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Conserved domains on  [gi|2024460238|ref|XP_040540459|]
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CAP-Gly domain-containing linker protein 1 isoform X9 [Gallus gallus]

Protein Classification

CAP-Gly domain-containing linker protein; CAP-Gly domain-containing protein( domain architecture ID 13652022)

CAP-Gly domain-containing linker protein similar to mammalian CLIP-170 and CLIP-115, which are homodimers and act as general promoters of microtubule growth| CAP (cytoskeleton-associated protein)-Gly domain-containing protein similar to Schizosaccharomyces pombe Tip elongation protein 1 that has a role in stabilizing and targeting the growing tips of the microtubules along the long axis of the cell, directing them to the ends of the cell

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.13e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.13e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.26e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.26e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 670-1494 9.98e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.23  E-value: 9.98e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  670 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 730
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  731 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 799
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  800 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 879
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  880 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 953
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  954 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1026
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1027 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1090
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1091 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1154
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1155 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1234
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1235 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1314
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1315 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1388
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1389 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1465
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024460238 1466 KKSLENAFSDMKREQELDFSAKRLLVQEN 1494
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1320-2036 2.89e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 2.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1320 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1391
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1392 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1471
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1472 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1551
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1552 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKN 1631
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1632 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1711
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1712 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1774
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1775 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1820
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1821 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1900
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1901 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1980
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1981 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2036
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 353-983 3.91e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 3.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  353 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlemeakmdQLRAMVEAADREKVELLNQL 432
Cdd:COG1196    217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELE------------------ELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  433 EEEKRKVEDLQFRVEEESITKGDLERKRQisedpenvatvSEKSRIMELERDLALRVKEVAELRGRLEsskhiddvdtsl 512
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIA-----------RLEERRRELEERLEELEEELAELEEELE------------ 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  513 SLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSK 592
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE--EA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  593 LESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEK 672
Cdd:COG1196    412 LLERLERLEEELEELEEA------LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  673 EQTLENLKAKLESVEDQHLVEMEDTLNKLQEA-------EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAL 745
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglagAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  746 QKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS----LEKELQL 821
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAalrrAVTLAGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  822 LKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 901
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  902 SSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK----------AEQSQQETlkthQEELKKMQ 971
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgpvnllAIEEYEEL----EERYDFLS 801

                          650
                   ....*....|..
gi 2024460238  972 DQLTDMKKQMET 983
Cdd:COG1196    802 EQREDLEEARET 813
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2160-2176 7.75e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.75e-08
                           10
                   ....*....|....*..
gi 2024460238 2160 RPYCDTCEMFGHWTADC 2176
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2120-2137 5.65e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.65e-04
                           10
                   ....*....|....*...
gi 2024460238 2120 RLFCDICGCFDlHDTEDC 2137
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.13e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.13e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.26e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.26e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 217-282 2.62e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.52  E-value: 2.62e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238   217 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPRYGLFAPVHKVT 282
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 61-126 2.89e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 2.89e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238    61 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLRGIFTRPSKLS 126
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 670-1494 9.98e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.23  E-value: 9.98e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  670 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 730
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  731 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 799
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  800 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 879
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  880 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 953
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  954 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1026
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1027 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1090
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1091 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1154
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1155 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1234
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1235 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1314
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1315 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1388
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1389 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1465
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024460238 1466 KKSLENAFSDMKREQELDFSAKRLLVQEN 1494
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1320-2036 2.89e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 2.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1320 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1391
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1392 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1471
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1472 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1551
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1552 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKN 1631
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1632 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1711
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1712 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1774
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1775 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1820
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1821 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1900
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1901 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1980
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1981 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2036
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 816-1666 1.34e-16

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 86.56  E-value: 1.34e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  816 EKELQLLKEKFTSAVDGAENAQRAMQETINKLN-QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEN 894
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKlKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  895 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQD 972
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  973 QLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLS 1052
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1053 SVLASARKEIELMSDKMRDLISEKETLaQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1132
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1133 EAAEAKSRQESTEKvaliSEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREEL 1212
Cdd:pfam02463  488 LLLSRQKLEERSQK----ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1213 EHYQKLLEENDR-------VIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCL 1285
Cdd:pfam02463  564 QKLVRALTELPLgarklrlLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1286 LQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSS 1365
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1366 REASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHN 1445
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1446 EALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQ-ELIACRSD 1524
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLkEEELEEQK 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1525 LSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARVLDKE 1604
Cdd:pfam02463  884 LKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238 1605 SFLLERMELQNNigfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKET 1666
Cdd:pfam02463  964 RLLLAKEELGKV---NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1032-1676 1.63e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.63e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1032 DELETQAEELKKQAEQA---KSLSSVLAsaRKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQ 1108
Cdd:COG1196    196 GELERQLEPLERQAEKAeryRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1109 QDREELwtkNEELNsenkkilkqkeaaeaksrqestekvALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1188
Cdd:COG1196    274 LELEEL---ELELE-------------------------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1189 KELQankdavdvacQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKD 1268
Cdd:COG1196    326 AELE----------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1269 LDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDL 1348
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1349 KASLSSLSNFLEEMKSSREASNSEkihLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELN 1428
Cdd:COG1196    476 EAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1429 LEKESVFSKSLQFEKHNEA--LLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEE 1506
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1507 ELKKKnlenqeliacrsdlsdLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVE 1586
Cdd:COG1196    633 EAALR----------------RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1587 NMKENLTVEKKARVLDKEsfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEkmiLYKET 1666
Cdd:COG1196    697 EALLAEEEEERELAEAEE----ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE---LEREL 769

                          650
                   ....*....|
gi 2024460238 1667 EQLASKIEQL 1676
Cdd:COG1196    770 ERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 530-1330 7.02e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.87  E-value: 7.02e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  530 KEHQREMSSLKEKFESSEEALRKEiktlsasnerMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKV 609
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTE----------TGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKR 1153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  610 SFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKakllevTEEKEQTLENLKAKLESVEDQ 689
Cdd:PTZ00121  1154 VEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAAR------KAEEERKAEEARKAEDAKKAE 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  690 HLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQ 769
Cdd:PTZ00121  1228 AVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  770 IQNLETEKvggssKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLN- 848
Cdd:PTZ00121  1308 KKKAEEAK-----KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADa 1382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  849 -QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndiaEIMKS-SGDSSAQLMKMNDELRLKERQLEQ 926
Cdd:PTZ00121  1383 aKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE----EKKKAdEAKKKAEEAKKADEAKKKAEEAKK 1458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  927 IQLELTKANEKavqlqKNVEQTAQKAEQSQQ-ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK 1005
Cdd:PTZ00121  1459 AEEAKKKAEEA-----KKADEAKKKAEEAKKaDEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1006 HDADIKGFKQNLLDAEEALKAAQKKNDELETQAEElKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNT 1085
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA 1612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1086 LKLEKESLLSQHL----EMESKILLVQQDREELWTKNEELN--SENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSE 1159
Cdd:PTZ00121  1613 KKAEEAKIKAEELkkaeEEKKKVEQLKKKEAEEKKKAEELKkaEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1160 IETAQADLLKITQENDALRSSESTLLQQL-KELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQS 1238
Cdd:PTZ00121  1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELkKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEE 1772

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1239 syddlARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQ 1318
Cdd:PTZ00121  1773 -----IRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEAD 1847

                          810
                   ....*....|..
gi 2024460238 1319 ALKLRKDEMQTE 1330
Cdd:PTZ00121  1848 AFEKHKFNKNNE 1859
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 353-983 3.91e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 3.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  353 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlemeakmdQLRAMVEAADREKVELLNQL 432
Cdd:COG1196    217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELE------------------ELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  433 EEEKRKVEDLQFRVEEESITKGDLERKRQisedpenvatvSEKSRIMELERDLALRVKEVAELRGRLEsskhiddvdtsl 512
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIA-----------RLEERRRELEERLEELEEELAELEEELE------------ 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  513 SLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSK 592
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE--EA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  593 LESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEK 672
Cdd:COG1196    412 LLERLERLEEELEELEEA------LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  673 EQTLENLKAKLESVEDQHLVEMEDTLNKLQEA-------EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAL 745
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglagAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  746 QKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS----LEKELQL 821
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAalrrAVTLAGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  822 LKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 901
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  902 SSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK----------AEQSQQETlkthQEELKKMQ 971
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgpvnllAIEEYEEL----EERYDFLS 801

                          650
                   ....*....|..
gi 2024460238  972 DQLTDMKKQMET 983
Cdd:COG1196    802 EQREDLEEARET 813
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 215-275 5.79e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 71.25  E-value: 5.79e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024460238  215 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLF 275
Cdd:COG5244      4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 358-971 7.60e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 71.30  E-value: 7.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  358 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALVRDG-------HDRHVLEMEAKMDQLRAMVEAADREKV 426
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  427 ELLNQLEEekrkvedlQFRVEEESITKGDLERKrQISEDPENVatvseKSRIMELERDLALRVKEVAELRgrlESSKHID 506
Cdd:pfam15921  342 DKIEELEK--------QLVLANSELTEARTERD-QFSQESGNL-----DDQLQKLLADLHKREKELSLEK---EQNKRLW 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  507 DVDTSLSLlqEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENeSLKTKLDHANKENSDVI 586
Cdd:pfam15921  405 DRDTGNSI--TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS-SLTAQLESTKEMLRKVV 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  587 ELWKSKlESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVkldyenemsNLKLKQenekSQHLKEiealkakll 666
Cdd:pfam15921  482 EELTAK-KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV---------DLKLQE----LQHLKN--------- 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  667 evteeKEQTLENLKAKLESVedqhlvemedtlnKLQEAEiKVKELDVLQAKCNEQTKLIGsltQQIRASEEKLLDLAALQ 746
Cdd:pfam15921  539 -----EGDHLRNVQTECEAL-------------KLQMAE-KDKVIEILRQQIENMTQLVG---QHGRTAGAMQVEKAQLE 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  747 KANSEGKLEIQKLS-------EQLQAAEKQIQNLETEKV----GGSSKVSNLTKELQGKEQKLLDLEKNLSAVNqvkdSL 815
Cdd:pfam15921  597 KEINDRRLELQEFKilkdkkdAKIRELEARVSDLELEKVklvnAGSERLRAVKDIKQERDQLLNEVKTSRNELN----SL 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  816 EKELQLLKEKFTSAVDGAE-----------NAQRAMQETINKLNQKE--------------EQFALMSSELEQLKSNLTV 870
Cdd:pfam15921  673 SEDYEVLKRNFRNKSEEMEtttnklkmqlkSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQSKIQF 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  871 METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLmkmnDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ 950
Cdd:pfam15921  753 LEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          650       660
                   ....*....|....*....|.
gi 2024460238  951 KAEQSQQETLKTHQEELKKMQ 971
Cdd:pfam15921  829 RQEQESVRLKLQHTLDVKELQ 849
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
342-901 6.16e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.17  E-value: 6.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  342 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVrDGHDRHVLEMEAKMDQLRAMVEAA 421
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  422 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENvaTVSEKSRIMELERDLALRVKEVAELRGRLES 501
Cdd:PRK03918   258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE--YLDELREIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  502 SKhiddvdtslsllQEISSLQEKMaaagKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKE 581
Cdd:PRK03918   336 KE------------ERLEELKKKL----KELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKA 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  582 NSDvIELWKSKLESAIASHQQAMEELKVSFNKgvgaqtAEFAELKTQMEKVKLDYENEmsnlklkqENEKSQHLKEIEAL 661
Cdd:PRK03918   400 KEE-IEEEISKITARIGELKKEIKELKKAIEE------LKKAKGKCPVCGRELTEEHR--------KELLEEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  662 KAKLLEvTEEKEQTLENLKAKLESV--EDQHLVEMEDTLNKLQEAEIKVKELDV--LQAKCNEQTKL---IGSLTQQIRA 734
Cdd:PRK03918   465 EKELKE-IEEKERKLRKELRELEKVlkKESELIKLKELAEQLKELEEKLKKYNLeeLEKKAEEYEKLkekLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  735 SEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVggsSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS 814
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV---EELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  815 LEKELQLLKEKFtSAVDGAENAQRAMQETINKLNQK--EEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKL 892
Cdd:PRK03918   621 LKKLEEELDKAF-EELAETEKRLEELRKELEELEKKysEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699


                   ....*....
gi 2024460238  893 ENDIAEIMK 901
Cdd:PRK03918   700 KEELEEREK 708
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1320-1998 7.12e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.84  E-value: 7.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1320 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE---ASNSEKIHLLQEALFASEQRLLAEREELV 1396
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmlEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1397 NENKAVTEKLTKATADAVL----AETAFTEKINELNLEKESVFSKSLQFEKHNEALlreKDELERKYSELLDEKKS-LEN 1471
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMhfrsLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDrIEQ 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1472 AFSDMKRE-QELDFSAKRLLVQENTtLKYSIEALEEELKKKN-LENQELIACRSDLSDLLKEAQDARRTLENELAAVSHA 1549
Cdd:pfam15921  272 LISEHEVEiTGLTEKASSARSQANS-IQSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1550 KQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKA-------------------RVLDKESFLLER 1610
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhlrRELDDRNMEVQR 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1611 MEL------QNNIGFLEKEVEEMREKNKEFLTEKELLVQ---EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1681
Cdd:pfam15921  431 LEAllkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1682 SLSVSKAELEDVHSCVSVMLDELQHKYevTEKEKMELVQ---ENESLHAEWKSLVIineEILKEKEKLSKEYYKLHEKVV 1758
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLK--NEGDHLRNVQtecEALKLQMAEKDKVI---EILRQQIENMTQLVGQHGRTA 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1759 ALLEQTDADFSCRLlvseGKHELLLEEMSNLA----LKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqe 1834
Cdd:pfam15921  586 GAMQVEKAQLEKEI----NDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1835 kietLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE-ELKK-----------EFEALKLAAAQKS 1902
Cdd:pfam15921  659 ----LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQtrntlksmegsDGHAMKVAMGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1903 Q------QLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLNNQL-------------LEMKKSlPSNTLRESTLKKE 1963
Cdd:pfam15921  735 QitakrgQIDALQSKIQFLEEAMTNANKE---KHFLKEEKNKLSQELstvateknkmageLEVLRS-QERRLKEKVANME 810

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2024460238 1964 IDEERASLQksISDTSALITQKDEELEKLRNEITV 1998
Cdd:pfam15921  811 VALDKASLQ--FAECQDIIQRQEQESVRLKLQHTL 843
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1740-2039 8.02e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 8.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1740 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQ 1819
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEEL---------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1820 TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAA 1899
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1900 QKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTS 1979
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1980 ALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSE 2039
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1621-2035 3.53e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 3.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1621 EKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM 1700
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1701 LDELQHKYEVTEkEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQtdadfscrllvsegkhe 1780
Cdd:PRK03918   268 IEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER----------------- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1781 llLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLaslensrqtnEKLQNELDMLK 1860
Cdd:PRK03918   330 --IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----------EKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1861 QNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEEN-----VKLAEELGRSRDEVtshQKLEEE 1935
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKEL---KEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1936 RSVLNNQLLEMKKSLpSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2015
Cdd:PRK03918   475 ERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          410       420
                   ....*....|....*....|
gi 2024460238 2016 LESDKLKLEEKVKNLEQKLK 2035
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELA 573
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 61-122 4.18e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 65.09  E-value: 4.18e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238   61 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRP 122
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2160-2176 7.75e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.75e-08
                           10
                   ....*....|....*..
gi 2024460238 2160 RPYCDTCEMFGHWTADC 2176
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2120-2137 5.65e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.65e-04
                           10
                   ....*....|....*...
gi 2024460238 2120 RLFCDICGCFDlHDTEDC 2137
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
ClyA_NheA-like cd22654
Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This ...
 727-1006 1.09e-03

Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This model contains Bacillus cereus tripartite non-hemolytic enterotoxin (Nhe) component A (NheA), a member of the cytolysin A (ClyA) family of alpha pore-forming toxins (alpha-PFTs). Non-hemolytic enterotoxin (Nhe), despite its name, is hemolytic and able to lyse erythrocytes from various mammalian organisms. It consists of three proteins, NheA, NheB and NheC, encoded by one operon containing three genes nheA, nheB and nheC, respectively. Separately, these three proteins show no toxicity; maximal activity is seen only when all three components are presented. The NheB and NheC components are able to bind to cell membranes while NheA is not; NheC primes the host cell for the formation of ion permeable NheB/C pores. Binding of NheA to NheB/NheC is thought to be the final stage of pore formation. Structure of NheA shows an elongated, almost entirely alpha-helical protein with an enlarged "head" domain compared with other cytolysins, displaying on its surface an enlarged beta-tongue which is of amphipathic rather than hydrophobic nature. It has been proposed that NheA could even form beta-barrel pores.


Pssm-ID: 439152 [Multi-domain]  Cd Length: 333  Bit Score: 43.41  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  727 SLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNletekvggsskvsnltkelqgkeqkllDLEKNLS 806
Cdd:cd22654     66 NFSQRFNNYYDKLYDLAGKINEDEQAKEDFLNGINKLQSQLQTIQN---------------------------SMEQTSS 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  807 AVNQVKDSLEKELQLLKEKFTSAVD--GAENAQRA-MQETINKLNQ--KEEQFALMSSELEQLKSNLTVMETKLKEREER 881
Cdd:cd22654    119 NLNRFKTLLDADSKNFSTDAKKAIDslSGSNGEIAqLRTQIKTINDeiQEELTKILNRPIEVGDGSINIGKQVFTITITT 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  882 EQQLTEAKVKLENDIAEIMKSSGDssaQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE--QSQQET 959
Cdd:cd22654    199 ATTKTVDVTSIGGLINGIGNASDD---EVKEAANKIQQKQKELVDLIKKLSDAEIQATQLTLVEDQVNGFTEliKRQIAT 275

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2024460238  960 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYE--KETSEMITKH 1006
Cdd:cd22654    276 LENLVEDWEMLNQNMNQLQTNVNSGKIDSKLLQKQLKqiKKISDELNKQ 324
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.13e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.13e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.26e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.26e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 217-282 2.62e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.52  E-value: 2.62e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238   217 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPRYGLFAPVHKVT 282
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 61-126 2.89e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 2.89e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238    61 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLRGIFTRPSKLS 126
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 670-1494 9.98e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.23  E-value: 9.98e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  670 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 730
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  731 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 799
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  800 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 879
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  880 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 953
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  954 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1026
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1027 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1090
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1091 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1154
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1155 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1234
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1235 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1314
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1315 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1388
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1389 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1465
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024460238 1466 KKSLENAFSDMKREQELDFSAKRLLVQEN 1494
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1320-2036 2.89e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 2.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1320 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1391
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1392 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1471
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1472 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1551
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1552 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKN 1631
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1632 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1711
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1712 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1774
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1775 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1820
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1821 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1900
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1901 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1980
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1981 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2036
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 406-1246 3.23e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 3.23e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  406 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE-RKRQISEDPENVATVSEK--SRIMELE 482
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEqQKQILRERLANLERQLEEleAQLEELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  483 RDLALRVKEVAELRGRLEsskhiddvdtslSLLQEISSLQEKMAAAGKEhQREMSSLKEKFESSEEALRKEIKTLSASNE 562
Cdd:TIGR02168  330 SKLDELAEELAELEEKLE------------ELKEELESLEAELEELEAE-LEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  563 RMGKENESLKTKLDHANKEnsdvielwKSKLESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSN 642
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDR--------RERLQQEIEELLKKLEEAELK------ELQAELEELEEELEELQEELERLEEA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  643 LKLKQEneksqhlkEIEALKAKLLEvTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQT 722
Cdd:TIGR02168  463 LEELRE--------ELEEAEQALDA-AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  723 K--------LIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSeqlQAAEKQIQNLETEKVGGSSKVSNLTKELQGK 794
Cdd:TIGR02168  534 GyeaaieaaLGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLD---SIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  795 EQKLLDLEKNLSAVNQVKDSLEKELQLLKEK------FT----------SAVDGAENAQRAMQETINKLNQKEEQFALMS 858
Cdd:TIGR02168  611 DPKLRKALSYLLGGVLVVDDLDNALELAKKLrpgyriVTldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  859 SELEQLKSNLTVMETKLkereereQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKA 938
Cdd:TIGR02168  691 EKIAELEKALAELRKEL-------EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  939 VQLQKNVEQTaqkaeqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsemitkhdadikgfKQNLL 1018
Cdd:TIGR02168  764 EELEERLEEA--------EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL---------------NEEAA 820

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1019 DAEEALKAAQKKNDELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLL 1094
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSedieSLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1095 SQHLEMESKILLVQQDREELWTKNEELNsENKKILKQKEA--AEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQ 1172
Cdd:TIGR02168  901 EELRELESKRSELRRELEELREKLAQLE-LRLEGLEVRIDnlQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238 1173 ENDALRSSESTLLQQLKELQANKDAVDvacqkhiKEREELEHYQKLLEEndrVIKDKDDVI-QRLQSSYDDLARN 1246
Cdd:TIGR02168  980 KIKELGPVNLAAIEEYEELKERYDFLT-------AQKEDLTEAKETLEE---AIEEIDREArERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 358-1049 5.78e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 5.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  358 LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHdrhvLEMEAKMDQLRAMVEAADREKVELLNQLEEEKR 437
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----SELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  438 KVEDLQFRVEEESITKGDLERKRQisEDPENVATVSEKsrIMELERDLALRVKEVAELRGRLESSKhiddvdtslSLLQE 517
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLD--ELAEELAELEEK--LEELKEELESLEAELEELEAELEELE---------SRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  518 ISSLQEKMAAAGKEHQREMSSLKEKFESseeaLRKEIKTLSASNERMGKENESLKTKLDHANKE----NSDVIELWKSKL 593
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIER----LEARLERLEDRRERLQQEIEELLKKLEEAELKelqaELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  594 ESAIASHQQAMEELKVSFNKGVGAQTA---EFAELKTQMEKVKLDYENEMSNLKLKQENEKSQH-LKEIEALKAKLLEVT 669
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAaerELAQLQARLDSLERLQENLEGFSEGVKALLKNQSgLSGILGVLSELISVD 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  670 EEKEQTLEnlkAKLESVEDQHLVEMEDTLNKLQEA--EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQK 747
Cdd:TIGR02168  533 EGYEAAIE---AALGGRLQAVVVENLNAAKKAIAFlkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  748 ANSEGKLEIQKLSEQL-------QAAEKQIQNLETEK---------------VGGSSKVSNLT----KELQGKEQKLLDL 801
Cdd:TIGR02168  610 FDPKLRKALSYLLGGVlvvddldNALELAKKLRPGYRivtldgdlvrpggviTGGSAKTNSSIlerrREIEELEEKIEEL 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  802 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREER 881
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  882 EQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLK 961
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ-IE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  962 THQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEketsemitKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEEL 1041
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERA--------SLEEALALLRSELEELSEELRELESKRSELRRELEEL 920


                   ....*...
gi 2024460238 1042 KKQAEQAK 1049
Cdd:TIGR02168  921 REKLAQLE 928
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 873-1750 9.85e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 9.85e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  873 TKLKER-EEREQQLTEAKVKLE--NDIAEIMKSSGDS-SAQLMKMNDELRLKErQLEQIQLELTKAneKAVQLQKNVEQT 948
Cdd:TIGR02168  168 SKYKERrKETERKLERTRENLDrlEDILNELERQLKSlERQAEKAERYKELKA-ELRELELALLVL--RLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  949 AQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSE------MITKHDADIKGFKQNLLDAEE 1022
Cdd:TIGR02168  245 QEELKEAEEE-LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrleqQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1023 ALKAAQKKNDELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1098
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKeeleSLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1099 EMESKILLVQQDREELWTKNEELNsenkkilkqKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALR 1178
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELL---------KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1179 SSESTLLQQLKELQANKDAVDVACQKHIKERE---ELEHYQKLLEENDRVIKDKDDVIQR--------LQSSYDDLA-RN 1246
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEgvkALLKNQSGLSGILGVLSELISVDEGyeaaieaaLGGRLQAVVvEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1247 QRELLQEVSILTAERDS-------AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQA 1319
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELGrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1320 LKLRKdEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREasNSEKIHLLQEALFASEQRLLAEREELvnen 1399
Cdd:TIGR02168  635 LELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEE--LEEKIEELEEKIAELEKALAELRKEL---- 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1400 kavtEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE 1479
Cdd:TIGR02168  708 ----EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1480 QEldfsakrllvqentTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNT 1559
Cdd:TIGR02168  784 IE--------------ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1560 CSSDIEILNRERTELQDKCQKLTGEVENMKEnltvekkarvlDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKE 1639
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLN-----------ERASLEEALALLRSELEELSEELRELESKRSELRRELE 918

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1640 LLVQEKEKSETKLEEvikekmilyketeqLASKIEQLKSDFTSLsvskaeledvhscVSVMLDELQHKYEVTEKEKMELV 1719
Cdd:TIGR02168  919 ELREKLAQLELRLEG--------------LEVRIDNLQERLSEE-------------YSLTLEEAEALENKIEDDEEEAR 971

                          890       900       910
                   ....*....|....*....|....*....|.
gi 2024460238 1720 QENESLHAEWKSLVIINEEILKEKEKLSKEY 1750
Cdd:TIGR02168  972 RRLKRLENKIKELGPVNLAAIEEYEELKERY 1002
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 916-1810 1.38e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 90.13  E-value: 1.38e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  916 ELRLKERQLEQIQLELTKANEKAVQLQKNVEqtaqKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKY 995
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRRERE----KAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEEL 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  996 EKETSEmitkhdadikgfkqnlldAEEALKAAQKKNDELETQAEELKKQAE-QAKSLSSVLASARKEIELMSDKMRDLIS 1074
Cdd:TIGR02169  254 EKLTEE------------------ISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1075 EKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1154
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1155 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQ 1234
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE---WKLEQLAADLSKYEQELY 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1235 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSRE-ELCVSLANT 1313
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1314 ANENQA--------LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASE 1385
Cdd:TIGR02169  553 VVEDDAvakeaielLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAA 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1386 QRLLAERE------ELVNENKAVTEKLTKATADAVLAeTAFTEKINELNLEKESVfskslqfEKHNEALLREKDELERKY 1459
Cdd:TIGR02169  633 RRLMGKYRmvtlegELFEKSGAMTGGSRAPRGGILFS-RSEPAELQRLRERLEGL-------KRELSSLQSELRRIENRL 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1460 SELLDEKKSLENAFSDMKREQELdfsakrlLVQENTTLKYSIEALEEELKKKNlenQELIACRSDLSDLLKEAQDARRTL 1539
Cdd:TIGR02169  705 DELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1540 ENELAAVSHAKQVLSSSFntcssdIEILNRERTELQDKCQKLTGEVENmkenLTVEKKARVLDKEsfllermelqnnigF 1619
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSR------IPEIQAELSKLEEEVSRIEARLRE----IEQKLNRLTLEKE--------------Y 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1620 LEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSV 1699
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1700 MLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEIL------KEKEKLSKEYYKLhEKVVALLEQTDADFSCRLL 1773
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELsledvqAELQRVEEEIRAL-EPVNMLAIQEYEEVLKRLD 989

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 2024460238 1774 VSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEA 1810
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEA 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1033-1887 2.67e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.67e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1033 ELETQAEELKKQAEQA---KSLSSVLASARKEIELMS-----DKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKI 1104
Cdd:TIGR02168  197 ELERQLKSLERQAEKAeryKELKAELRELELALLVLRleelrEELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1105 LLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQestekvalisekskLLSEIETAQADLLKITQENDALRSSESTL 1184
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLAN--------------LERQLEELEAQLEELESKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1185 LQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLaRNQRELLQevsiltaerdsa 1264
Cdd:TIGR02168  343 EEKLEELKEELES----------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL-ELQIASLN------------ 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1265 qekdldlksthialkNEIDCLLQTNRSLQSEKEMLLKSREELcvslantanENQALKLRKDEMQTELETEREKLEKMTKD 1344
Cdd:TIGR02168  400 ---------------NEIERLEARLERLEDRRERLQQEIEEL---------LKKLEEAELKELQAELEELEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1345 NMDLKASLSSLSNFLEEMKSSREASNSEKIHLlqEALFASEQRLLAEREELVNENKAVT-EKLTKATADAVLAETAFTEk 1423
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQL--QARLDSLERLQENLEGFSEGVKALLkNQSGLSGILGVLSELISVD- 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1424 iNELNLEKESVFSKSLQfekhneALLREKDELERKYSELLDEKKSLENAFS--DMKREQELDFSAKRLLVQENTTLKYSI 1501
Cdd:TIGR02168  533 -EGYEAAIEAALGGRLQ------AVVVENLNAAKKAIAFLKQNELGRVTFLplDSIKGTEIQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1502 EALEEELKKKNLENQELIACRsdLSDLLKEAQDARRTLENELAAVSHAKQVLSSSF-------NTCSSD------IEILN 1568
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVL--VVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGvitggsaKTNSSIlerrreIEELE 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1569 RERTELQDKCQKLTGEVENMKENLT-VEKKARVLDKESFLLERM--ELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEK 1645
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEeLEEELEQLRKELEELSRQisALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1646 EKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESL 1725
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1726 HAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvSEGKHELLLEEMSNLALKLREIErlqaqtfm 1805
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS--------LEEALALLRSELEELSEELRELE-------- 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1806 qkfeadKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQT-NEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKV 1884
Cdd:TIGR02168  908 ------SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981


                   ...
gi 2024460238 1885 EEL 1887
Cdd:TIGR02168  982 KEL 984
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 816-1666 1.34e-16

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 86.56  E-value: 1.34e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  816 EKELQLLKEKFTSAVDGAENAQRAMQETINKLN-QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEN 894
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKlKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  895 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQD 972
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  973 QLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLS 1052
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1053 SVLASARKEIELMSDKMRDLISEKETLaQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1132
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1133 EAAEAKSRQESTEKvaliSEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREEL 1212
Cdd:pfam02463  488 LLLSRQKLEERSQK----ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1213 EHYQKLLEENDR-------VIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCL 1285
Cdd:pfam02463  564 QKLVRALTELPLgarklrlLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1286 LQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSS 1365
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1366 REASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHN 1445
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1446 EALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQ-ELIACRSD 1524
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLkEEELEEQK 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1525 LSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARVLDKE 1604
Cdd:pfam02463  884 LKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238 1605 SFLLERMELQNNigfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKET 1666
Cdd:pfam02463  964 RLLLAKEELGKV---NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1032-1676 1.63e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.63e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1032 DELETQAEELKKQAEQA---KSLSSVLAsaRKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQ 1108
Cdd:COG1196    196 GELERQLEPLERQAEKAeryRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1109 QDREELwtkNEELNsenkkilkqkeaaeaksrqestekvALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1188
Cdd:COG1196    274 LELEEL---ELELE-------------------------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1189 KELQankdavdvacQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKD 1268
Cdd:COG1196    326 AELE----------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1269 LDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDL 1348
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1349 KASLSSLSNFLEEMKSSREASNSEkihLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELN 1428
Cdd:COG1196    476 EAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1429 LEKESVFSKSLQFEKHNEA--LLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEE 1506
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1507 ELKKKnlenqeliacrsdlsdLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVE 1586
Cdd:COG1196    633 EAALR----------------RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1587 NMKENLTVEKKARVLDKEsfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEkmiLYKET 1666
Cdd:COG1196    697 EALLAEEEEERELAEAEE----ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE---LEREL 769

                          650
                   ....*....|
gi 2024460238 1667 EQLASKIEQL 1676
Cdd:COG1196    770 ERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 416-1266 1.93e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 86.28  E-value: 1.93e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  416 AMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAEL 495
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  496 RGRLES-SKHIDDVDtslsllQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTK 574
Cdd:TIGR02169  243 ERQLASlEEELEKLT------EEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  575 LDHANKENSDVIELwKSKLESAIASHQQAMEELKVSfnkgVGAQTAEFAELKTQMEKVK-----LDYENEMSNLKLKQEN 649
Cdd:TIGR02169  317 LEDAEERLAKLEAE-IDKLLAEIEELEREIEEERKR----RDKLTEEYAELKEELEDLRaeleeVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  650 EKSQHLK----EIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlvemedtlNKLQEaeikvkELDVLQAKCNEQTKLI 725
Cdd:TIGR02169  392 EKLEKLKreinELKRELDRLQEELQRLSEELADLNAAIAGIEAKI--------NELEE------EKEDKALEIKKQEWKL 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  726 GSLTQQIRASEEKLLDLAALQKANSEgklEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQG-----------K 794
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEK---ELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlgsvG 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  795 EQKLLDLE----KNLSAVNQVKDSLEKE-LQLLKEKftsavdgaeNAQRAMQETINKLNQKEEQ-----------FALMS 858
Cdd:TIGR02169  535 ERYATAIEvaagNRLNNVVVEDDAVAKEaIELLKRR---------KAGRATFLPLNKMRDERRDlsilsedgvigFAVDL 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  859 SELEQLKSNLTVM---ETKLKEREE--REQQLTEAKVKLENDIAE--------IMKSSGDSS------AQLMKMNDELRL 919
Cdd:TIGR02169  606 VEFDPKYEPAFKYvfgDTLVVEDIEaaRRLMGKYRMVTLEGELFEksgamtggSRAPRGGILfsrsepAELQRLRERLEG 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  920 KERQLEQIQLELTKAnekavqlqknveqtaqkaeqsqqetlkthQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEt 999
Cdd:TIGR02169  686 LKRELSSLQSELRRI-----------------------------ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL- 735

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1000 SEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAE--QAKSLSSVLASARKEIELMSDKMRDLISEKE 1077
Cdd:TIGR02169  736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSKLEEEVSRIEARLR 815

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1078 TLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLL 1157
Cdd:TIGR02169  816 EIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELE 895

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1158 SEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRV---IKDKDDVIQ 1234
Cdd:TIGR02169  896 AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVeeeIRALEPVNM 975

                          890       900       910
                   ....*....|....*....|....*....|..
gi 2024460238 1235 RLQSSYDDLARNQRELLQEVSILTAERDSAQE 1266
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 695-1344 4.75e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.99  E-value: 4.75e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  695 EDTLNKLQEAEikvKELDVLQAKCNEQTKLIGSLTQQIRA--------SEEKLLDLAALqkansegKLEIQKLSEQLQAA 766
Cdd:COG1196    175 EEAERKLEATE---ENLERLEDILGELERQLEPLERQAEKaeryrelkEELKELEAELL-------LLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  767 EKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 846
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  847 LNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 926
Cdd:COG1196    325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  927 IQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDmKKQMETSQNQYKDLQAKYEKETSEMITKH 1006
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL-EEEEEALLELLAELLEEAALLEAALAELL 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1007 DADIKgfkqnlLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARK---------EIELMSDKMRDLISEKE 1077
Cdd:COG1196    484 EELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveaayeaalEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1078 TLAQERNTLKLEKE-----------------SLLSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEAAEAKSR 1140
Cdd:COG1196    558 VAAAAIEYLKAAKAgratflpldkiraraalAAALARGAIGAAVDLVASDLREA----DARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1141 QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLE 1220
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1221 ENDRviKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKsthiALKNEIdcllqtnRSLQSEKEML- 1299
Cdd:COG1196    714 EERL--EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE----ELEREL-------ERLEREIEALg 780

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1300 ---LKSREELcvslantanenQALKLRKDEMQTE---LETEREKLEKMTKD 1344
Cdd:COG1196    781 pvnLLAIEEY-----------EELEERYDFLSEQredLEEARETLEEAIEE 820
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 354-1020 5.64e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 5.64e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  354 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDrhvlEMEAKMDQLRAMVEAADREKVELLNQLE 433
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSKVA 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  434 EEKRKVEDLQFRVEEESITKGDLERKRQI-SEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLEsskhiDDVDTSL 512
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE-----RLEEALE 464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  513 SLLQEISSLQEKMAAAGKEHQREMSSLK--EKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKensdvielWK 590
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEG--------YE 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  591 SKLESAIASHQQAME-------ELKVSFNKGVGAQTAEFAELKTqmekVKLDYENEMSNLKLKQENEKSQHLKEIEALKA 663
Cdd:TIGR02168  537 AAIEAALGGRLQAVVvenlnaaKKAIAFLKQNELGRVTFLPLDS----IKGTEIQGNDREILKNIEGFLGVAKDLVKFDP 612

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  664 KL----------LEVTEEKEQTLENLKAKLES----VEDQHLV----------------------EMEDTLNKLQEAEIK 707
Cdd:TIGR02168  613 KLrkalsyllggVLVVDDLDNALELAKKLRPGyrivTLDGDLVrpggvitggsaktnssilerrrEIEELEEKIEELEEK 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  708 VKELDV-LQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSN 786
Cdd:TIGR02168  693 IAELEKaLAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  787 LTKELQGKEQKLLDLEK-------NLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSS 859
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAqieqlkeELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  860 ELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAV 939
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  940 QLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDL---------QAKYEKETSEMITKHDADI 1010
Cdd:TIGR02168  933 GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaieEYEELKERYDFLTAQKEDL 1012

                          730
                   ....*....|
gi 2024460238 1011 KGFKQNLLDA 1020
Cdd:TIGR02168 1013 TEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1003-1896 5.71e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.73  E-value: 5.71e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1003 ITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAkslssvlasarkeielmsDKMRDLISEKEtlaqe 1082
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA------------------ERYQALLKEKR----- 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1083 rntlKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEkskllsEIET 1162
Cdd:TIGR02169  222 ----EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE------EQLR 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1163 AQADLLKITQENDALRSSESTLLQQLKELQAnkdavdvacqKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD 1242
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEE----------RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1243 LARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKL 1322
Cdd:TIGR02169  362 LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1323 RKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMkssreasnSEKIHLLQEALFASEQRLLAEREElVNENKAV 1402
Cdd:TIGR02169  442 EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV--------EKELSKLQRELAEAEAQARASEER-VRGGRAV 512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1403 TE--------------KLTKATADAVLA-ETAFTEKINELNLEKESVFSKSLQFEKHNEA-----LLREKDELERKYSEL 1462
Cdd:TIGR02169  513 EEvlkasiqgvhgtvaQLGSVGERYATAiEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAgratfLPLNKMRDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1463 LDEKKSLENAFSDMKREQEldFSAKRLLVQENTTLKYSIEAleeelKKKNLENQELIACRSDL----------SDLLKEA 1532
Cdd:TIGR02169  593 LSEDGVIGFAVDLVEFDPK--YEPAFKYVFGDTLVVEDIEA-----ARRLMGKYRMVTLEGELfeksgamtggSRAPRGG 665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1533 QDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTvekkaRVLDKESFLLERME 1612
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE-----QLEQEEEKLKERLE 740

