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Conserved domains on  [gi|2024450121|ref|XP_040535871|]
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solute carrier family 12 member 1 isoform X1 [Gallus gallus]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
101-1129 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1442.21  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  101 NTMDPVPKIDYYRNTGSVSGNKLNRPSLLEIHEQLAKNIAVSTGSVERVANG-ESTAGEET--AASKEEEKKTGFVKFGW 177
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGqGMKEHEEAedAEGTKEKPPAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  178 VKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLGVIIILLatmvtsitglstsaiatngfvrgglgiivialSVVVTTLTG 257
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILL--------------------------------CCCVTTITG 128
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  258 ISMSAICTNGVVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVELLKESDT-IMVDESNDIRIIGT 336
Cdd:TIGR00930  129 LSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLDLLRENGSkIMVDPINDIRIYGT 208
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  337 ITVVCLLGISVAGMEWEAKAQVILLIVLLIAIANFFIGTVIPTNNeKKARGFFNYQASIFAENFGPDFRSGEG-FFSVFA 415
Cdd:TIGR00930  209 VTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFD-KPAKGFFGLGNEIFSENFIPGIPGPEGgFFSLFG 287
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  416 IFFPAATGILAGANISGDLKDPQGAIPKGTMLAILITTVAYIGVAVCAASCVVRDATGNVNDTVIPgmsCNGSSACnlgy 495
Cdd:TIGR00930  288 IFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC---- 360
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  496 dFSRCRSQPCDYGLMNNFQVMSMVSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNVYKGLHFFAKGYGKNNEPI 575
Cdd:TIGR00930  361 -FSECAHNTCSYGLMNNLQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPL 439
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  576 RGYVLTFVIAMAFILIAQLNTIAPIISNFFLASYALINFSCFHASYAKSPGWRPAFRYYNMWISLFGALLCCGVMFVINW 655
Cdd:TIGR00930  440 RAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISW 519
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  656 WAALITYVIELFLYIYVTYKKPEVNWGSSTQALCYIKALDSALALTTVEDHVKNFRPQCIVLTGAPMIRPALLDITHSFT 735
Cdd:TIGR00930  520 WAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFT 599
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  736 KNNGLCICCEVYTGPRKLCVKEMNSGMAKKQAWLTKNKRKAFYAAVAADSFRDGVKSLLQASGLGRMKPNTLVIGFKKDW 815
Cdd:TIGR00930  600 KGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDW 679
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  816 RNAAVTQVENYVGVIHDAFDFELGTIIVRIGQGFDISqVLQVQEelekleqerlaleatikENEFDEEKSGIcgffrkar 895
Cdd:TIGR00930  680 RQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLPIS-VLQVQE-----------------ELENDCSEDSI-------- 733
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  896 klnitkheAKNESTINTVQSMHvgefnqklLEASTQFKKKQGKGTIDIWWLFDDGGLTILIPYILTIRKKWKNCKLRIFT 975
Cdd:TIGR00930  734 --------ELNDGKISTQPDMH--------LEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFV 797
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  976 GG-KVNRIEEEKLVMASLLSKFRIKFADINIICDINMKPNKESWKFFEEMIEPYRLRESCKDITTAE-KLKRETPWKITD 1053
Cdd:TIGR00930  798 GAqKDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRLHKTEKDREAKDpKMTWTKPWKITD 877
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024450121 1054 AELEAFKEKSYRQVRLNELLQEHSRAANLIVLSLPVARKGVVSDYLYMAWLEILSKNLPPILMVRGNHKNVLTFYS 1129
Cdd:TIGR00930  878 AELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
101-1129 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1442.21  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  101 NTMDPVPKIDYYRNTGSVSGNKLNRPSLLEIHEQLAKNIAVSTGSVERVANG-ESTAGEET--AASKEEEKKTGFVKFGW 177
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGqGMKEHEEAedAEGTKEKPPAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  178 VKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLGVIIILLatmvtsitglstsaiatngfvrgglgiivialSVVVTTLTG 257
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILL--------------------------------CCCVTTITG 128
