|
Name |
Accession |
Description |
Interval |
E-value |
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
592-700 |
8.36e-26 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 102.88 E-value: 8.36e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 592 CGGELTAMA-GVILSPNWPEPYTEGEDCIWRVHVGEEKRLFLDIQLLNLTNS-----DILTIYDGDELSARILGQYVGSS 665
Cdd:cd00041 1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80
|
90 100 110
....*....|....*....|....*....|....*
gi 2024460663 666 GPQKLYSSSPDLTIRFHSDPAglifGKGQGFIMNY 700
Cdd:cd00041 81 LPPPIISSGNSLTVRFRSDSS----VTGRGFKATY 111
|
|
| CUB |
pfam00431 |
CUB domain; |
592-687 |
1.01e-20 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 88.12 E-value: 1.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 592 CGGELTAMAGVILSPNWPEPYTEGEDCIWRVHVGEEKRLFLDIQLLNLTNS-----DILTIYDGDELSARILGQYVGSSG 666
Cdd:pfam00431 1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHdecgyDYVEIRDGPSASSPLLGRFCGSGI 80
|
90 100
....*....|....*....|.
gi 2024460663 667 PQKLYSSSPDLTIRFHSDPAG 687
Cdd:pfam00431 81 PEDIVSSSNQMTIKFVSDASV 101
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
601-700 |
5.66e-18 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 80.13 E-value: 5.66e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 601 GVILSPNWPEPYTEGEDCIWRVHVGEEKRLFLDIQLLNLTNS-----DILTIYDGDELSARILGQYVGSSGPQKLYSS-S 674
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSsS 80
|
90 100
....*....|....*....|....*.
gi 2024460663 675 PDLTIRFHSDPAglifGKGQGFIMNY 700
Cdd:smart00042 81 NSLTLTFVSDSS----VQKRGFSARY 102
|
|
| PHA02927 |
PHA02927 |
secreted complement-binding protein; Provisional |
709-894 |
1.08e-13 |
|
secreted complement-binding protein; Provisional
Pssm-ID: 222943 [Multi-domain] Cd Length: 263 Bit Score: 72.38 E-value: 1.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 709 CSDLPEIQNGWKTTSHTELvrGAKITYQCDPGYDIVGSDTLTCQW----DLSWSSDPPFCEKIMyCTDPGEVEHSTRLIS 784
Cdd:PHA02927 86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESVK-CQSPPSISNGRHNGY 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 785 DPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPiwtsrlPHCvseESLACDNPGLpENGY-QILYKRLYLPGESLTF 863
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP------PTC---QIVKCPHPTI-SNGYlSSGFKRSYSYNDNVDF 232
|
170 180 190
....*....|....*....|....*....|.
gi 2024460663 864 MCYEGFELMGEVTIKCILGqpSHWSGPLPIC 894
Cdd:PHA02927 233 KCKYGYKLSGSSSSTCSPG--NTWQPELPKC 261
|
|
| CCP |
cd00033 |
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ... |
709-765 |
3.20e-13 |
|
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Pssm-ID: 153056 [Multi-domain] Cd Length: 57 Bit Score: 65.18 E-value: 3.20e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460663 709 CSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 765
Cdd:cd00033 1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
|
|
| CCP |
smart00032 |
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ... |
709-764 |
3.96e-13 |
|
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
Pssm-ID: 214478 [Multi-domain] Cd Length: 56 Bit Score: 64.86 E-value: 3.96e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460663 709 CSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 764
Cdd:smart00032 1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
416-525 |
2.59e-12 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 64.36 E-value: 2.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 416 CGGTVHNATIGRVLSPSTAGNQSGSMYCVWAITAPPGQKLHLHFEKLLLAE-----RDRMVVYSGDSNRSAVLyDSLRAD 490
Cdd:cd00041 1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESspncsYDYLEIYDGPSTSSPLL-GRFCGS 79
|
90 100 110
....*....|....*....|....*....|....*
gi 2024460663 491 SVPFEgVISDDSSIRIDFLAEEPAASTAFNIRFEA 525
Cdd:cd00041 80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| Sushi |
pfam00084 |
Sushi repeat (SCR repeat); |
709-764 |
4.21e-12 |
|
Sushi repeat (SCR repeat);
Pssm-ID: 459664 [Multi-domain] Cd Length: 56 Bit Score: 61.75 E-value: 4.21e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460663 709 CSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 764
Cdd:pfam00084 1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
20-199 |
9.90e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.50 E-value: 9.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 20 APRPDG--------RPEAAPLPASPRpLPADEAsmGGPRQGAALNLLPAAEDSPKPAVEGPSLRAQSHISPAPTTDPGAD 91
Cdd:PHA03247 2574 APRPSEpavtsrarRPDAPPQSARPR-APVDDR--GDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPE 2650
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 92 TKQTFPAkkkPPALKHSNTARKQLKA--------KPTLPGLSRAV-STQGSVLPVSSQEPSIPMETADGQRQSPPELPGW 162
Cdd:PHA03247 2651 RPRDDPA---PGRVSRPRRARRLGRAaqassppqRPRRRAARPTVgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAA 2727
|
170 180 190
....*....|....*....|....*....|....*..