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1613 -LQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVikEKMILYKETEQLASKIEQLKSDFTSLSVSKAELE 1691
Cdd:TIGR02169  741 eLEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVSRIEARLREIE 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1692 dvhscvsVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALleqtdadfscr 1771
Cdd:TIGR02169  819 -------QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL----------- 880

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1772 llvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIH------QEKIETLASLENS 1845
Cdd:TIGR02169  881 ----ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEdpkgedEEIPEEELSLEDV 956

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1846 RQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKL 1896
Cdd:TIGR02169  957 QAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1194 9.68e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 9.68e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  530 KEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwKSKLESAIASHQQAMEELKV 609
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRERLANLER 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  610 SFNKG------VGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKsqhlKEIEALKAKLLEVTEEKEQTLENLKAKL 683
Cdd:TIGR02168  317 QLEELeaqleeLESKLDELAEELAELEEKLEELKEELESLEAELEELE----AELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  684 ESVEDQ--HLVEMEDTLNKLQ---EAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQK 758
Cdd:TIGR02168  393 LQIASLnnEIERLEARLERLEdrrERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  759 LSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKElqllkEKFTSAVDGA----- 833
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-----EGYEAAIEAAlggrl 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  834 -----ENAQRAMQeTINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQ----LTEAKVKLENDIAE------ 898
Cdd:TIGR02168  548 qavvvENLNAAKK-AIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGvakdLVKFDPKLRKALSYllggvl 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  899 IMKSSGDSSAQLMKMNDELRL---------------------------KERQLEQIQLELTKANEKAVQLQKNVEQTAQK 951
Cdd:TIGR02168  627 VVDDLDNALELAKKLRPGYRIvtldgdlvrpggvitggsaktnssileRRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  952 AEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmITKHDADIKGFKQNLLDAEEALKAAQKKN 1031
Cdd:TIGR02168  707 LEELEEE-LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-LTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1032 DELETQAEELKkqaEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1111
Cdd:TIGR02168  785 EELEAQIEQLK---EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1112 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1191
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941


                   ...
gi 2024460238 1192 QAN 1194
Cdd:TIGR02168  942 QER 944
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 346-1093 1.97e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.73  E-value: 1.97e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  346 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQeLALVRDghdrhVLEMEAKMDQLRAMVEA----- 420
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ-LRVKEK-----IGELEAEIASLERSIAEkerel 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  421 --ADREKVELLNQLEEEKRKVEDLQFRVEEESItkgdleRKRQISEDPENVATVSEK--SRIMELERDLALRVKEVAELR 496
Cdd:TIGR02169  318 edAEERLAKLEAEIDKLLAEIEELEREIEEERK------RRDKLTEEYAELKEELEDlrAELEEVDKEFAETRDELKDYR 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  497 GRLESSKH-IDDVDTSLSLLQEissLQEKMAAAGKEHQREMSSLKEK---FESSEEALRKEIK-------TLSASNERMG 565
Cdd:TIGR02169  392 EKLEKLKReINELKRELDRLQE---ELQRLSEELADLNAAIAGIEAKineLEEEKEDKALEIKkqewkleQLAADLSKYE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  566 KENESLKTKLDHANKENSDVielwKSKLESAIASHQQ---------AMEELKVSFNKGVGAQTAEFAELKTQMEK-VKLD 635
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKL----QRELAEAEAQARAseervrggrAVEEVLKASIQGVHGTVAQLGSVGERYATaIEVA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  636 YENEMSNLKLKQEN---EKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQ--HLVEMEDtlnKLQEAEIKVKE 710
Cdd:TIGR02169  545 AGNRLNNVVVEDDAvakEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFavDLVEFDP---KYEPAFKYVFG 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  711 LDVLQAKCNEQTKLIGSLTQQIRASE--EK-------LLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 781
Cdd:TIGR02169  622 DTLVVEDIEAARRLMGKYRMVTLEGElfEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  782 SKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSEL 861
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL 781

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  862 EQLKSnltvmetklKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRL--KERQLEQIQLELTKANEKAV 939
Cdd:TIGR02169  782 NDLEA---------RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYleKEIQELQEQRIDLKEQIKSI 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  940 Q-----LQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETsemitKHDADIKGFK 1014
Cdd:TIGR02169  853 EkeienLNGKKEELEEELEELEAA-LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR-----KRLSELKAKL 926

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1015 QNLLDAEEALKAAQKKNDE-------LETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLK 1087
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEipeeelsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*.
gi 2024460238 1088 LEKESL 1093
Cdd:TIGR02169 1007 ERIEEY 1012
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 601-1446 2.18e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  601 QQAMEELKVsfnkgVGAQTAEF----AELKTQMEKVKLDYENEMSNLKL---KQENEKSQHLKEIEALKAKLLEVT---E 670
Cdd:TIGR02169  173 EKALEELEE-----VEENIERLdliiDEKRQQLERLRREREKAERYQALlkeKREYEGYELLKEKEALERQKEAIErqlA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  671 EKEQTLENLKAKLESVEDQhLVEMEDTLNKLqEAEIKVK---ELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQK 747
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKR-LEEIEQLLEEL-NKKIKDLgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  748 ansEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKft 827
Cdd:TIGR02169  326 ---KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE-- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  828 savdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSS 907
Cdd:TIGR02169  401 ------------INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  908 AQLMKMNDELRLKERQLEQIQLELTKAnekavQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ-- 985
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRELAEA-----EAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIev 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  986 ---------------------NQYKDLQA---------KYEKETSEMITKHDADIKGFKQNLLDAE-------------- 1021
Cdd:TIGR02169  544 aagnrlnnvvveddavakeaiELLKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDpkyepafkyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1022 ---EALKAAQKKNDE--LETQAEELKKQ-------AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLE 1089
Cdd:TIGR02169  624 lvvEDIEAARRLMGKyrMVTLEGELFEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1090 KESLLSQHLEMESKILLVQQDREELwtkNEELNSENKKIlkqkEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLK 1169
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQL---EQEEEKLKERL----EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1170 ITQENDALRSSESTllQQLKELQANKDAVDvacqkhikereelehyqklleendrvikdkdDVIQRLQSSYDDLARNQRE 1249
Cdd:TIGR02169  777 LEEALNDLEARLSH--SRIPEIQAELSKLE-------------------------------EEVSRIEARLREIEQKLNR 823

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1250 LLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQT 1329
Cdd:TIGR02169  824 LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1330 ELETEREKLEKMTKDNMDLKASLSSLSNFLEEM-KSSREASNSEKIHLLQEALFASEQRLLAEREEL--VNeNKAVTE-K 1405
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELKAKLEALEEELSEIeDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepVN-MLAIQEyE 982

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 2024460238 1406 LTKATAD------AVLAE--TAFTEKINELNLEKESVFSKSlqFEKHNE 1446
Cdd:TIGR02169  983 EVLKRLDelkekrAKLEEerKAILERIEEYEKKKREVFMEA--FEAINE 1029
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 692-1590 3.83e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.57  E-value: 3.83e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  692 VEMEDTLNKLQEAEIKVKELDVLQAKCNEQTkligsltQQIRASEEKLLDLAALQKanSEGKLEIQKLSEQLQAAEKQIQ 771
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQL-------ERLRREREKAERYQALLK--EKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  772 NLETEkvggsskVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQllkekftsavDGAENAQRAMQETINKLnqke 851
Cdd:TIGR02169  241 AIERQ-------LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK----------DLGEEEQLRVKEKIGEL---- 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  852 eqfalmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmndelrlkERQLEQIQLEL 931
Cdd:TIGR02169  300 ------EAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL---------------------EREIEEERKRR 352

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  932 TKANEKAVQLQKNVEQTAQKAEQsQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmITKHDADIK 1011
Cdd:TIGR02169  353 DKLTEEYAELKEELEDLRAELEE-VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEE-LADLNAAIA 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1012 GFKQNLLDAEEalkaaqkkndELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKE 1091
Cdd:TIGR02169  431 GIEAKINELEE----------EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1092 SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQE---STEKVAliSEKSKLLSEIETAQADLL 1168
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNvvvEDDAVA--KEAIELLKRRKAGRATFL 578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1169 KITQENDALRssestLLQQLKELQANKDAVD-VACQKHIKER-----------EELEHYQKLLEENDRV-----IKDKDD 1231
Cdd:TIGR02169  579 PLNKMRDERR-----DLSILSEDGVIGFAVDlVEFDPKYEPAfkyvfgdtlvvEDIEAARRLMGKYRMVtlegeLFEKSG 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1232 VIQRLQSSYDDLARNQRELLQEVSILTAERDSaqekdldlksthiaLKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLA 1311
Cdd:TIGR02169  654 AMTGGSRAPRGGILFSRSEPAELQRLRERLEG--------------LKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1312 NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKssreasnsEKIHLLQEALFASEQRLLAE 1391
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELE--------EDLHKLEEALNDLEARLSHS 791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1392 R-----------EELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYS 1460
Cdd:TIGR02169  792 RipeiqaelsklEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1461 ELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQD------ 1534
Cdd:TIGR02169  872 ELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeel 951

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238 1535 ARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKE 1590
Cdd:TIGR02169  952 SLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
PTZ00121 PTZ00121
MAEBL; Provisional
 530-1330 7.02e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.87  E-value: 7.02e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  530 KEHQREMSSLKEKFESSEEALRKEiktlsasnerMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKV 609
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTE----------TGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKR 1153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  610 SFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKakllevTEEKEQTLENLKAKLESVEDQ 689
Cdd:PTZ00121  1154 VEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAAR------KAEEERKAEEARKAEDAKKAE 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  690 HLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQ 769
Cdd:PTZ00121  1228 AVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  770 IQNLETEKvggssKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLN- 848
Cdd:PTZ00121  1308 KKKAEEAK-----KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADa 1382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  849 -QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndiaEIMKS-SGDSSAQLMKMNDELRLKERQLEQ 926
Cdd:PTZ00121  1383 aKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE----EKKKAdEAKKKAEEAKKADEAKKKAEEAKK 1458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  927 IQLELTKANEKavqlqKNVEQTAQKAEQSQQ-ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK 1005
Cdd:PTZ00121  1459 AEEAKKKAEEA-----KKADEAKKKAEEAKKaDEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1006 HDADIKGFKQNLLDAEEALKAAQKKNDELETQAEElKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNT 1085
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA 1612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1086 LKLEKESLLSQHL----EMESKILLVQQDREELWTKNEELN--SENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSE 1159
Cdd:PTZ00121  1613 KKAEEAKIKAEELkkaeEEKKKVEQLKKKEAEEKKKAEELKkaEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1160 IETAQADLLKITQENDALRSSESTLLQQL-KELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQS 1238
Cdd:PTZ00121  1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELkKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEE 1772

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1239 syddlARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQ 1318
Cdd:PTZ00121  1773 -----IRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEAD 1847

                          810
                   ....*....|..
gi 2024460238 1319 ALKLRKDEMQTE 1330
Cdd:PTZ00121  1848 AFEKHKFNKNNE 1859
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 357-1141 7.86e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.80  E-value: 7.86e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  357 ALKEKQQHIEQ--LLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlEMEAKMDQLRAMVEAAdrekVELLNQLEE 434
Cdd:TIGR02169  215 ALLKEKREYEGyeLLKEKEALERQKEAIERQLASLEEELE-----------KLTEEISELEKRLEEI----EQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  435 E-KRKVEDLQFRVEEE-SITKGDLER-KRQISEDPENVATVSEKSRIMELERDLALRvkEVAELRGRLESSKHIDDvdts 511
Cdd:TIGR02169  280 KiKDLGEEEQLRVKEKiGELEAEIASlERSIAEKERELEDAEERLAKLEAEIDKLLA--EIEELEREIEEERKRRD---- 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  512 lSLLQEISSLQEKMAAAgkehQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwKS 591
Cdd:TIGR02169  354 -KLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL-NA 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  592 KLESAIASHQQAMEELKVSFNKgVGAQTAEFAELKTQMEKVKLDYENEMSNLKlKQENEKSQHLKEIEALKAKL------ 665
Cdd:TIGR02169  428 AIAGIEAKINELEEEKEDKALE-IKKQEWKLEQLAADLSKYEQELYDLKEEYD-RVEKELSKLQRELAEAEAQAraseer 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  666 -------LEVTEEKEQTLENLKAKLESVEDQHLVEMEDTL-NKLQEAeikVKELDVLQAKCNEQTKL--IGSLT-QQIRA 734
Cdd:TIGR02169  506 vrggravEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAgNRLNNV---VVEDDAVAKEAIELLKRrkAGRATfLPLNK 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  735 SEEKLLDLAALQKANSEG-KLEIQKLSEQLQAAEKQI-------QNLETEK-VGGSSKVSNLTKEL-------------- 791
Cdd:TIGR02169  583 MRDERRDLSILSEDGVIGfAVDLVEFDPKYEPAFKYVfgdtlvvEDIEAARrLMGKYRMVTLEGELfeksgamtggsrap 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  792 QGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVM 871
Cdd:TIGR02169  663 RGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEL 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  872 ETKLKereEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND-ELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ 950
Cdd:TIGR02169  743 EEDLS---SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQ 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  951 K------AEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyEKETSEMITKHDADIKGFKQNLLDAEEAL 1024
Cdd:TIGR02169  820 KlnrltlEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE-LEELEAALRDLESRLGDLKKERDELEAQL 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1025 KAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEK---ETLAQERNTLKLEKESLLSQHLEME 1101
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAI 978

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 2024460238 1102 SKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQ 1141
Cdd:TIGR02169  979 QEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 755-1361 1.47e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 76.21  E-value: 1.47e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  755 EIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAE 834
Cdd:TIGR04523   41 KLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  835 NAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN 914
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  915 DEL---RLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKdl 991
Cdd:TIGR04523  201 LLLsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTE-ISNTQTQLNQLKDEQNKIKKQLSEKQKELE-- 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  992 qakyekETSEMITKHDADIKGFKQNLLDAEEalkaaQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRD 1071
Cdd:TIGR04523  278 ------QNNKKIKELEKQLNQLKSEISDLNN-----QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1072 LISEKETLAQERNTLKLEKEsllsqhlEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALIS 1151
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELE-------EKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1152 EKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDA----VDVACQKHIKEREELEHYQKLLEENDRVIK 1227
Cdd:TIGR04523  420 EKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESletqLKVLSRSINKIKQNLEQKQKELKSKEKELK 499

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1228 DKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKS---------THIALKNEIDCLLQTNRSLQSEKEM 1298
Cdd:TIGR04523  500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDelnkddfelKKENLEKEIDEKNKEIEELKQTQKS 579

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238 1299 LLKSREELCVSLANTANENQALK---LRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEE 1361
Cdd:TIGR04523  580 LKKKQEEKQELIDQKEKEKKDLIkeiEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 408-1211 2.46e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.93  E-value: 2.46e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  408 EAKMDQLRAMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESitkgDLERKRQISEDpENVATVSEKSRIMELERDlal 487
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN----ELHEKQKFYLR-QSVIDLQTKLQEMQMERD--- 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  488 rvkEVAELRGRLESSKH--IDDVDTSLSLLQEISSLQEKMAaagKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMG 565
Cdd:pfam15921  128 ---AMADIRRRESQSQEdlRNQLQNTVHELEAAKCLKEDML---EDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  566 K---ENESLKTkldhankensdvieLWKSKLESAIASHQQAMEElKVSFNKGvgaqtaEFAELKTQMEKVKLDYENEMSN 642
Cdd:pfam15921  202 KkiyEHDSMST--------------MHFRSLGSAISKILRELDT-EISYLKG------RIFPVEDQLEALKSESQNKIEL 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  643 LKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQ----------HLVEMEDTLNKLQEA-------- 704
Cdd:pfam15921  261 LLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQarnqnsmymrQLSDLESTVSQLRSElreakrmy 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  705 EIKVKELDVLQAKCNeqTKLIGSLTQQIRASEEKLLDLAALQKANSEgkleIQKLSEQLQAAEKQIQNLETEKVGGSSKV 784
Cdd:pfam15921  341 EDKIEELEKQLVLAN--SELTEARTERDQFSQESGNLDDQLQKLLAD----LHKREKELSLEKEQNKRLWDRDTGNSITI 414

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  785 SNLTKELQGKEQKLLDLEKNLSAvnqvkdsLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEqfaLMSSELEQL 864
Cdd:pfam15921  415 DHLRRELDDRNMEVQRLEALLKA-------MKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKE---MLRKVVEEL 484

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  865 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN------DELRLKERQLEQIQLELTKANEKA 938
Cdd:pfam15921  485 TAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQhlknegDHLRNVQTECEALKLQMAEKDKVI 564

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  939 VQLQKNVEQTAQKAEQsQQETLKTHQEELKKMQDQLTDMKKQMEtsqnQYKDLQAKYEKETSEMITKHdADIKGFKQNLL 1018
Cdd:pfam15921  565 EILRQQIENMTQLVGQ-HGRTAGAMQVEKAQLEKEINDRRLELQ----EFKILKDKKDAKIRELEARV-SDLELEKVKLV 638

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1019 DA-EEALKAA----QKKN---DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMR-DLISEKETLAQERNTLKle 1089
Cdd:pfam15921  639 NAgSERLRAVkdikQERDqllNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmQLKSAQSELEQTRNTLK-- 716

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1090 kesllSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRqestEKVALISEKSKLLSEIETAQADLLK 1169
Cdd:pfam15921  717 -----SMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANK----EKHFLKEEKNKLSQELSTVATEKNK 787

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 2024460238 1170 ITQENDALRSSESTLLQQLKELQANKDAVDVA---CQKHIKEREE 1211
Cdd:pfam15921  788 MAGELEVLRSQERRLKEKVANMEVALDKASLQfaeCQDIIQRQEQ 832
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 353-983 3.91e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 3.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  353 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlemeakmdQLRAMVEAADREKVELLNQL 432
Cdd:COG1196    217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELE------------------ELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  433 EEEKRKVEDLQFRVEEESITKGDLERKRQisedpenvatvSEKSRIMELERDLALRVKEVAELRGRLEsskhiddvdtsl 512
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIA-----------RLEERRRELEERLEELEEELAELEEELE------------ 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  513 SLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSK 592
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE--EA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  593 LESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEK 672
Cdd:COG1196    412 LLERLERLEEELEELEEA------LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  673 EQTLENLKAKLESVEDQHLVEMEDTLNKLQEA-------EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAL 745
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglagAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  746 QKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS----LEKELQL 821
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAalrrAVTLAGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  822 LKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 901
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  902 SSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK----------AEQSQQETlkthQEELKKMQ 971
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgpvnllAIEEYEEL----EERYDFLS 801

                          650
                   ....*....|..
gi 2024460238  972 DQLTDMKKQMET 983
Cdd:COG1196    802 EQREDLEEARET 813
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1325-2092 6.83e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.72  E-value: 6.83e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1325 DEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREasNSEKIHLLQEALFASEQRLLA-EREELVNENKAVT 1403
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--KAERYQALLKEKREYEGYELLkEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1404 EKLtkATADAVLAEtaFTEKINELNLEKESVFSKSLQFEKHNEALLR-EKDELERKYSELLDEKKSLENAFSDMKREQEL 1482
Cdd:TIGR02169  244 RQL--ASLEEELEK--LTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1483 DFSAKRLLVQENTTLKYSIEALEEELKKKNLEnqeliacRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSS 1562
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELEREIEEERKR-------RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1563 DIEILNRERTE-------LQDKCQKLTGEVENMKENLTVeKKARVLDKESfllERMELQNNIGFLEKEVEEMREKNKEFL 1635
Cdd:TIGR02169  393 KLEKLKREINElkreldrLQEELQRLSEELADLNAAIAG-IEAKINELEE---EKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1636 TEKELLVQEKEKSETKLEEVIKEkmILYKETEQLASKIEQLKSDFTSLsVSKAELEDVHSCVSvMLDELQHKY------- 1708
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRE--LAEAEAQARASEERVRGGRAVEE-VLKASIQGVHGTVA-QLGSVGERYataieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1709 ------------EVTEKEKMELVQENESLHAEWKSLVIINEEiLKEKEKLSK-----------EYYKLHEKVVA------ 1759
Cdd:TIGR02169  545 agnrlnnvvvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEdgvigfavdlvEFDPKYEPAFKyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1760 -LLEQTDAD----FSCRLLVSEGKhelLLEE---MSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAI 1831
Cdd:TIGR02169  624 lVVEDIEAArrlmGKYRMVTLEGE---LFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1832 HQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEE 1911
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1912 NVKLAEELGRSR-DEVTSH-QKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEI----------DEERASLQKSISDTS 1979
Cdd:TIGR02169  781 LNDLEARLSHSRiPEIQAElSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIqelqeqridlKEQIKSIEKEIENLN 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1980 ALITQKDEELEKLRNEITVLRGEnasAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDE 2059
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESR---LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937

                          810       820       830
                   ....*....|....*....|....*....|...
gi 2024460238 2060 SAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRM 2092
Cdd:TIGR02169  938 DPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1157-1967 8.05e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 8.05e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1157 LSEIETAQADLLKItqeNDALRSSEStllqQLKELQANKDAVdvacQKHIKEREELEHYQKLL-----EENDRVIKDKDD 1231
Cdd:TIGR02168  178 ERKLERTRENLDRL---EDILNELER----QLKSLERQAEKA----ERYKELKAELRELELALlvlrlEELREELEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1232 VIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLA 1311
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1312 NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKI-HLLQEALFASEQRLLA 1390
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAqLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1391 EREELVNENKAVTEKlTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLE 1470
Cdd:TIGR02168  407 ARLERLEDRRERLQQ-EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1471 NAFS------DMKREQELDFSAKRLLVQENTTLKYSIEALEEELK-KKNLENQELIACRSDLSDLLKEAQDARRTLENEL 1543
Cdd:TIGR02168  486 QLQArldsleRLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1544 AAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGE---------------------VENMKENLTVEKKAR--- 1599
Cdd:TIGR02168  566 KQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDlvkfdpklrkalsyllggvlvVDDLDNALELAKKLRpgy 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1600 ---VLDKESFL-------------LERMELQNNIGFLEKEVEEMREKN-------KEFLTEKELLVQEKEKSETKLEEVI 1656
Cdd:TIGR02168  646 rivTLDGDLVRpggvitggsaktnSSILERRREIEELEEKIEELEEKIaelekalAELRKELEELEEELEQLRKELEELS 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1657 KEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIIN 1736
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1737 EEILKEKEKLSKEYYKLHEKvVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLRE----IERLQAQT------FMQ 1806
Cdd:TIGR02168  806 DELRAELTLLNEEAANLRER-LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEleelIEELESELeallneRAS 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1807 KFEADKRAEEVLQTMEKVTKEKDaihQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTkSKELLNLENKKVEE 1886
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELE---SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS-EEYSLTLEEAEALE 960

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1887 LKKEFEALKLAAAQKS--QQLAALQEENVKLAEELgrsrdevtshQKLEEERSVLNNQLLEMKKSLpsNTLRESTlkKEI 1964
Cdd:TIGR02168  961 NKIEDDEEEARRRLKRleNKIKELGPVNLAAIEEY----------EELKERYDFLTAQKEDLTEAK--ETLEEAI--EEI 1026


                   ...
gi 2024460238 1965 DEE 1967
Cdd:TIGR02168 1027 DRE 1029
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1109-2031 1.89e-12

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 73.16  E-value: 1.89e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1109 QDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1188
Cdd:TIGR00606  206 QMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1189 KELQANKDAVDVACQKHIKEREEleHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSI--LTAERDSAQE 1266
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYH--NHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqLQADRHQEHI 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1267 KDLDLKSTHIALKNEIDCLLQ---TNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTK 1343
Cdd:TIGR00606  364 RARDSLIQSLATRLELDGFERgpfSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1344 DNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEK 1423
Cdd:TIGR00606  444 LKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQE 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1424 INELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDE------KKSLENAFSDMKREQ---ELDFSAKRLLVQEN 1494
Cdd:TIGR00606  524 MEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnKKQLEDWLHSKSKEInqtRDRLAKLNKELASL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1495 TTLKYSIEALEEELKKKNLENQELI-------ACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEIL 1567
Cdd:TIGR00606  604 EQNKNHINNELESKEEQLSSYEDKLfdvcgsqDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVC 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1568 NR------ERTELQDKCQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELL 1641
Cdd:TIGR00606  684 QRvfqteaELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRL 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1642 VQEKEKSETKLEEVIKEkmilyketEQLAskiEQLKSDFTSLSVSKAELEDVhscvsvmldelqhkyevtEKEKMELVQE 1721
Cdd:TIGR00606  764 KNDIEEQETLLGTIMPE--------EESA---KVCLTDVTIMERFQMELKDV------------------ERKIAQQAAK 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1722 NESLhaewkSLVIINEEILKEKEKLSKEYYKLHEKVvALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQA 1801
Cdd:TIGR00606  815 LQGS-----DLDRTVQQVNQEKQEKQHELDTVVSKI-ELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEE 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1802 QTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNnLKNEEELTKSKELLNLEN 1881
Cdd:TIGR00606  889 QLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK-VKNIHGYMKDIENKIQDG 967

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1882 KKVEELKKEFEALKLAAaqksqQLAALQEENVKLAEELGRSRDEVTSHQKLEeerSVLNNQLLEMKkslpsntlRESTLK 1961
Cdd:TIGR00606  968 KDDYLKQKETELNTVNA-----QLEECEKHQEKINEDMRLMRQDIDTQKIQE---RWLQDNLTLRK--------RENELK 1031

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1962 kEIDEERASLQKSISDTSalITQKDEELEKLRNEITVLRGENASAKTLQsvvKTLESDKLKLEEKVKNLE 2031
Cdd:TIGR00606 1032 -EVEEELKQHLKEMGQMQ--VLQMKQEHQKLEENIDLIKRNHVLALGRQ---KGYEKEIKHFKKELREPQ 1095
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 642-1243 4.15e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 71.59  E-value: 4.15e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  642 NLKLKQENEKSQHLKEIEALKAKLL----------EVTEEKEQTLENLKAKLESVEDQ------HLVEMEDTLNKLQEAE 705
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNELKnkekelknldKNLNKDEEKINNSNNKIKILEQQikdlndKLKKNKDKINKLNSDL 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  706 IKVK-ELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEgklEIQKLSEQLQAAEKQIQNLETEKVGGSSKV 784
Cdd:TIGR04523  106 SKINsEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEK---ELEKLNNKYNDLKKQKEELENELNLLEKEK 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  785 SNLTKELQGKEQKLLDLEKNLS---AVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSEL 861
Cdd:TIGR04523  183 LNIQKNIDKIKNKLLKLELLLSnlkKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQ 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  862 EQLKSNLtvmETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMK-MNDELRLKERQLEQIQLELTKANEKAVQ 940
Cdd:TIGR04523  263 NKIKKQL---SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKeLKSELKNQEKKLEEIQNQISQNNKIISQ 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  941 LQKNVEQTAQKAEQSQQETLKThQEELKKMQDQLTDMKKQmetsQNQYKDLQAKYEKETSEMITKhdadIKGFKQNLLDA 1020
Cdd:TIGR04523  340 LNEQISQLKKELTNSESENSEK-QRELEEKQNEIEKLKKE----NQSYKQEIKNLESQINDLESK----IQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1021 EEALKAAQKKNDELETQAEELK----KQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQ 1096
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKetiiKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKE 490

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1097 HLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISE---------KSKLLSEIETAQADL 1167
Cdd:TIGR04523  491 LKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDElnkddfelkKENLEKEIDEKNKEI 570

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238 1168 LKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIkdkDDVIQRLQSSYDDL 1243
Cdd:TIGR04523  571 EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKL---SSIIKNIKSKKNKL 643
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 215-275 5.79e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 71.25  E-value: 5.79e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024460238  215 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLF 275
Cdd:COG5244      4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 358-971 7.60e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 71.30  E-value: 7.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  358 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALVRDG-------HDRHVLEMEAKMDQLRAMVEAADREKV 426
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  427 ELLNQLEEekrkvedlQFRVEEESITKGDLERKrQISEDPENVatvseKSRIMELERDLALRVKEVAELRgrlESSKHID 506
Cdd:pfam15921  342 DKIEELEK--------QLVLANSELTEARTERD-QFSQESGNL-----DDQLQKLLADLHKREKELSLEK---EQNKRLW 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  507 DVDTSLSLlqEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENeSLKTKLDHANKENSDVI 586
Cdd:pfam15921  405 DRDTGNSI--TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS-SLTAQLESTKEMLRKVV 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  587 ELWKSKlESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVkldyenemsNLKLKQenekSQHLKEiealkakll 666
Cdd:pfam15921  482 EELTAK-KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV---------DLKLQE----LQHLKN--------- 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  667 evteeKEQTLENLKAKLESVedqhlvemedtlnKLQEAEiKVKELDVLQAKCNEQTKLIGsltQQIRASEEKLLDLAALQ 746
Cdd:pfam15921  539 -----EGDHLRNVQTECEAL-------------KLQMAE-KDKVIEILRQQIENMTQLVG---QHGRTAGAMQVEKAQLE 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  747 KANSEGKLEIQKLS-------EQLQAAEKQIQNLETEKV----GGSSKVSNLTKELQGKEQKLLDLEKNLSAVNqvkdSL 815
Cdd:pfam15921  597 KEINDRRLELQEFKilkdkkdAKIRELEARVSDLELEKVklvnAGSERLRAVKDIKQERDQLLNEVKTSRNELN----SL 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  816 EKELQLLKEKFTSAVDGAE-----------NAQRAMQETINKLNQKE--------------EQFALMSSELEQLKSNLTV 870
Cdd:pfam15921  673 SEDYEVLKRNFRNKSEEMEtttnklkmqlkSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQSKIQF 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  871 METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLmkmnDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ 950
Cdd:pfam15921  753 LEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          650       660
                   ....*....|....*....|.
gi 2024460238  951 KAEQSQQETLKTHQEELKKMQ 971
Cdd:pfam15921  829 RQEQESVRLKLQHTLDVKELQ 849
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 462-1229 2.56e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 69.48  E-value: 2.56e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  462 ISEDPENVATVSEKSRiMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMaaagKEHQREMSSLKE 541
Cdd:pfam12128  205 ILEDDGVVPPKSRLNR-QQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGY----KSDETLIASRQE 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  542 KFESSEEALRKEIKTLSAS-NERMGKENESLKT-KLDHANKENS-DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQ 618
Cdd:pfam12128  280 ERQETSAELNQLLRTLDDQwKEKRDELNGELSAaDAAVAKDRSElEALEDQHGAFLDADIETAAADQEQLPSWQSELENL 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  619 TAEFAELKTQMEKVKLDYENEMSNLKlkqenekSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTL 698
Cdd:pfam12128  360 EERLKALTGKHQDVTAKYNRRRSKIK-------EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGK 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  699 NKLQEAEIKVK----ELDVLQAkcneqtkligsltqQIRASEEKLLDLAALQKansegklEIQKLSEQLQAAEKQIQNLE 774
Cdd:pfam12128  433 LEFNEEEYRLKsrlgELKLRLN--------------QATATPELLLQLENFDE-------RIERAREEQEAANAEVERLQ 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  775 TEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS--------LEKELQLLKEKFTSAVDGA-----------EN 835
Cdd:pfam12128  492 SELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPqagtllhfLRKEAPDWEQSIGKVISPEllhrtdldpevWD 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  836 AQRAMQETINKLNQKEEQFALMSSEL--EQLKSNLTVMETKLKEREEREQQLTEAKVKLendiaeimkssgdsSAQLMKM 913
Cdd:pfam12128  572 GSVGGELNLYGVKLDLKRIDVPEWAAseEELRERLDKAEEALQSAREKQAAAEEQLVQA--------------NGELEKA 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  914 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMetsQNQYKDLQA 993
Cdd:pfam12128  638 SREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQ---KEQKREART 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  994 KYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKkndELETQ-AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDL 1072
Cdd:pfam12128  715 EKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELK---ALETWyKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRR 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1073 ISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDreeLWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISE 1152
Cdd:pfam12128  792 QEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQ---LARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCE 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1153 KSKLLSeietaqadlLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHI---------KEREEL-EHYQKlLEEN 1222
Cdd:pfam12128  869 MSKLAT---------LKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVehfknviadHSGSGLaETWES-LREE 938


                   ....*..
gi 2024460238 1223 DRVIKDK 1229
Cdd:pfam12128  939 DHYQNDK 945
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 630-1172 4.34e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 68.51  E-value: 4.34e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  630 EKVKLDYENEmsnlKLKQENEKSQHLKEIEALKAKLLEvteeKEQTLENLKAKlesveDQHLVEMEDTLNKLQEAEIKVK 709
Cdd:TIGR04523  165 KKQKEELENE----LNLLEKEKLNIQKNIDKIKNKLLK----LELLLSNLKKK-----IQKNKSLESQISELKKQNNQLK 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  710 E-LDVLQAKCNEQTKLIGSLTQQIRASEEKLLD----LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKv 784
Cdd:TIGR04523  232 DnIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK- 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  785 sNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQL 864
Cdd:TIGR04523  311 -ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  865 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKN 944
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  945 VEQTAQKAEQSQQeTLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyEKETSEMITKHDADIKGFKQNLLDAEEAL 1024
Cdd:TIGR04523  470 LKVLSRSINKIKQ-NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK-ISSLKEKIEKLESEKKEKESKISDLEDEL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1025 KA--AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIElmsdkmrDLISEKETlaqerntlklEKESLLSQHLEMES 1102
Cdd:TIGR04523  548 NKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ-------ELIDQKEK----------EKKDLIKEIEEKEK 610

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1103 KILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQ 1172
Cdd:TIGR04523  611 KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIE 680
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
342-901 6.16e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.17  E-value: 6.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  342 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVrDGHDRHVLEMEAKMDQLRAMVEAA 421
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  422 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENvaTVSEKSRIMELERDLALRVKEVAELRGRLES 501
Cdd:PRK03918   258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE--YLDELREIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  502 SKhiddvdtslsllQEISSLQEKMaaagKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKE 581
Cdd:PRK03918   336 KE------------ERLEELKKKL----KELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKA 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  582 NSDvIELWKSKLESAIASHQQAMEELKVSFNKgvgaqtAEFAELKTQMEKVKLDYENEmsnlklkqENEKSQHLKEIEAL 661
Cdd:PRK03918   400 KEE-IEEEISKITARIGELKKEIKELKKAIEE------LKKAKGKCPVCGRELTEEHR--------KELLEEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  662 KAKLLEvTEEKEQTLENLKAKLESV--EDQHLVEMEDTLNKLQEAEIKVKELDV--LQAKCNEQTKL---IGSLTQQIRA 734
Cdd:PRK03918   465 EKELKE-IEEKERKLRKELRELEKVlkKESELIKLKELAEQLKELEEKLKKYNLeeLEKKAEEYEKLkekLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  735 SEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVggsSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS 814
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV---EELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  815 LEKELQLLKEKFtSAVDGAENAQRAMQETINKLNQK--EEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKL 892
Cdd:PRK03918   621 LKKLEEELDKAF-EELAETEKRLEELRKELEELEKKysEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699


                   ....*....
gi 2024460238  893 ENDIAEIMK 901
Cdd:PRK03918   700 KEELEEREK 708
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 431-1272 6.32e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.07  E-value: 6.32e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  431 QLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHiddvDT 510
Cdd:pfam02463  170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ----EL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  511 SLSLLQEISSLQEKMAAAGKEHQREMSSLKEkfESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWK 590
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKE--EEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEK 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  591 SKLESAIASHQQAMEELKVSfNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQEnEKSQHLKEIEALKAKLLEVTE 670
Cdd:pfam02463  324 KKAEKELKKEKEEIEELEKE-LKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK-LESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  671 EKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEiKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANS 750
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEE-ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  751 EGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAV 830
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  831 DGAENAQRAMQETINKLNQKEE--QFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGD--- 905
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLliPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLkes 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  906 -----SSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQS--QQETLKTHQEELKKMQDQLTDMK 978
Cdd:pfam02463  641 akakeSGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILrrQLEIKKKEQREKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  979 KQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASA 1058
Cdd:pfam02463  721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1059 RKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELN---SENKKILKQKEAA 1135
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITkeeLLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1136 EAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHY 1215
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460238 1216 QKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEvsILTAERDSAQEKDLDLK 1272
Cdd:pfam02463  961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKE--RLEEEKKKLIRAIIEET 1015
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1320-1998 7.12e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.84  E-value: 7.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1320 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE---ASNSEKIHLLQEALFASEQRLLAEREELV 1396
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmlEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1397 NENKAVTEKLTKATADAVL----AETAFTEKINELNLEKESVFSKSLQFEKHNEALlreKDELERKYSELLDEKKS-LEN 1471
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMhfrsLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDrIEQ 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1472 AFSDMKRE-QELDFSAKRLLVQENTtLKYSIEALEEELKKKN-LENQELIACRSDLSDLLKEAQDARRTLENELAAVSHA 1549
Cdd:pfam15921  272 LISEHEVEiTGLTEKASSARSQANS-IQSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1550 KQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKA-------------------RVLDKESFLLER 1610
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhlrRELDDRNMEVQR 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1611 MEL------QNNIGFLEKEVEEMREKNKEFLTEKELLVQ---EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1681
Cdd:pfam15921  431 LEAllkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1682 SLSVSKAELEDVHSCVSVMLDELQHKYevTEKEKMELVQ---ENESLHAEWKSLVIineEILKEKEKLSKEYYKLHEKVV 1758
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLK--NEGDHLRNVQtecEALKLQMAEKDKVI---EILRQQIENMTQLVGQHGRTA 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1759 ALLEQTDADFSCRLlvseGKHELLLEEMSNLA----LKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqe 1834
Cdd:pfam15921  586 GAMQVEKAQLEKEI----NDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1835 kietLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE-ELKK-----------EFEALKLAAAQKS 1902
Cdd:pfam15921  659 ----LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQtrntlksmegsDGHAMKVAMGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1903 Q------QLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLNNQL-------------LEMKKSlPSNTLRESTLKKE 1963
Cdd:pfam15921  735 QitakrgQIDALQSKIQFLEEAMTNANKE---KHFLKEEKNKLSQELstvateknkmageLEVLRS-QERRLKEKVANME 810