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  258 ISMSAICTNGVVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVELLKESDT-IMVDESNDIRIIGT 336
Cdd:TIGR00930  129 LSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLDLLRENGSkIMVDPINDIRIYGT 208
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  337 ITVVCLLGISVAGMEWEAKAQVILLIVLLIAIANFFIGTVIPTNNeKKARGFFNYQASIFAENFGPDFRSGEG-FFSVFA 415
Cdd:TIGR00930  209 VTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFD-KPAKGFFGLGNEIFSENFIPGIPGPEGgFFSLFG 287
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  416 IFFPAATGILAGANISGDLKDPQGAIPKGTMLAILITTVAYIGVAVCAASCVVRDATGNVNDTVIPgmsCNGSSACnlgy 495
Cdd:TIGR00930  288 IFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC---- 360
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  496 dFSRCRSQPCDYGLMNNFQVMSMVSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNVYKGLHFFAKGYGKNNEPI 575
Cdd:TIGR00930  361 -FSECAHNTCSYGLMNNLQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPL 439
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  576 RGYVLTFVIAMAFILIAQLNTIAPIISNFFLASYALINFSCFHASYAKSPGWRPAFRYYNMWISLFGALLCCGVMFVINW 655
Cdd:TIGR00930  440 RAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISW 519
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  656 WAALITYVIELFLYIYVTYKKPEVNWGSSTQALCYIKALDSALALTTVEDHVKNFRPQCIVLTGAPMIRPALLDITHSFT 735
Cdd:TIGR00930  520 WAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFT 599
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  736 KNNGLCICCEVYTGPRKLCVKEMNSGMAKKQAWLTKNKRKAFYAAVAADSFRDGVKSLLQASGLGRMKPNTLVIGFKKDW 815
Cdd:TIGR00930  600 KGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDW 679
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  816 RNAAVTQVENYVGVIHDAFDFELGTIIVRIGQGFDISqVLQVQEelekleqerlaleatikENEFDEEKSGIcgffrkar 895
Cdd:TIGR00930  680 RQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLPIS-VLQVQE-----------------ELENDCSEDSI-------- 733
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  896 klnitkheAKNESTINTVQSMHvgefnqklLEASTQFKKKQGKGTIDIWWLFDDGGLTILIPYILTIRKKWKNCKLRIFT 975
Cdd:TIGR00930  734 --------ELNDGKISTQPDMH--------LEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFV 797
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  976 GG-KVNRIEEEKLVMASLLSKFRIKFADINIICDINMKPNKESWKFFEEMIEPYRLRESCKDITTAE-KLKRETPWKITD 1053
Cdd:TIGR00930  798 GAqKDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRLHKTEKDREAKDpKMTWTKPWKITD 877
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024450121 1054 AELEAFKEKSYRQVRLNELLQEHSRAANLIVLSLPVARKGVVSDYLYMAWLEILSKNLPPILMVRGNHKNVLTFYS 1129
Cdd:TIGR00930  878 AELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
SLC12 pfam03522
Solute carrier family 12;
724-1129 0e+00

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 589.59  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  724 RPALLDITHSFTKNNGLCICCEVYTGPRKLCVKEMNsgMAKKQAWLTKNKRKAFYAAVAADSFRDGVKSLLQASGLGRMK 803
Cdd:pfam03522    1 RPALVDFAHLITKNVSLMICGHVVKGRLSQKLRSEL--QKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLK 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  804 PNTLVIGFKKDWRNAAVTQVENYVGVIHDAFDFELGTIIVRIGQGFDISQVLQVQEELEKleqeRLALEATIKENEFDEE 883
Cdd:pfam03522   79 PNILLMGYKSDWRTCDKEELEEYFNVIHDAFDLQYAVAILRLPEGLDVSHLLQDQDTEEL----GLGDETNSSYAEQSSE 154
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  884 KSGICGFFRKARKLNITKHEAK---NESTINTVQSMHVGEFNQKL------------------LEASTQFKKKQGKGTID 942
Cdd:pfam03522  155 EQSTSNSKQDDDKSKLSKKDSNlslSPDKSTKNPSGKDSSKSDKLkkkspsiilrtasnekeiLNNITQFQKKQKKGTID 234
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  943 IWWLFDDGGLTILIPYILTIRKKWKNCKLRIFTGG-KVNRIEEEKLVMASLLSKFRIKFADINIICDINMKPNKESWKFF 1021
Cdd:pfam03522  235 VWWLYDDGGLTLLLPYILSTRSKWSDCKLRVFALGnRKDELEEEQRNMASLLSKFRIDYSDLTVIPDITKKPKKETKKFF 314
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121 1022 EEMIEPYRLRESCKDittaeklkRETPWKITDAELEAFKEKSYRQVRLNELLQEHSRAANLIVLSLPVARKGVVSDYLYM 1101
Cdd:pfam03522  315 DELIEPFRLHEDDKE--------EESAEKITDSELEALKEKTNRQLRLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYM 386
                          410       420
                   ....*....|....*....|....*...
