEVAELNSKLAELKERIESLERiRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRE 638
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1157-1783 1.66e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1157 ISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQ--TK 1234
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSdlSK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1235 SNELIEKCNEKIGIVTCKIADCERQATKVKEaviiKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAAT 1314
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKK----NIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1315 EKETCITQLRKELS----------ENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVS-LTEKEAAISLLSTQHQ 1383
Cdd:TIGR04523  184 NIQKNIDKIKNKLLklelllsnlkKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTeISNTQTQLNQLKDEQN 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1384 EERLQLINQVQELSSSVELLRQEKasalEQVDHCTAKLSEWKTKAQTRFTQN-HETIKDLQSKLEVSNTQATKKGEELDK 1462
Cdd:TIGR04523  264 KIKKQLSEKQKELEQNNKKIKELE----KQLNQLKSEISDLNNQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQ 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1463 LKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKiqaarvaeleehiaqktsENDSLKEELKRYHEQKdmeqKEVA 1542
Cdd:TIGR04523  340 LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK------------------ENQSYKQEIKNLESQI----NDLE 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1543 WQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCK-LADLK 1621
Cdd:TIGR04523  398 SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKvLSRSI 477

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1622 KKAEQKIGSIKRELVRQMEEKEQ--QLKQDRENQVRHLEQKVQEREAKIESLE-EKMKSVRDSTELEREMLQ-KIESTKA 1697
Cdd:TIGR04523  478 NKIKQNLEQKQKELKSKEKELKKlnEEKKELEEKVKDLTKKISSLKEKIEKLEsEKKEKESKISDLEDELNKdDFELKKE 557

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1698 AVEQEKNEVIKSVQQTHEEKiNKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGL 1777
Cdd:TIGR04523  558 NLEKEIDEKNKEIEELKQTQ-KSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636


                   ....*.
gi 2024469763 1778 REELEE 1783
Cdd:TIGR04523  637 KSKKNK 642
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1025-1533 1.70e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 1.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1025 QKEQLESLAEAHKR------------ELEEISRSWekklnqQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRT 1092
Cdd:COG4913    250 QIELLEPIRELAERyaaarerlaeleYLRAALRLW------FAQRRLELLEAELEELRAELARLEAELERLEARLDALRE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1093 EITRLkEEQVKRN--ETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKAR 1170
Cdd:COG4913    324 ELDEL-EAQIRGNggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEA 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1171 ITELADKLKTLEEKLQTLQSSHSKDRENYEKKI---------------EAFQQQETEVK---EL--VAQLDAYWKSA-EV 1229
Cdd:COG4913    403 LEEALAEAEAALRDLRRELRELEAEIASLERRKsniparllalrdalaEALGLDEAELPfvgELieVRPEEERWRGAiER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1230 LLQT-------------KSNELIEKCNEKIGIVTCKIADCERQATKVK-------EAVIIKMNKS----VQQLQEKDNVI 1285
Cdd:COG4913    483 VLGGfaltllvppehyaAALRWVNRLHLRGRLVYERVRTGLPDPERPRldpdslaGKLDFKPHPFrawlEAELGRRFDYV 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1286 KSmrDDIEGLVTEKEQLQKEG-GHQKQAATEKetcitQLRKELSE-------NINAVTSLREDLQEKESEISTLNKTINE 1357
Cdd:COG4913    563 CV--DSPEELRRHPRAITRAGqVKGNGTRHEK-----DDRRRIRSryvlgfdNRAKLAALEAELAELEEELAEAEERLEA 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1358 LNVRLESMvsltekeaaisllstqhqEERLQLINQVQELSSS---VELLRQEKASALEQVDHCTAKLSEWKTkAQTRFTQ 1434
Cdd:COG4913    636 LEAELDAL------------------QERREALQRLAEYSWDeidVASAEREIAELEAELERLDASSDDLAA-LEEQLEE 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1435 NHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQqgkdldsLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIA 1514
Cdd:COG4913    697 LEAELEELEEELDELKGEIGRLEKELEQAEEELDE-------LQDRLEAAEDLARLELRALLEERFAAALGDAVERELRE 769

                          570
                   ....*....|....*....
gi 2024469763 1515 QKTSENDSLKEELKRYHEQ 1533
Cdd:COG4913    770 NLEERIDALRARLNRAEEE 788
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
686-908 1.91e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 1.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  686 ETLSSELSEALKVRQDLEQELSELKSKVGEAkqefEGKLEAERNQHKEeveimlkeheISIQDVEKVLKEELNQMKQSLE 765
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEA----EAALEEFRQKNGL----------VDLSEEAKLLLQQLSELESQLA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  766 EKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQntSNEQAKQYEEELAKLQQK---LMDLKGEKLQLSEQL 842
Cdd:COG3206    230 EARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQ--LAELEAELAELSARYTPNhpdVIALRAQIAALRAQL 307

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763  843 -VRTECQLNEVKNELELYISQVHELKQQLQEQsdentQKAMSLTQQYESQLKDLQEEADKAKQTLTE 908
Cdd:COG3206    308 qQEAQRILASLEAELEALQAREASLQAQLAQL-----EARLAELPELEAELRRLEREVEVARELYES 369
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1055-1222 2.02e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 2.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1055 AEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKA 1134
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1135 QLQKLEGDLSQSLKE--KSGLQEQIS----------------RQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSK-- 1194
Cdd:COG4942     98 ELEAQKEELAELLRAlyRLGRQPPLAlllspedfldavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAERAEle 177

                          170       180
                   ....*....|....*....|....*....
gi 2024469763 1195 -DRENYEKKIEAFQQQETEVKELVAQLDA 1222
Cdd:COG4942    178 aLLAELEEERAALEALKAERQKLLARLEK 206
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1465-2084 2.19e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 2.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1465 EELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEEL--KRYHEQKDMEQKEVA 1542
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELngELSAADAAVAKDRSE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1543 WQLQQAEKVAFEKDsrlkEAEEKVLNLENEiGSLKAECEAKEREFDQMKSAILKSKEEELKELEERlNAENSCKLADLKK 1622
Cdd:pfam12128  324 LEALEDQHGAFLDA----DIETAAADQEQL-PSWQSELENLEERLKALTGKHQDVTAKYNRRRSKI-KEQNNRDIAGIKD 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1623 KAEqkigSIKRELVRQMEEKEQQLKQdRENQVRHlEQKVQEREAKIESLE-----EKMKSVRDSTELEREMLQKIESTKA 1697
Cdd:pfam12128  398 KLA----KIREARDRQLAVAEDDLQA-LESELRE-QLEAGKLEFNEEEYRlksrlGELKLRLNQATATPELLLQLENFDE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1698 AVEQEKNEviksvQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEkrhreeQSVTEGL 1777
Cdd:pfam12128  472 RIERAREE-----QEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQA------GTLLHFL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1778 REELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIMGDF----------QKKMQEKDAVSHSLE---QKV 1844
Cdd:pfam12128  541 RKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRidvpewaaseEELRERLDKAEEALQsarEKQ 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1845 KELEDNLAKVN---EVHKTEMEDRSLKYEENLKSLQQ-QLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQA 1920
Cdd:pfam12128  621 AAAEEQLVQANgelEKASREETFARTALKNARLDLRRlFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQA 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1921 KLEEAEREKqklrkdvnslqKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEdielKHSSTLKQLMREFNTQLAQKEM 2000
Cdd:pfam12128  701 WLEEQKEQK-----------REARTEKQAYWQVVEGALDAQLALLKAAIAARRS----GAKAELKALETWYKRDLASLGV 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2001 ELETAVKetisKAQEVESELIENHQIEttQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQ 2080
Cdd:pfam12128  766 DPDVIAK----LKREIRTLERKIERIA--VRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKL 839


                   ....
gi 2024469763 2081 RMAE 2084
Cdd:pfam12128  840 RRAK 843
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1026-1238 2.44e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 2.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1026 KEQLESLAEAHkRELEEISRswEKKLNQQAEELQEKHEmELQEKEQELGDLKEKLATFSAEkegsrTEITRLKEEQVKRN 1105
Cdd:COG4913    231 VEHFDDLERAH-EALEDARE--QIELLEPIRELAERYA-AARERLAELEYLRAALRLWFAQ-----RRLELLEAELEELR 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1106 ETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDlsqslkEKSGLQEQISRQkaieekdKARITELADKLKTLEEKL 1185
Cdd:COG4913    302 AELARLEAELERLEARLDALREELDELEAQIRGNGGD------RLEQLEREIERL-------ERELEERERRRARLEALL 368

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024469763 1186 QTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNEL 1238
Cdd:COG4913    369 AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRREL 421
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1870-2081 2.63e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1870 EENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKE 1949
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1950 HQQELD-IVKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELE--TAVKETISKAQEVESELIENHQI 2026
Cdd:COG4942    106 LAELLRaLYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAelAALRAELEAERAELEALLAELEE 185

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 2027 ETTQLHKKIAEKDDDLKRTVKKYeEILEAREEEMTTKVHELQTQLEELQKEYKQR 2081
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKEL-AELAAELAELQQEAEELEALIARLEAEAAAA 239
PRK12704 PRK12704
phosphodiesterase; Provisional
 1622-1806 4.63e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 51.70  E-value: 4.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1622 KKAEQKIGSIKRELVRQMEEKEQQLKQDrenqvrhLEQKVQEREAKIESLEEKMKsvrdstelEREmlQKIESTKAAVEQ 1701
Cdd:PRK12704    45 EEAKKEAEAIKKEALLEAKEEIHKLRNE-------FEKELRERRNELQKLEKRLL--------QKE--ENLDRKLELLEK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1702 EKNEVIKsvqqtHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQ--EELLKKLEcaEKRHREEQSVTEGLRE 1779
Cdd:PRK12704   108 REEELEK-----KEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEakEILLEKVE--EEARHEAAVLIKEIEE 180

                          170       180
                   ....*....|....*....|....*....
gi 2024469763 1780 ELEEQAKKYS--LLVDEHARCGGDLASSR 1806
Cdd:PRK12704   181 EAKEEADKKAkeILAQAIQRCAADHVAET 209
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
280-517 5.09e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  280 LETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQ------------EQLEERLQELEKMK---DLHMGEKTKLI 344
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeidvASAEREIAELEAELerlDASSDDLAALE 691

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  345 TQLRDAKNLIEQLEQDKGMVIAETKRqmhetlemKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQR 424
Cdd:COG4913    692 EQLEELEAELEELEEELDELKGEIGR--------LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAV 763

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  425 TEEARKKLQTEMDEKIKAVEKAnEEERVNLQQELTRVKQEVVEIMKKSSEDR---VAELEKLHKEEMATKDQELNERLQA 501
Cdd:COG4913    764 ERELRENLEERIDALRARLNRA-EEELERAMRAFNREWPAETADLDADLESLpeyLALLDRLEEDGLPEYEERFKELLNE 842

                          250
                   ....*....|....*.
gi 2024469763  502 QEREFQEKMKAALEKN 517
Cdd:COG4913    843 NSIEFVADLLSKLRRA 858
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 471-760 5.32e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 51.85  E-value: 5.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  471 KSSEDRVaeLEKLHKEEMA----TKDQELNERLQAQEREfQEKMKAALEKnqsecLKTLQEQEQQESLALEELELQK-KA 545
Cdd:PRK05771    15 KSYKDEV--LEALHELGVVhiedLKEELSNERLRKLRSL-LTKLSEALDK-----LRSYLPKLNPLREEKKKVSVKSlEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  546 IQSECDKKLEEMHQEVETFKTRILELESSLAKCsQDDKKRSEELSTL-MDSEKKQHNKEVSDIV-EKHKEELENVKQQQE 623
Cdd:PRK05771    87 LIKDVEEELEKIEKEIKELEEEISELENEIKEL-EQEIERLEPWGNFdLDLSLLLGFKYVSVFVgTVPEDKLEELKLESD 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  624 KLWTEKLQILQQQHVIEIEKMREkQEQEIDTILKEKEtvFRthieemNEKTLEKLDVKQtELETLSSELSEALKVRQDLE 703
Cdd:PRK05771   166 VENVEYISTDKGYVYVVVVVLKE-LSDEVEEELKKLG--FE------RLELEEEGTPSE-LIREIKEELEEIEKERESLL 235

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763  704 QELSELKSKVGEAKQEFEGKLEAERNqhKEEVEIMLK--EHEISIQ------DVEKvLKEELNQM 760
Cdd:PRK05771   236 EELKELAKKYLEELLALYEYLEIELE--RAEALSKFLktDKTFAIEgwvpedRVKK-LKELIDKA 297
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 134-709 5.46e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 5.46e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  134 EQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQSQDKALRRIGELREELQMDQQAKKHLQEEfDASLEE 213
Cdd:COG1196    249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL-EEELAE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  214 KDQLISVLQTQVSLLKQRLQNGQIGIElpdpnnQSEPQVQSQTKEINAENIVEPGSNEGNEDSVKTLETLNQRVKRQENL 293
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELE------EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  294 LQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDKGmVIAETKRQMH 373
Cdd:COG1196    402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE-EAALLEAALA 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  374 ETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEA-RKKLQTEMDEKIKAVEKANEEERV 452
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyEAALEAALAAALQNIVVEDDEVAA 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  453 NLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQE 532
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  533 SLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHK 612
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  613 EELENVKQQQEKLWTEKLQILQQQHVIEIEKM---------REKQEQEIDTILKEketvfrthIEEM---NEKTLEKLDV 680
Cdd:COG1196    721 LEEEALEEQLEAEREELLEELLEEEELLEEEAleelpeppdLEELERELERLERE--------IEALgpvNLLAIEEYEE 792

                          570       580
                   ....*....|....*....|....*....
gi 2024469763  681 KQTELETLSSElsealkvRQDLEQELSEL 709
Cdd:COG1196    793 LEERYDFLSEQ-------REDLEEARETL 814
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
274-792 5.88e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 5.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  274 EDSVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLE------ERLQELEKMKDLHMGEKTKLITQL 347
Cdd:PRK03918   182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKeleelkEEIEELEKELESLEGSKRKLEEKI 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  348 RDAKNLIEQLEqdKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAfEELEKALGMAQRTEE 427
Cdd:PRK03918   262 RELEERIEELK--KEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEI-NGIEERIKELEEKEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  428 ARKKLQTEMDEKIKAVEKAneEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKL------HKEEMATKDQELNERLQA 501
Cdd:PRK03918   339 RLEELKKKLKELEKRLEEL--EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKEleelekAKEEIEEEISKITARIGE 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  502 QEREFQEKMKA--ALEKNQSECLKTLQEQEQQESLALEELElqkKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCS 579
Cdd:PRK03918   417 LKKEIKELKKAieELKKAKGKCPVCGRELTEEHRKELLEEY---TAELKRIEKELKEIEEKERKLRKELRELEKVLKKES 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  580 QDDKKRseELSTLMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVI-EIEKMREKQEQEIDTILKE 658
Cdd:PRK03918   494 ELIKLK--ELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLeELKKKLAELEKKLDELEEE 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  659 KETVFRtHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIM 738
Cdd:PRK03918   572 LAELLK-ELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024469763  739 LKEHEISIQDVEKvLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAEL 792
Cdd:PRK03918   651 ELEKKYSEEEYEE-LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL 703
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1554-2044 6.62e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 6.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1554 EKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAEnscKLADLKKKAEQKIGSIKR 1633
Cdd:PRK03918   176 RRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE---ELKEEIEELEKELESLEG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1634 ElVRQMEEKEQQLKQDRENQVRHLEqKVQEREAKIESLEEKMKSVRDSTELEREM---LQKIESTKAAVEQEKNEVIKSV 1710
Cdd:PRK03918   253 S-KRKLEEKIRELEERIEELKKEIE-ELEEKVKELKELKEKAEEYIKLSEFYEEYldeLREIEKRLSRLEEEINGIEERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1711 QQThEEKINKLQKDLIEKNKLLQKYE--SEQREGIDSLLELQSKQEELLKKLECAEK-RHREEQSVTEGLREELEEQAKK 1787
Cdd:PRK03918   331 KEL-EEKEERLEELKKKLKELEKRLEelEERHELYEEAKAKKEELERLKKRLTGLTPeKLEKELEELEKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1788 YSLLVDEHARCGGDLASSREELKAKEQK---------NLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVH 1858
Cdd:PRK03918   410 ITARIGELKKEIKELKKAIEELKKAKGKcpvcgreltEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVL 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1859 KTEMEDRSLK-YEENLKSLQQQLEERNdrLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQaKLEEAEREKQKLRKDVN 1937
Cdd:PRK03918   490 KKESELIKLKeLAEQLKELEEKLKKYN--LEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLD 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1938 SLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVE 2017
Cdd:PRK03918   567 ELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELR 646

                          490       500
                   ....*....|....*....|....*..
gi 2024469763 2018 SELIENHQIETTQLHKKIAEKDDDLKR 2044
Cdd:PRK03918   647 KELEELEKKYSEEEYEELREEYLELSR 673
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1033-1237 6.79e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 6.79e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1033 AEAHKRELEEISRSWEKKLNQQAEELQEKHEM--ELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQ 1110
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALlkQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1111 LQEELKQSLAQM---------SALSNSESGLKAQ-----LQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELAD 1176
Cdd:COG4942    102 QKEELAELLRALyrlgrqpplALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024469763 1177 KLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNE 1237
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 923-1237 8.08e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 51.28  E-value: 8.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  923 EMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAK 1002
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMER 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1003 MLEMAHassagINDAVSKLESNQKEQLESLAEAHK-RELEEISRSWEKKLNQQAEELQEKHEMELQEKEQE--LGDLKEK 1079
Cdd:pfam17380  347 ERELER-----IRQEERKRELERIRQEEIAMEISRmRELERLQMERQQKNERVRQELEAARKVKILEEERQrkIQQQKVE 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1080 LATFSAEKEGSRT-EITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQ-- 1156
Cdd:pfam17380  422 MEQIRAEQEEARQrEVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKel 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1157 -ISRQKAIEEKDKARI--TELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQT 1233
Cdd:pfam17380  502 eERKQAMIEEERKRKLleKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQI 581


                   ....
gi 2024469763 1234 KSNE 1237
Cdd:pfam17380  582 VESE 585
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 582-1385 8.62e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.13  E-value: 8.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  582 DKKRSEELSTLM---------DSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEI 652
Cdd:pfam02463  168 KRKKKEALKKLIeetenlaelIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLR 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  653 DTILKEKETVFRTHIEEMNEKTLEKLDVK-------QTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLE 725
Cdd:pfam02463  248 DEQEEIESSKQEIEKEEEKLAQVLKENKEeekekklQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  726 AERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLS 805
Cdd:pfam02463  328 KELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEA 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  806 QQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLT 885
Cdd:pfam02463  408 QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  886 QQYESQLKDLQEEADKAKQTLTER-ENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKS- 963
Cdd:pfam02463  488 LLLSRQKLEERSQKESKARSGLKVlLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLv 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  964 KEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEI 1043
Cdd:pfam02463  568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1044 SRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMS 1123
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1124 ALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKaritELADKLKTLEEKLQTLQSSHSKDRENYEKKI 1203
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLK----EKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1204 EAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIgivtckiadceRQATKVKEAVIIKMNKSVQQLQEKDN 1283
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQ-----------KLEKLAEEELERLEEEITKEELLQEL 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1284 VIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLE 1363
Cdd:pfam02463  873 LLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEE 952

                          810       820
                   ....*....|....*....|..
gi 2024469763 1364 SMVSLTEKEAAISLLSTQHQEE 1385
Cdd:pfam02463  953 NNKEEEEERNKRLLLAKEELGK 974
PRK12704 PRK12704
phosphodiesterase; Provisional
 1019-1184 8.72e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 50.93  E-value: 8.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1019 SKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLatfsaekegsrteitRLK 1098
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRL---------------LQK 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1099 EEQV-KRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEE-KDKARiTELAD 1176
Cdd:PRK12704    95 EENLdRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAKEILLEKvEEEAR-HEAAV 173