gi 2024460663 163 GPTSRPLLQISPFTPVPSTAQPFPGGPGDVGTGPTAA 199
Cdd:PHA03247 2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTA 2764
|
|
| Sushi |
pfam00084 |
Sushi repeat (SCR repeat); |
531-588 |
7.32e-09 |
|
Sushi repeat (SCR repeat);
Pssm-ID: 459664 [Multi-domain] Cd Length: 56 Bit Score: 52.50 E-value: 7.32e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460663 531 CYEP-YIQNGNFTTSDPTYNLGTTVEFTCDPGHSLeQGPAVIECVNmrDPYWNDTEPLC 588
Cdd:pfam00084 1 CPPPpDIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
|
|
| CCP |
cd00033 |
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ... |
531-589 |
3.55e-08 |
|
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Pssm-ID: 153056 [Multi-domain] Cd Length: 57 Bit Score: 50.92 E-value: 3.55e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 531 CYEPY-IQNGNFTTSDPTYNLGTTVEFTCDPGHSLeQGPAVIECvnMRDPYWNDTEPLCR 589
Cdd:cd00033 1 CPPPPvPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITC--TENGGWSPPPPTCE 57
|
|
| CCP |
smart00032 |
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ... |
534-588 |
3.95e-08 |
|
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
Pssm-ID: 214478 [Multi-domain] Cd Length: 56 Bit Score: 50.60 E-value: 3.95e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 2024460663 534 PYIQNGNFTTSDPTYNLGTTVEFTCDPGHSLeQGPAVIECVNmrDPYWNDTEPLC 588
Cdd:smart00032 5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
|
|
| CUB |
pfam00431 |
CUB domain; |
416-523 |
1.82e-07 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 50.37 E-value: 1.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 416 CGGTVHNATiGRVLSPSTAGNQSGSMYCVWAITAPPGQKLHLHFEKLLLAERDR-----MVVYSGDSnRSAVLYDSLRAD 490
Cdd:pfam00431 1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDEcgydyVEIRDGPS-ASSPLLGRFCGS 78
|
90 100 110
....*....|....*....|....*....|...
gi 2024460663 491 SVPfEGVISDDSSIRIDFLAEEPAASTAFNIRF 523
Cdd:pfam00431 79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
|
|
| CCP |
cd00033 |
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ... |
357-412 |
2.52e-07 |
|
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Pssm-ID: 153056 [Multi-domain] Cd Length: 57 Bit Score: 48.23 E-value: 2.52e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460663 357 CSFPRRPDFGDVTVM--DLHSGGIAHFHCHLGYELQGPHMLTCInaSRPHWSSPEPIC 412
Cdd:cd00033 1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCT--ENGGWSPPPPTC 56
|
|
| CCP |
smart00032 |
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ... |
357-412 |
6.71e-07 |
|
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
Pssm-ID: 214478 [Multi-domain] Cd Length: 56 Bit Score: 47.14 E-value: 6.71e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460663 357 CSFPRRPDFGDVTVM--DLHSGGIAHFHCHLGYELQGPHMLTCINASrpHWSSPEPIC 412
Cdd:smart00032 1 CPPPPDIENGTVTSSsgTYSYGDTVTYSCDPGYTLIGSSTITCLENG--TWSPPPPTC 56
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
18-189 |
8.62e-07 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 52.85 E-value: 8.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 18 PAAPRPDGRPEaaplPASPRPLPADEASMGGPRQGAALNlLPAAEDSPKPAVEGPSLRAQSHiSPAPTTDPGADTK---- 93
Cdd:NF033839 292 PSAPKPGMQPS----PQPEKKEVKPEPETPKPEVKPQLE-KPKPEVKPQPEKPKPEVKPQLE-TPKPEVKPQPEKPkpev 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 94 QTFPAKKKPPALKHSNTARKQLKAKPTLPGLSRAVSTQgSVLPVSSQEPSIPMETADGQRQSP-PELPGWGPTSRPLLQI 172
Cdd:NF033839 366 KPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPE-KPKPEVKPQPEKPKPEVKPQPEKPkPEVKPQPEKPKPEVKP 444
|
170
....*....|....*..
gi 2024460663 173 SPFTPVPSTaQPFPGGP 189
Cdd:NF033839 445 QPEKPKPEV-KPQPETP 460
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
426-483 |
1.73e-05 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 44.69 E-value: 1.73e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024460663 426 GRVLSPSTAGNQSGSMYCVWAITAPPGQKLHLHFEKLLLAER-----DRMVVYSGDSNRSAVL 483
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLL 63
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
17-270 |
9.29e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.68 E-value: 9.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 17 SPAAPRPDGRPEAAPLPASPR----------PLPADEASMGGP----RQGAALNllPAAEDSPKPAVEG-PSLRAQSHIS 81
Cdd:pfam03154 185 SPPPPGTTQAATAGPTPSAPSvppqgspatsQPPNQTQSTAAPhtliQQTPTLH--PQRLPSPHPPLQPmTQPPPPSQVS 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 82 PAPTTDP---GADTKQTFPAKKKPPALKHSNtarkqlkakPTLPGLSRAVSTQGSVLPV--------SSQEPSIPMETAD 150