gi 2024450121 1102 AWLEILSKNLPPILMVRGNHKNVLTFYS 1129
Cdd:pfam03522  387 AWLETLTKDLPPFLLVRGNQTSVLTFYS 414
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
209-679 1.54e-40

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 155.83  E-value: 1.54e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  209 LGVIIILLATMVTSITGLSTSAIATNGfvrGGLGIIVIALSVVVTTLTGISMSAICTNgVVRGGGAYYLISRSLGPEFGG 288
Cdd:COG0531     16 FDLVALGVGAIIGAGIFVLPGLAAGLA---GPAAILAWLIAGLLALLVALSYAELASA-FPRAGGAYTYARRALGPLLGF 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  289 SIGLIFAFANAVAVAMYVVGFAETVVELLKESDTImvdesndirIIGTITVVCLLGISVAGMEWEAKAQVILLIVLLiai 368
Cdd:COG0531     92 LAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSV---------LIALVLILLLTLLNLRGVKESAKVNNILTVLKL--- 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  369 anFFIGTVIptnnekkARGFFNYQASIFAeNFGPDFRSGEGFFSVFAIFFPAATGILAGANISGDLKDPQGAIPKGTMLA 448
Cdd:COG0531    160 --LVLLLFI-------VVGLFAFDPANFT-PFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILS 229
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  449 ILITTVAYIGVAVCAASCVVRDATGNVNDTVipgmscngssacnlgydfsrcrsqpcdyglmnnFQVMSMVSG--FGPLI 526
Cdd:COG0531    230 LLIVGVLYILVSLALTGVVPYDELAASGAPL---------------------------------ADAAEAVFGpwGAILI 276
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  527 TAGIFSATLSSALASLVSAPKVFQALCKDNVykgL-HFFAKGYGKNNEPIRGYVLTFVIAMAFILI--AQLNTIAPIISN 603
Cdd:COG0531    277 ALGALLSLLGALNASILGASRLLYAMARDGL---LpKVFAKVHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASV 353
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024450121  604 FFLASYALINFSCFHASYaKSPGWRPAFRYYNMWISLFGALLCCGVMFVINWWA---ALITYVIELFLYIYVTYKKPEV 679
Cdd:COG0531    354 GVLLAYLLVALAVIVLRR-RRPDLPRPFRVPLPLIPILGILLCLFLLYLLGPGAlliGLVLLAIGLLLYLLYRRRHPKL 431
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
101-1129 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1442.21  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  101 NTMDPVPKIDYYRNTGSVSGNKLNRPSLLEIHEQLAKNIAVSTGSVERVANG-ESTAGEET--AASKEEEKKTGFVKFGW 177
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGqGMKEHEEAedAEGTKEKPPAGAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  178 VKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLGVIIILLatmvtsitglstsaiatngfvrgglgiivialSVVVTTLTG 257
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILL--------------------------------CCCVTTITG 128
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  258 ISMSAICTNGVVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVELLKESDT-IMVDESNDIRIIGT 336
Cdd:TIGR00930  129 LSMSAIATNGVVKGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVLDLLRENGSkIMVDPINDIRIYGT 208
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  337 ITVVCLLGISVAGMEWEAKAQVILLIVLLIAIANFFIGTVIPTNNeKKARGFFNYQASIFAENFGPDFRSGEG-FFSVFA 415
Cdd:TIGR00930  209 VTVVVLLGISFAGMEWENKAQVLFLVIVLLSILNIFVGTIIPAFD-KPAKGFFGLGNEIFSENFIPGIPGPEGgFFSLFG 287
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  416 IFFPAATGILAGANISGDLKDPQGAIPKGTMLAILITTVAYIGVAVCAASCVVRDATGNVNDTVIPgmsCNGSSACnlgy 495
Cdd:TIGR00930  288 IFFPSVTGILAGANISGDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC---- 360
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  496 dFSRCRSQPCDYGLMNNFQVMSMVSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNVYKGLHFFAKGYGKNNEPI 575
