|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
10-165 |
1.47e-83 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 270.51 E-value: 1.47e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 10 LKKFTRSPLVTWVRTFGPLADENGTSLEEYMTLVDGVFLNEVMLQINPKSTNRNVNKRVNNDESLRIQNLCILVKKIKYF 89
Cdd:cd22229 1 LEQFMSSPLVTWVKTFGPLATGNGTPLDEYVALVDGVFLNEVMLQINPKSSNQRVNKKVNNDASLRIQNLSILVKQIKLY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 90 YQECLQQLIVMALPNVLIIGRNPLSEPGTNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEVTQ 165
Cdd:cd22229 81 YQETLQQLIMMSLPNVLVLGRNPLSEQGTEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
13-165 |
1.92e-59 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 201.28 E-value: 1.92e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 13 FTRSPLVTWVRTFGPladeNGTSLEEYMTLVDGVFLNEVMLQINPKSTNRNVNKRVNNDESLRIQNLCILVKKIKYFYQE 92
Cdd:cd22223 1 FLSSPLVTWAKTFAD----DGSAELSYTDLVDGVFLNNVMLQIDPRPFSEVSNRNVDDDVNARIQNLDLLLRNIKSFYQE 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 93 CLQQLIVMALPNVLIIGRNPLSEPGTNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEVTQ 165
Cdd:cd22223 77 VLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEVQHALVACIQEVTD 149
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
13-165 |
3.26e-57 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 195.14 E-value: 3.26e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 13 FTRSPLVTWVRTFGPLADENGTSLEEYMTLVDGVFLNEVMLQINPKSTNRNVNKRVNNDESLRIQNLCILVKKIKYFYQE 92
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLSMYMDLVDGVFLNKIMLQIDPRPTNQRVNKHVNNDVNLRIQNLTILVRHIKTYYQE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 93 CLQQLIVMALPNVLIIGRNPLSEPGTNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEVTQ 165
Cdd:cd22228 81 VLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIETQAAIVSHIQEVTH 153
|
|
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
11-165 |
2.61e-40 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 147.28 E-value: 2.61e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 11 KKFTRSPLVTWVRTF------------GPLADENGTSL---EEYMTLVDGVFLNEVMLQINPKSTNRNVNKRVNNDESLR 75
Cdd:cd22230 1 EEFMSGALVTWALGFeglvgeeedslgFPEEEEEEGTLdaeKRFLRLSNGDLLNRVMGIIDPSPRGGPRMRGDDGPAAHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 76 IQNLCILVKKIKYFYQECLQQLIVMALPNVLIIGRNPLSEPGTNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAA 155
Cdd:cd22230 81 VQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDLDVQAE 160
|
170
....*....|
gi 2024492573 156 VAAHIQEVTQ 165
Cdd:cd22230 161 LAEAIQEVTQ 170
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
535-1302 |
1.51e-28 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 125.55 E-value: 1.51e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 535 KEQLEKKFETLRENLER----------QIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKenkiLHESIKETSSKLN 604
Cdd:TIGR02168 174 RKETERKLERTRENLDRledilnelerQLKSLERQAEKAERYKELKAELRELELALLVLRLEE----LREELEELQEELK 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 605 KLEFEIKQVRKEMehyKEKAERAEELENELHHLEKENELLQKKIANLSItceKIEALEKEnsdldienrklkktldsLKN 684
Cdd:TIGR02168 250 EAEEELEELTAEL---QELEEKLEELRLEVSELEEEIEELQKELYALAN---EISRLEQQ-----------------KQI 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 685 LSFQLESLEKENSQLDEENLELRRRIEsskctsikmaQLQLENKELESEKEQLKKSLELMKASFKKSER----LEVSYQG 760
Cdd:TIGR02168 307 LRERLANLERQLEELEAQLEELESKLD----------ELAEELAELEEKLEELKEELESLEAELEELEAeleeLESRLEE 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 761 LDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELV--ISSKRLEQLEKENKLLEQETSQLEKDKKQLEKEN 838
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQqeIEELLKKLEEAELKELQAELEELEEELEELQEEL 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 839 KRLRQQAEIKDSTLEENNVKINHLEKEnkslFKQIAVYKESCVRLKELEMENKELVKrASIDKKTLVTLREDLVNEKLKT 918
Cdd:TIGR02168 457 ERLEEALEELREELEEAEQALDAAERE----LAQLQARLDSLERLQENLEGFSEGVK-ALLKNQSGLSGILGVLSELISV 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 919 QqmnndlEKLSHELEK-IGLNKERLLCDeqSSDDRYKLLESKLESTLKKSL-----EIKEEKIAALEARLEESTNLNQQL 992
Cdd:TIGR02168 532 D------EGYEAAIEAaLGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTflpldSIKGTEIQGNDREILKNIEGFLGV 603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 993 RQELKTVKKNYE------------------ALKQRQEEERMVQNPPP------RKGEENQSVNKWEKENQETTRELLKVK 1048
Cdd:TIGR02168 604 AKDLVKFDPKLRkalsyllggvlvvddldnALELAKKLRPGYRIVTLdgdlvrPGGVITGGSAKTNSSILERRREIEELE 683
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1049 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1128
Cdd:TIGR02168 684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1129 AQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQL 1208
Cdd:TIGR02168 764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1209 LKQKVQLEELEKVLKTEQEKMLQQNEKHE-----------TVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTL 1277
Cdd:TIGR02168 844 EEQIEELSEDIESLAAEIEELEELIEELEseleallneraSLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923
|
810 820
....*....|....*....|....*....
gi 2024492573 1278 LNNSKLGQTQLEAEF----SKLREEYQLL 1302
Cdd:TIGR02168 924 LAQLELRLEGLEVRIdnlqERLSEEYSLT 952
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
596-1394 |
5.80e-28 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 123.63 E-value: 5.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 596 IKETSSKLNKLEFEIKQVRKEMEHYKEKAERAE---ELENELHHLEKENELLQKKianlsitcEKIEALEKENSDLDIEN 672
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLKSLERQAEKAErykELKAELRELELALLVLRLE--------ELREELEELQEELKEAE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 673 RKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKCT-SIKMAQLQLENKELESEKEQLKKSLELMKASFKKS 751
Cdd:TIGR02168 253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEiSRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 752 ERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELvisSKRLEQLEKENKLLEQETSQLEKDK 831
Cdd:TIGR02168 333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL---RSKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 832 KQLEKENKRLRQQAEIKDSTLEENNVKINH--LEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLRe 909
Cdd:TIGR02168 410 ERLEDRRERLQQEIEELLKKLEEAELKELQaeLEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ- 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 910 dlvNEKLKTQQMNNDLEKLSHELEKIGLNKERLlcdeqssddryklleSKLESTLKKSLEIKEEKIAALEARLEEstNLN 989
Cdd:TIGR02168 489 ---ARLDSLERLQENLEGFSEGVKALLKNQSGL---------------SGILGVLSELISVDEGYEAAIEAALGG--RLQ 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 990 QQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETtrellkVKDRLIEVERNNATLQAEKQALK 1069
Cdd:TIGR02168 549 AVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG------FLGVAKDLVKFDPKLRKALSYLL 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1070 TQLKQLETQNNNLQAQILALQRQTV-----------------SLQEQNTTLQTQN--AKLQVENSTLNSQSTSLMNQNAQ 1130
Cdd:TIGR02168 623 GGVLVVDDLDNALELAKKLRPGYRIvtldgdlvrpggvitggSAKTNSSILERRReiEELEEKIEELEEKIAELEKALAE 702
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1131 LLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLiakHGSLKSAHKNLEVEHKDLEDRYSQLLK 1210
Cdd:TIGR02168 703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL---SKELTELEAEIEELEERLEEAEEELAE 779
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1211 QKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKLGQTQLEA 1290
Cdd:TIGR02168 780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1291 EFSKLREEyqlldikCTKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHvEQRQYIDKLN--- 1367
Cdd:TIGR02168 860 EIEELEEL-------IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE-ELREKLAQLElrl 931
|
810 820 830
....*....|....*....|....*....|..
gi 2024492573 1368 -----ELRRQKEKLEEKIMDQYKFYEPSPPRR 1394
Cdd:TIGR02168 932 eglevRIDNLQERLSEEYSLTLEEAEALENKI 963
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
505-1303 |
2.34e-26 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 118.62 E-value: 2.34e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 505 KKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLR---ENLERQIKLLEQENERSNQTIASLRQRSQIsAEAQ 581
Cdd:TIGR02168 232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlevSELEEEIEELQKELYALANEISRLEQQKQI-LRER 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 582 MKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKkianlsitcEKIEAL 661
Cdd:TIGR02168 311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE---------ELEEQL 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 662 EKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKctsikMAQLQLENKELESEKEQLKKSL 741
Cdd:TIGR02168 382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-----LKELQAELEELEEELEELQEEL 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 742 ELMKasfkksERLEVSYQGLDTENQRLQKALENSNKKIQQLEGeLQDLESENQTLQKNLEELVISSKRLEQLEkeNKLLE 821
Cdd:TIGR02168 457 ERLE------EALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGIL--GVLSE 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 822 QETSQlEKDKKQLEKENKRLRQQAEIKDstLEENNVKINHLEKEN--KSLFKQIAVYKESCVRLKELEM-ENKELVKRAS 898
Cdd:TIGR02168 528 LISVD-EGYEAAIEAALGGRLQAVVVEN--LNAAKKAIAFLKQNElgRVTFLPLDSIKGTEIQGNDREIlKNIEGFLGVA 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 899 IDKKTLVTLREDLVNEKLKT-------QQMNNDLEKLSHELEKIGLNKERLLCD----EQSSDDRYKLLESKLE-STLKK 966
Cdd:TIGR02168 605 KDLVKFDPKLRKALSYLLGGvlvvddlDNALELAKKLRPGYRIVTLDGDLVRPGgvitGGSAKTNSSILERRREiEELEE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 967 SLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERM--------VQNPPPRKGEENQSVNKWEKENQ 1038
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdlarleaeVEQLEERIAQLSKELTELEAEIE 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1039 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLN 1118
Cdd:TIGR02168 765 ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE 844
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1119 SQStslmnqnAQLLIQQSALEnekegvlKELEDLKSLYDSLlkdHEKLEHLHERQASEYESLiakhGSLKSAHKNLEVEH 1198
Cdd:TIGR02168 845 EQI-------EELSEDIESLA-------AEIEELEELIEEL---ESELEALLNERASLEEAL----ALLRSELEELSEEL 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1199 KDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQ-NEKHETVAAEYkklRDENDRLAHTHDQLLKENEVLQTDHKNLKTL 1277
Cdd:TIGR02168 904 RELESKRSELRRELEELREKLAQLELRLEGLEVRiDNLQERLSEEY---SLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
810 820
....*....|....*....|....*...
gi 2024492573 1278 LNNskLGQTQLEA--EFSKLREEYQLLD 1303
Cdd:TIGR02168 981 IKE--LGPVNLAAieEYEELKERYDFLT 1006
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
194-1012 |
2.36e-26 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 118.62 E-value: 2.36e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 194 TLHLRRLVDERDEHLETIIELSEDRDSLhllpqasaaqspcgspglkhTESKQHLSVELADAKAKIRRLRQEIEEKNEQF 273
Cdd:TIGR02168 231 VLRLEELREELEELQEELKEAEEELEEL--------------------TAELQELEEKLEELRLEVSELEEEIEELQKEL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 274 LDYKQELERVETELRRLQQENKNLLSDarsarvyrdeldiLREKAIRVDKLESEVGRYKERLHDMEFYKARVEELMEDNQ 353
Cdd:TIGR02168 291 YALANEISRLEQQKQILRERLANLERQ-------------LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 354 VMLETKRmfedqvKTLQCRSDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEMAQKQSMDESLHLGWELE 433
Cdd:TIGR02168 358 AELEELE------AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 434 QINRFTDHSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIvKMEKENQRLNKKIEELEKE 513
Cdd:TIGR02168 432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL-DSLERLQENLEGFSEGVKA 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 514 IVQEKQSLQDNQNLSKDLMKEKEQLEKKFET-LRENLErqiKLLEQENERSNQTIASLRQ----RSQISAEAQMK--EIE 586
Cdd:TIGR02168 511 LLKNQSGLSGILGVLSELISVDEGYEAAIEAaLGGRLQ---AVVVENLNAAKKAIAFLKQnelgRVTFLPLDSIKgtEIQ 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 587 KENKILHESIKETSSKLNKLEFEIKQVRKEME------HYKEKAERAEELENELHHLE----KENELLQKK--------I 648
Cdd:TIGR02168 588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvLVVDDLDNALELAKKLRPGYrivtLDGDLVRPGgvitggsaK 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 649 ANLSITCEKIEalekensdLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESskcTSIKMAQLQLENK 728
Cdd:TIGR02168 668 TNSSILERRRE--------IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE---LSRQISALRKDLA 736
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 729 ELESEKEQLKKSLELMKasfKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELvisSK 808
Cdd:TIGR02168 737 RLEAEVEQLEERIAQLS---KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL---RA 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 809 RLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVykescvrLKELEM 888
Cdd:TIGR02168 811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-------LLNERA 883
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 889 ENKELVKRAsidKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDR----YKLLE---SKLE 961
Cdd:TIGR02168 884 SLEEALALL---RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlseeYSLTLeeaEALE 960
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 962 STLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEE 1012
Cdd:TIGR02168 961 NKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKED 1011
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
276-1082 |
1.34e-24 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 112.84 E-value: 1.34e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 276 YKQEleRVETElRRLQQENKNLlsdarsARVYrdelDILREKAIRVDKLESEVG---RYKE-----RLHDMEFYKARVEE 347
Cdd:TIGR02168 170 YKER--RKETE-RKLERTRENL------DRLE----DILNELERQLKSLERQAEkaeRYKElkaelRELELALLVLRLEE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 348 LMEDNQVMLETKRMFEDQVKTLQcrsDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEMaQKQSMDESL- 426
Cdd:TIGR02168 237 LREELEELQEELKEAEEELEELT---AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ-QKQILRERLa 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 427 HLGWELEQINRFTDHSEVSHKSLGLEVTELTSsRLLKLEKENQSLLKTVEELRSTMDDSvggnSSRIVKMEKENQRLNKK 506
Cdd:TIGR02168 313 NLERQLEELEAQLEELESKLDELAEELAELEE-KLEELKEELESLEAELEELEAELEEL----ESRLEELEEQLETLRSK 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 507 IEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLER-QIKLLEQENERSNQTIASLRQRsQISAEAQMKEI 585
Cdd:TIGR02168 388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEE-LERLEEALEEL 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 586 EKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIA---------------- 649
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyeaaieaalggr 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 650 -------NLSITCEKIEALEKENS--------DLDIENRKLKKTLDSLKNLSFQLESLekenSQLDEENLELRRRIES-- 712
Cdd:TIGR02168 547 lqavvveNLNAAKKAIAFLKQNELgrvtflplDSIKGTEIQGNDREILKNIEGFLGVA----KDLVKFDPKLRKALSYll 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 713 ---SKCTSIKMAQLQLenKELESEKEQLKKSLELMKASF---KKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGEL 786
Cdd:TIGR02168 623 ggvLVVDDLDNALELA--KKLRPGYRIVTLDGDLVRPGGvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKAL 700
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 787 QDLESENQTLQKNLEELVI----SSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHL 862
Cdd:TIGR02168 701 AELRKELEELEEELEQLRKeleeLSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 863 EKENKSLFKQIAVYKESCV----RLKELEMENKELVKRASidkkTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLN 938
Cdd:TIGR02168 781 EAEIEELEAQIEQLKEELKalreALDELRAELTLLNEEAA----NLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 939 KERLLCDEQSSddrykllESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEeermvqn 1018
Cdd:TIGR02168 857 LAAEIEELEEL-------IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE------- 922
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1019 ppprkgEENQSVNKWEK------ENQETTREllKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL 1082
Cdd:TIGR02168 923 ------KLAQLELRLEGlevridNLQERLSE--EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
16-165 |
1.69e-24 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 101.20 E-value: 1.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 16 SPLVTWVRTFGPLadengTSLEEYMTLVDGVFLNEVMLQINPKSTNRNVNKRVNNDES--LRIQNLCILVKKIKYFYQEC 93
Cdd:cd22211 2 AALLAWINTFPLS-----SPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSSDNwvLKLNNLKKLYRSLSKYYREV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 94 LQQLIV-MALPNVLIIGRNPlsepGTNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEVTQ 165
Cdd:cd22211 77 LGQQLSdLPLPDLSAIARDG----DEEEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
460-1273 |
1.63e-23 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 109.39 E-value: 1.63e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 460 RLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLE 539
Cdd:TIGR02169 199 QLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELN 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 540 KKFETLRENLERQIK--LLEQENERSNQtiaslrQRSQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKE- 616
Cdd:TIGR02169 279 KKIKDLGEEEQLRVKekIGELEAEIASL------ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRr 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 617 ---MEHYKEKAERAEELENELHHLEKENELLQKKIANLSitcEKIEALEKENSDLDIENRKLKKTLDSLK----NLSFQL 689
Cdd:TIGR02169 353 dklTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR---EKLEKLKREINELKRELDRLQEELQRLSeelaDLNAAI 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 690 ESLEKENSQLDEENLELRRRIESS--KCTSIKmAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQR 767
Cdd:TIGR02169 430 AGIEAKINELEEEKEDKALEIKKQewKLEQLA-ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRG 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 768 LQKALENSNKKIQQLEGELQDLESENQTLQKNLEelVISSKRLEQLEKENKLLEQETSQLEKDKK-------QLEKENKR 840
Cdd:TIGR02169 509 GRAVEEVLKASIQGVHGTVAQLGSVGERYATAIE--VAAGNRLNNVVVEDDAVAKEAIELLKRRKagratflPLNKMRDE 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 841 LRQQAEIKDSTLEENNVKINHLEKENKSLFKQiaVYKESCVrlkeleMENKELVKRAsIDKKTLVTLREDLVN------- 913
Cdd:TIGR02169 587 RRDLSILSEDGVIGFAVDLVEFDPKYEPAFKY--VFGDTLV------VEDIEAARRL-MGKYRMVTLEGELFEksgamtg 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 914 --------------EKLKTQQMNNDLEKLSHELEKIGLNKERLlcdEQSSDDRYKLLE--SKLESTLKKSLEIKEEKIAA 977
Cdd:TIGR02169 658 gsraprggilfsrsEPAELQRLRERLEGLKRELSSLQSELRRI---ENRLDELSQELSdaSRKIGEIEKEIEQLEQEEEK 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 978 LEARLEESTNLNQQLRQEL---KTVKKNYEALKQRQEEE----RMVQNPPPRKgEENQSVNKWEKENQETTRELLKVKDR 1050
Cdd:TIGR02169 735 LKERLEELEEDLSSLEQEIenvKSELKELEARIEELEEDlhklEEALNDLEAR-LSHSRIPEIQAELSKLEEEVSRIEAR 813
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1051 LIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ 1130
Cdd:TIGR02169 814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1131 LLIQQSALENEKEGVLKELEDLKSLyDSLLKdhEKLEHLHErQASEYESLIAKHGSLKSahknlevEHKDLEDRYSQLLK 1210
Cdd:TIGR02169 894 LEAQLRELERKIEELEAQIEKKRKR-LSELK--AKLEALEE-ELSEIEDPKGEDEEIPE-------EELSLEDVQAELQR 962
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024492573 1211 QKVQLEELEKV-LKTEQEkmlqqnekHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKN 1273
Cdd:TIGR02169 963 VEEEIRALEPVnMLAIQE--------YEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
596-1378 |
3.97e-23 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 107.85 E-value: 3.97e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 596 IKETSSKLNKLEFEIKQVRKEMEHY----KEKAERAEELENELHHLEKENELLQKKI-ANLSITCEKIEALEKENSDLDI 670
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLdliiDEKRQQLERLRREREKAERYQALLKEKReYEGYELLKEKEALERQKEAIER 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 671 ENRKLKKTLDSLKnlsFQLESLEKENSQLDEENLELRRRIEssKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKK 750
Cdd:TIGR02169 245 QLASLEEELEKLT---EEISELEKRLEEIEQLLEELNKKIK--DLGEEEQLRVKEKIGELEAEIASLERSIAEKERELED 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 751 SERLEvsyQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVissKRLEQLEKENKLLEQETSQLEKD 830
Cdd:TIGR02169 320 AEERL---AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR---AELEEVDKEFAETRDELKDYREK 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 831 KKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKEscvRLKELEMENKELVKRASIDKKTLVTLRED 910
Cdd:TIGR02169 394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE---EKEDKALEIKKQEWKLEQLAADLSKYEQE 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 911 LVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLES---TLKKSLEIKEEKIAALEARLeeSTN 987
Cdd:TIGR02169 471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgTVAQLGSVGERYATAIEVAA--GNR 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 988 LNQQLRQELKTVKKNYEALKQRQ------------EEERMVQNPPPRKGEENQSVN------KWEK------------EN 1037
Cdd:TIGR02169 549 LNNVVVEDDAVAKEAIELLKRRKagratflplnkmRDERRDLSILSEDGVIGFAVDlvefdpKYEPafkyvfgdtlvvED 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1038 QETTR-----------------------------------------ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1076
Cdd:TIGR02169 629 IEAARrlmgkyrmvtlegelfeksgamtggsraprggilfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELS 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1077 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLK--- 1153
Cdd:TIGR02169 709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEarl 788
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1154 --SLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQ 1231
Cdd:TIGR02169 789 shSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE 868
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1232 QNEKHEtvaaeyKKLRDENDRLAHthdqllkenevLQTDHKNLKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKCTKISN 1311
Cdd:TIGR02169 869 ELEELE------AALRDLESRLGD-----------LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE 931
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 1312 QCELLSQLKGNMEEENRHLLD------QIQTLMLQNRTLLEQNMESKDLFHVEQRQYidklNELRRQKEKLEE 1378
Cdd:TIGR02169 932 ELSEIEDPKGEDEEIPEEELSledvqaELQRVEEEIRALEPVNMLAIQEYEEVLKRL----DELKEKRAKLEE 1000
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1227 |
7.86e-23 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 106.69 E-value: 7.86e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 610 IKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSitcEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQL 689
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEIS---SELPELREELEKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 690 ESLEKENSQLDEENLELRRRIESSKctsikmaqlqlenKELESEKEQLKKSLELmkasfkkserlevsyQGLDTENQRLQ 769
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELK-------------KEIEELEEKVKELKEL---------------KEKAEEYIKLS 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 770 KALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLE----KENKRLRQQA 845
Cdd:PRK03918 300 EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEeakaKKEELERLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 846 EIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKtqqmnNDL 925
Cdd:PRK03918 380 RLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRK-----ELL 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 926 EKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLEstlkksleiKEEKIAALEARLEESTNLnqqlrqELKTVKKNYEA 1005
Cdd:PRK03918 455 EEYTAELKRIEKELKEIEEKERKLRKELRELEKVLK---------KESELIKLKELAEQLKEL------EEKLKKYNLEE 519
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1006 LKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLqaEKQALKTQLKQLETQNNNLQaQ 1085
Cdd:PRK03918 520 LEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL--LKELEELGFESVEELEERLK-E 596
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1086 ILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaqlliqqSALENEKEGVLKELEDLKSLYDSllKDHEK 1165
Cdd:PRK03918 597 LEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL-----------AETEKRLEELRKELEELEKKYSE--EEYEE 663
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 1166 LEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQE 1227
Cdd:PRK03918 664 LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
493-1203 |
1.50e-22 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 105.49 E-value: 1.50e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 493 IVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQ 572
Cdd:TIGR04523 28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 573 -RSQI-SAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEH----YKEKAERAEELENELHHLEKENELLQK 646
Cdd:TIGR04523 108 iNSEIkNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKlnnkYNDLKKQKEELENELNLLEKEKLNIQK 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 647 KIAN-----------LSITCEKIE---ALEKENSDLDIENRKLKKTLDSLKN--------LSFQLESLEKENSQLDEENL 704
Cdd:TIGR04523 188 NIDKiknkllklellLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQeinektteISNTQTQLNQLKDEQNKIKK 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 705 ELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQ--RLQKALENSNKKIQQL 782
Cdd:TIGR04523 268 QLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQisQNNKIISQLNEQISQL 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 783 EGELQDLESENQTLQKNLEElviSSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHL 862
Cdd:TIGR04523 348 KKELTNSESENSEKQRELEE---KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 863 EKENKSLFKQIAVYKESCVRLKELEMENKELVKrasidkktlvtlredlvNEKLKTQQMNNDLEKLSHELEKIglnkerl 942
Cdd:TIGR04523 425 EKEIERLKETIIKNNSEIKDLTNQDSVKELIIK-----------------NLDNTRESLETQLKVLSRSINKI------- 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 943 lcdeqssddrykllesklestlKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEE---ERMVQNP 1019
Cdd:TIGR04523 481 ----------------------KQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKlesEKKEKES 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1020 PPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQ 1099
Cdd:TIGR04523 539 KISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1100 NTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDS---LLKDHEKLEHLHERQASE 1176
Cdd:TIGR04523 619 LEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDiieLMKDWLKELSLHYKKYIT 698
|
730 740
....*....|....*....|....*..
gi 2024492573 1177 YESLIAKHGSLKSAHKNLEVEHKDLED 1203
Cdd:TIGR04523 699 RMIRIKDLPKLEEKYKEIEKELKKLDE 725
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
502-1298 |
1.72e-22 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 105.82 E-value: 1.72e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 502 RLNKKIEELEKEIVQEKQSLQDNQN----LSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQIS 577
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIIdleeLKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 578 AEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSITCEK 657
Cdd:pfam02463 246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 658 IEALEKENSDLDIENRKLKKTLDSLKNlsfQLESLEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKE-- 735
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELKELEIKRE---AEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKse 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 736 ---------QLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTlqKNLEELVIS 806
Cdd:pfam02463 403 eekeaqlllELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE--DLLKETQLV 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 807 SKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKES--CVRLK 884
Cdd:pfam02463 481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsaTADEV 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 885 ELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTL 964
Cdd:pfam02463 561 EERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKES 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 965 KKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNyEALKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETTREL 1044
Cdd:pfam02463 641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEI-QELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEA 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1045 LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1124
Cdd:pfam02463 720 EELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQ 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1125 MNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEhlHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDR 1204
Cdd:pfam02463 800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL--KEEQKLEKLAEEELERLEEEITKEELLQELLLKEE 877
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1205 YSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKLG 1284
Cdd:pfam02463 878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEE 957
|
810
....*....|....
gi 2024492573 1285 QTQLEAEFSKLREE 1298
Cdd:pfam02463 958 EEERNKRLLLAKEE 971
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
628-1354 |
8.45e-21 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 99.71 E-value: 8.45e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 628 EELENELHHLEKENELLQKKIANLSITCEKIEAlEKENSDLDIENrkLKKTLDSLKNlsfqleSLEKENSQLDEENLELR 707
Cdd:TIGR04523 36 KQLEKKLKTIKNELKNKEKELKNLDKNLNKDEE-KINNSNNKIKI--LEQQIKDLND------KLKKNKDKINKLNSDLS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 708 RRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSyqgLDTENQRLQKALENSNKKIQQLEGELQ 787
Cdd:TIGR04523 107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEK---LNNKYNDLKKQKEELENELNLLEKEKL 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 788 DLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKenkrlrqqaeikdsTLEENNVKINHLEKENK 867
Cdd:TIGR04523 184 NIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKD--------------NIEKKQQEINEKTTEIS 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 868 SLFKQIAVYKESCVRLKElEMENKELvkrasidkktlvtlreDLVNEKLKTQQMNNDLEKLSHELEKigLNKERllcdeq 947
Cdd:TIGR04523 250 NTQTQLNQLKDEQNKIKK-QLSEKQK----------------ELEQNNKKIKELEKQLNQLKSEISD--LNNQK------ 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 948 ssddrykllESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKnyealkqrqeeermvqnppprkgeen 1027
Cdd:TIGR04523 305 ---------EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK-------------------------- 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1028 qSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1107
Cdd:TIGR04523 350 -ELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1108 AKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSL 1187
Cdd:TIGR04523 429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKEL 508
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1188 KSAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQEKMlQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVL 1267
Cdd:TIGR04523 509 EEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD-DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEK 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1268 QTDHKNLKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNRTLLEQ 1347
Cdd:TIGR04523 588 QELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKK 667
|
....*..
gi 2024492573 1348 NMESKDL 1354
Cdd:TIGR04523 668 IKESKTK 674
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
596-1217 |
2.08e-20 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 98.86 E-value: 2.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 596 IKETSSKLNKLEFEIKQVRKEMEHYK---EKAERAEELENELHhlEKENELLQKKIANLSitcEKIEALEKENSDLDIEN 672
Cdd:COG1196 181 LEATEENLERLEDILGELERQLEPLErqaEKAERYRELKEELK--ELEAELLLLKLRELE---AELEELEAELEELEAEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 673 RKLKKtldslknlsfQLESLEKENSQLDEENLELRRRIEsskctsikmaQLQLENKELESEKEQLKKSLELMKasfKKSE 752
Cdd:COG1196 256 EELEA----------ELAELEAELEELRLELEELELELE----------EAQAEEYELLAELARLEQDIARLE---ERRR 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELvisSKRLEQLEKENKLLEQETSQLEKDKK 832
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA---EEALLEAEAELAEAEEELEELAEELL 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 833 QLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLV 912
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 913 NEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTL---KKSLEIKEEKIAALEARLEESTNLN 989
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagAVAVLIGVEAAYEAALEAALAAALQ 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 990 QQLRQELKTVKKNYEALKQR-----------QEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNN 1058
Cdd:COG1196 550 NIVVEDDEVAAAAIEYLKAAkagratflpldKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1059 ATLQAEKQALKTQ-------LKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQL 1131
Cdd:COG1196 630 ARLEAALRRAVTLagrlrevTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1132 LIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLE--------------VE 1197
Cdd:COG1196 710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEreiealgpvnllaiEE 789
|
650 660
....*....|....*....|
gi 2024492573 1198 HKDLEDRYSQLLKQKVQLEE 1217
Cdd:COG1196 790 YEELEERYDFLSEQREDLEE 809
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
308-1212 |
1.42e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 96.29 E-value: 1.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 308 RDELDILREKAIRVDKLESEVGRYKERLH----DMEFYKARVEELMEDNQ-VMLETKRMFEDQVKTLQCRSDKLhvvEKE 382
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRrereKAERYQALLKEKREYEGyELLKEKEALERQKEAIERQLASL---EEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 383 NLQLKAKLHEMEMERDMDRKKIEELMEENMAL---EMAQKQSMDESLHLgwELEQINRFTDHSEVSHKSLglevteltSS 459
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeEQLRVKEKIGELEA--EIASLERSIAEKERELEDA--------EE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 460 RLLKLEKENQSLLKTVEELrstmDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLE 539
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEEL----EREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 540 KKFETLRENLERQIKLLEQENERSNQtiaslrqrsqisAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEH 619
Cdd:TIGR02169 399 REINELKRELDRLQEELQRLSEELAD------------LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 620 YKEKAERaeeLENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIEnrkLKKTLDSLKNLSFQLESLEK----- 694
Cdd:TIGR02169 467 YEQELYD---LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEV---LKASIQGVHGTVAQLGSVGEryata 540
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 695 --------------ENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQG 760
Cdd:TIGR02169 541 ievaagnrlnnvvvEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVF 620
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 761 LDT---ENQRLQKALENSNKKIqQLEGELqdLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSqLEKDKKQLEKE 837
Cdd:TIGR02169 621 GDTlvvEDIEAARRLMGKYRMV-TLEGEL--FEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEG-LKRELSSLQSE 696
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 838 NKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKEscvRLKELEMENKELVKRASIDKKTLVTLREDLvneklk 917
Cdd:TIGR02169 697 LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE---RLEELEEDLSSLEQEIENVKSELKELEARI------ 767
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 918 tQQMNNDLEKLSHELEKIglnkERLLcdeqsSDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEESTNLNQQLRQELK 997
Cdd:TIGR02169 768 -EELEEDLHKLEEALNDL----EARL-----SHSRIPEIQAELSK-LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ 836
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 998 TVKKNYEALKQRQEEERmvqnppprkgeenqsvnkwekenqettRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLET 1077
Cdd:TIGR02169 837 ELQEQRIDLKEQIKSIE---------------------------KEIENLNGKKEELEEELEELEAALRDLESRLGDLKK 889
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1078 QNNNLQAQILALQRQtvsLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLkELEDLKSLYD 1157
Cdd:TIGR02169 890 ERDELEAQLRELERK---IEELEAQIEKKRKRL----SELKAKLEALEEELSEIEDPKGEDEEIPEEEL-SLEDVQAELQ 961
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 1158 SLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQK 1212
Cdd:TIGR02169 962 RVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
490-935 |
1.57e-19 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 95.47 E-value: 1.57e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 490 SSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQ----NLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQ 565
Cdd:TIGR04523 217 ESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQtqlnQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 566 TIASLRQRSQI---SAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHY----KEKAERAEELENELHHLE 638
Cdd:TIGR04523 297 ISDLNNQKEQDwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSesenSEKQRELEEKQNEIEKLK 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 639 KENEllQKKianlsitcEKIEALEKENSDLdieNRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKCT-- 716
Cdd:TIGR04523 377 KENQ--SYK--------QEIKNLESQINDL---ESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEik 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 717 --SIKMAQLQLENKELESEKEQLKKSLELMKASFKKserlevsyqgLDTENQRLQKALENSNKKIQQLEGELQDLESENQ 794
Cdd:TIGR04523 444 dlTNQDSVKELIIKNLDNTRESLETQLKVLSRSINK----------IKQNLEQKQKELKSKEKELKKLNEEKKELEEKVK 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 795 TLQKNLEELVissKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIkdstlEENNVKINHLEKENKSLFKQia 874
Cdd:TIGR04523 514 DLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEI-----DEKNKEIEELKQTQKSLKKK-- 583
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 875 vYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLV-----NEKLKTQQMN--NDLEKLSHELEKI 935
Cdd:TIGR04523 584 -QEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEkakkeNEKLSSIIKNikSKKNKLKQEVKQI 650
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
253-1078 |
2.01e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 95.91 E-value: 2.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 253 ADAKAKIRRLRQEIEEKNEQfldykqeLERVETELRRLQQENKNLLSDARSARVYRDELDILRE-----KAIRVDKLESE 327
Cdd:TIGR02169 166 AEFDRKKEKALEELEEVEEN-------IERLDLIIDEKRQQLERLRREREKAERYQALLKEKREyegyeLLKEKEALERQ 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 328 VGRYKERLHDMEFYKARVEELMEDNQVMLETKrmfEDQVKTLQCRSDKLHvvEKENLQLKAKLHEMEMERDMDRKKIEEL 407
Cdd:TIGR02169 239 KEAIERQLASLEEELEKLTEEISELEKRLEEI---EQLLEELNKKIKDLG--EEEQLRVKEKIGELEAEIASLERSIAEK 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 408 MEENMALEMAQKQSMDESLHLGWELEQINRFTDHSEVSHKSLGLEVTELTS------SRLLKLEKENQ-------SLLKT 474
Cdd:TIGR02169 314 ERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEeledlrAELEEVDKEFAetrdelkDYREK 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 475 VEELRSTMDDSVGGNS---SRIVKMEKENQRLNKKIEELEKEIVQ---EKQSLQDN--------QNLSKDLMKEKEQLEK 540
Cdd:TIGR02169 394 LEKLKREINELKRELDrlqEELQRLSEELADLNAAIAGIEAKINEleeEKEDKALEikkqewklEQLAADLSKYEQELYD 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 541 KFETLREnLERQIKLLEQENERSNQTIASLRQRsQISAEAQMKEIEKENKILHESIKE---------------TSSKLNK 605
Cdd:TIGR02169 474 LKEEYDR-VEKELSKLQRELAEAEAQARASEER-VRGGRAVEEVLKASIQGVHGTVAQlgsvgeryataievaAGNRLNN 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 606 LEFEIKQVRKEMEHY--KEKAERAEELE-NELHHLEKENELLQKK----IANLSITCE-KIEALEKEN-------SDLDI 670
Cdd:TIGR02169 552 VVVEDDAVAKEAIELlkRRKAGRATFLPlNKMRDERRDLSILSEDgvigFAVDLVEFDpKYEPAFKYVfgdtlvvEDIEA 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 671 ENRKLKK----TLD--------SLKNLSFQLESLEKENSQLDEENLELRRRIESSKctsIKMAQLQLENKELESEKEQLK 738
Cdd:TIGR02169 632 ARRLMGKyrmvTLEgelfeksgAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLK---RELSSLQSELRRIENRLDELS 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 739 KSlelMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLE--ELVISSKRLEQLEKE 816
Cdd:TIGR02169 709 QE---LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEelEEDLHKLEEALNDLE 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 817 NKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKEscvRLKELEMENKELVKR 896
Cdd:TIGR02169 786 ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE---QIKSIEKEIENLNGK 862
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 897 asidkktlvtlREDLVNEKLKTQQMNNDLEKlshelEKIGLNKERLLCDEQssddrYKLLESKLEsTLKKSLEIKEEKIA 976
Cdd:TIGR02169 863 -----------KEELEEELEELEAALRDLES-----RLGDLKKERDELEAQ-----LRELERKIE-ELEAQIEKKRKRLS 920
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 977 ALEARLEEstnlnqqLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVER 1056
Cdd:TIGR02169 921 ELKAKLEA-------LEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKE 993
|
890 900
....*....|....*....|..
gi 2024492573 1057 NNATLQAEKQALKTQLKQLETQ 1078
Cdd:TIGR02169 994 KRAKLEEERKAILERIEEYEKK 1015
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
251-814 |
3.43e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 94.75 E-value: 3.43e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 251 ELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDELDILREkaiRVDKLESEVGR 330
Cdd:PRK03918 201 ELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEE---RIEELKKEIEE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 331 YKERLHDMEFYKARVEELMEDNQVMLETKRMFEDQVKTLQCRSDKLHVVE---KENLQLKAKLHEMEMERDMDRKKIEEL 407
Cdd:PRK03918 278 LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEeriKELEEKEERLEELKKKLKELEKRLEEL 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 408 MEENMALEMAqKQSMDESLHL-----GWELEQINRFTDHSEVSHKSLGLEVTELTsSRLLKLEKENQSLLKTVEELRstm 482
Cdd:PRK03918 358 EERHELYEEA-KAKKEELERLkkrltGLTPEKLEKELEELEKAKEEIEEEISKIT-ARIGELKKEIKELKKAIEELK--- 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 483 ddsvggnssrivKMEKENQRLNKKIEELEKEIVQEKQSLQdnqnlSKDLMKEKEQLEKKFETLRENLERQIKLLEQENE- 561
Cdd:PRK03918 433 ------------KAKGKCPVCGRELTEEHRKELLEEYTAE-----LKRIEKELKEIEEKERKLRKELRELEKVLKKESEl 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 562 -RSNQTIASLRQRSQISAEAQMKEIEKENkilhESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKE 640
Cdd:PRK03918 496 iKLKELAEQLKELEEKLKKYNLEELEKKA----EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEE 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 641 NELLQKKIANLSITCekIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEenlelrrriesskctsiKM 720
Cdd:PRK03918 572 LAELLKELEELGFES--VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDK-----------------AF 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 721 AQLQLENKELESEKEQLKKSLElmKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNL 800
Cdd:PRK03918 633 EELAETEKRLEELRKELEELEK--KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAK 710
|
570
....*....|....
gi 2024492573 801 EELVISSKRLEQLE 814
Cdd:PRK03918 711 KELEKLEKALERVE 724
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
362-1154 |
5.61e-19 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 94.41 E-value: 5.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 362 FEDQVKTLQCR---SDKLHVVEKENLQ-----LKAKLHEMEMERD--MDRKKIEELMEENMalemaqKQSMDESLHlgwE 431
Cdd:pfam15921 83 YSHQVKDLQRRlneSNELHEKQKFYLRqsvidLQTKLQEMQMERDamADIRRRESQSQEDL------RNQLQNTVH---E 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 432 LEqinrftdhsevSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKEN----QRLNKKI 507
Cdd:pfam15921 154 LE-----------AAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMStmhfRSLGSAI 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 508 EELEKEIVQEKQSLQDNQNLSKDLMKE-KEQLEKKFETLRENLERQIKLLEQENERSnqtIASLRQRSQiSAEAQMKEIE 586
Cdd:pfam15921 223 SKILRELDTEISYLKGRIFPVEDQLEAlKSESQNKIELLLQQHQDRIEQLISEHEVE---ITGLTEKAS-SARSQANSIQ 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 587 KENKILHESIKETSS----KLNKLEFEIKQVRKEMEHYKEKAE-RAEELENELhhlekenellqkKIANLSITCEKIE-- 659
Cdd:pfam15921 299 SQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEdKIEELEKQL------------VLANSELTEARTErd 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 660 ALEKENSDLDienrklkktlDSLKNLSFQLESLEKENSQLDEENlelRRRIESSKCTSIKMAQLQLENKELESEKEQLKK 739
Cdd:pfam15921 367 QFSQESGNLD----------DQLQKLLADLHKREKELSLEKEQN---KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEA 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 740 SLELMKASFkkserlevsyQGldtENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELviSSKRLeQLEKENKL 819
Cdd:pfam15921 434 LLKAMKSEC----------QG---QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEEL--TAKKM-TLESSERT 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 820 LEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEEnnvkINHLEKENKSLFKqiavYKESCVRLKeLEMENKElvkrasi 899
Cdd:pfam15921 498 VSDLTASLQEKERAIEATNAEITKLRSRVDLKLQE----LQHLKNEGDHLRN----VQTECEALK-LQMAEKD------- 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 900 dkKTLVTLREDLVNEKLKTQQMNNDLEKLshELEKIGLNKErlLCDEQSSDDRYKLLESKLESTLKK------SLEIKEE 973
Cdd:pfam15921 562 --KVIEILRQQIENMTQLVGQHGRTAGAM--QVEKAQLEKE--INDRRLELQEFKILKDKKDAKIRElearvsDLELEKV 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 974 KIA-ALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEEnqsvnkwekenQETTRELLKVKDRli 1052
Cdd:pfam15921 636 KLVnAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEE-----------METTTNKLKMQLK-- 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1053 evernnaTLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLL 1132
Cdd:pfam15921 703 -------SAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLS 775
|
810 820
....*....|....*....|..
gi 2024492573 1133 IQQSALENEKEGVLKELEDLKS 1154
Cdd:pfam15921 776 QELSTVATEKNKMAGELEVLRS 797
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
136-878 |
1.43e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 93.21 E-value: 1.43e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 136 QKKEEFIERIQHLDFDTRAAVAAHIQEVTQNQENVFDlqwmdvivfTQDSVEPLLKNMTLHLRRLVDERDEHLETIIELS 215
Cdd:TIGR02169 272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER---------SIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 216 EDRDSLHLLpqasaaqspcgspglkhtesKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENK 295
Cdd:TIGR02169 343 REIEEERKR--------------------RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 296 NLlsdarsarvyRDELDILREKAIRvdkLESEVGRYKERLHDMEFYKARVEELMEDNQVMLETKrmfEDQVKTLQcrsDK 375
Cdd:TIGR02169 403 EL----------KRELDRLQEELQR---LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ---EWKLEQLA---AD 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 376 LHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEMAQKQSMDESLHLGWELEQI-NRFTDHSEVSHK-SLGLEV 453
Cdd:TIGR02169 464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhGTVAQLGSVGERyATAIEV 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 454 ------------TELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSR----------------------------- 492
Cdd:TIGR02169 544 aagnrlnnvvveDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSedgvigfavdlvefdpkyepafkyvfgdt 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 493 -IVKMEKENQRLNKKIE--ELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLR---ENLERQIKLLEQENERSNQT 566
Cdd:TIGR02169 624 lVVEDIEAARRLMGKYRmvTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRerlEGLKRELSSLQSELRRIENR 703
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 567 IASLRQRSQiSAEAQMKEIEKENKIL-------HESIKETSSKLNKLEFEIKQVRKEMEHYkekAERAEELENELHHLEK 639
Cdd:TIGR02169 704 LDELSQELS-DASRKIGEIEKEIEQLeqeeeklKERLEELEEDLSSLEQEIENVKSELKEL---EARIEELEEDLHKLEE 779
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 640 ENELLQKKIANlsitcEKIEALEKENSDLDIENRKLKKTLDS----LKNLSFQLESLEKENSQLDEENLELRRRIESSKC 715
Cdd:TIGR02169 780 ALNDLEARLSH-----SRIPEIQAELSKLEEEVSRIEARLREieqkLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 716 T----SIKMAQLQLENKELESEKEQLKKSLELMKasfKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLES 791
Cdd:TIGR02169 855 EienlNGKKEELEEELEELEAALRDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE 931
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 792 ENQTLQKNLEELVISSKRLEQLEKenklLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFK 871
Cdd:TIGR02169 932 ELSEIEDPKGEDEEIPEEELSLED----VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
|
....*..
gi 2024492573 872 QIAVYKE 878
Cdd:TIGR02169 1008 RIEEYEK 1014
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
243-873 |
1.86e-18 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 92.01 E-value: 1.86e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 243 ESKQHLSVELADAKakirrlrQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDEL-DILREKAIRV 321
Cdd:TIGR04523 117 EQKNKLEVELNKLE-------KQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLeKEKLNIQKNI 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 322 DKLESEVGRYKERLHDMEFYKARVEELMEDNQVMLETKRMFEDQVKTLQcrsdklhvveKENLQLKAKLHEMEmerdmdr 401
Cdd:TIGR04523 190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQ----------QEINEKTTEISNTQ------- 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 402 KKIEELMEENmalEMAQKQSMDESLhlgwELEQINRFTDHSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRST 481
Cdd:TIGR04523 253 TQLNQLKDEQ---NKIKKQLSEKQK----ELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEE 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 482 MDdsvggnsSRIVKMEKENQRLNKKIEELEKEIvqekqslqdnQNLSKDLMKEKEQLEKKfetlrenlERQIKLLEQENE 561
Cdd:TIGR04523 326 IQ-------NQISQNNKIISQLNEQISQLKKEL----------TNSESENSEKQRELEEK--------QNEIEKLKKENQ 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 562 RSNQTIASLRQRSQiSAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMehykekaeraEELENELHHLEKEN 641
Cdd:TIGR04523 381 SYKQEIKNLESQIN-DLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETI----------IKNNSEIKDLTNQD 449
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 642 ELLQKKIANLSITcekIEALEKENSDLDIENRKLKKTLD----SLKNLSFQLESLEKENSQLDEENLELRRRIESSKcts 717
Cdd:TIGR04523 450 SVKELIIKNLDNT---RESLETQLKVLSRSINKIKQNLEqkqkELKSKEKELKKLNEEKKELEEKVKDLTKKISSLK--- 523
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 718 IKMAQLQLENKELESEKEQLKKSLELMKASFKKSErLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQ 797
Cdd:TIGR04523 524 EKIEKLESEKKEKESKISDLEDELNKDDFELKKEN-LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI 602
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 798 KNLEELVISskrLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQI 873
Cdd:TIGR04523 603 KEIEEKEKK---ISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKI 675
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
497-1076 |
3.06e-18 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 91.92 E-value: 3.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 497 EKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQ--RS 574
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 575 QISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEhykEKAERAEELENELHHLEKENELLQKKIAnlsit 654
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE---EAEEELEEAEAELAEAEEALLEAEAELA----- 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 655 cEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKctsikmAQLQLENKELESEK 734
Cdd:COG1196 376 -EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE------EEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 735 EQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQT--LQKNLEELVISSKRLEQ 812
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkAALLLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 813 LEKENKLLEQ---------------ETSQLEKDKKQLEKENKRLR----QQAEIKDSTLEENNVKINHLEKENKSLFKQI 873
Cdd:COG1196 529 LIGVEAAYEAaleaalaaalqnivvEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDL 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 874 AVYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLlcdEQSSDDRY 953
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA---EAELEELA 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 954 KLLESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSVNKW 1033
Cdd:COG1196 686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1034 EKENQETTRELlkvkDRLIEVernN-------ATLQAEKQALKTQLKQLE 1076
Cdd:COG1196 766 ERELERLEREI----EALGPV---NllaieeyEELEERYDFLSEQREDLE 808
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
485-812 |
9.10e-18 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 90.50 E-value: 9.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 485 SVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLR----------ENLERQIK 554
Cdd:TIGR02168 671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlarleaevEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 555 LLEQENERSNQTIASLRQRSQiSAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEM----EHYKEKAERAEEL 630
Cdd:TIGR02168 751 QLSKELTELEAEIEELEERLE-EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtllnEEAANLRERLESL 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 631 ENELHHLEKENELLQKKIANLSitcEKIEALEKENSDLDIENRKLKKTLDSLKN-----------LSFQLESLEKENSQL 699
Cdd:TIGR02168 830 ERRIAATERRLEDLEEQIEELS---EDIESLAAEIEELEELIEELESELEALLNerasleealalLRSELEELSEELREL 906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 700 DEENLELRRRIESSKctsIKMAQLQLENKELESEKEQLKKSL-ELMKASFkksERLEVSYQGLDTENQRLQKALENSNKK 778
Cdd:TIGR02168 907 ESKRSELRRELEELR---EKLAQLELRLEGLEVRIDNLQERLsEEYSLTL---EEAEALENKIEDDEEEARRRLKRLENK 980
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2024492573 779 IQQL-------EGELQDLESENQTLQKNLEELVISSKRLEQ 812
Cdd:TIGR02168 981 IKELgpvnlaaIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
586-1113 |
4.71e-17 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 87.79 E-value: 4.71e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 586 EKENKILHEsiketssKLNKLEFEIKQVRKEMEHYKEKAERAEELENEL-----HHLEKENEL--LQKKIANLSitcEKI 658
Cdd:PRK02224 198 EKEEKDLHE-------RLNGLESELAELDEEIERYEEQREQARETRDEAdevleEHEERREELetLEAEIEDLR---ETI 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 659 EALEKENSDLDIENRKLKKTLDSLKNL-----------SFQLESLEKENSQLDEENLELRRRIESSKcTSIKMAqlqleN 727
Cdd:PRK02224 268 AETEREREELAEEVRDLRERLEELEEErddllaeagldDADAEAVEARREELEDRDEELRDRLEECR-VAAQAH-----N 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 728 KELESEKEqlkkslelmkasfkKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLE----EL 803
Cdd:PRK02224 342 EEAESLRE--------------DADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGdapvDL 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 804 VISSKRLEQLEKENKLLEQETSQLEKDKKQLEK---ENKRLRQQA-------EIKDS----TLEENNVKINHLEKENKSL 869
Cdd:PRK02224 408 GNAEDFLEELREERDELREREAELEATLRTARErveEAEALLEAGkcpecgqPVEGSphveTIEEDRERVEELEAELEDL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 870 FKQIAVYKESCVR---LKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELE-------KIGLNK 939
Cdd:PRK02224 488 EEEVEEVEERLERaedLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEekreaaaEAEEEA 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 940 ERLLCDEQSSDDRYKLLESKLES--TLKKSLEIKEEKIAALEA---RLEESTNLNQQLRQELKTVKKNYEALKQRQEEER 1014
Cdd:PRK02224 568 EEAREEVAELNSKLAELKERIESleRIRTLLAAIADAEDEIERlreKREALAELNDERRERLAEKRERKRELEAEFDEAR 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1015 MvqnppprkgEENQSvnkwEKENQETTREllKVKDRLIEVERNNATLQAEKQALKTQLKQLET---QNNNLQAQILALQr 1091
Cdd:PRK02224 648 I---------EEARE----DKERAEEYLE--QVEEKLDELREERDDLQAEIGAVENELEELEElreRREALENRVEALE- 711
|
570 580
....*....|....*....|..