                   ....*...
gi 2024469763 1177 KLKTLEEK 1184
Cdd:PRK12704   174 LIKEIEEE 181
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 886-1126 9.45e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 9.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  886 QQYESQLKDLQEEADKAKQTLTERENDIEHVKKvqneEMEELKQKLLATEERISTLqgdyENKLKRQENKMEKMKQKSKE 965
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLK----QLAALERRIAALARRIRAL----EQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  966 MQetfkKKLAEQESKLKKelenkQLEFSQKESEFNAKMLEMahaSSAGINDAVSKLESNQK--EQLESLAEAHKRELEEI 1043
Cdd:COG4942     95 LR----AELEAQKEELAE-----LLRALYRLGRQPPLALLL---SPEDFLDAVRRLQYLKYlaPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1044 SRSwEKKLNQQAEELQEKHEmELQEKEQELGDLKEK----LATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSL 1119
Cdd:COG4942    163 AAL-RAELEAERAELEALLA-ELEEERAALEALKAErqklLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                   ....*..
gi 2024469763 1120 AQMSALS 1126
Cdd:COG4942    241 ERTPAAG 247
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 897-1570 1.03e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.12  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  897 EEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENkLKRQENKMEKMKQKSKEMQETFKKKLAE 976
Cdd:TIGR00618  173 FPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQV-LEKELKHLREALQQTQQSHAYLTQKREA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  977 QESKLKKELENKQLEFSQKESEFNAKMLEMAH---------ASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSW 1047
Cdd:TIGR00618  252 QEEQLKKQQLLKQLRARIEELRAQEAVLEETQerinrarkaAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRA 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1048 EKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQ------VKRNETLKQLQEELKQSLAQ 1121
Cdd:TIGR00618  332 AHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQqqkttlTQKLQSLCKELDILQREQAT 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1122 MSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEK 1201
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAV 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1202 KIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNE-LIEKCNEKIGIVTCKIADCERQATKVKEAVII---KMNKSVQQ 1277
Cdd:TIGR00618  492 VLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASlkeQMQEIQQS 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1278 LQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINE 1357
Cdd:TIGR00618  572 FSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHAL 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1358 LnvrlesmVSLTEKEAAISLLSTQHQEERLQLINQVQElsSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHE 1437
Cdd:TIGR00618  652 Q-------LTLTQERVREHALSIRVLPKELLASRQLAL--QKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1438 ---TIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIA 1514
Cdd:TIGR00618  723 ienASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLK 802

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024469763 1515 QKTSEndsLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLE 1570
Cdd:TIGR00618  803 TLEAE---IGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYE 855
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1744-1970 1.17e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1744 DSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENIM 1823
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1824 GDFQKKMQEKDAVShsleQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLE 1903
Cdd:COG4942    100 EAQKEELAELLRAL----YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763 1904 LQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIR 1970
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 945-1541 1.36e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  945 YENKLKRQENKMEKMKQKSKEMQETFKKKLAE----QESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSK 1020
Cdd:TIGR04523   24 YKNIANKQDTEEKQLEKKLKTIKNELKNKEKElknlDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1021 LESNQKEQLESLAEAHKRELEEISRSweKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEE 1100
Cdd:TIGR04523  104 DLSKINSEIKNDKEQKNKLEVELNKL--EKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1101 QVKRNETLKQLQEELKQSLAQMSalsnsesglkaQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKT 1180
Cdd:TIGR04523  182 KLNIQKNIDKIKNKLLKLELLLS-----------NLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1181 LEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQA 1260
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQI 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1261 TKVKEAV------IIKMNKSVQ-----------QLQEKDNVIK-------SMRDDIEGLVTEKEQLQKEGGHQKQAATEK 1316
Cdd:TIGR04523  331 SQNNKIIsqlneqISQLKKELTnsesensekqrELEEKQNEIEklkkenqSYKQEIKNLESQINDLESKIQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1317 ETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEK-EAAISLLSTQHQEERLQLINQVQE 1395
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESlETQLKVLSRSINKIKQNLEQKQKE 490

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1396 LSSSV---ELLRQEKASALEQVDHCTAKLSEWKTKAQ---TRFTQNHETIKDLQSKLEVSNTQATKKG--EELDKLKEEL 1467
Cdd:TIGR04523  491 LKSKEkelKKLNEEKKELEEKVKDLTKKISSLKEKIEkleSEKKEKESKISDLEDELNKDDFELKKENleKEIDEKNKEI 570

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763 1468 AQQGKDLDSLKSVLEEKENRIEKQESE---LTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEV 1541
Cdd:TIGR04523  571 EELKQTQKSLKKKQEEKQELIDQKEKEkkdLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEV 647
46 PHA02562
endonuclease subunit; Provisional
 1834-2039 1.50e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.01  E-value: 1.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1834 DAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENL---KSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGD 1910
Cdd:PHA02562   187 DMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVeeaKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAK 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1911 MQNQQKDLQaKLEEAERE-------KQKLRKDVNSLQKdLRTLRKEHQQELDIVKK--ESLEEMEQKIRCEQEDI-ELKH 1980
Cdd:PHA02562   267 IKSKIEQFQ-KVIKMYEKggvcptcTQQISEGPDRITK-IKDKLKELQHSLEKLDTaiDELEEIMDEFNEQSKKLlELKN 344

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1981 S-STLKQLMREFNTQLAQKEMELETAVKETISKAQEVEsELIENHQIETTQLHKKIAEKD 2039
Cdd:PHA02562   345 KiSTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELA-KLQDELDKIVKTKSELVKEKY 403
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1373-1586 1.59e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1373 AAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEwktkAQTRFTQNHETIKDLQSKLEVSNTQ 1452
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAA----LARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1453 ATKKGEELDKLKEELAQQGKDL------DSLKSVLEEKE-----------NRIEKQESELTAELKIQAARVAELEEHIAQ 1515
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALyrlgrqPPLALLLSPEDfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024469763 1516 KTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKERE 1586
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1870-2136 1.62e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1870 EENLKSLQQQLEERNDRLKALEENAEeKAKSGLELQKLLGDMQNQQ-----KDLQAKLEEAEREKQKLRKDVNSLQKDLR 1944
Cdd:COG1196    185 EENLERLEDILGELERQLEPLERQAE-KAERYRELKEELKELEAELlllklRELEAELEELEAELEELEAELEELEAELA 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1945 TLRKEHQQEldivkKESLEEMEQKIRCEQEDIELKHSSTLK-----QLMREFNTQLAQKEMELETAVKETISKAQEVESE 2019
Cdd:COG1196    264 ELEAELEEL-----RLELEELELELEEAQAEEYELLAELARleqdiARLEERRRELEERLEELEEELAELEEELEELEEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2020 LIENhQIETTQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSENVTIAELQ 2099
Cdd:COG1196    339 LEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE 417

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 2024469763 2100 AQLAQKTTLVNDSKLKEQEFKEQIHVLEDRLKNYEKK 2136
Cdd:COG1196    418 RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1388-1953 2.71e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1388 QLINQVQELSSSVELLR--QEKASALEQ-VDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLK 1464
Cdd:COG4913    229 ALVEHFDDLERAHEALEdaREQIELLEPiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1465 EELAQQGKDLDSLKSVLEE-----------KENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQ 1533
Cdd:COG4913    309 AELERLEARLDALREELDEleaqirgnggdRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1534 KDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKaeceakerefdQMKSAILKSKEEELKELEERLNAEN 1613
Cdd:COG4913    389 AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE-----------RRKSNIPARLLALRDALAEALGLDE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1614 S-----CKLADLKKKAEQKIGSIKREL--------VRqmEEKEQQLKQ--DREN--------QVRHLEQKVQEREAKIES 1670
Cdd:COG4913    458 AelpfvGELIEVRPEEERWRGAIERVLggfaltllVP--PEHYAAALRwvNRLHlrgrlvyeRVRTGLPDPERPRLDPDS 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1671 LEEKMkSVRDST---ELEREMLQKIESTKAAVEQEKNEVIKSVQQTheekinklqkDLIEKNKllQKYESEQREGIDSLL 1747
Cdd:COG4913    536 LAGKL-DFKPHPfraWLEAELGRRFDYVCVDSPEELRRHPRAITRA----------GQVKGNG--TRHEKDDRRRIRSRY 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1748 EL----QSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLL--VDEHARCGGDLASSREELKAKEQKNLGMEN 1821
Cdd:COG4913    603 VLgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALqrLAEYSWDEIDVASAEREIAELEAELERLDA 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1822 IMGDFQKkmqekdavshsLEQKVKELEDNLAKVNEvHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSG 1901
Cdd:COG4913    683 SSDDLAA-----------LEEQLEELEAELEELEE-ELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024469763 1902 LELQKLLGDMQNQQKDLQAKLEEaerEKQKLRKDVNSLQKDLRTLRKEHQQE 1953
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEE---RIDALRARLNRAEEELERAMRAFNRE 799
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2163-2202 3.30e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 42.73  E-value: 3.30e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2024469763 2163 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPADQTQKI 2202
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1276-1756 3.52e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1276 QQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKEtcITQLRKELSENINAVTSLREDLQEKESEISTLNKTI 1355
Cdd:COG4913    255 EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAE--LEELRAELARLEAELERLEARLDALREELDELEAQI 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1356 NELNV----RLESMVSLTEKEAAisllstQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTR 1431
Cdd:COG4913    333 RGNGGdrleQLEREIERLERELE------ERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEA 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1432 FTQNHETIKDLQSKL-----EVSNTQATKK--GEELDKLKEELAQQ-GKDLDSLKSVLE-----EKENR----IEK---- 1490
Cdd:COG4913    407 LAEAEAALRDLRRELreleaEIASLERRKSniPARLLALRDALAEAlGLDEAELPFVGElievrPEEERwrgaIERvlgg 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1491 ----------QESELTA-------ELKIQAARVAELEEHIAQKTSENDSLKEELK-RYHEQKDMEQKEVAW--------- 1543
Cdd:COG4913    487 faltllvppeHYAAALRwvnrlhlRGRLVYERVRTGLPDPERPRLDPDSLAGKLDfKPHPFRAWLEAELGRrfdyvcvds 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1544 --QLQQAEK------------VAFEKDSRLKEAEEKVLNLENE--IGSLKAECEAKEREFDQMKSAILKSKEEELKELEE 1607
Cdd:COG4913    567 peELRRHPRaitragqvkgngTRHEKDDRRRIRSRYVLGFDNRakLAALEAELAELEEELAEAEERLEALEAELDALQER 646

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1608 RLNAENSCKLADLKKK---AEQKIGSIKREL---------VRQMEEKEQQLKQDRENqvrhLEQKVQEREAKIESLEEKM 1675
Cdd:COG4913    647 REALQRLAEYSWDEIDvasAEREIAELEAELerldassddLAALEEQLEELEAELEE----LEEELDELKGEIGRLEKEL 722

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1676 KSVRDSTELEREMLQKIESTKA-----------------AVEQEKNEVIKSVQQTHEEKINKLQKDLIEK-NKLLQKYES 1737
Cdd:COG4913    723 EQAEEELDELQDRLEAAEDLARlelralleerfaaalgdAVERELRENLEERIDALRARLNRAEEELERAmRAFNREWPA 802

                          570
                   ....*....|....*....
gi 2024469763 1738 EQREGIDSLLELQSKQEEL 1756
Cdd:COG4913    803 ETADLDADLESLPEYLALL 821
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1325-1899 5.01e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.74  E-value: 5.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1325 KELSENINAVTSLREDLQEKESEISTLNKTINElnvrLESMVSLTEKEaaISLLSTQHQEERLQLINQVQELsssvellr 1404
Cdd:PRK01156   176 DMLRAEISNIDYLEEKLKSSNLELENIKKQIAD----DEKSHSITLKE--IERLSIEYNNAMDDYNNLKSAL-------- 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1405 QEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELD---KLKEELAQQGKDLDSLK--- 1478
Cdd:PRK01156   242 NELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINdyfKYKNDIENKKQILSNIDaei 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1479 ----------SVLEEKENRIEKQESELTaELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQA 1548
Cdd:PRK01156   322 nkyhaiikklSVLQKDYNDYIKKKSRYD-DLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQ 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1549 EKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKskeeelkeleerLNAENSCKLADLKKKAEQki 1628
Cdd:PRK01156   401 EIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEM------------LNGQSVCPVCGTTLGEEK-- 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1629 gsiKRELVRQMEEKEQQLkqdrENQVRHLEQKVQEREAKIESLeEKMKSVRDSTELEREM--LQKIESTKAAVEQEKNEV 1706
Cdd:PRK01156   467 ---SNHIINHYNEKKSRL----EEKIREIEIEVKDIDEKIVDL-KKRKEYLESEEINKSIneYNKIESARADLEDIKIKI 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1707 --IKSVQQTHEEKINKLQKDLIEknKLLQKYES-----EQREGIDsLLELQSKQEELLKKLECAEKRHREEQSVTEGLRE 1779
Cdd:PRK01156   539 neLKDKHDKYEEIKNRYKSLKLE--DLDSKRTSwlnalAVISLID-IETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKS 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1780 ELEEQAKKysllVDEHARcggDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQ---KVKELEDNLAKVNE 1856
Cdd:PRK01156   616 YIDKSIRE----IENEAN---NLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEitsRINDIEDNLKKSRK 688

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 2024469763 1857 VHKTEMEDRSlKYEENLKSLQQQLEERNDRLKALEENAEEKAK 1899
Cdd:PRK01156   689 ALDDAKANRA-RLESTIEILRTRINELSDRINDINETLESMKK 730
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1616-1796 6.05e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 6.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1616 KLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRD---------STELER 1686
Cdd:PRK05771    57 EALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQeierlepwgNFDLDL 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1687 EMLQKIESTKAAV----EQEKNEVIKSVQQTHEEKINK-----------LQKDLIEKNKLLQKYE------------SEQ 1739
Cdd:PRK05771   137 SLLLGFKYVSVFVgtvpEDKLEELKLESDVENVEYISTdkgyvyvvvvvLKELSDEVEEELKKLGferleleeegtpSEL 216

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763 1740 REGIDS-LLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYS-LLVDEHA 1796
Cdd:PRK05771   217 IREIKEeLEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEALSkFLKTDKT 275
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 794-987 6.26e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 48.10  E-value: 6.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  794 QVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLqeq 873
Cdd:pfam05667  310 NEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQY--- 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  874 sdENTQKAMSLTQQYESQLKDLQEEADKAKQTLTEREndiehvkkvqnEEMEELKQKLLATEERISTLQGDYENKLKRQE 953
Cdd:pfam05667  387 --KVKKKTLDLLPDAEENIAKLQALVDASAQRLVELA-----------GQWEKHRVPLIEEYRALKEAKSNKEDESQRKL 453

                          170       180       190
                   ....*....|....*....|....*....|....
gi 2024469763  954 NKMEKMKQKSKEMQETFKKKlAEQESKLKKELEN 987
Cdd:pfam05667  454 EEIKELREKIKEVAEEAKQK-EELYKQLVAEYER 486
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1051-1375 6.51e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.59  E-value: 6.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1051 LNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSES 1130
Cdd:COG4372     25 LIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1131 GLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQE 1210
Cdd:COG4372    105 SLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1211 TEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKSMRD 1290
Cdd:COG4372    185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1291 DIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTE 1370
Cdd:COG4372    265 LAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQ 344


                   ....*
gi 2024469763 1371 KEAAI 1375
Cdd:COG4372    345 LLLVG 349
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1069-1731 9.88e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.71  E-value: 9.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1069 KEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLK 1148
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1149 E-------KSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHS---KDRENYEKKIEAFQQQETEVKELVA 1218
Cdd:TIGR04523  111 EikndkeqKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNdlkKQKEELENELNLLEKEKLNIQKNID 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1219 QLDAYWKSAEVLLQTksnelIEKCNEKIGIVTCKIADCERQATKVKEAVIIK---MNKSVQQLQEKDNVIKSMRDDIEGL 1295
Cdd:TIGR04523  191 KIKNKLLKLELLLSN-----LKKKIQKNKSLESQISELKKQNNQLKDNIEKKqqeINEKTTEISNTQTQLNQLKDEQNKI 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1296 VTEKEQLQKEGGHQKQAATEKETCITQLRKELSE-----NINAVTSLREDLQEKESEISTLNKTINELNvrlESMVSLTE 1370
Cdd:TIGR04523  266 KKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDlnnqkEQDWNKELKSELKNQEKKLEEIQNQISQNN---KIISQLNE 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1371 KEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEWKTKAQtrftQNHETIKDLQSKLEVSN 1450
Cdd:TIGR04523  343 QISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQ----NQEKLNQQKDEQIKKLQ 418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1451 TQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESeltaelkiqaarvaeLEEHIAQKTSENDSLKEELKRY 1530
Cdd:TIGR04523  419 QEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDN---------------TRESLETQLKVLSRSINKIKQN 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1531 HEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAIlkskeeelKELEERLN 1610
Cdd:TIGR04523  484 LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDEL--------NKDDFELK 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1611 AENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQdRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQ 1690
Cdd:TIGR04523  556 KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ-KEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIK 634

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 2024469763 1691 KIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKL 1731
Cdd:TIGR04523  635 NIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKI 675
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1053-1205 1.09e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.07  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1053 QQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQ--SLAQMSALSNSES 1130
Cdd:COG1579     20 DRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIE 99

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1131 GLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEA 1205
Cdd:COG1579    100 SLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 777-1529 1.20e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  777 REQELKESAQRSEAELVQVSA---RLMEASLSQQntsnEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVK 853
Cdd:COG3096    313 RELEELSARESDLEQDYQAASdhlNLVQTALRQQ----EKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAE 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  854 NELELYISQVHELKQQLQEQSD------------ENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEH------ 915
Cdd:COG3096    389 EEVDSLKSQLADYQQALDVQQTraiqyqqavqalEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQklsvad 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  916 VKKVQNEEMEELKQKLLATEERistlqgdyenklkrqenkmEKMKQKSKEMQETFK--KKLAEQESKLKKEL-ENKQLEF 992
Cdd:COG3096    469 AARRQFEKAYELVCKIAGEVER-------------------SQAWQTARELLRRYRsqQALAQRLQQLRAQLaELEQRLR 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  993 SQKESEfnakmlemahassagindavsklesnqkEQLESLAEAHKRELEEisrswekklNQQAEELQEKHEMELQEKEQE 1072
Cdd:COG3096    530 QQQNAE----------------------------RLLEEFCQRIGQQLDA---------AEELEELLAELEAQLEELEEQ 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1073 LGDLKEKLATFSAEKEGSRTEITRLKE---EQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKE 1149
Cdd:COG3096    573 AAEAVEQRSELRQQLEQLRARIKELAArapAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAAR 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1150 KSGLQEQISRQKAIEEKDKARITELADK------------------------------------LKTLEEKLQTLQSSHS 1193
Cdd:COG3096    653 KQALESQIERLSQPGGAEDPRLLALAERlggvllseiyddvtledapyfsalygparhaivvpdLSAVKEQLAGLEDCPE 732

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1194 kDRENYEKKIEAFQQQETEVKEL----VAQL-DAYW-------------KSAEVLLQTKSNELiEKCNEKIGIVTCKIAD 1255
Cdd:COG3096    733 -DLYLIEGDPDSFDDSVFDAEELedavVVKLsDRQWrysrfpevplfgrAAREKRLEELRAER-DELAEQYAKASFDVQK 810

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1256 CERQATKVKEavIIKMNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRK---------- 1325
Cdd:COG3096    811 LQRLHQAFSQ--FVGGHLAVAFAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKllpqanllad 888

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1326 -ELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELS------- 1397
Cdd:COG3096    889 eTLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSevvqrrp 968

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1398 -----SSVELLrqEKASAL-----EQVDHCTAKLSEWKTK---AQTRFTQNHETIKDLQSKLEVsntqatkKGEELDKLK 1464
Cdd:COG3096    969 hfsyeDAVGLL--GENSDLneklrARLEQAEEARREAREQlrqAQAQYSQYNQVLASLKSSRDA-------KQQTLQELE 1039

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1465 EELAQQGKDLDSlksvleEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKR 1529
Cdd:COG3096   1040 QELEELGVQADA------EAEERARIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRK 1098
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 805-1370 1.38e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  805 SQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDE--NTQKAM 882
Cdd:TIGR04523  110 SEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEklNIQKNI 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  883 SLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQN---EEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKM 959
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNqlkDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  960 KQKSKEMQETfKKKLAEQESKLKkelenkqlefsqkesEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLaEAHKRE 1039
Cdd:TIGR04523  270 SEKQKELEQN-NKKIKELEKQLN---------------QLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEI-QNQISQ 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1040 LEEISRSWEKKLNQQAEELQEKhEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSL 1119
Cdd:TIGR04523  333 NNKIISQLNEQISQLKKELTNS-ESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKD 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1120 AQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENY 1199
Cdd:TIGR04523  412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1200 EKKIEAFQQQETEVKELVAQLDAYWKSaevllQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAviIKMNKSVQQLQ 1279
Cdd:TIGR04523  492 KSKEKELKKLNEEKKELEEKVKDLTKK-----ISSLKEKIEKLESEKKEKESKISDLEDELNKDDFE--LKKENLEKEID 564

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1280 EKDNVIKSMRDDIEGLVTEKEQLQKEgghqkqaATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELN 1359
Cdd:TIGR04523  565 EKNKEIEELKQTQKSLKKKQEEKQEL-------IDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIK 637