Cdd:TIGR00930  361 -FSECAHNTCSYGLMNNLQVMSLVSPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPL 439
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  576 RGYVLTFVIAMAFILIAQLNTIAPIISNFFLASYALINFSCFHASYAKSPGWRPAFRYYNMWISLFGALLCCGVMFVINW 655
Cdd:TIGR00930  440 RAYLLTAFIAEGFILIAELNTIAPIISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISW 519
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  656 WAALITYVIELFLYIYVTYKKPEVNWGSSTQALCYIKALDSALALTTVEDHVKNFRPQCIVLTGAPMIRPALLDITHSFT 735
Cdd:TIGR00930  520 WAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFT 599
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  736 KNNGLCICCEVYTGPRKLCVKEMNSGMAKKQAWLTKNKRKAFYAAVAADSFRDGVKSLLQASGLGRMKPNTLVIGFKKDW 815
Cdd:TIGR00930  600 KGKGLMICGSVIQGPRLECVKEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDW 679
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  816 RNAAVTQVENYVGVIHDAFDFELGTIIVRIGQGFDISqVLQVQEelekleqerlaleatikENEFDEEKSGIcgffrkar 895
Cdd:TIGR00930  680 RQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLPIS-VLQVQE-----------------ELENDCSEDSI-------- 733
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  896 klnitkheAKNESTINTVQSMHvgefnqklLEASTQFKKKQGKGTIDIWWLFDDGGLTILIPYILTIRKKWKNCKLRIFT 975
Cdd:TIGR00930  734 --------ELNDGKISTQPDMH--------LEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFV 797
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  976 GG-KVNRIEEEKLVMASLLSKFRIKFADINIICDINMKPNKESWKFFEEMIEPYRLRESCKDITTAE-KLKRETPWKITD 1053
Cdd:TIGR00930  798 GAqKDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRLHKTEKDREAKDpKMTWTKPWKITD 877
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024450121 1054 AELEAFKEKSYRQVRLNELLQEHSRAANLIVLSLPVARKGVVSDYLYMAWLEILSKNLPPILMVRGNHKNVLTFYS 1129
Cdd:TIGR00930  878 AELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLPPVLLVRGNHRNVLTFYS 953
SLC12 pfam03522
Solute carrier family 12;
724-1129 0e+00

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 589.59  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  724 RPALLDITHSFTKNNGLCICCEVYTGPRKLCVKEMNsgMAKKQAWLTKNKRKAFYAAVAADSFRDGVKSLLQASGLGRMK 803
Cdd:pfam03522    1 RPALVDFAHLITKNVSLMICGHVVKGRLSQKLRSEL--QKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLK 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  804 PNTLVIGFKKDWRNAAVTQVENYVGVIHDAFDFELGTIIVRIGQGFDISQVLQVQEELEKleqeRLALEATIKENEFDEE 883
Cdd:pfam03522   79 PNILLMGYKSDWRTCDKEELEEYFNVIHDAFDLQYAVAILRLPEGLDVSHLLQDQDTEEL----GLGDETNSSYAEQSSE 154
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  884 KSGICGFFRKARKLNITKHEAK---NESTINTVQSMHVGEFNQKL------------------LEASTQFKKKQGKGTID 942
Cdd:pfam03522  155 EQSTSNSKQDDDKSKLSKKDSNlslSPDKSTKNPSGKDSSKSDKLkkkspsiilrtasnekeiLNNITQFQKKQKKGTID 234
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  943 IWWLFDDGGLTILIPYILTIRKKWKNCKLRIFTGG-KVNRIEEEKLVMASLLSKFRIKFADINIICDINMKPNKESWKFF 1021
Cdd:pfam03522  235 VWWLYDDGGLTLLLPYILSTRSKWSDCKLRVFALGnRKDELEEEQRNMASLLSKFRIDYSDLTVIPDITKKPKKETKKFF 314
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121 1022 EEMIEPYRLRESCKDittaeklkRETPWKITDAELEAFKEKSYRQVRLNELLQEHSRAANLIVLSLPVARKGVVSDYLYM 1101
Cdd:pfam03522  315 DELIEPFRLHEDDKE--------EESAEKITDSELEALKEKTNRQLRLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYM 386
                          410       420
                   ....*....|....*....|....*...