gi 2024492573 1092 qtvSLQEQNTTLQTQNAKLQVE 1113
Cdd:PRK02224 712 ---ALYDEAEELESMYGDLRAE 730
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
252-848 |
6.23e-17 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 87.43 E-value: 6.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 252 LADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLlsdarsarvyRDELDILREKairVDKLESEVGRY 331
Cdd:PRK03918 167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEI----------SSELPELREE---LEKLEKEVKEL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 332 KERlhdmefyKARVEELMEDNQVMLETKRMFEDQVKTLQCRSDKlhvvekenlqLKAKLHEMEmERDMDRKKIEELMEEN 411
Cdd:PRK03918 234 EEL-------KEEIEELEKELESLEGSKRKLEEKIRELEERIEE----------LKKEIEELE-EKVKELKELKEKAEEY 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 412 MALEMAQKQSMDESLHLGWELEQINrftdhSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDsvggnSS 491
Cdd:PRK03918 296 IKLSEFYEEYLDELREIEKRLSRLE-----EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHEL-----YE 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 492 RIVKMEKENQRLNKKIEELEKEIVQEKQslqdnqnlsKDLMKEKEQLEKKfetlRENLERQIKLLEQENERSNQTIASLR 571
Cdd:PRK03918 366 EAKAKKEELERLKKRLTGLTPEKLEKEL---------EELEKAKEEIEEE----ISKITARIGELKKEIKELKKAIEELK 432
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 572 ----------------QRSQISAE--AQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRkEMEHYKEKAERAEELENE 633
Cdd:PRK03918 433 kakgkcpvcgrelteeHRKELLEEytAELKRIEKELKEIEEKERKLRKELRELEKVLKKES-ELIKLKELAEQLKELEEK 511
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 634 LHHLEKEnELLQKKianlsitcEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESS 713
Cdd:PRK03918 512 LKKYNLE-ELEKKA--------EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL 582
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 714 KCTSIKMAQLQLEN---------------KELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKalENSNKK 778
Cdd:PRK03918 583 GFESVEELEERLKElepfyneylelkdaeKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK--KYSEEE 660
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 779 IQQLEGELQDLESENQTLQKNLEELvisSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Cdd:PRK03918 661 YEELREEYLELSRELAGLRAELEEL---EKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELR 727
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
656-1379 |
7.25e-17 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 87.33 E-value: 7.25e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 656 EKIEALEKENSDLDIENRKLKKTLDSLKNLSFQlESLEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKE 735
Cdd:pfam02463 173 EALKKLIEETENLAELIIDLEELKLQELKLKEQ-AKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 736 QLKKSLELMKASFKKSERLEVSyqgLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEK 815
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKE---NKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 816 ENKLLEQETSQLEKdkkqLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVK 895
Cdd:pfam02463 329 ELKKEKEEIEELEK----ELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 896 RASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLKKSLEIKEEKI 975
Cdd:pfam02463 405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 976 AALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVE 1055
Cdd:pfam02463 485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1056 ----------RNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNT-----TLQTQNAKLQVENSTLNSQ 1120
Cdd:pfam02463 565 klvraltelpLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKrakvvEGILKDTELTKLKESAKAK 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1121 STSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYdSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKD 1200
Cdd:pfam02463 645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQE-LQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1201 LEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNN 1280
Cdd:pfam02463 724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1281 SKLGQTQLEAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR 1360
Cdd:pfam02463 804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQK 883
|
730
....*....|....*....
gi 2024492573 1361 QYIDKLNELRRQKEKLEEK 1379
Cdd:pfam02463 884 LKDELESKEEKEKEEKKEL 902
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
369-1159 |
1.11e-16 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 87.02 E-value: 1.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 369 LQCRSDKLHVVEKENLQLKAKLHEMEMerdmDRKKIEELMEENMALEMAQKQsmdeslhlgweleqinRFTDHSEVSHKS 448
Cdd:TIGR00606 233 LESSREIVKSYENELDPLKNRLKEIEH----NLSKIMKLDNEIKALKSRKKQ----------------MEKDNSELELKM 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 449 LglEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGgnssrivKMEKENQRLNKKIEELEKEI--VQEKQSLQDNQN 526
Cdd:TIGR00606 293 E--KVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELE-------KLNKERRLLNQEKTELLVEQgrLQLQADRHQEHI 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 527 LSKDLMKEKEQLEKKFETLREN--LERQIK----LLEQENERSNQTIASL---RQRSQISAEAQMKEIEKENKILHESIK 597
Cdd:TIGR00606 364 RARDSLIQSLATRLELDGFERGpfSERQIKnfhtLVIERQEDEAKTAAQLcadLQSKERLKQEQADEIRDEKKGLGRTIE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 598 ETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKkiaNLSITCEKIEALEKENSDLDIENRKLK- 676
Cdd:TIGR00606 444 LKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEK---NSLTETLKKEVKSLQNEKADLDRKLRKl 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 677 ----KTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESS-------------------------KCTSIKMAQLQLEN 727
Cdd:TIGR00606 521 dqemEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEltsllgyfpnkkqledwlhskskeiNQTRDRLAKLNKEL 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 728 KELESEKEQLKKSLELMKASFKK-SERL--EVSYQGLDTENQRLQKALENSNKKIQQLEGE-------LQDLESENQTLQ 797
Cdd:TIGR00606 601 ASLEQNKNHINNELESKEEQLSSyEDKLfdVCGSQDEESDLERLKEEIEKSSKQRAMLAGAtavysqfITQLTDENQSCC 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 798 KNLEELVISSKRLEQ----LEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQI 873
Cdd:TIGR00606 681 PVCQRVFQTEAELQEfisdLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 874 AVYK---ESCVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERllcdeQSSD 950
Cdd:TIGR00606 761 QRLKndiEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEK-----QEKQ 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 951 DRYKLLESKLEsTLKKSLEIKEEKIAALEARLEE--------STNLNQ------QLRQELKTVKKNYEALKQRQEEERMV 1016
Cdd:TIGR00606 836 HELDTVVSKIE-LNRKLIQDQQEQIQHLKSKTNElkseklqiGTNLQRrqqfeeQLVELSTEVQSLIREIKDAKEQDSPL 914
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1017 QNPPPRKGEENQS-VNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKT-QLKQLETQNNNLQAQILALQRQTV 1094
Cdd:TIGR00606 915 ETFLEKDQQEKEElISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDdYLKQKETELNTVNAQLEECEKHQE 994
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 1095 SLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSL 1159
Cdd:TIGR00606 995 KINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKL 1059
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
18-163 |
3.16e-16 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 77.67 E-value: 3.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 18 LVTWVRTFGpLADENGTSLEeymtLVDGVFLNEVMLQINPKSTNRNVNKRVNNDES----LRIQNLCILVKKIKYFYQEC 93
Cdd:cd22222 4 LLQWLQTFN-LIAPHATAED----LSDGVAIAQVLNQIDPEYFSDSWLSKIKPDVGdnwrLKVSNLKKILKGIVDYYSEV 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 94 L-QQLIVMALPNVLIIGRNplSEPgtNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEV 163
Cdd:cd22222 79 LgQQISGFTMPDVNAIAEK--EDP--KELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
556-1300 |
4.23e-16 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 84.78 E-value: 4.23e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 556 LEQENERSNQTIASLRQRSQISAEAQmkeiEKENKILHESIKETSSKLNKLEFEikqvRKEMEHYKEKAERAEE-----L 630
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELH----EKQKFYLRQSVIDLQTKLQEMQME----RDAMADIRRRESQSQEdlrnqL 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 631 ENELHHLEKENELLQKKIANLSITCEKIEAL---------EKENSDLDIENRKLKKTL--DSLKNLSFQL--ESLEKENS 697
Cdd:pfam15921 148 QNTVHELEAAKCLKEDMLEDSNTQIEQLRKMmlshegvlqEIRSILVDFEEASGKKIYehDSMSTMHFRSlgSAISKILR 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 698 QLDEENLELRRRIesskctsikmaqLQLENkELESEKEQLKKSLELMkasfkkserlevsyqgLDTENQRLQKALENSNK 777
Cdd:pfam15921 228 ELDTEISYLKGRI------------FPVED-QLEALKSESQNKIELL----------------LQQHQDRIEQLISEHEV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 778 KIQQLEGELQDLESENQTLQKNLEELVISSKR-----LEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTL 852
Cdd:pfam15921 279 EITGLTEKASSARSQANSIQSQLEIIQEQARNqnsmyMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 853 EENNVKINHLEKENKSLFKQI-AVYKESCVRLKELEME---NKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKL 928
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLqKLLADLHKREKELSLEkeqNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 929 SHELEKIGLNKERLLCDEQSSDDRYKLLESKLEST---LKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVK-KNYE 1004
Cdd:pfam15921 439 KSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEaTNAE 518
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1005 ALKQRQEEERMVQNPPPRKGEENQSVNKweKENQETTRELLKVKDRLIEVER----NNATLQAEKQ----ALKTQLKQLE 1076
Cdd:pfam15921 519 ITKLRSRVDLKLQELQHLKNEGDHLRNV--QTECEALKLQMAEKDKVIEILRqqieNMTQLVGQHGrtagAMQVEKAQLE 596
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1077 TQNNNLQaqiLALQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLY 1156
Cdd:pfam15921 597 KEINDRR---LELQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNEL 669
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1157 DSLLKDHEKLEHLHERQASEYESLIAK-HGSLKSAHKNLEVEHKDLEDR--------------YSQLLKQKVQLEELEKV 1221
Cdd:pfam15921 670 NSLSEDYEVLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMegsdghamkvamgmQKQITAKRGQIDALQSK 749
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 1222 LKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKLGQTQLEAEFSKLREEYQ 1300
Cdd:pfam15921 750 IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
701-1266 |
1.44e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.06 E-value: 1.44e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 701 EENL--------ELRRRIESSKctsiKMAQLQLENKELESEKEQLKKSLELMKasfkkserlevsYQGLDTENQRLQKAL 772
Cdd:COG1196 185 EENLerledilgELERQLEPLE----RQAEKAERYRELKEELKELEAELLLLK------------LRELEAELEELEAEL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 773 ENSNKKIQQLEGELQDLESENQTLQKNLEELvisSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTL 852
Cdd:COG1196 249 EELEAELEELEAELAELEAELEELRLELEEL---ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 853 EENNVKINHLEKENKSLFKQIAV----YKESCVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKL 928
Cdd:COG1196 326 AELEEELEELEEELEELEEELEEaeeeLEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 929 SHELEKIGLNKERLLcDEQSSDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQ 1008
Cdd:COG1196 406 EEAEEALLERLERLE-EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1009 RQEEERMVQNP--PPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLET--------- 1077
Cdd:COG1196 485 ELAEAAARLLLllEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDdevaaaaie 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1078 ---QNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKS 1154
Cdd:COG1196 565 ylkAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1155 LYDSLLKDHEKLEhlhERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNE 1234
Cdd:COG1196 645 RLREVTLEGEGGS---AGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721
|
570 580 590
....*....|....*....|....*....|..
gi 2024492573 1235 KHETVAAEYKKLRDENDRLAHTHDQLLKENEV 1266
Cdd:COG1196 722 EEEALEEQLEAEREELLEELLEEEELLEEEAL 753
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
256-1100 |
1.89e-15 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 82.79 E-value: 1.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 256 KAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDELDILREKAIRVDKLESEVGRYKErl 335
Cdd:TIGR00606 216 KEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKME-- 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 336 hdmEFYKARVEELMEDNQVMLETKRMFEDQVKTLQCRSDKLHvveKENLQLKAKLHEMEMERDMDRKKIEELMEENMAle 415
Cdd:TIGR00606 294 ---KVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLN---KERRLLNQEKTELLVEQGRLQLQADRHQEHIRA-- 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 416 maqKQSMDESLHLGWELEQINR--FTDHSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRI 493
Cdd:TIGR00606 366 ---RDSLIQSLATRLELDGFERgpFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTI 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 494 ----VKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSK-----------DLMKEKEQLEKKFETLRENLERQIKLLEQ 558
Cdd:TIGR00606 443 elkkEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKaerelskaeknSLTETLKKEVKSLQNEKADLDRKLRKLDQ 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 559 ENERSNQTIASLRQ-----RSQISAEAQMKEIEKENKILHESI-------KETSSKLNKLEFEIKQVRKEMEHYKEKAER 626
Cdd:TIGR00606 523 EMEQLNHHTTTRTQmemltKDKMDKDEQIRKIKSRHSDELTSLlgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELAS 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 627 AEELEnelHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEEN--- 703
Cdd:TIGR00606 603 LEQNK---NHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENqsc 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 704 -------LELRRRI-ESSKCTSIKMAQLQLENKELESEKEQLKKSLELM--KASFKKSE---------RLEVSYQGLDTE 764
Cdd:TIGR00606 680 cpvcqrvFQTEAELqEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMlgLAPGRQSIidlkekeipELRNKLQKVNRD 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 765 NQRLQKALENSNKKIQQLEGELQ---DLESENQTLQKNLEELVISSKRLEQL--EKENKLLEQETSQLEKDKKQLEKENK 839
Cdd:TIGR00606 760 IQRLKNDIEEQETLLGTIMPEEEsakVCLTDVTIMERFQMELKDVERKIAQQaaKLQGSDLDRTVQQVNQEKQEKQHELD 839
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 840 RLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLRED---LVNEKL 916
Cdd:TIGR00606 840 TVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQdspLETFLE 919
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 917 KTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRY-KLLESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQE 995
Cdd:TIGR00606 920 KDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYmKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINED 999
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 996 LKTVKKNYEALKQRqeeERMVQNPPPRKGEENQSvnkweKENQETTRELLKV--KDRLIEVERNNATLQAEKQALKTQLK 1073
Cdd:TIGR00606 1000 MRLMRQDIDTQKIQ---ERWLQDNLTLRKRENEL-----KEVEEELKQHLKEmgQMQVLQMKQEHQKLEENIDLIKRNHV 1071
|
890 900
....*....|....*....|....*..
gi 2024492573 1074 QLETQNNNLQAQILALQRQTVSLQEQN 1100
Cdd:TIGR00606 1072 LALGRQKGYEKEIKHFKKELREPQFRD 1098
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
240-1014 |
3.17e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 82.04 E-value: 3.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 240 KHTESKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLL-SDARSARVYRDEL-DILREK 317
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLeRSIAEK 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 318 AIRVDKLESEVGRYKERLHDmefYKARVEELMEDnqvmLETKRMFEDQVKT-LQCRSDKLHVVEKENLQLKAKLHEMEME 396
Cdd:TIGR02169 314 ERELEDAEERLAKLEAEIDK---LLAEIEELERE----IEEERKRRDKLTEeYAELKEELEDLRAELEEVDKEFAETRDE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 397 RDMDRKKIEELMEENMALEMAQKQSMDESLHLGWELEQINRftdhsevSHKSLGLEVTELTSSRLLKLEKenqslLKTVE 476
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNA-------AIAGIEAKINELEEEKEDKALE-----IKKQE 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 477 ELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQ---EKQSLQDNQNLSKDLMKE-KEQLEKKFETLRENL--- 549
Cdd:TIGR02169 455 WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEaeaQARASEERVRGGRAVEEVlKASIQGVHGTVAQLGsvg 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 550 ERQIKLLE------------QENERSNQTIASLRQRSQISAE----AQMKEIEKENKILHESiKETSSKLNKLEFE---- 609
Cdd:TIGR02169 535 ERYATAIEvaagnrlnnvvvEDDAVAKEAIELLKRRKAGRATflplNKMRDERRDLSILSED-GVIGFAVDLVEFDpkye 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 610 ---------------IKQVRKEMEHYkekaeRAEELENEL----------HHLEKENELLQKKI-ANLSITCEKIEALEK 663
Cdd:TIGR02169 614 pafkyvfgdtlvvedIEAARRLMGKY-----RMVTLEGELfeksgamtggSRAPRGGILFSRSEpAELQRLRERLEGLKR 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 664 ENSDLDIENRKLKKTLDSL----KNLSFQLESLEKENSQLDEENLELRRRIESSKctsIKMAQLQLENKELESEKEQLKK 739
Cdd:TIGR02169 689 ELSSLQSELRRIENRLDELsqelSDASRKIGEIEKEIEQLEQEEEKLKERLEELE---EDLSSLEQEIENVKSELKELEA 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 740 SLELMKASFKKserlevsyqgldtenqrLQKALEN-----SNKKIQQLEGELQDLESENQTLQKNLEELvisSKRLEQLE 814
Cdd:TIGR02169 766 RIEELEEDLHK-----------------LEEALNDlearlSHSRIPEIQAELSKLEEEVSRIEARLREI---EQKLNRLT 825
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 815 KENKLLEQETSQLEKDKKQLEKENKRLRQQaeikdstLEENNVKINHLEKEnkslfkqiavykescvrLKELEMENKELV 894
Cdd:TIGR02169 826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKE-------IENLNGKKEELEEE-----------------LEELEAALRDLE 881
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 895 KRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLkkSLEIKEEK 974
Cdd:TIGR02169 882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL--SLEDVQAE 959
|
810 820 830 840
....*....|....*....|....*....|....*....|...
gi 2024492573 975 IAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQ---EEER 1014
Cdd:TIGR02169 960 LQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRaklEEER 1002
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
384-999 |
3.39e-15 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 81.33 E-value: 3.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 384 LQLKAKLHEMEMERDMDRKKIE---ELMEENMALEMAQKQSMDESLHLGWELEQINRFTDHSEVSHKSLGLEVTELTSsr 460
Cdd:pfam05557 12 SQLQNEKKQMELEHKRARIELEkkaSALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALN-- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 461 llKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLskdlmkeKEQLEK 540
Cdd:pfam05557 90 --KKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQL-------RQNLEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 541 KFETLRENlERQIKLLEQENERSNQTIASLRQRSqiSAEAQMKEIEKENKILHESIKetssKLNKLEFEIKQVRKEMEHY 620
Cdd:pfam05557 161 QQSSLAEA-EQRIKELEFEIQSQEQDSEIVKNSK--SELARIPELEKELERLREHNK----HLNENIENKLLLKEEVEDL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 621 KEKAERAEELENELHHLEKENELLQKK-------IANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNlsfQLESLE 693
Cdd:pfam05557 234 KRKLEREEKYREEAATLELEKEKLEQElqswvklAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTS---SARQLE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 694 KENSQLDEENLELRRRIEsskctsikmaQLQLENKELESEKEQLKKSLELMKasfKKSERLEVSYQGLDTEnqrlqKALE 773
Cdd:pfam05557 311 KARRELEQELAQYLKKIE----------DLNKKLKRHKALVRRLQRRVLLLT---KERDGYRAILESYDKE-----LTMS 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 774 NSNKKIQQLEGELQDLESENQTLQKNLEelvissKRLEQLEKENKLLEQETSqlekdkkQLEKENKRLRQQAEIKDSTLE 853
Cdd:pfam05557 373 NYSPQLLERIEEAEDMTQKMQAHNEEME------AQLSVAEEELGGYKQQAQ-------TLERELQALRQQESLADPSYS 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 854 ENNV-----KINHLEKENKSLFKQIAVYkescvrlkELEMENKELVKRASIDKKTLVTLREDLVNEklKTQQMNNDLEKL 928
Cdd:pfam05557 440 KEEVdslrrKLETLELERQRLREQKNEL--------EMELERRCLQGDYDPKKTKVLHLSMNPAAE--AYQQRKNQLEKL 509
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 929 SHELEKIglnKERLLCDEQSSDDRYKLLESKLESTLKKSLEIKEEkIAALEARLEESTNLNQQLRQELKTV 999
Cdd:pfam05557 510 QAEIERL---KRLLKKLEDDLEQVLRLPETTSTMNFKEVLDLRKE-LESAELKNQRLKEVFQAKIQEFRDV 576
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
505-1233 |
4.30e-15 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 81.73 E-value: 4.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 505 KKIEELEK-EIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQ---ENERSNQTIASLRQRSQISAEA 580
Cdd:PTZ00121 1188 RKAEELRKaEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaEEERNNEEIRKFEEARMAHFAR 1267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 581 QMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAE---RAEELENELHHLEKENELLQKKIANLSITCEK 657
Cdd:PTZ00121 1268 RQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 658 IEALEKENSDlDIENRKLKKTLDSLKNLSFQLESLE-KENSQLDEENLELRRRIESSKCTSIKMAQLQLENK---ELESE 733
Cdd:PTZ00121 1348 AKAEAEAAAD-EAEAAEEKAEAAEKKKEEAKKKADAaKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKkadEAKKK 1426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 734 KEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQtLQKNLEELVISSKRLEQL 813
Cdd:PTZ00121 1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE-AKKKAEEAKKKADEAKKA 1505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 814 EKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKEL 893
Cdd:PTZ00121 1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE 1585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 894 VKRASiDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEkigLNKERLLCDEQSSDDRYKLLESKLESTLKKSLEIKEE 973
Cdd:PTZ00121 1586 AKKAE-EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE---LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKI 1661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 974 KIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIE 1053
Cdd:PTZ00121 1662 KAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1054 VERNNATLQAEKQAlKTQLKQLETQNNNLQAQILALQRQTVslqEQNTTLQTQNAKLQVENSTLNSQSTSlmnqnaqlli 1133
Cdd:PTZ00121 1742 DKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKEAVI---EEELDEEDEKRRMEVDKKIKDIFDNF---------- 1807
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1134 qQSALENEKEGVLKeLEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKV 1213
Cdd:PTZ00121 1808 -ANIIEGGKEGNLV-INDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIE 1885
|
730 740
....*....|....*....|
gi 2024492573 1214 QLEELEKVLKTEQEKMLQQN 1233
Cdd:PTZ00121 1886 EADEIEKIDKDDIEREIPNN 1905
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
495-1244 |
7.67e-15 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 80.54 E-value: 7.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 495 KMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQI---KLLEQENERSNQTIASLR 571
Cdd:pfam05483 82 KLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIqenKDLIKENNATRHLCNLLK 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 572 QRSQISAEaQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYK-EKAERAEELENELHHLEKEnelLQKKIAN 650
Cdd:pfam05483 162 ETCARSAE-KTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARlEMHFKLKEDHEKIQHLEEE---YKKEIND 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 651 L--SITCEKIEALEKENSdldienrklkktldsLKNLSFQLESLEKENSQLDEENlelrrriesskctsikmaQLQLEN- 727
Cdd:pfam05483 238 KekQVSLLLIQITEKENK---------------MKDLTFLLEESRDKANQLEEKT------------------KLQDENl 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 728 KELESEKEQLKKSLELMKASFKKSerleVSYQglDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISS 807
Cdd:pfam05483 285 KELIEKKDHLTKELEDIKMSLQRS----MSTQ--KALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATT 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 808 KRLEQLEK-ENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKEScvrlKEL 886
Cdd:pfam05483 359 CSLEELLRtEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIA----EEL 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 887 EMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKiglnkERLLCDEQSSDDRYKLLESKlestlkk 966
Cdd:pfam05483 435 KGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEK-----EKLKNIELTAHCDKLLLENK------- 502
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 967 sleikeekiaaleARLEESTNLNQQLRQELKTVKKNyealkqRQEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLK 1046
Cdd:pfam05483 503 -------------ELTQEASDMTLELKKHQEDIINC------KKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDE 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1047 VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAklqVENSTLNSQSTSLMN 1126
Cdd:pfam05483 564 VKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGS---AENKQLNAYEIKVNK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1127 QNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEK-------------------------LEHLHERQASEYESLI 1181
Cdd:pfam05483 641 LELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKakaiadeavklqkeidkrcqhkiaeMVALMEKHKHQYDKII 720
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024492573 1182 AKHGSLKSAHKNLEVEHKD----LEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYK 1244
Cdd:pfam05483 721 EERDSELGLYKNKEQEQSSakaaLEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
275-844 |
1.56e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 79.70 E-value: 1.56e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 275 DYKQELERVETELRRLQQENKNLLSDARSARVYRDELDILRekaiRVDKLESEVGRYKERLHDMEFYKARVEELMEDNQV 354
Cdd:PRK02224 166 EYRERASDARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHE----RLNGLESELAELDEEIERYEEQREQARETRDEADE 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 355 MLETKRMfedqvktlqcRSDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEMAQKQSMDESlhlgwELEQ 434
Cdd:PRK02224 242 VLEEHEE----------RREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEA-----GLDD 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 435 INRftdhsevshkslglevtELTSSRLLKLEKENQSLLKTVEELR---STMDDSVGGNSSRIVKMEKENQRLNKKIEELE 511
Cdd:PRK02224 307 ADA-----------------EAVEARREELEDRDEELRDRLEECRvaaQAHNEEAESLREDADDLEERAEELREEAAELE 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 512 KEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFE---TLRENLERQIKLLEQENERSNQTIASLRQRSQiSAEAQMKEIEK- 587
Cdd:PRK02224 370 SELEEAREAVEDRREEIEELEEEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLR-TARERVEEAEAl 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 588 -------------ENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEEL---ENELHHLEKENELLQKKIAN- 650
Cdd:PRK02224 449 leagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLveaEDRIERLEERREDLEELIAEr 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 651 ---LSITCEKIEALEKENSDLDIE------------------NRKLKKTLDSLKNLSFQLESLEKENSQLDEENlELRRR 709
Cdd:PRK02224 529 retIEEKRERAEELRERAAELEAEaeekreaaaeaeeeaeeaREEVAELNSKLAELKERIESLERIRTLLAAIA-DAEDE 607
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 710 IESSKCTSIKMAQLQLENKELESEKEQLKKSLElmkASFkKSERLEvsyqGLDTENQRLQKALENSNKKIQQLEGELQDL 789
Cdd:PRK02224 608 IERLREKREALAELNDERRERLAEKRERKRELE---AEF-DEARIE----EAREDKERAEEYLEQVEEKLDELREERDDL 679
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 790 ESENQTLQKNLEELVISSKRLEQLEKENKLLE---QETSQLEKDKKQLEKEnkrLRQQ 844
Cdd:PRK02224 680 QAEIGAVENELEELEELRERREALENRVEALEalyDEAEELESMYGDLRAE---LRQR 734
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
239-1014 |
4.44e-14 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 78.47 E-value: 4.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 239 LKHTESKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSA---------RVYRD 309
Cdd:pfam02463 232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEElksellkleRRKVD 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 310 ELDILREKAIRVDKLESEVGRYKERLHDMEFYKARVEELMEDNQVMLETKRMFEDQVKTLQCRSDKLHVVEKENLQLKAK 389
Cdd:pfam02463 312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 390 LHEMEME-RDMDRKKIEELMEENMALEMAQKQSMDESLHLGWELEQINRF--TDHSEVSHKSLGLEVTELTSSRLLKLEK 466
Cdd:pfam02463 392 LKEEELElKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELkqGKLTEEKEELEKQELKLLKDELELKKSE 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 467 ENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLR 546
Cdd:pfam02463 472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIV 551
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 547 ENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAER 626
Cdd:pfam02463 552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKD 631
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 627 AEELENELHHLEKENELLQKKIANLSITcekiealekensdldieNRKLKKTLDSLKNLSFQLESLEKENSQLDEENLEL 706
Cdd:pfam02463 632 TELTKLKESAKAKESGLRKGVSLEEGLA-----------------EKSEVKASLSELTKELLEIQELQEKAESELAKEEI 694
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 707 RRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGEL 786
Cdd:pfam02463 695 LRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEK 774
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 787 QDLESENQTLQKNLEELVISSKRLEQLEKENKLleqetSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKEN 866
Cdd:pfam02463 775 ELAEEREKTEKLKVEEEKEEKLKAQEEELRALE-----EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 867 KSLFKQIAVYKESCV----RLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERL 942
Cdd:pfam02463 850 KLAEEELERLEEEITkeelLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEI 929
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 943 LCDEQSSDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEAL---KQRQEEER 1014
Cdd:pfam02463 930 LLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDeleKERLEEEK 1004
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
275-573 |
1.59e-13 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 75.50 E-value: 1.59e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 275 DYKQELERVETELRRLQQENKNLLSDARSARVYRDELDILREKAIRVDKLESEVGRYKERLHDMEFYKARVEELMEDNQV 354
Cdd:pfam05622 84 DYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDILRESSDKVKKLEATVETYKKKLEDLGDLRRQVKLLEERNAE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 355 MLETKRMFEDQVK---------------------TLQCRSDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMA 413
Cdd:pfam05622 164 YMQRTLQLEEELKkanalrgqletykrqvqelhgKLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTLRETNEE 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 414 LEMAQKQSMdeslhlgwELEQINRFTDHSEVSHKSLGLEVTEL-TSSRLLKLEKENQSLLKTVE--------ELRSTMDD 484
Cdd:pfam05622 244 LRCAQLQQA--------ELSQADALLSPSSDPGDNLAAEIMPAeIREKLIRLQHENKMLRLGQEgsyrerltELQQLLED 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 485 SvggnSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSN 564
Cdd:pfam05622 316 A----NRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELEP 391
|
....*....
gi 2024492573 565 QTIASLRQR 573
Cdd:pfam05622 392 KQDSNLAQK 400
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
18-163 |
1.65e-13 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 69.74 E-value: 1.65e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 18 LVTWVRTFGPLADENgtSLEEymtLVDGVFLNEVMLQINPKSTNRNVNKRVNNDES----LRIQNLCILVKKIKYFYQEC 93
Cdd:pfam19047 6 LLTWLQTFNVPAPCA--TVED---LTDGVAMAQVLHQIDPSWFTEAWLSRIKEDVGdnwrLKVSNLKKILQSVVDYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 94 L-QQLIVMALPNVLIIGRNplSEPGtnEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEV 163
Cdd:pfam19047 81 LgQQISDFLLPDVNLIGEH--SDPA--ELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
246-918 |
4.38e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 4.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 246 QHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELR--RLQQENKNLLSDARSARvyrdeldiLREKAIRVDK 323
Cdd:COG1196 228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEelRLELEELELELEEAQAE--------EYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 324 LESEVGRYKERLHDMEfykARVEELMEDnqvmletkrmfedqvktlqcrsdkLHVVEKENLQLKAKLHEMEMERDMDRKK 403
Cdd:COG1196 300 LEQDIARLEERRRELE---ERLEELEEE------------------------LAELEEELEELEEELEELEEELEEAEEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 404 IEELmeENMALEMAQKQSMDESLHLGWELEQINRftdhsevshkslglevteltSSRLLKLEKENQSLLKTVEELRSTMD 483
Cdd:COG1196 353 LEEA--EAELAEAEEALLEAEAELAEAEEELEEL--------------------AEELLEALRAAAELAAQLEELEEAEE 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 484 DsvggNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERS 563
Cdd:COG1196 411 A----LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 564 NQtiASLRQRSQISAEAQMKEIEKENKILHESIketssKLNKLEFEIKQVRKEmEHYKEKAERAEELENELHHLEKENEL 643
Cdd:COG1196 487 AE--AAARLLLLLEAEADYEGFLEGVKAALLLA-----GLRGLAGAVAVLIGV-EAAYEAALEAALAAALQNIVVEDDEV 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 644 LQKKIANLSitcekiEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKCTSIKMAQL 723
Cdd:COG1196 559 AAAAIEYLK------AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 724 QLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEEl 803
Cdd:COG1196 633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE- 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 804 visskRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQI----AV---- 875
Cdd:COG1196 712 -----AEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIealgPVnlla 786
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 876 ---YKESCVRLKELEMENKELVKR--------ASIDKKTLVTLRE--DLVNEKLKT 918
Cdd:COG1196 787 ieeYEELEERYDFLSEQREDLEEAretleeaiEEIDRETRERFLEtfDAVNENFQE 842
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
245-1000 |
7.52e-13 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 74.38 E-value: 7.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 245 KQHLSVELADAKAKIRRLRQEIEEKNE----QFLDYKQELERVETELRRLQQEnKNLLSDARSaRVYRDELDILREKAIR 320
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNElhekQKFYLRQSVIDLQTKLQEMQME-RDAMADIRR-RESQSQEDLRNQLQNT 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 321 VDKLESEVGRYKERLHDMEFYKARVEELMEDNQVMLETKRM----FEDQVKTLQCRSDKLHVVEKENL--QLKAKLHEME 394
Cdd:pfam15921 151 VHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSilvdFEEASGKKIYEHDSMSTMHFRSLgsAISKILRELD 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 395 MERDMDRKKIEELMEENMALEMAQKQSMDesLHLGWELEQINRFTDHSEVSHKSLGLEVTELTSS--------RLLKLEK 466
Cdd:pfam15921 231 TEISYLKGRIFPVEDQLEALKSESQNKIE--LLLQQHQDRIEQLISEHEVEITGLTEKASSARSQansiqsqlEIIQEQA 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 467 ENQS--LLKTVEELRSTMddsvggnsSRIVKMEKENQRL-NKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFE 543
Cdd:pfam15921 309 RNQNsmYMRQLSDLESTV--------SQLRSELREAKRMyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 544 TLRENLERQIKLLEQENERsNQTIASLRQRSQISAEAQMKEIEKENKilheSIKETSSKLNKLEFEIK-QVRKEMEHYKE 622
Cdd:pfam15921 381 KLLADLHKREKELSLEKEQ-NKRLWDRDTGNSITIDHLRRELDDRNM----EVQRLEALLKAMKSECQgQMERQMAAIQG 455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 623 KAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDI----ENRKLKKTLDSLKNLSFQLESLEKENSQ 698
Cdd:pfam15921 456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAslqeKERAIEATNAEITKLRSRVDLKLQELQH 535
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 699 LDEENLELRRriESSKCTSIKMaQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTE--NQRLQ----KAL 772
Cdd:pfam15921 536 LKNEGDHLRN--VQTECEALKL-QMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEinDRRLElqefKIL 612
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 773 EN-SNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQlEKENKLLEQETSQLEKDKKQLEKE--NKRLRQQAEIKD 849
Cdd:pfam15921 613 KDkKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQ-ERDQLLNEVKTSRNELNSLSEDYEvlKRNFRNKSEEME 691
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 850 STLEENNVKINHLEKE---NKSLFKQIAVYKESCVRLKeLEMENKELVKRASID--KKTLVTLREDLVNEKLKTQQMNND 924
Cdd:pfam15921 692 TTTNKLKMQLKSAQSEleqTRNTLKSMEGSDGHAMKVA-MGMQKQITAKRGQIDalQSKIQFLEEAMTNANKEKHFLKEE 770
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 925 LEKLSHELEKIGLNKERLLCDEQ---SSDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVK 1000
Cdd:pfam15921 771 KNKLSQELSTVATEKNKMAGELEvlrSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
245-986 |
2.02e-12 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 72.45 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 245 KQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYrdeldilrekairVDKL 324
Cdd:pfam05483 94 KVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHL-------------CNLL 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 325 ESEVGRYKERLHDMEFykarveELMEDNQVMLETKRMFEDQVKTLQCRSdklhvVEKENLQLkaklhEMEMERDMDRKKI 404
Cdd:pfam05483 161 KETCARSAEKTKKYEY------EREETRQVYMDLNNNIEKMILAFEELR-----VQAENARL-----EMHFKLKEDHEKI 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 405 EELmEENMALEMAQKQSmDESLHLGWELEQINRFTDHSEVSHKSLGL-----EVTELTSSRLLKLEKENQSLLKTVEELR 479
Cdd:pfam05483 225 QHL-EEEYKKEINDKEK-QVSLLLIQITEKENKMKDLTFLLEESRDKanqleEKTKLQDENLKELIEKKDHLTKELEDIK 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 480 STMDDSVGGNSSrivkMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEkeqlekkFETLRENLERQIKLLEQE 559
Cdd:pfam05483 303 MSLQRSMSTQKA----LEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTE-------FEATTCSLEELLRTEQQR 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 560 NERSNQTIASLRQrsqisaeaqmkEIEKENKILHESIKETSSKLNKLEfEIKQVRKEMEHYKEKAERAEELENELHHLEK 639
Cdd:pfam05483 372 LEKNEDQLKIITM-----------ELQKKSSELEEMTKFKNNKEVELE-ELKKILAEDEKLLDEKKQFEKIAEELKGKEQ 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 640 ENELLqkkianlsitcekIEALEKENSDLDIEnrkLKKTLDSLKNLSFQLESLEKENSQLDEENLELrrrieSSKCTsik 719
Cdd:pfam05483 440 ELIFL-------------LQAREKEIHDLEIQ---LTAIKTSEEHYLKEVEDLKTELEKEKLKNIEL-----TAHCD--- 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 720 maQLQLENKELESEKE----QLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQ-DLESENQ 794
Cdd:pfam05483 496 --KLLLENKELTQEASdmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKcKLDKSEE 573
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 795 TLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKE---NKSLFK 871
Cdd:pfam05483 574 NARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELElasAKQKFE 653
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 872 QIAVYKESCVRLKELEMEN-KELVKRASIDKKTLVTLREDL-VNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSS 949
Cdd:pfam05483 654 EIIDNYQKEIEDKKISEEKlLEEVEKAKAIADEAVKLQKEIdKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNK 733
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 2024492573 950 DDRYKLLESKLES----------TLKKSLEIKEEKIAALEARLEEST 986
Cdd:pfam05483 734 EQEQSSAKAALEIelsnikaellSLKKQLEIEKEEKEKLKMEAKENT 780
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
261-1227 |
2.47e-12 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 72.52 E-value: 2.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 261 RLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSD-ARSARVYRDELDILREKAIRVDKLESEVGRYKERLHDME 339
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEkNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 340 fykARVEELMEDNQVMLETKRMFEDQVKTLQcrsdkLHVVEKENLQLKAKLHEMEMErdmdrKKIEELMEENMALEMAQK 419
Cdd:pfam01576 82 ---SRLEEEEERSQQLQNEKKKMQQHIQDLE-----EQLDEEEAARQKLQLEKVTTE-----AKIKKLEEDILLLEDQNS 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 420 QSMDESLHLGwelEQINRFTDHsevshkslgLEVTELTSSRLLKLEKENQSLLKTVEElrstmddsvggnssRIVKMEKE 499
Cdd:pfam01576 149 KLSKERKLLE---ERISEFTSN---------LAEEEEKAKSLSKLKNKHEAMISDLEE--------------RLKKEEKG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 500 NQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLmkeKEQLEKKFETLRENLERqiklLEQENERSNQTIASLRQ-RSQIS- 577
Cdd:pfam01576 203 RQELEKAKRKLEGESTDLQEQIAELQAQIAEL---RAQLAKKEEELQAALAR----LEEETAQKNNALKKIRElEAQISe 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 578 --------------AEAQMKEIEKENKILHESIKETSSKLN-------KLEFEIKQVRKEMEHYKE--KAERAEELENEL 634
Cdd:pfam01576 276 lqedleseraarnkAEKQRRDLGEELEALKTELEDTLDTTAaqqelrsKREQEVTELKKALEEETRshEAQLQEMRQKHT 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 635 HHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKL-----------KKTLDSLKNLSFQLESLEKENSQLDEEN 703
Cdd:pfam01576 356 QALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLqqakqdsehkrKKLEGQLQELQARLSESERQRAELAEKL 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 704 LELRRRIES-SKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQL 782
Cdd:pfam01576 436 SKLQSELESvSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNV 515
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 783 EGELQDLESENQTLQKNLEELVISSKRLEQ----LEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVK 858
Cdd:pfam01576 516 ERQLSTLQAQLSDMKKKLEEDAGTLEALEEgkkrLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQL 595
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 859 INHLEKENKSLFKQIAVYKESCVRLKE----LEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEK 934
Cdd:pfam01576 596 VSNLEKKQKKFDQMLAEEKAISARYAEerdrAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDD 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 935 IGLNKERLlcdEQSSddryKLLESKLESTLKKSLEIKEEKIAALEARLEESTN---LNQQLRQELKTV-----KKNYEAL 1006
Cdd:pfam01576 676 VGKNVHEL---ERSK----RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNmqaLKAQFERDLQARdeqgeEKRRQLV 748
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1007 KQRQEEERMVQNPPPRKGEENQSVNKWE--------------KENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQL 1072
Cdd:pfam01576 749 KQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaqidaanKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQS 828
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1073 KQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEgvlKELEDL 1152
Cdd:pfam01576 829 KESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELE---EEQSNT 905
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1153 KSLYDSLLKDHEKLEHLHERQASEYESLiakhGSLKSAHKNLEVEHKDLEDRYSQL-----LKQKVQLEELE-KVLKTEQ 1226
Cdd:pfam01576 906 ELLNDRLRKSTLQVEQLTTELAAERSTS----QKSESARQQLERQNKELKAKLQEMegtvkSKFKSSIAALEaKIAQLEE 981
|
.
gi 2024492573 1227 E 1227
Cdd:pfam01576 982 Q 982
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
256-657 |
3.17e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.40 E-value: 3.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 256 KAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARvyrdelDILREKAIRVDKLESEVGRYKERL 335
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS------RQISALRKDLARLEAEVEQLEERI 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 336 HDMEFYKARVEELMEDNQVMLETKRmfedqvktlqcrsDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEEnmale 415
Cdd:TIGR02168 750 AQLSKELTELEAEIEELEERLEEAE-------------EELAEAEAEIEELEAQIEQLKEELKALREALDELRAE----- 811
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 416 maqkqsmdeslhlgweleqinrftdhsevsHKSLGLEVTELTsSRLLKLEKENQSLLKTVEELRSTMDDsvggNSSRIVK 495
Cdd:TIGR02168 812 ------------------------------LTLLNEEAANLR-ERLESLERRIAATERRLEDLEEQIEE----LSEDIES 856
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 496 MEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLREN---LERQIKLLEQENERSNQTIASLRQ 572
Cdd:TIGR02168 857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKrseLRRELEELREKLAQLELRLEGLEV 936
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 573 R-----SQISAEAQM--KEIEKENKILHESIKETSSKLNKLEFEIKQV----RKEMEHYKEKAERAEELENELHHLEKEN 641
Cdd:TIGR02168 937 RidnlqERLSEEYSLtlEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnLAAIEEYEELKERYDFLTAQKEDLTEAK 1016
|
410
....*....|....*.
gi 2024492573 642 ELLQKKIANLSITCEK 657
Cdd:TIGR02168 1017 ETLEEAIEEIDREARE 1032
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
483-1169 |
5.91e-12 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 71.41 E-value: 5.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 483 DDSVGGNSSRIVKMEKEN-----------QRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLER 551
Cdd:pfam12128 208 DDGVVPPKSRLNRQQVEHwirdiqaiagiMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAE 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 552 QIKLLEQENERSNQTIASLRQrsqisaeaqmkeiekENKILHESIKETSSKLNKLEFEIKQVRKE-MEHYKEKAERAEEL 630
Cdd:pfam12128 288 LNQLLRTLDDQWKEKRDELNG---------------ELSAADAAVAKDRSELEALEDQHGAFLDAdIETAAADQEQLPSW 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 631 ENELHHLEKENELLQKKIANLSITCEKIEALEKEN-----SDLDIENRKLKKTLDSLKNL-SFQLESLEKE-NSQLDEEN 703
Cdd:pfam12128 353 QSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnnrdiAGIKDKLAKIREARDRQLAVaEDDLQALESElREQLEAGK 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 704 LELRRRIESSKcTSIKMAQLQLENKELESE-KEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQL 782
Cdd:pfam12128 433 LEFNEEEYRLK-SRLGELKLRLNQATATPElLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQA 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 783 EGELQDLESENQTLQKNLEELviSSKRLEQLEKENKLLEQ------ETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENN 856
Cdd:pfam12128 512 SRRLEERQSALDELELQLFPQ--AGTLLHFLRKEAPDWEQsigkviSPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKR 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 857 VKINHLEKENKSLFKQIAVYKESCVRLKELEME-NKELVK-RASIDK--KTLVTLREDLVNEKLKTQQMNNDLEKLSHEL 932
Cdd:pfam12128 590 IDVPEWAASEEELRERLDKAEEALQSAREKQAAaEEQLVQaNGELEKasREETFARTALKNARLDLRRLFDEKQSEKDKK 669
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 933 EKIGLNKERLLCDE-QSSDDRYKLLESKLESTLKKSLEIKEE-KIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQ 1010
Cdd:pfam12128 670 NKALAERKDSANERlNSLEAQLKQLDKKHQAWLEEQKEQKREaRTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAEL 749
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1011 EE-ERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVER----NNATLQAEKQALKTQLKQLETQNNNLQAQ 1085
Cdd:pfam12128 750 KAlETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRyfdwYQETWLQRRPRLATQLSNIERAISELQQQ 829
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1086 ilaLQRQTVSLQEQNTTLQTQ---NAKLQVENSTLNSQSTSLMNQNAQLLIQQSA--LENEKEGVLKELEDLKSLYDSLL 1160
Cdd:pfam12128 830 ---LARLIADTKLRRAKLEMErkaSEKQQVRLSENLRGLRCEMSKLATLKEDANSeqAQGSIGERLAQLEDLKLKRDYLS 906
|
730
....*....|
gi 2024492573 1161 KDHEK-LEHL 1169
Cdd:pfam12128 907 ESVKKyVEHF 916
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
957-1282 |
7.16e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.12 E-value: 7.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 957 ESKLESTlkksleikEEKIAALEARLEEstnLNQQLRQeLK---TVKKNYEALKQRQEEermvqnpppRKGEEnqSVNKW 1033
Cdd:COG1196 178 ERKLEAT--------EENLERLEDILGE---LERQLEP-LErqaEKAERYRELKEELKE---------LEAEL--LLLKL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1034 ---EKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA-------QILALQRQTVSLQEQNTTL 1103
Cdd:COG1196 235 relEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRREL 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1104 QTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAK 1183
Cdd:COG1196 315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1184 HGSLKSAHKNLEVEHKDLEDRYSQLLKQKvqlEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKE 1263
Cdd:COG1196 395 AAELAAQLEELEEAEEALLERLERLEEEL---EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
|
330
....*....|....*....