Cdd:pfam03154 263 PQPLPQPslhGQMPPMPHSLQTGPSHMQHPV---------PPQPFPLTPQSSQSQVPPGpspaapgqSQQRIHTPPSQSQ 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 151 GQRQSPPE---LPGwGPTSRPLLQISPFTPVPSTAQP-------FPGGPGDVGTGPTAAPSGAINQMDSAESEMNGSAS- 219
Cdd:pfam03154 334 LQSQQPPReqpLPP-APLSMPHIKPPPTTPIPQLPNPqshkhppHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHp 412
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460663 220 ------EESQETTTSTIITTTVITTEPTPVRCSvSFYDPEGYIDSTDYPPLPRHSFL 270
Cdd:pfam03154 413 pplqlmPQSQQLPPPPAQPPVLTQSQSLPPPAA-SHPPTSGLHQVPSQSPFPQHPFV 468
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
18-203 |
2.63e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 44.67 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 18 PAAPRPDGRPeaAPLPASPRPLPADEASMGGPRQG-----AALNLLPAAEDSPKPAVEGPSLRAQSHI-----SPAPTTD 87
Cdd:COG5180 237 PSTSEARSRP--ATVDAQPEMRPPADAKERRRAAIgdtpaAEPPGLPVLEAGSEPQSDAPEAETARPIdvkgvASAPPAT 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 88 -----PGADTKQTFPAKK-----------------KPPAlkHSNTARkqlKAKPTLPGLSRAVSTQGSVLPVssqEPSIP 145
Cdd:COG5180 315 rpvrpPGGARDPGTPRPGqpterpagvpeaasdagQPPS--AYPPAE---EAVPGKPLEQGAPRPGSSGGDG---APFQP 386
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024460663 146 METADGQRQSPPELPGWGPTSRPLLQISPFTPVPSTAQPFP-----GGPGDVGTGPTAAPSGA 203
Cdd:COG5180 387 PNGAPQPGLGRRGAPGPPMGAGDLVQAALDGGGRETASLGGaaggaGQGPKADFVPGDAESVS 449
|
|
| Sushi |
pfam00084 |
Sushi repeat (SCR repeat); |
357-412 |
3.27e-04 |
|
Sushi repeat (SCR repeat);
Pssm-ID: 459664 [Multi-domain] Cd Length: 56 Bit Score: 39.40 E-value: 3.27e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460663 357 CSFPRRPDFGDVTV-MDLHS-GGIAHFHCHLGYELQGPHMLTCINASRphWSSPEPIC 412
Cdd:pfam00084 1 CPPPPDIPNGKVSAtKNEYNyGASVSYECDPGYRLVGSPTITCQEDGT--WSPPFPEC 56
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
254-350 |
2.62e-03 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 38.14 E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 254 GYIDSTDYPpLPRHSFLECTYNVTVYTGYGVELQVKSVNLSDGE-----VLSIRGVDDDTLVVLANQT-LLVEGQVIRSP 327
Cdd:smart00042 1 GTITSPNYP-QSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceydYVEIYDGPSASSPLLGRFCgSEAPPPVISSS 79
|
90 100
....*....|....*....|...
gi 2024460663 328 TNTISVYFRTFQDEAVGTFQLHY 350
Cdd:smart00042 80 SNSLTLTFVSDSSVQKRGFSARY 102
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
592-700 |
8.36e-26 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 102.88 E-value: 8.36e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 592 CGGELTAMA-GVILSPNWPEPYTEGEDCIWRVHVGEEKRLFLDIQLLNLTNS-----DILTIYDGDELSARILGQYVGSS 665
Cdd:cd00041 1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80
|
90 100 110
....*....|....*....|....*....|....*
gi 2024460663 666 GPQKLYSSSPDLTIRFHSDPAglifGKGQGFIMNY 700
Cdd:cd00041 81 LPPPIISSGNSLTVRFRSDSS----VTGRGFKATY 111
|
|
| CUB |
pfam00431 |
CUB domain; |
592-687 |
1.01e-20 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 88.12 E-value: 1.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 592 CGGELTAMAGVILSPNWPEPYTEGEDCIWRVHVGEEKRLFLDIQLLNLTNS-----DILTIYDGDELSARILGQYVGSSG 666
Cdd:pfam00431 1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHdecgyDYVEIRDGPSASSPLLGRFCGSGI 80
|
90 100
....*....|....*....|.
gi 2024460663 667 PQKLYSSSPDLTIRFHSDPAG 687
Cdd:pfam00431 81 PEDIVSSSNQMTIKFVSDASV 101
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
601-700 |
5.66e-18 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 80.13 E-value: 5.66e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 601 GVILSPNWPEPYTEGEDCIWRVHVGEEKRLFLDIQLLNLTNS-----DILTIYDGDELSARILGQYVGSSGPQKLYSS-S 674
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSsS 80
|
90 100
....*....|....*....|....*.
gi 2024460663 675 PDLTIRFHSDPAglifGKGQGFIMNY 700
Cdd:smart00042 81 NSLTLTFVSDSS----VQKRGFSARY 102
|
|
| PHA02927 |
PHA02927 |
secreted complement-binding protein; Provisional |
709-894 |
1.08e-13 |
|
secreted complement-binding protein; Provisional
Pssm-ID: 222943 [Multi-domain] Cd Length: 263 Bit Score: 72.38 E-value: 1.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 709 CSDLPEIQNGWKTTSHTELvrGAKITYQCDPGYDIVGSDTLTCQW----DLSWSSDPPFCEKIMyCTDPGEVEHSTRLIS 784
Cdd:PHA02927 86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESVK-CQSPPSISNGRHNGY 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 785 DPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPiwtsrlPHCvseESLACDNPGLpENGY-QILYKRLYLPGESLTF 863
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDP------PTC---QIVKCPHPTI-SNGYlSSGFKRSYSYNDNVDF 232
|
170 180 190
....*....|....*....|....*....|.