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2024460238 1964 IDEERASLQksISDTSALITQKDEELEKLRNEITV 1998
Cdd:pfam15921  811 VALDKASLQ--FAECQDIIQRQEQESVRLKLQHTL 843
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1740-2039 8.02e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 8.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1740 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQ 1819
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEEL---------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1820 TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAA 1899
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1900 QKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTS 1979
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1980 ALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSE 2039
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 942-1519 9.81e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.35  E-value: 9.81e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  942 QKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQaKYEKETSEMITKHDADIKGFKQNLLDAE 1021
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILE-QQIKDLNDKLKKNKDKINKLNSDLSKIN 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1022 EALKAAQKKNDELETQAEELKKQAEQAKSL----SSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQH 1097
Cdd:TIGR04523  110 SEIKNDKEQKNKLEVELNKLEKQKKENKKNidkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1098 LEMESKILLVQQDREELWTKNEELNSENKKILKQKEaaeaKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDAL 1177
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKK----QNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1178 RSSESTLLQQLKELQANKDAVDVACQKHIKEREEL--EHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVS 1255
Cdd:TIGR04523  266 KKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLnnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1256 ILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETER 1335
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1336 EKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEalfaseqrlLAEREELVNENKAVTEKLTKATADAVL 1415
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ---------LKVLSRSINKIKQNLEQKQKELKSKEK 496

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1416 AETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRL--LVQE 1493
Cdd:TIGR04523  497 ELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIeeLKQT 576

                          570       580
                   ....*....|....*....|....*.
gi 2024460238 1494 NTTLKYSIEALEEELKKKNLENQELI 1519
Cdd:TIGR04523  577 QKSLKKKQEEKQELIDQKEKEKKDLI 602
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
720-1236 1.06e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  720 EQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLL 799
Cdd:PRK03918   197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  800 DLEKNLSAVNQVKDSLEK--ELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKE 877
Cdd:PRK03918   277 ELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  878 REEREQQLTEAKVKLENdIAEIMKSSGDSSAQlmKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQ- 956
Cdd:PRK03918   357 LEERHELYEEAKAKKEE-LERLKKRLTGLTPE--KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKk 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  957 ---------QETLKTHQEEL-KKMQDQLTDMKKQMETSQNQYKDLQAkyEKETSEMITKHDADIKGFKQNLLDAEEALKA 1026
Cdd:PRK03918   434 akgkcpvcgRELTEEHRKELlEEYTAELKRIEKELKEIEEKERKLRK--ELRELEKVLKKESELIKLKELAEQLKELEEK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1027 AQKKN-DELETQAEELKKQAEQAKSLS---SVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESL-LSQHLEME 1101
Cdd:PRK03918   512 LKKYNlEELEKKAEEYEKLKEKLIKLKgeiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgFESVEELE 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1102 SKIllvqQDREELWTKNEELnSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEND------ 1175
Cdd:PRK03918   592 ERL----KELEPFYNEYLEL-KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyeelre 666

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024460238 1176 ---ALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRL 1236
Cdd:PRK03918   667 eylELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKV 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 796-1012 1.44e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 65.56  E-value: 1.44e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  796 QKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKL 875
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  876 KEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN--------------DELRLKERQLEQIQLELTKANEKAVQL 941
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLqylkylaparreqaEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024460238  942 QKNVEQ---TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKG 1012
Cdd:COG4942    180 LAELEEeraALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1207-2035 2.67e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.24  E-value: 2.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1207 KEREELEHYQKLLEENDRVIKDKDDVIQRLQSsyddlarnqrellqevsiltaERDSAqEKDLDLKSTHIalKNEIDCLL 1286
Cdd:TIGR02169  174 KALEELEEVEENIERLDLIIDEKRQQLERLRR---------------------EREKA-ERYQALLKEKR--EYEGYELL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1287 QTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNM-DLKASLSSLSNFLEEMKSS 1365
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERS 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1366 REASNSEKIHLLQEA--LFASEQRLLAEREEL---VNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQ 1440
Cdd:TIGR02169  310 IAEKERELEDAEERLakLEAEIDKLLAEIEELereIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1441 FEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELK----KKNLENQ 1516
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEqlaaDLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1517 ELIACRSDLSDLLKEAQDARRtlenELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLtGEVE---------- 1586
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQR----ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQL-GSVGeryataieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1587 --NMKENLTVEK-----------KARVLDKESFL-----------LERMELQNNIGFLEKEVEEMREKNKEFL------- 1635
Cdd:TIGR02169  545 agNRLNNVVVEDdavakeaiellKRRKAGRATFLplnkmrderrdLSILSEDGVIGFAVDLVEFDPKYEPAFKyvfgdtl 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1636 ------TEKELLVQ-----------EKEKSET----KLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvh 1694
Cdd:TIGR02169  625 vvedieAARRLMGKyrmvtlegelfEKSGAMTggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN-- 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1695 scvsvMLDELQHKYEVTEKEKMELVQENESLHAEwkslviinEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLlv 1774
Cdd:TIGR02169  703 -----RLDELSQELSDASRKIGEIEKEIEQLEQE--------EEKLKERLEELEEDLSSLEQEIENVKSELKELEARI-- 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1775 segkhELLLEEMSNLALKLREIERLQAQTFMQKFEADKRA-EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQ 1853
Cdd:TIGR02169  768 -----EELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1854 NELDMLKQNNLKNEEELtkskellnleNKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLE 1933
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENL----------NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI---EELE 909

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1934 EERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEEraslqKSISDTSALITQKDEELEKLRNEITVLRGENASA------- 2006
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGED-----EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAiqeyeev 984

                          890       900       910
                   ....*....|....*....|....*....|...
gi 2024460238 2007 ----KTLQSVVKTLESDKLKLEEKVKNLEQKLK 2035
Cdd:TIGR02169  985 lkrlDELKEKRAKLEEERKAILERIEEYEKKKR 1017
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 823-1640 2.71e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 2.71e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  823 KEKFTSAVDGAENAQRAMQETINKLNQ-KEEQFALMSSELEQLKSNLTVMETK------LKEREEREQQltEAKVKLEND 895
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNElHEKQKFYLRQSVIDLQTKLQEMQMErdamadIRRRESQSQE--DLRNQLQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  896 IAEI----------MKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQ-QETLKTHQ 964
Cdd:pfam15921  151 VHELeaakclkedmLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAiSKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  965 EELKKMQDQLTDMKKQMET----SQNQYKDLQAKYEKETSEMITKHDADIKGFKqnlldaeEALKAAQKKNDELETQAEE 1040
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEAlkseSQNKIELLLQQHQDRIEQLISEHEVEITGLT-------EKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1041 LKKQAEQAKSLSsvlasarkeielmsdkMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1120
Cdd:pfam15921  304 IQEQARNQNSMY----------------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQ 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1121 LNSENKKILKQKEAAEAKSRQESTEkVALISEKSKLLSEIETAQADLLkitqenDALRSSESTLLQQLKELQANKDAVDV 1200
Cdd:pfam15921  368 FSQESGNLDDQLQKLLADLHKREKE-LSLEKEQNKRLWDRDTGNSITI------DHLRRELDDRNMEVQRLEALLKAMKS 440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1201 ACQKHIKER--------EELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQREllqeVSILTAerdSAQEKDLDLK 1272
Cdd:pfam15921  441 ECQGQMERQmaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT----VSDLTA---SLQEKERAIE 513

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1273 STH---IALKNEIDCLLQTNRSLQSEKEmllksreelcvSLANTANENQALKLRKDEMQTELETEREKLEKMTKdnmdlk 1349
Cdd:pfam15921  514 ATNaeiTKLRSRVDLKLQELQHLKNEGD-----------HLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ------ 576

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1350 aslsslsnFLEEMKSSREASNSEKIHLLQEalfASEQRLlaEREELvnenkavteKLTKATADAVLAEtaFTEKINELNL 1429
Cdd:pfam15921  577 --------LVGQHGRTAGAMQVEKAQLEKE---INDRRL--ELQEF---------KILKDKKDAKIRE--LEARVSDLEL 632

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1430 EKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR-----EQELDFSAKRL----------LVQEN 1494
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnkSEEMETTTNKLkmqlksaqseLEQTR 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1495 TTLKySIEALEEELKKKNLENQELIACRSDLSDLLkeaQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTEL 1574
Cdd:pfam15921  713 NTLK-SMEGSDGHAMKVAMGMQKQITAKRGQIDAL---QSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238 1575 QDKCQKLTGEVENMKENLTVEKKArvLDKESflLERMELQNNIGflEKEVEEMREKNKEFLTEKEL 1640
Cdd:pfam15921  789 AGELEVLRSQERRLKEKVANMEVA--LDKAS--LQFAECQDIIQ--RQEQESVRLKLQHTLDVKEL 848
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1621-2035 3.53e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 3.53e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1621 EKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM 1700
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1701 LDELQHKYEVTEkEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQtdadfscrllvsegkhe 1780
Cdd:PRK03918   268 IEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER----------------- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1781 llLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLaslensrqtnEKLQNELDMLK 1860
Cdd:PRK03918   330 --IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----------EKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1861 QNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEEN-----VKLAEELGRSRDEVtshQKLEEE 1935
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKEL---KEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1936 RSVLNNQLLEMKKSLpSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2015
Cdd:PRK03918   475 ERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          410       420
                   ....*....|....*....|
gi 2024460238 2016 LESDKLKLEEKVKNLEQKLK 2035
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELA 573
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 61-122 4.18e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 65.09  E-value: 4.18e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238   61 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRP 122
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1784-2038 4.52e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 4.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1784 EEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNN 1863
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1864 LKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK-----------L 1932
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNeierlearlerL 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1933 EEERSVLNNQLLEMKKSLPSNTLRE-STLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQS 2011
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          250       260
                   ....*....|....*....|....*..
gi 2024460238 2012 VVKTLESDKLKLEEKVKNLEQKLKAKS 2038
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSGLS 519
PTZ00121 PTZ00121
MAEBL; Provisional
 345-1169 5.08e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.16  E-value: 5.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  345 ARKISGTTALQEALKE-----KQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvRDGHDRHVLEMEAKMDQLRamvE 419
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDaeeakKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAK---K 1297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  420 AADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERdlALRVKEVAELRgrl 499
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA--AEEKAEAAEKK--- 1372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  500 esskhiddvdtslsllqeiSSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTlsasnermgKENESLKTKLDHAN 579
Cdd:PTZ00121  1373 -------------------KEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL---------KKAAAAKKKADEAK 1424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  580 KEnsdvielwksklesaiASHQQAMEELKvsfnkgvgaqtaefaelKTQMEKVKLDYENEMSNLKLKQENEKSqhlKEIE 659
Cdd:PTZ00121  1425 KK----------------AEEKKKADEAK-----------------KKAEEAKKADEAKKKAEEAKKAEEAKK---KAEE 1468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  660 ALKAKLLEVTEEKEQTLENLKAKLESVEDQhlvemEDTLNKLQEAEIKVKELdvlqAKCNEQTKligslTQQIRASEEKl 739
Cdd:PTZ00121  1469 AKKADEAKKKAEEAKKADEAKKKAEEAKKK-----ADEAKKAAEAKKKADEA----KKAEEAKK-----ADEAKKAEEA- 1533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  740 ldlaalQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKnlSAVNQVKDSLEKEL 819
Cdd:PTZ00121  1534 ------KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE--ARIEEVMKLYEEEK 1605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  820 QLLKEKFTSAVDGAENAQRAMQE-----TINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEN 894
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKAeeekkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  895 D---IAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtlktHQEELKKMQ 971
Cdd:PTZ00121  1686 DekkAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD----EEEKKKIAH 1761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  972 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKK-NDELETQAEELKkqaEQAKS 1050
Cdd:PTZ00121  1762 LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLViNDSKEMEDSAIK---EVADS 1838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1051 LSSVLASArKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILK 1130
Cdd:PTZ00121  1839 KNMQLEEA-DAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDD 1917

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 2024460238 1131 QKEAAEAKSR--QESTEKVALISEKSKLLSEIETAQADLLK 1169
Cdd:PTZ00121  1918 KLDKDEYIKRdaEETREEIIKISKKDMCINDFSSKFCDYMK 1958
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1184-1732 6.64e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 6.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1184 LLQQLKELQANKDAVDVACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDS 1263
Cdd:COG1196    237 LEAELEELEAELEELEAELEELEAELAELE---AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1264 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTK 1343
Cdd:COG1196    314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1344 DNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEalfasEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEK 1423
Cdd:COG1196    394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEA-----LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1424 INELNLEKESVfskslqfekhnEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAK-----RLLVQENTTLK 1498
Cdd:COG1196    469 LEEAALLEAAL-----------AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlagavAVLIGVEAAYE 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1499 YSIEALEEELKKKNLENQELIAcrSDLSDLLKEAQDARRTL-------ENELAAVSHAKQVLSSSFNTCSSDIEILNRER 1571
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVA--AAAIEYLKAAKAGRATFlpldkirARAALAAALARGAIGAAVDLVASDLREADARY 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1572 TELQDKCQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNNigflEKEVEEMREKNKEFLTEKELLVQEKEKSETK 1651
Cdd:COG1196    616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTGGSRRELLAALLEAEAELEELAERLAEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1652 LEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKS 1731
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771


                   .
gi 2024460238 1732 L 1732
Cdd:COG1196    772 L 772
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1290-1876 8.58e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.31  E-value: 8.58e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1290 RSLQSEKEMLLKSREELCVSLANTANenqaLKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREAS 1369
Cdd:PRK03918   165 KNLGEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1370 NSEKIHLLQ-EALFASEQRLLAEREELVNENKAVTEKLT---------KATADAVLAETAFTEKINELNLEKESVFSKSL 1439
Cdd:PRK03918   241 EELEKELESlEGSKRKLEEKIRELEERIEELKKEIEELEekvkelkelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1440 QFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENttlKYSIEALEEELKKKNLENQELI 1519
Cdd:PRK03918   321 EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELE---RLKKRLTGLTPEKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1520 ACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSsdieILNRERTELQDK--CQKLTGEVENMKENL-TVEK 1596
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCP----VCGRELTEEHRKelLEEYTAELKRIEKELkEIEE 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1597 KARVLDKESFLLER-MELQNNIGFLEKEVEEMREKNKEFlteKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQ 1675
Cdd:PRK03918   474 KERKLRKELRELEKvLKKESELIKLKELAEQLKELEEKL---KKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1676 LKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLhE 1755
Cdd:PRK03918   551 LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-D 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1756 KVVALLEQTDADF-SCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhQE 1834
Cdd:PRK03918   630 KAFEELAETEKRLeELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER-EK 708

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2024460238 1835 KIETLASLENSRQTNEKLQNELDMLKqnNLKNEEELTKSKEL 1876
Cdd:PRK03918   709 AKKELEKLEKALERVEELREKVKKYK--ALLKERALSKVGEI 748
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
631-1160 8.73e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.31  E-value: 8.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  631 KVKLDYENEMSNLK--LKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKV 708
Cdd:PRK03918   169 EVIKEIKRRIERLEkfIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKE-VKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  709 ----KELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQ-----------------KANSEGKLEIQKLSEQLQAAE 767
Cdd:PRK03918   248 esleGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKekaeeyiklsefyeeylDELREIEKRLSRLEEEINGIE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  768 KQIQNLETEKvggsSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKdSLEKELQLLKEKFT--------SAVDGAENAQRA 839
Cdd:PRK03918   328 ERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKRLTgltpekleKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  840 MQETINKLNQKEEQFALMSSEL----EQLKS--------------------------NLTVMETKLKEREEREQQLTEAK 889
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELkkaiEELKKakgkcpvcgrelteehrkelleeytaELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  890 VKLENDIAEIMKSSgdssaQLMKMNDELRLKERQLEQIQLELTKANEKavqLQKNVEQTAQKAEqSQQETLKTHQEELKK 969
Cdd:PRK03918   483 RELEKVLKKESELI-----KLKELAEQLKELEEKLKKYNLEELEKKAE---EYEKLKEKLIKLK-GEIKSLKKELEKLEE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  970 MQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIK---GFKQNLLDAEEALKAAQKKNDELETQAEELKKQAE 1046
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKelePFYNEYLELKDAEKELEREEKELKKLEEELDKAFE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1047 QAKSLSSVLASARKEIELMS-----DKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEEL 1121
Cdd:PRK03918   634 ELAETEKRLEELRKELEELEkkyseEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL 713

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 2024460238 1122 NSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEI 1160
Cdd:PRK03918   714 EKLEKALERVEELREKVKKYKALLKERALSKVGEIASEI 752
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
513-1089 2.39e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 2.39e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  513 SLLQEISSLQEKMAAAGKEHQrEMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIEL---- 588
Cdd:PRK03918   211 EISSELPELREELEKLEKEVK-ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkelk 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  589 WKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVkldyeNEMSNLKLKQENEKSQHLKEIEALK--AKLL 666
Cdd:PRK03918   290 EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL-----EEKEERLEELKKKLKELEKRLEELEerHELY 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  667 EVTEEKEQTLENLKAKLESVEdqhlveMEDTLNKLQEAEIKVKELdvlQAKCNEQTKLIGSLTQQIrasEEKLLDLAALQ 746
Cdd:PRK03918   365 EEAKAKKEELERLKKRLTGLT------PEKLEKELEELEKAKEEI---EEEISKITARIGELKKEI---KELKKAIEELK 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  747 KANSEGKLEIQKLSEQlqaAEKQIQNLETEKVggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVkdsLEKELQLLKEKf 826
Cdd:PRK03918   433 KAKGKCPVCGRELTEE---HRKELLEEYTAEL------KRIEKELKEIEEKERKLRKELRELEKV---LKKESELIKLK- 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  827 tSAVDGAENAQRAMQE-TINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGD 905
Cdd:PRK03918   500 -ELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKE 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  906 SSAQLMKMNDELRLKERQLEQIQLELTKAnekavqlqknveQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ 985
Cdd:PRK03918   579 LEELGFESVEELEERLKELEPFYNEYLEL------------KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELR 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  986 NQYKDLQAKYEKETSEMItkhdadikgfKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELM 1065
Cdd:PRK03918   647 KELEELEKKYSEEEYEEL----------REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKL 716

                          570       580
                   ....*....|....*....|....
gi 2024460238 1066 SDKMRDLISEKETLAQERNTLKLE 1089
Cdd:PRK03918   717 EKALERVEELREKVKKYKALLKER 740
PLN02939 PLN02939
transferase, transferring glycosyl groups
 652-982 2.61e-09

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 62.61  E-value: 2.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  652 SQHLKEIEALKAKLLEVTEEKEQ----TLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQakcneqtkligs 727
Cdd:PLN02939   102 MQRDEAIAAIDNEQQTNSKDGEQlsdfQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQ------------ 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  728 ltQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLqaaEKQIQNLETEKVGGSSKVSNLTKELQgkeqkLLDLEkNLSa 807
Cdd:PLN02939   170 --GKINILEMRLSETDARIKLAAQEKIHVEILEEQL---EKLRNELLIRGATEGLCVHSLSKELD-----VLKEE-NML- 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  808 vnqvkdsLEKELQLLKEKFTSavdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTE 887
Cdd:PLN02939   238 -------LKDDIQFLKAELIE-----------VAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWW 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  888 AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQiqlELTKAN------EKAVQLQKNVEQTAQKAEQSQQET-- 959
Cdd:PLN02939   300 EKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEA---SLKEANvskfssYKVELLQQKLKLLEERLQASDHEIhs 376

                          330       340
                   ....*....|....*....|....
gi 2024460238  960 -LKTHQEELKKMQDQLTDMKKQME 982
Cdd:PLN02939   377 yIQLYQESIKEFQDTLSKLKEESK 400
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 507-1229 3.66e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 62.05  E-value: 3.66e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  507 DVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKfESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVI 586
Cdd:pfam05483   69 DFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQK-ENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLI 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  587 E------LWKSKLESAIAS----------HQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYenemsNLKLKQENE 650
Cdd:pfam05483  148 KennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEM-----HFKLKEDHE 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  651 KSQHLKEiealkaKLLEVTEEKEQTLENLKAKLESVEDQhlveMEDTLNKLQEAEIKVKELDvlqakcnEQTKLIGSLTQ 730
Cdd:pfam05483  223 KIQHLEE------EYKKEINDKEKQVSLLLIQITEKENK----MKDLTFLLEESRDKANQLE-------EKTKLQDENLK 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  731 QIRASEEKLLDLAALQKANSEGKLEIQK-LSEQLQAAEKQIQNLETEKvggSSKVSNLTKELQGKEQKLLDLEKNLSAVN 809
Cdd:pfam05483  286 ELIEKKDHLTKELEDIKMSLQRSMSTQKaLEEDLQIATKTICQLTEEK---EAQMEELNKAKAAHSFVVTEFEATTCSLE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  810 QVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEeqfalmsSELEQLKSNLTVMETKLKEREEREQQLTEAK 889
Cdd:pfam05483  363 ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKE-------VELEELKKILAEDEKLLDEKKQFEKIAEELK 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  890 VKLENDIAEIM---KSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQET------L 960
Cdd:pfam05483  436 GKEQELIFLLQareKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEAsdmtleL 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  961 KTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHD---ADIKGFKQNLLDAEEALKAAQKKNDELETQ 1037
Cdd:pfam05483  516 KKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDevkCKLDKSEENARSIEYEVLKKEKQMKILENK 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1038 AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETlaqERNTLKLEKESLLSQHLEM----ESKILLVQQDREE 1113
Cdd:pfam05483  596 CNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEI---KVNKLELELASAKQKFEEIidnyQKEIEDKKISEEK 672

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1114 LWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS----KLLSEIETAQADLLKITQENDALRSSESTLLQQLK 1189
Cdd:pfam05483  673 LLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKhqydKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIK 752

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 2024460238 1190 -ELQANKDAVDVacqkhikEREELEHYQKLLEENDRVIKDK 1229
Cdd:pfam05483  753 aELLSLKKQLEI-------EKEEKEKLKMEAKENTAILKDK 786
PTZ00121 PTZ00121
MAEBL; Provisional
 878-1512 3.92e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 3.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  878 REEREQQLTEAKVKLEND--IAEIMKSSGDSSAQLMKMNDELRLKE----RQLEQIQLELTKANEKAVQLQKNVEQTAQK 951
Cdd:PTZ00121  1194 RKAEDARKAEAARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAeeakKAEEERNNEEIRKFEEARMAHFARRQAAIK 1273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  952 AEQSQQETLKTHQEELKKMQDqltdMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKN 1031
Cdd:PTZ00121  1274 AEEARKADELKKAEEKKKADE----AKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAK 1349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1032 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKEtlAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1111
Cdd:PTZ00121  1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE--AKKKAEEDKKKADELKKAAAAKKKADEAKKKA 1427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1112 EELwTKNEELnseNKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTllqQLKEL 1191
Cdd:PTZ00121  1428 EEK-KKADEA---KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA---KKKAD 1500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1192 QANKDAVDVACQKHIKEREELEHYQKLLEENDRviKDKDDVIQRLQSSYDDLARNQREL--LQEVSILTAERDSAQEKDL 1269
Cdd:PTZ00121  1501 EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA--KKADEAKKAEEKKKADELKKAEELkkAEEKKKAEEAKKAEEDKNM 1578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1270 DLKSTHIALKNEidcllqtnrslqsekemllKSREELCVSLANTANENQALKLRKDemqtelETEREKLEKMTKDNMDLK 1349
Cdd:PTZ00121  1579 ALRKAEEAKKAE-------------------EARIEEVMKLYEEEKKMKAEEAKKA------EEAKIKAEELKKAEEEKK 1633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1350 ASLSSLSNFLEEMKSSREASNSEKIHLLQealfASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNL 1429
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIK----AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1430 EKESVFSKSLQFEKHNEALLREKDELERKYSElldEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELK 1509
Cdd:PTZ00121  1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEE---DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786


                   ...
gi 2024460238 1510 KKN 1512
Cdd:PTZ00121  1787 EED 1789
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
801-996 4.92e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 61.57  E-value: 4.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  801 LEKNLSAVNQVKDSLEKELQLLKEKftsaVDGAENAQRAMQETiNKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 880
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKE----LEEAEAALEEFRQK-NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  881 REQQLTEAKVKLENDIAEIMkssgdSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVE-------------- 946
Cdd:COG3206    241 RLAALRAQLGSGPDALPELL-----QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAalraqlqqeaqril 315

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  947 -------QTAQKAEQSQQETLKTHQEELKKM---QDQLTDMKKQMETSQNQYKDLQAKYE 996
Cdd:COG3206    316 asleaelEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELYESLLQRLE 375
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 618-1591 5.29e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 61.99  E-value: 5.29e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  618 QTAEFAELKTQMEKVKLDY-----ENEMSNLKLKQENEKSQHLKEI----EALKAKLLEVTEEKEQTLENLKAKLESVED 688
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQgqkvqEHQMELKYLKQYKEKACEIRDQitskEAQLESSREIVKSYENELDPLKNRLKEIEH 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  689 Q--HLVEMEDTLNKLQEAEIKVKeldvlqakcNEQTKLIGSLTQQIRASEEKLLDLAALQKAnsegklEIQKLSEQLQAA 766
Cdd:TIGR00606  260 NlsKIMKLDNEIKALKSRKKQME---------KDNSELELKMEKVFQGTDEQLNDLYHNHQR------TVREKERELVDC 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  767 EKQIQNLETEKVGGSSKVSNLTKElQGKEQklldleknLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 846
Cdd:TIGR00606  325 QRELEKLNKERRLLNQEKTELLVE-QGRLQ--------LQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNF 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  847 LNQKEEQFALMSSELEQLKSNLTvmetklkereEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 926
Cdd:TIGR00606  396 HTLVIERQEDEAKTAAQLCADLQ----------SKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQ 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  927 IQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLtDMKKQMETSQNQYKDLQAKYEKETsEMITKH 1006
Cdd:TIGR00606  466 LEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADL-DRKLRKLDQEMEQLNHHTTTRTQM-EMLTKD 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1007 DADikgfkqnllDAEEALKAAQKKNDELETQAEELKKQaeqaKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL 1086
Cdd:TIGR00606  544 KMD---------KDEQIRKIKSRHSDELTSLLGYFPNK----KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHI 610

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1087 KLEKESLLSQHLEMESKILlvqqdrEELWTKNEELNSENKKilkqkeaaeaKSRQESTEKVALISEKSKLLSEIETaqad 1166
Cdd:TIGR00606  611 NNELESKEEQLSSYEDKLF------DVCGSQDEESDLERLK----------EEIEKSSKQRAMLAGATAVYSQFIT---- 670

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1167 llKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARN 1246
Cdd:TIGR00606  671 --QLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPE 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1247 QRELLQEVSILTAERDSAQEKDLDLKSThIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLAnTANENQALKLRKDE 1326
Cdd:TIGR00606  749 LRNKLQKVNRDIQRLKNDIEEQETLLGT-IMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQA-AKLQGSDLDRTVQQ 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1327 MQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEAlfaseQRLLAEREELVNENKAVTEkL 1406
Cdd:TIGR00606  827 VNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNL-----QRRQQFEEQLVELSTEVQS-L 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1407 TKATADAVLAETAFTEKINELNLEKESVFSKSlqfEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQeldfsa 1486
Cdd:TIGR00606  901 IREIKDAKEQDSPLETFLEKDQQEKEELISSK---ETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDY------ 971

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1487 krlLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSdllkEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEI 1566
Cdd:TIGR00606  972 ---LKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDID----TQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEM 1044

                          970       980
                   ....*....|....*....|....*
gi 2024460238 1567 LNRERTELQDKCQKLTGEVENMKEN 1591
Cdd:TIGR00606 1045 GQMQVLQMKQEHQKLEENIDLIKRN 1069
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1137-1934 7.24e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1137 AKSRQESTEKVALISEKSkllSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDvACQKHIKEREELEHYQ 1216
Cdd:TIGR02169  152 PVERRKIIDEIAGVAEFD---RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1217 KL--LEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKS-THIALKNEIDCLLQTNRSLQ 1293
Cdd:TIGR02169  228 LLkeKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLE 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1294 SEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEM----KSSREAS 1369
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkefAETRDEL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1370 NSEKIHLlqEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALL 1449
Cdd:TIGR02169  388 KDYREKL--EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE----AKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1450 REKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKK--------KNLENQELIAC 1521
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlGSVGERYATAI 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1522 RSDLS------------------DLLKEAQDARRTL--------ENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQ 1575
Cdd:TIGR02169  542 EVAAGnrlnnvvveddavakeaiELLKRRKAGRATFlplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFG 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1576 DkcqklTGEVENMKENLTVEKKARVLDKESFLLER-----------MELQNNIGFLEKEVEEMREKNKEFLTEKELLVQE 1644
Cdd:TIGR02169  622 D-----TLVVEDIEAARRLMGKYRMVTLEGELFEKsgamtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1645 KEK--------------SETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvhscvsvMLDELQHKYEV 1710
Cdd:TIGR02169  697 LRRienrldelsqelsdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS-------ELKELEARIEE 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1711 TEKEKMELVQENESLHAEwkslviINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLvsegKHELLLEEMSNLA 1790
Cdd:TIGR02169  770 LEEDLHKLEEALNDLEAR------LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL----EKEYLEKEIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1791 LKLREIErlqaqtfmqkfeaDKRAEevlqtmekVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEEL 1870
Cdd:TIGR02169  840 EQRIDLK-------------EQIKS--------IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL 898

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024460238 1871 TKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEE 1934
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQR 962
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 336-1219 8.06e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 61.34  E-value: 8.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  336 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERA-------EVAKATSHVGEIEQELALVRDGHDRHVLEME 408
Cdd:pfam01576   76 ILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAarqklqlEKVTTEAKIKKLEEDILLLEDQNSKLSKERK 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  409 AKMDQLRAMVE--AADREKVELLNQLEEEKRKV-EDLQFRVEEESITKGDLERKRQISEdpenvatvsekSRIMELERDL 485
Cdd:pfam01576  156 LLEERISEFTSnlAEEEEKAKSLSKLKNKHEAMiSDLEERLKKEEKGRQELEKAKRKLE-----------GESTDLQEQI 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  486 ALRVKEVAELRGRLesSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTlsasNERMG 565
Cdd:pfam01576  225 AELQAQIAELRAQL--AKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQ----RRDLG 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  566 KENESLKTKLDHANKENSDVIELwKSKLESAIASHQQAMEELKVSFNKGVG----AQTAEFAELKTQMEKVKldyENEMS 641
Cdd:pfam01576  299 EELEALKTELEDTLDTTAAQQEL-RSKREQEVTELKKALEEETRSHEAQLQemrqKHTQALEELTEQLEQAK---RNKAN 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  642 NLKLKQ--ENEKSQHLKEIEALKAKLLEVTEEK---EQTLENLKAKLESVEDQHlVEMEDTLNKLQ-EAEIKVKELDVLQ 715
Cdd:pfam01576  375 LEKAKQalESENAELQAELRTLQQAKQDSEHKRkklEGQLQELQARLSESERQR-AELAEKLSKLQsELESVSSLLNEAE 453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  716 AKCNEQTKLIGSLTQQIRASEEKLldlaalqkansegkleiQKLSEQLQAAEKQIQNLETEKvggsskvSNLTKELQGKE 795
Cdd:pfam01576  454 GKNIKLSKDVSSLESQLQDTQELL-----------------QEETRQKLNLSTRLRQLEDER-------NSLQEQLEEEE 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  796 QKLLDLEKNLSAVNQVKDSLEKELqllkEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKL 875
Cdd:pfam01576  510 EAKRNVERQLSTLQAQLSDMKKKL----EEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDL 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  876 KEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTaQKAEQS 955
Cdd:pfam01576  586 LVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERT-NKQLRA 664

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  956 QQETLKTHQEELKK-----------MQDQLTDMKKQMETSQNQYK---DLQAKYEKETSEMITKHDADIKGFKQNlldAE 1021
Cdd:pfam01576  665 EMEDLVSSKDDVGKnvhelerskraLEQQVEEMKTQLEELEDELQateDAKLRLEVNMQALKAQFERDLQARDEQ---GE 741

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1022 EALKAAQKKNDELETQAEELKKQAEQA-----------KSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1090
Cdd:pfam01576  742 EKRRQLVKQVRELEAELEDERKQRAQAvaakkkleldlKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASR 821

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1091 ESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKI 1170
Cdd:pfam01576  822 DEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEE 901

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 2024460238 1171 TQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLL 1219
Cdd:pfam01576  902 QSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKEL 950
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 914-1146 8.24e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.16  E-value: 8.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  914 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQE------TLKTHQEELKKMQDQLTDMKKQMETSQNQ 987
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiaalarRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  988 YKDLQAKYEKETSEMITKHDADIKGF---KQNLLDAEEALKAAQKKNDELETQAEELKKQAEQakslssvLASARKEIEL 1064
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE-------LAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1065 MSDKMRDLISEKETLAQERNTLKLEKESLLSQhleMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQEST 1144
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ..
gi 2024460238 1145 EK 1146
Cdd:COG4942    249 AA 250
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1564-2085 8.66e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 8.66e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1564 IEILNRERTELQDKCQKlTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMrEKNKEFLTEKELLVQ 1643
Cdd:PRK03918   171 IKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1644 EKEKSETKLEEVIK--EKMI--LYKETEQLASKIEQLKS------DFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEK 1713
Cdd:PRK03918   249 SLEGSKRKLEEKIRelEERIeeLKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1714 EkmelVQENESLHAEWKSLVIINEEILKEKEKLsKEYYKLHEKVVALLEQTD---ADFSCR--------LLVSEGKHELL 1782
Cdd:PRK03918   329 R----IKELEEKEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELErlkKRLTGLtpeklekeLEELEKAKEEI 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1783 LEEMSNLALKLREIERLQAQ--TFMQKFEADKRA----------EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNE 1850
Cdd:PRK03918   404 EEEISKITARIGELKKEIKElkKAIEELKKAKGKcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELR 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1851 KLQNELdmlkqnnlKNEEELTKSKELL----NLENK-------KVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEEL 1919
Cdd:PRK03918   484 ELEKVL--------KKESELIKLKELAeqlkELEEKlkkynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1920 GRSRDEVTSHQKLEEERSVLNNQLLEMK-KSLPSNTLRESTLK---------KEIDEERASLQKSISDTSALITQKDEEL 1989
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneylelKDAEKELEREEKELKKLEEELDKAFEEL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1990 EKLRNEITVLRGENASAKTLQSV--VKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLlqdESAEDKQQE 2067
Cdd:PRK03918   636 AETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL---EEREKAKKE 712

                          570
                   ....*....|....*...
gi 2024460238 2068 IDFLNSVIVDLQRRNEEL 2085
Cdd:PRK03918   713 LEKLEKALERVEELREKV 730
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 337-825 8.91e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 8.91e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  337 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlEMEAKMDQLRA 416
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE-----------EAEEELEEAEA 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  417 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEEsitKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELR 496
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEA---LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  497 GRLESSKHIDDVDTSLS-LLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKL 575
Cdd:COG1196    436 EEEEEEEALEEAAEEEAeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  576 DHANKENS---DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAeLKTQMEKVKLDYENEMSNLKLKQENEKS 652
Cdd:COG1196    516 LAGLRGLAgavAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL-KAAKAGRATFLPLDKIRARAALAAALAR 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  653 QHLKEIEALKAKLLEVTEEKEQTLENlkAKLESVEDQHLVEMEDTLNKLQEAEIKVKELD----------VLQAKCNEQT 722
Cdd:COG1196    595 GAIGAAVDLVASDLREADARYYVLGD--TLLGRTLVAARLEAALRRAVTLAGRLREVTLEgeggsaggslTGGSRRELLA 672

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  723 KLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLE 802
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                          490       500
                   ....*....|....*....|...
gi 2024460238  803 KNLSAVNQVKDSLEKELQLLKEK 825
Cdd:COG1196    753 LEELPEPPDLEELERELERLERE 775
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
952-1197 9.23e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 60.80  E-value: 9.23e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  952 AEQSQQETLKTHQEELKK----MQDQLTDMKKQMETSQNQYKDLQAKYeketsemitkhdadikgfkqNLLDAEEALKAA 1027
Cdd:COG3206    158 AEAYLEQNLELRREEARKalefLEEQLPELRKELEEAEAALEEFRQKN--------------------GLVDLSEEAKLL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1028 QKKNDELETQAEELKKQAEQAKSLssvLASARKEIELMSDKMRDLISEKE--TLAQERNTLKLEKESLLSQHLEMESKIL 1105
Cdd:COG3206    218 LQQLSELESQLAEARAELAEAEAR---LAALRAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELSARYTPNHPDVI 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1106 LVQQDREELwtkNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL 1185
Cdd:COG3206    295 ALRAQIAAL---RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL 371

                          250
                   ....*....|..
gi 2024460238 1186 QQLKELQANKDA 1197
Cdd:COG3206    372 QRLEEARLAEAL 383
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1332-1973 9.45e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 9.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1332 ETEReKLEKmTKDNMD--------LKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRL-LAEREELVNENKAV 1402
Cdd:COG1196    176 EAER-KLEA-TEENLErledilgeLERQLEPLE---------RQAEKAERYRELKEELKELEAELlLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1403 TEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQEl 1482
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE- 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1483 dfsAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSS 1562
Cdd:COG1196    324 ---ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1563 DIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLV 1642
Cdd:COG1196    401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1643 QEKEKSETKLEEvikekmilyKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQEN 1722
Cdd:COG1196    481 ELLEELAEAAAR---------LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1723 eslhaewkslVIINEEILKEKEKLSKEYyKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQ 1802
Cdd:COG1196    552 ----------VVEDDEVAAAAIEYLKAA-KAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1803 TFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELdmlkqnnLKNEEELTKSKELLNLENK 1882
Cdd:COG1196    621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL-------LEAEAELEELAERLAEEEL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1883 KVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtsHQKLEEERSVLNNQLLEMKKSLPSntlrESTLKK 1962
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL--LEELLEEEELLEEEALEELPEPPD----LEELER 767