gi 2024492573 1264 NEVLQTDHKNLKTLLNNSK 1282
Cdd:COG1196 472 AALLEAALAELLEELAEAA 490
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
752-1326 |
7.30e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 70.86 E-value: 7.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 752 ERLEVSYQGLDTENQRLQKALENSNKKIQQlEGELQDLESEN-QTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKD 830
Cdd:PRK03918 158 DDYENAYKNLGEVIKEIKRRIERLEKFIKR-TENIEELIKEKeKELEEVLREINEISSELPELREELEKLEKEVKELEEL 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 831 KKQLEKENKRLRQQaEIKDSTLEEnnvKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKrasidkktlvtLRED 910
Cdd:PRK03918 237 KEEIEELEKELESL-EGSKRKLEE---KIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK-----------LSEF 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 911 LVNEKLKTQQMNNDLEKLSHELEKIglnkERLLCDEQSSDDRYKLLESKLESTLKKSLEIKE-----EKIAALEARLE-- 983
Cdd:PRK03918 302 YEEYLDELREIEKRLSRLEEEINGI----EERIKELEEKEERLEELKKKLKELEKRLEELEErhelyEEAKAKKEELErl 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 984 --ESTNLN-QQLRQELKTVKKNYEAL-KQRQEEERMVQNPPPRKGEENQSVNKWEKEN-------------------QET 1040
Cdd:PRK03918 378 kkRLTGLTpEKLEKELEELEKAKEEIeEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgrelteehrkellEEY 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1041 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLET--QNNNLQAQILALQRQTVSLQ--------EQNTTLQTQNAKL 1110
Cdd:PRK03918 458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNleelekkaEEYEKLKEKLIKL 537
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1111 QVENSTLNSQSTSLmnqnaqlliqqSALENEKEGVLKELEDLKSLYDSLLKDHEKL-----EHLHERqASEYESLIAKHG 1185
Cdd:PRK03918 538 KGEIKSLKKELEKL-----------EELKKKLAELEKKLDELEEELAELLKELEELgfesvEELEER-LKELEPFYNEYL 605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1186 SLKSAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKtEQEKMLQQNEKHETVaAEYKKLRDENDRLAHTHDQLLKENE 1265
Cdd:PRK03918 606 ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE-ELRKELEELEKKYSE-EEYEELREEYLELSRELAGLRAELE 683
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 1266 VLQTDHKNLKTLLNNSKlgqTQLEaEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEE 1326
Cdd:PRK03918 684 ELEKRREEIKKTLEKLK---EELE-EREKAKKELEKLEKALERVEELREKVKKYKALLKER 740
|
|
| HkD_Hook3 |
cd22226 |
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein ... |
18-163 |
1.13e-11 |
|
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook3 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411797 Cd Length: 153 Bit Score: 64.60 E-value: 1.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 18 LVTWVRTFGplADENGTSLEEymtLVDGVFLNEVMLQINP----KSTNRNVNKRVNNDESLRIQNLCILVKKIKYFYQEC 93
Cdd:cd22226 9 LLTWIQTFN--VDAPCQTVED---LTSGVVMAQVLQKIDPayfdENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 94 L-QQLIVMALPNVLIIGRNPlsepGTNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEV 163
Cdd:cd22226 84 LgQQINDFTLPDVNLIGEHS----DAAELGRMLQLILGCAVNCEQKQEYIQTIMMMEESVQHVVMTAIQEL 150
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
555-1269 |
1.20e-11 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 70.49 E-value: 1.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 555 LLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKILhESIKETSSKLNKLEFEIKQVRKEM-EHYKEKAERAEELENE 633
Cdd:COG5022 782 RLRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSYLACI-IKLQKTIKREKKLRETEEVEFSLKaEVLIQKFGRSLKAKKR 860
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 634 LHHLEKENELLQKKianlsitcEKIEALEKENSDLDIENRKLkktlDSLKNLsfqleslekeNSQLDEENLELRRRIESS 713
Cdd:COG5022 861 FSLLKKETIYLQSA--------QRVELAERQLQELKIDVKSI----SSLKLV----------NLELESEIIELKKSLSSD 918
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 714 KctsikMAQLQLENKELESEKE-----QLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQD 788
Cdd:COG5022 919 L-----IENLEFKTELIARLKKllnniDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSE 993
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 789 LESENQTLQK---NLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKrlrQQAEIKDSTLEEN----NVKINH 861
Cdd:COG5022 994 LKNFKKELAElskQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKP---LQKLKGLLLLENNqlqaRYKALK 1070
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 862 LEKENKSLFK------QIAVYKESCVRLKELEMENKELVKRASIDKKTL-VTLREDLVNEKLK--------TQQMNNDLE 926
Cdd:COG5022 1071 LRRENSLLDDkqlyqlESTENLLKTINVKDLEVTNRNLVKPANVLQFIVaQMIKLNLLQEISKflsqlvntLEPVFQKLS 1150
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 927 KLSHELEKIG--LNKERLLC----DEQSSDDRYKLLESKLESTLKKS-LEIKEEKIAALeARLEESTNLNQQLRQELKTV 999
Cdd:COG5022 1151 VLQLELDGLFweANLEALPSpppfAALSEKRLYQSALYDEKSKLSSSeVNDLKNELIAL-FSKIFSGWPRGDKLKKLISE 1229
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1000 KKNYEALKQRQEEERMVQNPPPRKgeenqsvnkwEKENQETTRELLKVKDRLIEVErnnatlQAEKQALKTQLKQLETQN 1079
Cdd:COG5022 1230 GWVPTEYSTSLKGFNNLNKKFDTP----------ASMSNEKLLSLLNSIDNLLSSY------KLEEEVLPATINSLLQYI 1293
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1080 NNLQAQILALQRqtvslqeqnttlqtqnaklqvenSTLNSQSTSLMNQNAQLLIQQSaLENEKEGVLKELEDLKSLYDSL 1159
Cdd:COG5022 1294 NVGLFNALRTKA-----------------------SSLRWKSATEVNYNSEELDDWC-REFEISDVDEELEELIQAVKVL 1349
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1160 LKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKdledrysqlLKQKVQLEELEKVLKTEQEKMLQQNEKHETV 1239
Cdd:COG5022 1350 QLLKDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKENN---------LPKEILKKIEALLIKQELQLSLEGKDETEVH 1420
|
730 740 750
....*....|....*....|....*....|
gi 2024492573 1240 AAEykkLRDENDRLAHTHDQLLKENEVLQT 1269
Cdd:COG5022 1421 LSE---IFSEEKSLISLDRNSIYKEEVLSS 1447
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
625-1009 |
1.70e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 69.41 E-value: 1.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 625 ERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKtLDSLKNLSFQLESLEKENSQLDEENL 704
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK-LLQLLPLYQELEALEAELAELPERLE 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 705 ELRRRIESskctsikMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVsyqgldtenQRLQKALENSNKKIQQLEG 784
Cdd:COG4717 150 ELEERLEE-------LRELEEELEELEAELAELQEELEELLEQLSLATEEEL---------QDLAEELEELQQRLAELEE 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 785 ELQDLESENQTLQKNLEELVISSKRLEQLEKENKL--------------------------------------------L 820
Cdd:COG4717 214 ELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallallglggsllsliltiagvlflvlgllallfllL 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 821 EQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESC---------VRLKELEMENK 891
Cdd:COG4717 294 AREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLreaeeleeeLQLEELEQEIA 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 892 ELVKRASIDKKTLVTLREDLVNEKlktQQMNNDLEKLSHELEKIGLNKERLLC--DEQSSDDRYKLLESKLEStLKKSLE 969
Cdd:COG4717 374 ALLAEAGVEDEEELRAALEQAEEY---QELKEELEELEEQLEELLGELEELLEalDEEELEEELEELEEELEE-LEEELE 449
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 2024492573 970 IKEEKIAALEARLE--ESTNLNQQLRQELKTVKKNYEALKQR 1009
Cdd:COG4717 450 ELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEE 491
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
286-937 |
1.96e-11 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 69.55 E-value: 1.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 286 ELRRLQQENKNLLSDARSARVYRDELDILREKAIRVDKLESEVGRYkerlhdmefykarVEELMEDNQVMLETKRMFEDQ 365
Cdd:PRK01156 150 QRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSS-------------NLELENIKKQIADDEKSHSIT 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 366 VKTLQCRSDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEMaqkqsmdeslhlgwELEQINRFTDHSEvs 445
Cdd:PRK01156 217 LKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSM--------------ELEKNNYYKELEE-- 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 446 hkslglEVTELTSSRLLKLEKENQSLLKTVEELRStMDDSVGGNSSRIVKMEKenqrLNKKIEELEKEIVQ--EKQSLQD 523
Cdd:PRK01156 281 ------RHMKIINDPVYKNRNYINDYFKYKNDIEN-KKQILSNIDAEINKYHA----IIKKLSVLQKDYNDyiKKKSRYD 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 524 NQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKilheSIKETSSKL 603
Cdd:PRK01156 350 DLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINV----KLQDISSKV 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 604 NKLEFEIKQVRkemEHYKEKAERAEELENEL------HHL--EKENELLQKKIANLSITCEKIEALEKENSDLDIENRKL 675
Cdd:PRK01156 426 SSLNQRIRALR---ENLDELSRNMEMLNGQSvcpvcgTTLgeEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDL 502
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 676 KKTLDSLKnlSFQLESLEKENSQLDeenlELRRRIESSKCTSIKMAQLQLENKELESEKEQLKksLELMKASFKKSERLE 755
Cdd:PRK01156 503 KKRKEYLE--SEEINKSINEYNKIE----SARADLEDIKIKINELKDKHDKYEEIKNRYKSLK--LEDLDSKRTSWLNAL 574
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 756 VSYQGLDTENQRLQ-----KALENSNKKIQQLEGELQDLESENQTLQKNLEElvisskRLEQLEKENKLLEQETSQLEKD 830
Cdd:PRK01156 575 AVISLIDIETNRSRsneikKQLNDLESRLQEIEIGFPDDKSYIDKSIREIEN------EANNLNNKYNEIQENKILIEKL 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 831 KKQLEKENKRLRQQAEIKDStLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDkktlVTLRED 910
Cdd:PRK01156 649 RGKIDNYKKQIAEIDSIIPD-LKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDR----INDINE 723
|
650 660
....*....|....*....|....*..
gi 2024492573 911 LVNEKLKTQQMNNDLEKLSHELEKIGL 937
Cdd:PRK01156 724 TLESMKKIKKAIGDLKRLREAFDKSGV 750
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
451-1194 |
2.56e-11 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 69.70 E-value: 2.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 451 LEVTELTSSRLLKLeKENQSLLKtvEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKeiVQEKQSLQDNQNLSKD 530
Cdd:TIGR01612 923 IKICENTKESIEKF-HNKQNILK--EILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDK--AFKDASLNDYEAKNNE 997
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 531 LMKEKEQLEKKFETLRENL--------ERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKE---------NKILH 593
Cdd:TIGR01612 998 LIKYFNDLKANLGKNKENMlyhqfdekEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEigkniellnKEILE 1077
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 594 ES---------IKET-----------------SSKLNKLEFEIKQVRKEMEHY-KEKAERAEELENELHHLEKENELLQK 646
Cdd:TIGR01612 1078 EAeinitnfneIKEKlkhynfddfgkeenikyADEINKIKDDIKNLDQKIDHHiKALEEIKKKSENYIDEIKAQINDLED 1157
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 647 kIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDE------------ENLELRRRIESSK 714
Cdd:TIGR01612 1158 -VADKAISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEvkginlsygknlGKLFLEKIDEEKK 1236
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 715 CTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEV---------SYQGLDTENQRLQKALENSNKKIQQLEGE 785
Cdd:TIGR01612 1237 KSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETfnishdddkDHHIISKKHDENISDIREKSLKIIEDFSE 1316
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 786 LQDLESENQTLQKNLEElvisskrleqLEKENKLLEQETSQLEKDKKQLeKENKRLRQQAEIKDST--LEENNVKINHLE 863
Cdd:TIGR01612 1317 ESDINDIKKELQKNLLD----------AQKHNSDINLYLNEIANIYNIL-KLNKIKKIIDEVKEYTkeIEENNKNIKDEL 1385
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 864 KENKSLFKQIA--VYKESCVRLKELEMENKEL---VKRASIDKKTLVTlREDLVNEKLKTQQMNNDLEKLSHELEKIGLN 938
Cdd:TIGR01612 1386 DKSEKLIKKIKddINLEECKSKIESTLDDKDIdecIKKIKELKNHILS-EESNIDTYFKNADENNENVLLLFKNIEMADN 1464
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 939 KERLLC----DEQSSDDRYKLLEskLESTLKKSLEIKEEKIAALEArLEESTNLNQQLRQELKTVKKNYEALKQRQEEER 1014
Cdd:TIGR01612 1465 KSQHILkikkDNATNDHDFNINE--LKEHIDKSKGCKDEADKNAKA-IEKNKELFEQYKKDVTELLNKYSALAIKNKFAK 1541
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1015 MVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQA---LKTQLKQLETQN---NNLQAQILA 1088
Cdd:TIGR01612 1542 TKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAaidIQLSLENFENKFlkiSDIKKKIND 1621
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1089 LQRQTVSLQEQNTTLQ--TQNAKLQVENSTLNSQST---SLMNQNAQLLIQQSALENekegVLKELEDLKSLYDSLLKDH 1163
Cdd:TIGR01612 1622 CLKETESIEKKISSFSidSQDTELKENGDNLNSLQEfleSLKDQKKNIEDKKKELDE----LDSEIEKIEIDVDQHKKNY 1697
|
810 820 830
....*....|....*....|....*....|...
gi 2024492573 1164 E--KLEHLHERQASEYESLIAKHGSLKSAHKNL 1194
Cdd:TIGR01612 1698 EigIIEKIKEIAIANKEEIESIKELIEPTIENL 1730
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
240-685 |
2.90e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 69.40 E-value: 2.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 240 KHTESKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDELDILREKAI 319
Cdd:PTZ00121 1349 KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE 1428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 320 RVDKLE-----SEVGRYKERLHDMEFYKARVEELM---EDNQVMLETKRMFEDQVKTLQCRSdKLHVVEKENLQLKAKLH 391
Cdd:PTZ00121 1429 EKKKADeakkkAEEAKKADEAKKKAEEAKKAEEAKkkaEEAKKADEAKKKAEEAKKADEAKK-KAEEAKKKADEAKKAAE 1507
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 392 EM----EMERDMDRKKIEEL--MEENMALEMAQKQsmdESLHLGWELEQINRFTDHSEVSHKSLGLEVTELTSSRLLKLE 465
Cdd:PTZ00121 1508 AKkkadEAKKAEEAKKADEAkkAEEAKKADEAKKA---EEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 466 KENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLN--KKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFE 543
Cdd:PTZ00121 1585 EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA 1664
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 544 TLRENLERQIKLLEQ----ENERSNQTIASLRQRSQISAEAQMKEIEKENKILHESIKEtSSKLNKLEFEikQVRKEMEH 619
Cdd:PTZ00121 1665 EEAKKAEEDKKKAEEakkaEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK-AEEENKIKAE--EAKKEAEE 1741
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 620 YKEKAERA---EELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNL 685
Cdd:PTZ00121 1742 DKKKAEEAkkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANI 1810
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1039-1378 |
3.23e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.81 E-value: 3.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1039 ETTRE-LLKVKDRLIEVERNNATL--QAEK----QALKTQLKQLEtqnnnlqAQILALQRQTVSLQeqnttLQTQNAKLQ 1111
Cdd:COG1196 182 EATEEnLERLEDILGELERQLEPLerQAEKaeryRELKEELKELE-------AELLLLKLRELEAE-----LEELEAELE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1112 VENSTLNSQSTSLMNQNAQLLIQQSALENEKEgvlkELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAH 1191
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELEL----ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1192 KNLEVEHKDLEDrysQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDH 1271
Cdd:COG1196 326 AELEEELEELEE---ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1272 KNLKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKCTKISNQcellsqlkgnmEEENRHLLDQIQTLMLQNRTLLEQNMES 1351
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA-----------LEEAAEEEAELEEEEEALLELLAELLEE 471
|
330 340
....*....|....*....|....*..
gi 2024492573 1352 KDLFHVEQRQYIDKLNELRRQKEKLEE 1378
Cdd:COG1196 472 AALLEAALAELLEELAEAAARLLLLLE 498
|
|
| HkD_Hook2 |
cd22227 |
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a ... |
18-163 |
4.64e-11 |
|
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a microtubule-binding protein that contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook2 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411798 Cd Length: 150 Bit Score: 62.97 E-value: 4.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 18 LVTWVRTFGPLAdengtSLEEYMTLVDGVFLNEVMLQINPKSTNRNVNKRVNNDES----LRIQNLCILVKKIKYFYQEC 93
Cdd:cd22227 6 LLTWLQTFQVPS-----PCSSYQDLTSGVAIAQVLNRIDPSWFNEAWLGRIKEDTGdnwrLKVSNLKKILQSLLEYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 94 L-QQLIVMALPNVLIIGRnpLSEPgtNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEV 163
Cdd:cd22227 81 LgHQVSEDHLPDVNLIGE--FSDD--TELGKLLQLVLGCAISCEKKQEHIQQIMTLEESVQHVVMEAIQEL 147
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
455-849 |
4.90e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 67.87 E-value: 4.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 455 ELTSSRLLKLEKENQSLLKTVEELRsTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEK--QSLQDNQNLSKDLM 532
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYA-ELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 533 KEKEQLEKKFETLREnLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQ 612
Cdd:COG4717 146 ERLEELEERLEELRE-LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 613 VRKEMEHYKEKAERAEELEN------------ELHHLEKENELLQKKIAN----------LSITCEKIEALEKENSDLDI 670
Cdd:COG4717 225 LEEELEQLENELEAAALEERlkearlllliaaALLALLGLGGSLLSLILTiagvlflvlgLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 671 ENRKLKKTLDSLKNLSFQ--LESLEKENSQLDEENLELRRRIES--SKCTSIKMAQLQLENKELESEKEQLKKSLEL-MK 745
Cdd:COG4717 305 EELQALPALEELEEEELEelLAALGLPPDLSPEELLELLDRIEElqELLREAEELEEELQLEELEQEIAALLAEAGVeDE 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 746 ASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQL--EGELQDLESENQTLQKNLEELvisSKRLEQLEKENKLLEQE 823
Cdd:COG4717 385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELleALDEEELEEELEELEEELEEL---EEELEELREELAELEAE 461
|
410 420
....*....|....*....|....*.
gi 2024492573 824 TSQLEKDKKQLEKENKRLRQQAEIKD 849
Cdd:COG4717 462 LEQLEEDGELAELLQELEELKAELRE 487
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
258-664 |
5.38e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 67.87 E-value: 5.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 258 KIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDELDI----------LREKAIRVDKLESE 327
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqelealeaeLAELPERLEELEER 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 328 VGRYKERLHDMEFYKARVEELMED-NQVMLETKRMFEDQVKTLQcrsDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEE 406
Cdd:COG4717 155 LEELRELEEELEELEAELAELQEElEELLEQLSLATEEELQDLA---EELEELQQRLAELEEELEEAQEELEELEEELEQ 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 407 LMEENMALEMAQKQSMDESLHLG----WELEQINRFTDHSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTM 482
Cdd:COG4717 232 LENELEAAALEERLKEARLLLLIaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALP 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 483 D-------------DSVGGNSSR-------IVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKF 542
Cdd:COG4717 312 AleeleeeeleellAALGLPPDLspeelleLLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAAL 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 543 etlrENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYkE 622
Cdd:COG4717 392 ----EQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL-E 466
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 2024492573 623 KAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKE 664
Cdd:COG4717 467 EDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREE 508
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
656-901 |
7.12e-11 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 66.33 E-value: 7.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 656 EKIEALEKENSDLDIENRKLKKTLDSLKNlsfQLESLEKENSQLDEENLELRRRIESskcTSIKMAQLQLENKELESEKE 735
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKK---EEKALLKQLAALERRIAALARRIRA---LEQELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 736 QLKKSLELMKASFkkSERLEVSYQgldtENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVissKRLEQLEK 815
Cdd:COG4942 94 ELRAELEAQKEEL--AELLRALYR----LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR---ADLAELAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 816 ENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVK 895
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
|
....*.
gi 2024492573 896 RASIDK 901
Cdd:COG4942 245 AAGFAA 250
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
213-838 |
7.50e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.86 E-value: 7.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 213 ELSEDRDSLHLLPQASAAQSPCGSPGLKHTESKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQ 292
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 293 ENKnllSDARSARVYRDEldilREKAIRVDKLESEvgRYKERLHDMEFYKARVEELMEDNQVMLETKRMFEDQVKTLQCR 372
Cdd:PTZ00121 1326 EAK---KKADAAKKKAEE----AKKAAEAAKAEAE--AAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 373 SDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEMAQKQSMDESLHLGWELEQINRFTDHSEVSHKSLGLE 452
Cdd:PTZ00121 1397 KKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK 1476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 453 VTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNK-----KIEELEK-EIVQEKQSLQDNQN 526
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaeeakKADEAKKaEEKKKADELKKAEE 1556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 527 LSKDLMKEKEQLEKKFETLRENLERQIKLLEQ-ENERSNQTIASLRQRSQISAEAQMKEIEKENKILH----ESIKETSS 601
Cdd:PTZ00121 1557 LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKaEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElkkaEEEKKKVE 1636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 602 KLNKLEFEIK----QVRKEMEHYKEKAE----RAEELENELHHLEKENELLQKKIANLsitceKIEALEKENSDldienr 673
Cdd:PTZ00121 1637 QLKKKEAEEKkkaeELKKAEEENKIKAAeeakKAEEDKKKAEEAKKAEEDEKKAAEAL-----KKEAEEAKKAE------ 1705
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 674 KLKKTLDSLKNLSFQLESLEKENSQLDEenlELRRRIESSKctsiKMAQlQLENKELESEKEQLKKSLELMKASFKKSER 753
Cdd:PTZ00121 1706 ELKKKEAEEKKKAEELKKAEEENKIKAE---EAKKEAEEDK----KKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEK 1777
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 754 LEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRlEQLEKENKLLEqETSQLEKDKKQ 833
Cdd:PTZ00121 1778 EAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK-EVADSKNMQLE-EADAFEKHKFN 1855
|
....*
gi 2024492573 834 LEKEN 838
Cdd:PTZ00121 1856 KNNEN 1860
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
500-1252 |
1.15e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.47 E-value: 1.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 500 NQRLN-KKIEEL-EKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQIS 577
Cdd:PTZ00121 1021 NQNFNiEKIEELtEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKA 1100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 578 AEAQMKEiekENKILHESIKETSSKLNKLEFEIKQVRKEMEHYK-EKAERAEElENELHHLEKENELLQKKIANLSITCE 656
Cdd:PTZ00121 1101 EEAKKTE---TGKAEEARKAEEAKKKAEDARKAEEARKAEDARKaEEARKAED-AKRVEIARKAEDARKAEEARKAEDAK 1176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 657 KIEALEKEnsdldIENRK---LKKTLDSLKnlsfQLESLEKENSQLDEEnleLRRRIESSKCTSIKMAQLQLENKELESE 733
Cdd:PTZ00121 1177 KAEAARKA-----EEVRKaeeLRKAEDARK----AEAARKAEEERKAEE---ARKAEDAKKAEAVKKAEEAKKDAEEAKK 1244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 734 KEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEElvisSKRLEQL 813
Cdd:PTZ00121 1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEE----AKKADEA 1320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 814 EKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEmenkEL 893
Cdd:PTZ00121 1321 KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD----EA 1396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 894 VKRASIDKKtlvtlREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLKKSLEikEE 973
Cdd:PTZ00121 1397 KKKAEEDKK-----KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE--EA 1469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 974 KIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPppRKGEENQSVNKWEKENQETTRELLKVKDrliE 1053
Cdd:PTZ00121 1470 KKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA--KKAEEAKKADEAKKAEEAKKADEAKKAE---E 1544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1054 VERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQstslMNQNAQLLI 1133
Cdd:PTZ00121 1545 KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE----AKKAEEAKI 1620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1134 QQSALENEKEgVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKV 1213
Cdd:PTZ00121 1621 KAEELKKAEE-EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE 1699
|
730 740 750 760
....*....|....*....|....*....|....*....|....
gi 2024492573 1214 QLEELEKVLKTEQEKM-----LQQNEKHETVAAEYKKLRDENDR 1252
Cdd:PTZ00121 1700 EAKKAEELKKKEAEEKkkaeeLKKAEEENKIKAEEAKKEAEEDK 1743
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1130 |
1.67e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 65.17 E-value: 1.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 917 KTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNLNQQLRQEL 996
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 997 KTVKKNYEALKQRQEeeRMVQNPPPRKGEENQSVNKWEKE-------NQETTRELLKVKDRLIEVERNNATLQAEKQALK 1069
Cdd:COG4942 100 EAQKEELAELLRALY--RLGRQPPLALLLSPEDFLDAVRRlqylkylAPARREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 1070 TQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ 1130
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
182-844 |
1.84e-10 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 66.30 E-value: 1.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 182 TQDSVEPLLKNMTLHLRRLVDERDEHLETIIELSEDRDSlhllpQASAAQSPCGSPGLKHTESKQHLSVELADAKAKIRR 261
Cdd:pfam15921 254 SQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARS-----QANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQ 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 262 LRQEIEEKNEQFLDYKQELErvetelRRLQQENKNlLSDARSARvyrdeldilrekairvDKLESEVGRYKERLHDM--E 339
Cdd:pfam15921 329 LRSELREAKRMYEDKIEELE------KQLVLANSE-LTEARTER----------------DQFSQESGNLDDQLQKLlaD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 340 FYKARVEELMEDNQvmleTKRMFEdqvktlqcrSDKLHVVEKENLQLKAKLHEMEMER-DMDRKKIEELMEENMALEMAQ 418
Cdd:pfam15921 386 LHKREKELSLEKEQ----NKRLWD---------RDTGNSITIDHLRRELDDRNMEVQRlEALLKAMKSECQGQMERQMAA 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 419 KQSMDESlhlgweLEQINRFTDHSEVSHKSLGLEVTELTSSRLLKLEKEnqsllKTVEELRSTMDDSVGGNSSRIVKMEK 498
Cdd:pfam15921 453 IQGKNES------LEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSE-----RTVSDLTASLQEKERAIEATNAEITK 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 499 ENQRLNKKIEELEkEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNqtiASLRQRSQISA 578
Cdd:pfam15921 522 LRSRVDLKLQELQ-HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAG---AMQVEKAQLEK 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 579 EAQMKEIE-KENKILHEsiketssklnklefeikqvrkemehykEKAERAEELENELHHLEKEnellqkKIANLSITCEK 657
Cdd:pfam15921 598 EINDRRLElQEFKILKD---------------------------KKDAKIRELEARVSDLELE------KVKLVNAGSER 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 658 IEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKensqldeenlELRRRIESSKCTSIKmaqLQLENKELESEKEQL 737
Cdd:pfam15921 645 LRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR----------NFRNKSEEMETTTNK---LKMQLKSAQSELEQT 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 738 KKSLELMKASFKKSERLEVSYQgldtenqrlqkalensnKKIQQLEGELQDLESENQTLQknlEELVISSKRLEQLEKEN 817
Cdd:pfam15921 712 RNTLKSMEGSDGHAMKVAMGMQ-----------------KQITAKRGQIDALQSKIQFLE---EAMTNANKEKHFLKEEK 771
|
650 660
....*....|....*....|....*..
gi 2024492573 818 KLLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam15921 772 NKLSQELSTVATEKNKMAGELEVLRSQ 798
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
770-1213 |
5.63e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.40 E-value: 5.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 770 KALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLE--KENKRLRQQAEI 847
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 848 KDS---TLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKElvKRASIDKKTLVTLREDLVNEKLKTQQMNND 924
Cdd:COG4717 144 LPErleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 925 LEKLSHELEKIGLNKERLLCDEQSSDDRYKLLeskLESTLkKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYE 1004
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLL---IAAAL-LALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1005 ALKQRQEEErmVQNPPPRKGEENQSVNKWEKE----NQETTRELLKVKDRLIEVERNNATLQAEKQALktQLKQLETQNN 1080
Cdd:COG4717 298 ASLGKEAEE--LQALPALEELEEEELEELLAAlglpPDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELEQEIA 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1081 NLQA-----------QILALQRQTVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLK 1147
Cdd:COG4717 374 ALLAeagvedeeelrAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELRE 453
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 1148 ELEDLKSLYDSLLKDHE--KLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKV 1213
Cdd:COG4717 454 ELAELEAELEQLEEDGElaELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERA 521
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
630-1079 |
7.79e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.02 E-value: 7.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 630 LENELHhlEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRR 709
Cdd:COG4717 47 LLERLE--KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 710 IESSKctsiKMAQLQLENKELESEKEQLKKslelMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKI-QQLEGELQD 788
Cdd:COG4717 125 LQLLP----LYQELEALEAELAELPERLEE----LEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQD 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 789 LESENQTLQKNLEELvisSKRLEQLEKENKLLEQETSQLEkDKKQLEKENKRLRQQAEI------------KDSTLEENN 856
Cdd:COG4717 197 LAEELEELQQRLAEL---EEELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLlliaaallallgLGGSLLSLI 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 857 VKI---------------NHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQM 921
Cdd:COG4717 273 LTIagvlflvlgllallfLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQEL 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 922 NNDLEKLSHELEKIGLNKERL-LCDEQSSDDRyKLLESKLEstLKKSLEIKEEKIAALEARLEESTNLNQ---------Q 991
Cdd:COG4717 353 LREAEELEEELQLEELEQEIAaLLAEAGVEDE-EELRAALE--QAEEYQELKEELEELEEQLEELLGELEellealdeeE 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 992 LRQELKTVKKNYEALKQRQEEERMvqnpppRKGEENQSVNKWEKEN--QETTRELLKVKDRLIEVERNNATLQAEKQALK 1069
Cdd:COG4717 430 LEEELEELEEELEELEEELEELRE------ELAELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLE 503
|
490
....*....|
gi 2024492573 1070 TQLKQLETQN 1079
Cdd:COG4717 504 EAREEYREER 513
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
473-858 |
9.31e-10 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 63.82 E-value: 9.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 473 KTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQE---KQSLQDNQNLSKDLMKEKEQLEKKFETLRENL 549
Cdd:COG5185 208 KESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSdklEKLVEQNTDLRLEKLGENAESSKRLNENANNL 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 550 ERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKEnkiLHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEE 629
Cdd:COG5185 288 IKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQE---LEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 630 LENELHHLEKENELLQKKIANLSITCEKIE-----ALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENL 704
Cdd:COG5185 365 NIVGEVELSKSSEELDSFKDTIESTKESLDeipqnQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLN 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 705 ELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEG 784
Cdd:COG5185 445 ELISELNKVMREADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAE 524
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024492573 785 ELQDLESENQTLQKnleelvisskrlEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVK 858
Cdd:COG5185 525 SLKDFMRARGYAHI------------LALENLIPASELIQASNAKTDGQAANLRTAVIDELTQYLSTIESQQAR 586
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
251-707 |
9.63e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 63.91 E-value: 9.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 251 ELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLS-------DARSARVYRDEL--------DILR 315
Cdd:PRK02224 252 ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAeaglddaDAEAVEARREELedrdeelrDRLE 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 316 EKAIRVDKLESEVGRYKERLHDMEFY-------KARVEELMEDNQVMLETKR----MFEDQVKTLQCRSDKLHvVEKENL 384
Cdd:PRK02224 332 ECRVAAQAHNEEAESLREDADDLEERaeelreeAAELESELEEAREAVEDRReeieELEEEIEELRERFGDAP-VDLGNA 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 385 Q--------LKAKLHEMEMERDMDRKKIEELMEENMALEMAQK-----QSMDESLH-------------LGWELEQInrf 438
Cdd:PRK02224 411 EdfleelreERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHvetieedrerveeLEAELEDL--- 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 439 tdhsEVSHKSLGLEVTELTSsrLLKLEKENQSLL---KTVEELRSTMDDSVGGNSSRIvkmekenQRLNKKIEELEKEIV 515
Cdd:PRK02224 488 ----EEEVEEVEERLERAED--LVEAEDRIERLEerrEDLEELIAERRETIEEKRERA-------EELRERAAELEAEAE 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 516 QEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSN--QTIASLRQRsqisaEAQMKEIEKENKilh 593
Cdd:PRK02224 555 EKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADaeDEIERLREK-----REALAELNDERR--- 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 594 ESIKETSSKLNKLEFEIKQVRkeMEHYKEKAERAEE----LENELHHLEKENELLQKKIANLSitcEKIEALEkensdld 669
Cdd:PRK02224 627 ERLAEKRERKRELEAEFDEAR--IEEAREDKERAEEyleqVEEKLDELREERDDLQAEIGAVE---NELEELE------- 694
|
490 500 510
....*....|....*....|....*....|....*...
gi 2024492573 670 ienrKLKKTLDSLKNLSFQLESLEKENSQLDEENLELR 707
Cdd:PRK02224 695 ----ELRERREALENRVEALEALYDEAEELESMYGDLR 728
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
495-854 |
1.09e-09 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 63.33 E-value: 1.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 495 KMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRE----NLERQIKLLEQENER-----SNQ 565
Cdd:pfam06160 7 KIYKEIDELEERKNELMNLPVQEELSKVKKLNLTGETQEKFEEWRKKWDDIVTkslpDIEELLFEAEELNDKyrfkkAKK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 566 TIASLRQRSQiSAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERA-EELENELHHLEKENELL 644
Cdd:pfam06160 87 ALDEIEELLD-DIEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTLLANRFSYGPAiDELEKQLAEIEEEFSQF 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 645 QKKIAN---------LSITCEKIEALEKENSDLDIENRKLKKTL-DSLKNLSFQLESLEKENSQLDEENLE-----LRRR 709
Cdd:pfam06160 166 EELTESgdylearevLEKLEEETDALEELMEDIPPLYEELKTELpDQLEELKEGYREMEEEGYALEHLNVDkeiqqLEEQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 710 IESSK--CTSIKMAQLQLENKELESEKEQLKKSLELMKASF----KKSERLEVSYQGLDTENQRLQKALENSNK------ 777
Cdd:pfam06160 246 LEENLalLENLELDEAEEALEEIEERIDQLYDLLEKEVDAKkyveKNLPEIEDYLEHAEEQNKELKEELERVQQsytlne 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 778 ----KIQQLEGELQDLESENQTLQKNLEELVIS----SKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Cdd:pfam06160 326 neleRVRGLEKQLEELEKRYDEIVERLEEKEVAyselQEELEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFK 405
|
....*
gi 2024492573 850 STLEE 854
Cdd:pfam06160 406 LELRE 410
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1035-1263 |
1.41e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 62.09 E-value: 1.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1035 KENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVEn 1114
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1115 stLNSQSTSLMNQ--NAQLLIQQSALEnekegVLKELEDLKSLYDSLlkdhEKLEHLHERQASEYESLIAKHGSLKSAHK 1192
Cdd:COG4942 99 --LEAQKEELAELlrALYRLGRQPPLA-----LLLSPEDFLDAVRRL----QYLKYLAPARREQAEELRADLAELAALRA 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 1193 NLEVEHKDLEDRYSQLLKQKVQLEElekvLKTEQEKMLQQ-NEKHETVAAEYKKLRDENDRLAHTHDQLLKE 1263
Cdd:COG4942 168 ELEAERAELEALLAELEEERAALEA----LKAERQKLLARlEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
499-835 |
1.58e-09 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 63.22 E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 499 ENQRLNKKIEelekeIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSnqtiASLRQRSQISA 578
Cdd:pfam17380 267 ENEFLNQLLH-----IVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQ----AEMDRQAAIYA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 579 EAQMKEIEKE---NKILHESIKETSSKLNKLEF--EIKQVRKEMEHYKEKAERAEELENELHHLEKEN---ELLQKKIAN 650
Cdd:pfam17380 338 EQERMAMERErelERIRQEERKRELERIRQEEIamEISRMRELERLQMERQQKNERVRQELEAARKVKileEERQRKIQQ 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 651 LSITCEKIEAlEKENSDlDIENRKLKKTLDSlknlsfQLESLEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKEL 730
Cdd:pfam17380 418 QKVEMEQIRA-EQEEAR-QREVRRLEEERAR------EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRA 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 731 ESEKEQ-LKKSLELMKASFKKSERlevSYQGLDTENQRLQKAL-ENSNKKIQQLEGELQDLESENQTLQKNLEELVISSK 808
Cdd:pfam17380 490 EEQRRKiLEKELEERKQAMIEEER---KRKLLEKEMEERQKAIyEEERRREAEEERRKQQEMEERRRIQEQMRKATEERS 566
|
330 340
....*....|....*....|....*..
gi 2024492573 809 RLEQLEKENKLLEQeTSQLEKDKKQLE 835
Cdd:pfam17380 567 RLEAMEREREMMRQ-IVESEKARAEYE 592
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
455-1012 |
1.65e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 1.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 455 ELTSSRLLKLEKENQSLLKTVEELRSTMDDSvggnSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKE 534
Cdd:COG1196 249 EELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 535 KEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKILHE---------SIKETSSKLNK 605
Cdd:COG1196 325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELaeellealrAAAELAAQLEE 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 606 LEFEIKQVRKEMEHYKE--KAERAEELENE------LHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKK 677
Cdd:COG1196 405 LEEAEEALLERLERLEEelEELEEALAELEeeeeeeEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 678 TLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSK---------------------CTSIKMAQLQLENKELESEKEQ 736
Cdd:COG1196 485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavavligveaayeaaleaALAAALQNIVVEDDEVAAAAIE 564
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 737 LKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENsnkkiqQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKE 816
Cdd:COG1196 565 YLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD------LVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 817 NKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEennvkinhlekenkslfkqiavykescvRLKELEMENKELVKR 896
Cdd:COG1196 639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL----------------------------EAEAELEELAERLAE 690
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 897 ASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLKKSLEIKEEKIA 976
Cdd:COG1196 691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
|
570 580 590
....*....|....*....|....*....|....*.
gi 2024492573 977 ALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEE 1012
Cdd:COG1196 771 RLEREIEALGPVNLLAIEEYEELEERYDFLSEQRED 806
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
726-1378 |
2.26e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 62.68 E-value: 2.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 726 ENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALE----NSNKKIQQLEGELQDLESENQTLQKNLE 801
Cdd:TIGR00618 164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPcmpdTYHERKQVLEKELKHLREALQQTQQSHA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 802 ELvissKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRL--------------------------RQQAEIKDSTLEEN 855
Cdd:TIGR00618 244 YL----TQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLeetqerinrarkaaplaahikavtqiEQQAQRIHTELQSK 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 856 NVKINHLEKENKSLFKQIAVYKESCVRLKELEME--------NKELVKRASIDKKTlvTLREDLvnekLKTQQMNNDLEK 927
Cdd:TIGR00618 320 MRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQeihirdahEVATSIREISCQQH--TLTQHI----HTLQQQKTTLTQ 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 928 LSHELEKIGLNKERLLCDEQSSDDRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTnlnQQLRQELKTVKKNYEALK 1007
Cdd:TIGR00618 394 KLQSLCKELDILQREQATIDTRTSAFRDLQGQL-AHAKKQQELQQRYAELCAAAITCTA---QCEKLEKIHLQESAQSLK 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1008 QRQEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKvKDRLIEVER----NNATLQAEKQALKTQLKQLETQNNNLQ 1083
Cdd:TIGR00618 470 EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCG-SCIHPNPARqdidNPGPLTRRMQRGEQTYAQLETSEEDVY 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1084 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDH 1163
Cdd:TIGR00618 549 HQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQ 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1164 EKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEH----KDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNE----K 1235
Cdd:TIGR00618 629 DVRLHLQQCSQELALKLTALHALQLTLTQERVREHalsiRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQtllrE 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1236 HETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKN---------LKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKC 1306
Cdd:TIGR00618 709 LETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKelmhqartvLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQ 788
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 1307 TKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNrtllEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEE 1378
Cdd:TIGR00618 789 FFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQC----ETLVQEEEQFLSRLEEKSATLGEITHQLLKYEE 856
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
663-1338 |
2.94e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 62.50 E-value: 2.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 663 KENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRriesskctsikmaQLQLENkELESEKEQLKKSLE 742
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQE-------------QLQAET-ELCAEAEEMRARLA 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 743 LMKASFKksERLEVSYQGLDTENQRLQkALENSNKKIQQLEGEL-QDLESENQTLQKNLEELVISSKRLEQLEKENKLLE 821
Cdd:pfam01576 68 ARKQELE--EILHELESRLEEEEERSQ-QLQNEKKKMQQHIQDLeEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLE 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 822 QETSQLEKDKKQLEKENKRLrqqaeikDSTLEENNVKINHLekeNKSLFKQIAVYKESCVRLKELEMENKELVKRASIDK 901
Cdd:pfam01576 145 DQNSKLSKERKLLEERISEF-------TSNLAEEEEKAKSL---SKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLE 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 902 KTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLeSTLKKSLEIK---------- 971
Cdd:pfam01576 215 GESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQI-SELQEDLESEraarnkaekq 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 972 ----EEKIAALEARLEE---STNLNQQLR----QELKTVKKNYEALKQRQE--------------EERMVQNPPPRKGEE 1026
Cdd:pfam01576 294 rrdlGEELEALKTELEDtldTTAAQQELRskreQEVTELKKALEEETRSHEaqlqemrqkhtqalEELTEQLEQAKRNKA 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1027 NQSVNK--WEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ 1104
Cdd:pfam01576 374 NLEKAKqaLESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAE 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1105 TQNAKLQVENSTLNSQStslmnQNAQLLIQQSALENEKEGV-LKELEDLKSLYDSLLKDHEKLEHLHERQASEYESliak 1183
Cdd:pfam01576 454 GKNIKLSKDVSSLESQL-----QDTQELLQEETRQKLNLSTrLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQA---- 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1184 hgSLKSAHKNLEVEHKDLEdrysqllkqkvQLEELEKVLKTEQEKMLQQNEKHetvAAEYKKLRDENDRLAHTHDQLLKE 1263
Cdd:pfam01576 525 --QLSDMKKKLEEDAGTLE-----------ALEEGKKRLQRELEALTQQLEEK---AAAYDKLEKTKNRLQQELDDLLVD 588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1264 NE-------VLQTDHKNLKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENRHLLDQIQT 1336
Cdd:pfam01576 589 LDhqrqlvsNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMED 668
|
..
gi 2024492573 1337 LM 1338
Cdd:pfam01576 669 LV 670
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
243-1380 |
3.00e-09 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 62.76 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 243 ESKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNlLSDARSarvyrdeldiLREKAIRVD 322
Cdd:TIGR01612 558 KLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKN-ISDKNE----------YIKKAIDLK 626
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 323 KLESEVGRYKERLHDMEFYKarVEELMEDNQVMLET-----KRMFEDQVKTLQcrsDKLHVVEKE----NLQLKAKLHEM 393
Cdd:TIGR01612 627 KIIENNNAYIDELAKISPYQ--VPEHLKNKDKIYSTikselSKIYEDDIDALY---NELSSIVKEnaidNTEDKAKLDDL 701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 394 EMERDMDRKKIEELMEENMALEMAQKQSMDESL---------HLGWEL-EQINRFTDHSEVSHKSLglevteltSSRLLK 463
Cdd:TIGR01612 702 KSKIDKEYDKIQNMETATVELHLSNIENKKNELldiiveikkHIHGEInKDLNKILEDFKNKEKEL--------SNKIND 773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 464 LEKENQSLLK---TVEELRSTMDDSVGGNSSRivkmEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEK 540
Cdd:TIGR01612 774 YAKEKDELNKyksKISEIKNHYNDQINIDNIK----DEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVD 849
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 541 KFETLRENLERQIklleqENERSNQTIASLRQRSQISAEaQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHY 620
Cdd:TIGR01612 850 KFINFENNCKEKI-----DSEHEQFAELTNKIKAEISDD-KLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVDEYI 923
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 621 KEKAERAEELENELHHLEKENELLQKKIANLSIT---------------CEKIEALEKENSDLDI-----ENRKLKKTLD 680
Cdd:TIGR01612 924 KICENTKESIEKFHNKQNILKEILNKNIDTIKESnlieksykdkfdntlIDKINELDKAFKDASLndyeaKNNELIKYFN 1003
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 681 SLKN---------LSFQLESLEKENSQLDEENLELRR---RIESSKCTSIKMAQLQLEN---KELESEKEQLKKSLELMK 745
Cdd:TIGR01612 1004 DLKAnlgknkenmLYHQFDEKEKATNDIEQKIEDANKnipNIEIAIHTSIYNIIDEIEKeigKNIELLNKEILEEAEINI 1083
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 746 ASFKKSERLEVSYQGLD----------TENQRLQKALENSNKKIQQLEGELQDL--ESEN-----QTLQKNLEELVISSK 808
Cdd:TIGR01612 1084 TNFNEIKEKLKHYNFDDfgkeenikyaDEINKIKDDIKNLDQKIDHHIKALEEIkkKSENyideiKAQINDLEDVADKAI 1163
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 809 RLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEI-KDST-LEE-NNVKINHLEKENKSLFKQIAVYK---ESCVR 882
Cdd:TIGR01612 1164 SNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIeKDKTsLEEvKGINLSYGKNLGKLFLEKIDEEKkksEHMIK 1243
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 883 LKELEMENKELVKRASIDKKTLVTLREDlVNEKLKTQQMNNDLEKLSHELEKIGlnkerllcDEQSSDDRYKLLESKLES 962
Cdd:TIGR01612 1244 AMEAYIEDLDEIKEKSPEIENEMGIEMD-IKAEMETFNISHDDDKDHHIISKKH--------DENISDIREKSLKIIEDF 1314
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 963 TLKKSL-EIKEEkiaaLEARLEESTNLNQQLRQELKTVKKNYEALKqrqeeermVQNPPPRKGEENQSVNKWEKENQETT 1041
Cdd:TIGR01612 1315 SEESDInDIKKE----LQKNLLDAQKHNSDINLYLNEIANIYNILK--------LNKIKKIIDEVKEYTKEIEENNKNIK 1382
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1042 RELLKvKDRLIEVERNNATLQAEKQALKTqlkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQS 1121
Cdd:TIGR01612 1383 DELDK-SEKLIKKIKDDINLEECKSKIES---TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKN 1458
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1122 TSLMNQNAQ--LLIQQSALENEKEGVLKELED-------LKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLK---- 1188
Cdd:TIGR01612 1459 IEMADNKSQhiLKIKKDNATNDHDFNINELKEhidkskgCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknk 1538
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1189 --SAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQ---EKMLQQNEKHETVAAEYK-KLRDENDRLAHTHDQLLK 1262
Cdd:TIGR01612 1539 faKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKfriEDDAAKNDKSNKAAIDIQlSLENFENKFLKISDIKKK 1618
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1263 ENEVL---QTDHKNLKTLLNNSKlgQTQLEAEFSKLREEYQLLdikctkisnqcELLSQLKGNMEEENRHlLDQIQTLML 1339
Cdd:TIGR01612 1619 INDCLketESIEKKISSFSIDSQ--DTELKENGDNLNSLQEFL-----------ESLKDQKKNIEDKKKE-LDELDSEIE 1684
|
1210 1220 1230 1240
....*....|....*....|....*....|....*....|...
gi 2024492573 1340 QNRTLLEQNMESKDLFHVEQRQYIDKLN--ELRRQKEKLEEKI 1380
Cdd:TIGR01612 1685 KIEIDVDQHKKNYEIGIIEKIKEIAIANkeEIESIKELIEPTI 1727
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
541-966 |
3.10e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.09 E-value: 3.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 541 KFETLRENLERQIKLLEQENERSNQTIAS-LRQRSQISAEAQMKEIEKENKILHESIKEtssKLNKLEFEIKQVRKEMEH 619
Cdd:COG4717 13 KFRDRTIEFSPGLNVIYGPNEAGKSTLLAfIRAMLLERLEKEADELFKPQGRKPELNLK---ELKELEEELKEAEEKEEE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 620 YKEKAERAEELENELHHLEKENELLQKKIANLSI------TCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLE 693
Cdd:COG4717 90 YAELQEELEELEEELEELEAELEELREELEKLEKllqllpLYQELEALEAELAELPERLEELEERLEELRELEEELEELE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 694 KENSQLDEENLELRRRIESSKCTSIKMAQLQLEN------------KELESEKEQLKK---SLELMKASFKKSERLE--- 755
Cdd:COG4717 170 AELAELQEELEELLEQLSLATEEELQDLAEELEElqqrlaeleeelEEAQEELEELEEeleQLENELEAAALEERLKear 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 756 -------------------------------VSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELV 804
Cdd:COG4717 250 lllliaaallallglggsllsliltiagvlfLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALG 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 805 ISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKdSTLEENNVKinhLEKENKSLFKQIAVYKESCVRLK 884
Cdd:COG4717 330 LPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA-ALLAEAGVE---DEEELRAALEQAEEYQELKEELE 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 885 ELE--MENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSD--DRYKLLESKL 960
Cdd:COG4717 406 ELEeqLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAEllQELEELKAEL 485
|
....*.
gi 2024492573 961 ESTLKK 966
Cdd:COG4717 486 RELAEE 491
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
577-816 |
3.11e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.32 E-value: 3.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 577 SAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMehyKEKAERAEELENELHHLEKENELLQKKIANLSitcE 656
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL---AALERRIAALARRIRALEQELAALEAELAELE---K 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 657 KIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIesSKCTSIKMAQLQLENKELESEKEQ 736
Cdd:COG4942 91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYL--APARREQAEELRADLAELAALRAE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 737 LKkslelmkasfKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKE 816
Cdd:COG4942 169 LE----------AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
483-809 |
6.50e-09 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 61.46 E-value: 6.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 483 DDSVGGNSSRIVKMEKENQRLNKKIEEL-------EKEIVQEKQS-LQDNQNLSKdLMKEKEQLEKKFETLRENLER--- 551
Cdd:PLN02939 106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLvgmiqnaEKNILLLNQArLQALEDLEK-ILTEKEALQGKINILEMRLSEtda 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 552 QIKLLEQEnersnqtiaslrqrsQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRkemehykekaeraeeLE 631
Cdd:PLN02939 185 RIKLAAQE---------------KIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLK---------------EE 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 632 NELhhLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELrrRIE 711
Cdd:PLN02939 235 NML--LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVENLQD--LLD 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 712 SSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDles 791
Cdd:PLN02939 311 RATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKE--- 387
|
330
....*....|....*...