                          570
                   ....*....|.
gi 2024469763 1360 VRLESMVSLTE 1370
Cdd:TIGR04523  638 SKKNKLKQEVK 648
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1282-1525 1.56e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.36  E-value: 1.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1282 DNVIKSMRDDIEGLVTEKEQLQKEgghqkqaateketcITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVR 1361
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAE--------------LDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1362 LESMVSLTEKEAAisllSTQHQEERLQLINQVQELSSSVELLRQekASALEQVdhctaklsewkTKAQTRFTqnhETIKD 1441
Cdd:COG3883     81 IEERREELGERAR----ALYRSGGSVSYLDVLLGSESFSDFLDR--LSALSKI-----------ADADADLL---EELKA 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1442 LQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSEND 1521
Cdd:COG3883    141 DKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220


                   ....
gi 2024469763 1522 SLKE 1525
Cdd:COG3883    221 AAAA 224
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 495-1123 1.57e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 1.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  495 LNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQ---ESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILEL 571
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEitgLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  572 ESSLAKcsqddkkrseelstlMDSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEiekmREKQEQE 651
Cdd:pfam15921  323 ESTVSQ---------------LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLD----DQLQKLL 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  652 IDTILKEKETVFRthiEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSkvgEAKQEFEGKLEA--ERN 729
Cdd:pfam15921  384 ADLHKREKELSLE---KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS---ECQGQMERQMAAiqGKN 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  730 QHKEEVEIMLKEHEISIQDVEKVLkEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNT 809
Cdd:pfam15921  458 ESLEKVSSLTAQLESTKEMLRKVV-EELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  810 SNE----QAKQYEEELAKLQ----QKLMDLKGEKLQLSEQLV----RTECQLNEVKNELELYISQVHELKQQLQEQSDEN 877
Cdd:pfam15921  537 KNEgdhlRNVQTECEALKLQmaekDKVIEILRQQIENMTQLVgqhgRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKK 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  878 TQKAMSLtqqyESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQkllaTEERISTLQGDYEnKLKRQenkme 957
Cdd:pfam15921  617 DAKIREL----EARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKT----SRNELNSLSEDYE-VLKRN----- 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  958 kMKQKSKEMQETfkkklaeqESKLKKELENKQLEFSQKESEFnaKMLEMAHASSAGINDAVSKLESNQKEQLESLaEAHK 1037
Cdd:pfam15921  683 -FRNKSEEMETT--------TNKLKMQLKSAQSELEQTRNTL--KSMEGSDGHAMKVAMGMQKQITAKRGQIDAL-QSKI 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1038 RELEEISRSWEKklnqqaeelqEKHEMelqekEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQ 1117
Cdd:pfam15921  751 QFLEEAMTNANK----------EKHFL-----KEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK 815


                   ....*.
gi 2024469763 1118 SLAQMS 1123
Cdd:pfam15921  816 ASLQFA 821
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 310-1140 1.57e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.35  E-value: 1.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  310 QLTNEKEALQEQLEERLQELEKMKDLHM---GEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHE-------TLEMK 379
Cdd:TIGR00606  238 EIVKSYENELDPLKNRLKEIEHNLSKIMkldNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDlyhnhqrTVREK 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  380 EEEVAQLRARIKQITTQGEELKEQKEKFEraafEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKANEEERVNLQQELT 459
Cdd:TIGR00606  318 ERELVDCQRELEKLNKERRLLNQEKTELL----VEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIK 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  460 RVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQ--ELNERLQAQEREFQEKmKAALEKNQSECLKTLQEQEQQESLALE 537
Cdd:TIGR00606  394 NFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQadEIRDEKKGLGRTIELK-KEILEKKQEELKFVIKELQQLEGSSDR 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  538 ELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTL------------MDSEKKQHNKEVS 605
Cdd:TIGR00606  473 ILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLnhhtttrtqmemLTKDKMDKDEQIR 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  606 DIVEKHKEELenVKQQQEKLWTEKLQILQQQHVIEIEKMREKQeQEIDTILKEKETVFRTHIEEMNEKTLEKLDVK---- 681
Cdd:TIGR00606  553 KIKSRHSDEL--TSLLGYFPNKKQLEDWLHSKSKEINQTRDRL-AKLNKELASLEQNKNHINNELESKEEQLSSYEdklf 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  682 --------QTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEG---------KLEAERNQHKEEVEIMLKEHEI 744
Cdd:TIGR00606  630 dvcgsqdeESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSccpvcqrvfQTEAELQEFISDLQSKLRLAPD 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  745 SIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESaqRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKL 824
Cdd:TIGR00606  710 KLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPEL--RNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVC 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  825 QQKLMDLKGEKLQLSEQLVRTECQLNEVKN-ELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAK 903
Cdd:TIGR00606  788 LTDVTIMERFQMELKDVERKIAQQAAKLQGsDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTN 867

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  904 QTLTERENDIEHVKKVQneEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEM---QETFKKKLAEQESK 980
Cdd:TIGR00606  868 ELKSEKLQIGTNLQRRQ--QFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELissKETSNKKAQDKVND 945

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  981 LKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKeqleslaeaHKRELEEISRSWEKKLN-QQAEELQ 1059
Cdd:TIGR00606  946 IKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEK---------HQEKINEDMRLMRQDIDtQKIQERW 1016

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1060 EKHEMELQEKEQELGDLKEKLATFsaEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKL 1139
Cdd:TIGR00606 1017 LQDNLTLRKRENELKEVEEELKQH--LKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREP 1094


                   .
gi 2024469763 1140 E 1140
Cdd:TIGR00606 1095 Q 1095
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 571-1110 1.97e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 46.64  E-value: 1.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  571 LESSLAKCSQDDKKRSEELSTLMDSEKKQHN--KEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQ 648
Cdd:pfam05483  263 LEESRDKANQLEEKTKLQDENLKELIEKKDHltKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNK 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  649 EQ--------EIDTILKEKETVFRTHIEEMnEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEF 720
Cdd:pfam05483  343 AKaahsfvvtEFEATTCSLEELLRTEQQRL-EKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLL 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  721 egkleaERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLM 800
Cdd:pfam05483  422 ------DEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCD 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  801 EASLSQQNTSNEqAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQK 880
Cdd:pfam05483  496 KLLLENKELTQE-ASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEEN 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  881 AMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQnEEMEELKQKLLATEERISTlqgdYENKLKRQENKMEKMK 960
Cdd:pfam05483  575 ARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELH-QENKALKKKGSAENKQLNA----YEIKVNKLELELASAK 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  961 QKSKEMQETFKKklaeqESKLKKELENKQLEFSQKEsefnakmlEMAHASSAGINDAVSKLESNQKEQLESLAEAHKREL 1040
Cdd:pfam05483  650 QKFEEIIDNYQK-----EIEDKKISEEKLLEEVEKA--------KAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQY 716

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1041 EEISRSWEKKLNQQAEELQEKHEMELQeKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQ 1110
Cdd:pfam05483  717 DKIIEERDSELGLYKNKEQEQSSAKAA-LEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
46 PHA02562
endonuclease subunit; Provisional
 1325-1536 2.09e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.55  E-value: 2.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1325 KELSENINAVTSLREDLQEKeseISTLNKTINELN-------VRLESMV-SLTEKEAAISLLSTQHQEERLQLINQVQEL 1396
Cdd:PHA02562   177 RELNQQIQTLDMKIDHIQQQ---IKTYNKNIEEQRkkngeniARKQNKYdELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1397 SSSVELLRQEKASALEQVDHCTaKLSEWKTKAQT-------------RFTQNHETIKDLQSKLEvsntQATKKGEELDKL 1463
Cdd:PHA02562   254 SAALNKLNTAAAKIKSKIEQFQ-KVIKMYEKGGVcptctqqisegpdRITKIKDKLKELQHSLE----KLDTAIDELEEI 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1464 KEELAQQGKDLDSLKSVLE----------EKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQ 1533
Cdd:PHA02562   329 MDEFNEQSKKLLELKNKIStnkqslitlvDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIV 408


                   ...
gi 2024469763 1534 KDM 1536
Cdd:PHA02562   409 TDL 411
mukB PRK04863
chromosome partition protein MukB;
134-500 2.21e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.87  E-value: 2.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  134 EQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQS----QDKALRRIGELREELQMDQQAKKHLQeEFDA 209
Cdd:PRK04863   840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllaDETLADRVEEIREQLDEAEEAKRFVQ-QHGN 918

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  210 SLEEKDQLISVLQT---QVSLLKQRLQNGQigielpdpnnqsepqvqsqtkeinaenivepgsnegnedsvKTLETLNQR 286
Cdd:PRK04863   919 ALAQLEPIVSVLQSdpeQFEQLKQDYQQAQ-----------------------------------------QTQRDAKQQ 957

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  287 VKRQENLLQRckemiRSH--KERCAQLTNEKEALQEQLEERLQELEKMKDlhmgektKLITQLRDAKNLIEQLEQdkgmV 364
Cdd:PRK04863   958 AFALTEVVQR-----RAHfsYEDAAEMLAKNSDLNEKLRQRLEQAEQERT-------RAREQLRQAQAQLAQYNQ----V 1021

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  365 IAETKrqmhETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERaafEELEKALGMAQ-RTEEARKKLQT---EMDEKI 440
Cdd:PRK04863  1022 LASLK----SSYDAKRQMLQELKQELQDLGVPADSGAEERARARR---DELHARLSANRsRRNQLEKQLTFceaEMDNLT 1094

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024469763  441 KAVEKAnEEERVNLQQELTRVKQEVVEIMKKSSEDRVaeLEKLHKEEMA-TKDQELNERLQ 500
Cdd:PRK04863  1095 KKLRKL-ERDYHEMREQVVNAKAGWCAVLRLVKDNGV--ERRLHRRELAyLSADELRSMSD 1152
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 134-387 2.31e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.48  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  134 EQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQ----SQDKALRRIGELREELQMDQQAKKHLQEeFDA 209
Cdd:COG3096    839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQanllADETLADRLEELREELDAAQEAQAFIQQ-HGK 917

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  210 SLEEKDQLISVLQT---QVSLLKQRLQngqigielpdpnnQSEPQVQSQTKEINA-ENIVEPGSNEGNEDSVKTL----- 280
Cdd:COG3096    918 ALAQLEPLVAVLQSdpeQFEQLQADYL-------------QAKEQQRRLKQQIFAlSEVVQRRPHFSYEDAVGLLgensd 984

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  281 --ETLNQRVKRQENLLQRCKEMIRSHKERCAQ-------LTNEKEALQEQLEERLQELEKM--------KDLHMGEKTKL 343
Cdd:COG3096    985 lnEKLRARLEQAEEARREAREQLRQAQAQYSQynqvlasLKSSRDAKQQTLQELEQELEELgvqadaeaEERARIRRDEL 1064

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 2024469763  344 ITQLRDAKNLIEQLEQDKGMVIAETKrQMHETLEMKEEEVAQLR 387
Cdd:COG3096   1065 HEELSQNRSRRSQLEKQLTRCEAEMD-SLQKRLRKAERDYKQER 1107
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 921-1135 2.36e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 2.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  921 NEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETfKKKLAEQESKLKKELEnkqlefSQKESEFN 1000
Cdd:COG3883     29 QAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEA-EAEIEERREELGERAR------ALYRSGGS 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1001 AKMLEMAhASSAGINDAVSKLESnqkeqLESLAEAHKRELEEISRSwEKKLNQQAEELQEKHEmELQEKEQELGDLKEKL 1080
Cdd:COG3883    102 VSYLDVL-LGSESFSDFLDRLSA-----LSKIADADADLLEELKAD-KAELEAKKAELEAKLA-ELEALKAELEAAKAEL 173

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1081 ATFSAEKEGsrtEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQ 1135
Cdd:COG3883    174 EAQQAEQEA---LLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
922-1117 2.45e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  922 EEMEELKQKLlATEERISTLQGDYEnKLKRQENKMEKMKQKSK-EMQETFKKKLAEQESKLKKELENKQLEFSQKESEFN 1000
Cdd:COG4913    242 EALEDAREQI-ELLEPIRELAERYA-AARERLAELEYLRAALRlWFAQRRLELLEAELEELRAELARLEAELERLEARLD 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1001 AkmlemAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEkKLNQQAEELQEKHEMELQEKEQELGDLKEKL 1080
Cdd:COG4913    320 A-----LREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRA-RLEALLAALGLPLPASAEEFAALRAEAAALL 393

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2024469763 1081 ATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQ 1117
Cdd:COG4913    394 EALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 481-734 2.49e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.27  E-value: 2.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  481 EKLHKEEMATKDQELNERLQAQERefQEKMKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQ- 559
Cdd:pfam17380  291 EKFEKMEQERLRQEKEEKAREVER--RRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQe 368

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  560 EVETFKTRILELESSLAKCSQDDKKRSEELSTLmdSEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVI 639
Cdd:pfam17380  369 EIAMEISRMRELERLQMERQQKNERVRQELEAA--RKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAR 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  640 EIEKMREKQ---------------EQEIDTILKEKETVFRTHIEEMNEKTLEKldvkqtELETLSSELSEALKVRQDLEQ 704
Cdd:pfam17380  447 EMERVRLEEqerqqqverlrqqeeERKRKKLELEKEKRDRKRAEEQRRKILEK------ELEERKQAMIEEERKRKLLEK 520

                          250       260       270
                   ....*....|....*....|....*....|
gi 2024469763  705 ELSELKSKVGEAKQEFEGKLEAERNQHKEE 734
Cdd:pfam17380  521 EMEERQKAIYEEERRREAEEERRKQQEMEE 550
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
789-1120 2.77e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 45.66  E-value: 2.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  789 EAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQ 868
Cdd:COG4372     22 TGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  869 QLQEQSDENTQKAMSLtQQYESQLKDLQEEADKAKQTLTERENDIEHvkkvQNEEMEELKQKLLATEERISTLQGDYENK 948
Cdd:COG4372    102 ELESLQEEAEELQEEL-EELQKERQDLEQQRKQLEAQIAELQSEIAE----REEELKELEEQLESLQEELAALEQELQAL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  949 LKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQ 1028
Cdd:COG4372    177 SEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVI 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1029 LESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETL 1108
Cdd:COG4372    257 LKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILL 336

                          330
                   ....*....|..
gi 2024469763 1109 KQLQEELKQSLA 1120
Cdd:COG4372    337 AELADLLQLLLV 348
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1007-1218 3.24e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1007 AHASSAGINDAVSKLESNQKE------QLESLAEAHKRELEEISRSwEKKLNQQAEELQEkHEMELQEKEQELGDLKEKL 1080
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEiaelekELAALKKEEKALLKQLAAL-ERRIAALARRIRA-LEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1081 ATFSAEKEGSRTEITRL---------------------KEEQVKRNETLKQLQEELKQSLAQMSALsnsesglKAQLQKL 1139
Cdd:COG4942     93 AELRAELEAQKEELAELlralyrlgrqpplalllspedFLDAVRRLQYLKYLAPARREQAEELRAD-------LAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763 1140 EGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVA 1218
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
COG5022 COG5022
Myosin heavy chain [General function prediction only];
944-1213 3.39e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 46.22  E-value: 3.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  944 DYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKEsefnAKMLEMAHASSAGINDAVSKLE- 1022
Cdd:COG5022    821 KLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQS----AQRVELAERQLQELKIDVKSISs 896

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1023 -SNQKEQLESLAEAHKREL------------EEISRSWEKKLNQQAEELQEKhEMELQEKEQELGDLKEKLATFSAEKEG 1089
Cdd:COG5022    897 lKLVNLELESEIIELKKSLssdlienlefktELIARLKKLLNNIDLEEGPSI-EYVKLPELNKLHEVESKLKETSEEYED 975

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1090 SRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLK---AQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEK 1166
Cdd:COG5022    976 LLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKelpVEVAELQSASKIISSESTELSILKPLQKLKGLL 1055

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024469763 1167 DKArITELADKLKTLE-----EKLQTLQSSHSKDRENYEKKIEAFQQQETEV 1213
Cdd:COG5022   1056 LLE-NNQLQARYKALKlrrenSLLDDKQLYQLESTENLLKTINVKDLEVTNR 1106
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1437-1700 3.40e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 45.69  E-value: 3.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1437 ETIKDLQ--SKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEE----KENRIEKQESELTAELKIQAARVAELE 1510
Cdd:PRK05771    20 EVLEALHelGVVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKlnplREEKKKVSVKSLEELIKDVEEELEKIE 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1511 EHIAQKTSENDSLKEELKRYHEQKD----MEQKEVAWQLQQAEKVAFEKDSRLKeaEEKVLNLENEIGSLKAECEAKERE 1586
Cdd:PRK05771   100 KEIKELEEEISELENEIKELEQEIErlepWGNFDLDLSLLLGFKYVSVFVGTVP--EDKLEELKLESDVENVEYISTDKG 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1587 FD-----QMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRE---LVRQMEEKEQQLKQDRENQVRHLE 1658
Cdd:PRK05771   178 YVyvvvvVLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEELEEIEKEresLLEELKELAKKYLEELLALYEYLE 257

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2024469763 1659 QKVQEREAKIESLEEKMKS-------VRDSTELErEMLQKIESTKAAVE 1700
Cdd:PRK05771   258 IELERAEALSKFLKTDKTFaiegwvpEDRVKKLK-ELIDKATGGSAYVE 305
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1015-1903 3.42e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.20  E-value: 3.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1015 NDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQeKEQELGDLKEKLATFSAEKEGSRTEI 1094
Cdd:TIGR01612  524 NIIGFDIDQNIKAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIH-LEKEIKDLFDKYLEIDDEIIYINKLK 602

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1095 TRLKE---------EQVKRNETLKQLQEELKQSLAQMSALSNSE------------SGLKAQLQKL-EGDLSQSLKEKSg 1152
Cdd:TIGR01612  603 LELKEkiknisdknEYIKKAIDLKKIIENNNAYIDELAKISPYQvpehlknkdkiySTIKSELSKIyEDDIDALYNELS- 681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1153 lqeQISRQKAIEE-KDKARITELADKLKTLEEKLQTLQSS---------------------------HSKDRENYEKKIE 1204
Cdd:TIGR01612  682 ---SIVKENAIDNtEDKAKLDDLKSKIDKEYDKIQNMETAtvelhlsnienkknelldiiveikkhiHGEINKDLNKILE 758

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1205 AFQQQEtevKELVAQLDAYWKSAEVLLQTKS--NELIEKCNEKIGIVTCKIADCERQATKVKE---AVIIKMNKSVQQLQ 1279
Cdd:TIGR01612  759 DFKNKE---KELSNKINDYAKEKDELNKYKSkiSEIKNHYNDQINIDNIKDEDAKQNYDKSKEyikTISIKEDEIFKIIN 835

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1280 EkdnvIKSMRDDIEGLVTEKEQLqkEGGHQKQAATEKETCitqlrKELSENINAVTSlREDLQEKESEISTLNKTINELN 1359
Cdd:TIGR01612  836 E----MKFMKDDFLNKVDKFINF--ENNCKEKIDSEHEQF-----AELTNKIKAEIS-DDKLNDYEKKFNDSKSLINEIN 903

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1360 VRLesmvsltekeaaisllstqhqEERLQLINQVQELSSSVELLRQEKASaleqvdhcTAKLSEWKTKAQTRFTQNHETI 1439
Cdd:TIGR01612  904 KSI---------------------EEEYQNINTLKKVDEYIKICENTKES--------IEKFHNKQNILKEILNKNIDTI 954

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1440 KDLQS-----KLEVSNTQATKKgEELDKLKEELA---QQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEE 1511
Cdd:TIGR01612  955 KESNLieksyKDKFDNTLIDKI-NELDKAFKDASlndYEAKNNELIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQ 1033

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1512 HI--AQKTSENDSLKEELKRYHEQKDMEqKEVAWQLQQAEKVAFEKD----SRLKEAEEKvLNLENEIGSLKAECEAKER 1585
Cdd:TIGR01612 1034 KIedANKNIPNIEIAIHTSIYNIIDEIE-KEIGKNIELLNKEILEEAeiniTNFNEIKEK-LKHYNFDDFGKEENIKYAD 1111

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1586 EFDQMKSAILKSKEEELkeleerlnaENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDrenQVRHLEQKVQERE 1665
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKID---------HHIKALEEIKKKSENYIDEIKAQINDLEDVADKAISND---DPEEIEKKIENIV 1179

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1666 AKIesleEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVI---KSVQQTHEEKINKLQKDLIEKNKLLQKYeseqreg 1742
Cdd:TIGR01612 1180 TKI----DKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLsygKNLGKLFLEKIDEEKKKSEHMIKAMEAY------- 1248

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1743 IDSLLELQSKQEELLKKLECAEKRHREEQSVTEGlreelEEQAKKYSLLVDEHARCGGDLASSREELKAKEQKNLGMENI 1822
Cdd:TIGR01612 1249 IEDLDEIKEKSPEIENEMGIEMDIKAEMETFNIS-----HDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDI 1323