                          650
                   ....*....|.
gi 2024460238 1963 EIDEERASLQK 1973
Cdd:COG1196    768 ELERLEREIEA 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 805-1059 1.05e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.78  E-value: 1.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  805 LSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQ 884
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  885 LTEAKVKLENDIAEImkssgdssaqlmkmndeLRLKERQLEQIQLELTKANEKAVQLQKNVE--QTAQKAEQSQQETLKT 962
Cdd:COG4942     95 LRAELEAQKEELAEL-----------------LRALYRLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  963 HQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1042
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAE----RQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233

                          250
                   ....*....|....*..
gi 2024460238 1043 KQAEQAKSLSSVLASAR 1059
Cdd:COG4942    234 AEAAAAAERTPAAGFAA 250
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 540-1191 1.10e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.75  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  540 KEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSKLESAIASHQQAMEELKVSfnkgvgAQT 619
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARI--EELRAQEAVLEETQERINRA------RKA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  620 AEFAELKTQMEKVKLDYENEMSNLKlKQENEKSQHLKEIEALKAKLLEVtEEKEQTLENLKAKLESVEDQHLV------- 692
Cdd:TIGR00618  293 APLAAHIKAVTQIEQQAQRIHTELQ-SKMRSRAKLLMKRAAHVKQQSSI-EEQRRLLQTLHSQEIHIRDAHEVatsirei 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  693 ---EMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQ 769
Cdd:TIGR00618  371 scqQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCT 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  770 IQNLETEK---VGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFT------SAVDGAENAQRAM 840
Cdd:TIGR00618  451 AQCEKLEKihlQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIhpnparQDIDNPGPLTRRM 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  841 QETINKLNQKEEQFALMSSELEQLKSNLTvmetKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND-ELRL 919
Cdd:TIGR00618  531 QRGEQTYAQLETSEEDVYHQLTSERKQRA----SLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEkLSEA 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  920 KERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDL-QAKYEKE 998
Cdd:TIGR00618  607 EDMLACEQHALLRKLQPEQDLQDVRLHL-QQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASrQLALQKM 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  999 TSEmitkhdadikgfKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQaksLSSVLASARKEIELMSDKMRDLISEKE- 1077
Cdd:TIGR00618  686 QSE------------KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNE---IENASSSLGSDLAAREDALNQSLKELMh 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1078 ---------TLAQERNTLKLEKESLLSQHL-----EMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQES 1143
Cdd:TIGR00618  751 qartvlkarTEAHFNNNEEVTAALQTGAELshlaaEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEE 830

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 2024460238 1144 TEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1191
Cdd:TIGR00618  831 EQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
785-1348 1.27e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  785 SNLTKELQGKEQKllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQramqETINKLNQKEEQFALMSSELEQL 864
Cdd:PRK02224   190 DQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEAD----EVLEEHEERREELETLEAEIEDL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  865 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKN 944
Cdd:PRK02224   264 RETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  945 VEQTAQKAEQSQQETlKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEkETSEMITKHDADIKGFKQNLLDAEEAL 1024
Cdd:PRK02224   344 AESLREDADDLEERA-EELREEAAELESELEEAREAVEDRREEIEELEEEIE-ELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1025 KAAQKKNDELETQAEELKKQAEQAKSL----------SSVLASARKE-IELMSDKMRDLISEKETLAQERNTLKlEKESL 1093
Cdd:PRK02224   422 DELREREAELEATLRTARERVEEAEALleagkcpecgQPVEGSPHVEtIEEDRERVEELEAELEDLEEEVEEVE-ERLER 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1094 LSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQE 1173
Cdd:PRK02224   501 AEDLVEAEDRIERLEERREDL----EELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1174 NDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD----LARNQRE 1249
Cdd:PRK02224   577 LNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEarieEAREDKE 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1250 LLQE-VSILTAERDSAQEKDLDLKSTHIALKNEIDCLlqtnRSLQSEKEMLLKSREELcVSLANTANENQAL--KLRKDE 1326
Cdd:PRK02224   657 RAEEyLEQVEEKLDELREERDDLQAEIGAVENELEEL----EELRERREALENRVEAL-EALYDEAEELESMygDLRAEL 731

                          570       580
                   ....*....|....*....|..
gi 2024460238 1327 MQTELETerekLEKMTKDNMDL 1348
Cdd:PRK02224   732 RQRNVET----LERMLNETFDL 749
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1789-2067 1.36e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1789 LALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEE 1868
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1869 ELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKK 1948
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL---EEAEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1949 SLPSNTLRESTLKKEIDE---ERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEE 2025
Cdd:COG1196    373 ELAEAEEELEELAEELLEalrAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024460238 2026 KVKNLEQKLKAKSEQPLTVTsPSGDIAANLLQDESAEDKQQE 2067
Cdd:COG1196    453 ELEEEEEALLELLAELLEEA-ALLEAALAELLEELAEAAARL 493
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 480-1195 1.52e-08

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 60.22  E-value: 1.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  480 ELERDLALRVKEVAELRGRLESSKHIDDVDTSLSL----LQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIK 555
Cdd:pfam10174   40 ELKKERALRKEEAARISVLKEQYRVTQEENQHLQLtiqaLQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFR 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  556 TLSASNERMGKENESLKTKLDHANKEnsdvIELWKSKLESAIASHQQAMEELK--------VSFNKGVGAQTAEfAELKT 627
Cdd:pfam10174  120 RLQSEHERQAKELFLLRKTLEEMELR----IETQKQTLGARDESIKKLLEMLQskglpkksGEEDWERTRRIAE-AEMQL 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  628 QMEKVKLDyENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIK 707
Cdd:pfam10174  195 GHLEVLLD-QKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEE 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  708 VKELDVLQAKCNEQTKLIGSLTQQIRASEEKLL----DLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggssk 783
Cdd:pfam10174  274 IKQMEVYKSHSKFMKNKIDQLKQELSKKESELLalqtKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTE------- 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  784 VSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ 863
Cdd:pfam10174  347 VDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKS 426

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  864 LKSN-------LTVMETKLKEREE-----REQQLTEAKVKLEnDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLEL 931
Cdd:pfam10174  427 LQTDssntdtaLTTLEEALSEKERiierlKEQREREDRERLE-ELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHA 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  932 T-------KANEKAVQLQKNVEQTAQKAEQSQQETLKTHQ-EELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM- 1002
Cdd:pfam10174  506 SslassglKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNaEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLl 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1003 -ITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSsVLASARKEIELMSDKMRDLISEKETLAQ 1081
Cdd:pfam10174  586 gILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQ-LLEEARRREDNLADNSQQLQLEELMGAL 664

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1082 ERNTLKLEkesllsqhlEMESKILLVQQDREELWTKNEELNSENKKILKqkEAAEAKsrQESTekVALISEKSKLLSEIE 1161
Cdd:pfam10174  665 EKTRQELD---------ATKARLSSTQQSLAEKDGHLTNLRAERRKQLE--EILEMK--QEAL--LAAISEKDANIALLE 729

                          730       740       750
                   ....*....|....*....|....*....|....
gi 2024460238 1162 TAQADLLKITQENDALRSSESTLLQQLKELQANK 1195
Cdd:pfam10174  730 LSSSKKKKTQEEVMALKREKDRLVHQLKQQTQNR 763
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1093-1936 2.05e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 2.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1093 LLSQHLEMESKILLVQQDREElwtkNEELNSENKKILKQKEAAEAKS----RQESTEKVALISEKSKLLSEIETAQADLL 1168
Cdd:pfam02463  125 LESQGISPEAYNFLVQGGKIE----IIAMMKPERRLEIEEEAAGSRLkrkkKEALKKLIEETENLAELIIDLEELKLQEL 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1169 KIT-QENDALRSSESTLLQQLKELQANKDAVDVACQKHIKE-REELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARN 1246
Cdd:pfam02463  201 KLKeQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1247 QRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDE 1326
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1327 MQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKS--SREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTE 1404
Cdd:pfam02463  361 LEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElkSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIE 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1405 KLTKATADAVLAETAFTEKINELNLEKESVF------SKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR 1478
Cdd:pfam02463  441 LKQGKLTEEKEELEKQELKLLKDELELKKSEdllketQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1479 EQELDFSAKRLLVQENTTLKYS---IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSS 1555
Cdd:pfam02463  521 GGRIISAHGRLGDLGVAVENYKvaiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEID 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1556 SFNTCSSDIEILNRERTELQDKCQKlTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKNKEFL 1635
Cdd:pfam02463  601 PILNLAQLDKATLEADEDDKRAKVV-EGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1636 TEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK 1715
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1716 MELVQ------------ENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRL--LVSEGKHEL 1781
Cdd:pfam02463  760 EEKEEekselslkekelAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkiKEEELEELA 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1782 LLEEMSNLALKLREIErlqaqTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQ 1861
Cdd:pfam02463  840 LELKEEQKLEKLAEEE-----LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEE 914

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238 1862 NNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEER 1936
Cdd:pfam02463  915 KENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEER 989
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 406-1408 2.26e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.80  E-value: 2.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  406 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRqisedpenvatVSEKSRIMELERDL 485
Cdd:pfam01576   72 ELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEK-----------VTTEAKIKKLEEDI 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  486 ALrvkeVAELRGRLESSKhiddvdtslSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESS----EEALRKEiktlsasn 561
Cdd:pfam01576  141 LL----LEDQNSKLSKER---------KLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMisdlEERLKKE-------- 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  562 ERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFA------ELKTQMEKVKLD 635
Cdd:pfam01576  200 EKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNalkkirELEAQISELQED 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  636 YENEMSnLKLKQENEKSQHLKEIEALKAKLL----------EVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAe 705
Cdd:pfam01576  280 LESERA-ARNKAEKQRRDLGEELEALKTELEdtldttaaqqELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQA- 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  706 ikvkeLDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAA----LQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 781
Cdd:pfam01576  358 -----LEELTEQLEQAKRNKANLEKAKQALESENAELQAelrtLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELA 432

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  782 SKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTsavdgaenaqramQETINKLNqkeeqfalMSSEL 861
Cdd:pfam01576  433 EKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQ-------------EETRQKLN--------LSTRL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  862 EQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQL 941
Cdd:pfam01576  492 RQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKL 571

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  942 QKNVEQTAQKAEQS--QQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDAdikgFKQNLLD 1019
Cdd:pfam01576  572 EKTKNRLQQELDDLlvDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALS----LARALEE 647

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1020 AEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEkesllsqhLE 1099
Cdd:pfam01576  648 ALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLR--------LE 719

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1100 MESKILLVQQDReELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLlkitqenDALRS 1179
Cdd:pfam01576  720 VNMQALKAQFER-DLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQI-------DAANK 791

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1180 SESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKlleENDRVIKDKDDVIQRLQssyDDLARNQRELLQevsiLTA 1259
Cdd:pfam01576  792 GREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSK---ESEKKLKNLEAELLQLQ---EDLAASERARRQ----AQQ 861

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1260 ERDSAQEKDLDLKSTHIALKNEidcllqtNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLE 1339
Cdd:pfam01576  862 ERDELADEIASGASGKSALQDE-------KRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQ 934

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460238 1340 KMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTK 1408
Cdd:pfam01576  935 KSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKK 1003
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1316-1894 4.75e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 4.75e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1316 ENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNsEKIHLLQEAlfasEQRLLAEREEL 1395
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-LELEEAQAE----EYELLAELARL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1396 VNENKAVTEKLTkatadavlaetAFTEKINELNLEKEsvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSD 1475
Cdd:COG1196    301 EQDIARLEERRR-----------ELEERLEELEEELA-------ELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1476 MKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSS 1555
Cdd:COG1196    363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1556 SFNTCSSDIEILNRERTELQDKcQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKNKEFL 1635
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLEL-LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1636 TEKEL--LVQEKEKSETKLEEVIKEKM--ILYKETEQLASKIEQLKSD------FTSLSVSKAE--LEDVHSCVSVMLDE 1703
Cdd:COG1196    522 LAGAVavLIGVEAAYEAALEAALAAALqnIVVEDDEVAAAAIEYLKAAkagratFLPLDKIRARaaLAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1704 LQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKlskeyyklHEKVVALLEQTDADFScRLLVSEGKHELLL 1783
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLA--------GRLREVTLEGEGGSAG-GSLTGGSRRELLA 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1784 EEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNN 1863
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                          570       580       590
                   ....*....|....*....|....*....|.
gi 2024460238 1864 LKNEEELTKSKELlnleNKKVEELKKEFEAL 1894
Cdd:COG1196    753 LEELPEPPDLEEL----ERELERLEREIEAL 779
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
838-1259 5.26e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  838 RAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndIAEIMKSSGDSSAQLMKMNDEL 917
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP--LYQELEALEAELAELPERLEEL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  918 RLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEK 997
Cdd:COG4717    152 EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  998 ETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVL--------ASARKEIELMSDKM 1069
Cdd:COG4717    232 LENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLflllarekASLGKEAEELQALP 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1070 RDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK--EAAEAKSRQESTEKV 1147
Cdd:COG4717    312 ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllAEAGVEDEEELRAAL 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1148 ALISEKSKLLSEIETAQADLLKITQENDALRS--SESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRv 1225
Cdd:COG4717    392 EQAEEYQELKEELEELEEQLEELLGELEELLEalDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE- 470

                          410       420       430
                   ....*....|....*....|....*....|....
gi 2024460238 1226 ikdkddvIQRLQSSYDDLARNQRELLQEVSILTA 1259
Cdd:COG4717    471 -------LAELLQELEELKAELRELAEEWAALKL 497
PTZ00121 PTZ00121
MAEBL; Provisional
 1359-2032 6.39e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 6.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1359 LEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAfTEKINELNLEKESVFSKS 1438
Cdd:PTZ00121  1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKA 1292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1439 LQFEKHNEAL----LREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLE 1514
Cdd:PTZ00121  1293 DEAKKAEEKKkadeAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK 1372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1515 NQEliaCRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTV 1594
Cdd:PTZ00121  1373 KEE---AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1595 EKKARVLDKESFLLERMELQNNIGFLEKEVEEMRE-----KNKEFLTEKELLVQEKEKSETKLEEVIKEKMilYKETEQL 1669
Cdd:PTZ00121  1450 KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKadeakKKAEEAKKKADEAKKAAEAKKKADEAKKAEE--AKKADEA 1527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1670 ASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK----MELVQENESLHAEWKSLVIINEEILKEKEK 1745
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEedknMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1746 LSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVT 1825
Cdd:PTZ00121  1608 KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1826 KEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQL 1905
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1906 AALQEENVKLAEELGRSRDEVTSHQKLEEERSVlnNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQK 1985
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKI--KDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2024460238 1986 DEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQ 2032
Cdd:PTZ00121  1846 ADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEK 1892
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 800-2032 6.45e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 58.52  E-value: 6.45e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  800 DLEKNLSAVNQVKdsleKELQLLKEkFTSAVDGAENAQRAMQETINKLNQKEEQF--ALMSSELEQ-LKSNLTVM----E 872
Cdd:TIGR01612  484 DIDENSKQDNTVK----LILMRMKD-FKDIIDFMELYKPDEVPSKNIIGFDIDQNikAKLYKEIEAgLKESYELAknwkK 558

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  873 TKLKEREEREQQlTEAKVKLENDIAEIMKssgdssaQLMKMNDEL----RLKERQLEQIQlELTKANE---KAVQLQKNV 945
Cdd:TIGR01612  559 LIHEIKKELEEE-NEDSIHLEKEIKDLFD-------KYLEIDDEIiyinKLKLELKEKIK-NISDKNEyikKAIDLKKII 629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  946 EQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKqmETSQNQYKDLQAKYeKETSEMITKHDADIKGFKQNLLDAEEALK 1025
Cdd:TIGR01612  630 ENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKS--ELSKIYEDDIDALY-NELSSIVKENAIDNTEDKAKLDDLKSKID 706

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1026 AAQKKNDELETQAEELkkqaeqakSLSSvlasarkeIELMSDKMRDLISE--KETLAQERNTLKLEKESLLSQHLEMESK 1103
Cdd:TIGR01612  707 KEYDKIQNMETATVEL--------HLSN--------IENKKNELLDIIVEikKHIHGEINKDLNKILEDFKNKEKELSNK 770

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1104 IllvqqdrEELWTKNEELNSENKKILKQKEAAEAKSRQEST--EKVALISEKSK-LLSEIETAQADLLKITQEndalrss 1180
Cdd:TIGR01612  771 I-------NDYAKEKDELNKYKSKISEIKNHYNDQINIDNIkdEDAKQNYDKSKeYIKTISIKEDEIFKIINE------- 836

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1181 estlLQQLKELQANKDAVDVACQKHIKEREELEHYQKlleeNDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSiltae 1260
Cdd:TIGR01612  837 ----MKFMKDDFLNKVDKFINFENNCKEKIDSEHEQF----AELTNKIKAEISDDKLNDYEKKFNDSKSLINEIN----- 903

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1261 rdSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEK 1340
Cdd:TIGR01612  904 --KSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDK 981

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1341 MTKDnmdlkASLSSLsnfleemkssrEASNSEKIHL---LQEALFASEQRLL----AEREELVNEnkaVTEKLTKATADA 1413
Cdd:TIGR01612  982 AFKD-----ASLNDY-----------EAKNNELIKYfndLKANLGKNKENMLyhqfDEKEKATND---IEQKIEDANKNI 1042

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1414 VLAETAFTEKINELNLEKESVFSKSLqfEKHNEALLREKDELERKYSELlDEKKSLENaFSDMKREQELDFS-----AKR 1488
Cdd:TIGR01612 1043 PNIEIAIHTSIYNIIDEIEKEIGKNI--ELLNKEILEEAEINITNFNEI-KEKLKHYN-FDDFGKEENIKYAdeinkIKD 1118

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1489 LLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEA------QDARRTLENELAAVSHAKQVLSSsFNTCSS 1562
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKAisnddpEEIEKKIENIVTKIDKKKNIYDE-IKKLLN 1197

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1563 DIEILNRERTELQdkcqkltgEVENMkeNLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMRE-KNKEFLTEKELL 1641
Cdd:TIGR01612 1198 EIAEIEKDKTSLE--------EVKGI--NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEiKEKSPEIENEMG 1267

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1642 VQEKEKSETKLEEV----IKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDV--------------HSCVSVMLDE 1703
Cdd:TIGR01612 1268 IEMDIKAEMETFNIshddDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDIkkelqknlldaqkhNSDINLYLNE 1347

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1704 LQHKYEVTEKEKM--------ELVQENESLHAEWKSLVIINEEILKE-KEKLSKEYYKlhEKVVALLEQTDADfSCRLLV 1774
Cdd:TIGR01612 1348 IANIYNILKLNKIkkiidevkEYTKEIEENNKNIKDELDKSEKLIKKiKDDINLEECK--SKIESTLDDKDID-ECIKKI 1424

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1775 SEGKHELLLEEMSNLAL--KLREIERLQAQTFMQKFEADKRAEEVLQTmekvtkEKDAIHQEKIETLASLENSRQTNEKL 1852
Cdd:TIGR01612 1425 KELKNHILSEESNIDTYfkNADENNENVLLLFKNIEMADNKSQHILKI------KKDNATNDHDFNINELKEHIDKSKGC 1498

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1853 QNELDmlkqnnlKNEEELTKSKELLNLENKKVEELKKEFEALKL------AAAQKSQQLAALQEENVKLAEELGRSRDEV 1926
Cdd:TIGR01612 1499 KDEAD-------KNAKAIEKNKELFEQYKKDVTELLNKYSALAIknkfakTKKDSEIIIKEIKDAHKKFILEAEKSEQKI 1571

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1927 TS--HQKLEEERSVLNNQ-----LLEMKKSL---PSNTLRESTLKKEIDE---ERASLQKSISDTSalITQKDEELEKLR 1993
Cdd:TIGR01612 1572 KEikKEKFRIEDDAAKNDksnkaAIDIQLSLenfENKFLKISDIKKKINDclkETESIEKKISSFS--IDSQDTELKENG 1649

                         1290      1300      1310
                   ....*....|....*....|....*....|....*....
gi 2024460238 1994 NEITvlrgenasakTLQSVVKTLESDKLKLEEKVKNLEQ 2032
Cdd:TIGR01612 1650 DNLN----------SLQEFLESLKDQKKNIEDKKKELDE 1678
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 667-1585 7.36e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 57.88  E-value: 7.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  667 EVTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKVKE-LDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAA- 744
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESE-LKELEKKHQQLCEEKNALQEqLQAETELCAEAEEMRARLAARKQELEEILHELESr 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  745 ----------LQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLtkelqgkEQKLLDLEKNLSAVNQVKDS 814
Cdd:pfam01576   84 leeeeersqqLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKL-------EEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  815 LEKELQLLKEKFTSAVDGAENaqramqetINKLNQKEEqfalmsseleqlkSNLTVMETKLKEREEREQQLTEAKVKLEN 894
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKS--------LSKLKNKHE-------------AMISDLEERLKKEEKGRQELEKAKRKLEG 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  895 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNV-EQTAQKAEqsQQETLKTHQEELKKMQDQ 973
Cdd:pfam01576  216 ESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIrELEAQISE--LQEDLESERAARNKAEKQ 293

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  974 LTDMKKQMETSQNQYKDLQAKYEKEtSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQA-EELKKQAEQAKSLS 1052
Cdd:pfam01576  294 RRDLGEELEALKTELEDTLDTTAAQ-QELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKRNK 372

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1053 SVLASARKEIElmsDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSE-------- 1124
Cdd:pfam01576  373 ANLEKAKQALE---SENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSElesvssll 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1125 ----NKKILKQKEAAEAKSR---------QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL--- 1188
Cdd:pfam01576  450 neaeGKNIKLSKDVSSLESQlqdtqellqEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLsdm 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1189 -KELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSIL---------- 1257
Cdd:pfam01576  530 kKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLekkqkkfdqm 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1258 -----------TAERDSAQEKDLDLKSTHIALKNEIDCLL-------QTNRSLQSEKEMLLKSREELCVSLANTANENQA 1319
Cdd:pfam01576  610 laeekaisaryAEERDRAEAEAREKETRALSLARALEEALeakeeleRTNKQLRAEMEDLVSSKDDVGKNVHELERSKRA 689

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1320 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAER------- 1392
Cdd:pfam01576  690 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERkqraqav 769

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1393 ------EELVNENKAVTEKLTKATADAV----LAETAFTEKINELN---LEKESVFSKSLQFEKHNEALLREKDELERKY 1459
Cdd:pfam01576  770 aakkklELDLKELEAQIDAANKGREEAVkqlkKLQAQMKDLQRELEearASRDEILAQSKESEKKLKNLEAELLQLQEDL 849

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1460 SELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLeNQELiacrsdLSDLLKEAQDARRTL 1539
Cdd:pfam01576  850 AASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQS-NTEL------LNDRLRKSTLQVEQL 922

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|....*.
gi 2024460238 1540 ENELAAVSHAKQVLSSSFNTcssdieiLNRERTELQDKCQKLTGEV 1585
Cdd:pfam01576  923 TTELAAERSTSQKSESARQQ-------LERQNKELKAKLQEMEGTV 961
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2160-2176 7.75e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.75e-08
                           10
                   ....*....|....*..
gi 2024460238 2160 RPYCDTCEMFGHWTADC 2176
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 915-1113 1.55e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 55.99  E-value: 1.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  915 DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDlQAK 994
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-LEALQAEIDKLQAEIAEAEAEIEERREELGE-RAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  995 YEKETSEMITKHDA-----DIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKM 1069
Cdd:COG3883     94 ALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2024460238 1070 RDLISEKE----TLAQERNTLKLEKESLLSQHLEMESKILLVQQDREE 1113
Cdd:COG3883    174 EAQQAEQEallaQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1442-1996 1.62e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1442 EKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQeldfsakRLLVQENTTLKYSIEALEEELKKKNLENQELIAC 1521
Cdd:COG1196    224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAEL-------AELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1522 RSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKAR-- 1599
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELae 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1600 -VLDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKS 1678
Cdd:COG1196    377 aEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1679 DFTSLSVSKAELEDVHSCVSVMLDELQHKYEvtEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLH--EK 1756
Cdd:COG1196    457 EEEALLELLAELLEEAALLEAALAELLEELA--EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgvEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1757 VVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKI 1836
Cdd:COG1196    535 AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1837 ETL--ASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1914
Cdd:COG1196    615 YYVlgDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1915 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRN 1994
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774


                   ..
gi 2024460238 1995 EI 1996
Cdd:COG1196    775 EI 776
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 354-1096 2.23e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.52  E-value: 2.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  354 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALV---RDGHDRHVLEMEAKMDQLRAMVEAADREKVELLN 430
Cdd:pfam02463  242 LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQeeeLKLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  431 QLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKE-----------VAELRGRL 499
Cdd:pfam02463  322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLEserlssaaklkEEELELKS 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  500 ESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHAN 579
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  580 KENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVG---------AQTAEFAELKTQMEKVKLDYENEMSNLKLKQENE 650
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisaHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  651 KSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVE--------DQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQT 722
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidpilnlaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  723 KLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLE 802
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  803 KNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ--LKSNLTVMETKLKEREE 880
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKteKLKVEEEKEEKLKAQEE 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  881 REqqltEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNV----EQTAQKAEQSQ 956
Cdd:pfam02463  802 EL----RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEitkeELLQELLLKEE 877

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  957 QETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELET 1036
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEE 957

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1037 QAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQ 1096
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
636-1099 3.55e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.54  E-value: 3.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  636 YENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTE------EKEQTLENLKAKLESVEDQ--HLVEMEDTLNKLQEAEIK 707
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEkeeeyaELQEELEELEEELEELEAEleELREELEKLEKLLQLLPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  708 VKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQL-QAAEKQIQNLETEKVGGSSKVSN 786
Cdd:COG4717    131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAE 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  787 LTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKS 866
Cdd:COG4717    211 LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLF 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  867 NLTVMETKLKEREEREQQLTEAKVKLEN-DIAEIMKSSGDSSAQLmkmNDELRLKERQLEQIQLELTKANEKAVQLQknv 945
Cdd:COG4717    291 LLLAREKASLGKEAEELQALPALEELEEeELEELLAALGLPPDLS---PEELLELLDRIEELQELLREAEELEEELQ--- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  946 eqtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDA-DIKGFKQNLLDAEEAL 1024
Cdd:COG4717    365 ---LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAlDEEELEEELEELEEEL 441

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238 1025 KAAQKKNDELETQAEELKKQAEQAKSlSSVLASARKEIElmsdkmrDLISEKETLAQERNTLKLEKEsLLSQHLE 1099
Cdd:COG4717    442 EELEEELEELREELAELEAELEQLEE-DGELAELLQELE-------ELKAELRELAEEWAALKLALE-LLEEARE 507
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 949-1193 3.64e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  949 AQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemITKHDADIKGFKQNLLDAEEALKAAQ 1028
Cdd:COG4942     19 ADAAAEAEAE-LEQLQQEIAELEKELAALKKEEKALLKQLAALERR--------IAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1029 KKNDELETQAEELKKQ-AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLlsqhlemeskillv 1107
Cdd:COG4942     90 KEIAELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL-------------- 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1108 QQDREELWTKNEELNSEnkkiLKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQAdllKITQENDALRSSESTLLQQ 1187
Cdd:COG4942    156 RADLAELAALRAELEAE----RAELEALLAELEEERAALEALKAERQKLLARLEKELA---ELAAELAELQQEAEELEAL 228


                   ....*.
gi 2024460238 1188 LKELQA 1193
Cdd:COG4942    229 IARLEA 234
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1799-2113 3.66e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.85  E-value: 3.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1799 LQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqeKIETLASLENSRQ-------TNEKLQNELDMLKQNNLKNEEELT 1871
Cdd:COG5022    765 LQALKRIKKIQVIQHGFRLRRLVDYELKWRLFI---KLQPLLSLLGSRKeyrsylaCIIKLQKTIKREKKLRETEEVEFS 841

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1872 KSKELLNLENKKVEELKKEFEALKlaaaqKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLP 1951
Cdd:COG5022    842 LKAEVLIQKFGRSLKAKKRFSLLK-----KETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLS 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1952 SNTLRESTLKKEID--EERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKN 2029
Cdd:COG5022    917 SDLIENLEFKTELIarLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKN 996

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 2030 LEQKLKAKSEQPLTVTSPSGDiaANLLQDESAEdKQQEIDFLNSVIVDLQRRNEELNLKiqRMCEAALNGNEEETINYDS 2109
Cdd:COG5022    997 FKKELAELSKQYGALQESTKQ--LKELPVEVAE-LQSASKIISSESTELSILKPLQKLK--GLLLLENNQLQARYKALKL 1071


                   ....
gi 2024460238 2110 EEEG 2113
Cdd:COG5022   1072 RREN 1075
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 567-1353 3.78e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 55.50  E-value: 3.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  567 ENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKvsfnKGVGAQTAEFAELKTQMEKVKLDYENEMS-NLKL 645
Cdd:pfam05483   71 ENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENR----KIIEAQRKAIQELQFENEKVSLKLEEEIQeNKDL 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  646 KQENEKSQH----LKEIEALKAKLLEVTE-EKEQT----------LENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKE 710
Cdd:pfam05483  147 IKENNATRHlcnlLKETCARSAEKTKKYEyEREETrqvymdlnnnIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQH 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  711 LDV-LQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKansEGKLEIQKLSEQLQAAEKQIQNLETEKvggsskvSNLTK 789
Cdd:pfam05483  227 LEEeYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLE---ESRDKANQLEEKTKLQDENLKELIEKK-------DHLTK 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  790 ELQgkeqkllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENaqramqeTINKLNQKEEQFALMSSELEQLKSNLT 869
Cdd:pfam05483  297 ELE-------DIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEA-------QMEELNKAKAAHSFVVTEFEATTCSLE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  870 -VMETKLKEREEREQQLTEAKVKLENdiaeimkssgdSSAQLMKMNDELRLKERQLEQIQLELTKaNEKAVQLQKNVEQT 948
Cdd:pfam05483  363 eLLRTEQQRLEKNEDQLKIITMELQK-----------KSSELEEMTKFKNNKEVELEELKKILAE-DEKLLDEKKQFEKI 430

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  949 AQKAEQSQQET---LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsemitkhdadikgfkqnlldaeealk 1025
Cdd:pfam05483  431 AEELKGKEQELiflLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKE--------------------------- 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1026 aaQKKNDELETQAEEL----KKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLlsqhleme 1101
Cdd:pfam05483  484 --KLKNIELTAHCDKLllenKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESV-------- 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1102 skillvqqdREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSE 1181
Cdd:pfam05483  554 ---------REEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKG 624

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1182 STLLQQLK--ELQANKDAVDVACQKHiKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTA 1259
Cdd:pfam05483  625 SAENKQLNayEIKVNKLELELASAKQ-KFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIA 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1260 ERDSAQEKDldlKSTHIALKNEIDCLLQTNRSLQSEKEMLlksREELCVSLANTANENQALKlrkdemqTELETEREKLE 1339
Cdd:pfam05483  704 EMVALMEKH---KHQYDKIIEERDSELGLYKNKEQEQSSA---KAALEIELSNIKAELLSLK-------KQLEIEKEEKE 770

                          810
                   ....*....|....
gi 2024460238 1340 KMTKDNMDLKASLS 1353
Cdd:pfam05483  771 KLKMEAKENTAILK 784
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 845-1482 3.94e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 3.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  845 NKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQL 924
Cdd:TIGR04523   33 TEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  925 EQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQeELKKMQDQLTDMKKQMEtsqnQYKDLQAKYEKETSEmIT 1004
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEK-ELEKLNNKYNDLKKQKE----ELENELNLLEKEKLN-IQ 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1005 KHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKslssvlasarKEIELMSDKMRDLISEKETLAQERN 1084
Cdd:TIGR04523  187 KNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLK----------DNIEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1085 TLKLEKESLLSQhleMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKvalISEKSKLLSEIETaq 1164
Cdd:TIGR04523  257 QLKDEQNKIKKQ---LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSE---LKNQEKKLEEIQN-- 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1165 adllKITQENDALRSSESTlLQQLKELQANKDAVDVACQKHIKERE-ELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDL 1243
Cdd:TIGR04523  329 ----QISQNNKIISQLNEQ-ISQLKKELTNSESENSEKQRELEEKQnEIEKLKKENQSYKQEIKNLESQINDLESKIQNQ 403

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1244 ARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLR 1323
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1324 KDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEK------IHLLQEALFASEQRLLAER-EELV 1396
Cdd:TIGR04523  484 LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekeskISDLEDELNKDDFELKKENlEKEI 563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1397 NENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDM 1476
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643


                   ....*.
gi 2024460238 1477 KREQEL 1482
Cdd:TIGR04523  644 KQEVKQ 649
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
644-1063 5.29e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.77  E-value: 5.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  644 KLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDVLQAKCNEQTK 723
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL-----EKLEKLLQLLPLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  724 LIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQL-QAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLE 802
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  803 KNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREERE 882
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  883 QQLTEAKVKLEN-DIAEIMKSSG--------------DSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ 947
Cdd:COG4717    307 LQALPALEELEEeELEELLAALGlppdlspeellellDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  948 TAQKAEQSQQetLKTHQEELKKMQDQLTDMKKQMET--SQNQYKDLQAKYE------KETSEMITKHDADIKGFKQNLLD 1019
Cdd:COG4717    387 LRAALEQAEE--YQELKEELEELEEQLEELLGELEEllEALDEEELEEELEeleeelEELEEELEELREELAELEAELEQ 464

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 2024460238 1020 AEEALKAAQKKnDELETQAEELKKQAEQAKSL---SSVLASARKEIE 1063
Cdd:COG4717    465 LEEDGELAELL-QELEELKAELRELAEEWAALklaLELLEEAREEYR 510
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1501-2051 6.84e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 6.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1501 IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLsssfNTCSSDIEILNRERTELQDKCQK 1580
Cdd:TIGR04523  147 IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKL----ELLLSNLKKKIQKNKSLESQISE 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1581 LTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQekekSETKLEEVIKEKM 1660
Cdd:TIGR04523  223 LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE----LEKQLNQLKSEIS 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1661 ILYKETEQLASKieQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEIL 1740
Cdd:TIGR04523  299 DLNNQKEQDWNK--ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLK 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1741 KEKEKLSKEYYKLHEKVVALLEQtdadFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEE--VL 1818
Cdd:TIGR04523  377 KENQSYKQEIKNLESQINDLESK----IQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQdsVK 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1819 QTMEKVTKEKDAIHQEKIETL-ASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLA 1897
Cdd:TIGR04523  453 ELIIKNLDNTRESLETQLKVLsRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESE 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1898 AAQKSQQLAALQEENVKLAEELGRSrdevtshqKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEerasLQKSISD 1977
Cdd:TIGR04523  533 KKEKESKISDLEDELNKDDFELKKE--------NLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ----KEKEKKD 600

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024460238 1978 TSALITQKDEELEKLRNEITVLRGENasaktlqsvvKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDI 2051
Cdd:TIGR04523  601 LIKEIEEKEKKISSLEKELEKAKKEN----------EKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEI 664
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 587-1047 6.85e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 54.96  E-value: 6.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  587 ELWKSKleSAIASHQQAMEELkvsfnkgvgaqTAEFAELKTQMEKVKLDYENEMSNLKLKQE----NEKSQHLKE-IEAL 661
Cdd:COG3096    293 ELFGAR--RQLAEEQYRLVEM-----------ARELEELSARESDLEQDYQAASDHLNLVQTalrqQEKIERYQEdLEEL 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  662 KAKLlevtEEKEQTLENLKAKLESVEDQhlvemedtlnkLQEAEIKVKEL-----DVLQAKCNEQTKLIgSLTQQIRASE 736
Cdd:COG3096    360 TERL----EEQEEVVEEAAEQLAEAEAR-----------LEAAEEEVDSLksqlaDYQQALDVQQTRAI-QYQQAVQALE 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  737 E--KLLDLAALQKANSEGKLEiqklseQLQAAEKQIqnletekvggsskvsnltkelqgkEQKLLDLEKNLSAVNQVKDS 814
Cdd:COG3096    424 KarALCGLPDLTPENAEDYLA------AFRAKEQQA------------------------TEEVLELEQKLSVADAARRQ 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  815 LEKELQLLkEKFTSAVDGAENAQRAmQETINKLnqkeeqfalmsSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEn 894
Cdd:COG3096    474 FEKAYELV-CKIAGEVERSQAWQTA-RELLRRY-----------RSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLE- 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  895 diaEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQsqqetLKTHQEELKKMQDQL 974
Cdd:COG3096    540 ---EFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKE-----LAARAPAWLAAQDAL 611

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024460238  975 TDMKKQmetSQNQYKDLQakyeketsemitkhdaDIKGFKQNLLDAEEALKAAQkknDELETQAEELKKQAEQ 1047
Cdd:COG3096    612 ERLREQ---SGEALADSQ----------------EVTAAMQQLLEREREATVER---DELAARKQALESQIER 662
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 429-1136 7.08e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 7.08e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  429 LNQLEEEKRKVEDLQFRVEEEsitkgdlerkrqisedpenvatvseksrIMELERDLALRVKEVAELRGRLESSKhiddv 508
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTE----------------------------IKKKEKELEKLNNKYNDLKKQKEELE----- 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  509 DTSLSLLQEISSLQEKMAAAGKEHQRemsslKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKEnsdviel 588
Cdd:TIGR04523  173 NELNLLEKEKLNIQKNIDKIKNKLLK-----LELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQE------- 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  589 wKSKLESAIASHQQAMEELKVSFNKgvgaqtaefaeLKTQMEKVKLDYENemSNLKLKQENeksqhlKEIEALKAKLLEV 668
Cdd:TIGR04523  241 -INEKTTEISNTQTQLNQLKDEQNK-----------IKKQLSEKQKELEQ--NNKKIKELE------KQLNQLKSEISDL 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  669 TEEKEQ-TLENLKAKLESVEdqhlvemedtlnklqeaeikvKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDL----A 743
Cdd:TIGR04523  301 NNQKEQdWNKELKSELKNQE---------------------KKLEEIQNQISQNNKIISQLNEQISQLKKELTNSesenS 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  744 ALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNlsavnqvKDSLEKELQLLK 823
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE-------KELLEKEIERLK 432