gi 2024492573 792 enqtLQKNLEELVISSKR 809
Cdd:PLN02939 388 ----FQDTLSKLKEESKK 401
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
609-1419 |
8.67e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 60.83 E-value: 8.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 609 EIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQ 688
Cdd:TIGR00606 201 KVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQ 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 689 LESLEKENSQLDEENL-----------ELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFK--KSERLE 755
Cdd:TIGR00606 281 MEKDNSELELKMEKVFqgtdeqlndlyHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLqlQADRHQ 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 756 VSYQGLDTENQRLQKALEnsnkkiqqLEGELQDLESENQTlqKNLEELVIsskrlEQLEKENKLLEQETSQLEKDKKQLE 835
Cdd:TIGR00606 361 EHIRARDSLIQSLATRLE--------LDGFERGPFSERQI--KNFHTLVI-----ERQEDEAKTAAQLCADLQSKERLKQ 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 836 KENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEME-NKELVKRASIDKKTLV-TLREDLVN 913
Cdd:TIGR00606 426 EQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQElRKAERELSKAEKNSLTeTLKKEVKS 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 914 EKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLKKSLEIKEE-----KIAALEARLEESTNL 988
Cdd:TIGR00606 506 LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpNKKQLEDWLHSKSKE 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 989 NQQLRQELKTVKKNYEALKQRQEEermVQNPPPRKGEENQSVNKWEKE---NQETTRELLKVKDRLIEVERNNATLQAEK 1065
Cdd:TIGR00606 586 INQTRDRLAKLNKELASLEQNKNH---INNELESKEEQLSSYEDKLFDvcgSQDEESDLERLKEEIEKSSKQRAMLAGAT 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1066 QALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGV 1145
Cdd:TIGR00606 663 AVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLK 742
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1146 LKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLK------SAHKNLEVEHKDLEDRYSQLLkQKVQLEELE 1219
Cdd:TIGR00606 743 EKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltdvTIMERFQMELKDVERKIAQQA-AKLQGSDLD 821
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1220 KVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKlgqtQLEAEFSKLREEY 1299
Cdd:TIGR00606 822 RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ----QFEEQLVELSTEV 897
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1300 QLLDIKCTKISNQCELLSQLKGNMEEENRHLLDQIQT--------LMLQNRTLLEQNMESKDLFHVEQ----RQYIDK-- 1365
Cdd:TIGR00606 898 QSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETsnkkaqdkVNDIKEKVKNIHGYMKDIENKIQdgkdDYLKQKet 977
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 1366 --------LNELRRQKEKLEEKIMDQYKFYEPSPPRRRGNWITLKMRKLMKSKKDVNRERQK 1419
Cdd:TIGR00606 978 elntvnaqLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQ 1039
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
883-1347 |
9.01e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.55 E-value: 9.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 883 LKELEMENKELVK----RASIDKKTLVTLREDLVNEKLKT---QQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKL 955
Cdd:COG4717 48 LERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 956 LESKLE-STLKKSLEIKEEKIAALEARLEEStnlnQQLRQELKTVKKNYEALKQRQEEERmvqnppprkgeeNQSVNKWE 1034
Cdd:COG4717 128 LPLYQElEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELL------------EQLSLATE 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1035 KENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQnnnlqaqiLALQRQTVSLQEQNTTLQTQNAKLQVEN 1114
Cdd:COG4717 192 EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENE--------LEAAALEERLKEARLLLLIAAALLALLG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1115 STLNSQSTSLMNQNAQLLIQQSALenekeGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNL 1194
Cdd:COG4717 264 LGGSLLSLILTIAGVLFLVLGLLA-----LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEE 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1195 EVEHKDLEDRYSQLLKQKVQLEE--LEKVLKTEQEKMLQQN-----EKHETVAAEYKKLRDENDRLAHTHDQLLKENEVL 1267
Cdd:COG4717 339 LLELLDRIEELQELLREAEELEEelQLEELEQEIAALLAEAgvedeEELRAALEQAEEYQELKEELEELEEQLEELLGEL 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1268 QTDHKnlktllnnsKLGQTQLEAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENR--HLLDQIQTLMLQNRTLL 1345
Cdd:COG4717 419 EELLE---------ALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELA 489
|
..
gi 2024492573 1346 EQ 1347
Cdd:COG4717 490 EE 491
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
825-1380 |
9.35e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 60.52 E-value: 9.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 825 SQLEKDKKQLEKENKRLRQQAEIKDSTLEENnvkINHLEKENKSLFKQIAVYKEscvRLKELEMENKELVKRASIDKKTL 904
Cdd:pfam05557 12 SQLQNEKKQMELEHKRARIELEKKASALKRQ---LDRESDRNQELQKRIRLLEK---REAEAEEALREQAELNRLKKKYL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 905 VTLREdLVNEKLKTQQ--------MNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLE--STLKKSLEIKEEK 974
Cdd:pfam05557 86 EALNK-KLNEKESQLAdareviscLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASeaEQLRQNLEKQQSS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 975 IAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQnpppRKGEENQSVNKWEKENQETTRELLKVKDRLIEV 1054
Cdd:pfam05557 165 LAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELE----RLREHNKHLNENIENKLLLKEEVEDLKRKLERE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1055 ERNN---ATLQAEKQALKTQLKQLEtqnNNLQAQILALqRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTslmnqnaQL 1131
Cdd:pfam05557 241 EKYReeaATLELEKEKLEQELQSWV---KLAQDTGLNL-RSPEDLSRRIEQLQQREIVLKEENSSLTSSAR-------QL 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1132 LIQQSALENEKEGVLKELEDLKslydSLLKDHEKLEHLHERQAS----EYESLIAKHGSLKSAHKNLEVEHKDLEDRYS- 1206
Cdd:pfam05557 310 EKARRELEQELAQYLKKIEDLN----KKLKRHKALVRRLQRRVLlltkERDGYRAILESYDKELTMSNYSPQLLERIEEa 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1207 --QLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDrlahTHDQLLKENEVLQTDHKNLKTLLNNSKLG 1284
Cdd:pfam05557 386 edMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQES----LADPSYSKEEVDSLRRKLETLELERQRLR 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1285 QTQLEAEFSKLREEYQ-LLDIKCTKI----SNQCELLSQLKGNM----EEENRHLLDQIQTLMLQNRTLLEQNMESKDLF 1355
Cdd:pfam05557 462 EQKNELEMELERRCLQgDYDPKKTKVlhlsMNPAAEAYQQRKNQleklQAEIERLKRLLKKLEDDLEQVLRLPETTSTMN 541
|
570 580
....*....|....*....|....*
gi 2024492573 1356 HVEqrqyidkLNELRRQKEKLEEKI 1380
Cdd:pfam05557 542 FKE-------VLDLRKELESAELKN 559
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
521-869 |
1.11e-08 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 59.91 E-value: 1.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 521 LQDNQNLSKDLMKEKEQLEKKFE-------TLRENLERQIKLLEQENERSNQTIASLRQRSQisaeaQMKEIEKENKILH 593
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREkekerykRDREQWERQRRELESRVAELKEELRQSREKHE-----ELEEKYKELSASS 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 594 ESIKETSSKLNKLEFEIKQVRKEMEH-YKEKAERAEELENELHHLEKEnellQKKIANLsitcEKIEALEKENSDLdien 672
Cdd:pfam07888 111 EELSEEKDALLAQRAAHEARIRELEEdIKTLTQRVLERETELERMKER----AKKAGAQ----RKEEEAERKQLQA---- 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 673 rKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESskcTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSE 752
Cdd:pfam07888 179 -KLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITT---LTQKLTTAHRKEAENEALLEELRSLQERLNASERKVE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDL-----------ESENQTLQKNLE-ELVISSKRLEQLEKENKLL 820
Cdd:pfam07888 255 GLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADAslalregrarwAQERETLQQSAEaDKDRIEKLSAELQRLEERL 334
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 2024492573 821 EQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSL 869
Cdd:pfam07888 335 QEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQL 383
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
260-1103 |
1.16e-08 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 60.57 E-value: 1.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 260 RRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDELdilrEKAIRvdKLESEVGRYKERLHDME 339
Cdd:pfam01576 211 RKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNA----LKKIR--ELEAQISELQEDLESER 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 340 FYKARVEELMEDNQVMLET-KRMFEDQVKTLQCRSDKLHVVEKENLQLK------AKLHEMEME--RDMDRKKIEELMEE 410
Cdd:pfam01576 285 AARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQemRQKHTQALEELTEQ 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 411 -------NMALEMAQKQSMDESLHLGWELEQINRFTDHSEVSHKSLGLEVTELtSSRLLKLEKENQSLLKTVEELRSTMD 483
Cdd:pfam01576 365 leqakrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQRAELAEKLSKLQSELE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 484 DSvggnSSRIVKMEKENQRLNKKIEELEKEivqekqsLQDNQNLSKDLMKEKEQLEKKfetLRENLERQIKLLEQENERS 563
Cdd:pfam01576 444 SV----SSLLNEAEGKNIKLSKDVSSLESQ-------LQDTQELLQEETRQKLNLSTR---LRQLEDERNSLQEQLEEEE 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 564 NQTIASLRQRSqiSAEAQMKEIEKEnkilhesIKETSSKLNKLEFEIKQVRKEMEhykEKAERAEELENELHHLEKENEL 643
Cdd:pfam01576 510 EAKRNVERQLS--TLQAQLSDMKKK-------LEEDAGTLEALEEGKKRLQRELE---ALTQQLEEKAAAYDKLEKTKNR 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 644 LQKKIANLSITCEKIEALEkenSDLDIENRKLKKTLDSLKNLSFQL---------ESLEKENSQLD-----EENLELRRR 709
Cdd:pfam01576 578 LQQELDDLLVDLDHQRQLV---SNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRALSlaralEEALEAKEE 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 710 IESSKctsiKMAQLQLEN------------KELESEKEQLKKSLELMKASFKKSE-----------RLEVSYQGLDTENQ 766
Cdd:pfam01576 655 LERTN----KQLRAEMEDlvsskddvgknvHELERSKRALEQQVEEMKTQLEELEdelqatedaklRLEVNMQALKAQFE 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 767 R-LQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLE--------QLEKENKLLEQETSQLEKDK---KQL 834
Cdd:pfam01576 731 RdLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKKLQaqmKDL 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 835 EKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVY----KESCVRLKEL--EMENKELVKRASIDKK-----T 903
Cdd:pfam01576 811 QRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASerarRQAQQERDELadEIASGASGKSALQDEKrrleaR 890
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 904 LVTLREDLVNEKLKTQQMNNDLEKLSHELEKIG--LNKERLLC----------DEQSSDDRYKL--LESKLESTLKKSLE 969
Cdd:pfam01576 891 IAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTteLAAERSTSqksesarqqlERQNKELKAKLqeMEGTVKSKFKSSIA 970
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 970 IKEEKIAALEARLEESTNLNQQLRQEL-KTVKKNYEALKQRQEEERMVQnppprkgeenqsvnkwekenqettrellKVK 1048
Cdd:pfam01576 971 ALEAKIAQLEEQLEQESRERQAANKLVrRTEKKLKEVLLQVEDERRHAD----------------------------QYK 1022
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 1049 DrliEVERNNATLQAekqaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTL 1103
Cdd:pfam01576 1023 D---QAEKGNSRMKQ----LKRQLEEAEEEASRANAARRKLQRELDDATESNESM 1070
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
458-682 |
1.19e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.39 E-value: 1.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 458 SSRLLKLEKENQSLLKTVEELRSTMDDsvggNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQ 537
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAA----LKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 538 LEKKFETLRENLERQIKLLeQENERSNQTIASLRQRS---QISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVR 614
Cdd:COG4942 95 LRAELEAQKEELAELLRAL-YRLGRQPPLALLLSPEDfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 615 kemehyKEKAERAEELENELHHLEKENELLQKKIANLSitcEKIEALEKENSDLDIENRKLKKTLDSL 682
Cdd:COG4942 174 ------AELEALLAELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARL 232
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
719-934 |
1.61e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.01 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 719 KMAQLQLENKELESEKEQLKKSLELMKasfKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQK 798
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALK---KEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 799 NLE-------ELVISSKRLEQLEKENKLLEQET-SQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLF 870
Cdd:COG4942 98 ELEaqkeelaELLRALYRLGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024492573 871 KQIAVYKESCVRLKELEMENKELVKRAsidKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEK 934
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARL---EKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
621-1090 |
1.86e-08 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 59.32 E-value: 1.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 621 KEKAERAEELENELHHLEKENELLQkkianlsitcekiealeKENSDLDIENRKLKKTLDslknlsfQLESLEKENSQLD 700
Cdd:pfam05622 3 SEAQEEKDELAQRCHELDQQVSLLQ-----------------EEKNSLQQENKKLQERLD-------QLESGDDSGTPGG 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 701 EENLELRRRIEsskctsikmaQLQLENKELESEKEQLKkslelmkasfKKSERLEVSYQGLDTENQRLQKALEnsnkKIQ 780
Cdd:pfam05622 59 KKYLLLQKQLE----------QLQEENFRLETARDDYR----------IKCEELEKEVLELQHRNEELTSLAE----EAQ 114
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 781 QLEGELQDLESENQTLQKnLEELVISSKR----LEQLEKENKLLEQETSQLEKDKKQLEKENKR---LRQQAEIKDSTLE 853
Cdd:pfam05622 115 ALKDEMDILRESSDKVKK-LEATVETYKKkledLGDLRRQVKLLEERNAEYMQRTLQLEEELKKanaLRGQLETYKRQVQ 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 854 ENNVKinhLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASidkktlvTLREdlVNEKLK-TQQMNNDLEKLSHEL 932
Cdd:pfam05622 194 ELHGK---LSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERD-------TLRE--TNEELRcAQLQQAELSQADALL 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 933 EKIGLNKERLLCDEQSSDDRYKLLESKLEStlkKSLEIK-----EEKIAALEARLEESTNLNQQLRQELKTVKKNYEALK 1007
Cdd:pfam05622 262 SPSSDPGDNLAAEIMPAEIREKLIRLQHEN---KMLRLGqegsyRERLTELQQLLEDANRRKNELETQNRLANQRILELQ 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1008 QRQEEERMVQNPPPRKGEENQSVNKWEKENQETTREllkvkdrlievernnatLQAEKQALKTQLKQLE-TQNNNLQAQI 1086
Cdd:pfam05622 339 QQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLHE-----------------AQSELQKKKEQIEELEpKQDSNLAQKI 401
|
....
gi 2024492573 1087 LALQ 1090
Cdd:pfam05622 402 DELQ 405
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
985-1217 |
1.94e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 985 STNLNQQLRQELKTVKKNYEALKQRQEEERMvqnpppRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAE 1064
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKK------EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1065 KQALKtqlKQLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST--LNSQSTSLMNQNAQLLIQQSALENEK 1142
Cdd:COG4942 92 IAELR---AELEAQKEELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALR 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 1143 EGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKVQLEE 1217
Cdd:COG4942 167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
251-803 |
2.01e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 59.54 E-value: 2.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 251 ELADAKAKIRRLRQEIE----EKNEQFLD-YKQELERVETELRRLQQENKNLLSDARSARVYRDEL--DILREKAIRVDK 323
Cdd:COG4913 263 RYAAARERLAELEYLRAalrlWFAQRRLElLEAELEELRAELARLEAELERLEARLDALREELDELeaQIRGNGGDRLEQ 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 324 LESEVGRYKERLHDMEFYKARVEELMEDNQVML-ETKRMFEDQVKTLQCRSDKLHVVEKEnlqLKAKLHEMEMERDMDRK 402
Cdd:COG4913 343 LEREIERLERELEERERRRARLEALLAALGLPLpASAEEFAALRAEAAALLEALEEELEA---LEEALAEAEAALRDLRR 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 403 KIEELMEENMALEmAQKQSMDESLHlgwEL-EQINRftdhsevshkSLGLEVTELtssR----LLKLEKENQSLLKTVEE 477
Cdd:COG4913 420 ELRELEAEIASLE-RRKSNIPARLL---ALrDALAE----------ALGLDEAEL---PfvgeLIEVRPEEERWRGAIER 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 478 LrstmddsVGGNSSRIVKMEKENQRLNKKIEELEK------EIVQEKQSLQDNQNLSKDLMKEKeqLEKKFETLRENLER 551
Cdd:COG4913 483 V-------LGGFALTLLVPPEHYAAALRWVNRLHLrgrlvyERVRTGLPDPERPRLDPDSLAGK--LDFKPHPFRAWLEA 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 552 QIklleqeNERSN----QTIASLRQ-RSQISAEAQMK------EIEKENKILHESI--KETSSKLNKLEFEIKQVRKEME 618
Cdd:COG4913 554 EL------GRRFDyvcvDSPEELRRhPRAITRAGQVKgngtrhEKDDRRRIRSRYVlgFDNRAKLAALEAELAELEEELA 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 619 hykEKAERAEELENELHHLEKENELLQKkIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQ 698
Cdd:COG4913 628 ---EAEERLEALEAELDALQERREALQR-LAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEE 703
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 699 LDEENLELRRRIesskctsikmAQLQLENKELESEKEQLKKSLELMkasfkksERLEVSYQGLDTENQRLQKALENSNKK 778
Cdd:COG4913 704 LEEELDELKGEI----------GRLEKELEQAEEELDELQDRLEAA-------EDLARLELRALLEERFAAALGDAVERE 766
|
570 580
....*....|....*....|....*.
gi 2024492573 779 I-QQLEGELQDLESENQTLQKNLEEL 803
Cdd:COG4913 767 LrENLEERIDALRARLNRAEEELERA 792
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
743-1353 |
4.35e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.58 E-value: 4.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 743 LMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVIS----SKRLEQLEKENK 818
Cdd:pfam05483 65 LKDSDFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFEnekvSLKLEEEIQENK 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 819 LLEQETS---------------QLEKDKK-QLEKENKR-------------------LRQQAEIK----DSTLEENNVKI 859
Cdd:pfam05483 145 DLIKENNatrhlcnllketcarSAEKTKKyEYEREETRqvymdlnnniekmilafeeLRVQAENArlemHFKLKEDHEKI 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 860 NHLEKEnkslFKQIAVYKESCVRL-------KELEMENKELVKRASIDKKTLVTLREDLVNEKLKtqQMNNDLEKLSHEL 932
Cdd:pfam05483 225 QHLEEE----YKKEINDKEKQVSLlliqiteKENKMKDLTFLLEESRDKANQLEEKTKLQDENLK--ELIEKKDHLTKEL 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 933 EKIGLNKERLLCDEqssddryKLLESKLESTLKKSLEIKEEKIAALEaRLEESTNLNQQLRQELKTVKKNYEALkQRQEE 1012
Cdd:pfam05483 299 EDIKMSLQRSMSTQ-------KALEEDLQIATKTICQLTEEKEAQME-ELNKAKAAHSFVVTEFEATTCSLEEL-LRTEQ 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1013 ERMVQNPP---------PRKGEENQSVNKWEKENQETTRELLKV---KDRLI----EVERNNATLQAEKQALKTQLKQLE 1076
Cdd:pfam05483 370 QRLEKNEDqlkiitmelQKKSSELEEMTKFKNNKEVELEELKKIlaeDEKLLdekkQFEKIAEELKGKEQELIFLLQARE 449
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1077 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLY 1156
Cdd:pfam05483 450 KEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQE 529
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1157 DSLLKDHEKLEHLHERQASEYES----LIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQE-KMLQ 1231
Cdd:pfam05483 530 ERMLKQIENLEEKEMNLRDELESvreeFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEnKNKN 609
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1232 QNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNsklgqTQLEAEFSKLREEYQLLDIKCTKISn 1311
Cdd:pfam05483 610 IEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDN-----YQKEIEDKKISEEKLLEEVEKAKAI- 683
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 2024492573 1312 qCELLSQLKGNMEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1353
Cdd:pfam05483 684 -ADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERD 724
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
401-817 |
6.28e-08 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 57.54 E-value: 6.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 401 RKKIEELMEENMALEmaqkqsmdeSLHLGWELEQIN--RFTDHSEVSHKSLGLEVTELTSSRLLKLEKenqsLLKTVEEL 478
Cdd:PRK04778 28 YKRIDELEERKQELE---------NLPVNDELEKVKklNLTGQSEEKFEEWRQKWDEIVTNSLPDIEE----QLFEAEEL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 479 rstmddsvgGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLR------------ 546
Cdd:PRK04778 95 ---------NDKFRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRksllanrfsfgp 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 547 ---------ENLERQIKLLEQENERSNQTIAS---LRQRSQISA-EAQMKEIEkenKILHESIKETSSKLNKLE------ 607
Cdd:PRK04778 166 aldelekqlENLEEEFSQFVELTESGDYVEAReilDQLEEELAAlEQIMEEIP---ELLKELQTELPDQLQELKagyrel 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 608 ------FEIKQVRKEMEHYKEKAERAEELENELH--HLEKENELLQKKIANLSITCEK-IEA---LEKENSDLDienRKL 675
Cdd:PRK04778 243 veegyhLDHLDIEKEIQDLKEQIDENLALLEELDldEAEEKNEEIQERIDQLYDILEReVKArkyVEKNSDTLP---DFL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 676 KKTLDSLKNLSFQLESLeKENSQLDEENLELRRRIEsskctsikmaqlqlenKELESEKEQLKKSLELMKASfkkserlE 755
Cdd:PRK04778 320 EHAKEQNKELKEEIDRV-KQSYTLNESELESVRQLE----------------KQLESLEKQYDEITERIAEQ-------E 375
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 756 VSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEEL---VISSKRLeqLEKEN 817
Cdd:PRK04778 376 IAYSELQEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYrnkLHEIKRY--LEKSN 438
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
454-830 |
6.55e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 58.06 E-value: 6.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 454 TELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQ--SLQDNQNLSKDL 531
Cdd:pfam02463 666 ASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQdkINEELKLLKQKI 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 532 MKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIK 611
Cdd:pfam02463 746 DEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIE 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 612 QvrkemehykekAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLES 691
Cdd:pfam02463 826 Q-----------EEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK 894
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 692 LEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLkkslelmkasfKKSERLEVSYQGLDTENQRLQKA 771
Cdd:pfam02463 895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL-----------LLEEADEKEKEENNKEEEEERNK 963
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 772 LENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKD 830
Cdd:pfam02463 964 RLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
18-163 |
7.74e-08 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 53.70 E-value: 7.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 18 LVTWVRTFgpladENGTSLEEYMTLVDGVFLNEVMLQINP----KSTNRNVNKRVNNDESLRIQNLCILVKKIKYFYQEC 93
Cdd:cd22225 5 LIIWLQTF-----NTAAPCQTVQDLTSGVAMAQVLHQIDSswfdESWLSRIKEDVGDNWRIKMSNLKKILQGIVDYYHEF 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 94 L-QQLIVMALPNVLIIGRNplSEPgtNEINKILLLLLGCAVQCQKKEEFIERIQHLDFDTRAAVAAHIQEV 163
Cdd:cd22225 80 LdQQISEFLLPDLNRIAEH--SDP--VELGRLLQLILGCAVNCEKKQEHIQNIMTLEESVQHVVMTAIQEL 146
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
806-1078 |
9.42e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.70 E-value: 9.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 806 SSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQaeikdstLEENNVKINHLEKENKSLFKQIAVYKEscvRLKE 885
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ-------LAALERRIAALARRIRALEQELAALEA---ELAE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 886 LEMENKELvkRASIDKktlvtlREDLVNEKLKTQQMNNDLEKLshelekiglnkeRLLCDEQSSDDRYKLLEsklesTLK 965
Cdd:COG4942 88 LEKEIAEL--RAELEA------QKEELAELLRALYRLGRQPPL------------ALLLSPEDFLDAVRRLQ-----YLK 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 966 KSLEIKEEKIAALEARLEEStnlnQQLRQELKTVKKNYEALKQRQEEERmvqnppprkgeenqsvNKWEKENQETTRELL 1045
Cdd:COG4942 143 YLAPARREQAEELRADLAEL----AALRAELEAERAELEALLAELEEER----------------AALEALKAERQKLLA 202
|
250 260 270
....*....|....*....|....*....|...
gi 2024492573 1046 KVKDRLIEVERNNATLQAEKQALKTQLKQLETQ 1078
Cdd:COG4942 203 RLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1021-1217 |
9.68e-08 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 56.38 E-value: 9.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1021 PRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsLQEQN 1100
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREE---LGERA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1101 TTLQTQNAKLQVENSTLNSQSTS-----------LMNQNAQLLIQQSA----LENEKEGVLKELEDLKSLYDSLLKDHEK 1165
Cdd:COG3883 93 RALYRSGGSVSYLDVLLGSESFSdfldrlsalskIADADADLLEELKAdkaeLEAKKAELEAKLAELEALKAELEAAKAE 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 1166 LEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKVQLEE 1217
Cdd:COG3883 173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
254-750 |
1.03e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 57.54 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 254 DAKAKIRRLRQEIEEKNEQFL-DYKQELERVETELRRLQQENKNLLSDARSArvYRDELDI-LREKAIRVDKLESEVGRY 331
Cdd:pfam12128 372 DVTAKYNRRRSKIKEQNNRDIaGIKDKLAKIREARDRQLAVAEDDLQALESE--LREQLEAgKLEFNEEEYRLKSRLGEL 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 332 KERLHDMEfykARVEELMEDNQVMLETKRMFEDQVKTLQCRS---DKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELM 408
Cdd:pfam12128 450 KLRLNQAT---ATPELLLQLENFDERIERAREEQEAANAEVErlqSELRQARKRRDQASEALRQASRRLEERQSALDELE 526
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 409 EENMA-----LEMAQKQSMDESLHLGWEL--EQINRFTDHSEVSHKSLGLEVTeLTSSRLLKLEKENQSLLKTVEELRST 481
Cdd:pfam12128 527 LQLFPqagtlLHFLRKEAPDWEQSIGKVIspELLHRTDLDPEVWDGSVGGELN-LYGVKLDLKRIDVPEWAASEEELRER 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 482 MD---DSVGGNSSRIVKMEKENQRLNKKIEELEKE-----------------IVQEKQSLQDNQNLS------------K 529
Cdd:pfam12128 606 LDkaeEALQSAREKQAAAEEQLVQANGELEKASREetfartalknarldlrrLFDEKQSEKDKKNKAlaerkdsanerlN 685
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 530 DLMKEKEQLEKKF--------ETLREN-LERQIKLLEQENERSNQtIASLRQ---RSQISAEAQMKEIEKENKILHESIK 597
Cdd:pfam12128 686 SLEAQLKQLDKKHqawleeqkEQKREArTEKQAYWQVVEGALDAQ-LALLKAaiaARRSGAKAELKALETWYKRDLASLG 764
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 598 ETSSKLNKLEFEIkqvrKEMEHYKEKAERAEELENELHHLEKENELLQKKiaNLSITCEKIealEKENSDLDIE-NRKLK 676
Cdd:pfam12128 765 VDPDVIAKLKREI----RTLERKIERIAVRRQEVLRYFDWYQETWLQRRP--RLATQLSNI---ERAISELQQQlARLIA 835
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 677 KTLDSLKNLSFQLESLEKENSQLDEENLELRRRIesSKCTSIKM----AQLQLENKELESEKEQLKKSLELMKASFKK 750
Cdd:pfam12128 836 DTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM--SKLATLKEdansEQAQGSIGERLAQLEDLKLKRDYLSESVKK 911
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
656-1382 |
1.16e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 57.36 E-value: 1.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 656 EKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKE 735
Cdd:TIGR00606 200 QKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKK 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 736 QLKKSLELMkasfkkSERLEVSYQGLDTenqrlqkalensnkkiqqlegELQDLESENQ-TLQKNLEELVISSKRLEQLE 814
Cdd:TIGR00606 280 QMEKDNSEL------ELKMEKVFQGTDE---------------------QLNDLYHNHQrTVREKERELVDCQRELEKLN 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 815 KENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKInHLEKENKSLFKQIAVYKESCVRLKELEMENKELV 894
Cdd:TIGR00606 333 KERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL-ELDGFERGPFSERQIKNFHTLVIERQEDEAKTAA 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 895 KRASIDKKTLVTLREDL----VNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLKKSLEI 970
Cdd:TIGR00606 412 QLCADLQSKERLKQEQAdeirDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAE 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 971 KEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSV--NKWEKENQET-------- 1040
Cdd:TIGR00606 492 KNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIrkIKSRHSDELTsllgyfpn 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1041 -----------TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL------ALQRQTVSLQEQNTTL 1103
Cdd:TIGR00606 572 kkqledwlhskSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFdvcgsqDEESDLERLKEEIEKS 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1104 QTQNAKLQVENSTLNSQSTSLMNQN--------------AQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHL 1169
Cdd:TIGR00606 652 SKQRAMLAGATAVYSQFITQLTDENqsccpvcqrvfqteAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGL 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1170 HERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQ---LLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKL 1246
Cdd:TIGR00606 732 APGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEqetLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQ 811
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1247 RDENDR--LAHTHDQLLKENEvlQTDHKnLKTLLNNSKLGQTQLEAEfsklREEYQLLDIKCTKISNQCELLS---QLKG 1321
Cdd:TIGR00606 812 AAKLQGsdLDRTVQQVNQEKQ--EKQHE-LDTVVSKIELNRKLIQDQ----QEQIQHLKSKTNELKSEKLQIGtnlQRRQ 884
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 1322 NMEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMD 1382
Cdd:TIGR00606 885 QFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVND 945
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
573-1010 |
1.21e-07 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 57.23 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 573 RSQISAEAQMKEIEKENKILHESIKETSSKLNKlefeIKQVRKEMEHYKEKAERA----EELENELHHLEKEN-ELLQKK 647
Cdd:PRK11281 42 QAQLDALNKQKLLEAEDKLVQQDLEQTLALLDK----IDRQKEETEQLKQQLAQApaklRQAQAELEALKDDNdEETRET 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 648 IANLSitcekIEALEKensdldienrKLKKTLDSLKNLSFQLESLekeNSQLdeenLELRRRIESskctsikmAQLQL-E 726
Cdd:PRK11281 118 LSTLS-----LRQLES----------RLAQTLDQLQNAQNDLAEY---NSQL----VSLQTQPER--------AQAALyA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 727 NKELESEKEQLKKSLELMKASFKKSER--LEVSYQGLDTENQRLQKALENsNKKIQQLEGELQDLESENQT-LQKNLEEL 803
Cdd:PRK11281 168 NSQRLQQIRNLLKGGKVGGKALRPSQRvlLQAEQALLNAQNDLQRKSLEG-NTQLQDLLQKQRDYLTARIQrLEHQLQLL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 804 --VISSKRLEQLEKENKLLE--QETSQLEKD---KKQLEKeNKRLRQ---QAEIKDSTLEENNVKI-NHLEKENKS---L 869
Cdd:PRK11281 247 qeAINSKRLTLSEKTVQEAQsqDEAARIQANplvAQELEI-NLQLSQrllKATEKLNTLTQQNLRVkNWLDRLTQSernI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 870 FKQIAVYKESCVRLKELemeNKElvkrasidKKTLVTLREDlvneklktQQMNNDLEKLshELEKIGLNKERllcDEQSS 949
Cdd:PRK11281 326 KEQISVLKGSLLLSRIL---YQQ--------QQALPSADLI--------EGLADRIADL--RLEQFEINQQR---DALFQ 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024492573 950 DDRY--KLLE---SKLESTLKKSL--------EIKEEKIAALEARLEESTNLnQQLRQELKTVKKNYEALKQRQ 1010
Cdd:PRK11281 382 PDAYidKLEAghkSEVTDEVRDALlqllderrELLDQLNKQLNNQLNLAINL-QLNQQQLLSVSDSLQSTLTQQ 454
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
725-1285 |
1.49e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 56.83 E-value: 1.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 725 LENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELV 804
Cdd:PRK01156 159 LEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLK 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 805 ISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAE----IKDSTLEENNVKIN----------HLEKENKSLF 870
Cdd:PRK01156 239 SALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEErhmkIINDPVYKNRNYINdyfkykndieNKKQILSNID 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 871 KQIAVYKESCVRLKELEMENKELVKRASiDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSD 950
Cdd:PRK01156 319 AEINKYHAIIKKLSVLQKDYNDYIKKKS-RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEIL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 951 DRYKLLESKLESTL---KKSLEIKEEKIAALEARLEestnlnqQLRQELKTVKKNYEALKQR------------QEEERM 1015
Cdd:PRK01156 398 KIQEIDPDAIKKELneiNVKLQDISSKVSSLNQRIR-------ALRENLDELSRNMEMLNGQsvcpvcgttlgeEKSNHI 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1016 VQNPPPRKGEENQSVNKWEKENQ---ETTRELLKVKDRLIEVERNnatlqaEKQALKTQLKQLETQNNNLQAQILALQRQ 1092
Cdd:PRK01156 471 INHYNEKKSRLEEKIREIEIEVKdidEKIVDLKKRKEYLESEEIN------KSINEYNKIESARADLEDIKIKINELKDK 544
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1093 TVSLQEqnttLQTQNAKLQVENstLNSQSTSLMNQNAQL-LIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHE 1171
Cdd:PRK01156 545 HDKYEE----IKNRYKSLKLED--LDSKRTSWLNALAVIsLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYID 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1172 rqaseyesliakhgslkSAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDEND 1251
Cdd:PRK01156 619 -----------------KSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIED 681
|
570 580 590
....*....|....*....|....*....|....*
gi 2024492573 1252 RLAHTHDQLLKENEVLQTDHKNLKTLL-NNSKLGQ 1285
Cdd:PRK01156 682 NLKKSRKALDDAKANRARLESTIEILRtRINELSD 716
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
728-1280 |
1.69e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.85 E-value: 1.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 728 KELESEKEQLKkSLELMKASFKKSERLEVSYQGLD------------TENQRLQKALENSNKKIQQLEGELQDLESENQT 795
Cdd:COG4913 242 EALEDAREQIE-LLEPIRELAERYAAARERLAELEylraalrlwfaqRRLELLEAELEELRAELARLEAELERLEARLDA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 796 LQKNLEELV-----ISSKRLEQLEKENKlleqetsQLEKDKKQLEKENKRLRQQAEIKDSTLEENnvkinhlEKENKSLF 870
Cdd:COG4913 321 LREELDELEaqirgNGGDRLEQLEREIE-------RLERELEERERRRARLEALLAALGLPLPAS-------AEEFAALR 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 871 KQIAVYKEscvRLKELEMENKELVKRASIDKKTLVTLREDLVNEK--LKTQQMNND--LEKLSHEL-EKIGLNKERL--L 943
Cdd:COG4913 387 AEAAALLE---ALEEELEALEEALAEAEAALRDLRRELRELEAEIasLERRKSNIParLLALRDALaEALGLDEAELpfV 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 944 CDeqssddrykLLESKLES------------TLKKSLEIKEEKIAALeARLEESTNLNQQLRqelktvkknYEALKQRQE 1011
Cdd:COG4913 464 GE---------LIEVRPEEerwrgaiervlgGFALTLLVPPEHYAAA-LRWVNRLHLRGRLV---------YERVRTGLP 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1012 eermvqNPPPRKGEENQSVNKWE-KEN--QETTRELLKVKDRLIEVErNNATLQAEKQALkT---QLKQLET-------- 1077
Cdd:COG4913 525 ------DPERPRLDPDSLAGKLDfKPHpfRAWLEAELGRRFDYVCVD-SPEELRRHPRAI-TragQVKGNGTrhekddrr 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1078 ---------QNNnlQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaQLLIQQSALENEKEGVLKE 1148
Cdd:COG4913 597 rirsryvlgFDN--RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-----QRLAEYSWDEIDVASAERE 669
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1149 LEDLKSLYDSLLKDHEKLEHLhERQASEyesliakhgsLKSAHKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQEK 1228
Cdd:COG4913 670 IAELEAELERLDASSDDLAAL-EEQLEE----------LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA 738
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 2024492573 1229 M--LQQNEKHETVAAEYKKLRDENdRLAHTHDQLLKENEVLQTDHKNLKTLLNN 1280
Cdd:COG4913 739 AedLARLELRALLEERFAAALGDA-VERELRENLEERIDALRARLNRAEEELER 791
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
332-650 |
1.91e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 56.29 E-value: 1.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 332 KERLHDMEFYKARVEElmEDNQVMLETKRMFEDQVKTLQCRSDKLHVVEKENLQLKaklheMEMERDMDRKKIEELMEEN 411
Cdd:pfam17380 290 QEKFEKMEQERLRQEK--EEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMA-----MERERELERIRQEERKREL 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 412 malEMAQKQSMDESLHLGWELE--QINRFTDHSEVSHkslglevtELTSSRLLK-LEKENQSLLK-TVEELRSTMDDSVG 487
Cdd:pfam17380 363 ---ERIRQEEIAMEISRMRELErlQMERQQKNERVRQ--------ELEAARKVKiLEEERQRKIQqQKVEMEQIRAEQEE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 488 GNSSRIVKMEKENQRLNKKI--EELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKfetLRENLERqiKLLEQENERsnq 565
Cdd:pfam17380 432 ARQREVRRLEEERAREMERVrlEEQERQQQVERLRQQEEERKRKKLELEKEKRDRK---RAEEQRR--KILEKELEE--- 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 566 tiaslRQRSQISAEAQMKEIEKENKILHESIKETSSKlnKLEFEIKQVRKEMEHYK---EKAERAEELENELHHLEKENE 642
Cdd:pfam17380 504 -----RKQAMIEEERKRKLLEKEMEERQKAIYEEERR--REAEEERRKQQEMEERRriqEQMRKATEERSRLEAMERERE 576
|
....*...
gi 2024492573 643 LLQKKIAN 650
Cdd:pfam17380 577 MMRQIVES 584
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
609-1165 |
2.47e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.08 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 609 EIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLsitcEKIEALEKENSDLDIENRKLKktLDSLKNlsfQ 688
Cdd:COG4913 226 AADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAAR----ERLAELEYLRAALRLWFAQRR--LELLEA---E 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 689 LESLEKENSQLDEENLELRRRIEsskctsikmaqlqlenkELESEKEQLKKslELMKASFKKSERLEvsyqgldTENQRL 768
Cdd:COG4913 297 LEELRAELARLEAELERLEARLD-----------------ALREELDELEA--QIRGNGGDRLEQLE-------REIERL 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 769 QKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSK-RLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQqaEI 847
Cdd:COG4913 351 ERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAaLLEALEEELEALEEALAEAEAALRDLRRELRELEA--EI 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 848 KDstLEENNVKINHLEKENKSLFKQIAVYKESCVR-LKEL-EMENKELVKRASIDK-----KT--LVT------------ 906
Cdd:COG4913 429 AS--LERRKSNIPARLLALRDALAEALGLDEAELPfVGELiEVRPEEERWRGAIERvlggfALtlLVPpehyaaalrwvn 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 907 ---LREDLVNEKLKTQQMNNDLEK-----LSHELE------------KIGLNKERLLCD--EQSSDDRYKLLESKLESTL 964
Cdd:COG4913 507 rlhLRGRLVYERVRTGLPDPERPRldpdsLAGKLDfkphpfrawleaELGRRFDYVCVDspEELRRHPRAITRAGQVKGN 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 965 KKSLEIK---------------EEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRkgeenqs 1029
Cdd:COG4913 587 GTRHEKDdrrrirsryvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWD------- 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1030 vnkwEKENQETTRELLKVKDRLIEVERNNATLqaekQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAK 1109
Cdd:COG4913 660 ----EIDVASAEREIAELEAELERLDASSDDL----AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDE 731
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 1110 LQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEK 1165
Cdd:COG4913 732 LQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
770-1143 |
2.73e-07 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 56.07 E-value: 2.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 770 KALENSNKKIQQLEgelqDLESENQTLQKNLEElvisskRLEQLEKenklleqetsqlekdKKQLEKENKRLRQQAEIKD 849
Cdd:PRK11281 39 ADVQAQLDALNKQK----LLEAEDKLVQQDLEQ------TLALLDK---------------IDRQKEETEQLKQQLAQAP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 850 STLEENNVKINHLEKENKSLFKQIaVYKEScvrLKELEMENKELVKRASIDKKTLVTLREDLVNEK-------------- 915
Cdd:PRK11281 94 AKLRQAQAELEALKDDNDEETRET-LSTLS---LRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQtqperaqaalyans 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 916 LKTQQMNNDL-------EKLSHELeKIGLNKERLLCDEQSSDDRyKLLE--SKLESTLKKSLEIKEEKIAALEARLeest 986
Cdd:PRK11281 170 QRLQQIRNLLkggkvggKALRPSQ-RVLLQAEQALLNAQNDLQR-KSLEgnTQLQDLLQKQRDYLTARIQRLEHQL---- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 987 nlnqQLRQELKTVKKnyeaLKQRQEEERMVQNPpprkgEENQSVNkwekENQETTREL---LKVKDRLIEVERNNATLQA 1063
Cdd:PRK11281 244 ----QLLQEAINSKR----LTLSEKTVQEAQSQ-----DEAARIQ----ANPLVAQELeinLQLSQRLLKATEKLNTLTQ 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1064 EKQALKTQLKQLETQNNNLQAQILAL------------QRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA-- 1129
Cdd:PRK11281 307 QNLRVKNWLDRLTQSERNIKEQISVLkgslllsrilyqQQQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAyi 386
|
410
....*....|....*
gi 2024492573 1130 -QLLIQQSALENEKE 1143
Cdd:PRK11281 387 dKLEAGHKSEVTDEV 401
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
746-987 |
3.56e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.77 E-value: 3.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 746 ASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELvisSKRLEQLEKENKLLEQETS 825
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRAL---EQELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 826 QLEKDKKQLEKENKRLRQQAEikdsTLEENNVKINHLEKENKSLFKQIAVYkescvrLKELEMENKELVKRASIDKKTLV 905
Cdd:COG4942 94 ELRAELEAQKEELAELLRALY----RLGRQPPLALLLSPEDFLDAVRRLQY------LKYLAPARREQAEELRADLAELA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 906 TLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLcdeQSSDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEES 985
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELA-ELQQEAEELEALIARLEAEAAAA 239
|
..