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1823 MGDFQKKMQEKDAVSHSLEQKVKELED--NLAKVNEVHK--TEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAE-EK 1897
Cdd:TIGR01612 1324 KKELQKNLLDAQKHNSDINLYLNEIANiyNILKLNKIKKiiDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINlEE 1403


                   ....*.
gi 2024469763 1898 AKSGLE 1903
Cdd:TIGR01612 1404 CKSKIE 1409
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 277-605 3.52e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.88  E-value: 3.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  277 VKTLETLNQRvKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQ 356
Cdd:pfam17380  278 VQHQKAVSER-QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  357 -----LEQDKGMVIAETKRQMHEtLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARK- 430
Cdd:pfam17380  357 erkreLERIRQEEIAMEISRMRE-LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQr 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  431 KLQTEMDEKIKAVEKANEEErVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATK--DQELNERLQAQEREfqE 508
Cdd:pfam17380  436 EVRRLEEERAREMERVRLEE-QERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKilEKELEERKQAMIEE--E 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  509 KMKAALEKNQSECLKTLQEQEQQeslaLEELELQKKAIQSECDKKLEEMHQEVETFKTRILELEsslakcsqddkKRSEE 588
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEERR----REAEEERRKQQEMEERRRIQEQMRKATEERSRLEAME-----------REREM 577

                          330
                   ....*....|....*..
gi 2024469763  589 LSTLMDSEKKQHNKEVS 605
Cdd:pfam17380  578 MRQIVESEKARAEYEAT 594
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1621-2020 3.80e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 3.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1621 KKKAEQKIGSIKRELVRQMEEKEQQLKQ-DRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAV 1699
Cdd:COG4717     93 LQEELEELEEELEELEAELEELREELEKlEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAEL 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1700 EQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREgidsLLELQSKQEELLKKLECAEKRHREEQsvtegLRE 1779
Cdd:COG4717    173 AELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEE----LEEAQEELEELEEELEQLENELEAAA-----LEE 243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1780 ELEEQAKKYSLL--VDEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELED-------N 1850
Cdd:COG4717    244 RLKEARLLLLIAaaLLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEEleeeeleE 323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1851 LAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKaksglELQKLLGDMQNQQKDLQAKLEEAEREKQ 1930
Cdd:COG4717    324 LLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQ-----EIAALLAEAGVEDEEELRAALEQAEEYQ 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1931 KLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHSSTLKQLmREFNTQLaqKEMELETAVKETI 2010
Cdd:COG4717    399 ELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREEL-AELEAEL--EQLEEDGELAELL 475

                          410
                   ....*....|
gi 2024469763 2011 SKAQEVESEL 2020
Cdd:COG4717    476 QELEELKAEL 485
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1124-1364 3.95e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1124 ALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQsshsKDRENYEKKI 1203
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALE----AELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1204 EAFQQQETEVKELVA-QLDAYWKS-----AEVLLQTKSNELIEkcnekigivtcKIADCERQATKVKEAVIIKMNKSVQQ 1277
Cdd:COG4942     93 AELRAELEAQKEELAeLLRALYRLgrqppLALLLSPEDFLDAV-----------RRLQYLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1278 LQEKDNVIKSMRDDIEGLVTEKEQLQKEgghQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINE 1357
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   ....*..
gi 2024469763 1358 LNVRLES 1364
Cdd:COG4942    239 AAERTPA 245
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
819-1371 4.04e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 4.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  819 EELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQsDENTQKAMSLTQQYESQLKDLQEE 898
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  899 ADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATE-ERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKklAEQ 977
Cdd:PRK03918   258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKE--LEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  978 ESKLKKELENKQLEFSQKESEFN--AKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEIsrswekklnqqa 1055
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEELEerHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEI------------ 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1056 EELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQvkRNETLKQLQEELKQSLAQMSALSNSESGLKAQ 1135
Cdd:PRK03918   404 EEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEH--RKELLEEYTAELKRIEKELKEIEEKERKLRKE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1136 LQKLEGDLSqslkeksglqeqisrqkaiEEKDKARITELADKLKTLEEKLQTLqsshskDRENYEKKIEAFQQQETEVKE 1215
Cdd:PRK03918   482 LRELEKVLK-------------------KESELIKLKELAEQLKELEEKLKKY------NLEELEKKAEEYEKLKEKLIK 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1216 LVAQLDAYWKSAEVLLQTKSNelIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQE---KDNVIKSMRDDI 1292
Cdd:PRK03918   537 LKGEIKSLKKELEKLEELKKK--LAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPfynEYLELKDAEKEL 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1293 EGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSE-----NINAVTSLREDLQEKESEISTLNKTINELNVRLESMVS 1367
Cdd:PRK03918   615 EREEKELKKLEEELDKAFEELAETEKRLEELRKELEElekkySEEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694


                   ....
gi 2024469763 1368 LTEK 1371
Cdd:PRK03918   695 TLEK 698
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1053-1236 4.21e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 4.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1053 QQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGL 1132
Cdd:COG3883     26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYL 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1133 KA---------------QLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRE 1197
Cdd:COG3883    106 DVllgsesfsdfldrlsALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLA 185

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2024469763 1198 NYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSN 1236
Cdd:COG3883    186 QLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
PRK01156 PRK01156
chromosome segregation protein; Provisional
 892-1365 4.36e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 45.66  E-value: 4.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  892 LKDLQEEA---DKAKQTLTERENDIEHVKKvqneEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKS--KEM 966
Cdd:PRK01156   175 IDMLRAEIsniDYLEEKLKSSNLELENIKK----QIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSslEDM 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  967 QETFKKKLAEQESKLKKELEnKQLEFSQKESEFNAKMLEMAHASSAGIND---------AVSKLESNQKEQLESLAEAHK 1037
Cdd:PRK01156   251 KNRYESEIKTAESDLSMELE-KNNYYKELEERHMKIINDPVYKNRNYINDyfkykndieNKKQILSNIDAEINKYHAIIK 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1038 R--ELEEISRSWEKK------LNQQAEELQEkHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLK 1109
Cdd:PRK01156   330 KlsVLQKDYNDYIKKksryddLNNQILELEG-YEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIK 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1110 QLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSL-----------------------------KEKSGLQEQISRQ 1160
Cdd:PRK01156   409 KELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMemlngqsvcpvcgttlgeeksnhiinhynEKKSRLEEKIREI 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1161 kaieEKDKARITELADKLKTLEEKLQT-----------LQSSHSKDRENYEKKIEAFQQQETEVKELVAQ--------LD 1221
Cdd:PRK01156   489 ----EIEVKDIDEKIVDLKKRKEYLESeeinksineynKIESARADLEDIKIKINELKDKHDKYEEIKNRykslkledLD 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1222 AYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVK----------EAVIIKMNKSVQQLQEKDNVI---KSM 1288
Cdd:PRK01156   565 SKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEigfpddksyiDKSIREIENEANNLNNKYNEIqenKIL 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1289 RDDIEGLVTE-KEQLQKEGGHQKQAAT------EKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTINELNVR 1361
Cdd:PRK01156   645 IEKLRGKIDNyKKQIAEIDSIIPDLKEitsrinDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINET 724


                   ....
gi 2024469763 1362 LESM 1365
Cdd:PRK01156   725 LESM 728
PRK01156 PRK01156
chromosome segregation protein; Provisional
 553-1084 4.51e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 45.66  E-value: 4.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  553 KLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDseKKQHNKE-------VSDIVEKHKEELENV--KQQQE 623
Cdd:PRK01156   191 KLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMD--DYNNLKSalnelssLEDMKNRYESEIKTAesDLSME 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  624 KLWTEKLQILQQQHV-IEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQ-- 700
Cdd:PRK01156   269 LEKNNYYKELEERHMkIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSry 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  701 -DLEQELSELK---SKVGEAKQEFEGKLEAERNQHKE------EVEIMLKEHEISIQDVEKVLKE---ELNQMKQSLEEK 767
Cdd:PRK01156   349 dDLNNQILELEgyeMDYNSYLKSIESLKKKIEEYSKNiermsaFISEILKIQEIDPDAIKKELNEinvKLQDISSKVSSL 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  768 ERLLEEAKTREQELKESAQRSEAELV-QVSARLM--EASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVR 844
Cdd:PRK01156   429 NQRIRALRENLDELSRNMEMLNGQSVcPVCGTTLgeEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEY 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  845 TEC-QLNEVKNELELYISQVHELKQQLQEQSD--ENTQKAMSLTQQYES-QLKDLQEEADKAKQTLTEREN-DIEHVKKV 919
Cdd:PRK01156   509 LESeEINKSINEYNKIESARADLEDIKIKINElkDKHDKYEEIKNRYKSlKLEDLDSKRTSWLNALAVISLiDIETNRSR 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  920 QNEEMEELKQKLLATEERISTLQGD---YENKLKRQENKMEKMKQKSKEMQEtfKKKLAEqesKLKKELENKQLEFSQKE 996
Cdd:PRK01156   589 SNEIKKQLNDLESRLQEIEIGFPDDksyIDKSIREIENEANNLNNKYNEIQE--NKILIE---KLRGKIDNYKKQIAEID 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  997 SEFNAKMLEMAHASSagINDAVSKLESNQKEQLESLAEahKRELEEISRSWEKKLNQQAEELQEKHEmELQEKEQELGDL 1076
Cdd:PRK01156   664 SIIPDLKEITSRIND--IEDNLKKSRKALDDAKANRAR--LESTIEILRTRINELSDRINDINETLE-SMKKIKKAIGDL 738


                   ....*...
gi 2024469763 1077 KEKLATFS 1084
Cdd:PRK01156   739 KRLREAFD 746
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 115-625 4.64e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 4.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  115 SDIESETEEVSGNADSLskEQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGILSQSQDKALRRIGELREELQ 194
Cdd:COG1196    302 QDIARLEERRRELEERL--EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  195 MDQQAKKHLQEEFDASLEEKDQLISVLQTQVSLLKQRLQngqigielpdpnnqsepqvqsQTKEINAENIVEPGSNEGNE 274
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER---------------------LEEELEELEEALAELEEEEE 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  275 DSVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLI 354
Cdd:COG1196    439 EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  355 EQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGmAQRTEEARKKLQT 434
Cdd:COG1196    519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRA-RAALAAALARGAI 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  435 EMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAAL 514
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  515 EKNQSECLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMD 594
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                          490       500       510
                   ....*....|....*....|....*....|.
gi 2024469763  595 SEKKqhnkevsdiVEKHKEELENVKQQQEKL 625
Cdd:COG1196    758 EPPD---------LEELERELERLEREIEAL 779
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 309-516 4.78e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  309 AQLTNEKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAKNLIEQLEQDkgmvIAETKRQMHETlemkEEEVAQLRA 388
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR----IRALEQELAAL----EAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  389 RIKQITTQGEELKEQKEKFERAA-----------------FEELEKALGMAQRTEEARKKLQTEMD---EKIKAVEKANE 448
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALyrlgrqpplalllspedFLDAVRRLQYLKYLAPARREQAEELRadlAELAALRAELE 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024469763  449 EERVNLQQELTRVKQEVVEiMKKSSEDRVAELEKLHKEEmaTKDQELNERLQAQEREFQEKMKAALEK 516
Cdd:COG4942    171 AERAELEALLAELEEERAA-LEALKAERQKLLARLEKEL--AELAAELAELQQEAEELEALIARLEAE 235
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 978-1635 4.84e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.60  E-value: 4.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  978 ESKLKKELENKQLEFSQKESEFNAkmLEMAHASSAGINDAVSKLESNQKEQLESLAEAhKRELEEISRSWEKKLNQQAEE 1057
Cdd:pfam12128  229 DIQAIAGIMKIRPEFTKLQQEFNT--LESAELRLSHLHFGYKSDETLIASRQEERQET-SAELNQLLRTLDDQWKEKRDE 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1058 LQekhemelqekeQELGDLKEKLATFSAEKEGSRTEITRLKEEQVkrnETLKQLQEELKQSLAQMSALSNSESGLKAQLQ 1137
Cdd:pfam12128  306 LN-----------GELSAADAAVAKDRSELEALEDQHGAFLDADI---ETAAADQEQLPSWQSELENLEERLKALTGKHQ 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1138 KLEGDLSqslKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEklQTLQSSHSKDRENYEKKIEAFQQQETEVKELV 1217
Cdd:pfam12128  372 DVTAKYN---RRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAE--DDLQALESELREQLEAGKLEFNEEEYRLKSRL 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1218 AQL-----DAYWKSAEVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEA------VIIKMNKSVQQLQEKDNVIK 1286
Cdd:pfam12128  447 GELklrlnQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRrdqaseALRQASRRLEERQSALDELE 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1287 SMRD------------------DIEGLVTEKEQLQKEGGHQKQAATEKETCIT---------------------QLRKEL 1327
Cdd:pfam12128  527 LQLFpqagtllhflrkeapdweQSIGKVISPELLHRTDLDPEVWDGSVGGELNlygvkldlkridvpewaaseeELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1328 SENINAVTSLREDLQEKESEISTLNKTINELNVRLE-SMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQE 1406
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASREETfARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNS 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1407 KASALEQVDHctaKLSEWKTKAQTRFTQNheTIKDLQSKLEVSNTqatkKGEELDKLKEELAQQGKDLDSLKSVLEEKEN 1486
Cdd:pfam12128  687 LEAQLKQLDK---KHQAWLEEQKEQKREA--RTEKQAYWQVVEGA----LDAQLALLKAAIAARRSGAKAELKALETWYK 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1487 RIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSRLK----EA 1562
Cdd:pfam12128  758 RDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLArliaDT 837

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024469763 1563 EEKVLNLENEIGSL-KAECEAKE--REFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKREL 1635
Cdd:pfam12128  838 KLRRAKLEMERKASeKQQVRLSEnlRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYV 913
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1697-1928 5.04e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1697 AAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEG 1776
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1777 LREELEEQAKKYSLLVDEHARCGgdlASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNE 1856
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLG---RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024469763 1857 vHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAERE 1928
Cdd:COG4942    172 -ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
774-941 5.10e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 5.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  774 AKTREQELKESAQRSEAELVQVSARLMEASlsqqntsnEQAKQYEEELAKLQQKLMDLKGEKL-QLSEQLVRTECQLNEV 852
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLE--------ARLDALREELDELEAQIRGNGGDRLeQLEREIERLERELEER 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  853 KNELELYISQVHELKQQLQEQSD---ENTQKAMSLTQQYESQLKDLQEEADKAKQTLTErendiehvkkvQNEEMEELKQ 929
Cdd:COG4913    358 ERRRARLEALLAALGLPLPASAEefaALRAEAAALLEALEEELEALEEALAEAEAALRD-----------LRRELRELEA 426

                          170
                   ....*....|..
gi 2024469763  930 KLLATEERISTL 941
Cdd:COG4913    427 EIASLERRKSNI 438
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 900-1070 5.23e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 45.20  E-value: 5.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  900 DKAKQTLTERENDIEHV-KKVQNEEMEeLKQKLLATEEristlqgdyenKLKRQENKMEKMKQKSKEMQETFKKKLAEQE 978
Cdd:PRK00409   505 EEAKKLIGEDKEKLNELiASLEELERE-LEQKAEEAEA-----------LLKEAEKLKEELEEKKEKLQEEEDKLLEEAE 572

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  979 SKLKKELEN---------KQLEFSQKE--SEFNAKMLEMAHASsagINDAVSKLESNQKEQleslaEAHKRELEEISRSW 1047
Cdd:PRK00409   573 KEAQQAIKEakkeadeiiKELRQLQKGgyASVKAHELIEARKR---LNKANEKKEKKKKKQ-----KEKQEELKVGDEVK 644

                          170       180
                   ....*....|....*....|...
gi 2024469763 1048 EKKLNQQAEELQEKHEMELQEKE 1070
Cdd:PRK00409   645 YLSLGQKGEVLSIPDDKEAIVQA 667
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
454-903 6.07e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 6.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  454 LQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQES 533
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  534 LALEELELQK-KAIQSECDKKLEEMHQEVETFKtrilELESSLAKCSQDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHK 612
Cdd:COG4717    127 LLPLYQELEAlEAELAELPERLEELEERLEELR----ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  613 E---ELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLS 689
Cdd:COG4717    203 ElqqRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  690 SELSEALKVRQDLEQelselksKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKER 769
Cdd:COG4717    283 LGLLALLFLLLAREK-------ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLRE 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  770 LLEEAKTREQELKESAQRSEAELVQVSarlMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKL---------QLSE 840
Cdd:COG4717    356 AEELEEELQLEELEQEIAALLAEAGVE---DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEellealdeeELEE 432

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024469763  841 QLVRTECQLNEVKNELELYISQVHELKQQLQE-QSDENTQKAMSLTQQYESQLKDLQEEADKAK 903
Cdd:COG4717    433 ELEELEEELEELEEELEELREELAELEAELEQlEEDGELAELLQELEELKAELRELAEEWAALK 496
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1544-1953 6.61e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 6.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1544 QLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKK 1623
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1624 AEQKigsikRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEK 1703
Cdd:COG4717    155 LEEL-----RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1704 NEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEE 1783
Cdd:COG4717    230 EQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQA 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1784 QAKKYSLlvdEHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKV--KELEDNLAKVNEVHKTE 1861
Cdd:COG4717    310 LPALEEL---EEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEleQEIAALLAEAGVEDEEE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1862 MEDRSLKYEEnLKSLQQQLEERNDRLKALEENAEEKAKSGL--ELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSL 1939
Cdd:COG4717    387 LRAALEQAEE-YQELKEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELAELEAELEQL 465

                          410
                   ....*....|....
gi 2024469763 1940 QKDLRTLRKEHQQE 1953
Cdd:COG4717    466 EEDGELAELLQELE 479
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 871-1152 7.06e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 7.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  871 QEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDyenklk 950
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE------ 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  951 rqenkmekmkqkskemQETFKKKLAEQESKLKkelenKQLEFSQKESEFNAKMLEMahaSSAGINDAVSKLESnqkeqLE 1030
Cdd:COG4942     92 ----------------IAELRAELEAQKEELA-----ELLRALYRLGRQPPLALLL---SPEDFLDAVRRLQY-----LK 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1031 SLAEAhkreleeisrswekkLNQQAEELQEKHEmELQEKEQELGDLKEKLATFSAEKEgsrTEITRLKEEQVKRNETLKQ 1110
Cdd:COG4942    143 YLAPA---------------RREQAEELRADLA-ELAALRAELEAERAELEALLAELE---EERAALEALKAERQKLLAR 203

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024469763 1111 LQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSG 1152
Cdd:COG4942    204 LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 281-889 8.46e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 8.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  281 ETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQE---------QLEERLQELEKMKDLHMGEKTKLITQLRDAK 351
Cdd:TIGR00618  215 DTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEqlkkqqllkQLRARIEELRAQEAVLEETQERINRARKAAP 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  352 NL-----IEQLEQDKGMVIAETKRQMHE--TLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQR 424
Cdd:TIGR00618  295 LAahikaVTQIEQQAQRIHTELQSKMRSraKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQ 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  425 TEEARKKLQ-----TEMDEKIKAVEKANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERL 499
Cdd:TIGR00618  375 HTLTQHIHTlqqqkTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  500 QAQEREFQEKMKAALEKNQSEC-LKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEV------ETFKTRILELE 572
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQtKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARqdidnpGPLTRRMQRGE 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  573 SSLAKCSQDDKKRSEELSTLMDSEKKQHNK----------------EVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQ 636
Cdd:TIGR00618  535 QTYAQLETSEEDVYHQLTSERKQRASLKEQmqeiqqsfsiltqcdnRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQ 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  637 HVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSEL-SEALKVRQDLEQELSELKSKVGE 715
Cdd:TIGR00618  615 HALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLpKELLASRQLALQKMQSEKEQLTY 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  716 AKQEFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLK-----EELNQMKQSLEEKERLLEEAKTREQELKESAQRSEA 790
Cdd:TIGR00618  695 WKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDlaareDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAAL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  791 ELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQlneVKNELELYISQVHELKQQL 870
Cdd:TIGR00618  775 QTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQ---FLSRLEEKSATLGEITHQL 851

                          650
                   ....*....|....*....
gi 2024469763  871 QEQSDENTQKAMSLTQQYE 889
Cdd:TIGR00618  852 LKYEECSKQLAQLTQEQAK 870
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 889-1193 1.03e-03