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  824 EKFT---SAVDGAENAQRAMQETINKLNQK----EEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDI 896
Cdd:TIGR04523  433 ETIIknnSEIKDLTNQDSVKELIIKNLDNTreslETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKV 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  897 AEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANE--KAVQLQKNVEQTAQKAEQSQQEtlkthQEELKKMQDQL 974
Cdd:TIGR04523  513 KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFelKKENLEKEIDEKNKEIEELKQT-----QKSLKKKQEEK 587

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  975 TDMKKQMETSQNQYKDLQAKYEKETSEMitkhdadikgfkqnlldaEEALKAAQKKNDELETQAEELKKQAEQAKSLSSV 1054
Cdd:TIGR04523  588 QELIDQKEKEKKDLIKEIEEKEKKISSL------------------EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1055 LASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEA 1134
Cdd:TIGR04523  650 IKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDEFSKE 729


                   ..
gi 2024460238 1135 AE 1136
Cdd:TIGR04523  730 LE 731
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 743-1482 7.71e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.59  E-value: 7.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  743 AALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQkllDLEKNLSAVNQVKDSLEKELQLL 822
Cdd:TIGR00618  155 AQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTL---CTPCMPDTYHERKQVLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  823 KEkftsavdgaenAQRAMQETINKLNQKEEQFALMSS---ELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndIAEI 899
Cdd:TIGR00618  232 RE-----------ALQQTQQSHAYLTQKREAQEEQLKkqqLLKQLRARIEELRAQEAVLEETQERINRARKAAP--LAAH 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  900 MKSSGDSSAQLMKMNDELRLKERQLEQI--QLELTKANEKAVQLQKNVEQTAQKAEQ------SQQETLKTHQEELKKMQ 971
Cdd:TIGR00618  299 IKAVTQIEQQAQRIHTELQSKMRSRAKLlmKRAAHVKQQSSIEEQRRLLQTLHSQEIhirdahEVATSIREISCQQHTLT 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  972 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK--HDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK 1049
Cdd:TIGR00618  379 QHIHTLQQQKTTLTQKLQSLCKELDILQREQATIdtRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1050 SLSSVLASARKEIElmsdkmrDLISEKETLAQERNTLKLEKESLLSQHLEMESkiLLVQQDREELWTKNEELNSENKKIL 1129
Cdd:TIGR00618  459 IHLQESAQSLKERE-------QQLQTKEQIHLQETRKKAVVLARLLELQEEPC--PLCGSCIHPNPARQDIDNPGPLTRR 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1130 KQKEAAEAKSRQESTEKV-----ALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQK 1204
Cdd:TIGR00618  530 MQRGEQTYAQLETSEEDVyhqltSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDM 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1205 HIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEvSILTAERDSAQEKDLDLKSTHIALKneidc 1284
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQE-RVREHALSIRVLPKELLASRQLALQ----- 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1285 llqtnrSLQSEKEMLLKSREELcvslantaneNQALKLRKDEMQTELETEREkLEKMTKDNMDLKASLSSLSNFLEEMKS 1364
Cdd:TIGR00618  684 ------KMQSEKEQLTYWKEML----------AQCQTLLRELETHIEEYDRE-FNEIENASSSLGSDLAAREDALNQSLK 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1365 SREASNSEKIHLLQEALFASEQRLL------AEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS 1438
Cdd:TIGR00618  747 ELMHQARTVLKARTEAHFNNNEEVTaalqtgAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETL 826

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 2024460238 1439 LQFEKHNEALLREKD----ELERKYSELLDEKKSLENAFSDMKREQEL 1482
Cdd:TIGR00618  827 VQEEEQFLSRLEEKSatlgEITHQLLKYEECSKQLAQLTQEQAKIIQL 874
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
668-1243 9.51e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.28  E-value: 9.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  668 VTEEKEQTLENLKAKLESVEDQHLVEmedtlnKLQEAEIKVKELDVLQAKCNEQTkligsltqqiRASEEKLLDLAALQK 747
Cdd:PRK02224   181 VLSDQRGSLDQLKAQIEEKEEKDLHE------RLNGLESELAELDEEIERYEEQR----------EQARETRDEADEVLE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  748 ANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFT 827
Cdd:PRK02224   245 EHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  828 SAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSS 907
Cdd:PRK02224   325 ELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  908 AQLMKMND----------ELRLKERQLEQIQLELTKANEKAVQLQK--NVEQTAQKAEQSQQ-ETLKTHQEELKKMQDQL 974
Cdd:PRK02224   405 VDLGNAEDfleelreerdELREREAELEATLRTARERVEEAEALLEagKCPECGQPVEGSPHvETIEEDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  975 TDMKKQMETSQNQYKdlQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKslsSV 1054
Cdd:PRK02224   485 EDLEEEVEEVEERLE--RAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKR---EA 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1055 LASARKEIELMSDKMRDLISEKETLAQERNTLKlEKESLLSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEa 1134
Cdd:PRK02224   560 AAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREAL----AELNDERRERLAEKR- 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1135 aEAKSRQESTEKVALISEkskLLSEIETAQADLLKITQENDALRSSESTLLQQLKelqankdavdvACQKHIKEREELEH 1214
Cdd:PRK02224   634 -ERKRELEAEFDEARIEE---AREDKERAEEYLEQVEEKLDELREERDDLQAEIG-----------AVENELEELEELRE 698

                          570       580
                   ....*....|....*....|....*....
gi 2024460238 1215 YQKLLEENDRVIKDKDDVIQRLQSSYDDL 1243
Cdd:PRK02224   699 RREALENRVEALEALYDEAEELESMYGDL 727
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1457-2031 1.02e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1457 RKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTtlkysIEALEEELKKKNLENQELIACRSDLSDLLKEAQDAR 1536
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAE-----LEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1537 RTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNn 1616
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE- 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1617 igfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSC 1696
Cdd:COG1196    370 ---AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1697 VSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLvIINEEILKEKEKLSKEYYKLHE------KVVALLEQTDADFSC 1770
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAEL-LEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGA 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1771 RLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNE 1850
Cdd:COG1196    526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1851 KLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLA-ALQEENVKLAEELGRSRDEVTSH 1929
Cdd:COG1196    606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSlTGGSRRELLAALLEAEAELEELA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1930 QKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTL 2009
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765

                          570       580
                   ....*....|....*....|..
gi 2024460238 2010 QSVVKtlesdklKLEEKVKNLE 2031
Cdd:COG1196    766 ERELE-------RLEREIEALG 780
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 762-962 1.05e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 53.30  E-value: 1.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  762 QLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQ 841
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  842 ETINKLNQKEeqFALMSSELEQLKSNLTVMET-------KLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN 914
Cdd:COG3883     97 RSGGSVSYLD--VLLGSESFSDFLDRLSALSKiadadadLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2024460238  915 DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKT 962
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1496-2018 1.15e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1496 TLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLEnelaavshakqVLSSSFNTCSSDIEILNRERTELQ 1575
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-----------TLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1576 DKCQKLTGEVENMKENLT---VEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKL 1652
Cdd:PRK02224   279 EEVRDLRERLEELEEERDdllAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1653 EEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSL 1732
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1733 viinEEILKEKEKLskeyykLHEKVVALLEQT--DADFSCRLLVSEGKHELLLEEMSNLALKLREIE-RLQAQTFMQKFE 1809
Cdd:PRK02224   439 ----RERVEEAEAL------LEAGKCPECGQPveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEeRLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1810 AD-KRAEEVLQTMEKVTKEKDAIHQEKIETLASLensRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1888
Cdd:PRK02224   509 DRiERLEERREDLEELIAERRETIEEKRERAEEL---RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELK 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1889 KEFEALK------LAAAQKSQQLAALQEENVKLAEELGRSRDEVTS----HQKLEEERSVLNNQLLEMKKSLPSNTLRES 1958
Cdd:PRK02224   586 ERIESLErirtllAAIADAEDEIERLREKREALAELNDERRERLAEkrerKRELEAEFDEARIEEAREDKERAEEYLEQV 665

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1959 TLK-KEIDEERASLQKSIsdtsALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLES 2018
Cdd:PRK02224   666 EEKlDELREERDDLQAEI----GAVENELEELEELRERREALENRVEALEALYDEAEELES 722
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
626-1124 1.49e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  626 KTQMEKVKLDYENEMSNLKLKQENEKSQHLKE-IEALKAKLLEVTEEKE----------QTLENLKAKLESVED--QHLV 692
Cdd:PRK02224   175 RLGVERVLSDQRGSLDQLKAQIEEKEEKDLHErLNGLESELAELDEEIEryeeqreqarETRDEADEVLEEHEErrEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  693 EMEDTLNKLQEA-EIKVKELDVLQAKCNEQTKLIGSLTQQI----------RASEEKLLD-LAALQKANSEGKLEIQKLS 760
Cdd:PRK02224   255 TLEAEIEDLRETiAETEREREELAEEVRDLRERLEELEEERddllaeagldDADAEAVEArREELEDRDEELRDRLEECR 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  761 EQLQAAEKQIQN-------LETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAvnqvkdsLEKELQLLKEKFTSAVDGA 833
Cdd:PRK02224   335 VAAQAHNEEAESlredaddLEERAEELREEAAELESELEEAREAVEDRREEIEE-------LEEEIEELRERFGDAPVDL 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  834 ENAqramqetinklnqkEEQFALMSSELEQLKSNLTVMETKLKEREER----EQQLTEAKV-KLENDI--AEIMKSSGDS 906
Cdd:PRK02224   408 GNA--------------EDFLEELREERDELREREAELEATLRTARERveeaEALLEAGKCpECGQPVegSPHVETIEED 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  907 SAQLMKMNDELRLKERQLEQIQLELTKAnEKAVQLQKNVEQTAQKAEQSqQETLKTHQEELKKMQDQLTDMKKQMEtsqn 986
Cdd:PRK02224   474 RERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDL-EELIAERRETIEEKRERAEELRERAA---- 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  987 qykDLQAKYEKETSEMITKHDAdikgfkqnlldAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSvLASARKEIELMS 1066
Cdd:PRK02224   548 ---ELEAEAEEKREAAAEAEEE-----------AEEAREEVAELNSKLAELKERIESLERIRTLLAA-IADAEDEIERLR 612

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238 1067 DKmRDLISEKETLAQERNTLKLEKESLLSQHLEmESKILLVQQDREELWTKNEELNSE 1124
Cdd:PRK02224   613 EK-REALAELNDERRERLAEKRERKRELEAEFD-EARIEEAREDKERAEEYLEQVEEK 668
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
967-1517 1.70e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  967 LKKMQDQLTDMKKQMEtsQNQYKDLQAK---YEKETSEMitkhDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKK 1043
Cdd:PRK02224   182 LSDQRGSLDQLKAQIE--EKEEKDLHERlngLESELAEL----DEEIERYEEQREQARETRDEADEVLEEHEERREELET 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1044 QAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL-------KLEKESLLSQHLEMESKILLVQQDREELWT 1116
Cdd:PRK02224   256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLlaeagldDADAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1117 KNEELNSENKKILkqKEAAEAKSRQESTEkvaliSEKSKLLSEIETAQADLLKITQENDALRSsestllqqlkELQANKD 1196
Cdd:PRK02224   336 AAQAHNEEAESLR--EDADDLEERAEELR-----EEAAELESELEEAREAVEDRREEIEELEE----------EIEELRE 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1197 AVDVACQkhikEREELEHYQKLLEEN-DRVIKDKDDVIQRLQSSYDDLARNQR--------ELLQEVS----ILTAERDS 1263
Cdd:PRK02224   399 RFGDAPV----DLGNAEDFLEELREErDELREREAELEATLRTARERVEEAEAlleagkcpECGQPVEgsphVETIEEDR 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1264 AQEKDL-----DLKSTHIALKNEIDcLLQTNRSLQSEKEMLLKSRE---ELCVSLANTANEN----QALKLRKDEMQTEL 1331
Cdd:PRK02224   475 ERVEELeaeleDLEEEVEEVEERLE-RAEDLVEAEDRIERLEERREdleELIAERRETIEEKreraEELRERAAELEAEA 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1332 ETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNS-EKIHLLQEALFASEQRLLAEREELVNENKAVTEKL-TKA 1409
Cdd:PRK02224   554 EEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERiRTLLAAIADAEDEIERLREKREALAELNDERRERLaEKR 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1410 TADAVLAETAFTEKINELNLEKEsvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR-EQELDFSAKR 1488
Cdd:PRK02224   634 ERKRELEAEFDEARIEEAREDKE-------RAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElRERREALENR 706

                          570       580       590
                   ....*....|....*....|....*....|....
gi 2024460238 1489 L-----LVQENTTLKYSIEALEEELKKKNLENQE 1517
Cdd:PRK02224   707 VealeaLYDEAEELESMYGDLRAELRQRNVETLE 740
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1361-2040 2.05e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.43  E-value: 2.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1361 EMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS-- 1438
Cdd:TIGR00618  179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkk 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1439 -------------LQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE----QELDFSAKRLLVQENTTLKYSI 1501
Cdd:TIGR00618  259 qqllkqlrarieeLRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIhtelQSKMRSRAKLLMKRAAHVKQQS 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1502 EALEEELKKKNLENQE-LIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRErtelQDKCQK 1580
Cdd:TIGR00618  339 SIEEQRRLLQTLHSQEiHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQRE----QATIDT 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1581 LTGEVENMKENLTVEKKARVLDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEK---EKSETKLEEVIK 1657
Cdd:TIGR00618  415 RTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEqihLQETRKKAVVLA 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1658 EKMILYKETEQLASKIEQLKSDFTSLSVSKA------ELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKS 1731
Cdd:TIGR00618  495 RLLELQEEPCPLCGSCIHPNPARQDIDNPGPltrrmqRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSI 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1732 LVIINEEILKEKEKLSKEyyklhekVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEAD 1811
Cdd:TIGR00618  575 LTQCDNRSKEDIPNLQNI-------TVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTA 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1812 KRAEEVLQTMEKVTKEKDAIHQEKIETLASlensrqtNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEF 1891
Cdd:TIGR00618  648 LHALQLTLTQERVREHALSIRVLPKELLAS-------RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1892 EALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKeidEERASL 1971
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFN---RLREED 797

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1972 QKSISDTSALITQK--DEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQ 2040
Cdd:TIGR00618  798 THLLKTLEAEIGQEipSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQ 868
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 406-1517 3.26e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 52.75  E-value: 3.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  406 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgDLERKrQISEDPENVatvseksRIMELERDL 485
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIK-------DLFDK-YLEIDDEII-------YINKLKLEL 605

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  486 ALRVKEVAE----LRGRLESSKHIDDVDTSLSLLQEISSLQ--EKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSA 559
Cdd:TIGR01612  606 KEKIKNISDkneyIKKAIDLKKIIENNNAYIDELAKISPYQvpEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVK 685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  560 SNERMGKEN----ESLKTKLDHA-----NKENSDV------IELWKSKLESAIASHQQAME-ELKVSFNKGVGAQTAEFA 623
Cdd:TIGR01612  686 ENAIDNTEDkaklDDLKSKIDKEydkiqNMETATVelhlsnIENKKNELLDIIVEIKKHIHgEINKDLNKILEDFKNKEK 765

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  624 ELKTQMEKVKlDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAkLESVEDQHLVEMEDTLNKLQE 703
Cdd:TIGR01612  766 ELSNKINDYA-KEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKT-ISIKEDEIFKIINEMKFMKDD 843

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  704 AEIKVKELDVLQAKCNEQT----KLIGSLTQQIRA--SEEKLLDLAalQKANSEGKLeiqkLSEQLQAAEKQIQNLET-E 776
Cdd:TIGR01612  844 FLNKVDKFINFENNCKEKIdsehEQFAELTNKIKAeiSDDKLNDYE--KKFNDSKSL----INEINKSIEEEYQNINTlK 917

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  777 KVGGSSKVSNLTKElqgkeqkllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFAL 856
Cdd:TIGR01612  918 KVDEYIKICENTKE---------SIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDASL 988

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  857 MSSE---------LEQLKSNL-----TVMETKLKEREEREQQLTEAKVKLENDIAEI-------MKSSGDSSAQLMKMND 915
Cdd:TIGR01612  989 NDYEaknnelikyFNDLKANLgknkeNMLYHQFDEKEKATNDIEQKIEDANKNIPNIeiaihtsIYNIIDEIEKEIGKNI 1068

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  916 ELrLKERQLEQIQLELTKANEKAVQLqknveQTAQKAEQSQQETLKtHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKY 995
Cdd:TIGR01612 1069 EL-LNKEILEEAEINITNFNEIKEKL-----KHYNFDDFGKEENIK-YADEINKIKDDIKNLDQKIDHHIKALEEIKKKS 1141

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  996 EKETSEMITKHDaDIKGFKQNLLdAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLAsarkEIELMSDKMRDLISE 1075
Cdd:TIGR01612 1142 ENYIDEIKAQIN-DLEDVADKAI-SNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIA----EIEKDKTSLEEVKGI 1215

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1076 KETLAQERNTLKLEK---ESLLSQHL--EMESKIllvqQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALI 1150
Cdd:TIGR01612 1216 NLSYGKNLGKLFLEKideEKKKSEHMikAMEAYI----EDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHI 1291

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1151 SEKS--KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQK-----------HIKE-REELEHYQ 1216
Cdd:TIGR01612 1292 ISKKhdENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEianiynilklnKIKKiIDEVKEYT 1371

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1217 KLLEENDRVIKDKDDVIQRL-QSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSE 1295
Cdd:TIGR01612 1372 KEIEENNKNIKDELDKSEKLiKKIKDDINLEECKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNEN 1451

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1296 KEMLLKSREelcvsLANTANEnQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIH 1375
Cdd:TIGR01612 1452 VLLLFKNIE-----MADNKSQ-HILKIKKDNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTE 1525

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1376 LLQEalfASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREK--- 1452
Cdd:TIGR01612 1526 LLNK---YSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQlsl 1602

                         1130      1140      1150      1160      1170      1180      1190
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1453 DELERKYSELLDEKKSLENAFSDM----KREQELDFSAKRLLVQENTTLKYSIEALEEELK--KKNLENQE 1517
Cdd:TIGR01612 1603 ENFENKFLKISDIKKKINDCLKETesieKKISSFSIDSQDTELKENGDNLNSLQEFLESLKdqKKNIEDKK 1673
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 702-1224 3.62e-06

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 52.45  E-value: 3.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  702 QEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 781
Cdd:pfam07111   63 QQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQREL 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  782 SKVSNLTKELQGKEQKLLdlEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSEL 861
Cdd:pfam07111  143 EEIQRLHQEQLSSLTQAH--EEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLV 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  862 EQLKSNL---TVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQL-------------- 924
Cdd:pfam07111  221 ESLRKYVgeqVPPEVHSQTWELERQELLDTMQHLQEDRADLQATVELLQVRVQSLTHMLALQEEELtrkiqpsdslepef 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  925 -EQIQLELTKANEKAVQLQknVEQTAQKAEQSqqETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM- 1002
Cdd:pfam07111  301 pKKCRSLLNRWREKVFALM--VQLKAQDLEHR--DSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAk 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1003 -----ITKHDADIKGFKQNLLDAEEALK----AAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIElmsdKMRDLI 1073
Cdd:pfam07111  377 glqmeLSRAQEARRRQQQQTASAEEQLKfvvnAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVH----TIKGLM 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1074 SEKETLAQerntLKLEKESLLSQHLEMESKILL-VQQDREELWTKNEELNSENKKIlkQKEAAEAKSRQEStEKVALISE 1152
Cdd:pfam07111  453 ARKVALAQ----LRQESCPPPPPAPPVDADLSLeLEQLREERNRLDAELQLSAHLI--QQEVGRAREQGEA-ERQQLSEV 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1153 KSKLLSEIETAQADLLKITQENDALRSSESTLLQQL----KELQANKDAVDVACQKHIKE-----REELEHYQKLLEEND 1223
Cdd:pfam07111  526 AQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAaslrQELTQQQEIYGQALQEKVAEvetrlREQLSDTKRRLNEAR 605


                   .
gi 2024460238 1224 R 1224
Cdd:pfam07111  606 R 606
COG5022 COG5022
Myosin heavy chain [General function prediction only];
635-1395 6.10e-06

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 51.62  E-value: 6.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  635 DYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKA----KLESVEDQHLVEMEDTLNKLQEAEIKVKE 710
Cdd:COG5022    814 SYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRfsllKKETIYLQSAQRVELAERQLQELKIDVKS 893

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  711 LDVLQAKCNEQTKLIGSLTQQIRASeeklldlaalqkansegkleiqkLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK- 789
Cdd:COG5022    894 ISSLKLVNLELESEIIELKKSLSSD-----------------------LIENLEFKTELIARLKKLLNNIDLEEGPSIEy 950

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  790 ELQGKEQKLLDLEKNLSAVNQVKDSLEKElqllkekftsavdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLT 869
Cdd:COG5022    951 VKLPELNKLHEVESKLKETSEEYEDLLKK---------------------STILVREGNKANSELKNFKKELAELSKQYG 1009

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  870 VMETKLKEREEREQQLTEakvkLENDIAeIMKSSGDSSAQLMKMNDELRLKERQLEQiqlelTKANEKAVQLQknveqta 949
Cdd:COG5022   1010 ALQESTKQLKELPVEVAE----LQSASK-IISSESTELSILKPLQKLKGLLLLENNQ-----LQARYKALKLR------- 1072

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  950 qkaeqsqqetlkthqeelKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemitkhdaDIKGFKQNLLDAEEAL---KA 1026
Cdd:COG5022   1073 ------------------RENSLLDDKQLYQLESTENLLKTINVK--------------DLEVTNRNLVKPANVLqfiVA 1120

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1027 AQKKNDELetqaEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILL 1106
Cdd:COG5022   1121 QMIKLNLL----QEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSS 1196

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1107 VQQdrEELWTKNEELNSENKKILKQkeaaeAKSRQESTEKVALISEKSKLLSEIEtaQADLLKITQENdalRSSEStLLQ 1186
Cdd:COG5022   1197 SEV--NDLKNELIALFSKIFSGWPR-----GDKLKKLISEGWVPTEYSTSLKGFN--NLNKKFDTPAS---MSNEK-LLS 1263

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1187 QLKELQankdavDVACQKHIKEREELEHYQKLLEENDrvikdkddviqrlQSSYDDLARNQRELLQEVSiLTAERDSAQE 1266
Cdd:COG5022   1264 LLNSID------NLLSSYKLEEEVLPATINSLLQYIN-------------VGLFNALRTKASSLRWKSA-TEVNYNSEEL 1323

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1267 KDLDLKSTHIALKNEIDCLLQTNRSLQSEKEML--LKSREELCVSLANTanENQALKLRKDEMQTELETEREKLEKMTKD 1344
Cdd:COG5022   1324 DDWCREFEISDVDEELEELIQAVKVLQLLKDDLnkLDELLDACYSLNPA--EIQNLKSRYDPADKENNLPKEILKKIEAL 1401

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1345 NMDLKASLSSLSnFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREEL 1395
Cdd:COG5022   1402 LIKQELQLSLEG-KDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSLSAL 1451
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 336-1005 8.00e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 51.26  E-value: 8.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  336 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLaERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDqlr 415
Cdd:pfam05483  159 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE--- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  416 amVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEdpENVATVSEKSRIMELE-RDLALRVKEVAE 494
Cdd:pfam05483  235 --INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQD--ENLKELIEKKDHLTKElEDIKMSLQRSMS 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  495 LRGRLESSKHIDdVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEiktlsasNERMGKENESLKTK 574
Cdd:pfam05483  311 TQKALEEDLQIA-TKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE-------QQRLEKNEDQLKII 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  575 LDHANKENSDVIELWKSKlesaiASHQQAMEELKVsfnkgVGAQTAEFAELKTQMEKVKLDYENEMSNLK-LKQENEKSQ 653
Cdd:pfam05483  383 TMELQKKSSELEEMTKFK-----NNKEVELEELKK-----ILAEDEKLLDEKKQFEKIAEELKGKEQELIfLLQAREKEI 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  654 HLKEIEALKAKLLE---VTEEKEQTLENLKAKLESVEDQHLVEMEDTLNK--LQEAEIKVKELDVLQAKCNEQTKLIGSL 728
Cdd:pfam05483  453 HDLEIQLTAIKTSEehyLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKelTQEASDMTLELKKHQEDIINCKKQEERM 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  729 TQQIRASEEKLLDL--------AALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLD 800
Cdd:pfam05483  533 LKQIENLEEKEMNLrdelesvrEEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEE 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  801 LEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLnQKEEQFALMSSEleqlksnltvmetKLKEREE 880
Cdd:pfam05483  613 LHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNY-QKEIEDKKISEE-------------KLLEEVE 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  881 REQQLTEAKVKLENDIaeimkssgdssaqlmkmndELRLKERQLEQIQL-ELTKANEKAVQLQKNVEQTAQKAEQSQQET 959
Cdd:pfam05483  679 KAKAIADEAVKLQKEI-------------------DKRCQHKIAEMVALmEKHKHQYDKIIEERDSELGLYKNKEQEQSS 739

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2024460238  960 LKTHQE-ELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK 1005
Cdd:pfam05483  740 AKAALEiELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 580-1963 9.22e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.21  E-value: 9.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  580 KENSDVIELWKSKLESAIASHQQAMEELKVSFN----KGVGAQTAEFAELKTQMEKVKLDYenemsNLKLKQENEKSQHL 655
Cdd:TIGR01612  503 KDFKDIIDFMELYKPDEVPSKNIIGFDIDQNIKaklyKEIEAGLKESYELAKNWKKLIHEI-----KKELEEENEDSIHL 577

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  656 -KEIEALKAKLLEVTEE----KEQTLEnLKAKLESVED--QHLVEMEDTLNKLQEAEIKVKELDVLQA-KCNEQTKLIGS 727
Cdd:TIGR01612  578 eKEIKDLFDKYLEIDDEiiyiNKLKLE-LKEKIKNISDknEYIKKAIDLKKIIENNNAYIDELAKISPyQVPEHLKNKDK 656

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  728 LTQQIRASEEKLL--DLAALQKA-----------NSEGKLEIQKLSEQLQAAEKQIQNLETEKVGgsskvSNLTKeLQGK 794
Cdd:TIGR01612  657 IYSTIKSELSKIYedDIDALYNElssivkenaidNTEDKAKLDDLKSKIDKEYDKIQNMETATVE-----LHLSN-IENK 730

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  795 EQKLLDLEKNLSavNQVKDSLEKELQLLKEKFtsavdgaENAQRAMQETINKLNQKEEQFALMSSELEQLKSNL------ 868
Cdd:TIGR01612  731 KNELLDIIVEIK--KHIHGEINKDLNKILEDF-------KNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYndqini 801

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  869 -TVMETKLKEREEREQQLTEAKVKLENDIAEIMKssgdssaQLMKMNDELrlkerqleqiqleLTKANeKAVQLQKNVEQ 947
Cdd:TIGR01612  802 dNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIIN-------EMKFMKDDF-------------LNKVD-KFINFENNCKE 860

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  948 TAQKAEQSQQETLKTHQEELKkmQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADikGFKQNLLDAEEALKAA 1027
Cdd:TIGR01612  861 KIDSEHEQFAELTNKIKAEIS--DDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVD--EYIKICENTKESIEKF 936

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1028 QKKNDELEtqaEELKKQAEQAKSLSSVLASARKEIElmsdkmrdlisekETLAQERNTL-KLEKESLLSQHLEMESKILL 1106
Cdd:TIGR01612  937 HNKQNILK---EILNKNIDTIKESNLIEKSYKDKFD-------------NTLIDKINELdKAFKDASLNDYEAKNNELIK 1000

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1107 VQQDREELWTKNEElnsenkKILKQKEAAEAKSRQESTEKvalISEKSKLLSEIETA-QADLLKITQENDAL--RSSEST 1183
Cdd:TIGR01612 1001 YFNDLKANLGKNKE------NMLYHQFDEKEKATNDIEQK---IEDANKNIPNIEIAiHTSIYNIIDEIEKEigKNIELL 1071

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1184 LLQQLKELQANkdavdVACQKHIKEREELEHYQKLLEENDrvIKDKDDViqrlQSSYDDLARNQRELLQEVSILTAERDS 1263
Cdd:TIGR01612 1072 NKEILEEAEIN-----ITNFNEIKEKLKHYNFDDFGKEEN--IKYADEI----NKIKDDIKNLDQKIDHHIKALEEIKKK 1140

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1264 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMllksrEELCVSLANTANENQALKLRKDEMqTELETEREKLEKMTK 1343
Cdd:TIGR01612 1141 SENYIDEIKAQINDLEDVADKAISNDDPEEIEKKI-----ENIVTKIDKKKNIYDEIKKLLNEI-AEIEKDKTSLEEVKG 1214

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1344 DNMDLKASLSSLsnFLEEMKSSREASnsekihllqEALFASEQRLLAEREELvnenkavtEKLTKATADAVLAETAFTEK 1423
Cdd:TIGR01612 1215 INLSYGKNLGKL--FLEKIDEEKKKS---------EHMIKAMEAYIEDLDEI--------KEKSPEIENEMGIEMDIKAE 1275

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1424 INELNLEKESVFSKSLQFEKHNEAL--LREKD----ELERKYSELLDEKKSLENAFSDMKREQeldfSAKRLLVQENTTL 1497
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENIsdIREKSlkiiEDFSEESDINDIKKELQKNLLDAQKHN----SDINLYLNEIANI 1351

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1498 kYSIEALEeelKKKNLENQeliacrsdLSDLLKEAQDARRTLENELAAVSHAKQVL--SSSFNTCSSDIEilnrerTELQ 1575
Cdd:TIGR01612 1352 -YNILKLN---KIKKIIDE--------VKEYTKEIEENNKNIKDELDKSEKLIKKIkdDINLEECKSKIE------STLD 1413

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1576 DKcqKLTGEVENMKENltvekKARVLDKES----FLLERMELQNNIGFLEKEVEEMREKNKEFLTEKE------------ 1639
Cdd:TIGR01612 1414 DK--DIDECIKKIKEL-----KNHILSEESnidtYFKNADENNENVLLLFKNIEMADNKSQHILKIKKdnatndhdfnin 1486

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1640 LLVQEKEKSETKLEEVIKEKmilyKETEQLASKIEQLKSDFTSLSVSKAELedvhscvsvmldELQHKYEVTEKEKMELV 1719
Cdd:TIGR01612 1487 ELKEHIDKSKGCKDEADKNA----KAIEKNKELFEQYKKDVTELLNKYSAL------------AIKNKFAKTKKDSEIII 1550

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1720 QENESLHaewKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLleEMSNLALK----LRE 1795
Cdd:TIGR01612 1551 KEIKDAH---KKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFL--KISDIKKKindcLKE 1625

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1796 IERLQAQ-------TFMQKFEADKRAEEVLQT-MEKVTKEKDAIHQEKIEtlasLENSRQTNEKLQNELDMLKQN----- 1862
Cdd:TIGR01612 1626 TESIEKKissfsidSQDTELKENGDNLNSLQEfLESLKDQKKNIEDKKKE----LDELDSEIEKIEIDVDQHKKNyeigi 1701

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1863 -------NLKNEEELTKSKELLnleNKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEE 1935
Cdd:TIGR01612 1702 iekikeiAIANKEEIESIKELI---EPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSK 1778

                         1450      1460
                   ....*....|....*....|....*...
gi 2024460238 1936 RSVLNNQLLEMKKSLPSNTLRESTLKKE 1963
Cdd:TIGR01612 1779 EPITYDEIKNTRINAQNEFLKIIEIEKK 1806
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1044-1267 1.01e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1044 QAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNS 1123
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1124 ---ENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEN-DALRSSESTLLQQLKELQANKDAVD 1199
Cdd:COG4942     98 eleAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQaEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238 1200 VACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEK 1267
Cdd:COG4942    178 ALLAELEEERAALE---ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
mukB PRK04863
chromosome partition protein MukB;
587-1339 1.04e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.11  E-value: 1.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  587 ELWKSKleSAIASHQQAMEELKvsfnkgvgaqtAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQhlKEIEALKAKLL 666
Cdd:PRK04863   294 ELYTSR--RQLAAEQYRLVEMA-----------RELAELNEAESDLEQDYQAASDHLNLVQTALRQQ--EKIERYQADLE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  667 EVTEEkeqtlenLKAKLESVEDQHLvEMEDTLNKLQEAEIKVKEL-----DVLQAKCNEQTKLIgSLTQQIRASEE--KL 739
Cdd:PRK04863   359 ELEER-------LEEQNEVVEEADE-QQEENEARAEAAEEEVDELksqlaDYQQALDVQQTRAI-QYQQAVQALERakQL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  740 LDLAALQKANSEGKLEiqklseQLQAAEKQIqnletekvggsskvsnltkelqgkEQKLLDLEKNLSAVNQVKDSLEKEL 819
Cdd:PRK04863   430 CGLPDLTADNAEDWLE------EFQAKEQEA------------------------TEELLSLEQKLSVAQAAHSQFEQAY 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  820 QLLKekftsAVDGAENAQRAMQETINKLNQKEEQFALmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKL---ENDI 896
Cdd:PRK04863   480 QLVR-----KIAGEVSRSEAWDVARELLRRLREQRHL-AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLgknLDDE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  897 AEIMKSSGDSSAQLMKMNDELR-LKER------QLEQIQLELTK----------ANEKAVQLQknvEQTAQKAEQSQQ-- 957
Cdd:PRK04863   554 DELEQLQEELEARLESLSESVSeARERrmalrqQLEQLQARIQRlaarapawlaAQDALARLR---EQSGEEFEDSQDvt 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  958 ETLKTHQEELKKMQ---DQLTDMKKQMEtsqNQYKDLQAKYEKETSEM------------------ITKHDA-------- 1008
Cdd:PRK04863   631 EYMQQLLERERELTverDELAARKQALD---EEIERLSQPGGSEDPRLnalaerfggvllseiyddVSLEDApyfsalyg 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1009 ---------------------------------DIKGFKQNLLDAEEALKA-AQKKND-EL----------------ETQ 1037
Cdd:PRK04863   708 parhaivvpdlsdaaeqlagledcpedlyliegDPDSFDDSVFSVEELEKAvVVKIADrQWrysrfpevplfgraarEKR 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1038 AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLA---------QERNTLKLEKESLLSQHlemESKIllvQ 1108
Cdd:PRK04863   788 IEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfeadpeaelRQLNRRRVELERALADH---ESQE---Q 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1109 QDREELWTKNEELNSENK-----KILK----QKEAAEAKSRQESTEKVAL-ISEKSKLLSEIETAQADLLKITQENDALR 1178
Cdd:PRK04863   862 QQRSQLEQAKEGLSALNRllprlNLLAdetlADRVEEIREQLDEAEEAKRfVQQHGNALAQLEPIVSVLQSDPEQFEQLK 941

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1179 SSESTLLQQLKELQANKDAVD--VACQKH-----------------IKEREELEHYQKLLEENDRVIKDKDD-------V 1232
Cdd:PRK04863   942 QDYQQAQQTQRDAKQQAFALTevVQRRAHfsyedaaemlaknsdlnEKLRQRLEQAEQERTRAREQLRQAQAqlaqynqV 1021

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1233 IQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKsthialKNEIDCLLQTNRSLQSEKEMLLKSREElcvslan 1312
Cdd:PRK04863  1022 LASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARAR------RDELHARLSANRSRRNQLEKQLTFCEA------- 1088

                          890       900
                   ....*....|....*....|....*..
gi 2024460238 1313 tANENQALKLRKdeMQTELETEREKLE 1339
Cdd:PRK04863  1089 -EMDNLTKKLRK--LERDYHEMREQVV 1112
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1658-2047 1.11e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.51  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1658 EKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvhSCVSVMLDELQHKYEVTEKEKMELVQ--ENESLHAEwkslvii 1735
Cdd:pfam17380  234 EKMERRKESFNLAEDVTTMTPEYTVRYNGQTMTEN--EFLNQLLHIVQHQKAVSERQQQEKFEkmEQERLRQE------- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1736 NEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELlleEMSNLALKLREIERLQAQTFMQKFEADKRAE 1815
Cdd:pfam17380  305 KEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMEREREL---ERIRQEERKRELERIRQEEIAMEISRMRELE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1816 ----EVLQTMEKVTKEKDAIHQEKIetlasLENSRQTNEKLQneldMLKQNNLKNEEELTKSKELLNLEnkkvEELKKEF 1891
Cdd:pfam17380  382 rlqmERQQKNERVRQELEAARKVKI-----LEEERQRKIQQQ----KVEMEQIRAEQEEARQREVRRLE----EERAREM 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1892 EALKLAAAQKSQQLAAL-QEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERAS 1970
Cdd:pfam17380  449 ERVRLEEQERQQQVERLrQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKA 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1971 L----QKSISDTSALITQKDEELEKLRNEITVLRGEnasaktlQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTS 2046
Cdd:pfam17380  529 IyeeeRRREAEEERRKQQEMEERRRIQEQMRKATEE-------RSRLEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   .
gi 2024460238 2047 P 2047
Cdd:pfam17380  602 P 602
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1666-2015 1.23e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1666 TEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQH------KYEVTEKEKMELvqENESLHAEWKSLVIINEEI 1739
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRerekaeRYQALLKEKREY--EGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1740 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsegkHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRA----- 1814
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEE------------IEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASlersi 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1815 EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKqnnlkneEELTKSKELLNLENKKVEELKKEFEAL 1894
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT-------EEYAELKEELEDLRAELEEVDKEFAET 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1895 KLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDE---ERASL 1971
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEEL---QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKqewKLEQL 460

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 2024460238 1972 QKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2015
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 605-819 1.28e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 50.44  E-value: 1.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  605 EELKVSFNKgvgaqtaEFAELKTQMEKVKLDYENEMSNL--KLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAK 682
Cdd:pfam13166  271 AALEAHFDD-------EFTEFQNRLQKLIEKVESAISSLlaQLPAVSDLASLLSAFELDVEDIESEAEVLNSQLDGLRRA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  683 LESVEDQ--HLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLdlaalqkaNSEGKLEIQKLS 760
Cdd:pfam13166  344 LEAKRKDpfKSIELDSVDAKIESINDLVASINELIAKHNEITDNFEEEKNKAKKKLRLHL--------VEEFKSEIDEYK 415