gi 2024492573 986 TN 987
Cdd:COG4942 240 AE 241
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
132-651 |
4.35e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.33 E-value: 4.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 132 AVQCQKKEEFIERIQHLDfDTRAAVAAHIQEVTQNQENVFDlqwmdvivfTQDSVEPLLKNMTLHLRRLVDERDEHLETI 211
Cdd:COG1196 305 ARLEERRRELEERLEELE-EELAELEEELEELEEELEELEE---------ELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 212 IELSEDRDSLHLLPQASAAQSpcgspgLKHTESKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQ 291
Cdd:COG1196 375 AEAEEELEELAEELLEALRAA------AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 292 QENKNLLSDARSARVYRDEL-DILREKAIRVDKLESEVGRYKERLHDMEFYKARVEELMEDNQVMLETKRMFEDQVKTLQ 370
Cdd:COG1196 449 EEEAELEEEEEALLELLAELlEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 371 CRSDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEEN-------MALEMAQKQSMDESLHLGWELEQINRFTDHSE 443
Cdd:COG1196 529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIRARAALAAALARGAIGAAVDLVASDL 608
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 444 VSHK------SLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQE 517
Cdd:COG1196 609 READaryyvlGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 518 KQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKEnkilhESIK 597
Cdd:COG1196 689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP-----PDLE 763
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 598 ETSSKLNKLEFEIKqvrkEM--------EHYKEKAERAEELENELHHLEKENELLQKKIANL 651
Cdd:COG1196 764 ELERELERLEREIE----ALgpvnllaiEEYEELEERYDFLSEQREDLEEARETLEEAIEEI 821
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
596-1167 |
4.89e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 54.91 E-value: 4.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 596 IKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKL 675
Cdd:PRK01156 144 ISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERL 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 676 KKTLDSLKNLSFQL-ESLEKENSQLDEENlelrRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLElmKASFKKSERL 754
Cdd:PRK01156 224 SIEYNNAMDDYNNLkSALNELSSLEDMKN----RYESEIKTAESDLSMELEKNNYYKELEERHMKIIN--DPVYKNRNYI 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 755 eVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLEsenqTLQKNLEELVISSKRLEQLEKENKLLE----------QET 824
Cdd:PRK01156 298 -NDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLS----VLQKDYNDYIKKKSRYDDLNNQILELEgyemdynsylKSI 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 825 SQLEKDKKQLEKENKRLRQQ-----------AEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKE----LEME 889
Cdd:PRK01156 373 ESLKKKIEEYSKNIERMSAFiseilkiqeidPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRnmemLNGQ 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 890 NKELVKRASIDKKTLVTLREDLVNEKlktQQMNNDLEKLSHELEKIGlNKERLLCDEQSSDDRYKLLESKLESTLKKSLE 969
Cdd:PRK01156 453 SVCPVCGTTLGEEKSNHIINHYNEKK---SRLEEKIREIEIEVKDID-EKIVDLKKRKEYLESEEINKSINEYNKIESAR 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 970 IKEEKIAALEARLEESTNLNQQLRQELKTVKknYEALKQRQEE--ERMVQnppprkgEENQSVNKWEKENQETTRELLKV 1047
Cdd:PRK01156 529 ADLEDIKIKINELKDKHDKYEEIKNRYKSLK--LEDLDSKRTSwlNALAV-------ISLIDIETNRSRSNEIKKQLNDL 599
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1048 KDRLIEVERNnatLQAEKQALKTQLKQLETQNNNLQAQ---ILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1124
Cdd:PRK01156 600 ESRLQEIEIG---FPDDKSYIDKSIREIENEANNLNNKyneIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRI 676
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 2024492573 1125 MNQNAQLLIQQSALENekegVLKELEDLKSLYDSLLKDHEKLE 1167
Cdd:PRK01156 677 NDIEDNLKKSRKALDD----AKANRARLESTIEILRTRINELS 715
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
705-1123 |
5.64e-07 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 54.95 E-value: 5.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 705 ELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMK-------ASFKKseRLEVSYQGLDTENQRLQKALENSNK 777
Cdd:pfam15818 15 ELRMRREAETQYEEQIGKIIVETQELKWQKETLQNQKETLAkqhkeamAVFKK--QLQMKMCALEEEKGKYQLATEIKEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 778 KIQQLEGELQDLESENQTLQKNLEELvisskrleqlekENKLLEQETSQLEKDKKQLEKEnkrlRQQAEIKDS--TLEEN 855
Cdd:pfam15818 93 EIEGLKETLKALQVSKYSLQKKVSEM------------EQKLQLHLLAKEDHHKQLNEIE----KYYATITGQfgLVKEN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 856 NVKINHLEKENKSLFKQIAVYKEScvRLKELEMENKELVKRASIDKKTLVT----LREDLVNEKLKTQQMNNDLEKLSHE 931
Cdd:pfam15818 157 HGKLEQNVQEAIQLNKRLSALNKK--QESEICSLKKELKKVTSDLIKSKVTcqykMGEENINLTIKEQKFQELQERLNME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 932 LEkigLNKerllcdeqssddrykllesKLESTLKKSLEIKEEKIAALEAR---LEESTNLNQQLRQELKTVKKNYEALKQ 1008
Cdd:pfam15818 235 LE---LNK-------------------KINEEITHIQEEKQDIIISFQHMqqlLQQQTQANTEMEAELKALKENNQTLER 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1009 RQEEERMVQNPPPRK-----GEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1083
Cdd:pfam15818 293 DNELQREKVKENEEKflnlqNEHEKALGTWKKHVEELNGEINEIKNELSSLKETHIKLQEHYNKLCNQKKFEEDKKFQNV 372
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 2024492573 1084 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTS 1123
Cdd:pfam15818 373 PEVNNENSEMSTEKSENLIIQKYNSEQEIREENTKSFCSD 412
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
610-743 |
5.83e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 54.48 E-value: 5.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 610 IKQVRKEMEHyKEKAERAEELENELHHLEKENELLQKKIANLSitcEKIEALEKENSDL-------DIENRKLKKTLDSL 682
Cdd:COG2433 378 IEEALEELIE-KELPEEEPEAEREKEHEERELTEEEEEIRRLE---EQVERLEAEVEELeaeleekDERIERLERELSEA 453
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 683 KNLSFQLESLEKENSQLDEENLELRRRIEsskctsikmaQLQLENKELESEKEQLKKSLEL 743
Cdd:COG2433 454 RSEERREIRKDREISRLDREIERLERELE----------EERERIEELKRKLERLKELWKL 504
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
526-781 |
6.49e-07 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 53.66 E-value: 6.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 526 NLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTI---------------ASLRQRSQISA-----EAQMKEI 585
Cdd:pfam15905 55 KVKSLELKKKSQKNLKESKDQKELEKEIRALVQERGEQDKRLqaleeelekveaklnAAVREKTSLSAsvaslEKQLLEL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 586 EKENKILHESIKETSS--KLNKLEFEIKQVRKEME-HYKEKAERAEELENELHHLEKENELLQKKIANLSitcEKIEALE 662
Cdd:pfam15905 135 TRVNELLKAKFSEDGTqkKMSSLSMELMKLRNKLEaKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLE---EKLVSTE 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 663 KENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDE-------ENLELRRRIESSKCTSIKMAQLQLEN-KELESEK 734
Cdd:pfam15905 212 KEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEEllkekndEIESLKQSLEEKEQELSKQIKDLNEKcKLLESEK 291
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2024492573 735 EQLKKslelmkasfkkseRLEVSYQGLDTENQRLQKAL---ENSNKKIQQ 781
Cdd:pfam15905 292 EELLR-------------EYEEKEQTLNAELEELKEKLtleEQEHQKLQQ 328
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
791-1143 |
6.64e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 54.36 E-value: 6.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 791 SENQTLQKnLEELVISSKRLEQLEKENKL--LEQETSQLEKDKKQLEKENKRLRQQAEikdstleennvkinhlEKENKS 868
Cdd:pfam17380 266 TENEFLNQ-LLHIVQHQKAVSERQQQEKFekMEQERLRQEKEEKAREVERRRKLEEAE----------------KARQAE 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 869 LFKQIAVYKEScvrlKELEME-NKELVKRASIDKKtlvtlREdlvNEKLKTQQMNNDLEKLsHELEKIGLNKER---LLC 944
Cdd:pfam17380 329 MDRQAAIYAEQ----ERMAMErERELERIRQEERK-----RE---LERIRQEEIAMEISRM-RELERLQMERQQkneRVR 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 945 DEQSSDDRYKLLESKLESTLKKSL-EIKEEKIAALEARLEESTNLNQQLRQELKTVKKnyEALKQRQEEERMvqnpppRK 1023
Cdd:pfam17380 396 QELEAARKVKILEEERQRKIQQQKvEMEQIRAEQEEARQREVRRLEEERAREMERVRL--EEQERQQQVERL------RQ 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1024 GEENQSVNKWEKENQETTRELLKVKDRLI---EVERNNATLQAEKQALKTQLKQLETQNNNL----QAQILALQRQTVSL 1096
Cdd:pfam17380 468 QEEERKRKKLELEKEKRDRKRAEEQRRKIlekELEERKQAMIEEERKRKLLEKEMEERQKAIyeeeRRREAEEERRKQQE 547
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 2024492573 1097 QEQNTTLQTQNAKLQVENSTLNSqstslMNQNAQLLIQqsALENEKE 1143
Cdd:pfam17380 548 MEERRRIQEQMRKATEERSRLEA-----MEREREMMRQ--IVESEKA 587
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
501-858 |
6.69e-07 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 54.31 E-value: 6.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 501 QRLNKKIEELEKE---IVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRenleRQIKLLEQENERSNQTIASLRQRSQIs 577
Cdd:pfam05622 17 HELDQQVSLLQEEknsLQQENKKLQERLDQLESGDDSGTPGGKKYLLLQ----KQLEQLQEENFRLETARDDYRIKCEE- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 578 AEAQMKEIEKENKILHES-------------IKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELL 644
Cdd:pfam05622 92 LEKEVLELQHRNEELTSLaeeaqalkdemdiLRESSDKVKKLEATVETYKKKLEDLGDLRRQVKLLEERNAEYMQRTLQL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 645 QKKIANLSITCEKIEALEKENSDL----DIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKCTSIKM 720
Cdd:pfam05622 172 EEELKKANALRGQLETYKRQVQELhgklSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTLRETNEELRCAQLQQ 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 721 AQLQLENKELESEKEQLKK-SLELMKASFK-KSERLEVSYQGLD-----TENQR---LQKALENSNKKIQQLEGELQ--- 787
Cdd:pfam05622 252 AELSQADALLSPSSDPGDNlAAEIMPAEIReKLIRLQHENKMLRlgqegSYRERlteLQQLLEDANRRKNELETQNRlan 331
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 788 ----DLESENQTLQKNLEELVI----SSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVK 858
Cdd:pfam05622 332 qrilELQQQVEELQKALQEQGSkaedSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRK 410
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
630-1352 |
8.11e-07 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 54.44 E-value: 8.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 630 LENELHHLEKENELLQKkianlsitcekiealekensDLDIENRKLKKTLDSLKNlsFQLESLEKENSQLDEENLELRRR 709
Cdd:pfam10174 1 LQAQLRDLQRENELLRR--------------------ELDIKESKLGSSMNSIKT--FWSPELKKERALRKEEAARISVL 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 710 IESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERlevsyqglDTENQRLQKALENSNkkIQQLEGELQDL 789
Cdd:pfam10174 59 KEQYRVTQEENQHLQLTIQALQDELRAQRDLNQLLQQDFTTSPV--------DGEDKFSTPELTEEN--FRRLQSEHERQ 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 790 ESENQTLQKNLEELVISSKRLEQL-----EKENKLLEQETSQlEKDKKQLEKENKRLRQQAEIkDSTLEENNVKINHLEK 864
Cdd:pfam10174 129 AKELFLLRKTLEEMELRIETQKQTlgardESIKKLLEMLQSK-GLPKKSGEEDWERTRRIAEA-EMQLGHLEVLLDQKEK 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 865 ENKSLfkqiavyKESCVRLKELEMENKELvkrasidkKTLVTLREDLVNEKLKTQQMNNDLEklsheLEKIGLNKERLLC 944
Cdd:pfam10174 207 ENIHL-------REELHRRNQLQPDPAKT--------KALQTVIEMKDTKISSLERNIRDLE-----DEVQMLKTNGLLH 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 945 DEQSSDD---------RYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQR----QE 1011
Cdd:pfam10174 267 TEDREEEikqmevyksHSKFMKNKID-QLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRaailQT 345
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1012 EERMVQNpppRKGEENQSVNKWEKENQETTR-------ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA 1084
Cdd:pfam10174 346 EVDALRL---RLEEKESFLNKKTKQLQDLTEekstlagEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKE 422
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1085 QILALQRQTV-----------SLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALE---NEKEGVLKEL- 1149
Cdd:pfam10174 423 RVKSLQTDSSntdtalttleeALSEKERIIERLKEQREREDRERLEELESLKKENKDLKEKVSALQpelTEKESSLIDLk 502
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1150 EDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHK--DLEDRYSQLLKQ-----------KVQLE 1216
Cdd:pfam10174 503 EHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTnpEINDRIRLLEQEvarykeesgkaQAEVE 582
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1217 ELEKVLK-TEQEKMLQQNEKHETVAAEYKKLRDENDRLA---HTHDQLLKEN-EVLQTDHKNLKTLLNNSKLGQ-TQLEA 1290
Cdd:pfam10174 583 RLLGILReVENEKNDKDKKIAELESLTLRQMKEQNKKVAnikHGQQEMKKKGaQLLEEARRREDNLADNSQQLQlEELMG 662
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 1291 EFSKLREEYQLLDIKctkisnqcelLSQLKGNMEEENRHLldqiQTLMLQNRTLLEQNMESK 1352
Cdd:pfam10174 663 ALEKTRQELDATKAR----------LSSTQQSLAEKDGHL----TNLRAERRKQLEEILEMK 710
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
258-836 |
8.18e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 54.26 E-value: 8.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 258 KIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQEnknllsdarsarvyrdeldiLREKAIRVDKLESEVGRYKERLHD 337
Cdd:TIGR04523 240 EINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE--------------------LEQNNKKIKELEKQLNQLKSEISD 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 338 MEFYKArveelmednqvmletkrmfedqvktlqcrSDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEMA 417
Cdd:TIGR04523 300 LNNQKE-----------------------------QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 418 QKQSMDESLHLGWELEQINrftdhsevshkslglevteltsSRLLKLEKENQSLLKTVEELRSTMDDSvggnSSRIVKME 497
Cdd:TIGR04523 351 LTNSESENSEKQRELEEKQ----------------------NEIEKLKKENQSYKQEIKNLESQINDL----ESKIQNQE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 498 KENQRLNKKI-------EELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETL---RENLERQIKLLEQENERSNQTI 567
Cdd:TIGR04523 405 KLNQQKDEQIkklqqekELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLdntRESLETQLKVLSRSINKIKQNL 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 568 ASLRQR-----SQISA-EAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEElenelhhlEKEN 641
Cdd:TIGR04523 485 EQKQKElkskeKELKKlNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF--------ELKK 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 642 ELLQKKIANLSitcEKIEALEKENSDLDIENRKLKKTLDslkNLSFQLESLEKENSQLDEENLELRRRIESSKCTSIKma 721
Cdd:TIGR04523 557 ENLEKEIDEKN---KEIEELKQTQKSLKKKQEEKQELID---QKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEK-- 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 722 qLQLENKELESEKEQLKKSLELMKASFKKserLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQknle 801
Cdd:TIGR04523 629 -LSSIIKNIKSKKNKLKQEVKQIKETIKE---IRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRM---- 700
|
570 580 590
....*....|....*....|....*....|....*
gi 2024492573 802 elvISSKRLEQLEKENKLLEQETSQLEKDKKQLEK 836
Cdd:TIGR04523 701 ---IRIKDLPKLEEKYKEIEKELKKLDEFSKELEN 732
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
719-878 |
8.61e-07 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 53.68 E-value: 8.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 719 KMAQLQLENKELESEKEQLKKSLElmkasfkkseRLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQK 798
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELD----------ALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 799 NLEELVISSKR-------------------------------------LEQLEKENKLLEQETSQLEKDKKQLEKENKRL 841
Cdd:COG3883 87 ELGERARALYRsggsvsyldvllgsesfsdfldrlsalskiadadadlLEELKADKAELEAKKAELEAKLAELEALKAEL 166
|
170 180 190
....*....|....*....|....*....|....*..
gi 2024492573 842 RQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKE 878
Cdd:COG3883 167 EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEA 203
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
505-1085 |
8.62e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.54 E-value: 8.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 505 KKIEELEKEIVQEKQ---SLQDNQNLSKDLMKEKEQLEKkFETLRENL-----ERQIKLLEQENERSNQTIASLRQRSQI 576
Cdd:COG4913 235 DDLERAHEALEDAREqieLLEPIRELAERYAAARERLAE-LEYLRAALrlwfaQRRLELLEAELEELRAELARLEAELER 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 577 sAEAQMKEIEKENKILHESIKETS-SKLNKLEFEIKQVRKEMEHYKEKAERAEELENELH----HLEKENELLQKKIANL 651
Cdd:COG4913 314 -LEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAALGlplpASAEEFAALRAEAAAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 652 SITCEKI-EALEKENSDLDIENRKLKKTLDSLKNlsfQLESLEKENSQLDEENLELRRRIESSkcTSIKMAQLQL--ENK 728
Cdd:COG4913 393 LEALEEElEALEEALAEAEAALRDLRRELRELEA---EIASLERRKSNIPARLLALRDALAEA--LGLDEAELPFvgELI 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 729 ELESEKEQLKKSLELMKASFKKS-------------------ERLEVSYQGLDT--ENQRLQKALENSnkkiqqLEGElq 787
Cdd:COG4913 468 EVRPEEERWRGAIERVLGGFALTllvppehyaaalrwvnrlhLRGRLVYERVRTglPDPERPRLDPDS------LAGK-- 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 788 dLESENQTLQKNLEELVISSKRL------EQLEKENK------LLEQETSQLEKDKkqlekeNKRLRQQAEIKDSTLEen 855
Cdd:COG4913 540 -LDFKPHPFRAWLEAELGRRFDYvcvdspEELRRHPRaitragQVKGNGTRHEKDD------RRRIRSRYVLGFDNRA-- 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 856 nvKINHLEKENKSLFKQIAVYKEscvRLKELEMENKELVKRASIDKKtLVTLREDLVneklktqqmnnDLEKLSHELEKI 935
Cdd:COG4913 611 --KLAALEAELAELEEELAEAEE---RLEALEAELDALQERREALQR-LAEYSWDEI-----------DVASAEREIAEL 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 936 GLNKERLlcdEQSSDDrykllesklestlkksLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERM 1015
Cdd:COG4913 674 EAELERL---DASSDD----------------LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD 734
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1016 VQNPPPRKGEEnqsvnkWEKENQETTRELLKVKDRLIEVERNnatLQAEKQALKTQLKQLETQNNNLQAQ 1085
Cdd:COG4913 735 RLEAAEDLARL------ELRALLEERFAAALGDAVERELREN---LEERIDALRARLNRAEEELERAMRA 795
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
248-741 |
9.42e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 54.28 E-value: 9.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 248 LSVELADAKAKIRRLRQEIEEKNEQFLDYKQEL------ERVETELRRLQQE----NKNLLSDARSARVYRDELDILREK 317
Cdd:TIGR00606 596 LNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEieksSKQRAMLAGATAVYSQFITQLTDE 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 318 AI-------RVDKLESEVGRYKERLHDMEFYKARVEELMEDNQVMLETKRmfEDQVKTLQCRSDKLHVVEKENLQLKAKL 390
Cdd:TIGR00606 676 NQsccpvcqRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRR--DEMLGLAPGRQSIIDLKEKEIPELRNKL 753
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 391 HEMEMERDMDRKKIEElMEENMALEMAQKQSMDESL-------HLGWELEQINRFTDH--SEVSHKSLGLEVTEL----- 456
Cdd:TIGR00606 754 QKVNRDIQRLKNDIEE-QETLLGTIMPEEESAKVCLtdvtimeRFQMELKDVERKIAQqaAKLQGSDLDRTVQQVnqekq 832
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 457 --------TSSRLLKLEKENQSLLKTVEELRSTMDD------SVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQ 522
Cdd:TIGR00606 833 ekqheldtVVSKIELNRKLIQDQQEQIQHLKSKTNElkseklQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDS 912
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 523 DNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKILHESIKETSSK 602
Cdd:TIGR00606 913 PLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKH 992
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 603 LNKLEFEIKQVRKEMEHYKEKAERAEE------LENELHHLEKENELLQKKIANLSITCEKiEALEKENSDLDIENRKLK 676
Cdd:TIGR00606 993 QEKINEDMRLMRQDIDTQKIQERWLQDnltlrkRENELKEVEEELKQHLKEMGQMQVLQMK-QEHQKLEENIDLIKRNHV 1071
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 677 KTLDSLKNLSFQLESLEKENSQLDEENLElrrriESSKCTSIKMAQLQLENKELESEKEQLKKSL 741
Cdd:TIGR00606 1072 LALGRQKGYEKEIKHFKKELREPQFRDAE-----EKYREMMIVMRTTELVNKDLDIYYKTLDQAI 1131
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
766-1383 |
1.01e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 54.28 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 766 QRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQa 845
Cdd:TIGR00606 189 ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKL- 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 846 eikDSTLEENNVKINHLEKENKSL-FKQIAVYKESCVRLKELEMENKELVKRAsidKKTLVTLREDLVNEKLKTQQMNND 924
Cdd:TIGR00606 268 ---DNEIKALKSRKKQMEKDNSELeLKMEKVFQGTDEQLNDLYHNHQRTVREK---ERELVDCQRELEKLNKERRLLNQE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 925 LEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLE-STLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNy 1003
Cdd:TIGR00606 342 KTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLElDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSK- 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1004 EALKQRQEEERMVQNPPPRKGEENQSVNKWEKENQettreLLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNlq 1083
Cdd:TIGR00606 421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEE-----LKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKN-- 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1084 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL----------MNQNAQLLIQQSALENEKEGVLKELEDLK 1153
Cdd:TIGR00606 494 SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRtqmemltkdkMDKDEQIRKIKSRHSDELTSLLGYFPNKK 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1154 SLYDSLLKDHEKLEHLHERQAS---EYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLL---KQKVQLEELEKVLKTEQE 1227
Cdd:TIGR00606 574 QLEDWLHSKSKEINQTRDRLAKlnkELASLEQNKNHINNELESKEEQLSSYEDKLFDVCgsqDEESDLERLKEEIEKSSK 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1228 KMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKCT 1307
Cdd:TIGR00606 654 QRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAP 733
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 1308 KISNQCELLSQLKGNMEEENRHLLDQIQTL---MLQNRTLLEQNMESKDLFHVEQRQyIDKLNELRRQKEKLEEKIMDQ 1383
Cdd:TIGR00606 734 GRQSIIDLKEKEIPELRNKLQKVNRDIQRLkndIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELKDVERKIAQQ 811
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
268-586 |
1.02e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 53.97 E-value: 1.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 268 EKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARvyrdELDILREKAIRV--DKLESEVGRYKERLHDMEfyKARV 345
Cdd:pfam17380 288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKAR----QAEMDRQAAIYAeqERMAMERERELERIRQEE--RKRE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 346 EELMEDNQVMLETKRMFEdqVKTLQCRSDKLHVVEKENLQLKAKLHEMEMERdmdRKKIEELMEENMALEMAQKQSMDES 425
Cdd:pfam17380 362 LERIRQEEIAMEISRMRE--LERLQMERQQKNERVRQELEAARKVKILEEER---QRKIQQQKVEMEQIRAEQEEARQRE 436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 426 LHL-----GWELEQINRftDHSEVSHKSLGLEVTELTSSR-LLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKE 499
Cdd:pfam17380 437 VRRleeerAREMERVRL--EEQERQQQVERLRQQEEERKRkKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERK 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 500 NQRLNKKIEELEKEIVQEKQSLQDNQNLSKDL-MKEKEQLEKKFETLRENLERqIKLLEQENERSNQTIASLRQRSQISA 578
Cdd:pfam17380 515 RKLLEKEMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSR-LEAMEREREMMRQIVESEKARAEYEA 593
|
....*...
gi 2024492573 579 EAQMKEIE 586
Cdd:pfam17380 594 TTPITTIK 601
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
580-928 |
1.06e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 53.78 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 580 AQMKEIE----KENK-----ILHEsiketsskLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKenellqkkian 650
Cdd:PRK05771 4 VRMKKVLivtlKSYKdevleALHE--------LGVVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRS----------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 651 lsitcekieALEKENSDLDIENRKLKKTLDSLKNLSFQ-LESLEKENSQLDEENLELRRRIesskctsikmaqlqlenKE 729
Cdd:PRK05771 65 ---------YLPKLNPLREEKKKVSVKSLEELIKDVEEeLEKIEKEIKELEEEISELENEI-----------------KE 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 730 LESEKEQLK--KSLELMKASFKKSERLEVSYQGLDTENQRLQKALE--------------------NSNKKIQQLEGELQ 787
Cdd:PRK05771 119 LEQEIERLEpwGNFDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESdvenveyistdkgyvyvvvvVLKELSDEVEEELK 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 788 DLESENQtlqkNLEELVISSKRLEQLEKENKLLEQETSQLEKD-KKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKEN 866
Cdd:PRK05771 199 KLGFERL----ELEEEGTPSELIREIKEELEEIEKERESLLEElKELAKKYLEELLALYEYLEIELERAEALSKFLKTDK 274
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 867 kslfkqiAVYKESCV---RLKELemenKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKL 928
Cdd:PRK05771 275 -------TFAIEGWVpedRVKKL----KELIDKATGGSAYVEFVEPDEEEEEVPTKLKNPKFIKP 328
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
722-1018 |
1.24e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 53.48 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 722 QLQLENKELESEKEQLKKSLELMKA----SFKKSERLEVSYQGLDTE--------------NQRLQKALENSNKKIQQLE 783
Cdd:COG3206 102 KLNLDEDPLGEEASREAAIERLRKNltvePVKGSNVIEISYTSPDPElaaavanalaeaylEQNLELRREEARKALEFLE 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 784 GELQDLESENQTLQKNLEELvISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLe 863
Cdd:COG3206 182 EQLPELRKELEEAEAALEEF-RQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL- 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 864 kenkslfKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLRedlvneklktQQMNNDLEKLSHELEKIglnkerll 943
Cdd:COG3206 260 -------LQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALR----------AQIAALRAQLQQEAQRI-------- 314
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 944 cdEQSSDDRYKLLESKLESTlkksleikEEKIAALEARLEESTNLNQQLRQ---ELKTVKKNYEALKQRQEEERMVQN 1018
Cdd:COG3206 315 --LASLEAELEALQAREASL--------QAQLAQLEARLAELPELEAELRRlerEVEVARELYESLLQRLEEARLAEA 382
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
495-713 |
1.52e-06 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 53.32 E-value: 1.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 495 KMEKENQRLNKKIEELEKEIVQEKQSLQDN----QNLSKDLMKEK-----EQLEKKFETLRENLERQIKLL--------E 557
Cdd:pfam06160 183 KLEEETDALEELMEDIPPLYEELKTELPDQleelKEGYREMEEEGyalehLNVDKEIQQLEEQLEENLALLenleldeaE 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 558 QENERSNQTIASLRQRSQISAEAQmKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHL 637
Cdd:pfam06160 263 EALEEIEERIDQLYDLLEKEVDAK-KYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGLEKQLEEL 341
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024492573 638 EKENELLQKKIANLSIT-CEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESS 713
Cdd:pfam06160 342 EKRYDEIVERLEEKEVAySELQEELEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLELREIKRLVEKS 418
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
495-1012 |
1.81e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 53.43 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 495 KMEKENQRLNKKIEELEKE------IVQEKQSLQDNQNLSKDLMKEKEQLEKKFE---TLRENLERQiKLLEQENERSNQ 565
Cdd:TIGR00618 308 QAQRIHTELQSKMRSRAKLlmkraaHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEvatSIREISCQQ-HTLTQHIHTLQQ 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 566 TIASLRQRSQISAEAQMKEIEKENKIL-----------HESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENEL 634
Cdd:TIGR00618 387 QKTTLTQKLQSLCKELDILQREQATIDtrtsafrdlqgQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 635 HHLEKENELLQKKIANLSITcEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSK 714
Cdd:TIGR00618 467 SLKEREQQLQTKEQIHLQET-RKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE 545
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 715 CTSikmAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQ 794
Cdd:TIGR00618 546 DVY---HQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ 622
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 795 TLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKdkkqlEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIA 874
Cdd:TIGR00618 623 PEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQ-----ERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKE 697
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 875 VYKESCVRLKELEMENKELVK------RASIDKKTLVTLREDLVNEKLKTQQMNNDlEKLSHELEKIGLNKERLLCDEQs 948
Cdd:TIGR00618 698 MLAQCQTLLRELETHIEEYDRefneieNASSSLGSDLAAREDALNQSLKELMHQAR-TVLKARTEAHFNNNEEVTAALQ- 775
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 949 SDDRYKLLESKLESTlKKSLEIKEEKIAALEARLEESTNLNQQLRQ-ELKTVKKNYEALKQRQEE 1012
Cdd:TIGR00618 776 TGAELSHLAAEIQFF-NRLREEDTHLLKTLEAEIGQEIPSDEDILNlQCETLVQEEEQFLSRLEE 839
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
189-782 |
2.27e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 52.82 E-value: 2.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 189 LLKNMTLHLRRLVDERDEHLETIIELSEDRDSLHLLPQASAAQSPCGSPGLKHTESKQHLSVE----LADAKAKIRRLRQ 264
Cdd:pfam05557 32 LEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEkesqLADAREVISCLKN 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 265 EIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDEL----DILREKAIRVDKLESEVGRY---KERLHD 337
Cdd:pfam05557 112 ELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLekqqSSLAEAEQRIKELEFEIQSQeqdSEIVKN 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 338 MEFYKARVEELmednqvmletkrmfEDQVKTLQCRSDKLHVVEKENLQLKAKLHEMEMERDmdrkKIEELMEENMALEMa 417
Cdd:pfam05557 192 SKSELARIPEL--------------EKELERLREHNKHLNENIENKLLLKEEVEDLKRKLE----REEKYREEAATLEL- 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 418 qkqsmdESLHLGWEL-EQINRFTDHsevshkSLGLEVTELTSSRLLKLEKENqsllKTVEELRSTMDDSVGGNSSRIVKM 496
Cdd:pfam05557 253 ------EKEKLEQELqSWVKLAQDT------GLNLRSPEDLSRRIEQLQQRE----IVLKEENSSLTSSARQLEKARREL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 497 EKENQRLNKKIEELEKEivqekqsLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENersnqtiASLRQRSQI 576
Cdd:pfam05557 317 EQELAQYLKKIEDLNKK-------LKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSN-------YSPQLLERI 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 577 SAEAQMkeiekenkilhesIKETSSKLNKLEFEIKQVRKEMEHYKekaERAEELENELHHLEKENELlqkkiANLSITCE 656
Cdd:pfam05557 383 EEAEDM-------------TQKMQAHNEEMEAQLSVAEEELGGYK---QQAQTLERELQALRQQESL-----ADPSYSKE 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 657 KIEALEKENSDLDIENRKLKKTLDSLKnlsfqlESLEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQ 736
Cdd:pfam05557 442 EVDSLRRKLETLELERQRLREQKNELE------MELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIER 515
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 2024492573 737 LKKSLELMKASFKKSERL-EVSYQGLDTENQRLQKALENSNKKIQQL 782
Cdd:pfam05557 516 LKRLLKKLEDDLEQVLRLpETTSTMNFKEVLDLRKELESAELKNQRL 562
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
504-664 |
2.28e-06 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 52.55 E-value: 2.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 504 NKKIEELEKEIVQEKQSLQDNQNlskDLMKEKEQLEKKFETLR---ENLERQIKLLEQENERSNQTIASLRQRSQisaea 580
Cdd:COG2433 387 EKELPEEEPEAEREKEHEERELT---EEEEEIRRLEEQVERLEaevEELEAELEEKDERIERLERELSEARSEER----- 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 581 qmKEIEKENKIlhesiketssklNKLEFEIKQVRKEMEhykEKAERAEELENELHHLEKENELLQ-------KKIANLsi 653
Cdd:COG2433 459 --REIRKDREI------------SRLDREIERLERELE---EERERIEELKRKLERLKELWKLEHsgelvpvKVVEKF-- 519
|
170
....*....|.
gi 2024492573 654 TCEKIEALEKE 664
Cdd:COG2433 520 TKEAIRRLEEE 530
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
978-1216 |
2.42e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 52.71 E-value: 2.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 978 LEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERmvqnppprkgEENQSVNkwekenqeTTRELLKVKDRLIEVERN 1057
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFR----------QKNGLVD--------LSEEAKLLLQQLSELESQ 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1058 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSA 1137
Cdd:COG3206 228 LAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ 306
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 1138 LENEKEGVLKELEdlkSLYDSLLKDHEKLEhlheRQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLLKQKVQLE 1216
Cdd:COG3206 307 LQQEAQRILASLE---AELEALQAREASLQ----AQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
349-650 |
2.46e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 52.98 E-value: 2.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 349 MEDNQVMLETKRMF--EDQVKTLQcrsdklhvvEKENLQLKAKLHEMEMERDMDRKKIEElmEENMALEMAQKQSMDESL 426
Cdd:PLN02939 140 AEKNILLLNQARLQalEDLEKILT---------EKEALQGKINILEMRLSETDARIKLAA--QEKIHVEILEEQLEKLRN 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 427 HLGWELEqinrfTDHSEVSHKSLGLEVteltssrllkLEKENQSLLKTVEELRSTMDdSVGGNSSRIVKMEKENQRLNKK 506
Cdd:PLN02939 209 ELLIRGA-----TEGLCVHSLSKELDV----------LKEENMLLKDDIQFLKAELI-EVAETEERVFKLEKERSLLDAS 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 507 IEELE------KEIVQEKQSLQDN------QNLSKDLMKEKEQLEKKFETLREN--LERQIKLLEQENERSN-------- 564
Cdd:PLN02939 273 LRELEskfivaQEDVSKLSPLQYDcwwekvENLQDLLDRATNQVEKAALVLDQNqdLRDKVDKLEASLKEANvskfssyk 352
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 565 -----QTIASLRQRSQISAEaqmkEIEKENKILHESIKETSSKLNKLEFEIKqvRKEMEHYkekaerAEELENELHH--- 636
Cdd:PLN02939 353 vellqQKLKLLEERLQASDH----EIHSYIQLYQESIKEFQDTLSKLKEESK--KRSLEHP------ADDMPSEFWSril 420
|
330
....*....|....
gi 2024492573 637 LEKENELLQKKIAN 650
Cdd:PLN02939 421 LLIDGWLLEKKISN 434
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
583-888 |
2.60e-06 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 51.74 E-value: 2.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 583 KEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSITCEKIEAle 662
Cdd:pfam15905 31 KQKAAESQPNLNNSKDASTPATARKVKSLELKKKSQKNLKESKDQKELEKEIRALVQERGEQDKRLQALEEELEKVEA-- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 663 kensdldienrKLKKTLDSLKNLSFQLESLEKENSQLDEENlELRRRIESSKCTSIKMAQLQLENKELESEKEQLkksle 742
Cdd:pfam15905 109 -----------KLNAAVREKTSLSASVASLEKQLLELTRVN-ELLKAKFSEDGTQKKMSSLSMELMKLRNKLEAK----- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 743 lMKASFKKSERLEVSYQgldtenqRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQ 822
Cdd:pfam15905 172 -MKEVMAKQEGMEGKLQ-------VTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKL 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 823 ETSQLEKDKKQLEKENKRLRQQAEIKDSTLEEN----NVKINHLEKENKSLFKQIAVYKEScvRLKELEM 888
Cdd:pfam15905 244 DIAQLEELLKEKNDEIESLKQSLEEKEQELSKQikdlNEKCKLLESEKEELLREYEEKEQT--LNAELEE 311
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
464-1390 |
2.70e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 52.65 E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 464 LEKENQSLLKTVEELRSTMddsvggnssRIVKMEKENQRLNKKIEELEKEIVQEKQS----------------LQDNQNL 527
Cdd:PRK04863 221 LLPENSGVRKAFQDMEAAL---------RENRMTLEAIRVTQSDRDLFKHLITESTNyvaadymrhanerrvhLEEALEL 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 528 SKDLMKEKEQLEKKFETLRE------NLERQIKLLEQENERsnqtiASLRQRSQISAEAQMKEIEKenkilhesikeTSS 601
Cdd:PRK04863 292 RRELYTSRRQLAAEQYRLVEmarelaELNEAESDLEQDYQA-----ASDHLNLVQTALRQQEKIER-----------YQA 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 602 KLNKLEFeikQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSitcEKIEALEKENsdldIENRKLKKTLDS 681
Cdd:PRK04863 356 DLEELEE---RLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQ---QALDVQQTRA----IQYQQAVQALER 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 682 -----------LKNLSFQLESLEKENSQLDEENLELRRRIESSkctsikmaqlqlenkelESEKEQLKKSLELMKASFKK 750
Cdd:PRK04863 426 akqlcglpdltADNAEDWLEEFQAKEQEATEELLSLEQKLSVA-----------------QAAHSQFEQAYQLVRKIAGE 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 751 SERLEVSYQGLDTENQ-RLQKALENSnkkIQQLEGELQDLESENQtLQKNLEELVIS-SKRLEQLEKENKLLEQETSQLE 828
Cdd:PRK04863 489 VSRSEAWDVARELLRRlREQRHLAEQ---LQQLRMRLSELEQRLR-QQQRAERLLAEfCKRLGKNLDDEDELEQLQEELE 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 829 KDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKenksLFKQIAVYKESCVRLKelEMENKELVKRASIDKKTLVTLr 908
Cdd:PRK04863 565 ARLESLSESVSEARERRMALRQQLEQLQARIQRLAA----RAPAWLAAQDALARLR--EQSGEEFEDSQDVTEYMQQLL- 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 909 edlvnEKLKTQQMNNDleKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLKKSL--EIKEEKIAALEARLeest 986
Cdd:PRK04863 638 -----ERERELTVERD--ELAARKQALDEEIERLSQPGGSEDPRLNALAERFGGVLLSEIydDVSLEDAPYFSALY---- 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 987 nlnQQLRQ-----ELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSVNKWEKE--NQETTRELLKVKDRLIEV----- 1054
Cdd:PRK04863 707 ---GPARHaivvpDLSDAAEQLAGLEDCPEDLYLIEGDPDSFDDSVFSVEELEKAvvVKIADRQWRYSRFPEVPLfgraa 783
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1055 -ERNNATLQAEKQALKTQLKQL-----ETQNNNLQAQILALQRQTVSLQEQnttlqtQNAKLQVENSTLNSQSTSLMNQN 1128
Cdd:PRK04863 784 rEKRIEQLRAEREELAERYATLsfdvqKLQRLHQAFSRFIGSHLAVAFEAD------PEAELRQLNRRRVELERALADHE 857
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1129 AQLLIQQSALENEKEGV--LKELEDLKSLydsLLKDH--EKLEHLHER--QASEYESLIAKHGSLKSAhknlevehkdLE 1202
Cdd:PRK04863 858 SQEQQQRSQLEQAKEGLsaLNRLLPRLNL---LADETlaDRVEEIREQldEAEEAKRFVQQHGNALAQ----------LE 924
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1203 DRYSQLLKQKVQLEELekvlkteQEKMLQQNEKHETVAAEYKKLRDENDRLAH-----THDQLLKE---NEVLQTDHKNL 1274
Cdd:PRK04863 925 PIVSVLQSDPEQFEQL-------KQDYQQAQQTQRDAKQQAFALTEVVQRRAHfsyedAAEMLAKNsdlNEKLRQRLEQA 997
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1275 KTLLNNSKLGQTQLEAEFSKLREEYQLLDikcTKISNQCELLSQLKG-----------NMEEENRHLLDQIQTLMLQNRT 1343
Cdd:PRK04863 998 EQERTRAREQLRQAQAQLAQYNQVLASLK---SSYDAKRQMLQELKQelqdlgvpadsGAEERARARRDELHARLSANRS 1074
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 1344 lleqnmeskdlfhveQRQYIDK--------LNELRRQKEKLEEKIMDQYKFYEPS 1390
Cdd:PRK04863 1075 ---------------RRNQLEKqltfceaeMDNLTKKLRKLERDYHEMREQVVNA 1114
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
432-1351 |
2.92e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 52.75 E-value: 2.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 432 LEQINRFTDHSEVSHKSLGLEVTEltSSRLLKLEKENQSLLKTVEELRSTMDDsvggnssrivkmeKENQRLNKKIEELE 511
Cdd:TIGR01612 1364 IDEVKEYTKEIEENNKNIKDELDK--SEKLIKKIKDDINLEECKSKIESTLDD-------------KDIDECIKKIKELK 1428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 512 KEIVQEKQslqdnqNLSKDLMKEKEQlekkfetlRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIeKENKI 591
Cdd:TIGR01612 1429 NHILSEES------NIDTYFKNADEN--------NENVLLLFKNIEMADNKSQHILKIKKDNATNDHDFNINEL-KEHID 1493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 592 LHESIKETSSKlNKlefeiKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKensdLDIE 671
Cdd:TIGR01612 1494 KSKGCKDEADK-NA-----KAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKK----FILE 1563
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 672 NRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASfkkS 751
Cdd:TIGR01612 1564 AEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKISSFSID---S 1640
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 752 ERLEVSYQGLDTEN-QRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEElviSSKRLEQ--LEKENKLLEQETSQLE 828
Cdd:TIGR01612 1641 QDTELKENGDNLNSlQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQ---HKKNYEIgiIEKIKEIAIANKEEIE 1717
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 829 KDKKQLEKENKRLRQQAEIKD-------STLEENNVKINHLEKENKSLFKQIAVYKESCVR--LKELEMEN------KEL 893
Cdd:TIGR01612 1718 SIKELIEPTIENLISSFNTNDlegidpnEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKepITYDEIKNtrinaqNEF 1797
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 894 VKRASIDKKTLVTLREDLVNE--------KLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLE-------- 957
Cdd:TIGR01612 1798 LKIIEIEKKSKSYLDDIEAKEfdriinhfKKKLDHVNDKFTKEYSKINEGFDDISKSIENVKNSTDENLLFDilnktkda 1877
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 958 -SKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKK-NYEALKQRQEEERMVQNPPPRKGEENQSVNKWeK 1035
Cdd:TIGR01612 1878 yAGIIGKKYYSYKDEAEKIFINISKLANSINIQIQNNSGIDLFDNiNIAILSSLDSEKEDTLKFIPSPEKEPEIYTKI-R 1956
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1036 ENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQletqNNNLQAQILALQ-RQTVSLQEQNTTLQTQNAKLQVEN 1114
Cdd:TIGR01612 1957 DSYDTLLDIFKKSQDLHKKEQDTLNIIFENQQLYEKIQA----SNELKDTLSDLKyKKEKILNDVKLLLHKFDELNKLSC 2032
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1115 STLNSQSTSLMNQNAQLLIQQSALENEKE--GVLKELEDLKSLYDSLLKDHEKLEHlherqaseyesliakhgslksAHK 1192
Cdd:TIGR01612 2033 DSQNYDTILELSKQDKIKEKIDNYEKEKEkfGIDFDVKAMEEKFDNDIKDIEKFEN---------------------NYK 2091
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1193 NLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENdrLAHTHDQLLkenEVLQTDHK 1272
Cdd:TIGR01612 2092 HSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTEIKIIEDKIIEKNDLIDKLIEMRKEC--LLFSYATLV---ETLKSKVI 2166
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 1273 NLKTLLNNSklgqtqleAEFSKlrEEYQLLDIKCTKISNQCELLsQLKGNMEEENRHLLDQIQTLMLQNRTLLEQNMES 1351
Cdd:TIGR01612 2167 NHSEFITSA--------AKFSK--DFFEFIEDISDSLNDDIDAL-QIKYNLNQTKKHMISILADATKDHNNLIEKEKEA 2234
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
905-1379 |
3.13e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 52.33 E-value: 3.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 905 VTLREDLVNEKLKTQQMNNDLEKLSHEL---EKIGLNKERLLCDE----QSSDDRYKLLEsKLESTLKKSLEIKEEKIAA 977
Cdd:TIGR04523 22 VGYKNIANKQDTEEKQLEKKLKTIKNELknkEKELKNLDKNLNKDeekiNNSNNKIKILE-QQIKDLNDKLKKNKDKINK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 978 LEArleESTNLNQQLRQELKTVKKNYEALKQRQEEERMVqnppprkgeenqsvnkwEKENQETTRELLKVKDRLIEVERN 1057
Cdd:TIGR04523 101 LNS---DLSKINSEIKNDKEQKNKLEVELNKLEKQKKEN-----------------KKNIDKFLTEIKKKEKELEKLNNK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1058 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKlqveNSTLNSQSTSLMNQNAQLLIQQSA 1137
Cdd:TIGR04523 161 YNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQK----NKSLESQISELKKQNNQLKDNIEK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1138 LENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLE---------DRYSQL 1208
Cdd:TIGR04523 237 KQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNnqkeqdwnkELKSEL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1209 LKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKLGQTQL 1288
Cdd:TIGR04523 317 KNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1289 EAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNrTLLEQNMESKDLFHVEQRQYIDKLN- 1367
Cdd:TIGR04523 397 ESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQD-SVKELIIKNLDNTRESLETQLKVLSr 475
|
490
....*....|..
gi 2024492573 1368 ELRRQKEKLEEK 1379
Cdd:TIGR04523 476 SINKIKQNLEQK 487
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
240-666 |
3.53e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.37 E-value: 3.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 240 KHTESKQHLSVELADAKAKIRRLRQEIEEKNEQfldyKQELERVETELRRLQQENKNLLSDARsarvyrdELDILREKAI 319
Cdd:PRK03918 304 EYLDELREIEKRLSRLEEEINGIEERIKELEEK----EERLEELKKKLKELEKRLEELEERHE-------LYEEAKAKKE 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 320 RVDKLESEVGRY-KERLHDM-EFYKARVEELMEDNQVMLETKRMFEDQVKTLQCRSDKLHVVEKENLQLKAKLHEMEMER 397
Cdd:PRK03918 373 ELERLKKRLTGLtPEKLEKElEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKE 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 398 DMDR--KKIEELMEENMALEMAQKQSMDESLHLGWELEQINRFTDHSEVSHKSLGLEvTELTSSRLLKLEKENQSLLKTV 475
Cdd:PRK03918 453 LLEEytAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELE-EKLKKYNLEELEKKAEEYEKLK 531
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 476 EELRSTMDDSVGGNS--SRIVKMEKENQRLNKKIEELEKEI---------------------VQEKQSLQDNQNLSKDLM 532
Cdd:PRK03918 532 EKLIKLKGEIKSLKKelEKLEELKKKLAELEKKLDELEEELaellkeleelgfesveeleerLKELEPFYNEYLELKDAE 611
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 533 KEKEQLEKKFETLRENLERQIKLLEQENERsnqtIASLRQRSQisaEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQ 612
Cdd:PRK03918 612 KELEREEKELKKLEEELDKAFEELAETEKR----LEELRKELE---ELEKKYSEEEYEELREEYLELSRELAGLRAELEE 684
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024492573 613 VRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSITCEKI---EALEKENS 666
Cdd:PRK03918 685 LEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVkkyKALLKERA 741
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-846 |
3.57e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 51.37 E-value: 3.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 657 KIEALEKENSDLDIENRKLKKTLDSLKNlsfQLESLEKENSQLDEENLELRRRIESSKctsikmAQLQLENKELESEKEQ 736
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQ------AEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 737 LKKSLELMKASFKKSERLEV----------------------SYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQ 794
Cdd:COG3883 88 LGERARALYRSGGSVSYLDVllgsesfsdfldrlsalskiadADADLLEELKADKAELEAKKAELEAKLAELEALKAELE 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 795 TLQKNLEELVIS-SKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3883 168 AAKAELEAQQAEqEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| Macoilin |
pfam09726 |
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ... |
463-710 |
4.91e-06 |
|
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.
Pssm-ID: 462859 [Multi-domain] Cd Length: 670 Bit Score: 51.78 E-value: 4.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 463 KLEKENQSLLKTVEELRSTMDDSVGGNSS---RIVKMEKENQRLNKKIEELekeiVQEKQslQDNQNLSkdlmkekeQLE 539
Cdd:pfam09726 406 KLKAELQASRQTEQELRSQISSLTSLERSlksELGQLRQENDLLQTKLHNA----VSAKQ--KDKQTVQ--------QLE 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 540 KKFETLRENLERQIKLLEQENERSNQTIASlrqRSQISAEAQMKEIEKEnkilhESIKetsSKLNKLEFEIKQVRKEMeh 619
Cdd:pfam09726 472 KRLKAEQEARASAEKQLAEEKKRKKEEEAT---AARAVALAAASRGECT-----ESLK---QRKRELESEIKKLTHDI-- 538
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 620 yKEKAERAEELENELHHL------EKENELLqkkIANLSITCEKIEALEKensDLDIENRkLKKTLDS-LKNLSFQLESL 692
Cdd:pfam09726 539 -KLKEEQIRELEIKVQELrkykesEKDTEVL---MSALSAMQDKNQHLEN---SLSAETR-IKLDLFSaLGDAKRQLEIA 610
|
250
....*....|....*...
gi 2024492573 693 EKENSQLDEENLELRRRI 710
Cdd:pfam09726 611 QGQIYQKDQEIKDLKQKI 628
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
544-711 |
5.22e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.92 E-value: 5.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 544 TLRENLERQIKL--LEQENERSNQTIASLRQRSQiSAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYK 621
Cdd:COG1579 1 AMPEDLRALLDLqeLDSELDRLEHRLKELPAELA-ELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 622 EKAERA------EELENELHHLEKENELLQKKIANLSitcEKIEALEKENSDLDIENRKLKKTLDSLKnlsfqlESLEKE 695
Cdd:COG1579 80 EQLGNVrnnkeyEALQKEIESLKRRISDLEDEILELM---ERIEELEEELAELEAELAELEAELEEKK------AELDEE 150
|
170
....*....|....*.
gi 2024492573 696 NSQLDEENLELRRRIE 711
Cdd:COG1579 151 LAELEAELEELEAERE 166
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
579-1251 |
5.66e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 51.36 E-value: 5.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 579 EAQMKEIEKENKILHESIKETSSKLNKLEFEIK-----QVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSI 653
Cdd:pfam10174 2 QAQLRDLQRENELLRRELDIKESKLGSSMNSIKtfwspELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 654 TCEKIEAL------EKENSDLDIENRKLKKTL--DSLKNLSFQLESLEKENSQLDEENLELRRRIESSKCT------SIK 719
Cdd:pfam10174 82 ELRAQRDLnqllqqDFTTSPVDGEDKFSTPELteENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTlgardeSIK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 720 ----MAQLQLENKELESEKEQLKKSL---------------ELMKASFKKSERLEVSYQGLD--TENQRLQKALENSNKK 778
Cdd:pfam10174 162 klleMLQSKGLPKKSGEEDWERTRRIaeaemqlghlevlldQKEKENIHLREELHRRNQLQPdpAKTKALQTVIEMKDTK 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 779 IQQLEGELQDLESENQTLQKNLEelvissKRLEQLEKENKLLEQETSQLEKDKKQLEKenkrLRQQAEIKDSTLEENNVK 858
Cdd:pfam10174 242 ISSLERNIRDLEDEVQMLKTNGL------LHTEDREEEIKQMEVYKSHSKFMKNKIDQ----LKQELSKKESELLALQTK 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 859 INHLEKENKSLFKQIAVYKEScvrlkeleMENKElvKRASIDKKTLVTLR------EDLVNEKLKT-QQMNNDLEKLSHE 931
Cdd:pfam10174 312 LETLTNQNSDCKQHIEVLKES--------LTAKE--QRAAILQTEVDALRlrleekESFLNKKTKQlQDLTEEKSTLAGE 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 932 LekiglnkerllcdeqssddryklleskleSTLKKSLEIKEEKIAALEARLEestNLNQQLRQELKTVKKNYEALKQRQ- 1010
Cdd:pfam10174 382 I-----------------------------RDLKDMLDVKERKINVLQKKIE---NLQEQLRDKDKQLAGLKERVKSLQt 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1011 -----------------EEERMVQNPPPRKgeenqsvnkwEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLK 1073
Cdd:pfam10174 430 dssntdtalttleealsEKERIIERLKEQR----------EREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLI 499
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1074 QLETQNNNLQAQILALQRQTVSLQ-------EQNTTLQTQNAKLQveNSTLNSQSTSLMNQNAQLLIQQSALENEKEGvl 1146
Cdd:pfam10174 500 DLKEHASSLASSGLKKDSKLKSLEiaveqkkEECSKLENQLKKAH--NAEEAVRTNPEINDRIRLLEQEVARYKEESG-- 575
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1147 KELEDLKSLYDsLLKDHEKLEHLHERQASEYESLIAKHGSlksahknlEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQ 1226
Cdd:pfam10174 576 KAQAEVERLLG-ILREVENEKNDKDKKIAELESLTLRQMK--------EQNKKVANIKHGQQEMKKKGAQLLEEARRRED 646
|
730 740
....*....|....*....|....*.
gi 2024492573 1227 EKMLQQNEKH-ETVAAEYKKLRDEND 1251
Cdd:pfam10174 647 NLADNSQQLQlEELMGALEKTRQELD 672
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
589-831 |
6.01e-06 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 51.17 E-value: 6.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 589 NKILHESIKETSSklnklefEIKQVRKEMEHYKEKAERAEELENELHHLEKEN-ELLQKKIANLSITCEKIEALEKE--- 664
Cdd:PHA02562 169 DKLNKDKIRELNQ-------QIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENiARKQNKYDELVEEAKTIKAEIEEltd 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 665 ---NSDLDIENRK--LKKTLDSLKNLSFQLESLEKENSQLDEENlelrrriESSKCTSikmaQLQLENKELESEKEQLK- 738
Cdd:PHA02562 242 ellNLVMDIEDPSaaLNKLNTAAAKIKSKIEQFQKVIKMYEKGG-------VCPTCTQ----QISEGPDRITKIKDKLKe 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 739 --KSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQknlEELVISSKRLEQLEKE 816
Cdd:PHA02562 311 lqHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQ---AEFVDNAEELAKLQDE 387
|
250
....*....|....*
gi 2024492573 817 NKLLEQETSQLEKDK 831
Cdd:PHA02562 388 LDKIVKTKSELVKEK 402
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
455-649 |
6.35e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 6.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 455 ELTSSRLLKLEKENQSLLKTVEELRSTMDDSvggnSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLM-- 532
Cdd:COG4942 37 AELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLra 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 533 ----------------KEKEQLEKKFETLR---ENLERQIKLLEQENERSNQTIASLRQRSQiSAEAQMKEIEKENKILH 593
Cdd:COG4942 113 lyrlgrqpplalllspEDFLDAVRRLQYLKylaPARREQAEELRADLAELAALRAELEAERA-ELEALLAELEEERAALE 191
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 594 ESIKETSSKLNKLEFEIKQVRKEMEhykEKAERAEELENELHHLEKENELLQKKIA 649
Cdd:COG4942 192 ALKAERQKLLARLEKELAELAAELA---ELQQEAEELEALIARLEAEAAAAAERTP 244
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
265-831 |
6.75e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.51 E-value: 6.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 265 EIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDELDILREKAIRVDKLESevgrykeRLHDMEFYKAR 344
Cdd:TIGR00618 356 HIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTS-------AFRDLQGQLAH 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 345 VEELMEDNQVMLETKRMFEDqvKTLQCrsdklhvvekenlQLKAKLHEMEMERDMDRKKIEELMEENMALEMAQKQSMDE 424
Cdd:TIGR00618 429 AKKQQELQQRYAELCAAAIT--CTAQC-------------EKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVL 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 425 SLHLGWELEQINRFTDHSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSvggnSSRIVKMEKENQRLN 504
Cdd:TIGR00618 494 ARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSE----RKQRASLKEQMQEIQ 569
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 505 KKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLREnlERQIKLLEQENERSNQTIASLRQrsQISAEAQMKE 584
Cdd:TIGR00618 570 QSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC--EQHALLRKLQPEQDLQDVRLHLQ--QCSQELALKL 645
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 585 IEKENKILH-----ESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSITCEKIE 659
Cdd:TIGR00618 646 TALHALQLTltqerVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIEN 725
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 660 ALEKENSDLDIENRKLKKTLDSLKNLS-FQLESLEKENSQLDEENL-ELRRRIESSKCtsikMAQLQLENKELESEKEQL 737
Cdd:TIGR00618 726 ASSSLGSDLAAREDALNQSLKELMHQArTVLKARTEAHFNNNEEVTaALQTGAELSHL----AAEIQFFNRLREEDTHLL 801
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 738 KKSLELMKASFKKSER-LEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESEnqtlQKNLEELVISSKRLEQLEKE 816
Cdd:TIGR00618 802 KTLEAEIGQEIPSDEDiLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEEC----SKQLAQLTQEQAKIIQLSDK 877
|
570
....*....|....*
gi 2024492573 817 NKLLEQETSQLEKDK 831
Cdd:TIGR00618 878 LNGINQIKIQFDGDA 892
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
571-846 |
6.82e-06 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 51.49 E-value: 6.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 571 RQRSQISAE-AQMKEIEKENKILHESIKETSSKLNKLefeikqvRKEMEHYKEK--AERAEELENELHHLEKENELLQKK 647
Cdd:COG3096 843 QRRSELERElAQHRAQEQQLRQQLDQLKEQLQLLNKL-------LPQANLLADEtlADRLEELREELDAAQEAQAFIQQH 915
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 648 ianlsitCEKIEALEKEnsdldienrklkktLDSLKNLSFQLESLEKENSQLDEENLELRRRIES--------SKCTSIK 719
Cdd:COG3096 916 -------GKALAQLEPL--------------VAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFAlsevvqrrPHFSYED 974
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 720 MAQLQLENKELEsekEQLKKSLELMKASFKKS-ERLEVSYQGLDTENQRLQK---ALENSNKKIQQLEGELQDL------ 789
Cdd:COG3096 975 AVGLLGENSDLN---EKLRARLEQAEEARREArEQLRQAQAQYSQYNQVLASlksSRDAKQQTLQELEQELEELgvqada 1051
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 790 ESENQTLQKNLE---ELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3096 1052 EAEERARIRRDElheELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
632-1457 |
8.16e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.30 E-value: 8.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 632 NELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSF-QLESLEKENSQLDEENLELRRRI 710
Cdd:PTZ00121 1021 NQNFNIEKIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYkDFDFDAKEDNRADEATEEAFGKA 1100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 711 ESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKAsfKKSERLEVSYQGLDTENQRLQKALENSNK-KIQQLEGELQDL 789
Cdd:PTZ00121 1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKA--EDARKAEEARKAEDAKRVEIARKAEDARKaEEARKAEDAKKA 1178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 790 ESENQTLQ-KNLEEL-----VISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLE 863
Cdd:PTZ00121 1179 EAARKAEEvRKAEELrkaedARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFE 1258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 864 KENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKiglnkerll 943
Cdd:PTZ00121 1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK--------- 1329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 944 cdeqssddrykllesKLESTLKKSleikEEKIAALEARLEEStnlnQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRK 1023
Cdd:PTZ00121 1330 ---------------KADAAKKKA----EEAKKAAEAAKAEA----EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK 1386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1024 GEENQSVNKWEKENQETTRELLKVKDRlievernnatlQAEKQALKTQLKQLETQNNNLQAQILAlqrqtvslqEQNTTL 1103
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEEDKKKADELKKA-----------AAAKKKADEAKKKAEEKKKADEAKKKA---------EEAKKA 1446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1104 QTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKlehlhERQASEYesliak 1183
Cdd:PTZ00121 1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA-----KKKADEA------ 1515
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1184 hgslksahKNLEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRlahthDQLLKE 1263
Cdd:PTZ00121 1516 --------KKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK-----NMALRK 1582
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1264 NEVLQTDHKNLKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENRHlldqiqtlmlqnrt 1343
Cdd:PTZ00121 1583 AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK-------------- 1648
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1344 lLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYEPSPPRRRgnwitlKMRKLMKSKKDVNRERQKSASL 1423
Cdd:PTZ00121 1649 -AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE------EAKKAEELKKKEAEEKKKAEEL 1721
|
810 820 830
....*....|....*....|....*....|....