gi 2024460663 864 MCYEGFELMGEVTIKCILGqpSHWSGPLPIC 894
Cdd:PHA02927 233 KCKYGYKLSGSSSSTCSPG--NTWQPELPKC 261
|
|
| CCP |
cd00033 |
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ... |
709-765 |
3.20e-13 |
|
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Pssm-ID: 153056 [Multi-domain] Cd Length: 57 Bit Score: 65.18 E-value: 3.20e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460663 709 CSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 765
Cdd:cd00033 1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
|
|
| CCP |
smart00032 |
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ... |
709-764 |
3.96e-13 |
|
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
Pssm-ID: 214478 [Multi-domain] Cd Length: 56 Bit Score: 64.86 E-value: 3.96e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460663 709 CSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 764
Cdd:smart00032 1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
|
|
| PHA02927 |
PHA02927 |
secreted complement-binding protein; Provisional |
708-896 |
5.26e-13 |
|
secreted complement-binding protein; Provisional
Pssm-ID: 222943 [Multi-domain] Cd Length: 263 Bit Score: 70.45 E-value: 5.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 708 SCSDLP------EIQNGWKTTSHTELVRGAKITYQCDPGY--DIVGSDTLTCQ---WDLswssdppFCEKIMY-CTDPGE 775
Cdd:PHA02927 19 SCCTIPsrpinmKFKNSVETDANANYNIGDTIEYLCLPGYrkQKMGPIYAKCTgtgWTL-------FNQCIKRrCPSPRD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 776 VEHSTRLISDpvLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCvseESLACDNPGLPENGYQILYKRLY 855
Cdd:PHA02927 92 IDNGQLDIGG--VDFGSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPIC---ESVKCQSPPSISNGRHNGYEDFY 166
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2024460663 856 LPGESLTFMCYEGFELMGEVTIKCILGQpshWSGPlPICKV 896
Cdd:PHA02927 167 TDGSVVTYSCNSGYSLIGNSGVLCSGGE---WSDP-PTCQI 203
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
416-525 |
2.59e-12 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 64.36 E-value: 2.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 416 CGGTVHNATIGRVLSPSTAGNQSGSMYCVWAITAPPGQKLHLHFEKLLLAE-----RDRMVVYSGDSNRSAVLyDSLRAD 490
Cdd:cd00041 1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESspncsYDYLEIYDGPSTSSPLL-GRFCGS 79
|
90 100 110
....*....|....*....|....*....|....*
gi 2024460663 491 SVPFEgVISDDSSIRIDFLAEEPAASTAFNIRFEA 525
Cdd:cd00041 80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| Sushi |
pfam00084 |
Sushi repeat (SCR repeat); |
709-764 |
4.21e-12 |
|
Sushi repeat (SCR repeat);
Pssm-ID: 459664 [Multi-domain] Cd Length: 56 Bit Score: 61.75 E-value: 4.21e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460663 709 CSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 764
Cdd:pfam00084 1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
|
|
| CCP |
cd00033 |
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ... |
837-895 |
1.09e-11 |
|
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Pssm-ID: 153056 [Multi-domain] Cd Length: 57 Bit Score: 60.55 E-value: 1.09e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460663 837 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIKCILGqpSHWSGPLPICK 895
Cdd:cd00033 1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
|
|
| CCP |
smart00032 |
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ... |
837-894 |
6.56e-11 |
|
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
Pssm-ID: 214478 [Multi-domain] Cd Length: 56 Bit Score: 58.31 E-value: 6.56e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460663 837 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIKCILGqpSHWSGPLPIC 894
Cdd:smart00032 1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN--GTWSPPPPTC 56
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
20-199 |
9.90e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.50 E-value: 9.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 20 APRPDG--------RPEAAPLPASPRpLPADEAsmGGPRQGAALNLLPAAEDSPKPAVEGPSLRAQSHISPAPTTDPGAD 91
Cdd:PHA03247 2574 APRPSEpavtsrarRPDAPPQSARPR-APVDDR--GDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPE 2650
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 92 TKQTFPAkkkPPALKHSNTARKQLKA--------KPTLPGLSRAV-STQGSVLPVSSQEPSIPMETADGQRQSPPELPGW 162
Cdd:PHA03247 2651 RPRDDPA---PGRVSRPRRARRLGRAaqassppqRPRRRAARPTVgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAA 2727
|
170 180 190
....*....|....*....|....*....|....*..
gi 2024460663 163 GPTSRPLLQISPFTPVPSTAQPFPGGPGDVGTGPTAA 199
Cdd:PHA03247 2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTA 2764
|
|
| PHA02639 |
PHA02639 |
EEV host range protein; Provisional |
700-898 |
1.90e-10 |
|
EEV host range protein; Provisional
Pssm-ID: 165022 [Multi-domain] Cd Length: 295 Bit Score: 63.14 E-value: 1.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 700 YIEVSRNDSCSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLTCQWDLS---WSSDPPFCeKIMYCTDPGEV 776
Cdd:PHA02639 13 YVHGVKSIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFC-MLKECNDPPSI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 777 EHSTRLISDPVLLVGTTIQYTCNP----GFVLEGSSLLTCYSRETgtpiWTSRLPHCvseESLACDNPGLpENGY--QIL 850
Cdd:PHA02639 92 INGKIYNKREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKS----WKPDPPIC---KMINCRFPAL-QNGYinGIP 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2024460663 851 YKRLYLPGESLTFMCYEGFELMGEVTIKCILGqpSHWSGPLPICKVNQ 898
Cdd:PHA02639 164 SNKKFYYKTRVGFSCKSGFDLVGEKYSTCNIN--ATWFPSIPTCVRNK 209
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1-204 |
7.71e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.42 E-value: 7.71e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 1 MPGPRGLCLLALLLLGSPAAPRPDGRPEAAPLPASPRPLPADEASMGGPRQGA----------------------ALNLL 58
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPpaapaagpprrltrpavaslseSRESL 2798
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 59 PAAEDSPKP--AVEGPSLRAQSHISPAPTTDPGADTKQTFPAKKKPPA---------------LKHSNTARkQLKAKPTL 121
Cdd:PHA03247 2799 PSPWDPADPpaAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPppslplggsvapggdVRRRPPSR-SPAAKPAA 2877
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 122 PGLSRAVSTqgSVLPVSSQEPSIPMETADGQRQSPPELPGW-GPTSRPLLQISPFTPVPSTAQPFPGGPGDVGTGPTAAP 200
Cdd:PHA03247 2878 PARPPVRRL--ARPAVSRSTESFALPPDQPERPPQPQAPPPpQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEP 2955
|
....