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 44.07  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  889 ESQLKDLQEEADKAKQTLTERENDIEHVKKVQneEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEM-- 966
Cdd:pfam09726  252 EKKNSGTSSGSDSKKSHNHNIHNLNHVDSKLQ--EKEYMENHSNSKRLNISTSPGSEEDLLVRESVSSKSSSSSSSSNkn 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  967 QETFKKKLAEQ----------------ESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLE 1030
Cdd:pfam09726  330 YKNASGGSANSsnssprshshnsgsvtSSSSSKNSKKQKGPGGKSGARHKDPAENCIPNNQLSKPDALVRLEQDIKKLKA 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1031 SLAEAHKRELEEISR-----SWEKKLNQQAEELQEKHEMeLQEKEQELGDLKEKlatfsaEKEGSRTEITRLKEEQVKRN 1105
Cdd:pfam09726  410 ELQASRQTEQELRSQissltSLERSLKSELGQLRQENDL-LQTKLHNAVSAKQK------DKQTVQQLEKRLKAEQEARA 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1106 ETLKQLQEELK----------QSLAQMSA--------LSNSESGLKAQLQKLEGDLsqSLKEKSGLQEQISRQKAIEEKD 1167
Cdd:pfam09726  483 SAEKQLAEEKKrkkeeeataaRAVALAAAsrgectesLKQRKRELESEIKKLTHDI--KLKEEQIRELEIKVQELRKYKE 560

                          330       340
                   ....*....|....*....|....*..
gi 2024469763 1168 KARITE-LADKLKTLEEKLQTLQSSHS 1193
Cdd:pfam09726  561 SEKDTEvLMSALSAMQDKNQHLENSLS 587
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 374-591 1.07e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  374 ETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAfEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKANEEERVN 453
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-AALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  454 LQQELTRVKQEVVEIMKKSSEDRVAEL----EKLHKEEMATKDQELNERLQAQEREFQEKMKA-----ALEKNQSECLKT 524
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAElaalrAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763  525 LQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELST 591
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 667-783 1.07e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.43  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  667 IEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEISI 746
Cdd:PRK00409   518 LNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQ 597

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2024469763  747 Q-----DVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKE 783
Cdd:PRK00409   598 KggyasVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELKV 639
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1535-1873 1.10e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.30  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1535 DMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEelkeleerlNAENS 1614
Cdd:COG5022    788 DYELKWRLFIKLQPLLSLLGSRKEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGR---------SLKAK 858

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1615 CKLADLKKKAEQKIGSIKRELVRQmeeKEQQLKQDRENqVRHLEQKVQEREAKIESLEEKMKSVR---------DSTELE 1685
Cdd:COG5022    859 KRFSLLKKETIYLQSAQRVELAER---QLQELKIDVKS-ISSLKLVNLELESEIIELKKSLSSDLienlefkteLIARLK 934

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1686 ReMLQKIESTkaaVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEK 1765
Cdd:COG5022    935 K-LLNNIDLE---EGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGA 1010

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1766 RHREEQSVTEgLREELEEQAKKYSLLVDEHarcggdlASSREELKAKEQKNLGMENI----MGDFQKKMQEKDAVSHSLE 1841
Cdd:COG5022   1011 LQESTKQLKE-LPVEVAELQSASKIISSES-------TELSILKPLQKLKGLLLLENnqlqARYKALKLRRENSLLDDKQ 1082

                          330       340       350
                   ....*....|....*....|....*....|..
gi 2024469763 1842 QKVKELEDNLAKVNEVHKTEMEDRSLKYEENL 1873
Cdd:COG5022   1083 LYQLESTENLLKTINVKDLEVTNRNLVKPANV 1114
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
285-519 1.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  285 QRVKRQENLLQRckemIRSHKERCAQLTNEKEALQEQLEE-RLQELEKMKDLhmgektklitqlrdAKNLIEQLEQDkgm 363
Cdd:COG4913    245 EDAREQIELLEP----IRELAERYAAARERLAELEYLRAAlRLWFAQRRLEL--------------LEAELEELRAE--- 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  364 viaetkrqmhetLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQTEMDEKIKAV 443
Cdd:COG4913    304 ------------LARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL 371

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763  444 E---KANEEERVNLQQELTRVKQEVVEImKKSSEDRVAELEKLHkeematkdQELNERLQAQEREFqekmkAALEKNQS 519
Cdd:COG4913    372 GlplPASAEEFAALRAEAAALLEALEEE-LEALEEALAEAEAAL--------RDLRRELRELEAEI-----ASLERRKS 436
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1038-1222 1.21e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1038 RELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQ 1117
Cdd:COG4372     19 RPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQ 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1118 SLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSK-DR 1196
Cdd:COG4372     99 AQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQAlSE 178

                          170       180
                   ....*....|....*....|....*.
gi 2024469763 1197 ENYEKKIEAFQQQETEVKELVAQLDA 1222
Cdd:COG4372    179 AEAEQALDELLKEANRNAEKEEELAE 204
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 156-842 1.22e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  156 ELVSAYQVIQREKKKLQGILSQSQdKALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSLLKQRLQNG 235
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLE-SAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  236 QIGIELPDPNNQSEPQV-QSQTKEINAENIVEPGSNEGNEDSVKT-LETLNQRVKRQENllqrckemirSHKERCAQLTN 313
Cdd:pfam12128  310 LSAADAAVAKDRSELEAlEDQHGAFLDADIETAAADQEQLPSWQSeLENLEERLKALTG----------KHQDVTAKYNR 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  314 EKEALQEQLEERLQELEKMKDLHMGEKTKLITQLRDAknlIEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQI 393
Cdd:pfam12128  380 RRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDD---LQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQA 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  394 TTQGEELKEQKEKFER--AAFEELEKALGMAQRTEEARKKLQTEMDEKIKAVEKANE--EERVN----LQQELTRVKQEV 465
Cdd:pfam12128  457 TATPELLLQLENFDERieRAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRrlEERQSaldeLELQLFPQAGTL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  466 VEIMKKSSED------RVAELEKLHKEEMatkDQELNERLQAQEREFQeKMKAALEKNQSECLKTLQEQEQQESLALEEL 539
Cdd:pfam12128  537 LHFLRKEAPDweqsigKVISPELLHRTDL---DPEVWDGSVGGELNLY-GVKLDLKRIDVPEWAASEEELRERLDKAEEA 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  540 ELQKKAIQSECDKKLEEMHQEVETfktriLELESSLAKCS-QDDKKRSEELSTLMDSEKKQHNKEVSDIVEKHKEELENV 618
Cdd:pfam12128  613 LQSAREKQAAAEEQLVQANGELEK-----ASREETFARTAlKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  619 KQQQEKLWTEKLQILQQQHVIEIEKMREKQE--QEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEAL 696
Cdd:pfam12128  688 EAQLKQLDKKHQAWLEEQKEQKREARTEKQAywQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDP 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  697 KVRQDLEQELSELKSKVGEAKQ------EFEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERL 770
Cdd:pfam12128  768 DVIAKLKREIRTLERKIERIAVrrqevlRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEME 847

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024469763  771 LEEAKTREQELKESAQRSEAELVQVsarlmeASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQL 842
Cdd:pfam12128  848 RKASEKQQVRLSENLRGLRCEMSKL------ATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYV 913
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 991-1205 1.23e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.15  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  991 EFSQKESEFNakmLEMAHASSAGINDAVSKLES-NQKEQL--ESLAEAHKRELEEISRSWEKKLNQQAEELQEKHE--ME 1065
Cdd:PRK05771    35 DLKEELSNER---LRKLRSLLTKLSEALDKLRSyLPKLNPlrEEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEeiSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1066 LQEKEQELGDLK---EKLATFSAE----KEGSRTEIT--RLKEEQVKRNETLKQLQEELKQSLAQMS------ALSNSES 1130
Cdd:PRK05771   112 LENEIKELEQEIerlEPWGNFDLDlsllLGFKYVSVFvgTVPEDKLEELKLESDVENVEYISTDKGYvyvvvvVLKELSD 191

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1131 GLKAQLQKLeGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEA 1205
Cdd:PRK05771   192 EVEEELKKL-GFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEA 265
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
952-1190 1.29e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  952 QENKMEKMKQKSKEMQETFKKKLAEQESKLKkELENKQLEFSQKESEFNAkmlemahasSAGINDAVSKLESNQKEQLEs 1031
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELE-EAEAALEEFRQKNGLVDL---------SEEAKLLLQQLSELESQLAE- 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1032 lAEAHKRELEEISRSWEKKLNQQAEELQEKHE-MELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEqvkRNETLKQ 1110
Cdd:COG3206    231 -ARAELAEAEARLAALRAQLGSGPDALPELLQsPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQ---IAALRAQ 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1111 LQEELKQSLAQmsaLSNSESGLKAQLQKLEGDLSQslkeksgLQEQISRQKAIEekdkARITELADKLKTLEEKLQTLQS 1190
Cdd:COG3206    307 LQQEAQRILAS---LEAELEALQAREASLQAQLAQ-------LEARLAELPELE----AELRRLEREVEVARELYESLLQ 372
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1063-1241 1.37e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1063 EMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGD 1142
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1143 LSQSLKEKSGLQ------------EQISRQKAIEEKDKARITELA---DKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQ 1207
Cdd:COG3883     95 LYRSGGSVSYLDvllgsesfsdflDRLSALSKIADADADLLEELKadkAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190
                   ....*....|....*....|....*....|....
gi 2024469763 1208 QQETEVKELVAQLDAYWKSAEVLLQTKSNELIEK 1241
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAA 208
PRK12704 PRK12704
phosphodiesterase; Provisional
 314-442 1.40e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 1.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  314 EKEALQEQLEERLQELEKMKDLhmgeKTKLITQLRDAKNLIEQLEQdKGMVIAETKRQMHETLEMKEEEVAQLRARIKQI 393
Cdd:PRK12704    48 KKEAEAIKKEALLEAKEEIHKL----RNEFEKELRERRNELQKLEK-RLLQKEENLDRKLELLEKREEELEKKEKELEQK 122

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 2024469763  394 TTQGEELKEQKEKFERAAFEELEKALGMAQrtEEARKKLQTEMDEKIKA 442
Cdd:PRK12704   123 QQELEKKEEELEELIEEQLQELERISGLTA--EEAKEILLEKVEEEARH 169
46 PHA02562
endonuclease subunit; Provisional
 284-474 1.44e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.85  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  284 NQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDlhmgEKTKLITQLRDAKNLIEQLEqdKGM 363
Cdd:PHA02562   212 GENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNT----AAAKIKSKIEQFQKVIKMYE--KGG 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  364 VIAETKRQMHETlemkEEEVAQLRARIKQITTQGEELKEQKEKFERAAFEELE---KALGMAQRTEEARKKLQTEmDEKI 440
Cdd:PHA02562   286 VCPTCTQQISEG----PDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEqskKLLELKNKISTNKQSLITL-VDKA 360

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2024469763  441 KAVEKANEE---ERVNLQQELTRVKQEVVEIMKKSSE 474
Cdd:PHA02562   361 KKVKAAIEElqaEFVDNAEELAKLQDELDKIVKTKSE 397
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1502-1706 1.45e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1502 QAARVAE------LEEHIAQKTSENDS----LKEELKRYheQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLEN 1571
Cdd:COG3206    149 LAAAVANalaeayLEQNLELRREEARKalefLEEQLPEL--RKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELES 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1572 EIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIK------RELVRQMEEKEQQ 1645
Cdd:COG3206    227 QLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTpnhpdvIALRAQIAALRAQ 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1646 LKQ-------DRENQVRHLEQKVQEREAKIESLEEKMKSV----RDSTELERE----------MLQKIESTKAAVEQEKN 1704
Cdd:COG3206    307 LQQeaqrilaSLEAELEALQAREASLQAQLAQLEARLAELpeleAELRRLEREvevarelyesLLQRLEEARLAEALTVG 386


                   ..
gi 2024469763 1705 EV 1706
Cdd:COG3206    387 NV 388
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
336-845 1.47e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  336 HMGEKTKLITQLRDAKNLIEQLEQdkgmviaetkrqMHETLEMKEEEVAQLRarikQITTQGEELKEQKEkfERAAFEEL 415
Cdd:COG4913    216 YMLEEPDTFEAADALVEHFDDLER------------AHEALEDAREQIELLE----PIRELAERYAAARE--RLAELEYL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  416 EKALGmAQRTEEARKKLQTEMDEKIKAVEKAnEEERVNLQQELTRVKQEVVEIMKKSSEDRVAELEKLhKEEMATKDQEL 495
Cdd:COG4913    278 RAALR-LWFAQRRLELLEAELEELRAELARL-EAELERLEARLDALREELDELEAQIRGNGGDRLEQL-EREIERLEREL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  496 NERLQAQEReFQEKMK----------AALEKNQSEcLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFK 565
Cdd:COG4913    355 EERERRRAR-LEALLAalglplpasaEEFAALRAE-AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  566 TRILELESSLAK-----CSQDDKKRSE-----ELSTLMDSEKK--------------------QHNKEVSDIVEKHKEEL 615
Cdd:COG4913    433 RRKSNIPARLLAlrdalAEALGLDEAElpfvgELIEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVNRLHLRG 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  616 ----ENVKQQQEKLWTEKLQILQQQHVIEIEK------MREKQEQEIDTILKEKETVFRTH------------IEEMNEK 673
Cdd:COG4913    513 rlvyERVRTGLPDPERPRLDPDSLAGKLDFKPhpfrawLEAELGRRFDYVCVDSPEELRRHpraitragqvkgNGTRHEK 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  674 ---------------TLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKvGEAKQEFEGKLEAERN-----QHKE 733
Cdd:COG4913    593 ddrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQER-REALQRLAEYSWDEIDvasaeREIA 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  734 EVEIMLKEHEISIQDVEKvLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQ 813
Cdd:COG4913    672 ELEAELERLDASSDDLAA-LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2024469763  814 A----------KQYEEELAKLQQKLMDLKGEKLQLSEQLVRT 845
Cdd:COG4913    751 LeerfaaalgdAVERELRENLEERIDALRARLNRAEEELERA 792
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1336-1552 1.49e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 1.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1336 SLREDLQEKESEISTLNKTINELNVRLESMvsltekeaaisllstqhQEERLQLINQVQELSSSVELLRQEKASALEQVD 1415
Cdd:COG3883     20 AKQKELSELQAELEAAQAELDALQAELEEL-----------------NEEYNELQAELEALQAEIDKLQAEIAEAEAEIE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1416 HCTAKLSEWKTKAQtrftQNHETIKDLQSKLEVSN-TQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESE 1494
Cdd:COG3883     83 ERREELGERARALY----RSGGSVSYLDVLLGSESfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAE 158

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024469763 1495 LTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVA 1552
Cdd:COG3883    159 LEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1616-2080 1.74e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.57  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1616 KLADLKKKAEQKIgsikRELVRQMEEKEQQLKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREM-LQKIES 1694
Cdd:pfam15921  246 QLEALKSESQNKI----ELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMyMRQLSD 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1695 TKAAVEQEKNEvIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKrhreEQSVT 1774
Cdd:pfam15921  322 LESTVSQLRSE-LREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREK----ELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1775 EGLREELEEQAKKYSLLVDEHARCGGDLASSREELKA-----KEQKNLGMENIMGDFQKKMQEKDAVShSLEQKVKELED 1849
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEAllkamKSECQGQMERQMAAIQGKNESLEKVS-SLTAQLESTKE 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1850 NLAKVNEvhktEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNqQKDLQAKLEEAEREK 1929
Cdd:pfam15921  476 MLRKVVE----ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQH-LKNEGDHLRNVQTEC 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1930 QKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAV--- 2006
Cdd:pfam15921  551 EALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVsdl 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2007 ---KETISKAQEVESELIENHQIETTQLHKKIAEKDDDLKRTVKKYEEIL---EAREEEMTTKVHELQTQLEELQKEYKQ 2080
Cdd:pfam15921  631 eleKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKrnfRNKSEEMETTTNKLKMQLKSAQSELEQ 710
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1276-1469 1.86e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1276 QQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTI 1355
Cdd:COG4942     34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRAL 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1356 --NELNVRLESMVSLTEKEAAISLLS--TQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHCTAKLSEWKTKAQTR 1431
Cdd:COG4942    114 yrLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEAL 193

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2024469763 1432 FTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQ 1469
Cdd:COG4942    194 KAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
mukB PRK04863
chromosome partition protein MukB;
1622-1968 1.94e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1622 KKAEQKIGSIKRELVRQmEEKEQQLKQdrenQVRHLEQKVQEREAKI--------ESLEEKMKSVRDSTELEREMLQKIE 1693
Cdd:PRK04863   840 RQLNRRRVELERALADH-ESQEQQQRS----QLEQAKEGLSALNRLLprlnlladETLADRVEEIREQLDEAEEAKRFVQ 914

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1694 STKAAVEQEKNEVikSVQQTHEEKINKLQKDLIEKNKLLQkyesEQREGIDSLLELQSKQEELlkKLECAEKRHREEQSV 1773
Cdd:PRK04863   915 QHGNALAQLEPIV--SVLQSDPEQFEQLKQDYQQAQQTQR----DAKQQAFALTEVVQRRAHF--SYEDAAEMLAKNSDL 986

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1774 TEGLREELEEQakkysllvdEHARcggdlASSREELKAKEQKnlgmeniMGDFQKKMQEKDAVSHSLEQKVKELednlak 1853
Cdd:PRK04863   987 NEKLRQRLEQA---------EQER-----TRAREQLRQAQAQ-------LAQYNQVLASLKSSYDAKRQMLQEL------ 1039

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1854 vnevhKTEMEDRSLKYEENLkslQQQLEERNDRL-KALEENAEEKAKSGLELQKLLGDMQNQQKdlqaKLEEAEREKQKL 1932
Cdd:PRK04863  1040 -----KQELQDLGVPADSGA---EERARARRDELhARLSANRSRRNQLEKQLTFCEAEMDNLTK----KLRKLERDYHEM 1107

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 2024469763 1933 RKDVNS----------LQKDLRTLRKEHQQELDIVKKESLEEMEQK 1968
Cdd:PRK04863  1108 REQVVNakagwcavlrLVKDNGVERRLHRRELAYLSADELRSMSDK 1153
mukB PRK04863
chromosome partition protein MukB;
280-546 2.06e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  280 LETLNQRVKRQENLLQRCKEMIRSHKERCaqltnekealqEQLEERLQELEKM-KDLHMGEKTKLITQLRDAKNLIEQLE 358
Cdd:PRK04863   839 LRQLNRRRVELERALADHESQEQQQRSQL-----------EQAKEGLSALNRLlPRLNLLADETLADRVEEIREQLDEAE 907

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  359 QDK------GMVIAETKRQMhETLEMKEEEVAQLRARIKQITTQGEELKEQ----KEKFERAAFEELEKALGMAQRTEEA 428
Cdd:PRK04863   908 EAKrfvqqhGNALAQLEPIV-SVLQSDPEQFEQLKQDYQQAQQTQRDAKQQafalTEVVQRRAHFSYEDAAEMLAKNSDL 986

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  429 RKKLQTEMDEKIKAVEKANEEERvNLQQELTRVKQevVEIMKKSSEDRVAELEKLHKEEMA----TKDQELNERLQAQER 504
Cdd:PRK04863   987 NEKLRQRLEQAEQERTRAREQLR-QAQAQLAQYNQ--VLASLKSSYDAKRQMLQELKQELQdlgvPADSGAEERARARRD 1063

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 2024469763  505 EFQEKM------KAALEKNQSECLKTLQEQEQQESLALEELELQKKAI 546
Cdd:PRK04863  1064 ELHARLsanrsrRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQV 1111
PRK12704 PRK12704
phosphodiesterase; Provisional
 970-1139 2.11e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  970 FKKKLAEQESKLKKELENKQLEFSQKESEFNAKmlemahassagindavsKLESNQKEQLESLAEAHKRELEEISRS--- 1046
Cdd:PRK12704    24 VRKKIAEAKIKEAEEEAKRILEEAKKEAEAIKK-----------------EALLEAKEEIHKLRNEFEKELRERRNElqk 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1047 WEKKLNQQAEELQEKHEmELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQL-QEELKQSLaqmsaL 1125
Cdd:PRK12704    87 LEKRLLQKEENLDRKLE-LLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLtAEEAKEIL-----L 160

                          170
                   ....*....|....
gi 2024469763 1126 SNSESGLKAQLQKL 1139
Cdd:PRK12704   161 EKVEEEARHEAAVL 174
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 819-1232 2.13e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.40  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  819 EELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQSD-----ENTQKAMSLTQQYESQLK 893
Cdd:COG3096    278 NERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDhlnlvQTALRQQEKIERYQEDLE 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  894 DLQEEADKAKQTLTERendiehvkkvqNEEMEELKQKLLATEERISTLQG---DYENKLKRQENKMEKMKQKSKEMQETf 970
Cdd:COG3096    358 ELTERLEEQEEVVEEA-----------AEQLAEAEARLEAAEEEVDSLKSqlaDYQQALDVQQTRAIQYQQAVQALEKA- 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  971 kKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMahassagindavsklesnqkEQLESLAEAHKRELE--------- 1041
Cdd:COG3096    426 -RALCGLPDLTPENAEDYLAAFRAKEQQATEEVLEL--------------------EQKLSVADAARRQFEkayelvcki 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1042 --EISRS--WekklnQQAEELQEKHEmELQEKEQELGDLKEKLAtfsaekegsrtEITRLKEEQVKRNETLKQLQEELKQ 1117
Cdd:COG3096    485 agEVERSqaW-----QTARELLRRYR-SQQALAQRLQQLRAQLA-----------ELEQRLRQQQNAERLLEEFCQRIGQ 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1118 SLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQisrqkaiEEKDKARITELADK---LKTLEEKLQTLQSSHSK 1194
Cdd:COG3096    548 QLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQ-------LEQLRARIKELAARapaWLAAQDALERLREQSGE 620