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460238  761 EQLQAAEKQIQNLETEKvggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKEL 819
Cdd:pfam13166  416 DKYAGLEKAINSLEKEI-------KNLEAEIKKLREEIKELEAQLRDHKPGADEINKLL 467
PRK01156 PRK01156
chromosome segregation protein; Provisional
 378-901 1.32e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 1.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  378 EVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADR--EKVELLNQLEEEKRKVE-DLQFRVEEESITKG 454
Cdd:PRK01156   198 ELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNElsSLEDMKNRYESEIKTAEsDLSMELEKNNYYKE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  455 DLERKRQIsedpENVATVSEKSRIME---LERDLALRVKEVAELRGRLESskhIDDVDTSLSLLQEISSLQEKMAAAGKE 531
Cdd:PRK01156   278 LEERHMKI----INDPVYKNRNYINDyfkYKNDIENKKQILSNIDAEINK---YHAIIKKLSVLQKDYNDYIKKKSRYDD 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  532 HQREMSSLKEkFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESaIASHQQAMEELKVSF 611
Cdd:PRK01156   351 LNNQILELEG-YEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNE-INVKLQDISSKVSSL 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  612 NKGVGAQTAEFAELKTQME---------------------KVKLDYENEMSNLKLK---QENEKSQHLKEIEALKAKLLE 667
Cdd:PRK01156   429 NQRIRALRENLDELSRNMEmlngqsvcpvcgttlgeeksnHIINHYNEKKSRLEEKireIEIEVKDIDEKIVDLKKRKEY 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  668 VTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKVKELDVlQAKCNEQTKLIGSLTQQIRA-SEEKLLDLAALQ 746
Cdd:PRK01156   509 LESEEINKSINEYNKIESARAD-LEDIKIKINELKDKHDKYEEIKN-RYKSLKLEDLDSKRTSWLNAlAVISLIDIETNR 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  747 KANSEgkleiqkLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQgKEQKLLDLEKNLSavnQVKDSLEKELQLLKEKF 826
Cdd:PRK01156   587 SRSNE-------IKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIE-NEANNLNNKYNEI---QENKILIEKLRGKIDNY 655

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238  827 TSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 901
Cdd:PRK01156   656 KKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
669-889 1.38e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.40  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  669 TEEKEQTLENLKAKLESVEDQhlvemedtlnkLQEAEIKVKELdvlqakcnEQTKLIGSLTQQIRASEEKLldlAALQKA 748
Cdd:COG3206    170 REEARKALEFLEEQLPELRKE-----------LEEAEAALEEF--------RQKNGLVDLSEEAKLLLQQL---SELESQ 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  749 NSEGKLEIQKLSEQLQAAEKQIQNLETE--KVGGSSKVSNLTKELQGKEQKLLDLEKNLSA-----------VNQVKDSL 815
Cdd:COG3206    228 LAEARAELAEAEARLAALRAQLGSGPDAlpELLQSPVIQQLRAQLAELEAELAELSARYTPnhpdvialraqIAALRAQL 307

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024460238  816 EKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAK 889
Cdd:COG3206    308 QQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
656-890 1.55e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  656 KEIEALKAKLlevtEEKEQTLENLKAKLESVEDQhlVEMEDTLNKLQEAEikvKELDVLQAKCNEQTKLIGSLTQQIRAS 735
Cdd:COG3206    182 EQLPELRKEL----EEAEAALEEFRQKNGLVDLS--EEAKLLLQQLSELE---SQLAEARAELAEAEARLAALRAQLGSG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  736 EEKLLDLAALQkansegklEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLdleknlSAVNQVKDSL 815
Cdd:COG3206    253 PDALPELLQSP--------VIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ------QEAQRILASL 318

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238  816 EKELQLLKEKftsaVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKE-REEREQQLTEAKV 890
Cdd:COG3206    319 EAELEALQAR----EASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEaRLAEALTVGNVRV 390
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 948-1193 1.70e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.44  E-value: 1.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  948 TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemITKHDADIKGFKQNLLDAEEALKAA 1027
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE--------LEALQAEIDKLQAEIAEAEAEIEER 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1028 QkknDELETQAEELKKQAEQAKSLSSVLASA--------RKEIELMSDKMRDLISEketLAQERNTLKLEKESLlsqhle 1099
Cdd:COG3883     85 R---EELGERARALYRSGGSVSYLDVLLGSEsfsdfldrLSALSKIADADADLLEE---LKADKAELEAKKAEL------ 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1100 meskillvQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRS 1179
Cdd:COG3883    153 --------EAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224

                          250
                   ....*....|....
gi 2024460238 1180 SESTLLQQLKELQA 1193
Cdd:COG3883    225 AAAAAAAAAAAAAA 238
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 770-1457 1.86e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.22  E-value: 1.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  770 IQNLETEKVGGSSKVSNLTKE--LQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKL 847
Cdd:pfam12128  148 IQNDRTLLGRERVELRSLARQfaLCDSESPLRHIDKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEHWI 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  848 NQKEEQFALMSSELEQLKsnltvMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ- 926
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTK-----LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEk 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  927 ---IQLELTKANEKAVQLQKNVEQTAQKAEQSQQ---ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETS 1000
Cdd:pfam12128  303 rdeLNGELSAADAAVAKDRSELEALEDQHGAFLDadiETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRS 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1001 EMITKHDADIKGFKQNLLDA-EEALKAAQKKNDELETQAEELKKQAEQAKSLSSV----LASARKEIELMSDKMRDLISE 1075
Cdd:pfam12128  383 KIKEQNNRDIAGIKDKLAKIrEARDRQLAVAEDDLQALESELREQLEAGKLEFNEeeyrLKSRLGELKLRLNQATATPEL 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1076 KETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALIS---- 1151
Cdd:pfam12128  463 LLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHflrk 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1152 -------EKSKLLSEIETAQADLlkITQENDALRSSESTLL------------------QQLK-ELQANKDAVDVACQKH 1205
Cdd:pfam12128  543 eapdweqSIGKVISPELLHRTDL--DPEVWDGSVGGELNLYgvkldlkridvpewaaseEELReRLDKAEEALQSAREKQ 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1206 IKEREELEHYQKLLEENDRvikDKDDVIQRLQSSYDDLAR----NQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNE 1281
Cdd:pfam12128  621 AAAEEQLVQANGELEKASR---EETFARTALKNARLDLRRlfdeKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKK 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1282 IDCLLQTNR--SLQSEKEMLLKSRE---ELCVSLA----NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASL 1352
Cdd:pfam12128  698 HQAWLEEQKeqKREARTEKQAYWQVvegALDAQLAllkaAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREI 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1353 SSLSNFLEEMKSSREASNSEKIhLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAvlaetafteKINELNLEKE 1432
Cdd:pfam12128  778 RTLERKIERIAVRRQEVLRYFD-WYQETWLQRRPRLATQLSNIERAISELQQQLARLIADT---------KLRRAKLEME 847

                          730       740
                   ....*....|....*....|....*
gi 2024460238 1433 SVFSKSLQFEKhNEALLREKDELER 1457
Cdd:pfam12128  848 RKASEKQQVRL-SENLRGLRCEMSK 871
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
357-505 2.01e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.86  E-value: 2.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  357 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAAD 422
Cdd:COG2433    347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  423 REKVELLNQLEEEKRKVEDLQFRVEEESItkgdlERKRQISEDPEnvaTVSEKSRIMELERDLALRVKEVAELRGRLESS 502
Cdd:COG2433    427 AEVEELEAELEEKDERIERLERELSEARS-----EERREIRKDRE---ISRLDREIERLERELEEERERIEELKRKLERL 498


                   ...
gi 2024460238  503 KHI 505
Cdd:COG2433    499 KEL 501
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1962-2092 2.17e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.86  E-value: 2.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1962 KEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASaktlqsvvktLESDKLKLEEKVKNLEQKLK-AKSEQ 2040
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEE----------LEAELEEKDERIERLERELSeARSEE 457

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024460238 2041 PltvtspsgdiaANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRM 2092
Cdd:COG2433    458 R-----------REIRKDREISRLDREIERLERELEEERERIEELKRKLERL 498
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1526-2040 2.41e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 49.72  E-value: 2.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1526 SDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKEN---LTVEKKARVLD 1602
Cdd:pfam05483  281 DENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAhsfVVTEFEATTCS 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1603 KESFL-LERMELQNNIGFLEKEVEEMREKNKEfLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1681
Cdd:pfam05483  361 LEELLrTEQQRLEKNEDQLKIITMELQKKSSE-LEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQ 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1682 SLS----VSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQE---NESLHAEWKSLVIINEEILKEKEKLSKEYYKLH 1754
Cdd:pfam05483  440 ELIfllqAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEklkNIELTAHCDKLLLENKELTQEASDMTLELKKHQ 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1755 EKVVALLEQTDAdfscrllvsegkhellleemsnlalKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDaihqe 1834
Cdd:pfam05483  520 EDIINCKKQEER-------------------------MLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLD----- 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1835 KIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELtkskellnlENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1914
Cdd:pfam05483  570 KSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN---------KNKNIEELHQENKALKKKGSAENKQLNAYEIKVNK 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1915 LAEELGRSRDE----VTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEErasLQKSISDTSALITQKDEELE 1990
Cdd:pfam05483  641 LELELASAKQKfeeiIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKR---CQHKIAEMVALMEKHKHQYD 717

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1991 KLRNEITVLRGENASAKTLQSVVK-TLESDKLKLEEKVKNLEQKLKAKSEQ 2040
Cdd:pfam05483  718 KIIEERDSELGLYKNKEQEQSSAKaALEIELSNIKAELLSLKKQLEIEKEE 768
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 641-889 3.42e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  641 SNLKLKQENEKSQHLKEIEALKAKLlevtEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQeaeikvKELDVLQAKCNE 720
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERR-IAALARRIRALE------QELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  721 QTKLIGSLTQQIRASEEKLLD-LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggSSKVSNLTKELQGKEQKLL 799
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAElLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYL----APARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  800 DLEKNLSAVNQVKDSLEKELQLLKEKFtsavdgaENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 879
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAAL-------EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

                          250
                   ....*....|
gi 2024460238  880 EREQQLTEAK 889
Cdd:COG4942    237 AAAAERTPAA 246
PRK01156 PRK01156
chromosome segregation protein; Provisional
 473-1075 3.88e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 49.13  E-value: 3.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  473 SEKSRIMELERDLALRVKEVAELrgrlesSKHIDDVDTSLS-LLQEISSLQEKMAAAGKEHQ------REMSSLKEKFES 545
Cdd:PRK01156   180 AEISNIDYLEEKLKSSNLELENI------KKQIADDEKSHSiTLKEIERLSIEYNNAMDDYNnlksalNELSSLEDMKNR 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  546 SEEALRKEIKTLSASNERMGK----ENESLKTKLDHANKENSDVIELWKSKleSAIASHQQAMEELKVSFNK--GVGAQT 619
Cdd:PRK01156   254 YESEIKTAESDLSMELEKNNYykelEERHMKIINDPVYKNRNYINDYFKYK--NDIENKKQILSNIDAEINKyhAIIKKL 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  620 AEFAELKTQMEKVKLDYE---NEMSNLKLKQENEKSqHLKEIEALKAKLlevtEEKEQTLENLKAKLESVEDQHLVEmed 696
Cdd:PRK01156   332 SVLQKDYNDYIKKKSRYDdlnNQILELEGYEMDYNS-YLKSIESLKKKI----EEYSKNIERMSAFISEILKIQEID--- 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  697 tlnklqeAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAA-LQKANSEGKLEIQKLSEQLQAAEKQIQNLET 775
Cdd:PRK01156   404 -------PDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRnMEMLNGQSVCPVCGTTLGEEKSNHIINHYNE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  776 EKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVK-DSLEKELQLLKEKFTSAVDgAENAQRAMQETINKLNQKEEQF 854
Cdd:PRK01156   477 KKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLED-IKIKINELKDKHDKYEEIKNRY 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  855 AlmSSELEQLKSNLTV------------METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKER 922
Cdd:PRK01156   556 K--SLKLEDLDSKRTSwlnalavislidIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNN 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  923 QLEQIQlELTKANEKavqLQKNVEQtaqkaeqsqqetLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM 1002
Cdd:PRK01156   634 KYNEIQ-ENKILIEK---LRGKIDN------------YKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANR 697

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238 1003 ITKhDADIKGFKQNLLDAEEALKAAQKKNDELET--QAEELKKQAEQAKSLSSVLASARKEI-ELMSDKMRDLISE 1075
Cdd:PRK01156   698 ARL-ESTIEILRTRINELSDRINDINETLESMKKikKAIGDLKRLREAFDKSGVPAMIRKSAsQAMTSLTRKYLFE 772
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
761-1063 4.88e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 4.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  761 EQLQAAEKQIQNLETEkvggsskVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLlkekftsavdgaenaqRAM 840
Cdd:COG4913    610 AKLAALEAELAELEEE-------LAEAEERLEALEAELDALQERREALQRLAEYSWDEIDV----------------ASA 666

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  841 QETINKLNQKEEQFALMSSELEQLKSnltvmetKLKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmndelrlk 920
Cdd:COG4913    667 EREIAELEAELERLDASSDDLAALEE-------QLEELEAELEELEEELDELKGEIGRL--------------------- 718

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  921 ERQLEQIQLELTkanekavQLQKNVEQTAQKAEQSQQETLKTHQEELKKmQDQLTDMKKQMETSQNQYKDLQAKYEKETS 1000
Cdd:COG4913    719 EKELEQAEEELD-------ELQDRLEAAEDLARLELRALLEERFAAALG-DAVERELRENLEERIDALRARLNRAEEELE 790

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024460238 1001 EMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQ---------AEELKKQAEQAKS-LSSVLASARKEIE 1063
Cdd:COG4913    791 RAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDglpeyeerfKELLNENSIEFVAdLLSKLRRAIREIK 863
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
671-1266 5.44e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 5.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  671 EKEQTLENLKAKLESVEDqhLVEMEDTLNKLQEaeiKVKELDVLQAKCNEQTKLIGSLTQQIRasEEKLLDLAALQKANS 750
Cdd:COG4913    219 EEPDTFEAADALVEHFDD--LERAHEALEDARE---QIELLEPIRELAERYAAARERLAELEY--LRAALRLWFAQRRLE 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  751 EGKLEIQKLSEQLQAAEKQIQNLETEKVG---------------GSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSL 815
Cdd:COG4913    292 LLEAELEELRAELARLEAELERLEARLDAlreeldeleaqirgnGGDRLEQLEREIERLERELEERERRRARLEALLAAL 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  816 -------EKELQLLKEKFTSAVDGAENAQRAMQ----ETINKLNQKEEQFALMSSELEQL---KSNLTVMETKLKEREER 881
Cdd:COG4913    372 glplpasAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLerrKSNIPARLLALRDALAE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  882 EQQLTEAKVKLendIAEIMKSSGDSS------------------------AQLMKMNDELRLKERqleqIQLELTKANEK 937
Cdd:COG4913    452 ALGLDEAELPF---VGELIEVRPEEErwrgaiervlggfaltllvppehyAAALRWVNRLHLRGR----LVYERVRTGLP 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  938 AVQLQKNVEQT-AQKAEqsqqetLKTH------QEELKKM--------QDQLTDMKKQMeTSQNQYKDLQAKYEKETSEM 1002
Cdd:COG4913    525 DPERPRLDPDSlAGKLD------FKPHpfrawlEAELGRRfdyvcvdsPEELRRHPRAI-TRAGQVKGNGTRHEKDDRRR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1003 ITKH-------DADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSV------LASARKEIELMSDKM 1069
Cdd:COG4913    598 IRSRyvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAEL 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1070 RDLISEKETLAQerntLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTekvAL 1149
Cdd:COG4913    678 ERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR---AL 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1150 ISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL-KELQANKDAVDVACQKHIKEREELEHYQKLLE--ENDRVI 1226
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEERIDALRARLNRAEEELeRAMRAFNREWPAETADLDADLESLPEYLALLDrlEEDGLP 830

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 2024460238 1227 KDKDDVIQRLQSSyddlarNQRELLQEVSILTAERDSAQE 1266
Cdd:COG4913    831 EYEERFKELLNEN------SIEFVADLLSKLRRAIREIKE 864
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1032-1589 5.82e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.36  E-value: 5.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1032 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1111
Cdd:PRK01156   176 DMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYE 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1112 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVA---LISEKSKLLSEIEtaqaDLLKITQENDALRSSESTLLQQL 1188
Cdd:PRK01156   256 SEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKnrnYINDYFKYKNDIE----NKKQILSNIDAEINKYHAIIKKL 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1189 KELQANKDAVdvacQKHIKEREELEH-----------YQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSIL 1257
Cdd:PRK01156   332 SVLQKDYNDY----IKKKSRYDDLNNqilelegyemdYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1258 TAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLlkSREELCVSLANTANENQALKLRKD--EMQTELETER 1335
Cdd:PRK01156   408 KKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEML--NGQSVCPVCGTTLGEEKSNHIINHynEKKSRLEEKI 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1336 EKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQealfaseqrllAEREELVNENKAVTEKLTKATAdavL 1415
Cdd:PRK01156   486 REIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESAR-----------ADLEDIKIKINELKDKHDKYEE---I 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1416 AETAFTEKINELNLEKESVFSKSLQFEKHN-EALLREKDELERKYSELLDEKKSLENAFSDMKRE-----QELDFSAKRL 1489
Cdd:PRK01156   552 KNRYKSLKLEDLDSKRTSWLNALAVISLIDiETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYidksiREIENEANNL 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1490 LVQENttLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNR 1569
Cdd:PRK01156   632 NNKYN--EIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRT 709

                          570       580
                   ....*....|....*....|
gi 2024460238 1570 ERTELQDKCQKLTGEVENMK 1589
Cdd:PRK01156   710 RINELSDRINDINETLESMK 729
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 802-1058 6.64e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.52  E-value: 6.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  802 EKNLSAVNQVKDSLEKELQLLKEKftsavdgAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREER 881
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAE-------LDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  882 -EQQLTEAKVK-LENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQlELTKANEKAVQLQKNVEQTAQKAEQSQQEt 959
Cdd:COG3883     88 lGERARALYRSgGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLE-ELKADKAELEAKKAELEAKLAELEALKAE- 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  960 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAE 1039
Cdd:COG3883    166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAS 245

                          250
                   ....*....|....*....
gi 2024460238 1040 ELKKQAEQAKSLSSVLASA 1058
Cdd:COG3883    246 AAGAGAAGAAGAAAGSAGA 264
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 617-855 7.34e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  617 AQTAEFAELKTQMEKVKldyenemsnlklKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQhLVEMED 696
Cdd:COG4942     17 AQADAAAEAEAELEQLQ------------QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE-LAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  697 TLNKLQeaeikvKELDVLQAKCNEQTKLIGSLTQQI----RASEEKLL-----------DLAALQKANSEGKLEIQKLSE 761
Cdd:COG4942     84 ELAELE------KEIAELRAELEAQKEELAELLRALyrlgRQPPLALLlspedfldavrRLQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  762 QLQAAEKQIQNLETEKvggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEkftsAVDGAENAQRAMQ 841
Cdd:COG4942    158 DLAELAALRAELEAER-------AELEALLAELEEERAALEALKAERQKLLARLEKELAELAA----ELAELQQEAEELE 226

                          250
                   ....*....|....
gi 2024460238  842 ETINKLNQKEEQFA 855
Cdd:COG4942    227 ALIARLEAEAAAAA 240
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 530-686 7.48e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 47.71  E-value: 7.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  530 KEHQREMSSLKEKFE---SSEEALRKEIKTLSASNERM---GKENESLKTKLDHANKENSDVIELWK------SKLESAI 597
Cdd:pfam05667  331 QQREEELEELQEQLEdleSSIQELEKEIKKLESSIKQVeeeLEELKEQNEELEKQYKVKKKTLDLLPdaeeniAKLQALV 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  598 ASHQQAMEELKVSFNKGVGAQTAEFAELKTQmekvkldyenemsnlKLKQENEKSQHLKEIEALKAKLLEVTEE---KEQ 674
Cdd:pfam05667  411 DASAQRLVELAGQWEKHRVPLIEEYRALKEA---------------KSNKEDESQRKLEEIKELREKIKEVAEEakqKEE 475

                          170
                   ....*....|..
gi 2024460238  675 TLENLKAKLESV 686
Cdd:pfam05667  476 LYKQLVAEYERL 487
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 354-1427 7.52e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 48.12  E-value: 7.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  354 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV-GEIEQELALVRDGhdrhvlEMEAKMDQLRAMVEAADREKVEllnql 432
Cdd:TIGR01612  625 LKKIIENNNAYIDELAKISPYQVPEHLKNKDKIySTIKSELSKIYED------DIDALYNELSSIVKENAIDNTE----- 693

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  433 eeEKRKVEDLQFRVEEESITKGDLERKRQIS-----EDPEN--VATVSEKSRIM--ELERDLALRVKEVAELRGRLES-- 501
Cdd:TIGR01612  694 --DKAKLDDLKSKIDKEYDKIQNMETATVELhlsniENKKNelLDIIVEIKKHIhgEINKDLNKILEDFKNKEKELSNki 771

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  502 ---SKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMsslKEKFESSEEALR----KEIKTLSASNERMGKENESLKTK 574
Cdd:TIGR01612  772 ndyAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDA---KQNYDKSKEYIKtisiKEDEIFKIINEMKFMKDDFLNKV 848

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  575 LDHANKENSDvielwKSKLESAIASHQQAMEELKVSF-NKGVGAQTAEFAELKTQMEKVKLDYENEMSNLK-LKQENEks 652
Cdd:TIGR01612  849 DKFINFENNC-----KEKIDSEHEQFAELTNKIKAEIsDDKLNDYEKKFNDSKSLINEINKSIEEEYQNINtLKKVDE-- 921

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  653 qHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVE------MEDTL-NKLQEAEIKVKELDV--LQAKCNEQTK 723
Cdd:TIGR01612  922 -YIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEksykdkFDNTLiDKINELDKAFKDASLndYEAKNNELIK 1000

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  724 LIGSLTQQIRASEEKLldlaaLQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLD--- 800
Cdd:TIGR01612 1001 YFNDLKANLGKNKENM-----LYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIELLNkei 1075

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  801 ---LEKNLSAVNQVKDSLE--KELQLLKE---KFTSAV----DGAENAQRAMQETINKL----NQKEEQFALMSSELEQL 864
Cdd:TIGR01612 1076 leeAEINITNFNEIKEKLKhyNFDDFGKEeniKYADEInkikDDIKNLDQKIDHHIKALeeikKKSENYIDEIKAQINDL 1155

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  865 K--SNLTVMETKLKEREEREQQLT----------EAKVKLENDIAEIMKSSGD-SSAQLMKMNDELRLKERQLEQIQLEL 931
Cdd:TIGR01612 1156 EdvADKAISNDDPEEIEKKIENIVtkidkkkniyDEIKKLLNEIAEIEKDKTSlEEVKGINLSYGKNLGKLFLEKIDEEK 1235

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  932 TKANEKAVQLQKNVEQTAQKAEQSQqetlkthqeELKKMQDQLTDMKKQMET---SQNQYKD---LQAKYEKETSEMITK 1005
Cdd:TIGR01612 1236 KKSEHMIKAMEAYIEDLDEIKEKSP---------EIENEMGIEMDIKAEMETfniSHDDDKDhhiISKKHDENISDIREK 1306

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1006 HDADIKGF--KQNLLDAEEALKA----AQKKNDELETQAEELKK-----QAEQAKSLSSVLASARKEIELMSDKMRDLIS 1074
Cdd:TIGR01612 1307 SLKIIEDFseESDINDIKKELQKnlldAQKHNSDINLYLNEIANiynilKLNKIKKIIDEVKEYTKEIEENNKNIKDELD 1386

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1075 EKETLAQerntlKLEKESLLSqhlEMESKI--LLVQQDREELWTKNEELNSEnkkILKQKEAAEA--KSRQESTEKVALi 1150
Cdd:TIGR01612 1387 KSEKLIK-----KIKDDINLE---ECKSKIesTLDDKDIDECIKKIKELKNH---ILSEESNIDTyfKNADENNENVLL- 1454

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1151 sekskLLSEIETAQAD---LLKITQENdalrsSESTLLQQLKELQANKDavdvacqKHIKEREELEHYQKLLEENDRVIK 1227
Cdd:TIGR01612 1455 -----LFKNIEMADNKsqhILKIKKDN-----ATNDHDFNINELKEHID-------KSKGCKDEADKNAKAIEKNKELFE 1517

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1228 D-KDDVIQRLQSSYDDLARNQrellqevsILTAERDSAQEKDlDLKSthiaLKNEIdcLLQTNRSLQSEKEMllkSREEL 1306
Cdd:TIGR01612 1518 QyKKDVTELLNKYSALAIKNK--------FAKTKKDSEIIIK-EIKD----AHKKF--ILEAEKSEQKIKEI---KKEKF 1579

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1307 CVSlANTANENQALKLRKDeMQTELETEREKLEKMT----------KDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL 1376
Cdd:TIGR01612 1580 RIE-DDAAKNDKSNKAAID-IQLSLENFENKFLKISdikkkindclKETESIEKKISSFSIDSQDTELKENGDNLNSLQE 1657

                         1130      1140      1150      1160      1170
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1377 LQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINEL 1427
Cdd:TIGR01612 1658 FLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEI 1708
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 751-1144 7.66e-05

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 48.03  E-value: 7.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  751 EGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKE--QKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTS 828
Cdd:COG5185    189 LKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEalKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  829 AVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETK------LKEREEREQQLTEAKVKLENDIAEIMKS 902
Cdd:COG5185    269 KLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLeeqlaaAEAEQELEESKRETETGIQNLTAEIEQG 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  903 SGDSSAQLMKMNDE---------LRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQ 973
Cdd:COG5185    349 QESLTENLEAIKEEienivgeveLSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQ 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  974 LTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKgfkqnlldaeealKAAQKKNDELETQAEELKKQAEQAKS-LS 1052
Cdd:COG5185    429 IEQATSSNEEVSKLLNELISELNKVMREADEESQSRLE-------------EAYDEINRSVRSKKEDLNEELTQIESrVS 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1053 SVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1132
Cdd:COG5185    496 TLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTDGQAANLRTAVIDELTQ 575

                          410
                   ....*....|..
gi 2024460238 1133 EAAEAKSRQEST 1144
Cdd:COG5185    576 YLSTIESQQARE 587
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 714-1086 8.08e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 47.87  E-value: 8.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  714 LQAKCNEQTKLIGSlTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETekvggsskvSNLTKELQG 793
Cdd:PRK10246   225 LQVLTDEEKQLLTA-QQQQQQSLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAALSL---------AQPARQLRP 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  794 KEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQ---KEEQFALMSSELEQLKSNLTV 870
Cdd:PRK10246   295 HWERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSLNTwlaEHDRFRQWNNELAGWRAQFSQ 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  871 METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMkmndELRLKERQLEQiqlELTKANEKAVQLQKNVEQTaq 950
Cdd:PRK10246   375 QTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAAL----AQHAEQRPLRQ---RLVALHGQIVPQQKRLAQL-- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  951 kaeqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsEMItkhdADIKGFKQNL------------- 1017
Cdd:PRK10246   446 ------QVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQE--ARI----KDLEAQRAQLqagqpcplcgsts 513

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024460238 1018 ---LDAEEALK--AAQKKNDELEtqaEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL 1086
Cdd:PRK10246   514 hpaVEAYQALEpgVNQSRLDALE---KEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAV 584
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1019-1379 8.11e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.58  E-value: 8.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1019 DAEEALKAAQKKNDELETQAEELKKQAEQAKSlssVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1098
Cdd:pfam07888   56 QREKEKERYKRDREQWERQRRELESRVAELKE---ELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIR 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1099 EMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALR 1178
Cdd:pfam07888  133 ELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQ 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1179 SSESTLLQQLKELQANKDAVDVACqkhikerEELEHYQKLLEENDRVIKDKDDVIQRLQSSYDdlaRNQRELLQevsilt 1258
Cdd:pfam07888  213 DTITTLTQKLTTAHRKEAENEALL-------EELRSLQERLNASERKVEGLGEELSSMAAQRD---RTQAELHQ------ 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1259 aERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQS----EKEMLLKSREELcvslantanenqalkLRKDEMQTELETE 1334
Cdd:pfam07888  277 -ARLQAAQLTLQLADASLALREGRARWAQERETLQQsaeaDKDRIEKLSAEL---------------QRLEERLQEERME 340

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 2024460238 1335 REKLE-KMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQE 1379
Cdd:pfam07888  341 REKLEvELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1809-2007 8.58e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 8.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1809 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1888
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1889 KEFEALkLAAAQKSQQ----------------------LAALQEENVKLAEELGRSRDEVTS-HQKLEEERSVLNNQLLE 1945
Cdd:COG4942    104 EELAEL-LRALYRLGRqpplalllspedfldavrrlqyLKYLAPARREQAEELRADLAELAAlRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238 1946 MKKSLpsntLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAK 2007
Cdd:COG4942    183 LEEER----AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 863-1533 9.57e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.79  E-value: 9.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  863 QLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAE---IMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAV 939
Cdd:pfam05483  107 KLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQEnkdLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  940 QLQKNVEQTAQKAEQSQQETLKTHQEelkkMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLD 1019
Cdd:pfam05483  187 DLNNNIEKMILAFEELRVQAENARLE----MHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1020 AEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLE 1099
Cdd:pfam05483  263 LEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNK 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1100 MESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRS 1179
Cdd:pfam05483  343 AKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLD 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1180 SESTLLQQLKELQANKDAVDVACQKHIKEREELE-----------HYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQR 1248
Cdd:pfam05483  423 EKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEiqltaiktseeHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENK 502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1249 ELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSE----KEMLLKSREELCVSLANTANENQALKLRK 1324
Cdd:pfam05483  503 ELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesvREEFIQKGDEVKCKLDKSEENARSIEYEV 582

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1325 DEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSE------KIHLLQEALFASEQRLlaerEELVNE 1398
Cdd:pfam05483  583 LKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQlnayeiKVNKLELELASAKQKF----EEIIDN 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1399 NKAVTEkLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDelERKYSELLDEKKSLENAFSDMKR 1478
Cdd:pfam05483  659 YQKEIE-DKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKH--KHQYDKIIEERDSELGLYKNKEQ 735

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238 1479 EQEldfSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQ 1533
Cdd:pfam05483  736 EQS---SAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
46 PHA02562
endonuclease subunit; Provisional
 737-1042 1.08e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.32  E-value: 1.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  737 EKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETekvggsskvsnltkelQGKEQKllDLEKNLSAVNQVkdsle 816
Cdd:PHA02562   157 EDLLDISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQ----------------QIKTYN--KNIEEQRKKNGE----- 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  817 kELQLLKEKFTSAVDGAENAqramqetinklnqkeeqfalmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDI 896
Cdd:PHA02562   214 -NIARKQNKYDELVEEAKTI---------------------KAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKI 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  897 AEIMKssgdssaqLMKM---NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQ 971
Cdd:PHA02562   272 EQFQK--------VIKMyekGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKldTAIDELEEIMDEFNEQSKKLLELK 343

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024460238  972 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITkHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1042
Cdd:PHA02562   344 NKISTNKQSLITLVDKAKKVKAAIEELQAEFVD-NAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLK 413
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 755-1059 1.09e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  755 EIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGkeqklldLEKNLSAVNQVKD-SLEKELQLLKEKftsaVDGA 833
Cdd:COG3096    837 ELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQL-------LNKLLPQANLLADeTLADRLEELREE----LDAA 905

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  834 ENAQRAMQETINKLNQKEEQFALMSSELEQLKsNLTVMETKLKEREEREQQLTEAkvklendIAEIMK-----SSGDSSA 908
Cdd:COG3096    906 QEAQAFIQQHGKALAQLEPLVAVLQSDPEQFE-QLQADYLQAKEQQRRLKQQIFA-------LSEVVQrrphfSYEDAVG 977

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  909 QLMK---MNDELRlkeRQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ 985
Cdd:COG3096    978 LLGEnsdLNEKLR---ARLEQAEEARREAREQLRQAQAQYSQ-YNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEA 1053

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238  986 NQykdlQAKYEK-ETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK-SLSSVLASAR 1059
Cdd:COG3096   1054 EE----RARIRRdELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKaGWCAVLRLAR 1125
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 872-1063 1.12e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  872 ETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK 951
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  952 AEQSQQ--------------ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMitkhdadikgfKQNL 1017
Cdd:COG3883     95 LYRSGGsvsyldvllgsesfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAEL-----------EALK 163

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2024460238 1018 LDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIE 1063
Cdd:COG3883    164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAE 209
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 830-1193 1.13e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  830 VDGAENAQRAMQETINKLNQKEEQFALMSSELEQLksnltvmetklkerEEREQQLTEakvklENDIAeimkssgdsSAQ 909
Cdd:COG3096    284 SERALELRRELFGARRQLAEEQYRLVEMARELEEL--------------SARESDLEQ-----DYQAA---------SDH 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  910 LMKMNDELRLKERqLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQN--- 986
Cdd:COG3096    336 LNLVQTALRQQEK-IERYQEDLEELTERLEEQEEVVEE-AAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTrai 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  987 QYKD-LQAKYEKE--------TSEMITKHDADIK-----------GFKQNLLDA-------EEALKAAQKKNDELET--- 1036
Cdd:COG3096    414 QYQQaVQALEKARalcglpdlTPENAEDYLAAFRakeqqateevlELEQKLSVAdaarrqfEKAYELVCKIAGEVERsqa 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1037 ---------QAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDL----------ISEKETLAQERNTLKLEKESLLSQH 1097
Cdd:COG3096    494 wqtarellrRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLeefcqrigqqLDAAEELEELLAELEAQLEELEEQA 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1098 LEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEaKSRQESTEKVAlisEKSKLLSEIETAQADLLKITQENDAL 1177
Cdd:COG3096    574 AEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALE-RLREQSGEALA---DSQEVTAAMQQLLEREREATVERDEL 649

                          410
                   ....*....|....*.
gi 2024460238 1178 RSSESTLLQQLKELQA 1193
Cdd:COG3096    650 AARKQALESQIERLSQ 665
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1107-1537 1.15e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1107 VQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSES--TL 1184
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1185 LQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQ-RELLQEVSILTAERDS 1263
Cdd:COG4717    131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAE 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1264 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQ-----SEKEMLLKSREELCVSLANTAN----------------------- 1315
Cdd:COG4717    211 LEEELEEAQEELEELEEELEQLENELEAAAleerlKEARLLLLIAAALLALLGLGGSllsliltiagvlflvlgllallf 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1316 ---ENQALKLRKDEMQTELETEREKLEK------MTKDNMDLKASLSSLSNFLEEMKSSREAsNSEKIHLLQEALfasEQ 1386
Cdd:COG4717    291 lllAREKASLGKEAEELQALPALEELEEeeleelLAALGLPPDLSPEELLELLDRIEELQEL-LREAEELEEELQ---LE 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1387 RLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQF-EKHNEALLREK--------DELER 1457
Cdd:COG4717    367 ELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELlEALDEEELEEEleeleeelEELEE 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1458 KYSELLDEKKSLENAFSDMKREQELDfsakrllvqentTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARR 1537
Cdd:COG4717    447 ELEELREELAELEAELEQLEEDGELA------------ELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
PTZ00121 PTZ00121
MAEBL; Provisional
 1027-1885 1.16e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1027 AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKIll 1106
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKA-- 1160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1107 vqqdreelwtkneelnSENKKILKQKEAAEAKSRQESTEkvaliSEKSKLLSEIETAQadllKITQENDALRSSESTLLQ 1186
Cdd:PTZ00121  1161 ----------------EDARKAEEARKAEDAKKAEAARK-----AEEVRKAEELRKAE----DARKAEAARKAEEERKAE 1215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1187 QLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQE 1266
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEA 1295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1267 KDLDLKSTHIALKNEIDCLLQTNRsLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNM 1346
Cdd:PTZ00121  1296 KKAEEKKKADEAKKKAEEAKKADE-AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1347 DLKASLSSLSNFLEEMKSSREASN--SEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAftEKI 1424
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKADEAKKkaEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA--KKK 1452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1425 NELNLEKESVFSKSLQFEKHNEAllREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEAL 1504
Cdd:PTZ00121  1453 AEEAKKAEEAKKKAEEAKKADEA--KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1505 EEELKKKNLENQEliacRSDLSDLLKEAQDARRTLENELAavsHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGE 1584
Cdd:PTZ00121  1531 EEAKKADEAKKAE----EKKKADELKKAEELKKAEEKKKA---EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEE 1603

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1585 VENMK-ENLTVEKKARVldKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILY 1663
Cdd:PTZ00121  1604 EKKMKaEEAKKAEEAKI--KAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK 1681

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1664 KETEQLASKIEQLKSDFTSL----SVSKAELEDVHSCVSVMLDELQHKYEVTE--KEKMELVQENESLHAEWKSLVIInE 1737
Cdd:PTZ00121  1682 KAEEDEKKAAEALKKEAEEAkkaeELKKKEAEEKKKAEELKKAEEENKIKAEEakKEAEEDKKKAEEAKKDEEEKKKI-A 1760

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1738 EILKEKEKLSKEYYKLHEKVVAllEQTDADFSCRLLVSEGKHElllEEMSNLALKLREIERLQAQTFMQKFEADKRAEEV 1817
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIE--EELDEEDEKRRMEVDKKIK---DIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEV 1835