gi 2024492573 1424 TPTRSESSEGFLQLPHQDSQDSSSVGSNSLEDGQ 1457
Cdd:PTZ00121 1722 KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE 1755
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
775-1092 |
8.24e-06 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 49.95 E-value: 8.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 775 SNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEqleKENKLLEQETSQLEKDKKQLEKENKRLRQQAeikdSTLEE 854
Cdd:pfam09728 2 AARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQ---KDLKKLKKKQDQLQKEKDQLQSELSKAILAK----SKLEK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 855 nnvKINHLEKENKSLfkqiavYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDL-EKLSHELE 933
Cdd:pfam09728 75 ---LCRELQKQNKKL------KEESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELrEKLKSLIE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 934 KIGLNKERLLCDEQSSDDRYKLLESKLESTL----KKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQ- 1008
Cdd:pfam09728 146 QYELRELHFEKLLKTKELEVQLAEAKLQQATeeeeKKAQEKEVAKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDt 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1009 -----------RQEEERMvqnppprkgeeNQSVNKWEKENQETTRELLKVKDRLIEvernnatLQAEKQALKTQLKQLET 1077
Cdd:pfam09728 226 lnksnevfttfKKEMEKM-----------SKKIKKLEKENLTWKRKWEKSNKALLE-------MAEERQKLKEELEKLQK 287
|
330
....*....|....*
gi 2024492573 1078 QNNNLQAQILALQRQ 1092
Cdd:pfam09728 288 KLEKLENLCRALQAE 302
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
718-873 |
8.81e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.15 E-value: 8.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 718 IKMAQLQLENKELESEKEQLKKSLElmkasfkkseRLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQ 797
Cdd:COG1579 10 LDLQELDSELDRLEHRLKELPAELA----------ELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYE 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 798 KNLEElVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQI 873
Cdd:COG1579 80 EQLGN-VRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAEL 154
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
739-897 |
9.27e-06 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 50.63 E-value: 9.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 739 KSLE--LMKASFKKSERLEVSYQGLDTENQRLQKALEnsnKKIQQLEGELQDLESENQTLQKNLEELvisSKRLEQLEKE 816
Cdd:COG2433 376 LSIEeaLEELIEKELPEEEPEAEREKEHEERELTEEE---EEIRRLEEQVERLEAEVEELEAELEEK---DERIERLERE 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 817 NKLL----------EQETSQLEKDKKQLEKENKRLRqqaeikdSTLEENNVKINHLEKENKSLFkqiavyKESCVRLKEL 886
Cdd:COG2433 450 LSEArseerreirkDREISRLDREIERLERELEEER-------ERIEELKRKLERLKELWKLEH------SGELVPVKVV 516
|
170
....*....|.
gi 2024492573 887 EMENKELVKRA 897
Cdd:COG2433 517 EKFTKEAIRRL 527
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
243-817 |
1.14e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.61 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 243 ESKQHLSVELADAKAKIRRLRQEIE---EKNEQFLD-----YKQELER---VETELRRLQQENKNLLSDARSARVYRDel 311
Cdd:pfam12128 301 EKRDELNGELSAADAAVAKDRSELEaleDQHGAFLDadietAAADQEQlpsWQSELENLEERLKALTGKHQDVTAKYN-- 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 312 dilREKAIRVDKLESEVGRYKERLHDMEFYKARVEELMEDNQVMLET----------------KRMFEDQVKTLQCRSDK 375
Cdd:pfam12128 379 ---RRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESelreqleagklefneeEYRLKSRLGELKLRLNQ 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 376 LHVVEKENLQLKAK---LHEMEMERDMDRKKIEELMEENMALEMAQKQSMDEslhlgweLEQINRFTDHSEVSHKSLGLE 452
Cdd:pfam12128 456 ATATPELLLQLENFderIERAREEQEAANAEVERLQSELRQARKRRDQASEA-------LRQASRRLEERQSALDELELQ 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 453 VTELTSSRLLKLEKE----NQSLLKTVEE---LRSTMDDSV------GGNSSRIVKMEKENQRLNKKI---EELEKEIVQ 516
Cdd:pfam12128 529 LFPQAGTLLHFLRKEapdwEQSIGKVISPellHRTDLDPEVwdgsvgGELNLYGVKLDLKRIDVPEWAaseEELRERLDK 608
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 517 EKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQenersnqtiASLRQRsQISAEAQmKEIEKENKILHESI 596
Cdd:pfam12128 609 AEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN---------ARLDLR-RLFDEKQ-SEKDKKNKALAERK 677
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 597 KETSSKLNKLEFEIKQVRKEMEHYKEkAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEkensdldienrklk 676
Cdd:pfam12128 678 DSANERLNSLEAQLKQLDKKHQAWLE-EQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARR-------------- 742
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 677 ktldslknlsfqlESLEKENSQLDEENlelRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLElmkasfkKSERLEV 756
Cdd:pfam12128 743 -------------SGAKAELKALETWY---KRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQ-------EVLRYFD 799
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 757 SYQG-LDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKEN 817
Cdd:pfam12128 800 WYQEtWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSEN 861
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
507-775 |
1.17e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 50.31 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 507 IEELEKEIVQEKQSlqdnqnlskDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQISAEaqmkEIE 586
Cdd:PRK05771 33 IEDLKEELSNERLR---------KLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELE----KIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 587 KEnkilhesIKETSSKLNKLEFEIKQVRKEMehykekaeraEELENeLHHLEKENELLQKKiANLSITCEKIEALEKENS 666
Cdd:PRK05771 100 KE-------IKELEEEISELENEIKELEQEI----------ERLEP-WGNFDLDLSLLLGF-KYVSVFVGTVPEDKLEEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 667 DLDIENRKLkKTLDSLKNLSF--------QLESLEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLK 738
Cdd:PRK05771 161 KLESDVENV-EYISTDKGYVYvvvvvlkeLSDEVEEELKKLGFERLELEEEGTPSELIREIKEELEEIEKERESLLEELK 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 739 KSLE----LMKASFKK----SERLEVSYQGLDTEN-------------QRLQKALENS 775
Cdd:PRK05771 240 ELAKkyleELLALYEYleieLERAEALSKFLKTDKtfaiegwvpedrvKKLKELIDKA 297
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
492-844 |
1.22e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 50.68 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 492 RIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEK------EQLEKKFETLRENLER-QIKLLEQENERSN 564
Cdd:PRK11281 74 KIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETlstlslRQLESRLAQTLDQLQNaQNDLAEYNSQLVS 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 565 QTIASLRQRSQISA-EAQMKEIEKENKILHESIKETS-SKLNKLEFE-------IKQVRKEMEHYKE-----KAERaEEL 630
Cdd:PRK11281 154 LQTQPERAQAALYAnSQRLQQIRNLLKGGKVGGKALRpSQRVLLQAEqallnaqNDLQRKSLEGNTQlqdllQKQR-DYL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 631 ENELHHLEKENELLQKKI--ANLSITCEKI-EALEKENSDLDIENRKLKKTLDSLKNLS-FQLESLEKENsQLDEENLEL 706
Cdd:PRK11281 233 TARIQRLEHQLQLLQEAInsKRLTLSEKTVqEAQSQDEAARIQANPLVAQELEINLQLSqRLLKATEKLN-TLTQQNLRV 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 707 RRRIESskctsikmaqLQLENKELESEKEQLKKSLELMKASFKKSERL--EVSYQGLDTE--NQRLQK--------ALEN 774
Cdd:PRK11281 312 KNWLDR----------LTQSERNIKEQISVLKGSLLLSRILYQQQQALpsADLIEGLADRiaDLRLEQfeinqqrdALFQ 381
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 775 SNKKIQQLEgelQDLESE-NQTLQKNLEELVIS-SKRLEQLEKE-NKLLEQETSqLEKDKKQLEKENKRLRQQ 844
Cdd:PRK11281 382 PDAYIDKLE---AGHKSEvTDEVRDALLQLLDErRELLDQLNKQlNNQLNLAIN-LQLNQQQLLSVSDSLQST 450
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
628-1015 |
1.61e-05 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 49.68 E-value: 1.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 628 EELENELHHLEKENELLQKKIANLSITCEKIEALEKEnSDLDIENRKLkktldSLKNLSFQLESLEKENSQLDEENLELR 707
Cdd:pfam19220 65 GKLRRELAGLTRRLSAAEGELEELVARLAKLEAALRE-AEAAKEELRI-----ELRDKTAQAEALERQLAAETEQNRALE 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 708 rriesskctsikmaqlqLENKELESEKEQLKKSL-ELMKASFKKSERLEVsyqgLDTENQRLQKALENSNKKIQQLEGEL 786
Cdd:pfam19220 139 -----------------EENKALREEAQAAEKALqRAEGELATARERLAL----LEQENRRLQALSEEQAAELAELTRRL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 787 QDLESENQTLQKNLEELvisskrleqlekENKLLEqETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKEN 866
Cdd:pfam19220 198 AELETQLDATRARLRAL------------EGQLAA-EQAERERAEAQLEEAVEAHRAERASLRMKLEALTARAAATEQLL 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 867 KSLFKQIAVYKEScvrLKELEMENKElvkrASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEkiglnkERllcde 946
Cdd:pfam19220 265 AEARNQLRDRDEA---IRAAERRLKE----ASIERDTLERRLAGLEADLERRTQQFQEMQRARAELE------ER----- 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 947 qsSDDRYKLLESKlestlKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKknyEALKQRQEEERM 1015
Cdd:pfam19220 327 --AEMLTKALAAK-----DAALERAEERIASLSDRIAELTKRFEVERAALEQAN---RRLKEELQRERA 385
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
267-695 |
1.61e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 1.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 267 EEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSARVYRDELDILREKAIRVDKLESEVGRYKERLHDMEFYKARVE 346
Cdd:COG4717 53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQ 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 347 ELMEDNQVMLETK---RMFEDQVKTLQCRSDKLHVVEKENLQLKAKLHEMEMERDMD--------RKKIEELMEENMALE 415
Cdd:COG4717 133 ELEALEAELAELPerlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLAteeelqdlAEELEELQQRLAELE 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 416 MAQKQSMDESLHLGWELEQINRFTDHSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVK 495
Cdd:COG4717 213 EELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLL 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 496 MEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQ--TIASLRQR 573
Cdd:COG4717 293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEElqLEELEQEI 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 574 SQISAEAQMKEIEKENKIL--HESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERaEELENELHHLEKENELLQKKIANL 651
Cdd:COG4717 373 AALLAEAGVEDEEELRAALeqAEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEEL 451
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2024492573 652 SitcEKIEALEKENSDLDiENRKLKKTLDSLKNLSFQLESLEKE 695
Cdd:COG4717 452 R---EELAELEAELEQLE-EDGELAELLQELEELKAELRELAEE 491
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
260-791 |
1.81e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.17 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 260 RRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSArvyRDELDILREKAIRVDKLESEVGRYKERLHDmE 339
Cdd:pfam01576 548 KRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQ---RQLVSNLEKKQKKFDQMLAEEKAISARYAE-E 623
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 340 FYKARVEELMEDNQVMLETKRMFEDQvktlqcrsDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEmAQK 419
Cdd:pfam01576 624 RDRAEAEAREKETRALSLARALEEAL--------EAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALE-QQV 694
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 420 QSMDESL-HLGWELEQINRFTDHSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIV---K 495
Cdd:pfam01576 695 EEMKTQLeELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAakkK 774
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 496 MEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQL----EKKFETLRENlERQIKLLEQENERSNQTIAslr 571
Cdd:pfam01576 775 LELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEArasrDEILAQSKES-EKKLKNLEAELLQLQEDLA--- 850
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 572 qrsqiSAEAQMKEIEKENKILHESIKETSSKLN-------KLEFEIKQVRKEMEhykEKAERAEELENELHHLEKENELL 644
Cdd:pfam01576 851 -----ASERARRQAQQERDELADEIASGASGKSalqdekrRLEARIAQLEEELE---EEQSNTELLNDRLRKSTLQVEQL 922
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 645 QKKIANLSITCEKIEA----LEKENSDLDIENRKLKKTLDSLKNLSfqLESLEKENSQLDEE-NLELRRRIESSKCTSIK 719
Cdd:pfam01576 923 TTELAAERSTSQKSESarqqLERQNKELKAKLQEMEGTVKSKFKSS--IAALEAKIAQLEEQlEQESRERQAANKLVRRT 1000
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 720 -------MAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLES 791
Cdd:pfam01576 1001 ekklkevLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKS 1079
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
639-878 |
1.88e-05 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 48.80 E-value: 1.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 639 KENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNlsfQLESLEKENSQLDEENlelrRRIESSKCTSI 718
Cdd:pfam09728 1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKK---KQDQLQKEKDQLQSEL----SKAILAKSKLE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 719 KMAQ-LQLENKELESEKEQLKKSLElmkasfkkSERLEVSyqgldtenQRLQKALENSNKKIQQLEGELQDLESENQTLQ 797
Cdd:pfam09728 74 KLCReLQKQNKKLKEESKKLAKEEE--------EKRKELS--------EKFQSTLKDIQDKMEEKSEKNNKLREENEELR 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 798 KNLEELV-ISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKinHLEKENKSLFKQIAVY 876
Cdd:pfam09728 138 EKLKSLIeQYELRELHFEKLLKTKELEVQLAEAKLQQATEEEEKKAQEKEVAKARELKAQVQ--TLSETEKELREQLNLY 215
|
..
gi 2024492573 877 KE 878
Cdd:pfam09728 216 VE 217
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
964-1302 |
2.13e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 49.97 E-value: 2.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 964 LKKSLEIKEEKIAALEaRLEESTNLNQQLRQELKTVKKNYEALKQRQEEERmvQNPPPRKGEENQSVNKWEKENQETTRE 1043
Cdd:TIGR00618 158 LKAKSKEKKELLMNLF-PLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLT--LCTPCMPDTYHERKQVLEKELKHLREA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1044 LLKVKDRLIEVERNNaTLQAEKQALKTQLKQLETQNNNLQAQILAL---------QRQTVSLQEQNTTLQTQNAKLQVEN 1114
Cdd:TIGR00618 235 LQQTQQSHAYLTQKR-EAQEEQLKKQQLLKQLRARIEELRAQEAVLeetqerinrARKAAPLAAHIKAVTQIEQQAQRIH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1115 STLNSQstslMNQNAQLLIQQSALENEKEgvlkELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHgslksahknl 1194
Cdd:TIGR00618 314 TELQSK----MRSRAKLLMKRAAHVKQQS----SIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQH---------- 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1195 evehkDLEDRYSQLLKQKVQLEELEKVLKTEQEKMlqQNEKHeTVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNL 1274
Cdd:TIGR00618 376 -----TLTQHIHTLQQQKTTLTQKLQSLCKELDIL--QREQA-TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI 447
|
330 340
....*....|....*....|....*...
gi 2024492573 1275 KTLLNNSKLGQTQLEAEFSKLREEYQLL 1302
Cdd:TIGR00618 448 TCTAQCEKLEKIHLQESAQSLKEREQQL 475
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
791-1014 |
2.17e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 2.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 791 SENQTLQKNLEELvisSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLF 870
Cdd:COG4942 20 DAAAEAEAELEQL---QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 871 KQIAVYKEscvrlkELEMENKELVKRASIDKKTLVTLRED-------LVNEKLKTQQMNNDLEKLSHELEKIGLNKERLL 943
Cdd:COG4942 97 AELEAQKE------ELAELLRALYRLGRQPPLALLLSPEDfldavrrLQYLKYLAPARREQAEELRADLAELAALRAELE 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 944 CDEQSSDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEER 1014
Cdd:COG4942 171 AERAELEALLAELEEERAA-LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
529-822 |
2.21e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 48.37 E-value: 2.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 529 KDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQisaeaQMKEIEKENKILHESIKETSSKLNKLEF 608
Cdd:COG1340 11 EELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELRE-----EAQELREKRDELNEKVKELKEERDELNE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 609 EIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIanlsitcekiealekENSDLDIEnrKLKKTLDSLKNLSFQ 688
Cdd:COG1340 86 KLNELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQ---------------QTEVLSPE--EEKELVEKIKELEKE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 689 LESLEKENsQLDEENLELRRRIESSKctsikmAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRL 768
Cdd:COG1340 149 LEKAKKAL-EKNEKLKELRAELKELR------KEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEA 221
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 2024492573 769 QKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQ 822
Cdd:COG1340 222 QEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEELEEKAEEIFEK 275
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
706-906 |
2.61e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.01 E-value: 2.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 706 LRRRIESSKCTSIK-MAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALEnsnKKIQQLEG 784
Cdd:PRK12704 24 VRKKIAEAKIKEAEeEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLL---QKEENLDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 785 ELQDLESENQTLQKNLEELVISSKRLEQLEKE-NKLLEQETSQLEKdKKQLEKEnkrlrqqaEIKDSTLEEnnvkinhLE 863
Cdd:PRK12704 101 KLELLEKREEELEKKEKELEQKQQELEKKEEElEELIEEQLQELER-ISGLTAE--------EAKEILLEK-------VE 164
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2024492573 864 KENKslfKQIAVYkescvrLKELEMENKELVKRASidKKTLVT 906
Cdd:PRK12704 165 EEAR---HEAAVL------IKEIEEEAKEEADKKA--KEILAQ 196
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
948-1141 |
2.61e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.67 E-value: 2.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 948 SSDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQE--EERMVQNppprkge 1025
Cdd:COG3883 13 FADPQIQAKQKELSE-LQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAeaEAEIEER------- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1026 eNQSVNKWEKENQETTRE------LLKVK------DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1093
Cdd:COG3883 85 -REELGERARALYRSGGSvsyldvLLGSEsfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2024492573 1094 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENE 1141
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
638-940 |
2.76e-05 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 49.45 E-value: 2.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 638 EKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQL-----ESLEKENSQLDEENLELRRRIES 712
Cdd:PRK00448 5 EKFKKLLDQINIPDDLQSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDfklfkEKLKQSFSHIADIKVTFSIEVEN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 713 SKCTSikmaqlQLENKELESEKEQLKKSLELMKASFKKSE------RLEVSYQGlDTENQRL-QKALENSNKKIQQLEGE 785
Cdd:PRK00448 85 ITFTE------ELLLDYWNEIIEKAKKNSPLFKSLLKKQKvevegnKLIIKVNN-EIERDHLkKKHLPKLIKQYEKFGFG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 786 LQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAE----------IKDSTLEEN 855
Cdd:PRK00448 158 ILKIDFEIDDSKEELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDPKEGPVQIGkkidkeeitpMKEINEEER 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 856 NVKIN----HLE-KENKS-----LFKqIAVYKEScVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKL-KTQQMN-N 923
Cdd:PRK00448 238 RVVVEgyvfKVEiKELKSgrhilTFK-ITDYTSS-IIVKKFSRDKEDLKKFDEIKKGDWVKVRGSVQNDTFtRDLVMNaQ 315
|
330
....*....|....*..
gi 2024492573 924 DLEKLSHELEKIGLNKE 940
Cdd:PRK00448 316 DINEIKHPERKDTAEEE 332
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
719-896 |
3.21e-05 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 46.46 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 719 KMAQLQLENKELESEKEQLKKSLELMKASfkKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQK 798
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLS--KASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 799 NLEElviSSKRLEQLEKENklleqetSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKenkslfkqiavyke 878
Cdd:pfam08614 93 KLRE---DERRLAALEAER-------AQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEE-------------- 148
|
170
....*....|....*...
gi 2024492573 879 scvRLKELEMENKELVKR 896
Cdd:pfam08614 149 ---KLRKLEKENRELVER 163
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
699-1012 |
3.41e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 49.13 E-value: 3.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 699 LDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSE-RLEVSYQGLDTENQRLQKALENSNK 777
Cdd:PLN02939 42 FSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDdHNRASMQRDEAIAAIDNEQQTNSKD 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 778 KIQQLEGELQDLESENQTLQKNLeeLVISSKRL-------------EQLEKENKLLE--------------QETSQLEKD 830
Cdd:PLN02939 122 GEQLSDFQLEDLVGMIQNAEKNI--LLLNQARLqaledlekiltekEALQGKINILEmrlsetdariklaaQEKIHVEIL 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 831 KKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLRED 910
Cdd:PLN02939 200 EEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESK 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 911 LVNE-----KLKTQQMN---NDLEKLSHELEKIGLNKER-LLCDEQSSDDRYKLleSKLESTLKKS---------LEIKE 972
Cdd:PLN02939 280 FIVAqedvsKLSPLQYDcwwEKVENLQDLLDRATNQVEKaALVLDQNQDLRDKV--DKLEASLKEAnvskfssykVELLQ 357
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2024492573 973 EKIAALEARLEESTN-LNQQLRQELKTVKKNYEALKQRQEE 1012
Cdd:PLN02939 358 QKLKLLEERLQASDHeIHSYIQLYQESIKEFQDTLSKLKEE 398
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
945-1113 |
3.52e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.86 E-value: 3.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 945 DEQSSDDRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNLNQQLRQ--ELKTVKKNYEALKQRQEEERMvqnpppR 1022
Cdd:COG3206 213 EAKLLLQQLSELESQL-AEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSA------R 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1023 KGEENQSVNKWEKENQETTRELLK-VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL---QAQILALQRQTVSLQE 1098
Cdd:COG3206 286 YTPNHPDVIALRAQIAALRAQLQQeAQRILASLEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARE 365
|
170
....*....|....*
gi 2024492573 1099 QNTTLQTQNAKLQVE 1113
Cdd:COG3206 366 LYESLLQRLEEARLA 380
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
764-1017 |
3.79e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.77 E-value: 3.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 764 ENQRLQKALENSNK------KIQQLEGELQDLESENQTLQKN-LEELV-ISSKRLEQLEKENKLLEQETSQLEKDKKQLE 835
Cdd:PRK05771 41 SNERLRKLRSLLTKlsealdKLRSYLPKLNPLREEKKKVSVKsLEELIkDVEEELEKIEKEIKELEEEISELENEIKELE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 836 KENKRLRQqaeIKDSTLEEnnvkINHLEKENKSLFK-QIAVYKEScvRLKELEMENKELVKRASIDKKTLVtlredLVNE 914
Cdd:PRK05771 121 QEIERLEP---WGNFDLDL----SLLLGFKYVSVFVgTVPEDKLE--ELKLESDVENVEYISTDKGYVYVV-----VVVL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 915 KlktqqmnNDLEKLSHELEKIGLNKERLLcDEQSSDDRYKLLESKLEStLKKsleIKEEKIAALEARLEESTNLNQQLRQ 994
Cdd:PRK05771 187 K-------ELSDEVEEELKKLGFERLELE-EEGTPSELIREIKEELEE-IEK---ERESLLEELKELAKKYLEELLALYE 254
|
250 260
....*....|....*....|...
gi 2024492573 995 ELKTVKKNYEALKQRQEEERMVQ 1017
Cdd:PRK05771 255 YLEIELERAEALSKFLKTDKTFA 277
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
452-625 |
3.89e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.77 E-value: 3.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 452 EVTELTSsRLLKLEKENQSLLKTVEELRS----TMDDSV---GGNSSRIVKmekenqRLNKKIEELEKEIVQEKQSLQDN 524
Cdd:PRK05771 101 EIKELEE-EISELENEIKELEQEIERLEPwgnfDLDLSLllgFKYVSVFVG------TVPEDKLEELKLESDVENVEYIS 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 525 QNLSKD---LMKEKEQLEKKFETLRENLERQIKLLEQENerSNQTIASLRQRsqisaeaqMKEIEKENKILHESIKEtss 601
Cdd:PRK05771 174 TDKGYVyvvVVVLKELSDEVEEELKKLGFERLELEEEGT--PSELIREIKEE--------LEEIEKERESLLEELKE--- 240
|
170 180
....*....|....*....|....
gi 2024492573 602 KLNKLEFEIKQVRKEMEHYKEKAE 625
Cdd:PRK05771 241 LAKKYLEELLALYEYLEIELERAE 264
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
924-1146 |
3.95e-05 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 48.90 E-value: 3.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 924 DLEKLSHELEKIGLNKE--------------RLLCDEQSSDDRYKLLES------KLESTLKKSLEIKEEKIAALEARLE 983
Cdd:PRK10929 24 DEKQITQELEQAKAAKTpaqaeivealqsalNWLEERKGSLERAKQYQQvidnfpKLSAELRQQLNNERDEPRSVPPNMS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 984 eSTNLNQQLRQelktvkknyeALKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRL--------IEVE 1055
Cdd:PRK10929 104 -TDALEQEILQ----------VSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERRLqtlgtpntPLAQ 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1056 RNNATLQAEKQALKTQLKQLETqnnnlqAQILALQRQTVS------LQEQNTTLqtqNAKLQVENSTLNSQStslmNQNA 1129
Cdd:PRK10929 173 AQLTALQAESAALKALVDELEL------AQLSANNRQELArlrselAKKRSQQL---DAYLQALRNQLNSQR----QREA 239
|
250
....*....|....*..
gi 2024492573 1130 QLLIQQSALENEKEGVL 1146
Cdd:PRK10929 240 ERALESTELLAEQSGDL 256
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
495-590 |
4.04e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 48.62 E-value: 4.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 495 KMEKENQRLNKKIEELEKEIVQEKQSL-----------QDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQ----- 558
Cdd:PRK12704 72 EFEKELRERRNELQKLEKRLLQKEENLdrklellekreEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisglt 151
|
90 100 110
....*....|....*....|....*....|..
gi 2024492573 559 ENERSNQTIASLRQRSQISAEAQMKEIEKENK 590
Cdd:PRK12704 152 AEEAKEILLEKVEEEARHEAAVLIKEIEEEAK 183
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
447-1308 |
4.06e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.80 E-value: 4.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 447 KSLGLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVggnssriVKMEKENQRLNKKIEEL------EKEIVQEKQS 520
Cdd:PRK04863 260 KHLITESTNYVAADYMRHANERRVHLEEALELRRELYTSR-------RQLAAEQYRLVEMARELaelneaESDLEQDYQA 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 521 LQDNQNLSKDLMKEKEQLEKKFETLrenLERQIKLLEQenersnqtiaslrqrSQISAEAQMKEIEKENK--ILHESIKE 598
Cdd:PRK04863 333 ASDHLNLVQTALRQQEKIERYQADL---EELEERLEEQ---------------NEVVEEADEQQEENEARaeAAEEEVDE 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 599 TSSKLNKLE--FEIKQVRK-EMEHYKEKAERAEELeNELHHLEKEN--ELLQKKIANLSITCEKIEALEKENSDLDIENR 673
Cdd:PRK04863 395 LKSQLADYQqaLDVQQTRAiQYQQAVQALERAKQL-CGLPDLTADNaeDWLEEFQAKEQEATEELLSLEQKLSVAQAAHS 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 674 KLKKTLDSLKNLSFQLESlekenSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQlKKSLELMKASFkkser 753
Cdd:PRK04863 474 QFEQAYQLVRKIAGEVSR-----SEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQ-QQRAERLLAEF----- 542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 754 levsyqgldteNQRLQKALENsnkkIQQLEGELQDLESENQTLQKNLEELVissKRLEQLEKENKLLEQETSQLEKDKKQ 833
Cdd:PRK04863 543 -----------CKRLGKNLDD----EDELEQLQEELEARLESLSESVSEAR---ERRMALRQQLEQLQARIQRLAARAPA 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 834 LEKENKRLRQQAEIKDSTLEEN----NVKINHLEKEnKSLfkqIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLRE 909
Cdd:PRK04863 605 WLAAQDALARLREQSGEEFEDSqdvtEYMQQLLERE-REL---TVERDELAARKQALDEEIERLSQPGGSEDPRLNALAE 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 910 D----LVNE--------------KLKTQQMN----NDLEKLSHELEKIGLNKERLLCDEQSSDdryKLLESKLEST-LKK 966
Cdd:PRK04863 681 RfggvLLSEiyddvsledapyfsALYGPARHaivvPDLSDAAEQLAGLEDCPEDLYLIEGDPD---SFDDSVFSVEeLEK 757
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 967 SLEIKEEKI---------------AALEARLEestnlnqQLRQELKTVKKNYEALK-QRQEEERMVQNPPPRKGEENQSV 1030
Cdd:PRK04863 758 AVVVKIADRqwrysrfpevplfgrAAREKRIE-------QLRAEREELAERYATLSfDVQKLQRLHQAFSRFIGSHLAVA 830
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1031 NKWEKEnqettRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA---QILALQRQTvsLQEQNTTLQTQN 1107
Cdd:PRK04863 831 FEADPE-----AELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRllpRLNLLADET--LADRVEEIREQL 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1108 AKLQVENSTLNSQSTSLmnqnAQLLIQQSALENEKEgvlkELEDLKSLYDSLLKDHEKLehlhERQASEYESLIAK--HG 1185
Cdd:PRK04863 904 DEAEEAKRFVQQHGNAL----AQLEPIVSVLQSDPE----QFEQLKQDYQQAQQTQRDA----KQQAFALTEVVQRraHF 971
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1186 SLKSAHKNLEvEHKDLEDRYSQLLKQK-VQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQL---- 1260
Cdd:PRK04863 972 SYEDAAEMLA-KNSDLNEKLRQRLEQAeQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgvpa 1050
|
890 900 910 920
....*....|....*....|....*....|....*....|....*....
gi 2024492573 1261 -LKENEVLQTDHKNLKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKCTK 1308
Cdd:PRK04863 1051 dSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRK 1099
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
956-1123 |
4.52e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 4.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 956 LESKLEStLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKT----VKKNYEALKQR----QEEERMV---------QN 1018
Cdd:COG3883 35 AQAELDA-LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEaeaeIEERREELGERaralYRSGGSVsyldvllgsES 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1019 PpprkGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1098
Cdd:COG3883 114 F----SDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSA 189
|
170 180
....*....|....*....|....*
gi 2024492573 1099 QNTTLQTQNAKLQVENSTLNSQSTS 1123
Cdd:COG3883 190 EEAAAEAQLAELEAELAAAEAAAAA 214
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
974-1386 |
4.75e-05 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 48.29 E-value: 4.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 974 KIAALEARLEESTNLNqqLRQELKTVKKnyeaLKQrqeeermvqnppprKGEENQSVNKWEKENQE-TTRELLKVKDRLI 1052
Cdd:PRK04778 30 RIDELEERKQELENLP--VNDELEKVKK----LNL--------------TGQSEEKFEEWRQKWDEiVTNSLPDIEEQLF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1053 EVERNNAT--LQAEKQALKT---QLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQvenSTLNSQSTSLMNQ 1127
Cdd:PRK04778 90 EAEELNDKfrFRKAKHEINEiesLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELR---KSLLANRFSFGPA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1128 NAQLliqQSALENEKEGvLKELEDLKS------LYDSLLKDHEKLEHLhERQASEYESLIAKhgslksAHKNLEVEHKDL 1201
Cdd:PRK04778 167 LDEL---EKQLENLEEE-FSQFVELTEsgdyveAREILDQLEEELAAL-EQIMEEIPELLKE------LQTELPDQLQEL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1202 EDRYSQLLKQKVQLEE--LEKVLKTEQEKmLQQNEKhETVAAEYKKLRDENDRLAHTHDQL--LKENEV-----LQTDHK 1272
Cdd:PRK04778 236 KAGYRELVEEGYHLDHldIEKEIQDLKEQ-IDENLA-LLEELDLDEAEEKNEEIQERIDQLydILEREVkarkyVEKNSD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1273 NLKTLLNNSKLGQTQLEAEFSKLREEYQLLDikcTKISNQCELLSQLKgNMEEENRHLLDQI--QTL---MLQNRtlLEQ 1347
Cdd:PRK04778 314 TLPDFLEHAKEQNKELKEEIDRVKQSYTLNE---SELESVRQLEKQLE-SLEKQYDEITERIaeQEIaysELQEE--LEE 387
|
410 420 430
....*....|....*....|....*....|....*....
gi 2024492573 1348 NMESKDLFHVEQRQYIDKLNELRRQKEKLEEKImDQYKF 1386
Cdd:PRK04778 388 ILKQLEEIEKEQEKLSEMLQGLRKDELEAREKL-ERYRN 425
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
577-826 |
5.14e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 5.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 577 SAEAQMKEIEKEnkilhesIKETSSKLNKLEFEIKQVRKEMEhykEKAERAEELENELHHLEKENELLQKKIANLSitce 656
Cdd:COG3883 13 FADPQIQAKQKE-------LSELQAELEAAQAELDALQAELE---ELNEEYNELQAELEALQAEIDKLQAEIAEAE---- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 657 kiEALEKENSDLDIENRKLKKTLDSLKNLSFQLESlekenSQLDE--ENLELRRRIESSkcTSIKMAQLQLENKELESEK 734
Cdd:COG3883 79 --AEIEERREELGERARALYRSGGSVSYLDVLLGS-----ESFSDflDRLSALSKIADA--DADLLEELKADKAELEAKK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 735 EQLKKSLELMKASFKKserlevsyqgLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLE 814
Cdd:COG3883 150 AELEAKLAELEALKAE----------LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219
|
250
....*....|..
gi 2024492573 815 KENKLLEQETSQ 826
Cdd:COG3883 220 AAAAAAAAAAAA 231
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
490-650 |
5.31e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 48.24 E-value: 5.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 490 SSRIVKMEKENQRL----NKKIEELEKEIVQEKQslqdnqnlsKDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQ 565
Cdd:PRK12704 30 EAKIKEAEEEAKRIleeaKKEAEAIKKEALLEAK---------EEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 566 TIASLRQRsqisaEAQMKEIEKENKILHESIKETSSKLNKLefeIKQVRKEMEHY----KE--KAERAEELENELHH--- 636
Cdd:PRK12704 101 KLELLEKR-----EEELEKKEKELEQKQQELEKKEEELEEL---IEEQLQELERIsgltAEeaKEILLEKVEEEARHeaa 172
|
170
....*....|....*....
gi 2024492573 637 -----LEKENELLQKKIAN 650
Cdd:PRK12704 173 vlikeIEEEAKEEADKKAK 191
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
250-573 |
5.38e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 48.50 E-value: 5.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 250 VELADAKAKIRRLRQEIEEKNEQFLDYKQELERVET-------ELRRLQQENKNLLSDARSARVYRDE------------ 310
Cdd:PRK02224 377 EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDfleelreERDELREREAELEATLRTARERVEEaealleagkcpe 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 311 ----------LDILREKAIRVDKLESEVGRYKERLHDMEFYKARVEEL--MEDNQVMLETKR-----MFEDQVKTLQCRS 373
Cdd:PRK02224 457 cgqpvegsphVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLveAEDRIERLEERRedleeLIAERRETIEEKR 536
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 374 DKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEmAQKQSMDEslhlgwELEQINRFTDhSEVSHKSLGLEV 453
Cdd:PRK02224 537 ERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELN-SKLAELKE------RIESLERIRT-LLAAIADAEDEI 608
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 454 TELTSSRLLKLEKENQS--LLKTVEELRSTMDDSVGGNssRIVKMEKENQRLNKKIEELEKEIVQ---EKQSLQDNQNLS 528
Cdd:PRK02224 609 ERLREKREALAELNDERreRLAEKRERKRELEAEFDEA--RIEEAREDKERAEEYLEQVEEKLDElreERDDLQAEIGAV 686
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 2024492573 529 KDLMKEKEQLEKKFETLRENLERQIKLLEQENERSN---QTIASLRQR 573
Cdd:PRK02224 687 ENELEELEELRERREALENRVEALEALYDEAEELESmygDLRAELRQR 734
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
466-649 |
5.91e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.52 E-value: 5.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 466 KENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDL---MKEKEQLEKKF 542
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraLYRSGGSVSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 543 ETL--RENLE---RQIKLLEQENERSNQTIASLRQRsQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEM 617
Cdd:COG3883 106 DVLlgSESFSdflDRLSALSKIADADADLLEELKAD-KAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALL 184
|
170 180 190
....*....|....*....|....*....|..
gi 2024492573 618 EHYKEKAERAEELENElhhLEKENELLQKKIA 649
Cdd:COG3883 185 AQLSAEEAAAEAQLAE---LEAELAAAEAAAA 213
|
|
| TOPEUc |
smart00435 |
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ... |
501-604 |
6.17e-05 |
|
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras
Pssm-ID: 214661 [Multi-domain] Cd Length: 391 Bit Score: 47.73 E-value: 6.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 501 QRLNKKIEELEKEIVQEKQSLQDNQNLSkdlmKEKEQLEKKFETLRENLERQIKLLEQENERSNQT---IASLRQRSQiS 577
Cdd:smart00435 280 EKLQEKIKALKYQLKRLKKMILLFEMIS----DLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKkkqIERLEERIE-K 354
|
90 100
....*....|....*....|....*..
gi 2024492573 578 AEAQMKEIEkENKilheSIKETSSKLN 604
Cdd:smart00435 355 LEVQATDKE-ENK----TVALGTSKIN 376
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
455-693 |
6.21e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.00 E-value: 6.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 455 ELTSSRLLKLEKENQSLLKTVEELRSTMdDSVGGNSSRIVKMEKEN-----QRLNKKIEELEKEIVQEKQSLQDNQNLSK 529
Cdd:PRK05771 39 ELSNERLRKLRSLLTKLSEALDKLRSYL-PKLNPLREEKKKVSVKSleeliKDVEEELEKIEKEIKELEEEISELENEIK 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 530 DLMKEKEQLE--KKFETLRENL--------------ERQIKLLEQENERSNQ-TIASLRQRS----------QISAEAQM 582
Cdd:PRK05771 118 ELEQEIERLEpwGNFDLDLSLLlgfkyvsvfvgtvpEDKLEELKLESDVENVeYISTDKGYVyvvvvvlkelSDEVEEEL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 583 KEIEKENKILHES------IKETSSKLNKLEFEIKQVRKEMEHYKEKAER-----AEELENELHHLEKENELLqkkianl 651
Cdd:PRK05771 198 KKLGFERLELEEEgtpselIREIKEELEEIEKERESLLEELKELAKKYLEellalYEYLEIELERAEALSKFL------- 270
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2024492573 652 siTCEKIEALE----KENSDldienrKLKKTLDSLKNLSFQLESLE 693
Cdd:PRK05771 271 --KTDKTFAIEgwvpEDRVK------KLKELIDKATGGSAYVEFVE 308
|
|
| SH3_and_anchor |
TIGR04211 |
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ... |
719-826 |
6.45e-05 |
|
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Pssm-ID: 275056 [Multi-domain] Cd Length: 198 Bit Score: 46.15 E-value: 6.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 719 KMAQLQLENKELESEKEQLKKSLelmKASFKKSERLEVSYQGLDTENQRLQKALEnsnkKIQQLEGELQDLESENQTLQK 798
Cdd:TIGR04211 67 RLPELQQELAELQEELAELQEQL---AELRQENQELKQQLSTLEAELEELQKELE----RIKQISANAIELDEENRELRE 139
|
90 100
....*....|....*....|....*...
gi 2024492573 799 NLEELvisSKRLEQLEKENKLLEQETSQ 826
Cdd:TIGR04211 140 ELAEL---KQENEALEAENERLQENEQR 164
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
493-614 |
6.45e-05 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 47.90 E-value: 6.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 493 IVKMEKENQRLNKKIEELEKEivqekqsLQDNQNLSKDLMKEKEQLEKKFETLRENLERQI-KLLEQENERSNQTIASLR 571
Cdd:PRK00409 522 IASLEELERELEQKAEEAEAL-------LKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAqQAIKEAKKEADEIIKELR 594
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2024492573 572 QRSQISAEAQ-MKEIEKENKILHESIKETSSKLNKLEFEIKQVR 614
Cdd:PRK00409 595 QLQKGGYASVkAHELIEARKRLNKANEKKEKKKKKQKEKQEELK 638
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
505-1002 |
6.67e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 6.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 505 KKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLR-----------ENLERQIKLLEQENERSNQTIASLRQR 573
Cdd:COG4913 288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDELEaqirgnggdrlEQLEREIERLERELEERERRRARLEAL 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 574 ------SQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEhyKEKAERAEELEN----------ELHHL 637
Cdd:COG4913 368 laalglPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR--RELRELEAEIASlerrksnipaRLLAL 445
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 638 EKE-NELLQKKIANLSITCEKIE----------ALEK-----------ENSDLD-----IENRKLKKTLDSLK----NLS 686
Cdd:COG4913 446 RDAlAEALGLDEAELPFVGELIEvrpeeerwrgAIERvlggfaltllvPPEHYAaalrwVNRLHLRGRLVYERvrtgLPD 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 687 FQLESLE----------KENSQLDEENLELRRRIESSKCTSIkmAQLQLENKELESEKeQLKKSlelmKASFKKSER--- 753
Cdd:COG4913 526 PERPRLDpdslagkldfKPHPFRAWLEAELGRRFDYVCVDSP--EELRRHPRAITRAG-QVKGN----GTRHEKDDRrri 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 754 LEVSYQGLDteNQRLQKALEnsnKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQL------EKENKLLEQETSQL 827
Cdd:COG4913 599 RSRYVLGFD--NRAKLAALE---AELAELEEELAEAEERLEALEAELDALQERREALQRLaeyswdEIDVASAEREIAEL 673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 828 EKDKKQLEKEN---KRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKEscvRLKELEMENKELVKRASIDKKTL 904
Cdd:COG4913 674 EAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEE---ELDELQDRLEAAEDLARLELRAL 750
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 905 VTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSS-DDRYKLLESKL-------ESTLKKSLEIKEEKIA 976
Cdd:COG4913 751 LEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAfNREWPAETADLdadleslPEYLALLDRLEEDGLP 830
|
570 580 590
....*....|....*....|....*....|....*
gi 2024492573 977 ALEARLEES---------TNLNQQLRQELKTVKKN 1002
Cdd:COG4913 831 EYEERFKELlnensiefvADLLSKLRRAIREIKER 865
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1199-1380 |
8.31e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.45 E-value: 8.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1199 KDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHEtvaAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLL 1278
Cdd:COG4717 49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKE---EEYAELQEELEELEEELEELEAELEELREELEKLEKLL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1279 NNSKLGQT--QLEAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFH 1356
Cdd:COG4717 126 QLLPLYQEleALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQ 205
|
170 180
....*....|....*....|....
gi 2024492573 1357 VEQRQYIDKLNELRRQKEKLEEKI 1380
Cdd:COG4717 206 QRLAELEEELEEAQEELEELEEEL 229
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1047-1262 |
8.88e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.70 E-value: 8.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1047 VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ--ILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1124
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1125 MNQNAQLLIQQSALENEKE--GVLKELEDLKSLYDSLLkdheklehlhERQASEYESLIAKHGSLKSAHKNLEVEHKD-L 1201
Cdd:COG3206 246 RAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELS----------ARYTPNHPDVIALRAQIAALRAQLQQEAQRiL 315
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 1202 EDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKhetvAAEYKKLRDENDRLAHTHDQLLK 1262
Cdd:COG3206 316 ASLEAELEALQAREASLQAQLAQLEARLAELPEL----EAELRRLEREVEVARELYESLLQ 372
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
657-862 |
8.99e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 47.32 E-value: 8.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 657 KIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQldeenlELRRRIESSKCT--SIKMAQLQLENKELESEK 734
Cdd:PHA02562 175 KIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIA------RKQNKYDELVEEakTIKAEIEELTDELLNLVM 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 735 EQ---------LKKSLELMKASFKKSERLEVSY----------QGLDTENQRLQKA---LENSNKKIQQLE---GELQDL 789
Cdd:PHA02562 249 DIedpsaalnkLNTAAAKIKSKIEQFQKVIKMYekggvcptctQQISEGPDRITKIkdkLKELQHSLEKLDtaiDELEEI 328
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024492573 790 ESENQTLQKNLEELV--ISSKR--LEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHL 862
Cdd:PHA02562 329 MDEFNEQSKKLLELKnkISTNKqsLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHR 405
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
475-677 |
9.85e-05 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 47.44 E-value: 9.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 475 VEELRSTMDD-SVGGNSSRIVKMEKENQRLNK---KIEELEKEIvqEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLE 550
Cdd:pfam09731 260 QQELVSIFPDiIPVLKEDNLLSNDDLNSLIAHahrEIDQLSKKL--AELKKREEKHIERALEKQKEELDKLAEELSARLE 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 551 RQIKLLEQENERSNQtiaSLRQRSQISAEAQMK-EIEKENKILHESIKEtssklnklefEIKQVRKEMehykeKAERAEE 629
Cdd:pfam09731 338 EVRAADEAQLRLEFE---REREEIRESYEEKLRtELERQAEAHEEHLKD----------VLVEQEIEL-----QREFLQD 399
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2024492573 630 LENelhHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKK 677
Cdd:pfam09731 400 IKE---KVEEERAGRLLKLNELLANLKGLEKATSSHSEVEDENRKAQQ 444
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
483-660 |
9.94e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.75 E-value: 9.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 483 DDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLE----- 557
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGerara 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 558 -QENERSNQTIASL----------RQRSQIS--AEAQMKEIEKENKiLHESIKETSSKLNKLEFEIKQVRKEMEHYKEKA 624
Cdd:COG3883 95 lYRSGGSVSYLDVLlgsesfsdflDRLSALSkiADADADLLEELKA-DKAELEAKKAELEAKLAELEALKAELEAAKAEL 173
|
170 180 190
....*....|....*....|....*....|....*..