gi 2024460663 201 SGAI 204
Cdd:PHA03247 2956 SGAV 2959
|
|
| PHA02639 |
PHA02639 |
EEV host range protein; Provisional |
709-835 |
1.47e-09 |
|
EEV host range protein; Provisional
Pssm-ID: 165022 [Multi-domain] Cd Length: 295 Bit Score: 60.45 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 709 CSDLPEIQNGwKTTSHTELVR-GAKITYQCDP----GYDIVGSDTLTCQWDLSWSSDPPFCeKIMYCTDPG-EVEHSTRL 782
Cdd:PHA02639 85 CNDPPSIING-KIYNKREMYKvGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKPDPPIC-KMINCRFPAlQNGYINGI 162
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2024460663 783 ISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETgtpiWTSRLPHCVSEESL 835
Cdd:PHA02639 163 PSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINAT----WFPSIPTCVRNKPI 211
|
|
| PHA02817 |
PHA02817 |
EEV Host range protein; Provisional |
707-830 |
1.86e-09 |
|
EEV Host range protein; Provisional
Pssm-ID: 165167 [Multi-domain] Cd Length: 225 Bit Score: 59.18 E-value: 1.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 707 DSCSDLPEIQNGWKTTSHTELVRGAKITYQCDPG-----YDIVGSDTLTCQWDLSWSSDPPFCEkIMYCTDPG-EVEHST 780
Cdd:PHA02817 22 NKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCK-IIRCRFPAlQNGFVN 100
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2024460663 781 RLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETgtpiWTSRLPHCV 830
Cdd:PHA02817 101 GIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSS----WIPKVPICS 146
|
|
| CCP |
cd00033 |
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ... |
770-830 |
3.35e-09 |
|
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Pssm-ID: 153056 [Multi-domain] Cd Length: 57 Bit Score: 53.62 E-value: 3.35e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024460663 770 CTDPGEVEHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCysreTGTPIWTSRLPHCV 830
Cdd:cd00033 1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITC----TENGGWSPPPPTCE 57
|
|
| CCP |
smart00032 |
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ... |
770-829 |
3.99e-09 |
|
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
Pssm-ID: 214478 [Multi-domain] Cd Length: 56 Bit Score: 53.30 E-value: 3.99e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 770 CTDPGEVEHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCysRETGTpiWTSRLPHC 829
Cdd:smart00032 1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITC--LENGT--WSPPPPTC 56
|
|
| Sushi |
pfam00084 |
Sushi repeat (SCR repeat); |
531-588 |
7.32e-09 |
|
Sushi repeat (SCR repeat);
Pssm-ID: 459664 [Multi-domain] Cd Length: 56 Bit Score: 52.50 E-value: 7.32e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460663 531 CYEP-YIQNGNFTTSDPTYNLGTTVEFTCDPGHSLeQGPAVIECVNmrDPYWNDTEPLC 588
Cdd:pfam00084 1 CPPPpDIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
|
|
| PHA02927 |
PHA02927 |
secreted complement-binding protein; Provisional |
709-830 |
9.92e-09 |
|
secreted complement-binding protein; Provisional
Pssm-ID: 222943 [Multi-domain] Cd Length: 263 Bit Score: 57.36 E-value: 9.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 709 CSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLTC---QWdlswsSDPPFCEkIMYCTDPGevehstrlISD 785
Cdd:PHA02927 148 CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCsggEW-----SDPPTCQ-IVKCPHPT--------ISN 213
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2024460663 786 PVLLVG--------TTIQYTCNPGFVLEGSSLLTCYSRETgtpiWTSRLPHCV 830
Cdd:PHA02927 214 GYLSSGfkrsysynDNVDFKCKYGYKLSGSSSSTCSPGNT----WQPELPKCV 262
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-220 |
1.46e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 59.18 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 4 PRGLCLLALLLLGSPAAPRPDGRPEAAPLPASPRPLPADEASM-GGPRQGAALNLLPAAEDSPKPAVEGPS-----LRAQ 77
Cdd:PHA03247 255 PAPPPVVGEGADRAPETARGATGPPPPPEAAAPNGAAAPPDGVwGAALAGAPLALPAPPDPPPPAPAGDAEeeddeDGAM 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 78 SHISPAPTtdPGADTKQTFPAKKKP----PALKHSNTARKQLKAKPTLPGLSRAvSTQGSVLPVSSQEPsipmetADGQR 153
Cdd:PHA03247 335 EVVSPLPR--PRQHYPLGFPKRRRPtwtpPSSLEDLSAGRHHPKRASLPTRKRR-SARHAATPFARGPG------GDDQT 405
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460663 154 QSPPELPGWGPTSRPLLQISPFTPVPSTAQPFPGGPGDVGTGPTAAPSGAINQMDSAESEMNGSASE 220
Cdd:PHA03247 406 RPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPERQPPAPATEPAPDDPDDATRK 472
|
|
| PHA02831 |
PHA02831 |
EEV host range protein; Provisional |
708-833 |
2.34e-08 |
|
EEV host range protein; Provisional
Pssm-ID: 165176 [Multi-domain] Cd Length: 268 Bit Score: 56.54 E-value: 2.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 708 SCSDLPEIQNGWKTTSHTELVRGAKITYQCDPG----YDIVGSDTLTCqWDLSWSSDPPFCeKIMYCTDPGeVEHSTRLI 783
Cdd:PHA02831 77 NCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNklekYSIVGNETVKC-INKQWVPKYPVC-KLIRCKYPA-LQNGFLNV 153
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2024460663 784 SDPVLLVGTTIQYTCNPGFVLEGSSLLTCysreTGTPIWTSRLPHCVSEE 833
Cdd:PHA02831 154 FEKKFYYGDIVNFKCKKGFILLGSSVSTC----DINSIWYPGIPKCVKDK 199
|
|
| CCP |
cd00033 |
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ... |
531-589 |
3.55e-08 |
|
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Pssm-ID: 153056 [Multi-domain] Cd Length: 57 Bit Score: 50.92 E-value: 3.55e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 531 CYEPY-IQNGNFTTSDPTYNLGTTVEFTCDPGHSLeQGPAVIECvnMRDPYWNDTEPLCR 589