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238 1818 LQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQnnlkNEEELTKSKELLNLENKKVE 1885
Cdd:PTZ00121  1836 ADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKED----DEEEIEEADEIEKIDKDDIE 1899
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1501-2037 1.31e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.20  E-value: 1.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1501 IEALEEELKKKNLE----NQELIACRSDLSDLLKEAQDarrtLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQD 1576
Cdd:PRK01156   185 IDYLEEKLKSSNLEleniKKQIADDEKSHSITLKEIER----LSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKT 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1577 KCQKLTGEVENMKENLTVEKkarvldkesfllERMELQNNigflekEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVI 1656
Cdd:PRK01156   261 AESDLSMELEKNNYYKELEE------------RHMKIIND------PVYKNRNYINDYFKYKNDIENKKQILSNIDAEIN 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1657 KEKMILYK--ETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVI 1734
Cdd:PRK01156   323 KYHAIIKKlsVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEI 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1735 INEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHEL------------LLEEMSNLALKL--REIERLQ 1800
Cdd:PRK01156   403 DPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgttLGEEKSNHIINHynEKKSRLE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1801 AQTFMQKFEADKRAEEVLQtmekVTKEKDAIHQEKIETLAS----LENSRQTNEKLQNELDMLKQNNLKNEE--ELTKSK 1874
Cdd:PRK01156   483 EKIREIEIEVKDIDEKIVD----LKKRKEYLESEEINKSINeynkIESARADLEDIKIKINELKDKHDKYEEikNRYKSL 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1875 ELLNLENKKVEELKK-------EFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEM 1946
Cdd:PRK01156   559 KLEDLDSKRTSWLNAlavisliDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSiREIENEANNLNNKYNEI 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1947 K-KSLPSNTLREST--LKKEIdEERASLQKSISDTSALITQKDEELEKLRNEitvLRGENASAKTLQSVVKTLESDKLKL 2023
Cdd:PRK01156   639 QeNKILIEKLRGKIdnYKKQI-AEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKANRARLESTIEILRTRINEL 714

                          570
                   ....*....|....
gi 2024460238 2024 EEKVKNLEQKLKAK 2037
Cdd:PRK01156   715 SDRINDINETLESM 728
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1789-1995 1.70e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1789 LALKLREIERLQAQtfmqKFEADKRAEEVLQTMEKVTKEKDAIHQekietLASLENSRQTNEKLQNELdmlkqnnlkneE 1868
Cdd:COG4913    612 LAALEAELAELEEE----LAEAEERLEALEAELDALQERREALQR-----LAEYSWDEIDVASAEREI-----------A 671

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1869 ELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEmkk 1948
Cdd:COG4913    672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--- 748

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2024460238 1949 SLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNE 1995
Cdd:COG4913    749 ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1830-2040 1.73e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1830 AIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQ 1909
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1910 EENVKLAEELGRSRDEVTSHQKLEEERSVLNNQllemkksLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEEL 1989
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1990 EKLRNEITVLRGENASAKtlqsvvKTLESDKLKLEEKVKNLEQKLKAKSEQ 2040
Cdd:COG4942    170 EAERAELEALLAELEEER------AALEALKAERQKLLARLEKELAELAAE 214
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
353-993 1.74e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 1.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrHVLEMEAKMDQLRAMVEAADREKVELLNQL 432
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE--------ELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  433 EEEKRKVEDLQfrvEEESITKGDLERKrqiSEDPENVATVSE--KSRIMELERDLALRVKEVAELRGRLES-SKHIDDVD 509
Cdd:PRK02224   282 RDLRERLEELE---EERDDLLAEAGLD---DADAEAVEARREelEDRDEELRDRLEECRVAAQAHNEEAESlREDADDLE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  510 TslsllqEISSLQEKMAAAGKEHQREMSSLkEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELW 589
Cdd:PRK02224   356 E------RAEELREEAAELESELEEAREAV-EDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  590 KSkLESAIASHQQAMEELKVSFNKGVGAQTAefaelktqmekvkldyenemsnlklkQENEKSQHLKEIEALKAKLLEVT 669
Cdd:PRK02224   429 AE-LEATLRTARERVEEAEALLEAGKCPECG--------------------------QPVEGSPHVETIEEDRERVEELE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  670 EEkeqtLENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDvlqakcnEQTKLIGSLTQQIRASeeklldlaalqkan 749
Cdd:PRK02224   482 AE----LEDLEEEVEEVEERL-----ERAEDLVEAEDRIERLE-------ERREDLEELIAERRET-------------- 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  750 segkleIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEkftsa 829
Cdd:PRK02224   532 ------IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAA----- 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  830 vdgAENAqramQETINKLNQKEEQFALMSSELEQlksnltvmetKLKEREEREQQLTEakvKLENDIAEIMKSSGDSSaq 909
Cdd:PRK02224   601 ---IADA----EDEIERLREKREALAELNDERRE----------RLAEKRERKRELEA---EFDEARIEEAREDKERA-- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  910 lmkmndelrlkERQLEQIQLELTKANEKAVQLQKNVeqTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYK 989
Cdd:PRK02224   659 -----------EEYLEQVEEKLDELREERDDLQAEI--GAVENELEELEELRERREALENRVEALEALYDEAEELESMYG 725


                   ....
gi 2024460238  990 DLQA 993
Cdd:PRK02224   726 DLRA 729
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1119-1395 1.93e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 1.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1119 EELNSENKKILKQKEAAEAKSRQESTEKVALI--SEKSKLLSEIETAQA--DLLKITQENDALRSSESTLLQQLKELQAN 1194
Cdd:PLN02939   106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIqnAEKNILLLNQARLQAleDLEKILTEKEALQGKINILEMRLSETDAR 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1195 kdaVDVACQKHIKEREELEHYQKLLEEndrvikdkddVIQRLQSSYddlarnqrellQEVSILTAERDSAQEKDLDLKST 1274
Cdd:PLN02939   186 ---IKLAAQEKIHVEILEEQLEKLRNE----------LLIRGATEG-----------LCVHSLSKELDVLKEENMLLKDD 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1275 HIALKNEIDCLLQTNRS---LQSEKEMLLKSREEL-CVSLANTANENQALKLRKDEMQTELETEREKLEKMTK------- 1343
Cdd:PLN02939   242 IQFLKAELIEVAETEERvfkLEKERSLLDASLRELeSKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATNqvekaal 321

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238 1344 ---DNMDLKASLSSLSNFLEEMKSSREASnsEKIHLLQEALFASEQRLLAEREEL 1395
Cdd:PLN02939   322 vldQNQDLRDKVDKLEASLKEANVSKFSS--YKVELLQQKLKLLEERLQASDHEI 374
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1557-2090 1.93e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 1.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1557 FNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARVLDKESFLLERMELQNnigfLEKEVEEMREKNKEFLT 1636
Cdd:TIGR04523   70 INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNK----LEKQKKENKKNIDKFLT 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1637 EKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHScvsvMLDELQHKYEVTEKEKM 1716
Cdd:TIGR04523  146 EIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS----NLKKKIQKNKSLESQIS 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1717 ELVQENESLHAEWKSLviiNEEILKEKEKLSKEYYKL------HEKVVALLEQTDADfscrLLVSEGKHELLLEEMSNLA 1790
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKK---QQEINEKTTEISNTQTQLnqlkdeQNKIKKQLSEKQKE----LEQNNKKIKELEKQLNQLK 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1791 LKLREIERLQAQTFMQKF--EADKRAEEVLQTMEKVTKEKDAIHQ--EKIETL-ASLENSRQTNEKLQNELDMlKQNNLK 1865
Cdd:TIGR04523  295 SEISDLNNQKEQDWNKELksELKNQEKKLEEIQNQISQNNKIISQlnEQISQLkKELTNSESENSEKQRELEE-KQNEIE 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1866 --NEEELTKSKELLNLENKKvEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK----LEEERSVL 1939
Cdd:TIGR04523  374 klKKENQSYKQEIKNLESQI-NDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSeikdLTNQDSVK 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1940 NNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKsisdTSALITQKDEELEKLRNEITVLRGEnasaktlqsvVKTLESD 2019
Cdd:TIGR04523  453 ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ----KQKELKSKEKELKKLNEEKKELEEK----------VKDLTKK 518

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024460238 2020 KLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQD---ESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQ 2090
Cdd:TIGR04523  519 ISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEnleKEIDEKNKEIEELKQTQKSLKKKQEEKQELID 592
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 966-1201 2.03e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 2.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  966 ELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkhdadikgfkqnLLDAEEALKAAQKKNDELETQAEELKKQA 1045
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEE---------------YNELQAELEALQAEIDKLQAEIAEAEAEI 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1046 EQAKS-LSSVLASARK--------EIELMSDKMRDLISEKETLAQerntlklekesllsqhlemeskilLVQQDREELwt 1116
Cdd:COG3883     82 EERREeLGERARALYRsggsvsylDVLLGSESFSDFLDRLSALSK------------------------IADADADLL-- 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1117 knEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKD 1196
Cdd:COG3883    136 --EELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAA 213


                   ....*
gi 2024460238 1197 AVDVA 1201
Cdd:COG3883    214 AAAAA 218
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
620-1138 2.25e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  620 AEFAELKTQMEKVKlDYENEMSNLKLKQEneksqHLKEIEALKAKLLEVTEEKEQtLENLKAKLESVEDQhlvemedtln 699
Cdd:COG4913    225 EAADALVEHFDDLE-RAHEALEDAREQIE-----LLEPIRELAERYAAARERLAE-LEYLRAALRLWFAQ---------- 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  700 klQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAlQKANSEGkleiqklsEQLQAAEKQIQNLETEKVG 779
Cdd:COG4913    288 --RRLELLEAELEELRAELARLEAELERLEARLDALREELDELEA-QIRGNGG--------DRLEQLEREIERLERELEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  780 GSSKVSNLTKELQGKEQKLL----DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFA 855
Cdd:COG4913    357 RERRRARLEALLAALGLPLPasaeEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  856 LMSSELEQ----LKSNLTVMETKLK-------------------ER------------EEREQQLTEA------------ 888
Cdd:COG4913    437 NIPARLLAlrdaLAEALGLDEAELPfvgelievrpeeerwrgaiERvlggfaltllvpPEHYAAALRWvnrlhlrgrlvy 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  889 -KVKLENDIAEIMKSSGDSSAQLMK---------MNDELRLK--------ERQLEQ----IQLE-LTKANEKAVQLQKnv 945
Cdd:COG4913    517 eRVRTGLPDPERPRLDPDSLAGKLDfkphpfrawLEAELGRRfdyvcvdsPEELRRhpraITRAgQVKGNGTRHEKDD-- 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  946 eQTAQKAE----QSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeKETSEMITKH---DADIKGFKQNLL 1018
Cdd:COG4913    595 -RRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQER--REALQRLAEYswdEIDVASAEREIA 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1019 DAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1098
Cdd:COG4913    672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 2024460238 1099 EMESKILLVQQDREELWtknEELNSENKKILKQKEAAEAK 1138
Cdd:COG4913    752 EERFAAALGDAVERELR---ENLEERIDALRARLNRAEEE 788
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1426-1857 2.26e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.71  E-value: 2.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1426 ELNLEKESVFSKSLQFEK-HNEALLREKDE----LERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYS 1500
Cdd:pfam01576  109 EEQLDEEEAARQKLQLEKvTTEAKIKKLEEdillLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAM 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1501 IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQK 1580
Cdd:pfam01576  189 ISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRE 268

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1581 LTGEVENMKENLTVEKKARVLDK-------ESFLLERMELQNNIGFL----------EKEVEEMREKNKEFLTEKELLVQ 1643
Cdd:pfam01576  269 LEAQISELQEDLESERAARNKAEkqrrdlgEELEALKTELEDTLDTTaaqqelrskrEQEVTELKKALEEETRSHEAQLQ 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1644 EKEKSET--------KLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK 1715
Cdd:pfam01576  349 EMRQKHTqaleelteQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1716 MELVQENESLHAEWKSLVIINEEILKEKEKLSKEY----YKLHEKVVALLEQTDA--DFSCRLLVSEGKHELLLEEMSNL 1789
Cdd:pfam01576  429 AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVssleSQLQDTQELLQEETRQklNLSTRLRQLEDERNSLQEQLEEE 508

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024460238 1790 ALKLREIERLQAQTFMQKFEADKRAEEVLQTME-------KVTKEKDAIHQEKIETLASLENSRQTNEKLQNELD 1857
Cdd:pfam01576  509 EEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEaleegkkRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELD 583
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
851-1543 2.59e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  851 EEQFALMSSELEQLKSnltvMETKLKEREEREQQLTEAKvklenDIAEIMKSSGDSSAQLMKMNDELRL--KERQLEQIQ 928
Cdd:COG4913    224 FEAADALVEHFDDLER----AHEALEDAREQIELLEPIR-----ELAERYAAARERLAELEYLRAALRLwfAQRRLELLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  929 LELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQ---AKYEKETSEMITK 1005
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERErrrARLEALLAALGLP 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1006 HDADIKGFKQN-------LLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKet 1078
Cdd:COG4913    375 LPASAEEFAALraeaaalLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA-- 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1079 laqerntLKLEKESL--LSQHLEMESK-----------------ILLVQQDREELWTknEELNSENKKILKQKEAAEAKS 1139
Cdd:COG4913    453 -------LGLDEAELpfVGELIEVRPEeerwrgaiervlggfalTLLVPPEHYAAAL--RWVNRLHLRGRLVYERVRTGL 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1140 RQESTEKvalISEKS---KLLSEIETAQADLLKITQENDALRSSESTllqqlKELQANKDAVDVACQ-KHIKEREELEHY 1215
Cdd:COG4913    524 PDPERPR---LDPDSlagKLDFKPHPFRAWLEAELGRRFDYVCVDSP-----EELRRHPRAITRAGQvKGNGTRHEKDDR 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1216 QKLLEE------NDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQ------EKDLDLKSTHIALkneid 1283
Cdd:COG4913    596 RRIRSRyvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeysWDEIDVASAEREI----- 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1284 cllqtnRSLQSEKEMLLKSREELcvslantanenQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMK 1363
Cdd:COG4913    671 ------AELEAELERLDASSDDL-----------AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1364 SSREASNSEKIHLLQEALfasEQRLLAE---------REELVNENKAVTEKLTKATADAVLAETAFTEK----INELNLE 1430
Cdd:COG4913    734 DRLEAAEDLARLELRALL---EERFAAAlgdaverelRENLEERIDALRARLNRAEEELERAMRAFNREwpaeTADLDAD 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1431 KESVFskslQFEKHNEALlrEKDELERKYSELLDEKKSLENAF-----SDMKREQEldfSAKRLLVQENTTLK------- 1498
Cdd:COG4913    811 LESLP----EYLALLDRL--EEDGLPEYEERFKELLNENSIEFvadllSKLRRAIR---EIKERIDPLNDSLKripfgpg 881

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 2024460238 1499 --YSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENEL 1543
Cdd:COG4913    882 ryLRLEARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 742-902 3.05e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 3.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  742 LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKD--SLEKEL 819
Cdd:COG1579     19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeALQKEI 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  820 QLLKEKftsavdgAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLtvmETKLKEREEREQQLTEAKVKLENDIAEI 899
Cdd:COG1579     99 ESLKRR-------ISDLEDEILELMERIEELEEELAELEAELAELEAEL---EEKKAELDEELAELEAELEELEAEREEL 168


                   ...
gi 2024460238  900 MKS 902
Cdd:COG1579    169 AAK 171
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1783-2001 3.54e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 3.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1783 LEEMSNLALKLRE-IERLQaqtfmqkfeadkRAEEVLQTMEKVTKEKDaiHQEKIETLASLENSRQTNEKLQNELDmlkq 1861
Cdd:COG4913    237 LERAHEALEDAREqIELLE------------PIRELAERYAAARERLA--ELEYLRAALRLWFAQRRLELLEAELE---- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1862 nnlKNEEELTKSKELLNLENKKVEELKKEFEALKLA-AAQKSQQLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLN 1940
Cdd:COG4913    299 ---ELRAELARLEAELERLEARLDALREELDELEAQiRGNGGDRLEQLEREIERLERELEERERR---RARLEALLAALG 372

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1941 NQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRG 2001
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1808-2043 3.88e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.66  E-value: 3.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1808 FEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKEllnlENKKVEEL 1887
Cdd:PLN02939   124 QLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQ----EKIHVEIL 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1888 KKEFEALKLAAAQK-----------SQQLAALQEENVKLAEELGRSRDEVTSHQ-------KLEEERSVLNNQLLEMKKS 1949
Cdd:PLN02939   200 EEQLEKLRNELLIRgateglcvhslSKELDVLKEENMLLKDDIQFLKAELIEVAeteervfKLEKERSLLDASLRELESK 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1950 L---PSNTLRESTLKKEIDEERA-SLQ------KSISDTSALITQKDEELEKLRNEItvlrgeNASAKtlQSVVKTLESD 2019
Cdd:PLN02939   280 FivaQEDVSKLSPLQYDCWWEKVeNLQdlldraTNQVEKAALVLDQNQDLRDKVDKL------EASLK--EANVSKFSSY 351

                          250       260
                   ....*....|....*....|....*
gi 2024460238 2020 KLKL-EEKVKNLEQKLKAKSEQPLT 2043
Cdd:PLN02939   352 KVELlQQKLKLLEERLQASDHEIHS 376
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
767-1100 4.31e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.89  E-value: 4.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  767 EKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 846
Cdd:COG4372      9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  847 LNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 926
Cdd:COG4372     89 LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  927 IQLELTKANEKAV--QLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMIT 1004
Cdd:COG4372    169 LEQELQALSEAEAeqALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1005 KHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERN 1084
Cdd:COG4372    249 EELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKL 328

                          330
                   ....*....|....*.
gi 2024460238 1085 TLKLEKESLLSQHLEM 1100
Cdd:COG4372    329 ELALAILLAELADLLQ 344
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
427-855 4.66e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  427 ELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQisedpeNVATVSEKSRIMELERDLALRVKEVAELRGRLESSkhID 506
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEA------ELEELREELEKLEKLLQLLPLYQELEALEAELAEL--PE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  507 DVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVi 586
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL- 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  587 elwKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENE----------MSNLKLKQENEKSQHLK 656
Cdd:COG4717    226 ---EEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIagvlflvlglLALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  657 EIEALKAkLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVL--QAKCNEQTKLIGSLTQQIRA 734
Cdd:COG4717    303 EAEELQA-LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELeeELQLEELEQEIAALLAEAGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  735 -SEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGgsskvSNLTKELQGKEQKLLDLEKNLSAVNQVKD 813
Cdd:COG4717    382 eDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE-----EELEEELEELEEELEELEEELEELREELA 456

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 2024460238  814 SLEKELQLLKEKftsavDGAENAQRAMQETINKLNQKEEQFA 855
Cdd:COG4717    457 ELEAELEQLEED-----GELAELLQELEELKAELRELAEEWA 493
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 673-1041 4.93e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.43  E-value: 4.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  673 EQTLENLKA-----KLESVEdqhlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQK 747
Cdd:PRK10929    29 TQELEQAKAaktpaQAEIVE-----ALQSALNWLEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPNMS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  748 ANsEGKLEIQKLSEQLQAAEKQIQNlETEKVGGSSKVSNLTKELQGKEQKLL-DLEKNL-------SAVNQVKD-SLEKE 818
Cdd:PRK10929   104 TD-ALEQEILQVSSQLLEKSRQAQQ-EQDRAREISDSLSQLPQQQTEARRQLnEIERRLqtlgtpnTPLAQAQLtALQAE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  819 LQLLKEKftsaVDGAENAQRAM---QETIN---KLNQKeeQFALMSSELEQLKSNLTVMETKLKERE-EREQQLTEAKVK 891
Cdd:PRK10929   182 SAALKAL----VDELELAQLSAnnrQELARlrsELAKK--RSQQLDAYLQALRNQLNSQRQREAERAlESTELLAEQSGD 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  892 LENDIAEIMKSSGDSSAQLmkmndelrlkERQLEQIQLELTKANEKAVQLQKnVEQTAQK-AEQSQ--------QETLKT 962
Cdd:PRK10929   256 LPKSIVAQFKINRELSQAL----------NQQAQRMDLIASQQRQAASQTLQ-VRQALNTlREQSQwlgvsnalGEALRA 324

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  963 HQEELKKM---QDQLTDMkKQMETSQNQYKDLQAKYEKETsemitkhdadikgfkQNLLDAEEALKAAQKK--NDELETQ 1037
Cdd:PRK10929   325 QVARLPEMpkpQQLDTEM-AQLRVQRLRYEDLLNKQPQLR---------------QIRQADGQPLTAEQNRilDAQLRTQ 388


                   ....
gi 2024460238 1038 AEEL 1041
Cdd:PRK10929   389 RELL 392
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1566-1829 5.46e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 5.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1566 ILNRERTELQDKCQKLtG--EVENMKENLTVEKKARVLDKesflleRMELQNNIGFLEKEVEemreknKEFLTEKELLVQ 1643
Cdd:PRK05771    13 TLKSYKDEVLEALHEL-GvvHIEDLKEELSNERLRKLRSL------LTKLSEALDKLRSYLP------KLNPLREEKKKV 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1644 EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHScVSVMLDELQHK-------YEVTEKEKM 1716
Cdd:PRK05771    80 SVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN-FDLDLSLLLGFkyvsvfvGTVPEDKLE 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1717 ELVQENESLHAEWKS-------LVIINEeilkekeklsKEYYKLHEKVVAlleqtDADFScRLLVSEGKH--ELLLEEMS 1787
Cdd:PRK05771   159 ELKLESDVENVEYIStdkgyvyVVVVVL----------KELSDEVEEELK-----KLGFE-RLELEEEGTpsELIREIKE 222

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024460238 1788 NLALKLREIERLQAQTfmqKFEADKRAEEVLQTMEKVTKEKD 1829
Cdd:PRK05771   223 ELEEIEKERESLLEEL---KELAKKYLEELLALYEYLEIELE 261
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2120-2137 5.65e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.65e-04
                           10
                   ....*....|....*...
gi 2024460238 2120 RLFCDICGCFDlHDTEDC 2137
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
46 PHA02562
endonuclease subunit; Provisional
 956-1222 5.71e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 5.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  956 QQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEketsEMITKHDADIKGFKQNLLDAEEALKAAQKkndELE 1035
Cdd:PHA02562   179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQ----NKYDELVEEAKTIKAEIEELTDELLNLVM---DIE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1036 TQAEELKKQAEQAKSLSSVLASARKEIELMSDK------MRDLISEKETLAQERNTLKlekesllsqhlEMESKILLVQQ 1109
Cdd:PHA02562   252 DPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITKIKDKLK-----------ELQHSLEKLDT 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1110 DREELWTKNEELNSENKKILKQKeaaeAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEndalrssestllqqLK 1189
Cdd:PHA02562   321 AIDELEEIMDEFNEQSKKLLELK----NKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE--------------LA 382

                          250       260       270
                   ....*....|....*....|....*....|...
gi 2024460238 1190 ELQANKDAVDVACQKHIKEREELEHYQKLLEEN 1222
Cdd:PHA02562   383 KLQDELDKIVKTKSELVKEKYHRGIVTDLLKDS 415
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 662-1075 5.77e-04

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 44.83  E-value: 5.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  662 KAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEdtlNKLQEAEIKVKELDVLQAK--CNEQTKLIGSLTQQIRASEEKL 739
Cdd:PRK04778    52 KVKKLNLTGQSEEKFEEWRQKWDEIVTNSLPDIE---EQLFEAEELNDKFRFRKAKheINEIESLLDLIEEDIEQILEEL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  740 LDLAALQKANSEGKLEIQKLSEQLQAA---------------EKQIQNLETEKvggsSKVSNLTKE---LQGKEQkLLDL 801
Cdd:PRK04778   129 QELLESEEKNREEVEQLKDLYRELRKSllanrfsfgpaldelEKQLENLEEEF----SQFVELTESgdyVEAREI-LDQL 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  802 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQE--------TINK-LNQKEEQFALMSSELEQLKsnLTVME 872
Cdd:PRK04778   204 EEELAALEQIMEEIPELLKELQTELPDQLQELKAGYRELVEegyhldhlDIEKeIQDLKEQIDENLALLEELD--LDEAE 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  873 TKLKEREEREQQL---TEAKVKLENDIAEIMKSSGDSSAQLMKMNDELrlkerqleqiQLELTkanekavQLQKNVEQTA 949
Cdd:PRK04778   282 EKNEEIQERIDQLydiLEREVKARKYVEKNSDTLPDFLEHAKEQNKEL----------KEEID-------RVKQSYTLNE 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  950 qkaeqSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEkETSEMITKHDADIKGFKQNLLDAEEALKAAQK 1029
Cdd:PRK04778   345 -----SELESVRQLEKQLESLEKQYDEITERIAEQEIAYSELQEELE-EILKQLEEIEKEQEKLSEMLQGLRKDELEARE 418

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 2024460238 1030 KNDELETQAEELKKQAEQAKsLSSVLASARKEIELMSDKMRDLISE 1075
Cdd:PRK04778   419 KLERYRNKLHEIKRYLEKSN-LPGLPEDYLEMFFEVSDEIEALAEE 463
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 430-818 6.36e-04

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 44.85  E-value: 6.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  430 NQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATvsekSRIMELERDLALRVKEVAElrgrlesskhiddvd 509
Cdd:PLN03229   420 NMKKREAVKTPVRELEGEVEKLKEQILKAKESSSKPSELALN----EMIEKLKKEIDLEYTEAVI--------------- 480

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  510 tSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASnermgkenESLKTKLDHANkensdviELW 589
Cdd:PLN03229   481 -AMGLQERLENLREEFSKANSQDQLMHPVLMEKIEKLKDEFNKRLSRAPNY--------LSLKYKLDMLN-------EFS 544

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  590 KSKlesAIASHQQAMEELKVSFNKGVgAQTAEFAELKTQMEKVKLDYENEmsnlKLKQENEKSQHLKEiEALKAKLlEVT 669
Cdd:PLN03229   545 RAK---ALSEKKSKAEKLKAEINKKF-KEVMDRPEIKEKMEALKAEVASS----GASSGDELDDDLKE-KVEKMKK-EIE 614

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  670 EEKEQTLENLKAKLESVEDQHLVEMEDTLNklqeaeikvkelDVLQAKcneqtklIGSLTQQIRASEEKLLDLAALQKAN 749
Cdd:PLN03229   615 LELAGVLKSMGLEVIGVTKKNKDTAEQTPP------------PNLQEK-------IESLNEEINKKIERVIRSSDLKSKI 675

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  750 SEGKLEIQKLSEQLQAAEKQ-IQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKE 818
Cdd:PLN03229   676 ELLKLEVAKASKTPDVTEKEkIEALEQQIKQKIAEALNSSELKEKFEELEAELAAARETAAESNGSLKND 745
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
356-830 7.25e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 7.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  356 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHvlEMEAKMDQLRAMVEAADREKVELLNQLEEE 435
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEELEERLEEL 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  436 KRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLESSKH-IDDVDTSLSL 514
Cdd:COG4717    159 RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEeLEQLENELEA 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  515 LQEISSLQEKM-----AAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANkensdvielw 589
Cdd:COG4717    239 AALEERLKEARlllliAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ---------- 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  590 ksKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKldyenemsnlklkqeneksQHLKEIEALKAKLLEVT 669
Cdd:COG4717    309 --ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ-------------------ELLREAEELEEELQLEE 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  670 EEKEQTLENLKAKLESVEdqhlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRAS--EEKLLDLAALQK 747
Cdd:COG4717    368 LEQEIAALLAEAGVEDEE-----ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEelEEELEELEEELE 442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  748 ANSEgklEIQKLSEQLQAAEKQIQNLETEKvggssKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFT 827
Cdd:COG4717    443 ELEE---ELEELREELAELEAELEQLEEDG-----ELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514


                   ...
gi 2024460238  828 SAV 830
Cdd:COG4717    515 PPV 517
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1033-1634 8.31e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 8.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1033 ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDkMRDLISEKETLAQERNTLKLEKESLlsQHLEMESKILLVQQDRE 1112
Cdd:COG4913    222 DTFEAADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1113 ELwtkneelnsenkkilkQKEAAEAKSRQESTEKvalisekskllsEIETAQADLLKITQendALRSSESTLLQQLKELQ 1192
Cdd:COG4913    299 EL----------------RAELARLEAELERLEA------------RLDALREELDELEA---QIRGNGGDRLEQLEREI 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1193 ANKdavdvacQKHIKERE-ELEHYQKLLEendrvikdkdDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDL 1271
Cdd:COG4913    348 ERL-------ERELEERErRRARLEALLA----------ALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEA 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1272 KSTHIALKNEIDCLLQTNRSLQSEK----EMLLKSREELCvslantanenQALKLRKDE-------MQTELETER----- 1335
Cdd:COG4913    411 EAALRDLRRELRELEAEIASLERRKsnipARLLALRDALA----------EALGLDEAElpfvgelIEVRPEEERwrgai 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1336 ---------------EKLEKMTK--DNMDLKASLSS--LSNFLEEMKSSREASNS--EKIHLLQEALFASEQRLLAER-- 1392
Cdd:COG4913    481 ervlggfaltllvppEHYAAALRwvNRLHLRGRLVYerVRTGLPDPERPRLDPDSlaGKLDFKPHPFRAWLEAELGRRfd 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1393 -------EELVNENKAVT-EKLTKATADA-------------VLAETAfTEKINELNLEKesvfskslqfekhnEALLRE 1451
Cdd:COG4913    561 yvcvdspEELRRHPRAITrAGQVKGNGTRhekddrrrirsryVLGFDN-RAKLAALEAEL--------------AELEEE 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1452 KDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTtlkysIEALEEELKKKNLENQELIAcrsdLSDLLKE 1531
Cdd:COG4913    626 LAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE-----IAELEAELERLDASSDDLAA----LEEQLEE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1532 AQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQK-LTGEVENMKENLTVEKKARVLdKESFLLER 1610
Cdd:COG4913    697 LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGDAVEREL-RENLEERI 775

                          650       660
                   ....*....|....*....|....*
gi 2024460238 1611 MELQNNIGFLEKEVEE-MREKNKEF 1634
Cdd:COG4913    776 DALRARLNRAEEELERaMRAFNREW 800
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
705-1160 9.11e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 9.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  705 EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAE--KQIQNLETEKVGGSS 782
Cdd:COG4717     67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  783 KVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLL----KEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMS 858
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLslatEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  859 SELEQLKSNLTVMETKLKEREEREQQLTEAKV-------KLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLEL 931
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALlallglgGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  932 TKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKdlQAKYEKETSEMITKHDADik 1011
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIAALLAEAGVE-- 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1012 gfkqNLLDAEEALKAAQKKNdELETQAEELKKQAEQAKSLSSVLASARKEIELMsDKMRDLISEKETLAQERNTLKLEKE 1091
Cdd:COG4717    383 ----DEEELRAALEQAEEYQ-ELKEELEELEEQLEELLGELEELLEALDEEELE-EELEELEEELEELEEELEELREELA 456

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024460238 1092 SLLSQHLEMESKILLVQQdREELWTKNEELNSENKKILKQKEAA----EAKSRQESTEKVALISEKSKLLSEI 1160
Cdd:COG4717    457 ELEAELEQLEEDGELAEL-LQELEELKAELRELAEEWAALKLALelleEAREEYREERLPPVLERASEYFSRL 528
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
515-957 9.11e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 9.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  515 LQEISSLQEKMAAAGKEHQ--REMSSLKEKFESSEEALRKEIKTLSASNERMGK--ENESLKTKLDHANKENSDVIELWK 590
Cdd:COG4717     70 LKELKELEEELKEAEEKEEeyAELQEELEELEEELEELEAELEELREELEKLEKllQLLPLYQELEALEAELAELPERLE 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  591 sKLESAIASHQQAMEELKvsfnkgvgAQTAEFAELKTQMEkvklDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTE 670
Cdd:COG4717    150 -ELEERLEELRELEEELE--------ELEAELAELQEELE----ELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  671 EKEQTLENLKAKLESVEDQHlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQ--QIRASEEKLLDLAALQKA 748
Cdd:COG4717    217 EAQEELEELEEELEQLENEL--EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiaGVLFLVLGLLALLFLLLA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  749 NSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEqkLLDLEKNLSAVNQVKDSLEKELQL------L 822
Cdd:COG4717    295 REKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLE--LLDRIEELQELLREAEELEEELQLeeleqeI 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  823 KEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVM--ETKLKEREEREQQLTEAKVKLENDIAEIM 900
Cdd:COG4717    373 AALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELleALDEEELEEELEELEEELEELEEELEELR 452

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238  901 KSSGDSSAQLMKMN-----DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQ 957
Cdd:COG4717    453 EELAELEAELEQLEedgelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
801-1120 9.41e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 9.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  801 LEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 880
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  881 REQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETL 960
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  961 KTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEE 1040
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1041 LKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1120
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 828-1058 1.01e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  828 SAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDsS 907
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE-R 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  908 AQLMKMNDELRLKERQLEQIQlELTKANEKAVQLQKNVEQTAQKAEQ--SQQETLKTHQEELKKMQDQLTDMKKQMETSQ 985
Cdd:COG3883     92 ARALYRSGGSVSYLDVLLGSE-SFSDFLDRLSALSKIADADADLLEElkADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024460238  986 NQYKDLQAKYEKETsemitkhdADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASA 1058
Cdd:COG3883    171 AELEAQQAEQEALL--------AQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 657-805 1.07e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 44.30  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  657 EIEALKAKLLEVTEEKEQtlenLKAKLESVEDQHLVEMEDTLNKLQEaeikvkELDVLQAKCNEQTKLIGSLTQQIRASE 736
Cdd:COG0542    412 ELDELERRLEQLEIEKEA----LKKEQDEASFERLAELRDELAELEE------ELEALKARWEAEKELIEEIQELKEELE 481

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460238  737 EKLLDLAALQKAnsegkleiqklSEQLQAAEKQIQNLETEKVGGS---SKVSNLT-----KELQGKEQKLLDLEKNL 805
Cdd:COG0542    482 QRYGKIPELEKE-----------LAELEEELAELAPLLREEVTEEdiaEVVSRWTgipvgKLLEGEREKLLNLEEEL 547
ClyA_NheA-like cd22654
Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This ...
 727-1006 1.09e-03

Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This model contains Bacillus cereus tripartite non-hemolytic enterotoxin (Nhe) component A (NheA), a member of the cytolysin A (ClyA) family of alpha pore-forming toxins (alpha-PFTs). Non-hemolytic enterotoxin (Nhe), despite its name, is hemolytic and able to lyse erythrocytes from various mammalian organisms. It consists of three proteins, NheA, NheB and NheC, encoded by one operon containing three genes nheA, nheB and nheC, respectively. Separately, these three proteins show no toxicity; maximal activity is seen only when all three components are presented. The NheB and NheC components are able to bind to cell membranes while NheA is not; NheC primes the host cell for the formation of ion permeable NheB/C pores. Binding of NheA to NheB/NheC is thought to be the final stage of pore formation. Structure of NheA shows an elongated, almost entirely alpha-helical protein with an enlarged "head" domain compared with other cytolysins, displaying on its surface an enlarged beta-tongue which is of amphipathic rather than hydrophobic nature. It has been proposed that NheA could even form beta-barrel pores.