gi 2024492573 625 ERA-EELENELHHLEKENELLQKKIANLSITCEKIEA 660
Cdd:COG3883 174 EAQqAEQEALLAQLSAEEAAAEAQLAELEAELAAAEA 210
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
504-1294 |
1.03e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 47.90 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 504 NKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQEnersnQTIASLRQRSQISAEA--- 580
Cdd:PTZ00440 449 DEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDELL-----QIINSIKEKNNIVNNNfkn 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 581 ------QMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANL--- 651
Cdd:PTZ00440 524 iedyyiTIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENVDHIKDIISLNDEIDNIIQQIeel 603
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 652 -SITCEKIEALEKENSDL---------DIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRI-ESSKCTSIKM 720
Cdd:PTZ00440 604 iNEALFNKEKFINEKNDLqekvkyilnKFYKGDLQELLDELSHFLDDHKYLYHEAKSKEDLQTLLNTSKnEYEKLEFMKS 683
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 721 AQLQLENKELESEKEQ---LKKSLELMKASFKKSERLEVSYQGLDTENQrLQKALENSNKKIQQLEGELQDLESENQ--- 794
Cdd:PTZ00440 684 DNIDNIIKNLKKELQNllsLKENIIKKQLNNIEQDISNSLNQYTIKYND-LKSSIEEYKEEEEKLEVYKHQIINRKNefi 762
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 795 -TLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKE---NKRLRQQAEIKDSTLEENNVKinHLEKENKSLf 870
Cdd:PTZ00440 763 lHLYENDKDLPDGKNTYEEFLQYKDTILNKENKISNDINILKENkknNQDLLNSYNILIQKLEAHTEK--NDEELKQLL- 839
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 871 kQIAVYKESCVRLKELEMENKELVKRAS--------------IDKKTLVTLREDLVNEKLKTQQMNND---LEKLSHELE 933
Cdd:PTZ00440 840 -QKFPTEDENLNLKELEKEFNENNQIVDniikdienmnkninIIKTLNIAINRSNSNKQLVEHLLNNKidlKNKLEQHMK 918
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 934 KIG----------------LNKERLLCDEQSSDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNLN---QQLRQ 994
Cdd:PTZ00440 919 IINtdniiqkneklnllnnLNKEKEKIEKQLSDTKINNLKMQIEKTLEYYDKSKENINGNDGTHLEKLDKEKdewEHFKS 998
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 995 ELKTVKKNYEALKQR------QEEERMVQNPPPRKGEENQSVNKWEKENQETTREL---LKVKDRLIEVER-NNATLQAE 1064
Cdd:PTZ00440 999 EIDKLNVNYNILNKKiddlikKQHDDIIELIDKLIKEKGKEIEEKVDQYISLLEKMktkLSSFHFNIDIKKyKNPKIKEE 1078
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1065 KQALKTQLKQLETQNNNLQAQILALQRqtvsLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENEKEG 1144
Cdd:PTZ00440 1079 IKLLEEKVEALLKKIDENKNKLIEIKN----KSHEHVVNADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDI 1154
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1145 VLKELEDLKSLYDSLLKDH--EKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDR------YSQLLKQKVQLE 1216
Cdd:PTZ00440 1155 TLNEVNEIEIEYERILIDHivEQINNEAKKSKTIMEEIESYKKDIDQVKKNMSKERNDHLTTfeynayYDKATASYENIE 1234
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1217 ELEKVLKTEQEK------MLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKN--LKTLLNNSKLGQT-- 1286
Cdd:PTZ00440 1235 ELTTEAKGLKGEanrstnVDELKEIKLQVFSYLQQVIKENNKMENALHEIKNMYEFLISIDSEkiLKEILNSTKKAEEfs 1314
|
....*....
gi 2024492573 1287 -QLEAEFSK 1294
Cdd:PTZ00440 1315 nDAKKELEK 1323
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
889-1169 |
1.06e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.43 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 889 ENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEK---IGLNKERLLCDEQSSDDRYKLLESK--LEST 963
Cdd:pfam17380 286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRqaaIYAEQERMAMERERELERIRQEERKreLERI 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 964 LKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKN--YEALKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETT 1041
Cdd:pfam17380 366 RQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVkiLEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1042 RELLKVkdRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQtqnAKLQVENSTLNSQS 1121
Cdd:pfam17380 446 REMERV--RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQ---AMIEEERKRKLLEK 520
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2024492573 1122 TSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHL 1169
Cdd:pfam17380 521 EMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRL 568
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
284-1074 |
1.16e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.12 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 284 ETELRRLQQENKNLlsdarsarvyRDELDilrekaIRVDKLESEVGRYKErLHDMEFYKARVEELMEDNQVMLetkrmFE 363
Cdd:pfam10174 2 QAQLRDLQRENELL----------RRELD------IKESKLGSSMNSIKT-FWSPELKKERALRKEEAARISV-----LK 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 364 DQVKTLQCRSDKLHvvekenLQLKAKLHEMEMERDMDrkkieELMEEnmalEMAQKQSMDESLHLGWELEQINRFTDHSE 443
Cdd:pfam10174 60 EQYRVTQEENQHLQ------LTIQALQDELRAQRDLN-----QLLQQ----DFTTSPVDGEDKFSTPELTEENFRRLQSE 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 444 VSHKSlglevteltssrllkleKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEK-----ENQRLNKKIEELEKEivqEK 518
Cdd:pfam10174 125 HERQA-----------------KELFLLRKTLEEMELRIETQKQTLGARDESIKKllemlQSKGLPKKSGEEDWE---RT 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 519 QSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLL-EQENERSNQTIASLRQRSQISAEAQMKEIEKENKILhesik 597
Cdd:pfam10174 185 RRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQpDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQML----- 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 598 ETSSKLN--KLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKkianlsitceKIEALEKENSDldienrkL 675
Cdd:pfam10174 260 KTNGLLHteDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQT----------KLETLTNQNSD-------C 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 676 KKTLDSLKNlsfQLESLEKENSQLDEENLELRRRIESSKCT-SIKMAQLQlenkELESEKEQLKKSLELMKASFKKSERl 754
Cdd:pfam10174 323 KQHIEVLKE---SLTAKEQRAAILQTEVDALRLRLEEKESFlNKKTKQLQ----DLTEEKSTLAGEIRDLKDMLDVKER- 394
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 755 evSYQGLDTENQRLQKALENSNKKIQQLEGELQDLE---SENQTLQKNLEELVISSKRLEQLEKENKllEQETSQLEKDK 831
Cdd:pfam10174 395 --KINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQtdsSNTDTALTTLEEALSEKERIIERLKEQR--EREDRERLEEL 470
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 832 KQLEKENKRLRQQAEIKDSTLEENNVKINHLeKENKSLFKQIAVYKESCVRLKELEMENK--ELVKRASIDKKTlvtlre 909
Cdd:pfam10174 471 ESLKKENKDLKEKVSALQPELTEKESSLIDL-KEHASSLASSGLKKDSKLKSLEIAVEQKkeECSKLENQLKKA------ 543
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 910 dlvNEKLKTQQMNNDL-EKLSHELEKIGLNKERllcDEQSSDDRYKLLESKLESTLKKSLeiKEEKIAALearleESTNL 988
Cdd:pfam10174 544 ---HNAEEAVRTNPEInDRIRLLEQEVARYKEE---SGKAQAEVERLLGILREVENEKND--KDKKIAEL-----ESLTL 610
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 989 NQQLRQELKTVKKNYEALKQRQEEERMVQNppPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQ---AEK 1065
Cdd:pfam10174 611 RQMKEQNKKVANIKHGQQEMKKKGAQLLEE--ARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQqslAEK 688
|
....*....
gi 2024492573 1066 QALKTQLKQ 1074
Cdd:pfam10174 689 DGHLTNLRA 697
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
498-792 |
1.24e-04 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 46.98 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 498 KENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKF-------------ETLRENL----------ERQIK 554
Cdd:pfam13166 89 EESIEIQEKIAKLKKEIKDHEEKLDAAEANLQKLDKEKEKLEADFldecwkkikrkknSALSEALngfkyeanfkSRLLR 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 555 LLEQENeRSNQTIASLRQRSQISAEA---QMKEIEK--ENKILHESIKETS---SKLNKLEFEIKQVRKE---------- 616
Cdd:pfam13166 169 EIEKDN-FNAGVLLSDEDRKAALATVfsdNKPEIAPltFNVIDFDALEKAEiliQKVIGKSSAIEELIKNpdladwveqg 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 617 MEHYKE------------KAERAEELENelhHLEKENELLQKKIANL--SITCEKIEALEKEN--SDLDIENRKLKKTLD 680
Cdd:pfam13166 248 LELHKAhldtcpfcgqplPAERKAALEA---HFDDEFTEFQNRLQKLieKVESAISSLLAQLPavSDLASLLSAFELDVE 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 681 SLKNLSFQLESLEKENSQ-LDEENLELRRRIESS----KCTSIKMAQLQLEN---------KELESEKEQLKKSLELMKA 746
Cdd:pfam13166 325 DIESEAEVLNSQLDGLRRaLEAKRKDPFKSIELDsvdaKIESINDLVASINEliakhneitDNFEEEKNKAKKKLRLHLV 404
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 2024492573 747 SFKKSE--RLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESE 792
Cdd:pfam13166 405 EEFKSEidEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIKELEAQ 452
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
259-506 |
1.28e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 46.34 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 259 IRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLsdARSARVYRDELDILREKAIRVDKLESEVGRYKERLHDM 338
Cdd:pfam15905 82 IRALVQERGEQDKRLQALEEELEKVEAKLNAAVREKTSLS--ASVASLEKQLLELTRVNELLKAKFSEDGTQKKMSSLSM 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 339 EFYKARvEELMEDNQVMLETKRMFEDQVKTLQcrsDKLHVVEKENLQLKAKLHEMEMERDMDRKKIEELMEENMALEMAQ 418
Cdd:pfam15905 160 ELMKLR-NKLEAKMKEVMAKQEGMEGKLQVTQ---KNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVS 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 419 KQSMDESLHLGWELEQINRFTDHSEVSHKSLGLEVTELT------SSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSR 492
Cdd:pfam15905 236 EQVEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSkqikdlNEKCKLLESEKEELLREYEEKEQTLNAELEELKEK 315
|
250
....*....|....
gi 2024492573 493 IVKMEKENQRLNKK 506
Cdd:pfam15905 316 LTLEEQEHQKLQQK 329
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
624-859 |
1.32e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 1.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 624 AERAEELENELHHLEKENELLQKKIANLSitcEKIEALEKENSDLDIENRkLKKTLDSLKNLSFQLESLEKENSQLDEEN 703
Cdd:COG3206 167 ELRREEARKALEFLEEQLPELRKELEEAE---AALEEFRQKNGLVDLSEE-AKLLLQQLSELESQLAEARAELAEAEARL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 704 LELRRRIESSKCTSIKMAQLQlENKELESEKEQLKKSLELMKASFKKSERlevSYQGLDTENQRLQKALEnsnkkiQQLE 783
Cdd:COG3206 243 AALRAQLGSGPDALPELLQSP-VIQQLRAQLAELEAELAELSARYTPNHP---DVIALRAQIAALRAQLQ------QEAQ 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 784 GELQDLESENQTLQKNLEELvisSKRLEQLEKENKLL---EQETSQLEKDKKQLEKENKRL---RQQAEIkDSTLEENNV 857
Cdd:COG3206 313 RILASLEAELEALQAREASL---QAQLAQLEARLAELpelEAELRRLEREVEVARELYESLlqrLEEARL-AEALTVGNV 388
|
..
gi 2024492573 858 KI 859
Cdd:COG3206 389 RV 390
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
734-1027 |
1.39e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 46.43 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 734 KEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESEnqtLQKNLEELVISSKRLEQL 813
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ---LQAAQAELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 814 EKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEmENKEL 893
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE-AEQAL 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 894 VKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERllcDEQSSDDRYKLLESKLESTLKKSLEIKEE 973
Cdd:COG4372 186 DELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGL---ALSALLDALELEEDKEELLEEVILKEIEE 262
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 2024492573 974 KIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEEN 1027
Cdd:COG4372 263 LELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDA 316
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1062-1251 |
1.39e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.36 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1062 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQstsLMNQNAQLLIQQSALEN- 1140
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGEr 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1141 -----EKEGVLKELEDL---KSLYDsLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDrysQLLKQK 1212
Cdd:COG3883 92 aralyRSGGSVSYLDVLlgsESFSD-FLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEA---LKAELE 167
|
170 180 190
....*....|....*....|....*....|....*....
gi 2024492573 1213 VQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDEND 1251
Cdd:COG3883 168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELA 206
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
601-786 |
1.53e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.30 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 601 SKLNKLEFEIKQVRKEmehYKEKAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDldienrKLK--KT 678
Cdd:COG1579 17 SELDRLEHRLKELPAE---LAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE------QLGnvRN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 679 LDSLKNLSFQLESLEKENSQLDEENLELRRRIEsskctsikmaQLQLENKELESEKEQLKKSLELMKASfkkserlevsy 758
Cdd:COG1579 88 NKEYEALQKEIESLKRRISDLEDEILELMERIE----------ELEEELAELEAELAELEAELEEKKAE----------- 146
|
170 180
....*....|....*....|....*...
gi 2024492573 759 qgLDTENQRLQKALENSNKKIQQLEGEL 786
Cdd:COG1579 147 --LDEELAELEAELEELEAEREELAAKI 172
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
690-1076 |
1.69e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.43 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 690 ESLEKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESE----KEQLKKSLELMKASFKKSERLEVSYQGLDTEN 765
Cdd:pfam07888 38 ECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRvaelKEELRQSREKHEELEEKYKELSASSEELSEEK 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 766 QRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENkllEQETSQLEKDKKQLEKENKRLRQQA 845
Cdd:pfam07888 118 DALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE---EAERKQLQAKLQQTEEELRSLSKEF 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 846 EIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLvnEKLKTQQMNNDL 925
Cdd:pfam07888 195 QELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEEL--SSMAAQRDRTQA 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 926 EKLSHELEKIGLNKerllcdeQSSDDRYKLLE-----SKLESTLKKSLEIKEEKIAALEARLEEStnlnQQLRQELKTVK 1000
Cdd:pfam07888 273 ELHQARLQAAQLTL-------QLADASLALREgrarwAQERETLQQSAEADKDRIEKLSAELQRL----EERLQEERMER 341
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 1001 KNYEALKQRQEEERMVQNppprkgeenqsvnkwekenQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1076
Cdd:pfam07888 342 EKLEVELGREKDCNRVQL-------------------SESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
240-570 |
1.84e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.59 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 240 KHTESKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKNLLSDARSArvyRDELDILREkai 319
Cdd:TIGR02168 737 RLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL---REALDELRA--- 810
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 320 RVDKLESEVGRYKERLHDMEFYKARVEELMEDNQvmLETKRMFEDQVKTLQCRSDKLHVVEKENLQLKAKLHEME-MERD 398
Cdd:TIGR02168 811 ELTLLNEEAANLRERLESLERRIAATERRLEDLE--EQIEELSEDIESLAAEIEELEELIEELESELEALLNERAsLEEA 888
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 399 MD--RKKIEELMEENMALEMAQKQSMDESLHLGWELEQINrftdhsevshksLGLEVTELTSSRLL-KLEKENQSLLKTV 475
Cdd:TIGR02168 889 LAllRSELEELSEELRELESKRSELRRELEELREKLAQLE------------LRLEGLEVRIDNLQeRLSEEYSLTLEEA 956
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 476 EELRSTMDDSVGGNSSRIVKMEKENQRLNK----KIEELEKeiVQEKQSLQDNQnlSKDLMKEKEQLEKKFETL-RENLE 550
Cdd:TIGR02168 957 EALENKIEDDEEEARRRLKRLENKIKELGPvnlaAIEEYEE--LKERYDFLTAQ--KEDLTEAKETLEEAIEEIdREARE 1032
|
330 340
....*....|....*....|
gi 2024492573 551 RQIKLLEQENERSNQTIASL 570
Cdd:TIGR02168 1033 RFKDTFDQVNENFQRVFPKL 1052
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
307-714 |
1.92e-04 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 46.58 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 307 YRDELDILREkairvdklesevgRYKERLhdmEFYKARVE---ELMEDNQVMLETKRMFEDQVktlqcRSDKLHVVEKEN 383
Cdd:PTZ00108 975 YSDALDILKE-------------FYLVRL---DLYKKRKEyllGKLERELARLSNKVRFIKHV-----INGELVITNAKK 1033
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 384 LQLKAKLHEMEMERdmdRKKIEELMEENMALEMAQKQSMDEslhlgwelEQINRFTDHSEVSHKS----LGLEVTELTSS 459
Cdd:PTZ00108 1034 KDLVKELKKLGYVR---FKDIIKKKSEKITAEEEEGAEEDD--------EADDEDDEEELGAAVSydylLSMPIWSLTKE 1102
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 460 RLLKLEKENQSLLKTVEELRSTmddsvggnssRIVKMEKEN-QRLNKKIEELEKEIVQEKQ----------SLQDNQNLS 528
Cdd:PTZ00108 1103 KVEKLNAELEKKEKELEKLKNT----------TPKDMWLEDlDKFEEALEEQEEVEEKEIAkeqrlksktkGKASKLRKP 1172
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 529 KDLMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQMKEIEKENKILHESIKETSSKLNKLEF 608
Cdd:PTZ00108 1173 KLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSK 1252
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 609 EIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIEN--RKLKKTLDSLKNLS 686
Cdd:PTZ00108 1253 SSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLEGslAALKKKKKSEKKTA 1332
|
410 420
....*....|....*....|....*...
gi 2024492573 687 FQLESLEKENSQLDEENLELRRRIESSK 714
Cdd:PTZ00108 1333 RKKKSKTRVKQASASQSSRLLRRPRKKK 1360
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
1041-1356 |
1.96e-04 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 45.83 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1041 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQletqnnnLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQ 1120
Cdd:pfam15742 33 EKELRYERGKNLDLKQHNSLLQEENIKIKAELKQ-------AQQKLLDSTKMCSSLTAEWKHCQQKIRELELEVLKQAQS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1121 STSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLE----HLHERQASEYESliakhgSLKSAHKNLEV 1196
Cdd:pfam15742 106 IKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHAHKVCLTDTCILEkkqlEERIKEASENEA------KLKQQYQEEQQ 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1197 EHKDLEDRYSQLLKQKVQLEELEKVLK---TEQEKMLQQNEKHETVAAEYKKLRDE----NDRLAHTHDQLLKENEVLQT 1269
Cdd:pfam15742 180 KRKLLDQNVNELQQQVRSLQDKEAQLEmtnSQQQLRIQQQEAQLKQLENEKRKSDEhlksNQELSEKLSSLQQEKEALQE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1270 DHKNLKTLLN----NSKLGQTQLEAEFSKLRE----EYQLLDIKCTKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQN 1341
Cdd:pfam15742 260 ELQQVLKQLDvhvrKYNEKHHHHKAKLRRAKDrlvhEVEQRDERIKQLENEIGILQQQSEKEKAFQKQVTAQNEILLLEK 339
|
330
....*....|....*
gi 2024492573 1342 RTLLEQNMESKDLFH 1356
Cdd:pfam15742 340 RKLLEQLTEQEELIK 354
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
374-1043 |
2.14e-04 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 46.70 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 374 DKLHVVEKENLQLKAKLHEMEMERDmdRKKIEELMEENMALEMAQKQSMDESlhlgWELEQINRFTDHSEVSHKSLGLEV 453
Cdd:PTZ00341 426 DMLDGSEDESVEDNEEEHSGDANEE--ELSVDEHVEEHNADDSGEQQSDDES----GEHQSVNEIVEEQSVNEHVEEPTV 499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 454 TELTSSRLLKLEKENQSLLKTVEElrSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQ---SLQDNQNLSKD 530
Cdd:PTZ00341 500 ADIVEQETVDEHVEEPAVDENEEQ--QTADEHVEEPTIAEEHVEEEISTAEEHIEEPASDVQQDSEaapTIEIPDTLFYD 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 531 LMKEKEQLEkkfetLRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQ-MKEIEKE---NKILHESIKETS------ 600
Cdd:PTZ00341 578 ILGVGVNAD-----MKEISERYFKLAENYYPPKRSGNEGFHKFKKINEAYQiLGDIDKKkmyNKFGYDGIKGVNfihpsi 652
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 601 ----SKLNKLEFEI--KQVRKEMEHYKEKAERAEELENELHHLEKENELLQKKiANLSITCEKIEALEKENSDLDIENRK 674
Cdd:PTZ00341 653 fyllASLEKFADFTgsPQIVTLLKFFFEKKLSMNDLDNKSEHLLKFMEQYQKE-REAHISENLINILQPCIAGDRKWDVP 731
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 675 LKKTLDSLKNLSFQLESLEKENSQLDEENLElrrRIESSKCTSIKMAQLQLENKE-LESEKEQLkksLELMKASFKKSER 753
Cdd:PTZ00341 732 IIDKIEELKGSPFDIAIIDSIGWIFKHVAKS---HLKKPKKAAKKLEQRSKANKEeLANENNKL---MNILKEYFGNNEQ 805
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 754 LE-----VSYQGLDTENQRLQKALENSNKKIQQ----------LEGELQDLE-----SENQTLQKNLEELVISSKRLEQL 813
Cdd:PTZ00341 806 INsitynFENINLNEDNENGSKKILDLNHKDQKeifeeiisyiVDISLSDIEntaknAAEQILSDEGLDEKKLKKRAESL 885
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 814 EKENKLLEQETSQLEKDKKQLEKE---------------NKRLRQQAEIKDSTLEEN-NVKINHLEKENKSLFKQIAVYK 877
Cdd:PTZ00341 886 KKLANAIEKYAGGGKKDKKAKKKDakdlsgniaheinliNKELKNQNENVPEHLKEHaEANIEEDAEENVEEDAEENVEE 965
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 878 ESCVRLKELEMENKELVKRASIDKKTLVTLREDL-------VNEKLKTQQMNNDLEKLSHELEKIGLNKERLlcDEQSSD 950
Cdd:PTZ00341 966 NVEENVEENVEENVEENVEENVEENVEENVEENVeenieenVEENVEENIEENVEEYDEENVEEVEENVEEY--DEENVE 1043
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 951 DRYKLLESKLESTLKKSLE-IKEEKIAALEARLEESTNLNQQlrqelKTVKKNYEALKQRQEEErmVQNPPPRKGEENQS 1029
Cdd:PTZ00341 1044 EIEENAEENVEENIEENIEeYDEENVEEIEENIEENIEENVE-----ENVEENVEEIEENVEEN--VEENAEENAEENAE 1116
|
730
....*....|....
gi 2024492573 1030 VNKwEKENQETTRE 1043
Cdd:PTZ00341 1117 ENA-EEYDDENPEE 1129
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
981-1380 |
2.23e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.21 E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 981 RLEESTNLNQQLRQELKTVKKNYEALKQRQEE-ERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVE---- 1055
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENiEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEelke 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1056 ------RNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNttlqtQNAKLQVENSTLNSQSTSLMNQNA 1129
Cdd:PRK03918 239 eieeleKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELK-----EKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1130 QLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHER---QASEYESLIAKHG---SLKSAHKNLEVEhkDLED 1203
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEleeRHELYEEAKAKKEeleRLKKRLTGLTPE--KLEK 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1204 RYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDE----NDRLAHTHdqllkENEVLQTDHKNLKTLLN 1279
Cdd:PRK03918 392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcGRELTEEH-----RKELLEEYTAELKRIEK 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1280 NSKlgqtQLEAEFSKLREEYQLLDI---KCTKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNRTLLEQNME-SKDLF 1355
Cdd:PRK03918 467 ELK----EIEEKERKLRKELRELEKvlkKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKlKGEIK 542
|
410 420
....*....|....*....|....*
gi 2024492573 1356 HVEQRqyIDKLNELRRQKEKLEEKI 1380
Cdd:PRK03918 543 SLKKE--LEKLEELKKKLAELEKKL 565
|
|
| HlpA |
COG2825 |
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ... |
495-591 |
2.41e-04 |
|
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 43.67 E-value: 2.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 495 KMEKENQRLNKKIEELEKEIVQEKQSLQDNQ-NLSKDlmkEKEQLEKKFETLRENLERQIKLLEQENERSNQtiaSLRQR 573
Cdd:COG2825 47 KLEKEFKKRQAELQKLEKELQALQEKLQKEAaTLSEE---ERQKKERELQKKQQELQRKQQEAQQDLQKRQQ---ELLQP 120
|
90
....*....|....*...
gi 2024492573 574 SQISAEAQMKEIEKENKI 591
Cdd:COG2825 121 ILEKIQKAIKEVAKEEGY 138
|
|
| PHA01351 |
PHA01351 |
putative minor structural protein |
1066-1308 |
2.42e-04 |
|
putative minor structural protein
Pssm-ID: 107029 Cd Length: 1070 Bit Score: 46.48 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1066 QALKTQLKQLETQNNNLQAQ--ILALQRQTVSL-----QEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNaQLLIQQSAL 1138
Cdd:PHA01351 462 EEVRTVFDTMITQSQLIQTNqlLLRQLQQIVSLgifdqKKIKEELKANKFNEQVALQILESELQFAQLQN-QLKEYQFKL 540
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1139 EN---EKEGVLKELEDL--KSLYDSLLKDHEKLEHLHERQASEYESLiAKHGSL-----KSAHKNLEVEhKDLEDRYSQL 1208
Cdd:PHA01351 541 NNfliSPQDLEKDLKHLgfDSAIISALIYENQVEQLIKFQLNNIESL-AKKGYLsldeiKKQFKAIGII-KEYEDAFINF 618
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1209 LKQKVQLEELEKVLKTEQEKMLQQNEKHETvaaEYKKLrDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKLGQTQL 1288
Cdd:PHA01351 619 YNQELQISAFLTILKSQLRQFQIDPKEAET---ELKKL-NINEYLANQIIQEEYNINIAKLQLSVLETIAKTLYYDQQQL 694
|
250 260
....*....|....*....|
gi 2024492573 1289 EAEFSKLREEYQLLDIKCTK 1308
Cdd:PHA01351 695 SGELKKIHKDKTALELYITK 714
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
721-1017 |
2.49e-04 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 46.17 E-value: 2.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 721 AQLQLENKELESEKEQLKKSLELMKASFKKSERlevsyqgldtenQRLQKALENSNKK-IQQLEGELQDLESENQTLQKN 799
Cdd:pfam05667 213 AAELAAAQEWEEEWNSQGLASRLTPEEYRKRKR------------TKLLKRIAEQLRSaALAGTEATSGASRSAQDLAEL 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 800 LEELVISSKRLEQLEK------ENKLL---EQETSQLEKDKKQLEKENKRLRQQAEIKD--STLEENNVKINHLEKENKS 868
Cdd:pfam05667 281 LSSFSGSSTTDTGLTKgsrfthTEKLQftnEAPAATSSPPTKVETEEELQQQREEELEElqEQLEDLESSIQELEKEIKK 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 869 LFKQIavyKESCVRLKELEMENKELVKRASIDKKTLVTLREDLVN-EKLKT--QQMNNDLEKLSHELEK--IGLNKE--- 940
Cdd:pfam05667 361 LESSI---KQVEEELEELKEQNEELEKQYKVKKKTLDLLPDAEENiAKLQAlvDASAQRLVELAGQWEKhrVPLIEEyra 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 941 -RLLCDEQSSDDRYKLLESK-LESTLKKSLE---IKEEKIAALEARLE---ESTNLNQQLRQELKTVkKNYEalKQRQEE 1012
Cdd:pfam05667 438 lKEAKSNKEDESQRKLEEIKeLREKIKEVAEeakQKEELYKQLVAEYErlpKDVSRSAYTRRILEIV-KNIK--KQKEEI 514
|
....*
gi 2024492573 1013 ERMVQ 1017
Cdd:pfam05667 515 TKILS 519
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
583-1030 |
2.56e-04 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 46.19 E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 583 KEIEKENKILHE---SIKETSSKlNKLEFEIKQVRKEMEHYKEkaeraEELENELHhlekenelLQKKIANLSITCEKIE 659
Cdd:PTZ00108 904 EFLESETLKEKDvivDYRDYSTA-NTVHFTVKLNDGVLEQWEE-----EGIEKVFK--------LKSTISTTNMVLFDEN 969
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 660 A-LEKENSDLDIENRKLKKTLDSLKNL-SFQLESLEKENSQLD----------EENLELRRRiesSKCTSIKmaqlQLEN 727
Cdd:PTZ00108 970 GkIKKYSDALDILKEFYLVRLDLYKKRkEYLLGKLERELARLSnkvrfikhviNGELVITNA---KKKDLVK----ELKK 1042
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 728 KELESEKEQLKKSLELMKAsFKKSERLEVSYQGLDTENQRLQKALEN-----------SNKKIQQLEGELQDLESENQTL 796
Cdd:PTZ00108 1043 LGYVRFKDIIKKKSEKITA-EEEEGAEEDDEADDEDDEEELGAAVSYdyllsmpiwslTKEKVEKLNAELEKKEKELEKL 1121
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 797 QKN------LEELVISSKRLEQLEKENKLLEQETSQLE---------KDKKQLEKENKRLRQQAEIKDSTLEENNVKINH 861
Cdd:PTZ00108 1122 KNTtpkdmwLEDLDKFEEALEEQEEVEEKEIAKEQRLKsktkgkaskLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRV 1201
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 862 LEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELEKIglnkER 941
Cdd:PTZ00108 1202 DSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAP----KR 1277
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 942 LLCDEQSSDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERmVQNPPP 1021
Cdd:PTZ00108 1278 VSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSS-RLLRRP 1356
|
....*....
gi 2024492573 1022 RKGEENQSV 1030
Cdd:PTZ00108 1357 RKKKSDSSS 1365
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
244-361 |
2.65e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 46.00 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 244 SKQHLSVELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQEnknlLSDARSARvyrdELDILREKAIRvdK 323
Cdd:COG2433 400 EKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERE----LSEARSEE----RREIRKDREIS--R 469
|
90 100 110
....*....|....*....|....*....|....*...
gi 2024492573 324 LESEVGRYKERLHDMEfykARVEELMEDNQVMLETKRM 361
Cdd:COG2433 470 LDREIERLERELEEER---ERIEELKRKLERLKELWKL 504
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
248-690 |
2.75e-04 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 45.82 E-value: 2.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 248 LSVELADAKAKIRRLRQEIEEKNEQfldykqeLERVETELRRLQQENKNLLSDarsarvYRDELDILREKAIRVDKLESE 327
Cdd:pfam13166 87 LGEESIEIQEKIAKLKKEIKDHEEK-------LDAAEANLQKLDKEKEKLEAD------FLDECWKKIKRKKNSALSEAL 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 328 VGRYKErlhdmEFYKARVEELMEDNQVmletkrmFEDQVKTLQCRSDKLHVVEKENLQLKAKLHEMEMERDMDRKkiEEL 407
Cdd:pfam13166 154 NGFKYE-----ANFKSRLLREIEKDNF-------NAGVLLSDEDRKAALATVFSDNKPEIAPLTFNVIDFDALEK--AEI 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 408 MEENMALEMAQKQSMDESLHLG-WELEQINRFTDHSEvshkSLGLEVTELTSSRllklekenqsllktVEELRSTMDDSV 486
Cdd:pfam13166 220 LIQKVIGKSSAIEELIKNPDLAdWVEQGLELHKAHLD----TCPFCGQPLPAER--------------KAALEAHFDDEF 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 487 ggnssrivkmEKENQRLNKKIEELEKEIVQEKQSLQD----------NQNLSKDLMKEKEQLEKKFETLRENLERQIKLL 556
Cdd:pfam13166 282 ----------TEFQNRLQKLIEKVESAISSLLAQLPAvsdlasllsaFELDVEDIESEAEVLNSQLDGLRRALEAKRKDP 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 557 EQENERSnQTIASLRQRSQISAEAQmKEIEKENKILHESIKETSSKLNKLE-FEIKQVRKEMEHYKEKAERaeeLENELH 635
Cdd:pfam13166 352 FKSIELD-SVDAKIESINDLVASIN-ELIAKHNEITDNFEEEKNKAKKKLRlHLVEEFKSEIDEYKDKYAG---LEKAIN 426
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 636 HLEKENELLQKKIANLSitcEKIEALEKENSD----LDIENRKLKKTLdsLKNLSFQLE 690
Cdd:pfam13166 427 SLEKEIKNLEAEIKKLR---EEIKELEAQLRDhkpgADEINKLLKAFG--FGELELSFN 480
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
923-1377 |
2.90e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.83 E-value: 2.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 923 NDLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLK--KSLEIKEEKIAA-----------LEARLEESTNLN 989
Cdd:PRK03918 165 KNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLReiNEISSELPELREeleklekevkeLEELKEEIEELE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 990 QQLRQELKTVKKNYEALKQRQ---EEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLIEVERNNATLQAEKQ 1066
Cdd:PRK03918 245 KELESLEGSKRKLEEKIRELEeriEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1067 ALKTQLKQLETQN---NNLQAQILALQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQ-SALENEK 1142
Cdd:PRK03918 325 GIEERIKELEEKEerlEELKKKLKELEKRLEELEERHELYEEAKAKK----EELERLKKRLTGLTPEKLEKElEELEKAK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1143 EGVLKELEDLKSLYDSLLKDHEKLEHLHERQAS---------------EYESLIAKHgslKSAHKNLEVEHKDLEDRYSQ 1207
Cdd:PRK03918 401 EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelteeHRKELLEEY---TAELKRIEKELKEIEEKERK 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1208 LLKQKVqleELEKVLKTEQEKMlqqneKHETVAAEYKKLRDENDRLAhthdqlLKENEVLQTDHKNLKTLLNNSKLGQTQ 1287
Cdd:PRK03918 478 LRKELR---ELEKVLKKESELI-----KLKELAEQLKELEEKLKKYN------LEELEKKAEEYEKLKEKLIKLKGEIKS 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1288 LEAEFSKLREeyqlldikctkISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLN 1367
Cdd:PRK03918 544 LKKELEKLEE-----------LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEK 612
|
490
....*....|
gi 2024492573 1368 ELRRQKEKLE 1377
Cdd:PRK03918 613 ELEREEKELK 622
|
|
| OmpH |
smart00935 |
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ... |
495-591 |
3.33e-04 |
|
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.
Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 42.57 E-value: 3.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 495 KMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDlmKEKEQLEKKFETLRENLERQIKLLEQENERSNQtiaSLRQRS 574
Cdd:smart00935 22 QLEKEFKKRQAELEKLEKELQKLKEKLQKDAATLSE--AAREKKEKELQKKVQEFQRKQQKLQQDLQKRQQ---EELQKI 96
|
90
....*....|....*..
gi 2024492573 575 QISAEAQMKEIEKENKI 591
Cdd:smart00935 97 LDKINKAIKEVAKKKGY 113
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
459-629 |
3.47e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 3.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 459 SRLLKLEKENQSLLKTVEELRSTMDdsvgGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQl 538
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELA----ALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEY- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 539 ekkfetlrENLERQIKLLEQENERSNQTIASLRQRsqisAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEME 618
Cdd:COG1579 92 --------EALQKEIESLKRRISDLEDEILELMER----IEELEEELAELEAELAELEAELEEKKAELDEELAELEAELE 159
|
170
....*....|.
gi 2024492573 619 HYKEKAERAEE 629
Cdd:COG1579 160 ELEAEREELAA 170
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
956-1117 |
3.60e-04 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 43.38 E-value: 3.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 956 LESKLESTLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKnyealkqrqeeermvqnpppRKGEENQSVNkwek 1035
Cdd:pfam08614 26 LQSEPESVLPSTSSSKLSKASPQSASIQSLEQLLAQLREELAELYR--------------------SRGELAQRLV---- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1036 enqETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENS 1115
Cdd:pfam08614 82 ---DLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRKLEKENR 158
|
..
gi 2024492573 1116 TL 1117
Cdd:pfam08614 159 EL 160
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
719-837 |
4.89e-04 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 42.29 E-value: 4.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 719 KMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEgelQDLESENQTLQK 798
Cdd:pfam12718 22 KVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLKEAKEKAEESEKLKTNNENLTRKIQLLE---EELEESDKRLKE 98
|
90 100 110
....*....|....*....|....*....|....*....
gi 2024492573 799 NLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKE 837
Cdd:pfam12718 99 TTEKLRETDVKAEHLERKVQALEQERDEWEKKYEELEEK 137
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
594-844 |
5.19e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 44.13 E-value: 5.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 594 ESIKETSSKLNKLEFEIKQVRKEMEHYKEKaerAEELENELHHL-EKENELLQKkianlsiTCEKIEALEKENSDLDIEN 672
Cdd:COG1340 1 SKTDELSSSLEELEEKIEELREEIEELKEK---RDELNEELKELaEKRDELNAQ-------VKELREEAQELREKRDELN 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 673 RKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIESSKCTSIKMAQL--QLENKELESEKE--------QLKKSLE 742
Cdd:COG1340 71 EKVKELKEERDELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERLewRQQTEVLSPEEEkelvekikELEKELE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 743 LMKASFKKSErlevSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVissKRLEQLEKENKLLEQ 822
Cdd:COG1340 151 KAKKALEKNE----KLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELR---KEADELHKEIVEAQE 223
|
250 260
....*....|....*....|..
gi 2024492573 823 ETSQLEKDKKQLEKENKRLRQQ 844
Cdd:COG1340 224 KADELHEEIIELQKELRELRKE 245
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
508-864 |
5.65e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 45.04 E-value: 5.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 508 EELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLREN-----LERQI-----------KLLEQENERSNQTIASLR 571
Cdd:PRK10929 61 KGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPNmstdaLEQEIlqvssqlleksRQAQQEQDRAREISDSLS 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 572 QRSQISAEAQMKEIEKENKIlhESIKETSSKLNKLEFEIKQvrkeMEHYKEKAeRAEELenELHHLEKENellQKKIANL 651
Cdd:PRK10929 141 QLPQQQTEARRQLNEIERRL--QTLGTPNTPLAQAQLTALQ----AESAALKA-LVDEL--ELAQLSANN---RQELARL 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 652 sitceKIEALEKENSDLDIENRKLKKTLDSL--KNLSFQLESLEkensQLDEENLELRRRIesskctsikMAQLQLeNKE 729
Cdd:PRK10929 209 -----RSELAKKRSQQLDAYLQALRNQLNSQrqREAERALESTE----LLAEQSGDLPKSI---------VAQFKI-NRE 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 730 LESEKEQLKKSLELMKASFKK--SERLEVSyQGLDTENQRLQkALENSNKKIQQLEGELQDLE--SENQTLQKNLEELvi 805
Cdd:PRK10929 270 LSQALNQQAQRMDLIASQQRQaaSQTLQVR-QALNTLREQSQ-WLGVSNALGEALRAQVARLPemPKPQQLDTEMAQL-- 345
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 806 sskRLEQLEKENKL--LEQETSQLEKDKKQLEKENKR-----LRQQAEIKDSTLEENNVKINHLEK 864
Cdd:PRK10929 346 ---RVQRLRYEDLLnkQPQLRQIRQADGQPLTAEQNRildaqLRTQRELLNSLLSGGDTLILELTK 408
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
697-847 |
5.79e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 44.82 E-value: 5.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 697 SQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQgldteNQRLQKALENSN 776
Cdd:PRK00409 509 KLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEA-----EKEAQQAIKEAK 583
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 777 KKIQQLEGELQDLESENQTLQKnlEELVISSKRleQLEKENKLLEQETSQLEKDKKQLeKENKRLR-----QQAEI 847
Cdd:PRK00409 584 KEADEIIKELRQLQKGGYASVK--AHELIEARK--RLNKANEKKEKKKKKQKEKQEEL-KVGDEVKylslgQKGEV 654
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
536-682 |
5.94e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 44.85 E-value: 5.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 536 EQLEKKFETLRENLErqiKLLEQENERSNQTIASLRQRsqISA-EAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVR 614
Cdd:COG2433 380 EALEELIEKELPEEE---PEAEREKEHEERELTEEEEE--IRRlEEQVERLEAEVEELEAELEEKDERIERLERELSEAR 454
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 615 KEmehykekAERAEELENELHHLEKENELLQKkianlsitceKIEALEKENSDLDIENRKLKKTLDSL 682
Cdd:COG2433 455 SE-------ERREIRKDREISRLDREIERLER----------ELEEERERIEELKRKLERLKELWKLE 505
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
557-840 |
7.10e-04 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 44.63 E-value: 7.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 557 EQENERSNQTIASLRQRSQISAEAQMKEIEKENKILHESIKETSSKLNKLefeiKQVRKEMEHYKEKA------------ 624
Cdd:pfam05667 196 AQPSSRASVVPSLLERNAAELAAAQEWEEEWNSQGLASRLTPEEYRKRKR----TKLLKRIAEQLRSAalagteatsgas 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 625 ERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLK--------NLSFQLESLEken 696
Cdd:pfam05667 272 RSAQDLAELLSSFSGSSTTDTGLTKGSRFTHTEKLQFTNEAPAATSSPPTKVETEEELQqqreeeleELQEQLEDLE--- 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 697 SQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKasfkkserlevsyqglDTENQ--RLQKALEN 774
Cdd:pfam05667 349 SSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLP----------------DAEENiaKLQALVDA 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 775 SNKKIQQLEG-----------ELQDLESENQT----LQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENK 839
Cdd:pfam05667 413 SAQRLVELAGqwekhrvplieEYRALKEAKSNkedeSQRKLEEIKELREKIKEVAEEAKQKEELYKQLVAEYERLPKDVS 492
|
.
gi 2024492573 840 R 840
Cdd:pfam05667 493 R 493
|
|
| Semenogelin |
pfam05474 |
Semenogelin; This family consists of several mammalian secreted seminal proteins including ... |
604-929 |
7.23e-04 |
|
Semenogelin; This family consists of several mammalian secreted seminal proteins including semenogelin I and II. Freshly ejaculated human semen has the appearance of a loose gel in which the predominant structural protein components are the seminal vesicle secreted semenogelins (Sg). This family also includes seminal vesicle secretory protein 3A from mouse, which has been shown to be involved in the coagulation of semen resulting in the formation of the copulatory plug.
Pssm-ID: 368458 [Multi-domain] Cd Length: 582 Bit Score: 44.48 E-value: 7.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 604 NKLEFEIKQVRKEMEH----YKEKAERAEELENELHHLEKEnelLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTL 679
Cdd:pfam05474 264 NKNQHQTKNLSQDQEHgrkaHKISYPSSRTEERQLHHGEKS---VQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHG 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 680 DSLKNLSFQLESLEKENSQLDEENLElrrriessKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSErleVSYQ 759
Cdd:pfam05474 341 HKENKISYQSSSTEERHLNCGEKGIQ--------KGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENK---ISYQ 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 760 GLDTENQRLQKALENSNKKIQQleGELQdLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENK 839
Cdd:pfam05474 410 SSSTEERRLNSGEKDVQKGVSK--GSIS-IQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNYGGKSTQ 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 840 RLRQQAEIK---------DSTLEENNVKINHLEKEN-KSLFKQIAVYKESCvrlkeLEMENKELVKRASIDKKTLVTLRE 909
Cdd:pfam05474 487 KDVSQSSISfqieklvegKSQIQTPNPNQDQWSGQNaKGKSGQSADSKQDL-----LSHEQKGRYKQESSESHNIVITEH 561
|
330 340
....*....|....*....|
gi 2024492573 910 DLVNEKLKTQQMNNDLEKLS 929
Cdd:pfam05474 562 EVAQDDHLTQQYNEDRNPIS 581
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
459-848 |
8.23e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.12 E-value: 8.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 459 SRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQL 538
Cdd:COG4372 6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 539 EKKFETLRENLERQIKLLEQENERSNQtiaslrqrsqisAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQvrkeme 618
Cdd:COG4372 86 NEQLQAAQAELAQAQEELESLQEEAEE------------LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAE------ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 619 hykeKAERAEELENELHHLEKENELLQKKIANLSITcEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQ 698
Cdd:COG4372 148 ----REEELKELEEQLESLQEELAALEQELQALSEA-EAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 699 LDEENLELRRRIESSkcTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKK 778
Cdd:COG4372 223 AKDSLEAKLGLALSA--LLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLAL 300
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 779 IQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Cdd:COG4372 301 LLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVADG 370
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
387-573 |
8.32e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 8.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 387 KAKLHEMEMERDMDRKKIEELMEENMALEmAQKQSMDESLHLgweLEQINRFTDhSEVSHKSLGLEVTELTSsRLLKLEK 466
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALE-AELDALQERREA---LQRLAEYSW-DEIDVASAEREIAELEA-ELERLDA 682
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 467 EN---QSLLKTVEELRSTMDDsvggNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSK-------DLMKEKE 536
Cdd:COG4913 683 SSddlAALEEQLEELEAELEE----LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARlelrallEERFAAA 758
|
170 180 190
....*....|....*....|....*....|....*..
gi 2024492573 537 QLEKKFETLRENLERQIKLLEQENERSNQTIASLRQR 573
Cdd:COG4913 759 LGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
889-1322 |
8.37e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.56 E-value: 8.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 889 ENKELVKRASIDKKTLVTLREDLVNEKLKtqqmnndLEKLSHELEKIGLNKERLLCDEQSSDDRYKLLESKLESTLKksL 968
Cdd:COG3096 279 ERRELSERALELRRELFGARRQLAEEQYR-------LVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEK--I 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 969 EIKEEKIAALEARLEEStnlnQQLRQELKTVKKNYEALKQRQEEE------------RMVQNPPPRKGEENQSVNKWEKe 1036
Cdd:COG3096 350 ERYQEDLEELTERLEEQ----EEVVEEAAEQLAEAEARLEAAEEEvdslksqladyqQALDVQQTRAIQYQQAVQALEK- 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1037 nqetTRELLKVKDRLIE-VERNNATLQAEKQALKTQLKQLETQnnnlqaqiLALQRQTVSLQEQNTTLQTQNAKlQVENS 1115
Cdd:COG3096 425 ----ARALCGLPDLTPEnAEDYLAAFRAKEQQATEEVLELEQK--------LSVADAARRQFEKAYELVCKIAG-EVERS 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1116 TLNSQSTSLMNQnaqlLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIakhgslksahknle 1195
Cdd:COG3096 492 QAWQTARELLRR----YRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAE-------------- 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1196 vehkDLEDRYSQllkQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDE-------NDRLAH----THDQLLKEN 1264
Cdd:COG3096 554 ----ELEELLAE---LEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARapawlaaQDALERlreqSGEALADSQ 626
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 1265 EVLQTdhknLKTLLNNsklgQTQLEAEFSKLREEYQLLDIkctkisnQCELLSQLKGN 1322
Cdd:COG3096 627 EVTAA----MQQLLER----EREATVERDELAARKQALES-------QIERLSQPGGA 669
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
385-617 |
8.42e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 8.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 385 QLKAKLHEMEMERDMDRKKIEELMEENMALEMAQKQSMDESLHLGWELEQINRFTDHSEVSHKSLGLEVTELtSSRLLKL 464
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL-RAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 465 EKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKkfet 544
Cdd:COG4942 103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA---- 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 545 LRENLERQIKLLEQENERSNQTIASLRQrsqisaeaQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEM 617
Cdd:COG4942 179 LLAELEEERAALEALKAERQKLLARLEK--------ELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
503-802 |
9.57e-04 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 44.07 E-value: 9.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 503 LNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEK---KFETLRENLERQIKLLEQENERSNQT---IASLRQRSQI 576
Cdd:PLN03229 460 LNEMIEKLKKEIDLEYTEAVIAMGLQERLENLREEFSKansQDQLMHPVLMEKIEKLKDEFNKRLSRapnYLSLKYKLDM 539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 577 saeaqMKEIEKEnkilhESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERAEELENELHH--LEKENELLQkkianlsit 654
Cdd:PLN03229 540 -----LNEFSRA-----KALSEKKSKAEKLKAEINKKFKEVMDRPEIKEKMEALKAEVASsgASSGDELDD--------- 600
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 655 cEKIEALEKENSDLDIENRKLkktldsLKNLSFQLESLEKENSQLDEE--NLELRRRIESSKCTSIKMAQLQLENKELES 732
Cdd:PLN03229 601 -DLKEKVEKMKKEIELELAGV------LKSMGLEVIGVTKKNKDTAEQtpPPNLQEKIESLNEEINKKIERVIRSSDLKS 673
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 733 EKEQLKksLELMKASFKKSERLEVSYQGLDTE-NQRLQKALENS--NKKIQQLEGELQDLESENQTLQKNLEE 802
Cdd:PLN03229 674 KIELLK--LEVAKASKTPDVTEKEKIEALEQQiKQKIAEALNSSelKEKFEELEAELAAARETAAESNGSLKN 744
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
458-843 |
1.03e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.17 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 458 SSRLLKLEKEnqsLLKTVEELRStmddsvggNSSRIVKMEKENQRLnkkiEELEKEIVQEKQSLQDNQNLSKDLMKEKEQ 537
Cdd:COG3096 284 SERALELRRE---LFGARRQLAE--------EQYRLVEMARELEEL----SARESDLEQDYQAASDHLNLVQTALRQQEK 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 538 LEKKFETLRENLERqiklLEQENErsnqtIASLRQRSQISAEAQMKEIEKEnkilHESIKetsSKLNKLE--FEIKQVRK 615
Cdd:COG3096 349 IERYQEDLEELTER----LEEQEE-----VVEEAAEQLAEAEARLEAAEEE----VDSLK---SQLADYQqaLDVQQTRA 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 616 EMEHYKEKA-ERAEELeNELHHLEKEN--ELLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFqlesl 692
Cdd:COG3096 413 IQYQQAVQAlEKARAL-CGLPDLTPENaeDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAG----- 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 693 EKENSQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKASFKKS-------ERLEVSYQGLDTEN 765
Cdd:COG3096 487 EVERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIgqqldaaEELEELLAELEAQL 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 766 QRLQKALENSNKKIQQLEGELQDLESENQTLQK-------------NLEELV---------ISSKRLEQLEKENKLlEQE 823
Cdd:COG3096 567 EELEEQAAEAVEQRSELRQQLEQLRARIKELAArapawlaaqdaleRLREQSgealadsqeVTAAMQQLLEREREA-TVE 645
|
410 420
....*....|....*....|
gi 2024492573 824 TSQLEKDKKQLEKENKRLRQ 843
Cdd:COG3096 646 RDELAARKQALESQIERLSQ 665
|
|
| mreC |
TIGR00219 |
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ... |
825-945 |
1.04e-03 |
|
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 129323 [Multi-domain] Cd Length: 283 Bit Score: 43.31 E-value: 1.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 825 SQLEKDKKQLEKENKRLRQQAEIKDSTLEennVKINHLEKENKSLFKQIAVYKescvRLKELEMeNKELVKRASIDKKTL 904
Cdd:TIGR00219 62 SENLKDVNNLEYENYKLRQELLKKNQQLE---ILTQNLKQENVRLRELLNSPL----SSDEYKI-SAEVIYLNYDNYSTQ 133
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2024492573 905 VTLREDLVNEKLKTQQMNNDLEKLSHELEKIGLNKER--LLCD 945
Cdd:TIGR00219 134 VVINKGFNDGVYKDMPVIADGKGLVGKVVSVGSNTSRvlLLTD 176
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
759-934 |
1.14e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.60 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 759 QGLDTENQRLQKALENsnkkiqqLEGELQDLESENQTLQKNLEELvisSKRLEQLEKENKLLEQETSQLEKDKKQLEKen 838
Cdd:COG1579 13 QELDSELDRLEHRLKE-------LPAELAELEDELAALEARLEAA---KTELEDLEKEIKRLELEIEEVEARIKKYEE-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 839 krlrQQAEIKdstleeNNVKINHLEKENKSLFKQIAVYKEscvRLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKT 918
Cdd:COG1579 81 ----QLGNVR------NNKEYEALQKEIESLKRRISDLED---EILELMERIEELEEELAELEAELAELEAELEEKKAEL 147
|
170
....*....|....*.
gi 2024492573 919 QQMNNDLEKLSHELEK 934
Cdd:COG1579 148 DEELAELEAELEELEA 163
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
791-843 |
1.33e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 43.28 E-value: 1.33e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 791 SENQTLQKNLEELVissKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:PRK03992 1 ERLEALEERNSELE---EQIRQLELKLRDLEAENEKLERELERLKSELEKLKS 50
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
882-1013 |
1.46e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.22 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 882 RLKELEMENKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELE----KIGLNKERLlcDEQSSDDRYKLLE 957
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEeveaRIKKYEEQL--GNVRNNKEYEALQ 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 958 SKLEStLKKSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEE 1013
Cdd:COG1579 96 KEIES-LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEE 150
|
|
| Tropomyosin |
pfam00261 |
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ... |
512-715 |
1.58e-03 |
|
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.