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 2024469763 1195 DRENYEKKIEAFQQ---QETEVK----ELVAQLDAYWKSAEVLLQ 1232
Cdd:COG3096    621 ALADSQEVTAAMQQlleREREATverdELAARKQALESQIERLSQ 665
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 901-1216 2.21e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 43.02  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  901 KAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQgDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESK 980
Cdd:COG5185    208 KESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLA-QTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANN 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  981 LKKELENKQLEFSQKESEFNAKMLEM-------AHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQ 1053
Cdd:COG5185    287 LIKQFENTKEKIAEYTKSIDIKKATEsleeqlaAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENI 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1054 QAEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNET-LKQLQEELKQSLAQMSALSNSESGL 1132
Cdd:COG5185    367 VGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRqIEELQRQIEQATSSNEEVSKLLNEL 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1133 KAQLQKLEGDLSQSLKEKsglqeQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETE 1212
Cdd:COG5185    447 ISELNKVMREADEESQSR-----LEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQ 521


                   ....
gi 2024469763 1213 VKEL 1216
Cdd:COG5185    522 VAES 525
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 788-983 2.27e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  788 SEAELVQVSARLMEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELK 867
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  868 QQLQEQSDE---------------------------NTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQ 920
Cdd:COG4942     97 AELEAQKEElaellralyrlgrqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024469763  921 NE---EMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKK 983
Cdd:COG4942    177 EAllaELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
652-1081 2.29e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  652 IDTILKEKETVFRTH--IEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFEGKLEAERN 729
Cdd:COG4717     48 LERLEKEADELFKPQgrKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  730 QhkeEVEIMLKEHEISIQDVEKVLkEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNT 809
Cdd:COG4717    128 L---PLYQELEALEAELAELPERL-EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  810 SNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTEcQLNEVKNELELYISQ----VHELKQQLQEQSDENTQKAMSLT 885
Cdd:COG4717    204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAA-LEERLKEARLLLLIAaallALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  886 QQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKE 965
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  966 MQ-----ETFKKKLAEQESKLKKELENKqLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKREL 1040
Cdd:COG4717    363 LQleeleQEIAALLAEAGVEDEEELRAA-LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEEL 441

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 2024469763 1041 EEISRSWEKKLNQQAEELQEKHEME----LQEKEQELGDLKEKLA 1081
Cdd:COG4717    442 EELEEELEELREELAELEAELEQLEedgeLAELLQELEELKAELR 486
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 967-1892 2.29e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.50  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  967 QETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLeSLAEAHKRELEEISRS 1046
Cdd:TIGR00606  103 QKTKKTEFKTLEGVITRYKHGEKVSLSSKCAEIDREMISHLGVSKAVLNNVIFCHQEDSNWPL-SEGKALKQKFDEIFSA 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1047 WE--------KKLNQQAEELQEKHEMELQEKEQ---ELGDLKEKLATFSAEKEGSRtEITRLKEEQVkrnETLKQLQEEL 1115
Cdd:TIGR00606  182 TRyikaletlRQVRQTQGQKVQEHQMELKYLKQykeKACEIRDQITSKEAQLESSR-EIVKSYENEL---DPLKNRLKEI 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1116 KQSLAQMSALSNSESGLKAQLQKLEGDLSQ-SLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQSSH-- 1192
Cdd:TIGR00606  258 EHNLSKIMKLDNEIKALKSRKKQMEKDNSElELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERrl 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1193 -SKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNELIEKCNEKI-GIVTCKIADCERQATKVKEAVIIK 1270
Cdd:TIGR00606  338 lNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIkNFHTLVIERQEDEAKTAAQLCADL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1271 MNKSVQQLQEKDNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLRE-DLQEKESEIS 1349
Cdd:TIGR00606  418 QSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERElSKAEKNSLTE 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1350 TLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEKASALEQVDHC------TAKLSE 1423
Cdd:TIGR00606  498 TLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnKKQLED 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1424 WKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSV--LEEKENRIEKQESELTAELKI 1501
Cdd:TIGR00606  578 WLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSqdEESDLERLKEEIEKSSKQRAM 657

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1502 QAARVAELEEHIAQKTSENDSLKEELKRYHEQKD-----------------MEQKEVAWQLQQAEKVAFEKDSRLKEAEE 1564
Cdd:TIGR00606  658 LAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAelqefisdlqsklrlapDKLKSTESELKKKEKRRDEMLGLAPGRQS 737

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1565 KVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKEq 1644
Cdd:TIGR00606  738 IIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQ- 816

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1645 qlKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTH--EEKINKLQ 1722
Cdd:TIGR00606  817 --GSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQqfEEQLVELS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1723 KDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRH-------REEQSVTEGLREELEE--QAKKYSLLVD 1793
Cdd:TIGR00606  895 TEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAqdkvndiKEKVKNIHGYMKDIENkiQDGKDDYLKQ 974

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1794 EHARCGGDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSL-----EQKVKELEDNLA----KVNEVHKTEMED 1864
Cdd:TIGR00606  975 KETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLtlrkrENELKEVEEELKqhlkEMGQMQVLQMKQ 1054

                          970       980
                   ....*....|....*....|....*...
gi 2024469763 1865 RSLKYEENLKSLQQQLEERNDRLKALEE 1892
Cdd:TIGR00606 1055 EHQKLEENIDLIKRNHVLALGRQKGYEK 1082
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 903-1180 2.29e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 43.02  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  903 KQTLTERENDI-EHVKKVQNEEMEELKQKLLATEERISTLQG-DYENKLKRQENKMEKMKQKSKEMQETFKKKlaeqesK 980
Cdd:pfam07902   48 NQLMIERGNKPtDYVAPVVVEGSGESTGLFKSLEEMLSQLKElNLELTDTKNSNLWSKIKLNNNGMLREYHND------T 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  981 LKKELENKQLEFSQKESEFNAKMLEMAHASSAGI----NDAVSKLESNQKEQLESLaeahKRELEEISRSWEKKLNQQAE 1056
Cdd:pfam07902  122 IKTEIVESAEGIATRISEDTDKKLALINETISGIrreyQDADRQLSSSYQAGIEGL----KATMASDKIGLQAEIQASAQ 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1057 ELQEKHEMELQE---------------KEQELGDLKeklATFSAEKEGSRTEI-TRLKEEQVKRNETLKQLQEELKQSLA 1120
Cdd:pfam07902  198 GLSQRYDNEIRKlsakitttssgtteaYESKLDDLR---AEFTRSNQGMRTELeSKISGLQSTQQSTAYQISQEISNREG 274

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1121 QMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAieeKDKARITELADKLKT 1180
Cdd:pfam07902  275 AVSRVQQDLDSYQRRLQDAEKNYSSLTQTVKGLQSTVSDPNS---KLESRITQLAGLIEQ 331
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1775-1970 2.35e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1775 EGLREELEEQAKKYSLLVDEHarcggDLASSREELKAKEQKnlgmeniMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKV 1854
Cdd:COG3206    185 PELRKELEEAEAALEEFRQKN-----GLVDLSEEAKLLLQQ-------LSELESQLAEARAELAEAEARLAALRAQLGSG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1855 NEVHKTEMEDRSL-KYEENLKSLQQQLEE-------RNDRLKALEEN-AEEKAKSGLELQKLLGDMQNQQKDLQAKLEEA 1925
Cdd:COG3206    253 PDALPELLQSPVIqQLRAQLAELEAELAElsarytpNHPDVIALRAQiAALRAQLQQEAQRILASLEAELEALQAREASL 332

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2024469763 1926 EREKQKLRKDVNSLQKDLRTLRkEHQQELDiVKKESLEEMEQKIR 1970
Cdd:COG3206    333 QAQLAQLEARLAELPELEAELR-RLEREVE-VARELYESLLQRLE 375
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 993-1189 2.43e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  993 SQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKR--ELEEISRSWEKKLNQQAEELQEKhEMELQEKE 1070
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiaALARRIRALEQELAALEAELAEL-EKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1071 QELGDLKEKLATF--SAEKEGSRTEIT-------------------RLKEEQVKRNETLKQLQEELKQSLAQMSALSNSE 1129
Cdd:COG4942     97 AELEAQKEELAELlrALYRLGRQPPLAlllspedfldavrrlqylkYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1130 SGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAieeKDKARITELADKLKTLEEKLQTLQ 1189
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELA---ELAAELAELQQEAEELEALIARLE 233
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1458-1774 2.45e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 2.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1458 EELDKLKEELAQQGKDLdslKSVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEElKRYHEQKDME 1537
Cdd:pfam17380  291 EKFEKMEQERLRQEKEE---KAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQE-ERKRELERIR 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1538 QKEVAWQLqqaekvafekdSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSckl 1617
Cdd:pfam17380  367 QEEIAMEI-----------SRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEA--- 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1618 adlkkkAEQKIGSIKRELVRQMEEKEQQlKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQK-IESTK 1696
Cdd:pfam17380  433 ------RQREVRRLEEERAREMERVRLE-EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKeLEERK 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1697 AAV--EQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGID----------SLLELQSKQEELLKKLECAE 1764
Cdd:pfam17380  506 QAMieEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQeqmrkateerSRLEAMEREREMMRQIVESE 585

                          330
                   ....*....|
gi 2024469763 1765 KRHREEQSVT 1774
Cdd:pfam17380  586 KARAEYEATT 595
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1324-2038 2.54e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.03  E-value: 2.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1324 RKELSENINAVTSLREDLQEKESEISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELL 1403
Cdd:TIGR00618  165 KKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAY 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1404 RQEKASALEQVDHCTAKLSEWKTKAQTrfTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEE 1483
Cdd:TIGR00618  245 LTQKREAQEEQLKKQQLLKQLRARIEE--LRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRS 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1484 KENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKdsrLKEAE 1563
Cdd:TIGR00618  323 RAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQK---LQSLC 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1564 EKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKE 1643
Cdd:TIGR00618  400 KELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1644 QQLKQDREnqvrhleqKVQEREAKIESLEEKMKSVRDST---ELEREMLQKIESTKAAVEQEKNEVIKsvqqtHEEKINK 1720
Cdd:TIGR00618  480 QIHLQETR--------KKAVVLARLLELQEEPCPLCGSCihpNPARQDIDNPGPLTRRMQRGEQTYAQ-----LETSEED 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1721 LQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLEcaekrhrEEQSVTEGLREELEEQAKKYSLLVDEHARcgg 1800
Cdd:TIGR00618  547 VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP-------NLQNITVRLQDLTEKLSEAEDMLACEQHA--- 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1801 dLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLK-SLQQQ 1879
Cdd:TIGR00618  617 -LLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKeQLTYW 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1880 LEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAerekqklrkdvNSLQKDLRTLRKEHQQELDIVKK 1959
Cdd:TIGR00618  696 KEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDAL-----------NQSLKELMHQARTVLKARTEAHF 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1960 ESLEEMEQKIRCEQEDIELKHSSTLKQ-LMREFNTQLAQKEMELETAVKETiSKAQEVESELIenhQIETTQLHKKIAEK 2038
Cdd:TIGR00618  765 NNNEEVTAALQTGAELSHLAAEIQFFNrLREEDTHLLKTLEAEIGQEIPSD-EDILNLQCETL---VQEEEQFLSRLEEK 840
mukB PRK04863
chromosome partition protein MukB;
1381-1701 2.54e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1381 QHQEERLQLINQVqeLSSSVELLRQEKASALEQVDHctaklsewktkaqTRFTQNHETIKDLQSKLEVSNTQATkkgEEL 1460
Cdd:PRK04863   276 RHANERRVHLEEA--LELRRELYTSRRQLAAEQYRL-------------VEMARELAELNEAESDLEQDYQAAS---DHL 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1461 DKLKEELAQQGKdLDSLKSVLEEKENRIEKQeSELTAElkiQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKE 1540
Cdd:PRK04863   338 NLVQTALRQQEK-IERYQADLEELEERLEEQ-NEVVEE---ADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTR 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1541 vAWQLQQAeKVAFEK----------------------DSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKS------ 1592
Cdd:PRK04863   413 -AIQYQQA-VQALERakqlcglpdltadnaedwleefQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKiagevs 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1593 ---AILKSKEEELKELEERLNAEN----SCKLADLKKKAEQKigsikRELVRQMEEKEQQLKQDRENQVrHLEQKVQERE 1665
Cdd:PRK04863   491 rseAWDVARELLRRLREQRHLAEQlqqlRMRLSELEQRLRQQ-----QRAERLLAEFCKRLGKNLDDED-ELEQLQEELE 564

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 2024469763 1666 AKIESLEEkmkSVRDSTELEREMLQKIESTKAAVEQ 1701
Cdd:PRK04863   565 ARLESLSE---SVSEARERRMALRQQLEQLQARIQR 597
CCDC73 pfam15818
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ...
 887-1220 2.58e-03

Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.


Pssm-ID: 464893 [Multi-domain]  Cd Length: 1048  Bit Score: 43.01  E-value: 2.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  887 QYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEM 966
Cdd:pfam15818   25 QYEEQIGKIIVETQELKWQKETLQNQKETLAKQHKEAMAVFKKQLQMKMCALEEEKGKYQLATEIKEKEIEGLKETLKAL 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  967 Q---ETFKKKLAEQESKLK-----KELENKQLEFSQK-----ESEF-----NAKMLEMAHASSAGINDAVSKLESNQKEQ 1028
Cdd:pfam15818  105 QvskYSLQKKVSEMEQKLQlhllaKEDHHKQLNEIEKyyatiTGQFglvkeNHGKLEQNVQEAIQLNKRLSALNKKQESE 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1029 LESLAEAHKRELEEISRSwekKLNQQAEELQEKheMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETL 1108
Cdd:pfam15818  185 ICSLKKELKKVTSDLIKS---KVTCQYKMGEEN--INLTIKEQKFQELQERLNMELELNKKINEEITHIQEEKQDIIISF 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1109 KQLQEELKQslaQMSALSNSESGLKAQLQKlegdlSQSLKEKSGLQEQisrqkaieekdkariteladKLKTLEEKLQTL 1188
Cdd:pfam15818  260 QHMQQLLQQ---QTQANTEMEAELKALKEN-----NQTLERDNELQRE--------------------KVKENEEKFLNL 311

                          330       340       350
                   ....*....|....*....|....*....|..
gi 2024469763 1189 QSSHSKDRENYEKKIEAFQQQETEVKELVAQL 1220
Cdd:pfam15818  312 QNEHEKALGTWKKHVEELNGEINEIKNELSSL 343
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 274-480 2.63e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  274 EDSVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMkdlhmgekTKLITQLRDAKNL 353
Cdd:COG4942     51 KALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL--------LRALYRLGRQPPL 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  354 IEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEELKEQKEKFERAAfEELEKALGMAQRTEEARKKLQ 433
Cdd:COG4942    123 ALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL-AELEEERAALEALKAERQKLL 201

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024469763  434 TEMDEKIKAVEKANEE---ERVNLQQELTRVKQEVVEIMKKSSEDRVAEL 480
Cdd:COG4942    202 ARLEKELAELAAELAElqqEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1093-1378 2.63e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 2.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1093 EITRLKEE-QVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEgdlsqslkeKSGLQEQISRQKAIEEKDKARI 1171
Cdd:PRK05771    32 HIEDLKEElSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVS---------VKSLEELIKDVEEELEKIEKEI 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1172 TELADKLKTLEEKLQTLQSshskdrenyekkieafqqqetEVKELvaqldAYWKSAEVLLQtksnELIEKCNEKI--GIV 1249
Cdd:PRK05771   103 KELEEEISELENEIKELEQ---------------------EIERL-----EPWGNFDLDLS----LLLGFKYVSVfvGTV 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1250 TCKIADCERQATKVKEAVIIKmnksvqQLQEKDNVIksmrddiegLVTEKEQLQ------KEGGHQKQAATEKETcITQL 1323
Cdd:PRK05771   153 PEDKLEELKLESDVENVEYIS------TDKGYVYVV---------VVVLKELSDeveeelKKLGFERLELEEEGT-PSEL 216

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763 1324 RKELSENINAVTSLREDLqekESEISTLNKTINELNVRLESMVSlTEKEAAISLL 1378
Cdd:PRK05771   217 IREIKEELEEIEKERESL---LEELKELAKKYLEELLALYEYLE-IELERAEALS 267
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1486-1954 2.66e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1486 NRIEKQESELtAELKIQAARVAELEEHIAQKTSENDSLKEELKR-YHEQKDMEQKEVAWQLQQAEKVAFEKDSRLKEAEE 1564
Cdd:COG4717     71 KELKELEEEL-KEAEEKEEEYAELQEELEELEEELEELEAELEElREELEKLEKLLQLLPLYQELEALEAELAELPERLE 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1565 KVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLnaensckladlkkkaeqkigsikRELVRQMEEKEQ 1644
Cdd:COG4717    150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL-----------------------QDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1645 QLKQdRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREM-LQKIESTKAAVEQEKNEVIKSVQQ----------- 1712
Cdd:COG4717    207 RLAE-LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARlLLLIAAALLALLGLGGSLLSLILTiagvlflvlgl 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1713 -----THEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKK 1787
Cdd:COG4717    286 lallfLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1788 YSLLVDEHARCGGDLASSREELKAKEQKnlgmeniMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEvhkTEMEDRSL 1867
Cdd:COG4717    366 EELEQEIAALLAEAGVEDEEELRAALEQ-------AEEYQELKEELEELEEQLEELLGELEELLEALDE---EELEEELE 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1868 KYEENLKSLQQQLEERNDRLKALEEnaeekAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLR 1947
Cdd:COG4717    436 ELEEELEELEEELEELREELAELEA-----ELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYR 510


                   ....*..
gi 2024469763 1948 KEHQQEL 1954
Cdd:COG4717    511 EERLPPV 517
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1499-2122 3.00e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.03  E-value: 3.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1499 LKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQLQQAEKVAFEKDSR---LKEAEEKVLNLENEIGS 1575
Cdd:TIGR00618  199 LTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKqqlLKQLRARIEELRAQEAV 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1576 LKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQLKQDRENQVR 1655
Cdd:TIGR00618  279 LEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIR 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1656 HLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKN-KLLQK 1734
Cdd:TIGR00618  359 DAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQqELQQR 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1735 YESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGGDLASSREELKAKEQ 1814
Cdd:TIGR00618  439 YAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQ 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1815 KNLG-------MENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSL--KYEENLKSLQQQLEernD 1885
Cdd:TIGR00618  519 DIDNpgpltrrMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCdnRSKEDIPNLQNITV---R 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1886 RLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEM 1965
Cdd:TIGR00618  596 LQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1966 EQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESELIENHQIEtTQLHKKIAEKDDDLKRT 2045
Cdd:TIGR00618  676 ASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR-EDALNQSLKELMHQART 754

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763 2046 VKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQRMAEKDHRNSEnvtIAELQAQLAQKTTLVNDSKLKEQEFKEQ 2122
Cdd:TIGR00618  755 VLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHL---LKTLEAEIGQEIPSDEDILNLQCETLVQ 828
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1458-2084 3.18e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.89  E-value: 3.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1458 EELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQ------------------------------ESELTAELKIQAARVA 1507
Cdd:pfam10174  116 ENFRRLQSEHERQAKELFLLRKTLEEMELRIETQkqtlgardesikkllemlqskglpkksgeeDWERTRRIAEAEMQLG 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1508 ELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQlqqaeKVAFEKDSRLKEAEEKVLNLENEIGSLKAE----CEAK 1583
Cdd:pfam10174  196 HLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQ-----TVIEMKDTKISSLERNIRDLEDEVQMLKTNgllhTEDR 270