Pssm-ID: 439152 [Multi-domain]  Cd Length: 333  Bit Score: 43.41  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  727 SLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNletekvggsskvsnltkelqgkeqkllDLEKNLS 806
Cdd:cd22654     66 NFSQRFNNYYDKLYDLAGKINEDEQAKEDFLNGINKLQSQLQTIQN---------------------------SMEQTSS 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  807 AVNQVKDSLEKELQLLKEKFTSAVD--GAENAQRA-MQETINKLNQ--KEEQFALMSSELEQLKSNLTVMETKLKEREER 881
Cdd:cd22654    119 NLNRFKTLLDADSKNFSTDAKKAIDslSGSNGEIAqLRTQIKTINDeiQEELTKILNRPIEVGDGSINIGKQVFTITITT 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  882 EQQLTEAKVKLENDIAEIMKSSGDssaQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE--QSQQET 959
Cdd:cd22654    199 ATTKTVDVTSIGGLINGIGNASDD---EVKEAANKIQQKQKELVDLIKKLSDAEIQATQLTLVEDQVNGFTEliKRQIAT 275

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2024460238  960 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYE--KETSEMITKH 1006
Cdd:cd22654    276 LENLVEDWEMLNQNMNQLQTNVNSGKIDSKLLQKQLKqiKKISDELNKQ 324
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 1032-1419 1.16e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 43.52  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1032 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1111
Cdd:pfam19220   20 EDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1112 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1191
Cdd:pfam19220  100 REAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRL 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1192 QANKDAVDVACQKHIKEREELEhyqKLLEENDRVIkdkDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDL 1271
Cdd:pfam19220  180 QALSEEQAAELAELTRRLAELE---TQLDATRARL---RALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRMKLEAL 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1272 KSTHIALkneiDCLLQTNRSLQSEKEMLLKSREElcvSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKAS 1351
Cdd:pfam19220  254 TARAAAT----EQLLAEARNQLRDRDEAIRAAER---RLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARAELEER 326

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238 1352 LSSLSNFLEEmKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETA 1419
Cdd:pfam19220  327 AEMLTKALAA-KDAALERAEERIASLSDRIAELTKRFEVERAALEQANRRLKEELQRERAERALAQGA 393
PRK12704 PRK12704
phosphodiesterase; Provisional
 623-759 1.17e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  623 AELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEvteeKEQTLENLKAKLESVEDQHLVEMEDTLNKLQ 702
Cdd:PRK12704    49 KEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQ----KEENLDRKLELLEKREEELEKKEKELEQKQQ 124

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460238  703 EAEIKVKELDVLQAKCNEQTKLIGSLTQqirasEE--KLLdlaaLQKANSEGKLEIQKL 759
Cdd:PRK12704   125 ELEKKEEELEELIEEQLQELERISGLTA-----EEakEIL----LEKVEEEARHEAAVL 174
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1858-2090 1.18e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1858 MLKQNNLKNEEELTKSKELLNlenKKVEELKKEFEAL--KLAAAQKSQQLAALQEENVKLAEELGRSRDEVTshqKLEEE 1935
Cdd:COG3206    161 YLEQNLELRREEARKALEFLE---EQLPELRKELEEAeaALEEFRQKNGLVDLSEEAKLLLQQLSELESQLA---EARAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1936 RSVLNNQLLEMKKSLPSN-----TLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGEnaSAKTLQ 2010
Cdd:COG3206    235 LAEAEARLAALRAQLGSGpdalpELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ--LQQEAQ 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 2011 SVVKTLESDKLKLEEKVKNLEQKLKAKSEQpltvtspsgdiAANLLQDES-AEDKQQEIDFLNSVIVDLQRRNEELNLKI 2089
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEAR-----------LAELPELEAeLRRLEREVEVARELYESLLQRLEEARLAE 381


                   .
gi 2024460238 2090 Q 2090
Cdd:COG3206    382 A 382
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 353-581 1.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRdghdRHVLEMEAKMDQLRAMVEAADREKVELLNQL 432
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  433 EEEKRKVEDL---QFRVEEESITKGDLErkrqiSEDPENVAtvsekSRIMELERDLALRVKEVAELRGRLEsskhidDVD 509
Cdd:COG4942    100 EAQKEELAELlraLYRLGRQPPLALLLS-----PEDFLDAV-----RRLQYLKYLAPARREQAEELRADLA------ELA 163

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238  510 TSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKE 581
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
658-931 1.24e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  658 IEALKAKLLEVTEEkeqtLENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEE 737
Cdd:COG4913    612 LAALEAELAELEEE----LAEAEERLEALEAEL-----DALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  738 KLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggsskVSNLTKELQGKEQKLLDLEKnlSAVNQVKDSLEK 817
Cdd:COG4913    683 SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE-------LEQAEEELDELQDRLEAAED--LARLELRALLEE 753

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  818 EL-QLLKEKFTSAVdgAENAQRAMQETINKLNQKEEQFA-LMSSELEQLKSNLTVMETKLKEREEREQQLTEAK----VK 891
Cdd:COG4913    754 RFaAALGDAVEREL--RENLEERIDALRARLNRAEEELErAMRAFNREWPAETADLDADLESLPEYLALLDRLEedglPE 831

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024460238  892 LENDIAE-IMKSSGDSSAQL-MKMNDELRLKERQLEQIQLEL 931
Cdd:COG4913    832 YEERFKElLNENSIEFVADLlSKLRRAIREIKERIDPLNDSL 873
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
796-1270 1.32e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  796 QKLLDLEKNLSAVNQVKDSLEkELQLLKEKFTSAVDGAEnAQRAMQETINKLnQKEEQFALMSSELEQLKSNLTVMETKL 875
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE-PIRELAERYAAARERLA-ELEYLRAALRLW-FAQRRLELLEAELEELRAELARLEAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  876 KEREEREQQLTEAKVKLENDIAEimkSSGDSSAQLMKmndELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ--KAE 953
Cdd:COG4913    312 ERLEARLDALREELDELEAQIRG---NGGDRLEQLER---EIERLERELEERERRRARLEALLAALGLPLPASAEefAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  954 QSQ-QETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAkyeketsemitkhdaDIKGFKQN-------LLDAEEALK 1025
Cdd:COG4913    386 RAEaAALLEALEEELEALEEALAEAEAALRDLRRELRELEA---------------EIASLERRksniparLLALRDALA 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1026 AA-QKKNDELETQAEELKKQAEQAK--------------SL---SSVLASARKEIE-------LMSDKMRDLISEKETLA 1080
Cdd:COG4913    451 EAlGLDEAELPFVGELIEVRPEEERwrgaiervlggfalTLlvpPEHYAAALRWVNrlhlrgrLVYERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1081 QERNTL--KLE-KESLLSQHLEME--SKILLVQQDREE--------------------LWTKNEE----------LNSEN 1125
Cdd:COG4913    531 LDPDSLagKLDfKPHPFRAWLEAElgRRFDYVCVDSPEelrrhpraitragqvkgngtRHEKDDRrrirsryvlgFDNRA 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1126 KKILKQKEAAEAKSR-QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL---QQLKELQANKDAVDVA 1201
Cdd:COG4913    611 KLAALEAELAELEEElAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAeleAELERLDASSDDLAAL 690

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460238 1202 cqkhikeREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLD 1270
Cdd:COG4913    691 -------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
337-560 1.36e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  337 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALVRDGHDRhVLEMEAKMDQLRA 416
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEA 699

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  417 MVEAADREKVELLNQLEEEKRKVEDLQFRVEE------------ESITKGDLERKRQISEDPENVATVSEksrimELERD 484
Cdd:COG4913    700 ELEELEEELDELKGEIGRLEKELEQAEEELDElqdrleaaedlaRLELRALLEERFAAALGDAVERELRE-----NLEER 774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  485 LALRVKEVAELRGRLESSKH---------IDDVDTSLS-------LLQEISS-----LQEKMAAAGKEH-QREMSSLKEK 542
Cdd:COG4913    775 IDALRARLNRAEEELERAMRafnrewpaeTADLDADLEslpeylaLLDRLEEdglpeYEERFKELLNENsIEFVADLLSK 854

                          250
                   ....*....|....*...
gi 2024460238  543 FESSEEALRKEIKTLSAS 560
Cdd:COG4913    855 LRRAIREIKERIDPLNDS 872
PRK12704 PRK12704
phosphodiesterase; Provisional
 1792-1914 1.45e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1792 KLREIERlQAQTFMQkfEADKRAEEVLQtmEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELdMLKQNNLKN----- 1866
Cdd:PRK12704    32 KIKEAEE-EAKRILE--EAKKEAEAIKK--EALLEAKEEIHKLRNEFEKELRERRNELQKLEKRL-LQKEENLDRklell 105

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024460238 1867 ---EEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1914
Cdd:PRK12704   106 ekrEEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAK 156
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1130-1369 1.76e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1130 KQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQAdllKITQENDALRSSESTLLQQLKELQANkdavdvacqkhikeR 1209
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALER---RIAALARRIRALEQELAALEAELAEL--------------E 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1210 EELEHYQKLLEENDRVIKDKDDVIQRL-QSSYDDLARNQRELLQEVSILTAerdsaqekdldLKSTHIALKNEIDCLLQT 1288
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLgRQPPLALLLSPEDFLDAVRRLQY-----------LKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1289 NRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREA 1368
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   .
gi 2024460238 1369 S 1369
Cdd:COG4942    239 A 239
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1368-1590 2.43e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1368 ASNSEKIHLLQEALFASEQRLlAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEA 1447
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEI-AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1448 LLREKDELERKYSELLDE--KKSLENAFSDMKREQELDFSAKRL--LVQENTTLKYSIEALEEELKKKNLENQELIACRS 1523
Cdd:COG4942     95 LRAELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460238 1524 DLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKE 1590
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PTZ00121 PTZ00121
MAEBL; Provisional
 1794-2036 2.65e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1794 REIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKS 1873
Cdd:PTZ00121  1278 RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD 1357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1874 KELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSN 1953
Cdd:PTZ00121  1358 EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK 1437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1954 TLRESTLKKEIDEERASLQKSISDtsalITQKDEELEKLRNeitvLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQK 2033
Cdd:PTZ00121  1438 KKAEEAKKADEAKKKAEEAKKAEE----AKKKAEEAKKADE----AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK 1509


                   ...
gi 2024460238 2034 LKA 2036
Cdd:PTZ00121  1510 KKA 1512
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1612-2010 2.66e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1612 ELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAele 1691
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ--- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1692 dvhscvsvmLDELQHKYEVTEKEKMELVQENESLHAEWKSLviinEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCR 1771
Cdd:COG4717    127 ---------LLPLYQELEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELLEQLSLATEEE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1772 LLVSEGKHELLLEEMSNL--ALKLREIERLQAQTFMQKFEADKRAEEVLQTMEK-------------------------- 1823
Cdd:COG4717    194 LQDLAEELEELQQRLAELeeELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaallallglggsllslil 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1824 -------------------VTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKV 1884
Cdd:COG4717    274 tiagvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1885 EELKKEFEALKLAAAQKSQQlAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLpsNTLRESTLKKEI 1964
Cdd:COG4717    354 REAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEL--EELLEALDEEEL 430

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 2024460238 1965 DEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQ 2010
Cdd:COG4717    431 EEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1423-1890 3.05e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.70  E-value: 3.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1423 KINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIE 1502
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1503 ALEEELKK-----KNLENQeLIACRSDLSDLLKE-AQDARRTLENELAAVSHAKQVLSS-------SFNTCSSDIEILNR 1569
Cdd:TIGR04523  271 EKQKELEQnnkkiKELEKQ-LNQLKSEISDLNNQkEQDWNKELKSELKNQEKKLEEIQNqisqnnkIISQLNEQISQLKK 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1570 ERTELQDKCQKLTGEVENMKENLTVEKKarvlDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSE 1649
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKK----ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1650 TKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM-------LDELQHKYEVTEKEKMELVQEN 1722
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinkikqnLEQKQKELKSKEKELKKLNEEK 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1723 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADfscrllVSEGKHELLLEEMSNLALKLREIERLQAQ 1802
Cdd:TIGR04523  506 KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD------DFELKKENLEKEIDEKNKEIEELKQTQKS 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1803 TFMQKFEADKRAEEVLQTMEKVTKEKdaihQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENK 1882
Cdd:TIGR04523  580 LKKKQEEKQELIDQKEKEKKDLIKEI----EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655


                   ....*...
gi 2024460238 1883 KVEELKKE 1890
Cdd:TIGR04523  656 EIRNKWPE 663
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 693-976 3.12e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 3.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  693 EMEDTLNKLQEAEIkVKELDVLQAKCNEQTKLIGSLTQQIraseEKLLDLaaLQKANSEGKLEIQKLSE-QLQAAEKQIQ 771
Cdd:PRK05771    17 YKDEVLEALHELGV-VHIEDLKEELSNERLRKLRSLLTKL----SEALDK--LRSYLPKLNPLREEKKKvSVKSLEELIK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  772 NLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDsLEKELQLLKE-KFTSAVDGaenaqramqeTINKlNQK 850
Cdd:PRK05771    90 DVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN-FDLDLSLLLGfKYVSVFVG----------TVPE-DKL 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  851 EEQFALMSS----ELEQLKSNLTVMETKLKEREEreQQLTEAKvKLENDIAEImKSSGDSSAQLMKMNDELRLKERQLEQ 926
Cdd:PRK05771   158 EELKLESDVenveYISTDKGYVYVVVVVLKELSD--EVEEELK-KLGFERLEL-EEEGTPSELIREIKEELEEIEKERES 233

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238  927 IQLELTKANEKAVQLQKNV----EQTAQKAEQSQQ--ETLKT----------HQEELKKMQDQLTD 976
Cdd:PRK05771   234 LLEELKELAKKYLEELLALyeylEIELERAEALSKflKTDKTfaiegwvpedRVKKLKELIDKATG 299
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 548-869 3.30e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 42.64  E-value: 3.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  548 EALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAE----FA 623
Cdd:COG5185    242 ESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEeqlaAA 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  624 ELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEqtLENLKAKLESVEDQHLVEMEDTLNKLQE 703
Cdd:COG5185    322 EAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVE--LSKSSEELDSFKDTIESTKESLDEIPQN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  704 AEIKVKELDVLQAKcneqtkligSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSK 783
Cdd:COG5185    400 QRGYAQEILATLED---------TLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYD 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  784 VSNltkelQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ 863
Cdd:COG5185    471 EIN-----RSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLI 545


                   ....*.
gi 2024460238  864 LKSNLT 869
Cdd:COG5185    546 PASELI 551
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 753-922 3.38e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 3.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  753 KLEIQKLSEQLQAAEKQIQNLETEkvggsskvsnltKELQGKEQKLLDLEKnlsavnqvKDSLEKELQLLKEKFtsavDG 832
Cdd:COG0542    403 RMEIDSKPEELDELERRLEQLEIE------------KEALKKEQDEASFER--------LAELRDELAELEEEL----EA 458

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  833 AENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEreerEQQLTEAKVKlENDIAEIM-KSSG------- 904
Cdd:COG0542    459 LKARWEAEKELIEEIQELKEELEQRYGKIPELEKELAELEEELAE----LAPLLREEVT-EEDIAEVVsRWTGipvgkll 533

                          170
                   ....*....|....*....
gi 2024460238  905 -DSSAQLMKMNDElrLKER 922
Cdd:COG0542    534 eGEREKLLNLEEE--LHER 550
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1833-1951 3.48e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.51  E-value: 3.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1833 QEKIETL-ASLENSRQTNEKLQNELDMLKQNNLKNEEELtkskellnleNKKVEELKKEFEALKLAAAQKSQQ-LAALQE 1910
Cdd:PRK00409   515 KEKLNELiASLEELERELEQKAEEAEALLKEAEKLKEEL----------EEKKEKLQEEEDKLLEEAEKEAQQaIKEAKK 584

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2024460238 1911 ENVKLAEELGRSRDEVTSHQK---LEEERSVLNNQLLEMKKSLP 1951
Cdd:PRK00409   585 EADEIIKELRQLQKGGYASVKaheLIEARKRLNKANEKKEKKKK 628
PRK11281 PRK11281
mechanosensitive channel MscK;
1814-1985 3.51e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1814 AEEVLQTMEKVTKEKDAIHQEK---------IETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKskellnLENKKV 1884
Cdd:PRK11281    38 EADVQAQLDALNKQKLLEAEDKlvqqdleqtLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEA------LKDDND 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1885 EELKKEFEALKLAA-----AQKSQQLAALQE------------------------ENVKLAEEL---------GRSRDEV 1926
Cdd:PRK11281   112 EETRETLSTLSLRQlesrlAQTLDQLQNAQNdlaeynsqlvslqtqperaqaalyANSQRLQQIrnllkggkvGGKALRP 191

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238 1927 TSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEID---EERASLQKSISDTSALITQK 1985
Cdd:PRK11281   192 SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDyltARIQRLEHQLQLLQEAINSK 253
PRK11281 PRK11281
mechanosensitive channel MscK;
842-1212 3.60e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  842 ETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND------ 915
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLStlslrq 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  916 -ELRLKER--QLEQIQLELTKANEKAVQLQKNVEQtAQKA-EQSQQETlkthqEELKKMQDQLTDMKKQMETSQnqykdl 991
Cdd:PRK11281   126 lESRLAQTldQLQNAQNDLAEYNSQLVSLQTQPER-AQAAlYANSQRL-----QQIRNLLKGGKVGGKALRPSQ------ 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  992 QAKYEKETSEMITKHDadikgFKQNLLDAEEALKA-AQKKNDELetqAEELKKQAEQAKSLSSVLASarKEIELMSDKMR 1070
Cdd:PRK11281   194 RVLLQAEQALLNAQND-----LQRKSLEGNTQLQDlLQKQRDYL---TARIQRLEHQLQLLQEAINS--KRLTLSEKTVQ 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1071 DLISEKETLAQERNTLkLEKESLLSQHLemeSKILLVQQDR------EELWTKN--EELNSENKKILKQKEAAEAK---S 1139
Cdd:PRK11281   264 EAQSQDEAARIQANPL-VAQELEINLQL---SQRLLKATEKlntltqQNLRVKNwlDRLTQSERNIKEQISVLKGSlllS 339

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460238 1140 RQESTEKVALISekSKLLSEIETAQADL----LKITQENDALrSSESTLLQQLKELQANK--DAVDVACQKHIKEREEL 1212
Cdd:PRK11281   340 RILYQQQQALPS--ADLIEGLADRIADLrleqFEINQQRDAL-FQPDAYIDKLEAGHKSEvtDEVRDALLQLLDERREL 415
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 355-713 3.71e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  355 QEALK-EKQQHIEQLLAERDLERAEVAKAtshvGEIEQELALVRDgHDRHVLEMEAKMDQLRamveaadrekvellnqLE 433
Cdd:pfam17380  298 QERLRqEKEEKAREVERRRKLEEAEKARQ----AEMDRQAAIYAE-QERMAMERERELERIR----------------QE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  434 EEKRKVEdlqfRVEEESITkgdlerkrqisedpenvatvSEKSRIMELERDLALRVKEVAELRGRLESSKH--IDDVDTS 511
Cdd:pfam17380  357 ERKRELE----RIRQEEIA--------------------MEISRMRELERLQMERQQKNERVRQELEAARKvkILEEERQ 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  512 LSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTK---LDHANKENSDVIEL 588
Cdd:pfam17380  413 RKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKkleLEKEKRDRKRAEEQ 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  589 WKSKLESAIASHQQAMEElkvsfnkgvgaQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEV 668
Cdd:pfam17380  493 RRKILEKELEERKQAMIE-----------EERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKA 561

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 2024460238  669 TEEkeqtlenlKAKLESVEDQhlvemEDTLNKLQEAEIKVKELDV 713
Cdd:pfam17380  562 TEE--------RSRLEAMERE-----REMMRQIVESEKARAEYEA 593
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 664-1096 3.74e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.63  E-value: 3.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  664 KLLEVTEEKEQTLENLKAKLESVEDQHlVEMEDTLNKLQEAEikvKELDV-LQAkCNEQTKLIGSLTQQIRASEEKLLDL 742
Cdd:COG3096    282 ELSERALELRRELFGARRQLAEEQYRL-VEMARELEELSARE---SDLEQdYQA-ASDHLNLVQTALRQQEKIERYQEDL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  743 AALqkansEGKLEIQklSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLldleknlsavnqvkdsleKELQLL 822
Cdd:COG3096    357 EEL-----TERLEEQ--EEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQAL------------------DVQQTR 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  823 KEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKS 902
Cdd:COG3096    412 AIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERS 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  903 SGDSSA-QLMKMNDELRLKERQLEQIQLELTKAnEKAVQLQKNVEQTAQKAEQSQ------QETLKTHQEELKKMQDQLT 975
Cdd:COG3096    492 QAWQTArELLRRYRSQQALAQRLQQLRAQLAEL-EQRLRQQQNAERLLEEFCQRIgqqldaAEELEELLAELEAQLEELE 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  976 DmkkQMETSQNQYKDLQAKyeketsemitkhdadikgfkqnlldaEEALKAAQKkndELETQAEELKKQAEQAKSLSSVL 1055
Cdd:COG3096    571 E---QAAEAVEQRSELRQQ--------------------------LEQLRARIK---ELAARAPAWLAAQDALERLREQS 618

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2024460238 1056 ASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQ 1096
Cdd:COG3096    619 GEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQ 659
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1809-1949 3.76e-03

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 42.15  E-value: 3.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1809 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELlnleNKKVEELK 1888
Cdd:pfam06160  267 EIEERIDQLYDLLEKEVDAKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGL----EKQLEELE 342

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238 1889 KEFEALKLAAAQKSQ--------------QLAALQEENVKLAEELGRSR-DEVTSHQKLEEERSVLNNQLLEMKKS 1949
Cdd:pfam06160  343 KRYDEIVERLEEKEVayselqeeleeileQLEEIEEEQEEFKESLQSLRkDELEAREKLDEFKLELREIKRLVEKS 418
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 841-1027 4.47e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 4.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  841 QETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLM--KMNDELR 918
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvRNNKEYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  919 LKERQLEQIQLELTKANEKAVQLQKNVEQtaqkaeqsqqetlktHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKE 998
Cdd:COG1579     93 ALQKEIESLKRRISDLEDEILELMERIEE---------------LEEELAELEAELAELEAELEEKKAELDEELAELEAE 157

                          170       180
                   ....*....|....*....|....*....
gi 2024460238  999 TSEMITKHDADIKGFKQNLLDAEEALKAA 1027
Cdd:COG1579    158 LEELEAEREELAAKIPPELLALYERIRKR 186
CCDC73 pfam15818
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ...
 1599-2025 4.53e-03

Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.


Pssm-ID: 464893 [Multi-domain]  Cd Length: 1048  Bit Score: 42.24  E-value: 4.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1599 RVLDKESFLLERME-----------LQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETE 1667
Cdd:pfam15818    1 QLLDFKTSLLEALEelrmrreaetqYEEQIGKIIVETQELKWQKETLQNQKETLAKQHKEAMAVFKKQLQMKMCALEEEK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1668 ---QLASK-----IEQLKSDFTSLSVSKAELEDVhscVSVMLDELQ----------------HKYEVTEKEKMELVQEN- 1722
Cdd:pfam15818   81 gkyQLATEikekeIEGLKETLKALQVSKYSLQKK---VSEMEQKLQlhllakedhhkqlneiEKYYATITGQFGLVKENh 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1723 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKvvalLEQTDADFSCRLLVSEGKHElllEEMSNLALKLREIERLQAQ 1802
Cdd:pfam15818  158 GKLEQNVQEAIQLNKRLSALNKKQESEICSLKKE----LKKVTSDLIKSKVTCQYKMG---EENINLTIKEQKFQELQER 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1803 TFMQkfeadkraeevLQTMEKVTKEKDAIHQEKIETLAS-------LENSRQTNEKLQNELDMLKQNN--LKNEEELTKS 1873
Cdd:pfam15818  231 LNME-----------LELNKKINEEITHIQEEKQDIIISfqhmqqlLQQQTQANTEMEAELKALKENNqtLERDNELQRE 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1874 K------ELLNLENKKVEEL---KKEFEALKLAAAQKSQQLAALQEENVKLAEElgrsRDEVTSHQKLEEERSVLNNQLL 1944
Cdd:pfam15818  300 KvkeneeKFLNLQNEHEKALgtwKKHVEELNGEINEIKNELSSLKETHIKLQEH----YNKLCNQKKFEEDKKFQNVPEV 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1945 EMKKS-LPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKL 2023
Cdd:pfam15818  376 NNENSeMSTEKSENLIIQKYNSEQEIREENTKSFCSDTEYRETEKKKGPPVEEIIIEDLQVLEKSFKNEIDTSVPQDKNQ 455


                   ..
gi 2024460238 2024 EE 2025
Cdd:pfam15818  456 SE 457
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
834-1176 4.62e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.81  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  834 ENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKM 913
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  914 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQA 993
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEE-LQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQE 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  994 KYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLI 1073
Cdd:COG4372    165 ELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALEL 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1074 SEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEK 1153
Cdd:COG4372    245 EEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLEL 324

                          330       340
                   ....*....|....*....|...
gi 2024460238 1154 SKLLSEIETAQADLLKITQENDA 1176
Cdd:COG4372    325 AKKLELALAILLAELADLLQLLL 347
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1809-1950 4.73e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.13  E-value: 4.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1809 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELlnleNKKVEELK 1888
Cdd:PRK04778   286 EIQERIDQLYDILEREVKARKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQL----EKQLESLE 361

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460238 1889 KEFEALKLAAAQKSQ---QLAALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEMKKSL 1950
Cdd:PRK04778   362 KQYDEITERIAEQEIaysELQEELEEILKQLEEIEKEQEKLSEMlQGLRKDELEAREKLERYRNKL 427
PLN02939 PLN02939
transferase, transferring glycosyl groups
 802-1169 5.10e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.20  E-value: 5.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  802 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRamqeTINKLNQKEEQfAL-----MSSELEQLKSNLTVMETKLK 876
Cdd:PLN02939   106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEK----NILLLNQARLQ-ALedlekILTEKEALQGKINILEMRLS 180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  877 EREEREQQLTEAKVKLEndiaeimkssgdssaqlmkmndelrLKERQLEQIQLELTK--ANEKAVQLQKNVEQTAQKAEQ 954
Cdd:PLN02939   181 ETDARIKLAAQEKIHVE-------------------------ILEEQLEKLRNELLIrgATEGLCVHSLSKELDVLKEEN 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  955 SqqeTLKTHQEELKKMQDQLTDMKKQMetsqnqykdlqAKYEKETSEMitkhDADIKGFKQNLLDAEEAL--------KA 1026
Cdd:PLN02939   236 M---LLKDDIQFLKAELIEVAETEERV-----------FKLEKERSLL----DASLRELESKFIVAQEDVsklsplqyDC 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1027 AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRD-----LISEKETLAQERntLKLEKESLLSQHLEME 1101
Cdd:PLN02939   298 WWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEanvskFSSYKVELLQQK--LKLLEERLQASDHEIH 375

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460238 1102 SKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSrqESTEKVALISEKSKLLSEIETAQADLLK 1169
Cdd:PLN02939   376 SYIQLYQESIKEFQDTLSKLKEESKKRSLEHPADDMPS--EFWSRILLLIDGWLLEKKISNNDAKLLR 441
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 932-1051 5.52e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 41.25  E-value: 5.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  932 TKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMkkqmetsQNQYKDLQAKYEKETsemitkhdadik 1011
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATA-------QKELANAQAQALQTA------------ 316

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 2024460238 1012 gfKQNLLDAEEALKAAQKKNDELETQAEELK-KQAEQAKSL 1051
Cdd:TIGR04320  317 --QNNLATAQAALANAEARLAKAKEALANLNaDLAKKQAAL 355
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 548-781 5.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  548 EALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKsKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKT 627
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR-ALEQELAALEAELAELEKEIAELRAELEAQKEELAE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  628 QMEKVKLDYENEMSNLKLKQENeKSQHLKEIEALKAkLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIK 707
Cdd:COG4942    109 LLRALYRLGRQPPLALLLSPED-FLDAVRRLQYLKY-LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024460238  708 VKELDVLQAkcnEQTKLIGSLTQQIRASEEKlldLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 781
Cdd:COG4942    187 RAALEALKA---ERQKLLARLEKELAELAAE---LAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
PRK12704 PRK12704
phosphodiesterase; Provisional
 745-901 6.23e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 6.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  745 LQKANSEGKlEIQKlsEQLQAAEKQIQNL--ETEKvggssKVSNLTKELQGKEQKLLDLEKNlsavnqvkdsLEKELQLL 822
Cdd:PRK12704    44 LEEAKKEAE-AIKK--EALLEAKEEIHKLrnEFEK-----ELRERRNELQKLEKRLLQKEEN----------LDRKLELL 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  823 KEKftsavdgaenaQRAMQETINKLNQKEEQFALMSSELEQLKSN-LTVME--TKLKEREEREQQLTEAKVKLENDIAEI 899
Cdd:PRK12704   106 EKR-----------EEELEKKEKELEQKQQELEKKEEELEELIEEqLQELEriSGLTAEEAKEILLEKVEEEARHEAAVL 174


                   ..
gi 2024460238  900 MK 901
Cdd:PRK12704   175 IK 176
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 407-711 6.25e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.84  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  407 MEAKMDQLRAMveAADREKVELLNQL-EEEKRKVEDLQFRVEEESITKgDLERKRQISEDPENVATVSEKSRImELERDL 485
Cdd:PRK05771     2 APVRMKKVLIV--TLKSYKDEVLEALhELGVVHIEDLKEELSNERLRK-LRSLLTKLSEALDKLRSYLPKLNP-LREEKK 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  486 ALRVKEVAELRGRLES--SKHIDDVDtslSLLQEISSLQEKMaaagKEHQREMSSLK--EKFESSEEALRKEiKTLSASN 561
Cdd:PRK05771    78 KVSVKSLEELIKDVEEelEKIEKEIK---ELEEEISELENEI----KELEQEIERLEpwGNFDLDLSLLLGF-KYVSVFV 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  562 ERMGKENESLktklDHANKENSDVIELWKSKLES--AIASHQQAMEELkvsfnkgvgaqtaeFAELKtqmekvkldyENE 639
Cdd:PRK05771   150 GTVPEDKLEE----LKLESDVENVEYISTDKGYVyvVVVVLKELSDEV--------------EEELK----------KLG 201

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460238  640 MSNLKLKQENEKSQhlkEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKEL 711
Cdd:PRK05771   202 FERLELEEEGTPSE---LIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEALSKFL 270
PRK11281 PRK11281
mechanosensitive channel MscK;
989-1292 6.61e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 6.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  989 KDLQAKYEKETSemITKHDADIKGFKQNLLDAEEALKAAQKKNDELEtqaeELKKQAEQAKSLssvLASARKEIELMSDk 1068
Cdd:PRK11281    39 ADVQAQLDALNK--QKLLEAEDKLVQQDLEQTLALLDKIDRQKEETE----QLKQQLAQAPAK---LRQAQAELEALKD- 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1069 mrdliSEKETLAQERNTLKLEkesllsqhlEMESKILLVQQDREELwtkNEELNSENKKILKQkeaaeaksrQESTEKV- 1147
Cdd:PRK11281   109 -----DNDEETRETLSTLSLR---------QLESRLAQTLDQLQNA---QNDLAEYNSQLVSL---------QTQPERAq 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1148 ALISEKSKLLSEIETaqadLLKITQEND-ALRSSESTLLQ------------QLKELQANKDAVDVACQKHIKEREE--- 1211
Cdd:PRK11281   163 AALYANSQRLQQIRN----LLKGGKVGGkALRPSQRVLLQaeqallnaqndlQRKSLEGNTQLQDLLQKQRDYLTARiqr 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1212 LEHYQKLLEE--NDRVIKDKDDVIQRLQSSyDDLARNQ--RELLQEVSILTAERD---SAQEKDLDLKSTHIALKNEIDC 1284
Cdd:PRK11281   239 LEHQLQLLQEaiNSKRLTLSEKTVQEAQSQ-DEAARIQanPLVAQELEINLQLSQrllKATEKLNTLTQQNLRVKNWLDR 317


                   ....*...
gi 2024460238 1285 LLQTNRSL 1292
Cdd:PRK11281   318 LTQSERNI 325
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 535-1533 7.56e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.58  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  535 EMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANK--------ENSDVIELWKSKLESAIASHQQAMEE 606
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDvadkaisnDDPEEIEKKIENIVTKIDKKKNIYDE 1191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  607 LKVSFNkgvgaQTAEFAELKTQMEKVK---LDYENEMSNLKLKQ---ENEKSQHLkeIEALKAKLlevteekeQTLENLK 680
Cdd:TIGR01612 1192 IKKLLN-----EIAEIEKDKTSLEEVKginLSYGKNLGKLFLEKideEKKKSEHM--IKAMEAYI--------EDLDEIK 1256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  681 AKLESVEDQHLVEMEDT--LNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQK 758
Cdd:TIGR01612 1257 EKSPEIENEMGIEMDIKaeMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  759 LSEQLQAAEKQIQNL-ETEKVGGSSKVSNLTKELQGKEQKL-----LDLEKNLSAVNQVKDSLEkeLQLLKEKFTSAVDG 832
Cdd:TIGR01612 1337 HNSDINLYLNEIANIyNILKLNKIKKIIDEVKEYTKEIEENnknikDELDKSEKLIKKIKDDIN--LEECKSKIESTLDD 1414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  833 AEnaqraMQETINKLnqKEEQFALMSSEleqlkSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMK 912
Cdd:TIGR01612 1415 KD-----IDECIKKI--KELKNHILSEE-----SNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKKDNATNDHD 1482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  913 MN-DELRLKERQLEQIQlelTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQltdMKKQMETSQNQYKDL 991
Cdd:TIGR01612 1483 FNiNELKEHIDKSKGCK---DEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAK---TKKDSEIIIKEIKDA 1556

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  992 QAKY--EKETSEMITKhdaDIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKM 1069
Cdd:TIGR01612 1557 HKKFilEAEKSEQKIK---EIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKI 1633

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1070 RDL-ISEKETLAQER----NTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKK-----ILKQKEAAEAKS 1139
Cdd:TIGR01612 1634 SSFsIDSQDTELKENgdnlNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNyeigiIEKIKEIAIANK 1713

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1140 RQESTEKVALISEKSKLLSEIETAqaDLLKI----------TQENDALR----------------SSESTLLQQLKELQA 1193
Cdd:TIGR01612 1714 EEIESIKELIEPTIENLISSFNTN--DLEGIdpnekleeynTEIGDIYEefielyniiagcletvSKEPITYDEIKNTRI 1791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1194 NkdavdvACQKHIKEREELEHYQKLLE-----ENDRVI----KDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSA 1264
Cdd:TIGR01612 1792 N------AQNEFLKIIEIEKKSKSYLDdieakEFDRIInhfkKKLDHVNDKFTKEYSKINEGFDDISKSIENVKNSTDEN 1865

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1265 QEKDLdLKSTHIALKNEIDcllQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKD---EMQTELETEREKLEKM 1341
Cdd:TIGR01612 1866 LLFDI-LNKTKDAYAGIIG---KKYYSYKDEAEKIFINISKLANSINIQIQNNSGIDLFDNiniAILSSLDSEKEDTLKF 1941

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1342 TKDNMDLKASLSSLSN----FLEEMKSSREASNSEKihllQEALFASEQRLLAEREELVNENKAVTEKlTKATADAVLAE 1417
Cdd:TIGR01612 1942 IPSPEKEPEIYTKIRDsydtLLDIFKKSQDLHKKEQ----DTLNIIFENQQLYEKIQASNELKDTLSD-LKYKKEKILND 2016

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1418 TAFT-EKINELN------------LE---KESVFSKSLQFEKHNEALLREKD--ELERKYSELLDEKKSLENAFSDMKRE 1479
Cdd:TIGR01612 2017 VKLLlHKFDELNklscdsqnydtiLElskQDKIKEKIDNYEKEKEKFGIDFDvkAMEEKFDNDIKDIEKFENNYKHSEKD 2096

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024460238 1480 QELDFSAKRLLVQENTTLKYSIEALEEELKKknLENQelIACRSDLSDLLKEAQ 1533
Cdd:TIGR01612 2097 NHDFSEEKDNIIQSKKKLKELTEAFNTEIKI--IEDK--IIEKNDLIDKLIEMR 2146
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1500-2117 7.64e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.50  E-value: 7.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1500 SIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRErteLQDKCQ 1579
Cdd:pfam02463  189 IIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE---IEKEEE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1580 KLTGEVENMKENLTVEKKARVLDKESFLLERmELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEK 1659
Cdd:pfam02463  266 KLAQVLKENKEEEKEKKLQEEELKLLAKEEE-ELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1660 MILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEI 1739
Cdd:pfam02463  345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1740 LKEK------EKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQ-----TFMQKF 1808
Cdd:pfam02463  425 KKEEleileeEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQkleerSQKESK 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1809 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1888
Cdd:pfam02463  505 ARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1889 KEFEALKLAAAQKS--------QQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTL 1960
Cdd:pfam02463  585 PKLKLPLKSIAVLEidpilnlaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1961 KKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKS-- 2038
Cdd:pfam02463  665 KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKqk 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 2039 ----EQPLTVTSPSGDIAANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRMCEAALNGNEEETINYDSEEEGL 2114
Cdd:pfam02463  745 ideeEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824


                   ...
gi 2024460238 2115 SKK 2117
Cdd:pfam02463  825 EQE 827
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1040-1276 8.21e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 8.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1040 ELKKQAEQAKSLSSVLASARKeIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEmeSKILLVQQDREELWTKNE 1119
Cdd:PRK05771    34 EDLKEELSNERLRKLRSLLTK-LSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVE--EELEKIEKEIKELEEEIS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1120 ELNSENKKILKQKEAAE----------AKSRQESTE-KVALISEKSKLLSEIETAQADLLKITQEND-------ALRSSE 1181
Cdd:PRK05771   111 ELENEIKELEQEIERLEpwgnfdldlsLLLGFKYVSvFVGTVPEDKLEELKLESDVENVEYISTDKGyvyvvvvVLKELS 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238 1182 STLLQQLKELQAnkDAVDVACQKHIKEReeLEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELlqevsiLTAER 1261
Cdd:PRK05771   191 DEVEEELKKLGF--ERLELEEEGTPSEL--IREIKEELEEIEKERESLLEELKELAKKYLEELLALYEY------LEIEL 260

                          250
                   ....*....|....*
gi 2024460238 1262 DSAQEKDLDLKSTHI 1276
Cdd:PRK05771   261 ERAEALSKFLKTDKT 275
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
365-566 9.12e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 9.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  365 IEQLLAERDLERAEVAKATShvGEIEQELALVRDghdrHVLEMEAKMDQLRA---MVEAADREKVeLLNQLEEEKRKVED 441
Cdd:COG3206    158 AEAYLEQNLELRREEARKAL--EFLEEQLPELRK----ELEEAEAALEEFRQkngLVDLSEEAKL-LLQQLSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  442 LQFRVEEESITKGDLERkrQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLeSSKHIDDVdtslSLLQEISSL 521
Cdd:COG3206    231 ARAELAEAEARLAALRA--QLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARY-TPNHPDVI----ALRAQIAAL 303

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2024460238  522 QEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGK 566
Cdd:COG3206    304 RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE 348
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 747-1084 9.41e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 40.99  E-value: 9.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  747 KANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKElqgKEQKLLDLEKNLSAVNQvkdSLEKELQLLKEKF 826
Cdd:PLN03229   422 KKREAVKTPVRELEGEVEKLKEQILKAKESSSKPSELALNEMIE---KLKKEIDLEYTEAVIAM---GLQERLENLREEF 495

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  827 TSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLtvmeTKLKEReEREQQLTEAKVKLENDIAEIMKssgds 906
Cdd:PLN03229   496 SKANSQDQLMHPVLMEKIEKLKDEFNKRLSRAPNYLSLKYKL----DMLNEF-SRAKALSEKKSKAEKLKAEINK----- 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  907 saQLMKMNDELRLKERqLEQIQLELTKAN-EKAVQLQKNVEQTAQKAEQSQQETLKthqEELKKMQDQLTDM-KKQMETS 984
Cdd:PLN03229   566 --KFKEVMDRPEIKEK-MEALKAEVASSGaSSGDELDDDLKEKVEKMKKEIELELA---GVLKSMGLEVIGVtKKNKDTA 639

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  985 QNQ-YKDLQAKYEK---ETSEMITK--HDADIKGfKQNLLDAEEAlKAAQKKNDELETQAEELKKQAEQakSLSSVLASA 1058
Cdd:PLN03229   640 EQTpPPNLQEKIESlneEINKKIERviRSSDLKS-KIELLKLEVA-KASKTPDVTEKEKIEALEQQIKQ--KIAEALNSS 715

                          330       340
                   ....*....|....*....|....*.
gi 2024460238 1059 rkEIELMSDKMRDLISEKETLAQERN 1084
Cdd:PLN03229   716 --ELKEKFEELEAELAAARETAAESN 739
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 754-928 9.69e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 9.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  754 LEIQK---LSEQL-QAAEKQIQNlETEKVGGS-SKVSNLTKELqgkEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTS 828
Cdd:PRK00409   491 FEIAKrlgLPENIiEEAKKLIGE-DKEKLNELiASLEELEREL---EQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDK 566

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460238  829 AVDGAE--------NAQRAMQETINKLN--QKEEQFALMSSELE----QLKSNLTVMETKLKEREEREQQLT---EAKVK 891
Cdd:PRK00409   567 LLEEAEkeaqqaikEAKKEADEIIKELRqlQKGGYASVKAHELIearkRLNKANEKKEKKKKKQKEKQEELKvgdEVKYL 646

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2024460238  892 LENDIAEIMKSSGDSSAQ----LMKMndelRLKERQLEQIQ 928
Cdd:PRK00409   647 SLGQKGEVLSIPDDKEAIvqagIMKM----KVPLSDLEKIQ 683
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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