Cdd:cd00033 1 CPPPPvPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITC--TENGGWSPPPPTCE 57
|
|
| CCP |
smart00032 |
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ... |
534-588 |
3.95e-08 |
|
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
Pssm-ID: 214478 [Multi-domain] Cd Length: 56 Bit Score: 50.60 E-value: 3.95e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 2024460663 534 PYIQNGNFTTSDPTYNLGTTVEFTCDPGHSLeQGPAVIECVNmrDPYWNDTEPLC 588
Cdd:smart00032 5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITCLE--NGTWSPPPPTC 56
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
18-204 |
4.75e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 57.64 E-value: 4.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 18 PAAPRPDGRPEAAPLPASPRPlPADEASMGGPR--------QGAALNLLPAAEDSPKP--AVEGPSLRAQSHISPAPTTD 87
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAPAP-PAAPAAGPPRRltrpavasLSESRESLPSPWDPADPpaAVLAPAAALPPAASPAGPLP 2829
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 88 PGADTKQTFPAKKKPPA---------------LKHSNTARkQLKAKPTLPG------LSR-AVSTQGSVLPVSSQEPSIP 145
Cdd:PHA03247 2830 PPTSAQPTAPPPPPGPPppslplggsvapggdVRRRPPSR-SPAAKPAAPArppvrrLARpAVSRSTESFALPPDQPERP 2908
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460663 146 METADGQRQSPPELPGWGPTSRPLLQISPFTPVPSTAQPFPGGPGDVGTGPTAAPSGAI 204
Cdd:PHA03247 2909 PQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL 2967
|
|
| CUB |
pfam00431 |
CUB domain; |
416-523 |
1.82e-07 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 50.37 E-value: 1.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 416 CGGTVHNATiGRVLSPSTAGNQSGSMYCVWAITAPPGQKLHLHFEKLLLAERDR-----MVVYSGDSnRSAVLYDSLRAD 490
Cdd:pfam00431 1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDEcgydyVEIRDGPS-ASSPLLGRFCGS 78
|
90 100 110
....*....|....*....|....*....|...
gi 2024460663 491 SVPfEGVISDDSSIRIDFLAEEPAASTAFNIRF 523
Cdd:pfam00431 79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
|
|
| Sushi |
pfam00084 |
Sushi repeat (SCR repeat); |
770-829 |
2.03e-07 |
|
Sushi repeat (SCR repeat);
Pssm-ID: 459664 [Multi-domain] Cd Length: 56 Bit Score: 48.65 E-value: 2.03e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 770 CTDPGEVEHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCysRETGTpiWTSRLPHC 829
Cdd:pfam00084 1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITC--QEDGT--WSPPFPEC 56
|
|
| CCP |
cd00033 |
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ... |
357-412 |
2.52e-07 |
|
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Pssm-ID: 153056 [Multi-domain] Cd Length: 57 Bit Score: 48.23 E-value: 2.52e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460663 357 CSFPRRPDFGDVTVM--DLHSGGIAHFHCHLGYELQGPHMLTCInaSRPHWSSPEPIC 412
Cdd:cd00033 1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCT--ENGGWSPPPPTC 56
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2-224 |
2.81e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 54.61 E-value: 2.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 2 PGPRGLCLLALLLLGSPAAPRPDGRPEAAPLPASP-RPLPADEASMGGPRQGAALNLLPAAEDSPKPAVE-----GPSLR 75
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPaAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVpdasdGGDGW 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 76 AQSHISPAPTTDPGADTKQTFPAKKKPPAlkhsntarKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETADGQRQS 155
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAP--------AQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPL 741
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460663 156 PPElPGWGPTSRPLLQISPFTPVPSTAQPfPGGPGDVGTGPTAAPSgainqMDSAESEMNGSASEESQE 224
Cdd:PRK07764 742 PPE-PDDPPDPAGAPAQPPPPPAPAPAAA-PAAAPPPSPPSEEEEM-----AEDDAPSMDDEDRRDAEE 803
|
|
| Sushi |
pfam00084 |
Sushi repeat (SCR repeat); |
837-894 |
5.25e-07 |
|
Sushi repeat (SCR repeat);
Pssm-ID: 459664 [Multi-domain] Cd Length: 56 Bit Score: 47.49 E-value: 5.25e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024460663 837 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIKCIL-GQpshWSGPLPIC 894
Cdd:pfam00084 1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGT---WSPPFPEC 56
|
|
| CCP |
smart00032 |
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ... |
357-412 |
6.71e-07 |
|
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.
Pssm-ID: 214478 [Multi-domain] Cd Length: 56 Bit Score: 47.14 E-value: 6.71e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460663 357 CSFPRRPDFGDVTVM--DLHSGGIAHFHCHLGYELQGPHMLTCINASrpHWSSPEPIC 412
Cdd:smart00032 1 CPPPPDIENGTVTSSsgTYSYGDTVTYSCDPGYTLIGSSTITCLENG--TWSPPPPTC 56
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
18-189 |
8.62e-07 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 52.85 E-value: 8.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 18 PAAPRPDGRPEaaplPASPRPLPADEASMGGPRQGAALNlLPAAEDSPKPAVEGPSLRAQSHiSPAPTTDPGADTK---- 93
Cdd:NF033839 292 PSAPKPGMQPS----PQPEKKEVKPEPETPKPEVKPQLE-KPKPEVKPQPEKPKPEVKPQLE-TPKPEVKPQPEKPkpev 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 94 QTFPAKKKPPALKHSNTARKQLKAKPTLPGLSRAVSTQgSVLPVSSQEPSIPMETADGQRQSP-PELPGWGPTSRPLLQI 172
Cdd:NF033839 366 KPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPE-KPKPEVKPQPEKPKPEVKPQPEKPkPEVKPQPEKPKPEVKP 444
|
170
....*....|....*..