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1584 EREFDQMKsailkskeeelkeleerlnaensckladlkkkaeqkigsIKRELVRQMEEKEQQLKQDrenqVRHLEQKVQE 1663
Cdd:pfam10174  271 EEEIKQME---------------------------------------VYKSHSKFMKNKIDQLKQE----LSKKESELLA 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1664 REAKIESLEEKMKSVRDSTELEREMLQKIEStKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGI 1743
Cdd:pfam10174  308 LQTKLETLTNQNSDCKQHIEVLKESLTAKEQ-RAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLK 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1744 DSLLELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEqakkyslLVDEHARCGGDLASSREELKAKEQKnlgMENIM 1823
Cdd:pfam10174  387 DMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKS-------LQTDSSNTDTALTTLEEALSEKERI---IERLK 456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1824 GDFQKKMQEKDAVSHSLEQKVKELEDNLAKVnEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLE 1903
Cdd:pfam10174  457 EQREREDRERLEELESLKKENKDLKEKVSAL-QPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSK 535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1904 LQKLLGDMQNQQKDLQAKLEEAEREKQkLRKDVNSLQKDLRTLRKEHQQELDIvkkesLEEMEQKIRCEQEDIELKHSST 1983
Cdd:pfam10174  536 LENQLKKAHNAEEAVRTNPEINDRIRL-LEQEVARYKEESGKAQAEVERLLGI-----LREVENEKNDKDKKIAELESLT 609

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1984 LKQlMREFNTQLAQKEMELETAVKETiskAQEVESELIENHQIETTQLHKKIAEKDDDLKRTvKKYEEILEAREEEMTTK 2063
Cdd:pfam10174  610 LRQ-MKEQNKKVANIKHGQQEMKKKG---AQLLEEARRREDNLADNSQQLQLEELMGALEKT-RQELDATKARLSSTQQS 684

                          650       660
                   ....*....|....*....|.
gi 2024469763 2064 VHELQTQLEELQKEYKQRMAE 2084
Cdd:pfam10174  685 LAEKDGHLTNLRAERRKQLEE 705
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 688-918 3.26e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  688 LSSELSEALKVRQDLEQELSELKSKVGEAKQEFEgKLEAERNQHKEEveimLKEHEISIQDVEKVLKE---ELNQMKQSL 764
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELA-ALKKEEKALLKQ----LAALERRIAALARRIRAleqELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  765 EEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAK--QYEEELAKLQQKLMDLKGEKLqlsEQL 842
Cdd:COG4942     86 AELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRrlQYLKYLAPARREQAEELRADL---AEL 162

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763  843 VRTECQLNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQ---YESQLKDLQEEADKAKQTLTERENDIEHVKK 918
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKElaeLAAELAELQQEAEELEALIARLEAEAAAAAE 241
YidC COG1422
Archaeal YidC/Oxa1-related membrane protein, DUF106 family [Cell wall/membrane/envelope ...
 490-531 3.53e-03

Archaeal YidC/Oxa1-related membrane protein, DUF106 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441032  Cd Length: 198  Bit Score: 41.04  E-value: 3.53e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 2024469763  490 TKDQELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQ 531
Cdd:COG1422     63 LMDWEKMGKYQERMKAFQKERREAQERGDDEALKKLQEEQME 104
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
649-873 3.68e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  649 EQEIDTILKEKETVfrTHIEEMNEKtLEKLDVKQTELETLSSELS--EALKVRQDLEQELSELKSKVGEAKQEFEgKLEA 726
Cdd:COG4913    241 HEALEDAREQIELL--EPIRELAER-YAAARERLAELEYLRAALRlwFAQRRLELLEAELEELRAELARLEAELE-RLEA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  727 ERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELvqvsarlmeasLSQ 806
Cdd:COG4913    317 RLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEF-----------AAL 385

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024469763  807 QNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELELYISQVHELKQQLQEQ 873
Cdd:COG4913    386 RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1804-1994 3.71e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1804 SSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKvkelEDNLAKVNEVHKTEMEDRSLKYE-ENLKSLQQQLEE 1882
Cdd:COG4913    607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQER----REALQRLAEYSWDEIDVASAEREiAELEAELERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1883 RNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQEL--DIVKKE 1960
Cdd:COG4913    683 SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfaAALGDA 762

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2024469763 1961 SLEEMEQKIRCEQEDIELKHSSTLKQL---MREFNTQ 1994
Cdd:COG4913    763 VERELRENLEERIDALRARLNRAEEELeraMRAFNRE 799
PRK11281 PRK11281
mechanosensitive channel MscK;
850-1220 3.73e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  850 NEVKNELELYISQ-VHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEE----- 923
Cdd:PRK11281    39 ADVQAQLDALNKQkLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEEtretl 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  924 ----MEELKQKLLATEERISTLQ---GDYENKLKRQENKMEK----MKQKSKEMQE---------TFKKKL-AEQESKLK 982
Cdd:PRK11281   119 stlsLRQLESRLAQTLDQLQNAQndlAEYNSQLVSLQTQPERaqaaLYANSQRLQQirnllkggkVGGKALrPSQRVLLQ 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  983 KELE--NKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEqLESLAEAHKRELEEisrswekklnQQAEELQE 1060
Cdd:PRK11281   199 AEQAllNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQL-LQEAINSKRLTLSE----------KTVQEAQS 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1061 khemelQEKEQELGD---LKEKLATfsaekegsRTEITRLKEEQVKRNETLKQLQEELKQslaQMSALSNSESGLKAQLQ 1137
Cdd:PRK11281   268 ------QDEAARIQAnplVAQELEI--------NLQLSQRLLKATEKLNTLTQQNLRVKN---WLDRLTQSERNIKEQIS 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1138 KLEGDL---------SQSL---KEKSGLQEQIS--RQKAIEekdkarITELADKLKTLEEKLQTLQSSHSKDRENYEKKi 1203
Cdd:PRK11281   331 VLKGSLllsrilyqqQQALpsaDLIEGLADRIAdlRLEQFE------INQQRDALFQPDAYIDKLEAGHKSEVTDEVRD- 403

                          410
                   ....*....|....*..
gi 2024469763 1204 eAFQQQETEVKELVAQL 1220
Cdd:PRK11281   404 -ALLQLLDERRELLDQL 419
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 810-1993 3.80e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.73  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  810 SNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNELeLYISQVH-ELKQQLQEQSDEN--TQKAMSLTQ 886
Cdd:TIGR01612  549 SYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEI-IYINKLKlELKEKIKNISDKNeyIKKAIDLKK 627

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  887 QYESQLKDLQEEADKAKQTLTErendieHVKKvqneemeelKQKLLATEEriSTLQGDYENKLKRQENKMEKMKQKSKEM 966
Cdd:TIGR01612  628 IIENNNAYIDELAKISPYQVPE------HLKN---------KDKIYSTIK--SELSKIYEDDIDALYNELSSIVKENAID 690

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  967 QETFKKKLAEQESKLKKELENKQlefsqkesefnakmlemaHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISrs 1046
Cdd:TIGR01612  691 NTEDKAKLDDLKSKIDKEYDKIQ------------------NMETATVELHLSNIENKKNELLDIIVEIKKHIHGEIN-- 750

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1047 weKKLNQQAEELQEKhEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALS 1126
Cdd:TIGR01612  751 --KDLNKILEDFKNK-EKELSNKINDYAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKE 827

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1127 NSESGLKAQLQKLEGDLSQSLKEKSGLQeqiSRQKAIEEKDKARITELADKLKT--LEEKLQTLQSSHSKDRENYEKKIE 1204
Cdd:TIGR01612  828 DEIFKIINEMKFMKDDFLNKVDKFINFE---NNCKEKIDSEHEQFAELTNKIKAeiSDDKLNDYEKKFNDSKSLINEINK 904

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1205 AFQQQETEVKELvAQLDAYWKSAEVLLQT------KSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNK----- 1273
Cdd:TIGR01612  905 SIEEEYQNINTL-KKVDEYIKICENTKESiekfhnKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINEldkaf 983

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1274 ---SVQQLQEKDN-VIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKetcITQLRKELSENINAV-----TSLREDLQEK 1344
Cdd:TIGR01612  984 kdaSLNDYEAKNNeLIKYFNDLKANLGKNKENMLYHQFDEKEKATND---IEQKIEDANKNIPNIeiaihTSIYNIIDEI 1060

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1345 ESEI----STLNKTI-NELNVRLESMVSLTEKEAAISLlSTQHQEERLQLINQVQELSSSVELLRQekasaleQVDHCTA 1419
Cdd:TIGR01612 1061 EKEIgkniELLNKEIlEEAEINITNFNEIKEKLKHYNF-DDFGKEENIKYADEINKIKDDIKNLDQ-------KIDHHIK 1132

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1420 KLSEWKTKAQ----------------TRFTQNHETIKDLQSKLEVSNTQATKKG---EELDKLKEELAQQGKDLDSLKSV 1480
Cdd:TIGR01612 1133 ALEEIKKKSEnyideikaqindledvADKAISNDDPEEIEKKIENIVTKIDKKKniyDEIKKLLNEIAEIEKDKTSLEEV 1212

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1481 ---------------LEEKENRIEKQESELTAELKI--QAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAW 1543
Cdd:TIGR01612 1213 kginlsygknlgklfLEKIDEEKKKSEHMIKAMEAYieDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHII 1292

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1544 QLQQAEKVAFEKDSRLKEAEEkvLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELkeleerlNAENSCKLADLKKk 1623
Cdd:TIGR01612 1293 SKKHDENISDIREKSLKIIED--FSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIA-------NIYNILKLNKIKK- 1362

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1624 aeqkIGSIKRELVRQMEEKEQQLKQDRENQvRHLEQKVQErEAKIESLEEKMKSVRDSTELErEMLQKIESTKAAVEQE- 1702
Cdd:TIGR01612 1363 ----IIDEVKEYTKEIEENNKNIKDELDKS-EKLIKKIKD-DINLEECKSKIESTLDDKDID-ECIKKIKELKNHILSEe 1435

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1703 -----------------------------KNEVIKSVQQT-----HEEKINKLqKDLIEKNKLLQKYESEQREGIDSLLE 1748
Cdd:TIGR01612 1436 snidtyfknadennenvlllfkniemadnKSQHILKIKKDnatndHDFNINEL-KEHIDKSKGCKDEADKNAKAIEKNKE 1514

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1749 L--QSKQE--ELLKKLECAEKRHREEQSV--TEGLREELEEQAKKYSL-----------LVDEHARCGGDLASSREELKA 1811
Cdd:TIGR01612 1515 LfeQYKKDvtELLNKYSALAIKNKFAKTKkdSEIIIKEIKDAHKKFILeaekseqkikeIKKEKFRIEDDAAKNDKSNKA 1594

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1812 KEQKNLGMENIMGDFQKKMQEKDAVSHSLeqkvKELEDNLAKVNEVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALE 1891
Cdd:TIGR01612 1595 AIDIQLSLENFENKFLKISDIKKKINDCL----KETESIEKKISSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIE 1670

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1892 ENAEEkaksglelqkllgdmqnqqkdlqakLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRc 1971
Cdd:TIGR01612 1671 DKKKE-------------------------LDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKELIE- 1724

                         1290      1300
                   ....*....|....*....|..
gi 2024469763 1972 eqedielkhsSTLKQLMREFNT 1993
Cdd:TIGR01612 1725 ----------PTIENLISSFNT 1736
COG5022 COG5022
Myosin heavy chain [General function prediction only];
502-1196 4.13e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.37  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  502 QEREFQEKMKAALEKNQSECLKTLQEQEQQESLALEELELQKKAIQsecdKKLEEMHQEVEtFKTRILELESSLAkcsqd 581
Cdd:COG5022    783 LRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSYLACIIKLQKTIKR----EKKLRETEEVE-FSLKAEVLIQKFG----- 852

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  582 dkkRSEELSTLMDSEKKQhnkevsDIVEKHKEELENVKQQQEKLwteklqilqQQHVIEIEKMREKQEQEIDTILKEKET 661
Cdd:COG5022    853 ---RSLKAKKRFSLLKKE------TIYLQSAQRVELAERQLQEL---------KIDVKSISSLKLVNLELESEIIELKKS 914

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  662 VFRTHIEEMNEKTLEKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFE------GKLEAERNQHKEEV 735
Cdd:COG5022    915 LSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEdllkksTILVREGNKANSEL 994

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  736 EI------MLKEHEISIQDVEKVLKEE--LNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQ 807
Cdd:COG5022    995 KNfkkelaELSKQYGALQESTKQLKELpvEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRE 1074

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  808 NTSNEQAKQYEEELAKlqQKLMDLKGEKLQLSEQlvrtecqlNEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQ 887
Cdd:COG5022   1075 NSLLDDKQLYQLESTE--NLLKTINVKDLEVTNR--------NLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEP 1144

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  888 YESQLKDLQEEADKAKQTLTEREndiEHVKKVQNEEMEELKQKLLATEERISTLQgdyeNKLKRQENKMEKMKQKSKEMQ 967
Cdd:COG5022   1145 VFQKLSVLQLELDGLFWEANLEA---LPSPPPFAALSEKRLYQSALYDEKSKLSS----SEVNDLKNELIALFSKIFSGW 1217

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  968 ETFKKKL--------AEQESKLKKELENKQLEFSQKESEFNAKMLEMAHA-----SSAGINDAVSKLESNQKEQLESLAE 1034
Cdd:COG5022   1218 PRGDKLKklisegwvPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSidnllSSYKLEEEVLPATINSLLQYINVGL 1297

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1035 AHKRELEEISRSWE--KKLNQQAEELQEKhemelqEKEQELGDLKEKLatfsaEKEGSRTEITRLKEEQVKRNETLKQLQ 1112
Cdd:COG5022   1298 FNALRTKASSLRWKsaTEVNYNSEELDDW------CREFEISDVDEEL-----EELIQAVKVLQLLKDDLNKLDELLDAC 1366

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1113 EELK----QSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADK--LKTLEEKLQ 1186
Cdd:COG5022   1367 YSLNpaeiQNLKSRYDPADKENNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFSEEKSLISLDrnSIYKEEVLS 1446

                          730
                   ....*....|
gi 2024469763 1187 TLQSSHSKDR 1196
Cdd:COG5022   1447 SLSALLTKEK 1456
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1048-1192 4.18e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.54  E-value: 4.18e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  1048 EKKLNQQAEELQEKHEmELQEKEQELGDLKEKLatfSAEKEGSRTEITRLK----EEQVKRNETLKQLQEELKQSLAQMS 1123
Cdd:smart00787  146 KEGLDENLEGLKEDYK-LLMKELELLNSIKPKL---RDRKDALEEELRQLKqledELEDCDPTELDRAKEKLKKLLQEIM 221

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763  1124 ALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARItelADKLKTLEEKLQTLQSSH 1192
Cdd:smart00787  222 IKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFT---FKEIEKLKEQLKLLQSLT 287
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1337-1532 4.33e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1337 LREDLQEKESEistLNKTINELNVRLESM-VSLTEKEAAISLLSTQH-----QEERLQLINQVQELSSSVELLRQEKASA 1410
Cdd:COG3206    162 LEQNLELRREE---ARKALEFLEEQLPELrKELEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1411 LEQVDHCTAKLSEWKTKAQT-----RFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQqgkdldslksVLEEKE 1485
Cdd:COG3206    239 EARLAALRAQLGSGPDALPEllqspVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAA----------LRAQLQ 308

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2024469763 1486 NRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHE 1532
Cdd:COG3206    309 QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1643-1973 5.04e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 5.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1643 EQQLKQDRENqVRHLEQKVQEREAKIESLEEKM----KSVRDSTELEREMLQKIESTKAAVEQEKNEVIKSVQqtheEKI 1718
Cdd:pfam12128  229 DIQAIAGIMK-IRPEFTKLQQEFNTLESAELRLshlhFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWK----EKR 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1719 NKLQKDLIEKNKLLQKYESEqregidslLELQSKQEELLKKlECAEKRHrEEQSVTEGLREELEEQAKKYSLLVDEHARC 1798
Cdd:pfam12128  304 DELNGELSAADAAVAKDRSE--------LEALEDQHGAFLD-ADIETAA-ADQEQLPSWQSELENLEERLKALTGKHQDV 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1799 ggDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSLEQKVKELEDNLAKVNEVHKTEMEDRSLKYEENLkslqq 1878
Cdd:pfam12128  374 --TAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRL----- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1879 qlEERNDRLKALEENAEEKAksglelqkllgdmqnQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVK 1958
Cdd:pfam12128  447 --GELKLRLNQATATPELLL---------------QLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALR 509

                          330
                   ....*....|....*
gi 2024469763 1959 KESLEEMEQKIRCEQ 1973
Cdd:pfam12128  510 QASRRLEERQSALDE 524
Abraxas_1 cd23523
BRCA1-A complex subunit Abraxas 1; BRCA1-A complex subunit Abraxas 1, also known as ABRA1, ...
 1911-1984 5.11e-03

BRCA1-A complex subunit Abraxas 1; BRCA1-A complex subunit Abraxas 1, also known as ABRA1, FAM175A, and CCDC98, is involved in DNA damage response and double-strand break (DSB) repair and acts as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex consists of Abraxas 1, BRCC36, BRE, MERIT40, and RAP80, and specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase (DUB) activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX; its DUB is BRCC36, which associates with pseudo-DUB protein Abraxas 1 which lacks the essential Zn2+-coordinating residues required for DUB catalytic function. BRCA1-A opposes homologous recombination (HR) by suppressing resection. It has been shown for BIR (break-induced replication), an HR-subtype that involves extensive DNA resection and mutagenic DNA synthesis; that Abraxas 1 inhibits DNA end resection through regulating the levels of SLX4/MUS81 chromatin loading at DSBs in response to Topoisomerase I (TOP1) inhibitor-induced DNA damage. Familial mutations in the BRCA1-A proteins Abraxas 1 and RAP80 predispose carriers to early-onset breast cancer, analogous to mutations in BRCA1 and BRCA2. BRCA1-A requires the tandem ubiquitin (UIM2)- and SUMO-interacting motifs (SIM) in RAP80 and the BRCC36 DUB to function in DNA repair. BRCA1-A recruits BRCA1 by binding its BRCT domains upon phosphorylation of a motif near the C-terminus of Abraxas 1. BRCA1 binding to BRCA1-A sequesters the HR activator BRCA1 about 2-10 kb distal from DNA break sites, which is posited to limit HR. It is currently unclear how BRCA1-A is functionalized and targeted by RAP80 and Abraxas 1 and how BRCA1 is inhibited when bound to the complex. BRCC36 in BRCA1-A is activated by assembly due to interaction between Glu30 of BRCC36 and Asn170 in Abraxas 1 which structures the activation loop and positions the catalytic Glu33.