gi 2024450121 1102 AWLEILSKNLPPILMVRGNHKNVLTFYS 1129
Cdd:pfam03522  387 AWLETLTKDLPPFLLVRGNQTSVLTFYS 414
AA_permease pfam00324
Amino acid permease;
180-715 6.68e-120

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 377.82  E-value: 6.68e-120
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  180 GVLVRCMLNIWGVMLFIRLSWIVGQAGIGLGVIIILLATMVTSITGLSTSAIATNGFVrgglgiivialsvvvttltgis 259
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV---------------------- 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  260 msaictngvvrGGGAYYLISRSLGPEFGGSIGL------IFAFANAVAVAMYVVGFAETVVELLKESDTimvdesndiri 333
Cdd:pfam00324   59 -----------SGGFYTYASRFLGPSLGFATGWnywlswITVLALELTAASILIQFWELVPDIPYLWVW----------- 116
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  334 iGTITVVCLLGISVAGMEWEAKAQVILLIVLLIAIANFFIGTVIPTNNEK--KARGFFNYQASIFAENFGPDFrsGEGFF 411
Cdd:pfam00324  117 -GAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIILLSGGNpnDGAIFRYLGDNGGKNNFPPGF--GKGFI 193
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  412 SVFAIFFPAATGILAGANISGDLKDPQGAIPKGTMLAILITTVAYIGVAVCAASCVVRDATGNVNDTVIPgmscngssac 491
Cdd:pfam00324  194 SVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASA---------- 263
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  492 nlgydfsrcrsqpcdYGLMNNFQVMSMVSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNVYKglhFFAKGYGKN 571
Cdd:pfam00324  264 ---------------ASPFVIFFKFLGISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAP---KFLKKVDKR 325
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  572 NEPIRGYVLTFVIAMAFILIAQLNTIapIISNFFLASYALINFSCFHASYAKSPGWRPAFRYYNMWISLFGALLCCGVMF 651
Cdd:pfam00324  326 GVPLRAILVSMVISLLALLLASLNPA--IVFNFLLAISGLSGLIVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLG 403
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024450121  652 VINWWAALITYVIELFLYIYVTYKKPEVNWGSSTQALCYIKALDSALALTTVEDHVKNFRPQCI 715
Cdd:pfam00324  404 VILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
209-679 1.54e-40

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 155.83  E-value: 1.54e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  209 LGVIIILLATMVTSITGLSTSAIATNGfvrGGLGIIVIALSVVVTTLTGISMSAICTNgVVRGGGAYYLISRSLGPEFGG 288
Cdd:COG0531     16 FDLVALGVGAIIGAGIFVLPGLAAGLA---GPAAILAWLIAGLLALLVALSYAELASA-FPRAGGAYTYARRALGPLLGF 91
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  289 SIGLIFAFANAVAVAMYVVGFAETVVELLKESDTImvdesndirIIGTITVVCLLGISVAGMEWEAKAQVILLIVLLiai 368
Cdd:COG0531     92 LAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSV---------LIALVLILLLTLLNLRGVKESAKVNNILTVLKL--- 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  369 anFFIGTVIptnnekkARGFFNYQASIFAeNFGPDFRSGEGFFSVFAIFFPAATGILAGANISGDLKDPQGAIPKGTMLA 448
Cdd:COG0531    160 --LVLLLFI-------VVGLFAFDPANFT-PFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILS 229
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  449 ILITTVAYIGVAVCAASCVVRDATGNVNDTVipgmscngssacnlgydfsrcrsqpcdyglmnnFQVMSMVSG--FGPLI 526
Cdd:COG0531    230 LLIVGVLYILVSLALTGVVPYDELAASGAPL---------------------------------ADAAEAVFGpwGAILI 276
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  527 TAGIFSATLSSALASLVSAPKVFQALCKDNVykgL-HFFAKGYGKNNEPIRGYVLTFVIAMAFILI--AQLNTIAPIISN 603
Cdd:COG0531    277 ALGALLSLLGALNASILGASRLLYAMARDGL---LpKVFAKVHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASV 353
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024450121  604 FFLASYALINFSCFHASYaKSPGWRPAFRYYNMWISLFGALLCCGVMFVINWWA---ALITYVIELFLYIYVTYKKPEV 679
Cdd:COG0531    354 GVLLAYLLVALAVIVLRR-RRPDLPRPFRVPLPLIPILGILLCLFLLYLLGPGAlliGLVLLAIGLLLYLLYRRRHPKL 431
AA_permease_N pfam08403
Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid ...