gi 2024460663 173 SPFTPVPSTaQPFPGGP 189
Cdd:NF033839 445 QPEKPKPEV-KPQPETP 460
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
17-205 |
2.17e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.25 E-value: 2.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 17 SPAAPRPDGRPEAAPLPASPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEGPSLRAQSHISPA------------- 83
Cdd:PHA03247 2608 PRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAqassppqrprrra 2687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 84 --PTTDPGADTKQTFPAKKKP-----------PALKHSNTARKQLKAKPTLPgLSRAVSTqGSVLPVSSQEPSIPMETAD 150
Cdd:PHA03247 2688 arPTVGSLTSLADPPPPPPTPepaphalvsatPLPPGPAAARQASPALPAAP-APPAVPA-GPATPGGPARPARPPTTAG 2765
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2024460663 151 GQRQSPPELPGWGPTSRPLLQISPFTPVPSTAQPFPGGPGDVgTGPTAAPSGAIN 205
Cdd:PHA03247 2766 PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP-PAAVLAPAAALP 2819
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
18-204 |
3.61e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 51.48 E-value: 3.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 18 PAAPRPDG-RPEAAPLPASPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEGPSLraqSHISPAPTTDPGADTKQTF 96
Cdd:PHA03247 2680 PQRPRRRAaRPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPA---APAPPAVPAGPATPGGPAR 2756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 97 PAKKKPPALKHSNTArkqlKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETADGQRQSPPELPGWGPTSRPllqiSPFT 176
Cdd:PHA03247 2757 PARPPTTAGPPAPAP----PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASP----AGPL 2828
|
170 180
....*....|....*....|....*...
gi 2024460663 177 PVPSTAQPFPGGPGDVGTGPTAAPSGAI 204
Cdd:PHA03247 2829 PPPTSAQPTAPPPPPGPPPPSLPLGGSV 2856
|
|
| PHA02954 |
PHA02954 |
EEV membrane glycoprotein; Provisional |
730-830 |
5.55e-06 |
|
EEV membrane glycoprotein; Provisional
Pssm-ID: 165263 [Multi-domain] Cd Length: 317 Bit Score: 49.70 E-value: 5.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 730 GAKITYQCDPGYDIVGSDTLTCQWDlSWSSDPPFCEKimyCTDPgevEHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSL 809
Cdd:PHA02954 150 GEHITINCDVGYEVIGASYISCTAN-SWNVIPSCQQK---CDIP---SLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPS 222
|
90 100
....*....|....*....|.
gi 2024460663 810 LTCYSREtgtpiWTSRLPHCV 830
Cdd:PHA02954 223 STCIDGK-----WNPVLPICV 238
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
19-189 |
8.11e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 50.32 E-value: 8.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 19 AAPRPDGR-PEAAPLPASPR-PLPAdeasmgGPRQGAALNLLPAAEDSPKPAVEGPSLRA--QSHISPAPTTDPGADTKQ 94
Cdd:PHA03247 2699 ADPPPPPPtPEPAPHALVSAtPLPP------GPAAARQASPALPAAPAPPAVPAGPATPGgpARPARPPTTAGPPAPAPP 2772
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 95 TFPAKKKPPALkhsnTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETADGQRQSPPELPgwGPTSRPLLQISP 174
Cdd:PHA03247 2773 AAPAAGPPRRL----TRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSA--QPTAPPPPPGPP 2846
|
170
....*....|....*
gi 2024460663 175 FTPVPSTAQPFPGGP 189
Cdd:PHA03247 2847 PPSLPLGGSVAPGGD 2861
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
426-483 |
1.73e-05 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 44.69 E-value: 1.73e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024460663 426 GRVLSPSTAGNQSGSMYCVWAITAPPGQKLHLHFEKLLLAER-----DRMVVYSGDSNRSAVL 483
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLL 63
|
|
| PHA02831 |
PHA02831 |
EEV host range protein; Provisional |
732-894 |
3.76e-05 |
|
EEV host range protein; Provisional
Pssm-ID: 165176 [Multi-domain] Cd Length: 268 Bit Score: 46.52 E-value: 3.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 732 KITYQCDPGYDIVgsdTLTCQwDLSWSSDPpFCEKIMYCTDP-----GEVEHSTRLISdpvllVGTTIQYTCNPG----F 802
Cdd:PHA02831 45 NLEYKCNNNFDKV---FVTCN-NGSWSTKN-MCIGKRNCKDPvtilnGYIKNKKDQYS-----FGDSVTYACKVNklekY 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 803 VLEGSSLLTCYSREtgtpiWTSRLPHCvseESLACDNPGLpENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIKCilG 882
Cdd:PHA02831 115 SIVGNETVKCINKQ-----WVPKYPVC---KLIRCKYPAL-QNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTC--D 183
|
170
....*....|..