Pssm-ID: 467803  Cd Length: 379  Bit Score: 41.43  E-value: 5.11e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024469763 1911 MQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTlRKEHQQELDIVKKESLEEMEQKIRCEQ-----EDIELKHSSTL 1984
Cdd:cd23523    221 LQEELKKICKKVEESERSVEKLLKDVNRLKEEIAK-RKRAQTQATAEKSVPEEPEENVLLCQAlrtffPNSELLHSCTL 298
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
612-826 5.65e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 5.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  612 KEELENVKQQQEKLWTEKLQILQQQHVIEieKMREKQEQEIDTILKEKEtvfrthIEEmNEKTLEKLDVKQTELETLSSE 691
Cdd:COG4913    623 EEELAEAEERLEALEAELDALQERREALQ--RLAEYSWDEIDVASAERE------IAE-LEAELERLDASSDDLAALEEQ 693

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  692 LSEALKVRQDLEQELSELKSKvgeakqefEGKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKEELNQMKQSLEEKERLL 771
Cdd:COG4913    694 LEELEAELEELEEELDELKGE--------IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER 765

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024469763  772 EEAKTREQE---LKESAQRSEAELVqvsaRLMEA-------SLSQQNTSNEQAKQYEEELAKLQQ 826
Cdd:COG4913    766 ELRENLEERidaLRARLNRAEEELE----RAMRAfnrewpaETADLDADLESLPEYLALLDRLEE 826
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 446-789 5.67e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 41.76  E-value: 5.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  446 ANEEERVNLQQELTRVKQEVVEIMKKSSEDRVAEL----EKLHKEematKDQELNERLQAQEreFQEKmkaaLEKNQSEC 521
Cdd:PLN03229   426 AVKTPVRELEGEVEKLKEQILKAKESSSKPSELALnemiEKLKKE----IDLEYTEAVIAMG--LQER----LENLREEF 495

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  522 LKTlqeqEQQESLALEELELQKKAIQSECDKKLEEMhQEVETFKTRILEL-ESSLAKCSQDDKKRSEELstlmdseKKQH 600
Cdd:PLN03229   496 SKA----NSQDQLMHPVLMEKIEKLKDEFNKRLSRA-PNYLSLKYKLDMLnEFSRAKALSEKKSKAEKL-------KAEI 563

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  601 NKEVSDIVEKH--KEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQEIDTILK----EKETVFRTHIEEMNEKT 674
Cdd:PLN03229   564 NKKFKEVMDRPeiKEKMEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELELAGVLKsmglEVIGVTKKNKDTAEQTP 643

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  675 LEKLDVKQTEL-ETLSSELSEALKVrQDLEQELSELKSKVGEAKQ----EFEGKLEAERNQHKEEVEIMLKEHEisIQDV 749
Cdd:PLN03229   644 PPNLQEKIESLnEEINKKIERVIRS-SDLKSKIELLKLEVAKASKtpdvTEKEKIEALEQQIKQKIAEALNSSE--LKEK 720

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 2024469763  750 EKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSE 789
Cdd:PLN03229   721 FEELEAELAAARETAAESNGSLKNDDDKEEDSKEDGSRVE 760
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
927-1140 5.78e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 5.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  927 LKQKLLATEERISTLQG---DYENKLKRQENKMEKMKQKSKEMQ-ETFKKKLAEQESKLKKELENKQLEFSQKESEFNAK 1002
Cdd:COG3206    166 LELRREEARKALEFLEEqlpELRKELEEAEAALEEFRQKNGLVDlSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1003 MLEMAHASSAGINDAVSKLESNQKEQLESLaeahkreleeisrswEKKLNQQAEELQEKHEmELQEKEQELGDLKEKLat 1082
Cdd:COG3206    246 RAQLGSGPDALPELLQSPVIQQLRAQLAEL---------------EAELAELSARYTPNHP-DVIALRAQIAALRAQL-- 307

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024469763 1083 fsaekegsRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLE 1140
Cdd:COG3206    308 --------QQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1541-1776 5.92e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1541 VAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENscKLADL 1620
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA--ELAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1621 kkkaEQKIGSIKRELVRQMEEKEQQL----KQDRENQVRHL--EQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIES 1694
Cdd:COG4942     89 ----EKEIAELRAELEAQKEELAELLralyRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1695 TKAAVEQEKNEvIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECAEKRHREEQSVT 1774
Cdd:COG4942    165 LRAELEAERAE-LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                   ..
gi 2024469763 1775 EG 1776
Cdd:COG4942    244 PA 245
PRK12704 PRK12704
phosphodiesterase; Provisional
 862-984 6.40e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 6.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  862 QVHELKQQLQEQSDENTQKAMSL---TQQYESQLKDLQEEADKAKQTLTERENDIEHVKK---VQNEEMEELKQKLLATE 935
Cdd:PRK12704    65 EIHKLRNEFEKELRERRNELQKLekrLLQKEENLDRKLELLEKREEELEKKEKELEQKQQeleKKEEELEELIEEQLQEL 144

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024469763  936 ERISTLQGDyENKlkrqENKMEKMKQKSK-EMQETFKKKLAEQESKLKKE 984
Cdd:PRK12704   145 ERISGLTAE-EAK----EILLEKVEEEARhEAAVLIKEIEEEAKEEADKK 189
PRK11281 PRK11281
mechanosensitive channel MscK;
775-1032 6.51e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 6.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  775 KTREQELKESAQRSEAELVQVSARL-----MEASLSQQNTSNEQAKQYEEELAKLQQKLMDLKGEKLQLSEQLVRTECQL 849
Cdd:PRK11281    79 KEETEQLKQQLAQAPAKLRQAQAELealkdDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQP 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  850 NEVKNELELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKvQNEEMEELKQ 929
Cdd:PRK11281   159 ERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQK-QRDYLTARIQ 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  930 KLlatEERISTLQGDYENK-LKRQENKMEKMkQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAH 1008
Cdd:PRK11281   238 RL---EHQLQLLQEAINSKrLTLSEKTVQEA-QSQDEAARIQANPLVAQELEINLQLSQRLLKATEKLNTLTQQNLRVKN 313

                          250       260
                   ....*....|....*....|....
gi 2024469763 1009 assagINDAVSKLESNQKEQLESL 1032
Cdd:PRK11281   314 -----WLDRLTQSERNIKEQISVL 332
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1450-1946 6.96e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 6.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1450 NTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTaELKIQAARVAELEEHIAQKTSENDSLKEELKR 1529
Cdd:TIGR04523  144 LTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNID-KIKNKLLKLELLLSNLKKKIQKNKSLESQISE 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1530 YHEQkdmeQKEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEerl 1609
Cdd:TIGR04523  223 LKKQ----NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKS--- 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1610 naenscKLADLKKKAEQKIGSIKRELVRQMEEKEQQLkqdrENQVRHLEQKVQEREAKIESLE-EKMKSVRDSTELEREM 1688
Cdd:TIGR04523  296 ------EISDLNNQKEQDWNKELKSELKNQEKKLEEI----QNQISQNNKIISQLNEQISQLKkELTNSESENSEKQREL 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1689 LQK---IESTKAAVEQEKNEVIKSVQQTHE-----EKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKL 1760
Cdd:TIGR04523  366 EEKqneIEKLKKENQSYKQEIKNLESQINDleskiQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1761 ECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARcggDLASSREELKAKEQKNLGMENIMGDFQKKMQEKDAVSHSL 1840
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQ---NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1841 EQKVKELEDNLAKVN-EVHKTEMEDRSLKYEENLKSLQQQLEERNDRLKALEENAEEKAKSGLELQKLLGDMQNQQKDLQ 1919
Cdd:TIGR04523  523 KEKIEKLESEKKEKEsKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI 602

                          490       500
                   ....*....|....*....|....*..
gi 2024469763 1920 AKLEEAEREKQKLRKDVNSLQKDLRTL 1946
Cdd:TIGR04523  603 KEIEEKEKKISSLEKELEKAKKENEKL 629
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
641-783 6.97e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 6.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  641 IEKMREKQEQEIDTILKEKETVFRTHIEEMNEKtLEKLDVKQTELETLSSELSEALKvrqDLEQELSELKSKVGEAKQEF 720
Cdd:COG2433    382 LEELIEKELPEEEPEAEREKEHEERELTEEEEE-IRRLEEQVERLEAEVEELEAELE---EKDERIERLERELSEARSEE 457

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024469763  721 EGKLEAERnqhkeEVEIMLKEheisIQDVEKVLKEELNQMKQSleekerlleeaKTREQELKE 783
Cdd:COG2433    458 RREIRKDR-----EISRLDRE----IERLERELEEERERIEEL-----------KRKLERLKE 500
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1447-1553 7.21e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 7.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1447 EVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELtAELKIQAARVAELEEHIAQKTSENDSLKEE 1526
Cdd:COG2433    402 EHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLEREL-SEARSEERREIRKDREISRLDREIERLERE 480

                           90       100
                   ....*....|....*....|....*..
gi 2024469763 1527 LkryhEQKDMEQKEVAWQLQQAEKVAF 1553
Cdd:COG2433    481 L----EEERERIEELKRKLERLKELWK 503
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1452-1789 7.28e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 7.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1452 QATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRiekqESELTAELKIQAARVAELEEHIAQKtsendslkEELKRYh 1531
Cdd:COG3096    286 RALELRRELFGARRQLAEEQYRLVEMARELEELSAR----ESDLEQDYQAASDHLNLVQTALRQQ--------EKIERY- 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1532 eQKDMEqkEVAWQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFD-QMKSAILKSKEEELKEleerlN 1610
Cdd:COG3096    353 -QEDLE--ELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDvQQTRAIQYQQAVQALE-----K 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1611 AENSCKLADLKKKAEQkigsikrELVRQMEEKEQQLKQdrenQVRHLEQKVQEREAKIESLEEKMKSVR---------DS 1681
Cdd:COG3096    425 ARALCGLPDLTPENAE-------DYLAAFRAKEQQATE----EVLELEQKLSVADAARRQFEKAYELVCkiageversQA 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1682 TELEREMLQKIESTKAAVEQEknEVIKSvQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLE 1761
Cdd:COG3096    494 WQTARELLRRYRSQQALAQRL--QQLRA-QLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELE 570

                          330       340
                   ....*....|....*....|....*...
gi 2024469763 1762 CAEKRHREEQSVTEGLREELEEQAKKYS 1789
Cdd:COG3096    571 EQAAEAVEQRSELRQQLEQLRARIKELA 598
46 PHA02562
endonuclease subunit; Provisional
 550-755 7.75e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 7.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  550 CDKKLEEMHQEVETFKTRILELESSLAKCSQDDKKRSEELSTLMDSEKKQhNKEVSDIVEKHKEELENVKQQQEKLWTEK 629
Cdd:PHA02562   186 LDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAE-IEELTDELLNLVMDIEDPSAALNKLNTAA 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  630 LQI-LQQQHVIEIEKMREKQE------QEIDTiLKEKETVFRTHIEEMNEKtLEKLDVKQTELETLSSELSEALKVRQDL 702
Cdd:PHA02562   265 AKIkSKIEQFQKVIKMYEKGGvcptctQQISE-GPDRITKIKDKLKELQHS-LEKLDTAIDELEEIMDEFNEQSKKLLEL 342

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  703 EQELSELK-------SKVGEAKQEFEgKLEAERNQHKEEVEIMLKEHEISIQDVEKVLKE 755
Cdd:PHA02562   343 KNKISTNKqslitlvDKAKKVKAAIE-ELQAEFVDNAEELAKLQDELDKIVKTKSELVKE 401
PRK12704 PRK12704
phosphodiesterase; Provisional
 1420-1529 8.06e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 8.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1420 KLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEKQESELTael 1499
Cdd:PRK12704    58 ALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELE--- 134

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 2024469763 1500 KIQAARVAELeEHIAQKTSEN------DSLKEELKR 1529
Cdd:PRK12704   135 ELIEEQLQEL-ERISGLTAEEakeillEKVEEEARH 169
PRK01156 PRK01156
chromosome segregation protein; Provisional
 676-1189 8.13e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.43  E-value: 8.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  676 EKLDVKQTELETLSSELSEALKVRQDLEQELSELKSKVGEAKQEFE---------GKLEAERNQHKEEVEI------MLK 740
Cdd:PRK01156   190 EKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNnlksalnelSSLEDMKNRYESEIKTaesdlsMEL 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  741 EHEISIQDVEKVLKEELNQMKQSLEEKERLLEEAKTREQELKESAQRSEAELVQVSARLMEASLSQQNTSNEQAKQYEEE 820
Cdd:PRK01156   270 EKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYD 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  821 laKLQQKLMDLKGEKLQLSEQLVRTECQLNEVKNE------LELYISQVHELKQQLQEQSDENTQKAMSLTQQYESQLKD 894
Cdd:PRK01156   350 --DLNNQILELEGYEMDYNSYLKSIESLKKKIEEYsknierMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSS 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  895 LQEEADKAKQTLTEREND---------------------IEHVKKVQNEEMEELKQKLLATEERIStlqgDYENKLKRQE 953
Cdd:PRK01156   428 LNQRIRALRENLDELSRNmemlngqsvcpvcgttlgeekSNHIINHYNEKKSRLEEKIREIEIEVK----DIDEKIVDLK 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  954 NKMEKMKQKSKEMQETFKKKLAEQESKLKK------ELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKE 1027
Cdd:PRK01156   504 KRKEYLESEEINKSINEYNKIESARADLEDikikinELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIE 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1028 QLESLAEAHKRELEEIsrswEKKLNQ---QAEELQEKHEMELQEKEQELGDLKEKLatfsaekegsrteitRLKEEQVKR 1104
Cdd:PRK01156   584 TNRSRSNEIKKQLNDL----ESRLQEieiGFPDDKSYIDKSIREIENEANNLNNKY---------------NEIQENKIL 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1105 NETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEK 1184
Cdd:PRK01156   645 IEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINET 724


                   ....*
gi 2024469763 1185 LQTLQ 1189
Cdd:PRK01156   725 LESMK 729
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 921-1660 8.53e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.25  E-value: 8.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  921 NEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKK-KLAEQESKLKKELENKQLEFSQKESEF 999
Cdd:pfam05483   73 SEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQElQFENEKVSLKLEEEIQENKDLIKENNA 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1000 NAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKrELEEISRSWEkKLNQQAEELQEKHEMELQEKEQELGDLKEK 1079
Cdd:pfam05483  153 TRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNN-NIEKMILAFE-ELRVQAENARLEMHFKLKEDHEKIQHLEEE 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1080 LATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKE-KSGLQEQIS 1158
Cdd:pfam05483  231 YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDiKMSLQRSMS 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1159 RQkaieekdkariteladklKTLEEKLQTLQSSHSKDRENYEKKIEAFQQQETEVKELVAQLDAYWKSAEVLLQTKSNEL 1238
Cdd:pfam05483  311 TQ------------------KALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRL 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1239 iEKCNEKIGIVTCKIadcERQATKVKEAVIIKMNKSVQQLQekdnvIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKET 1318
Cdd:pfam05483  373 -EKNEDQLKIITMEL---QKKSSELEEMTKFKNNKEVELEE-----LKKILAEDEKLLDEKKQFEKIAEELKGKEQELIF 443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1319 CITQLRKELSENINAVTSLREDLQEKESEISTLNktiNELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSS 1398
Cdd:pfam05483  444 LLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLK---TELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQE 520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1399 SVELLRQEKASALEQVDHCTAKLSEWKTKAQTRFTQNHETIKDLQSKLEVSNTQATKKGEELDKLKEELAQQGKDLDSLK 1478
Cdd:pfam05483  521 DIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLK 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1479 SVLEEKENRIEKQESELTAELKIQAARVAELEEHIAQKTSENDSLKEELKRYHEQKDMEQKEVAWQ-------LQQAEKV 1551
Cdd:pfam05483  601 KQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKkiseeklLEEVEKA 680

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1552 AFEKDSRLKEAEEKVLNLENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEqkIGSI 1631
Cdd:pfam05483  681 KAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAE--LLSL 758

                          730       740
                   ....*....|....*....|....*....
gi 2024469763 1632 KRELVRQMEEKEQQLKQDRENQVRHLEQK 1660
Cdd:pfam05483  759 KKQLEIEKEEKEKLKMEAKENTAILKDKK 787
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 883-1035 8.94e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 40.95  E-value: 8.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  883 SLTQQYESQLKDLQEEADKAKQTlterendiehvKKVQNEEMEELKQKLLATEERISTLQGDYENKLKRQENKMEKMKQ- 961
Cdd:PRK09510    59 AVVEQYNRQQQQQKSAKRAEEQR-----------KKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQa 127

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024469763  962 KSKEMQETFKKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEA 1035
Cdd:PRK09510   128 ALKQKQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKK 201
PRK12705 PRK12705
hypothetical protein; Provisional
 1048-1213 9.01e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 40.85  E-value: 9.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1048 EKKLNQQAEELQEKHEMELQE-KEQELGDLKEKLATFSAEKEGSRTEITRLkeeqVKRNETLKQLQEELKQSLAQMSALS 1126
Cdd:PRK12705    36 ERILQEAQKEAEEKLEAALLEaKELLLRERNQQRQEARREREELQREEERL----VQKEEQLDARAEKLDNLENQLEERE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1127 NSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKDKARITELADKLKTLEEKLQTLQsshskDRENYEKKIEAF 1206
Cdd:PRK12705   112 KALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEA-----ERKAQNILAQAM 186


                   ....*..
gi 2024469763 1207 QQQETEV 1213
Cdd:PRK12705   187 QRIASET 193
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1904-2139 9.07e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.26  E-value: 9.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1904 LQKLLGDMQNQQKDLQAKLEEA----EREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQKIRCEQEDIELK 1979
Cdd:pfam15921   76 IERVLEEYSHQVKDLQRRLNESnelhEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELE 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1980 HSSTLKQ-LMREFNTQLAQkemeLETAVKETISKAQEVESELIENHQIETtqlhKKIAEKDD-------DLKRTVKKYEE 2051
Cdd:pfam15921  156 AAKCLKEdMLEDSNTQIEQ----LRKMMLSHEGVLQEIRSILVDFEEASG----KKIYEHDSmstmhfrSLGSAISKILR 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 2052 ILEAREEEMTTKVHELQTQLEELQKEYKQRMA--EKDHRNSENVTIAELQAQLAQKTTLVNDSKLKEQEFKEQIHVLEDR 2129
Cdd:pfam15921  228 ELDTEISYLKGRIFPVEDQLEALKSESQNKIEllLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQ 307

                          250
                   ....*....|
gi 2024469763 2130 LKNyEKKMYV 2139
Cdd:pfam15921  308 ARN-QNSMYM 316
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 212-477 9.18e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.07  E-value: 9.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  212 EEKDQLISVLQ----TQVSLLKQRLQNGQIGIELPDpnnqsepqvQSQTKEINA--ENIVEPGSNEGNEDSVKTLETLNQ 285
Cdd:PRK05771    16 SYKDEVLEALHelgvVHIEDLKEELSNERLRKLRSL---------LTKLSEALDklRSYLPKLNPLREEKKKVSVKSLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  286 RVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEErlqeLEKMKDLHMGEK----TKLITQL-----RDAKNLIEQ 356
Cdd:PRK05771    87 LIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIER----LEPWGNFDLDLSlllgFKYVSVFvgtvpEDKLEELKL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  357 LEQDKGMVIAETKRQMH-----------------------------------ETLEMKEEEVAQLRARIKQITTQGEELK 401
Cdd:PRK05771   163 ESDVENVEYISTDKGYVyvvvvvlkelsdeveeelkklgferleleeegtpsELIREIKEELEEIEKERESLLEELKELA 242

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024469763  402 EQKEKFERAAFEELEkalgmaQRTEEARKKLQTEMDEKIKAVEKANEEERVnlqqeltrvkQEVVEIMKKSSEDRV 477
Cdd:PRK05771   243 KKYLEELLALYEYLE------IELERAEALSKFLKTDKTFAIEGWVPEDRV----------KKLKELIDKATGGSA 302
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1877-2017 9.31e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.35  E-value: 9.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763 1877 QQQLEERNDRLKALEENAEEKAKSglelqkllgdMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDI 1956
Cdd:PRK00409   508 KKLIGEDKEKLNELIASLEELERE----------LEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQ 577

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024469763 1957 VKKESLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVE 2017
Cdd:PRK00409   578 AIKEAKKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELK 638
DUF4175 pfam13779
Domain of unknown function (DUF4175);
691-968 9.60e-03

Domain of unknown function (DUF4175);


Pssm-ID: 463981 [Multi-domain]  Cd Length: 833  Bit Score: 41.13  E-value: 9.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  691 ELSEALKvRQDLEQELSELKSKVGEAKQEFEGKLeAERNQHKEEVEIMLKE---HEISIQDVEKVLkeelNQMkqsleek 767
Cdd:pfam13779  497 RLSEALE-RGASDEEIAKLMQELREALDDYMQAL-AEQAQQNPQDLQQPDDpnaQEMTQQDLQRML----DRI------- 563

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  768 erlleeaktreQELKESAQRSEA-ELVQVSARLME------ASLSQQNTSNEQAKQYEE--ELAKLQQKLMDlkgEKLQL 838
Cdd:pfam13779  564 -----------EELARSGRRAEAqQMLSQLQQMLEnlqagqPQQQQQQGQSEMQQAMDElgDLLREQQQLLD---ETFRQ 629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  839 SEQlVRTECQLNEVKnelelyisQVHELKQQLQEQSDENTQKAMSLTQQyESQLKDLQEEadkaKQTLTERENDI-EHVK 917
Cdd:pfam13779  630 LQQ-QGGQQQGQPGQ--------QGQQGQGQQPGQGGQQPGAQMPPQGG-AEALGDLAER----QQALRRRLEELqDELK 695

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024469763  918 KVQNEEM-EELKQKLLATEERISTL-QGDYENKLKRQENKMEKMKQKSKEMQE 968
Cdd:pfam13779  696 ELGGKEPgQALGDAGRAMRDAEEALgQGDLAGAVDAQGRALEALRKGAQQLAE 748
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 849-1086 9.66e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.07  E-value: 9.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  849 LNEVKNEL-----ELYISQVHELKQQLqeqSDENTQKAMSLTQQYE---SQLKDLQEEADKAKQTLTE-RENDIEHVKKV 919
Cdd:PRK05771    14 LKSYKDEVlealhELGVVHIEDLKEEL---SNERLRKLRSLLTKLSealDKLRSYLPKLNPLREEKKKvSVKSLEELIKD 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  920 QNEEMEELKQKLLATEERISTLQG---DYENKLKR---------------------------QENKMEKMKQKSKEMQET 969
Cdd:PRK05771    91 VEEELEKIEKEIKELEEEISELENeikELEQEIERlepwgnfdldlslllgfkyvsvfvgtvPEDKLEELKLESDVENVE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024469763  970 FKKK-----------LAEQESKLKKELenKQLEFSQKESEFNAKmlemahassagINDAVSKLESnQKEQLESLAEAHKR 1038
Cdd:PRK05771   171 YISTdkgyvyvvvvvLKELSDEVEEEL--KKLGFERLELEEEGT-----------PSELIREIKE-ELEEIEKERESLLE 236

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 2024469763 1039 ELEEISRSWEKKLNQQAEELqekhEMELQEKEQELGDLKEKLaTFSAE 1086
Cdd:PRK05771   237 ELKELAKKYLEELLALYEYL----EIELERAEALSKFLKTDK-TFAIE 279
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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