87-154 4.68e-34

Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid permease domain (pfam00324) in metazoan Na-K-Cl cotransporters.


Pssm-ID: 429977  Cd Length: 70  Bit Score: 124.86  E-value: 4.68e-34
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121   87 DTHNKMYYLQTFGHNTMDPVPKIDYYRNTGSVSGNKLNRPSLLEIHEQLAKN--IAVSTGSVERVANGES 154
Cdd:pfam08403    1 DTHGSTYYLQTFGHNTLDAVPRIDFYRNTGSVSGVKKSRPSLAELHSQLKKNsaLAVAEGSVDGVENGDG 70
AA_permease_2 pfam13520
Amino acid permease;
195-658 1.35e-15

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 80.43  E-value: 1.35e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  195 FIRLSWIVGQAGIGLGVIiillatmVTSITGLSTSAIATNGFVrgGLGIIVIALSVVVTTLTGISMSAictngvvrgGGA 274
Cdd:pfam13520    3 LLSAFALVIGSVIGSGIF-------VAPLVASGGPALIVWGWI--AAIIFSLAVGLVYAELSSALPRS---------GGI 64
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  275 YYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVELLKESdtiMVDESNDIRIIGTITVVCLLGISVAGMEWEA 354
Cdd:pfam13520   65 YVYLENAFGKFVAFLAGWSNWFAYVLGLASSASVAASYLLSALGPD---LVPTTWLTYGIAIAILIIFAIINIRGVRESA 141
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  355 KAQVILLIVLLIAIANFFIGTVIPTnnekKARGFFNYqASIFAENFGPDFrsGEGFFSVFAIFFPAATGILAGANISGDl 434
Cdd:pfam13520  142 KIQNILGILKLLLPLILIIILGLVT----ADGGGFNL-LSGEWHTFFPDG--WPGVFAGFLGVLWSFTGFESAANVSEE- 213
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  435 kDPQGAIPKGTMLAILITTVAYIGVAVCAASCVVRDATGNVNDTVIPGmscngssacnlgydfsrcrsqpcdyGLMNNFQ 514
Cdd:pfam13520  214 -VKKRNVPKAIFIGVIIVGVLYILVNIAFFGVVPDDEIALSSGLGQVA-------------------------ALLFQAV 267
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  515 VMSMVSGFgplITAGIFSATLSSALASLVSAPKVFQALCKDNVYKGLHFFAKgYGKNNEPIRGYVLTFVIAMAFILI--- 591
Cdd:pfam13520  268 GGKWGAII---VVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAK-VNKFGSPIRAIILTAILSLILLLLfll 343
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024450121  592 --AQLNTIAPIISNFFLASYALINFSCFHASYaKSPGWRpafRYYNMWISLFGALLCCGVMFVINWWAA 658
Cdd:pfam13520  344 spAAYNALLSLSAYGYLLSYLLPIIGLLILRK-KRPDLG---RIPGRWPVAIFGILFSLFLIVALFFPP 408
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
409-612 4.84e-03

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 40.95  E-value: 4.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  409 GFFSVFAIFFPAATGILAGANISGDLKDPQGAIPKGTMLAILITTVAYIGVAvcAASCVvrdatgnvndtVIPGMSCNGS 488
Cdd:TIGR00906  232 GVLSGAATCFFAFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMS--AALTL-----------MMPYYLLDPD 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024450121  489 SAcnLGYDFSRCRSQPCDYglmnnfqvmsmvsgfgpLITAGIFSATLSSALASLVSAPKVFQALCKDNVYKGlhFFAKGY 568
Cdd:TIGR00906  299 AP--FPVAFEYVGWDPAKY-----------------IVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLFK--WLAQIN 357
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 2024450121  569 GKNNEPIRGYVLTFVIAMAFILIAQLNTIAPIISNFFLASYALI 612
Cdd:TIGR00906  358 SKTKTPINATVVSGAIAALMAFLFDLKALVDLLSIGTLLAYSLV 401
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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