Pssm-ID: 459736 [Multi-domain] Cd Length: 235 Bit Score: 42.32 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 512 KEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLR---ENLERQIKLLEQENERSNQTIASlRQRSQISAEAQMKEIEKE 588
Cdd:pfam00261 1 KKMQQIKEELDEAEERLKEAMKKLEEAEKRAEKAEaevAALNRRIQLLEEELERTEERLAE-ALEKLEEAEKAADESERG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 589 NKILHESIKETSSKLNKLEFEIKQVrKEMEH-----YKEKAERAEELENELHHLEKENELLQKKIANL-------SITCE 656
Cdd:pfam00261 80 RKVLENRALKDEEKMEILEAQLKEA-KEIAEeadrkYEEVARKLVVVEGDLERAEERAELAESKIVELeeelkvvGNNLK 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 657 KIEALEKENSDLDIENRKLKKTL-DSLKNLSFQLESLEKENSQLDEENLELRRRIESSKC 715
Cdd:pfam00261 159 SLEASEEKASEREDKYEEQIRFLtEKLKEAETRAEFAERSVQKLEKEVDRLEDELEAEKE 218
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
688-848 |
1.87e-03 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 43.02 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 688 QLESLEKENSQLDEENLELRRRIESskctsIKMAQLQLENKELESEKEQLKKSLELMKASfkksERLEVSYQGLDTENQR 767
Cdd:pfam15709 364 QQEQLERAEKMREELELEQQRRFEE-----IRLRKQRLEEERQRQEEEERKQRLQLQAAQ----ERARQQQEEFRRKLQE 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 768 LQKalensnkkiQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:pfam15709 435 LQR---------KKQQEEAERAEAEKQRQKELEMQLAEEQKRLMEMAEEERLEYQRQKQEAEEKARLEAEERRQKEEEAA 505
|
.
gi 2024492573 848 K 848
Cdd:pfam15709 506 R 506
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
527-810 |
1.89e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 43.08 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 527 LSKDLMKEKEQLEKKFETLRENLERQIKL----LEQENERSNQTIAslrqrsqisaeaqmkeiEKENKI--LHESIKETS 600
Cdd:PHA02562 171 LNKDKIRELNQQIQTLDMKIDHIQQQIKTynknIEEQRKKNGENIA-----------------RKQNKYdeLVEEAKTIK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 601 SKLNKLEFEIKQVRKEMEHYKEkaeraeelenelhHLEKENELLQKKIANLSiTCEKIEALEKEN-------SDLDIENR 673
Cdd:PHA02562 234 AEIEELTDELLNLVMDIEDPSA-------------ALNKLNTAAAKIKSKIE-QFQKVIKMYEKGgvcptctQQISEGPD 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 674 KLKKTLDSLKNLSfqlESLEKENSQLDEENLELrrriesskctsIKMAQLQLENKELESEKEQLKKSLELMKASFKKSER 753
Cdd:PHA02562 300 RITKIKDKLKELQ---HSLEKLDTAIDELEEIM-----------DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKA 365
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024492573 754 levsyqgldtENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRL 810
Cdd:PHA02562 366 ----------AIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLL 412
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
501-745 |
1.90e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.09 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 501 QRLNKKIEElekeivQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQEN---------ERSNQTIASLR 571
Cdd:pfam05667 246 TKLLKRIAE------QLRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGLTKGSRfthteklqfTNEAPAATSSP 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 572 QRSQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMehyKEKAERAEELENELHHLEKENELLQKKIANL 651
Cdd:pfam05667 320 PTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSI---KQVEEELEELKEQNEELEKQYKVKKKTLDLL 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 652 SITCEKIEALEKEnsdldienrkLKKTLDSLKNLSFQ--------LESLEKENSQLDEENLELRRRIESSKCTSIKMAQL 723
Cdd:pfam05667 397 PDAEENIAKLQAL----------VDASAQRLVELAGQwekhrvplIEEYRALKEAKSNKEDESQRKLEEIKELREKIKEV 466
|
250 260
....*....|....*....|..
gi 2024492573 724 QLENKELESEKEQLKKSLELMK 745
Cdd:pfam05667 467 AEEAKQKEELYKQLVAEYERLP 488
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
839-1012 |
2.22e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 839 KRLRQQAEIkDSTLEENNVKINHLEKENKSLFKQIAVYKESCVRLKELEMENKELVKRASIDKKTLVTLREDLvNEKLKT 918
Cdd:COG1579 7 RALLDLQEL-DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKY-EEQLGN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 919 QQMNNDLEKLSHELEKIGLNKERLlcdeqssDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEEstnLNQQLRQELKT 998
Cdd:COG1579 85 VRNNKEYEALQKEIESLKRRISDL-------EDEILELMERIE-ELEEELAELEAELAELEAELEE---KKAELDEELAE 153
|
170
....*....|....
gi 2024492573 999 VKKNYEALKQRQEE 1012
Cdd:COG1579 154 LEAELEELEAEREE 167
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
239-634 |
2.32e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 42.92 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 239 LKHTESKQHLSVElaDAKAKIRRLRQEIEEKNEQFLDYKQELER----VETELRRLQQENKNllSDARSARvyrDELDIL 314
Cdd:pfam06160 112 LLESEEKNREEVE--ELKDKYRELRKTLLANRFSYGPAIDELEKqlaeIEEEFSQFEELTES--GDYLEAR---EVLEKL 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 315 REkaiRVDKLESEVGRYKERLHDME-FYKARVEELMEDNQVMLETKRMFED-QVktlqcrSDKLHVVEKENLQLKAKLHE 392
Cdd:pfam06160 185 EE---ETDALEELMEDIPPLYEELKtELPDQLEELKEGYREMEEEGYALEHlNV------DKEIQQLEEQLEENLALLEN 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 393 MEMER-DMDRKKIEELME---ENMALEMAQKQSMDEslhlgwELEQINRFTDHSEVSHKSLGLEVTELTSS--------- 459
Cdd:pfam06160 256 LELDEaEEALEEIEERIDqlyDLLEKEVDAKKYVEK------NLPEIEDYLEHAEEQNKELKEELERVQQSytlnenele 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 460 RLLKLEKENQSLLKTVEELRSTMDDSVGGNSSrivkMEKENQRLNKKIEELEKEIVQEKQSLQdnqNLSKDLMKEKEQLE 539
Cdd:pfam06160 330 RVRGLEKQLEELEKRYDEIVERLEEKEVAYSE----LQEELEEILEQLEEIEEEQEEFKESLQ---SLRKDELEAREKLD 402
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 540 KkFETLRENLERQIklleqenERSNqtIASLRQrsqiSAEAQMKEIEKEnkilhesIKETSSKLNKLEFEIKQVRKEMEH 619
Cdd:pfam06160 403 E-FKLELREIKRLV-------EKSN--LPGLPE----SYLDYFFDVSDE-------IEDLADELNEVPLNMDEVNRLLDE 461
|
410
....*....|....*
gi 2024492573 620 YKEKAERAEELENEL 634
Cdd:pfam06160 462 AQDDVDTLYEKTEEL 476
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1211-1388 |
2.42e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 2.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1211 QKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKLGQTQLEA 1290
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1291 EFSKLREEYQLLDIKCTKISNQCELLSQLKGN-----------MEEENRHLLDQIQTLML------QNRTLLEQNMESKD 1353
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEdfldavrrlqyLKYLAPARREQAEELRAdlaelaALRAELEAERAELE 177
|
170 180 190
....*....|....*....|....*....|....*
gi 2024492573 1354 LFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYE 1388
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARLEKELAELA 212
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
628-832 |
2.42e-03 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 43.07 E-value: 2.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 628 EELeneLHHLEKENEllqkKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNL--SFQLESLEKENSQLDEENLE 705
Cdd:PTZ00419 797 EEL---YQRLPNYLR----KSESISIAKYPQPNPGWNNEALDEEMKIIMSIVKSIRSLiaTLGIPNKTKPDCYVTAKDAE 869
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 706 LRRRIESSKCTSIKMAQLQLEN--KELESEKEQLKKSL-ELMKASFKKSERLEVSYQgLDTENQRLQKALENSNKKIQQL 782
Cdd:PTZ00419 870 LIELIESAENLISTLAKIGSVSviPPIEEEAEVPKGCGfDVVDNKVIIYLNLDEFID-LKKELAKLEKKLAKLQKSLESY 948
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 783 EGELQDLESEnqtlQKNLEEL-VISSKRLEQLEKENKLLEQETSQLEKDKK 832
Cdd:PTZ00419 949 LKKISIPNYE----DKVPEDVrKLNDEKIDELNEEIKQLEQAIEELKSLLK 995
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
771-874 |
2.50e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 42.76 E-value: 2.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 771 ALENSNKKIQQLEGELQDLESENQTLqknleelviSSKRLEQLEKEnklLEQETSQLEKDKKQLEKENKRLRQQAEIKDS 850
Cdd:COG0542 412 ELDELERRLEQLEIEKEALKKEQDEA---------SFERLAELRDE---LAELEEELEALKARWEAEKELIEEIQELKEE 479
|
90 100
....*....|....*....|....
gi 2024492573 851 tLEENNVKINHLEKENKSLFKQIA 874
Cdd:COG0542 480 -LEQRYGKIPELEKELAELEEELA 502
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
507-1073 |
2.63e-03 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 42.97 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 507 IEELEKEIVQEKQSLQDNQNLSKDLMKEKEQL--EKKFETLRENLERQIKL---LEQENERSNQTIASLRQRSQISAE-- 579
Cdd:pfam15964 123 IHHLEAEVKFCKEELSEMKQRVQVVVLENEKLqqELKSQTQEETLREQTLLdssGNMQNSWCTPEDSRVHQTSKRPAShn 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 580 -------AQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAEraeELENELHHLEK-ENELLQKKIANL 651
Cdd:pfam15964 203 laerlksATTGEDEKWRLELEKLKLLYEAKTEVLESQVKSLRKDLAESQKTCE---DLKERLKHKESlVAASTSSRVGGL 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 652 SITCEKIEA-LEKENSDLDIEN-RKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRI-----ESSKCTSIKMAQLQ 724
Cdd:pfam15964 280 CLKCAQHEAvLAQTHTNVHMQTiERLTKERDDLMSALVSVRSSLAEAQQRESSAYEQVKQAvqmteEANFEKTKALIQCE 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 725 LENKELESEKEQLKKSLELMKAsfKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEElv 804
Cdd:pfam15964 360 QLKSELERQKERLEKELASQQE--KRAQEKEALRKEMKKEREELGATMLALSQNVAQLEAQVEKVTREKNSLVSQLEE-- 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 805 ISSKRLEQLEKENKLLEQETSQLEK---DKKQLEKENKRLR----QQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYK 877
Cdd:pfam15964 436 AQKQLASQEMDVTKVCGEMRYQLNQtkmKKDEAEKEHREYRtktgRQLEIKDQEIEKLGLELSESKQRLEQAQQDAARAR 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 878 ESCVRLKELEMENKELVKRASIDKKTLV-TLREDLVNEKLKTQQMNNDLEKLSHELEKIglnkerllcDEQSSDDRYKLL 956
Cdd:pfam15964 516 EECLKLTELLGESEHQLHLTRLEKESIQqSFSNEAKAQALQAQQREQELTQKMQQMEAQ---------HDKTVNEQYSLL 586
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 957 ESK--LESTLKKSLEIKEEKiaaLEARLEESTNLNQQLRQELKTVKKNYEALKQRQEE--ERMVQNPPPRKgEENQSVNK 1032
Cdd:pfam15964 587 TSQntFIAKLKEECCTLAKK---LEEITQKSRSEVEQLSQEKEYLQDRLEKLQKRNEEleEQCVQHGRMHE-RMKQRLRQ 662
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 2024492573 1033 WEKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLK 1073
Cdd:pfam15964 663 LDKHCQATAQQLVQLLSKQNQLFKERQNLTEEVQSLRSQVP 703
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
682-849 |
2.74e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 41.04 E-value: 2.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 682 LKNLSFQLESLEKENSQLDEENLELRR-------RIESSKCTSIKMAQL-QLENKELESEKEQLKKSLELMKASFKKSER 753
Cdd:pfam15619 13 IKELQNELAELQSKLEELRKENRLLKRlqkrqekALGKYEGTESELPQLiARHNEEVRVLRERLRRLQEKERDLERKLKE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 754 LEVSYQGLDTENQRLQKALENSN--------KKIQQLEGELQDLESENQTLQKNLEELVISSKRleQLEKENKlleqETS 825
Cdd:pfam15619 93 KEAELLRLRDQLKRLEKLSEDKNlaereelqKKLEQLEAKLEDKDEKIQDLERKLELENKSFRR--QLAAEKK----KHK 166
|
170 180
....*....|....*....|....
gi 2024492573 826 QLEKDKKQLEKENKRLRQQAEIKD 849
Cdd:pfam15619 167 EAQEEVKILQEEIERLQQKLKEKE 190
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
240-476 |
2.94e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.80 E-value: 2.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 240 KHTESKQHLSVELADAKAKIR---RLRQEIEEKNEQFldyKQELERVETELRRLQQENKNLLSDARSARVYRDELDILRE 316
Cdd:pfam17380 358 RKRELERIRQEEIAMEISRMReleRLQMERQQKNERV---RQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 317 KAIRVdkLESEVGRYKERLHDMEFYKARVEELMEDNQVMLETKRMFEDQVKTLQCRSDKLH--VVEKENLQLKAKLHEME 394
Cdd:pfam17380 435 REVRR--LEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRrkILEKELEERKQAMIEEE 512
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 395 MERDMDRKKIEElmEENMALEMAQKQSMDESLHLGWELEQINRFTDHSevshkslgLEVTElTSSRLLKLEKENQSLLKT 474
Cdd:pfam17380 513 RKRKLLEKEMEE--RQKAIYEEERRREAEEERRKQQEMEERRRIQEQM--------RKATE-ERSRLEAMEREREMMRQI 581
|
..
gi 2024492573 475 VE 476
Cdd:pfam17380 582 VE 583
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1036-1183 |
3.01e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 3.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1036 ENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL--QVE 1113
Cdd:COG1579 4 EDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYeeQLG 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1114 NSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAK 1183
Cdd:COG1579 84 NVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAE 153
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
256-605 |
3.24e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 42.53 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 256 KAKIRRLRQEIEEKNEQFLDYKQELERVETE-----LRRLQQENKNLLSDARSARVYRDELDILREKAIRVDKLEsevgr 330
Cdd:PLN03229 428 KTPVRELEGEVEKLKEQILKAKESSSKPSELalnemIEKLKKEIDLEYTEAVIAMGLQERLENLREEFSKANSQD----- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 331 ykERLHDMefYKARVEELMEDNQVMLETKRMFEdqvkTLQCRSDKLHVVEKENLQLKAKLHEMEMERDMDrKKIEELMEE 410
Cdd:PLN03229 503 --QLMHPV--LMEKIEKLKDEFNKRLSRAPNYL----SLKYKLDMLNEFSRAKALSEKKSKAEKLKAEIN-KKFKEVMDR 573
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 411 NmalEMAQKqsmdeslhlgweleqINRFTDHSEVSHKSLGLEVTELTSSRLLKLEKENQSLLKTVeeLRStMDDSVGGNS 490
Cdd:PLN03229 574 P---EIKEK---------------MEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELELAGV--LKS-MGLEVIGVT 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 491 SRIVKMEKE--NQRLNKKIEELEKEIVQEKQSLQDNQNLSKDLMKEKEQLEKKFETLRENLERQIKLLEQENErsnQTIA 568
Cdd:PLN03229 633 KKNKDTAEQtpPPNLQEKIESLNEEINKKIERVIRSSDLKSKIELLKLEVAKASKTPDVTEKEKIEALEQQIK---QKIA 709
|
330 340 350
....*....|....*....|....*....|....*..
gi 2024492573 569 SLRQRSQIsaEAQMKEIEKENKILHESIKETSSKLNK 605
Cdd:PLN03229 710 EALNSSEL--KEKFEELEAELAAARETAAESNGSLKN 744
|
|
| dnaK |
CHL00094 |
heat shock protein 70 |
891-1002 |
3.38e-03 |
|
heat shock protein 70
Pssm-ID: 214360 [Multi-domain] Cd Length: 621 Bit Score: 42.41 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 891 KELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKlsHELEKIGL-NKERLLCDEqsSDDRYKLLESKLESTLKKSLE 969
Cdd:CHL00094 486 KGTGKEQSITIQGASTLPKDEVERMVKEAEKNAAEDK--EKREKIDLkNQAESLCYQ--AEKQLKELKDKISEEKKEKIE 561
|
90 100 110
....*....|....*....|....*....|....*
gi 2024492573 970 --IKEEKIAALEARLEESTNLNQQLRQELKTVKKN 1002
Cdd:CHL00094 562 nlIKKLRQALQNDNYESIKSLLEELQKALMEIGKE 596
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
521-660 |
3.38e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 41.05 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 521 LQDNQNLSKDLMKEKEQLEKKFETLrenlERQIKLLEQENERSNQTIASLRQRSQIsAEAQMKEIEKENKILhesiKETS 600
Cdd:pfam13851 21 TRNNLELIKSLKEEIAELKKKEERN----EKLMSEIQQENKRLTEPLQKAQEEVEE-LRKQLENYEKDKQSL----KNLK 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 601 SKLNKLEFEIKQVRKEMEHYKEKAERAEELENELH------------HLEKENELLQKKIANLSITCEKIEA 660
Cdd:pfam13851 92 ARLKVLEKELKDLKWEHEVLEQRFEKVERERDELYdkfeaaiqdvqqKTGLKNLLLEKKLQALGETLEKKEA 163
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
675-1138 |
3.66e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 42.25 E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 675 LKKTLDSLKNLSFQLESLEKENSQLDEeNLELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKSLELMKasfKKSERL 754
Cdd:COG5185 119 LISLLYLYKSEIVALKDELIKVEKLDE-IADIEASYGEVETGIIKDIFGKLTQELNQNLKKLEIFGLTLGL---LKGISE 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 755 EVSYQGLDTENQRLQKALENSNkkiqqlegelqdleSENQTLQKNLEELVIsskrleqlEKENKLLEQETSQLEKDKKQL 834
Cdd:COG5185 195 LKKAEPSGTVNSIKESETGNLG--------------SESTLLEKAKEIINI--------EEALKGFQDPESELEDLAQTS 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 835 EKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKESCV-RLKELEMEN-----KELVKRASIDKKTLVTLR 908
Cdd:COG5185 253 DKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAeYTKSIDIKKateslEEQLAAAEAEQELEESKR 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 909 EDLVNEKLKTQQMNNDLEKLSHELEKIGLNKERLLCDEQSSDDRYKL--LESKLESTLKKSLEI-------KEEKIAALE 979
Cdd:COG5185 333 ETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSSEELdsFKDTIESTKESLDEIpqnqrgyAQEILATLE 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 980 ARLEESTNLNQQLRQELKTVKKNYEAlKQRQEEERMVQNPPPRKGEENQSVNKWEKENQETTRELLKVKDRLievernNA 1059
Cdd:COG5185 413 DTLKAADRQIEELQRQIEQATSSNEE-VSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSKKEDL------NE 485
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1060 TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQ-NTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSAL 1138
Cdd:COG5185 486 ELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESlKDFMRARGYAHILALENLIPASELIQASNAKTDGQAANL 565
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
976-1204 |
3.74e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 976 AALEARLEESTNLNQqLRQELKTVKKNYEALKQ----RQEEERMVQnpppRKGEENQSVNKWEKENQETTRELLKvkDRL 1051
Cdd:COG4913 225 EAADALVEHFDDLER-AHEALEDAREQIELLEPirelAERYAAARE----RLAELEYLRAALRLWFAQRRLELLE--AEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1052 IEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVslqeqnTTLQTQNAKLQVEnstLNSQSTSLMNQNAQL 1131
Cdd:COG4913 298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRL------EQLEREIERLERE---LEERERRRARLEALL 368
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024492573 1132 liqqSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEyesLIAKHGSLKSAHKNLEVEHKDLEDR 1204
Cdd:COG4913 369 ----AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAE---AEAALRDLRRELRELEAEIASLERR 434
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
790-850 |
3.99e-03 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 42.05 E-value: 3.99e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 790 ESENQTLQknlEELVISSKRLEQLEKENKLLEQETSQLEKDKKQ-LEKENKRLRQQAEIKDS 850
Cdd:pfam12004 391 EQEISKLK---ERLRVSNRKLEEYERRLLAQEEQTQKLLLEYQArLEDSEERLRRQQEEKDS 449
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
1147-1220 |
4.02e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 41.25 E-value: 4.02e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024492573 1147 KELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGSLKSAHKNLEVEHKDLEDRYSQLlkqKVQLEELEK 1220
Cdd:COG4026 135 EELLELKEKIDEIAKEKEKLTKENEELESELEELREEYKKLREENSILEEEFDNIKSEYSDL---KSRFEELLK 205
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
600-742 |
4.04e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 4.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 600 SSKLNKLEFE----IKQVRKEMEHYKEKAERaeELENELHHL--EKENELLQKKianlsitcEKIEALEKensdldienr 673
Cdd:PRK12704 30 EAKIKEAEEEakriLEEAKKEAEAIKKEALL--EAKEEIHKLrnEFEKELRERR--------NELQKLEK---------- 89
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 674 klkKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIEsskctsikmaQLQLENKELESEKEQLKKSLE 742
Cdd:PRK12704 90 ---RLLQKEENLDRKLELLEKREEELEKKEKELEQKQQ----------ELEKKEEELEELIEEQLQELE 145
|
|
| Atg16_CCD |
cd22887 |
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1048-1117 |
4.05e-03 |
|
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins.
Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 38.32 E-value: 4.05e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1048 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1117
Cdd:cd22887 3 ESELQELEKRLAELEAELASLEEEIKDLEEELKEKNKANEILNDELIALQIENNLLEEKLRKLQEENDEL 72
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1062-1298 |
4.14e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 4.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1062 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSALENE 1141
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1142 KEgvlkeledlkslydsllkdheklehlheRQASEYESLIA---KHGSLKSAHKNLEVEHKDLEDRYSQLLKQ-----KV 1213
Cdd:COG4942 99 LE----------------------------AQKEELAELLRalyRLGRQPPLALLLSPEDFLDAVRRLQYLKYlaparRE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1214 QLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNNSKLGQTQLEAEFS 1293
Cdd:COG4942 151 QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
|
....*
gi 2024492573 1294 KLREE 1298
Cdd:COG4942 231 RLEAE 235
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
542-695 |
4.54e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.12 E-value: 4.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 542 FET-----LRENL-ERQIKLLEQENERSNQTIASLrqrsqisaEAQMKEIEKENKilhesiketssklnKLEFEIKQVRK 615
Cdd:PRK00409 491 FEIakrlgLPENIiEEAKKLIGEDKEKLNELIASL--------EELERELEQKAE--------------EAEALLKEAEK 548
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 616 EMEHYKEKAER-AEELENELHHLEKEnelLQKKIANLSITCEKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEK 694
Cdd:PRK00409 549 LKEELEEKKEKlQEEEDKLLEEAEKE---AQQAIKEAKKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEK 625
|
.
gi 2024492573 695 E 695
Cdd:PRK00409 626 K 626
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
594-737 |
4.64e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 41.99 E-value: 4.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 594 ESIKETSSKLNKLEFEIKQVRKEMEhyKEKAERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKENSDLDIENR 673
Cdd:COG0542 411 EELDELERRLEQLEIEKEALKKEQD--EASFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELEQRYGKIP 488
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 674 KLKKTLDSLKNLSFQLESLEKEnsQLDEENlelrrrIES--SKCTSIKMAQLqlenkeLESEKEQL 737
Cdd:COG0542 489 ELEKELAELEEELAELAPLLRE--EVTEED------IAEvvSRWTGIPVGKL------LEGEREKL 540
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
550-664 |
4.67e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.69 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 550 ERQIKLLEQENERsnqtiasLRQRSQISAEAQMKEI-----EKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKA 624
Cdd:PRK12704 30 EAKIKEAEEEAKR-------ILEEAKKEAEAIKKEAlleakEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKL 102
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2024492573 625 ERAEELENELHHLEKENELLQKKIANLSITCEKIEALEKE 664
Cdd:PRK12704 103 ELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQ 142
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
251-607 |
4.71e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.80 E-value: 4.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 251 ELADAKAKIRRLRQEIEEKNEQFLDYKQELERVETELRRLQQENKnllsdaRSARVYRDELDILREKAIRVDKLESEVGR 330
Cdd:pfam07888 42 ERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELK------EELRQSREKHEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 331 YKERLHDM-EFYKARVEELMEDNQVMLETKRMFEDQVKTLQCRSDKLHV----VEKENLQLKAKLHEMEMERDMDRKKIE 405
Cdd:pfam07888 116 EKDALLAQrAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAqrkeEEAERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 406 ELMEENMALEMAQKQSMDESLHLGWELEQINRFTDHSEVSHKslglevtELTSSRLLKLEKEnqsllKTVEELRSTMDDS 485
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLE-------ELRSLQERLNASE-----RKVEGLGEELSSM 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 486 VGGNSSRIVKMEK---ENQRLNKKIEELEKEI-------VQEKQSLQDNQNLSKD-LMKEKEQLEKKFETLREN-LERQI 553
Cdd:pfam07888 264 AAQRDRTQAELHQarlQAAQLTLQLADASLALregrarwAQERETLQQSAEADKDrIEKLSAELQRLEERLQEErMEREK 343
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2024492573 554 KLLEQENER-SNQTIASLRQRSQISAEAQMKEIEKENKILHESIKETSSKLNKLE 607
Cdd:pfam07888 344 LEVELGREKdCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
566-742 |
5.05e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.62 E-value: 5.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 566 TIASLRQRSQISAEAQmkeiekenKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAERA--EELENELHHLEKENEL 643
Cdd:PRK12705 21 LVVLLKKRQRLAKEAE--------RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRerEELQREEERLVQKEEQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 644 LQKKianlsitCEKIEALEKENSDLDienRKLKKTLDSLKNLSFQLESLEKENSQLDEEnlELRRRIesskctsikmaqL 723
Cdd:PRK12705 93 LDAR-------AEKLDNLENQLEERE---KALSARELELEELEKQLDNELYRVAGLTPE--QARKLL------------L 148
|
170
....*....|....*....
gi 2024492573 724 QLENKELESEKEQLKKSLE 742
Cdd:PRK12705 149 KLLDAELEEEKAQRVKKIE 167
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
1059-1140 |
5.38e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 41.37 E-value: 5.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1059 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKL--QVENSTLNSQST-----SLMNQNAQL 1131
Cdd:COG3524 224 ATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALEKQ---IAAERARLtgASGGDSLASLLAeyerlELEREFAEK 300
|
90
....*....|.
gi 2024492573 1132 LIQQS--ALEN 1140
Cdd:COG3524 301 AYTSAlaALEQ 311
|
|
| Jnk-SapK_ap_N |
pfam09744 |
JNK_SAPK-associated protein-1; This is the N-terminal 200 residues of a set of proteins ... |
741-844 |
5.41e-03 |
|
JNK_SAPK-associated protein-1; This is the N-terminal 200 residues of a set of proteins conserved from yeasts to humans. Most of the proteins in this entry have an RhoGEF pfam00621 domain at their C-terminal end.
Pssm-ID: 462875 [Multi-domain] Cd Length: 150 Bit Score: 39.52 E-value: 5.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 741 LELMKASFKKSERLEVSYQGLDTENQRLQKALEnsnKKIQQLEGELQDLESENQTLQKNLEELVissKRLEQLEKENKLL 820
Cdd:pfam09744 35 LELLESLASRNQEHNVELEELREDNEQLETQYE---REKALRKRAEEELEEIEDQWEQETKDLL---SQVESLEEENRRL 108
|
90 100
....*....|....*....|....*
gi 2024492573 821 EQE-TSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam09744 109 EADhVSRLEEKEAELKKEYSKLHER 133
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1145-1380 |
5.65e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 5.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1145 VLKELEDLKSLYDSLLKDHEKLEHLherqaseyESLIAKHGSLKSAHKnlEVEHKDLEDRYSQLLKQKVQLEELEKVLKT 1224
Cdd:COG4913 230 LVEHFDDLERAHEALEDAREQIELL--------EPIRELAERYAAARE--RLAELEYLRAALRLWFAQRRLELLEAELEE 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1225 EQEKMLQQNEKHETVAAEYKKLRDENDRLahthdqllkENEVLQTDHKNLKtllnnsklgqtQLEAEFSKLREEYQLLDI 1304
Cdd:COG4913 300 LRAELARLEAELERLEARLDALREELDEL---------EAQIRGNGGDRLE-----------QLEREIERLERELEERER 359
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024492573 1305 KCTKISNQCELLsqlkgnmEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1380
Cdd:COG4913 360 RRARLEALLAAL-------GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEI 428
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1034-1360 |
6.08e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.04 E-value: 6.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1034 EKENQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVE 1113
Cdd:COG4372 44 QEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1114 NSTLNSQSTSLMNQNAQLLIQQSALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEyesliakhGSLKSAHKN 1193
Cdd:COG4372 124 RQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALD--------ELLKEANRN 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1194 LEVEHKDLEDRYSQLLKQKVQLEELEKVLKTEQEKMLQQNEKHETVAAEYKKLRDENDRlahtHDQLLKENEVLQTDHKN 1273
Cdd:COG4372 196 AEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEE----VILKEIEELELAILVEK 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1274 LKTLLNNSKLGQTQLEAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1353
Cdd:COG4372 272 DTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLL 351
|
....*..
gi 2024492573 1354 LFHVEQR 1360
Cdd:COG4372 352 DNDVLEL 358
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
556-823 |
6.13e-03 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 41.06 E-value: 6.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 556 LEQENERSNQTIASLRQRSQiSAEAQMKEI-EKENKILHESIKETSSKLNKLEFEIKQVRKEMEHYKEKAE----RAEEL 630
Cdd:pfam00038 23 LEQQNKLLETKISELRQKKG-AEPSRLYSLyEKEIEDLRRQLDTLTVERARLQLELDNLRLAAEDFRQKYEdelnLRTSA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 631 ENELH--------------HLEKENELLQKKIANL-SITCEKIEALEKENSDLDIE---NRKLKKTLDS-LKNLSFQLES 691
Cdd:pfam00038 102 ENDLVglrkdldeatlarvDLEAKIESLKEELAFLkKNHEEEVRELQAQVSDTQVNvemDAARKLDLTSaLAEIRAQYEE 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 692 LEKEN---------SQLDEENLELRRRIESSKCTSIKMAQLQLENKELESEKEQLKKslelMKASFKKSERlevsyqglD 762
Cdd:pfam00038 182 IAAKNreeaeewyqSKLEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKK----QKASLERQLA--------E 249
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 763 TEnQRLQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQ-LEKENKLLEQE 823
Cdd:pfam00038 250 TE-ERYELQLADYQELISELEAELQETRQEMARQLREYQELLNVKLALDIeIATYRKLLEGE 310
|
|
| ATG17_like |
pfam04108 |
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ... |
531-792 |
6.52e-03 |
|
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ATG17 and ATG11, conserved across eukaryotes. ATG17 forms a complex with ATG29 and ATG31, critical for both PAS (preautophagosomal structure) formation and autophagy. Together with ATG13, it is required for ATG1 kinase activation. ATG11 is a scaffold protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway during starvation and to recruit ATG proteins to the pre-autophagosome. It is also required for ATG1 kinase activation. In many eukaryotes, ATG11 (the orthologue in mammals is RB1-inducible coiled-coil protein 1 (RB1CC1) and in S. pombe is Taz1-interacting factor 1 (taf1)) is essential for bulk autophagy, except in S.cerevisiae. ATG17 and ATG11 are large similar proteins, both predicted to be almost entirely helical, containing conserved coiled-coil regions and lack obvious functional motifs.
Pssm-ID: 427715 [Multi-domain] Cd Length: 360 Bit Score: 41.22 E-value: 6.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 531 LMKEKEQLEKKFETLRENLERQIKLLEQENERSNQTIASLRQRSQISAEAQ-------------MKEIEKENKILHESIK 597
Cdd:pfam04108 47 LEKVREGLEKVLNELKKDFKQLLKDLDAALERLEETLDKLRNTPVEPALPPgeekqktlldfidEDSVEILRDALKELID 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 598 ETSSKLNKLEFEIKQVRKEMEHYK---EKAERAEELENELHHLEKENELLQKKIANL--SIT-----------------C 655
Cdd:pfam04108 127 ELQAAQESLDSDLKRFDDDLRDLQkelESLSSPSESISLIPTLLKELESLEEEMASLleSLTnhydqcvtavklteggrA 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 656 EKIEALEKENSDLDIENRKLKKTLDSLKNLSFQLESLEKENSQLDEENLELRRRIES--SKCTSIKMAQLQLENKeLESE 733
Cdd:pfam04108 207 EMLEVLENDARELDDVVPELQDRLDEMENNYERLQKLLEQKNSLIDELLSALQLIAEiqSRLPEYLAALKEFEER-WEEE 285
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024492573 734 KEQLKKSLELMKASFKKSERLEVSYQGLDTENQRLQKALENSNKKIQQLEGELQDLESE 792
Cdd:pfam04108 286 KETIEDYLSELEDLREFYEGFPSAYGSLLLEVERRREWAEKMKKILRKLAEELDRLQEE 344
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
662-1273 |
6.57e-03 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 41.74 E-value: 6.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 662 EKENSDLDIENRKLKKTLDSLKNLsfqLESLEKENSQLDEENlELRRRIESSKcTSIKMAQLQLENKELESEK-----EQ 736
Cdd:PTZ00440 2002 EKAETLNNLKLNKIKEDFNSYKNL---LDELEKSVKTLKASE-NIKKIVENKK-TSIDAINTNIEDIEKEIESinpslDE 2076
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 737 LKKSLELMKASFKKSERLEVSYQ-GLDTENQRLQKalENSNKKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEK 815
Cdd:PTZ00440 2077 LLKKGHKIEISRYTSIIDNVQTKiSNDSKNINDIE--KKAQIYLAYIKNNYNSIKKDISTLNEYFDEKQVSNYILTNIDK 2154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 816 ENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKD-STLEENNVKI----NHLEKENKSLFKqiaVYKES-CVRLKELEME 889
Cdd:PTZ00440 2155 ANKLSSELSEAVTNSEEIIENIKKEIIEINENTEmNTLENTADKLkelyENLKKKKNIINN---IYKKInFIKLQEIENS 2231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 890 NKELVKRASIDKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELekIGLNKERLLCDEQSSDDRYKLLES------KLEST 963
Cdd:PTZ00440 2232 SEKYNDISKLFNNVVETQKKKLLDNKNKINNIKDKINDKEKEL--INVDSSFTLESIKTFNEIYDDIKSnigdlyKLEDT 2309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 964 LK---KSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSVNKWEKENqET 1040
Cdd:PTZ00440 2310 NNdelKKVKLYIENITHLLNRINTLINDLDNYQDENYGKDKNIELNNENNSYIIKTKEKINNLKEEFSKLLKNIKRN-NT 2388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1041 TRELLKVKDRLIEVERNNATLQA---EKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1117
Cdd:PTZ00440 2389 LCNNNNIKDFISNIGKSVETIKQrfsSNLPEKEKLHQIEENLNEIKNIMNETKRISNVDAFTNKILQDIDNEKNKENNNM 2468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1118 NSQSTSLMNQNAQLLIQQ-----SALENEKEGVLKELEDLKSLYDSLLKDHEKLEHLHERQASEYESLIAKHGS----LK 1188
Cdd:PTZ00440 2469 NAEKIDDLIENVTSHNEKikselLIINDALRRVKEKKDEMNKLFNSLTENNNNNNNSAKNIVDNSTYIINELEShvskLN 2548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1189 SAHKNLEVEHKDLEDRYSQLLKQKVQLE---ELEKVLKTEQEKmlQQNEKHETVAAEYKKLRDENDRlahTHDQLLKENE 1265
Cdd:PTZ00440 2549 ELLSYIDNEIKELENEKLKLLEKAKIEEsrkERERIESETQED--NTDEEQINRQQQERLQKEEEQK---AYSQERLNRE 2623
|
....*...
gi 2024492573 1266 VLQTDHKN 1273
Cdd:PTZ00440 2624 VSGTDDTN 2631
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
728-872 |
7.18e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.89 E-value: 7.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 728 KELESEKEQLKKSLE----LMKASFKKSERLEVSYQGLDTENQRLQKALENSNK----------KIQQLEGELQDLESEN 793
Cdd:pfam13851 29 KSLKEEIAELKKKEErnekLMSEIQQENKRLTEPLQKAQEEVEELRKQLENYEKdkqslknlkaRLKVLEKELKDLKWEH 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 794 QTLQKNLEELVISSKRLEQ------------LEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINH 861
Cdd:pfam13851 109 EVLEQRFEKVERERDELYDkfeaaiqdvqqkTGLKNLLLEKKLQALGETLEKKEAQLNEVLAAANLDPDALQAVTEKLED 188
|
170
....*....|.
gi 2024492573 862 LEKENKSLFKQ 872
Cdd:pfam13851 189 VLESKNQLIKD 199
|
|
| PLN02372 |
PLN02372 |
violaxanthin de-epoxidase |
502-588 |
7.18e-03 |
|
violaxanthin de-epoxidase
Pssm-ID: 215212 [Multi-domain] Cd Length: 455 Bit Score: 40.98 E-value: 7.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 502 RLNKKIEELEKEIVQEKQSLQdnqnlsKDLMKEKEQLEKKFETL--RENLERQIKLLEQENERSNQTIASLRQRSQISAE 579
Cdd:PLN02372 365 RLEKDVEEGEKTIVKEARQIE------EELEKEVEKLGKEEESLfkRVALEEGLKELEQDEENFLKELSKEEKELLEKLK 438
|
....*....
gi 2024492573 580 AQMKEIEKE 588
Cdd:PLN02372 439 MEASEVEKL 447
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
451-683 |
7.31e-03 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 41.01 E-value: 7.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 451 LEVTEL-----TS---SRLLKLEKEnqsllKTVEELRSTMDDSVGGNSSRIVKMEKENQRLNKKIEELEKeivqeKQSLQ 522
Cdd:smart00434 234 IVITELpyqvnTAdliEKIAELVKD-----KKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYK-----LTKLQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 523 DNQNLSK---DLMKEKEQLEKKfETLRENLERQIKLLEQeneRSNQTIASLRQRSQISAEAQMKEIEKENKILhESIKet 599
Cdd:smart00434 304 TTFSINMlalFDNGRPKKYNLK-EILKEFLDHRLEVYTR---RKEYLLGKLEAERLHILEGLFIALSIIDEII-VLIR-- 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 600 ssKLNKLEFEIKQvrKEMEHYKEKAERAEelenelhhlekenELLQKKIAnlSITCEKIEALEKENSDLDIENRKLKKTL 679
Cdd:smart00434 377 --SSKDLAKEAKE--KLMERFELSEIQAD-------------AILDMRLR--RLTKLEVEKLEKELKELEKEIEDLEKIL 437
|
....
gi 2024492573 680 DSLK 683
Cdd:smart00434 438 ASEE 441
|
|
| TPR_MLP1_2 |
pfam07926 |
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ... |
966-1106 |
7.55e-03 |
|
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.
Pssm-ID: 462316 [Multi-domain] Cd Length: 129 Bit Score: 38.39 E-value: 7.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 966 KSLEIKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMvqnpppRKGEENQSVNKWEKENQETTRELL 1045
Cdd:pfam07926 1 AELSSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELV------LHAEDIKALQALREELNELKAEIA 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 1046 KVKDrliEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAlqrqtvsLQEQNTTLQTQ 1106
Cdd:pfam07926 75 ELKA---EAESAKAELEESEESWEEQKKELEKELSELEKRIED-------LNEQNKLLHDQ 125
|
|
| Uso1_p115_C |
pfam04871 |
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular ... |
777-854 |
7.77e-03 |
|
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerization, and a short C-terminal acidic region. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the golgi stack. This family consists of the acidic C-terminus, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another.
Pssm-ID: 461461 [Multi-domain] Cd Length: 121 Bit Score: 38.53 E-value: 7.77e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024492573 777 KKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEE 854
Cdd:pfam04871 1 AKKSELESEASSLKNENTELKAELQELSKQYNSLEQKESQAKELEAEVKKLEEALKKLKAELSEEKQKEKEKQSELDD 78
|
|
| Prefoldin_2 |
pfam01920 |
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996. |
777-872 |
7.77e-03 |
|
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.
Pssm-ID: 396482 [Multi-domain] Cd Length: 102 Bit Score: 37.97 E-value: 7.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 777 KKIQQLEGELQDLESENQTLQKNLEELVISSKRLEQLEKENKL------------LEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam01920 2 NKFQQLQQQLQLLAQQIKQLETQLKELELALEELELLDEDTKVykligdvlvkqdKEEVKEQLEERKETLEKEIKTLEKQ 81
|
90 100
....*....|....*....|....*...
gi 2024492573 845 AEIKDSTLEEnnvkinhLEKENKSLFKQ 872
Cdd:pfam01920 82 LEKLEKELEE-------LKEELYKKFGQ 102
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
450-933 |
7.77e-03 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 41.21 E-value: 7.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 450 GLEVTELTSSRLLKLEKENQSLLKTVEELRSTMDDSVGGNSSRIVKMEK-ENQRLNKKIEELEKEIvqEKQSLQDNQNLS 528
Cdd:COG5244 84 GLVCESKGMDKDGEIKQENHEDRIHFEESKIRRLEETIEALKSTEKEEIvELRRENEELDKINLSL--RERISSEEPELN 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 529 KDLMKEKEQLEKKFetLRENLERQIKLLEQENERS--NQTIASLRQRSQISAEAQ--MKEIEKENKILHESIKETSSKLN 604
Cdd:COG5244 162 KDGSKLSYDELKEF--VEESRVQVYDMVELVSDISetLNRNGSIQRSSVRECERSniHDVLFLVNGILDGVIDELNGELE 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 605 KLEFEIKQVRKEMEHYKEKAERAEELENELHHLEKENELLQ------KKIANLSITCEKI-------------EALEKEN 665
Cdd:COG5244 240 RLRRQLVSLMSSHGIEVEENSRLKATLEKFQSLELKVNTLQeelyqnKLLKKFYQIYEPFaqaalssqlqylaEVIESEN 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 666 SDLdIENRKLKKTLDSLKNLSFQLESLEKENSQ-LDEENLE---------------LRRRIESSKCTSIKMAQLQLENKE 729
Cdd:COG5244 320 FGK-LENIEIHIILKVLSSISYALHIYTIKNTPdHLETTLQcfvniapismwlsefLQRKFSSKQETAFSICQFLEDNKD 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 730 LESEKEQLKKSLELMKASFKKSERLEVSYQGLDTENqrlQKALENSNKKIQQLEGELQDLESENQTLQKNLEELVIS--- 806
Cdd:COG5244 399 VTLILKILHPILETTVPKLLAFLRTNSNFNDNDTLC---LIGSLYEIARIDKLIGKEEISKQDNRLFLYPSCDITLSsil 475
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 807 ----SKRLEQLEKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKescvr 882
Cdd:COG5244 476 tilfSDKLEVFFQGIESLLENITIFPEQPSQQTSDSENIKENSLLSDRLNEENIRLKEVLVQKENMLTEETKIKI----- 550
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 2024492573 883 LKELEMENKELvkrasidKKTLVTLREDLVNEKLKTQQMNNDLEKLSHELE 933
Cdd:COG5244 551 IIGRDLERKTL-------EENIKTLKVELNNKNNKLKEENFNLVNRLKNME 594
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
814-1031 |
7.85e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.97 E-value: 7.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 814 EKENKLLEQETSQLEKDKKQLEKENKRLRQQAEIKDSTLEENNVKINHLEKENKSLFKQIAVYKEscvRLKELEMENKEL 893
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEA---EIEERREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 894 VKRASIDKKTLVTLredlvnEKLKTQQMNNDLEKLSHELEKIGLNKERLLcDEQSSD-DRYKLLESKLE---STLKKSLE 969
Cdd:COG3883 92 ARALYRSGGSVSYL------DVLLGSESFSDFLDRLSALSKIADADADLL-EELKADkAELEAKKAELEaklAELEALKA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024492573 970 IKEEKIAALEARLEESTNLNQQLRQELKTVKKNYEALKQRQEEERMVQNPPPRKGEENQSVN 1031
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAA 226
|
|
| ADIP |
pfam11559 |
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ... |
546-626 |
8.01e-03 |
|
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.
Pssm-ID: 463295 [Multi-domain] Cd Length: 151 Bit Score: 38.84 E-value: 8.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 546 RENLERQIKLLEQENERSNQTIASLR------QRSQISAEAQMKEIEKENKILHESIKETSSKLNKLEFEIKQVRKEMEH 619
Cdd:pfam11559 54 RESLNETIRTLEAEIERLQSKIERLKtqledlERELALLQAKERQLEKKLKTLEQKLKNEKEELQRLKNALQQIKTQFAH 133
|
....*..
gi 2024492573 620 YKEKAER 626
Cdd:pfam11559 134 EVKKRDR 140
|
|
| TMCO5 |
pfam14992 |
TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing ... |
579-746 |
9.45e-03 |
|
TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing proteins 5A and 5B.
Pssm-ID: 464427 [Multi-domain] Cd Length: 278 Bit Score: 40.09 E-value: 9.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 579 EAQMKEIEKENKILHESIKETSSKLNKLEFEIKQV--------RKEMEHYKEKAERA-EELENELHHLEKENELLQKKIA 649
Cdd:pfam14992 9 EKDLQRLDEANQVLLLKIQEKEEEIQSLEREITLTrslaedeeREELNFTIMEKEDAlQELELETAKLEKKNEILVKSVM 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 650 NLSitcEKIEALEKENSDLDIENrkLKKTLDSLKNLSFQLESL----EKENSQLDEENLELRRRIEsSKCTSIKMAQLQL 725
Cdd:pfam14992 89 ELQ---RKLSRKSDKNTGLEQET--LKQMLEELKVKLQQSEEScadqEKELAKVESDYQSVHQLCE-DQALCIKKYQEIL 162
|
170 180
....*....|....*....|.
gi 2024492573 726 enKELESEKEQLKKSLELMKA 746
Cdd:pfam14992 163 --RKMEEEKETRLLEKEVSKA 181
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
1205-1340 |
9.57e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 40.39 E-value: 9.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024492573 1205 YSQLLKQKVQLEELEKVLKTEQEKMlqqNEKHETVAAEYKKLRDENDRLAHTHDQLLKENEVLQTDHKNLKTLLNN-SKL 1283
Cdd:smart00787 125 FARLEAKKMWYEWRMKLLEGLKEGL---DENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDElEDC 201
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024492573 1284 GQTQLEAEFSKLREEYQLLDIKCTKISNQCELLSQLKGNMEEENrhllDQIQTLMLQ 1340
Cdd:smart00787 202 DPTELDRAKEKLKKLLQEIMIKVKKLEELEEELQELESKIEDLT----NKKSELNTE 254
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
810-851 |
9.77e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 39.96 E-value: 9.77e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 2024492573 810 LEQLEKENKLLEQETSQLEKDK---KQLEKENKRLRQQAEIKDST 851
Cdd:PRK13922 71 LFDLREENEELKKELLELESRLqelEQLEAENARLRELLNLKESL 115
|
|
| |