gi 2024460663 883 QPSHWSGPLPIC 894
Cdd:PHA02831 184 INSIWYPGIPKC 195
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
17-270 |
9.29e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.68 E-value: 9.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 17 SPAAPRPDGRPEAAPLPASPR----------PLPADEASMGGP----RQGAALNllPAAEDSPKPAVEG-PSLRAQSHIS 81
Cdd:pfam03154 185 SPPPPGTTQAATAGPTPSAPSvppqgspatsQPPNQTQSTAAPhtliQQTPTLH--PQRLPSPHPPLQPmTQPPPPSQVS 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 82 PAPTTDP---GADTKQTFPAKKKPPALKHSNtarkqlkakPTLPGLSRAVSTQGSVLPV--------SSQEPSIPMETAD 150
Cdd:pfam03154 263 PQPLPQPslhGQMPPMPHSLQTGPSHMQHPV---------PPQPFPLTPQSSQSQVPPGpspaapgqSQQRIHTPPSQSQ 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 151 GQRQSPPE---LPGwGPTSRPLLQISPFTPVPSTAQP-------FPGGPGDVGTGPTAAPSGAINQMDSAESEMNGSAS- 219
Cdd:pfam03154 334 LQSQQPPReqpLPP-APLSMPHIKPPPTTPIPQLPNPqshkhppHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHp 412
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460663 220 ------EESQETTTSTIITTTVITTEPTPVRCSvSFYDPEGYIDSTDYPPLPRHSFL 270
Cdd:pfam03154 413 pplqlmPQSQQLPPPPAQPPVLTQSQSLPPPAA-SHPPTSGLHQVPSQSPFPQHPFV 468
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
19-200 |
9.56e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 46.41 E-value: 9.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 19 AAPRPDGRPEA-APLPASPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEG-PSLRAQSHISPAPTTDPgADTKQTF 96
Cdd:PRK12323 379 AAPVAQPAPAAaAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEAlAAARQASARGPGGAPAP-APAPAAA 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 97 PAKKKPPALKHSNTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPsiPMETADGQRQSPPELPGWGPTSrpllqispfT 176
Cdd:PRK12323 458 PAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELP--PEFASPAPAQPDAAPAGWVAES---------I 526
|
170 180
....*....|....*....|....
gi 2024460663 177 PVPSTAQPFPGGPGDVgTGPTAAP 200
Cdd:PRK12323 527 PDPATADPDDAFETLA-PAPAAAP 549
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
16-215 |
1.10e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 46.32 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 16 GSPAAPRPDGRPEAAPLPASPRPLPADEASMGGPRQGAalnllPAAEDSPKPAVEGPSlraqshisPAPTTDPGADTKQT 95
Cdd:PHA03307 73 PGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPG-----PSSPDPPPPTPPPAS--------PPPSPAPDLSEMLR 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 96 FPAKKKPPALKHSNTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETAdgqrqsPPELPGWGPTSRPLLQISPF 175
Cdd:PHA03307 140 PVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEP------PPSTPPAAASPRPPRRSSPI 213
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2024460663 176 TPVPSTAQPFPGGPGDVGTGPTAAPSGAINQMDSAESEMN 215
Cdd:PHA03307 214 SASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPEN 253
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
16-199 |
1.43e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 46.00 E-value: 1.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 16 GSPAAPRPDGRPEAAPLPAsPRPLPADEASMGGPRqgAALNLLPAAEDSPKPAVEGPSLRAQShisPAPTTDPGADTKQT 95
Cdd:PRK07003 366 GAPGGGVPARVAGAVPAPG-ARAAAAVGASAVPAV--TAVTGAAGAALAPKAAAAAAATRAEA---PPAAPAPPATADRG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 96 FPAKKKPPALKHSNTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETADGQRQSPPELPGWGPTSRPLLQIS-- 173
Cdd:PRK07003 440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASre 519
|
170 180 190
....*....|....*....|....*....|...
gi 2024460663 174 -----PFTPVPSTAQPFPGG--PGDVGTGPTAA 199
Cdd:PRK07003 520 dapaaAAPPAPEARPPTPAAaaPAARAGGAAAA 552
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
35-189 |
2.53e-04 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 45.07 E-value: 2.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 35 SPRPLPA----DEASMGGPRQGAALNLLPAAEDSPKPAVEGPSLRAQSHISPAPTTDPGaDTKQTFPAKKKPPALKHSNT 110
Cdd:PTZ00449 492 SKKKLAPieeeDSDKHDEPPEGPEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPG-ETKEGEVGKKPGPAKEHKPS 570
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 111 ARKQLKAKPTLPGLS----RAVSTQGSVLPVSSQEPSIPMETADGQRQSPPELPgwgptSRPLLQISPFTPVPSTAQPFP 186
Cdd:PTZ00449 571 KIPTLSKKPEFPKDPkhpkDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSP-----KRPESPKSPKRPPPPQRPSSP 645
|
...
gi 2024460663 187 GGP 189
Cdd:PTZ00449 646 ERP 648
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
18-203 |
2.63e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 44.67 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 18 PAAPRPDGRPeaAPLPASPRPLPADEASMGGPRQG-----AALNLLPAAEDSPKPAVEGPSLRAQSHI-----SPAPTTD 87
Cdd:COG5180 237 PSTSEARSRP--ATVDAQPEMRPPADAKERRRAAIgdtpaAEPPGLPVLEAGSEPQSDAPEAETARPIdvkgvASAPPAT 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 88 -----PGADTKQTFPAKK-----------------KPPAlkHSNTARkqlKAKPTLPGLSRAVSTQGSVLPVssqEPSIP 145
Cdd:COG5180 315 rpvrpPGGARDPGTPRPGqpterpagvpeaasdagQPPS--AYPPAE---EAVPGKPLEQGAPRPGSSGGDG---APFQP 386
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024460663 146 METADGQRQSPPELPGWGPTSRPLLQISPFTPVPSTAQPFP-----GGPGDVGTGPTAAPSGA 203
Cdd:COG5180 387 PNGAPQPGLGRRGAPGPPMGAGDLVQAALDGGGRETASLGGaaggaGQGPKADFVPGDAESVS 449
|
|
| Sushi |
pfam00084 |
Sushi repeat (SCR repeat); |
357-412 |
3.27e-04 |
|
Sushi repeat (SCR repeat);
Pssm-ID: 459664 [Multi-domain] Cd Length: 56 Bit Score: 39.40 E-value: 3.27e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024460663 357 CSFPRRPDFGDVTV-MDLHS-GGIAHFHCHLGYELQGPHMLTCINASRphWSSPEPIC 412
Cdd:pfam00084 1 CPPPPDIPNGKVSAtKNEYNyGASVSYECDPGYRLVGSPTITCQEDGT--WSPPFPEC 56
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-189 |
3.32e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.93 E-value: 3.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 4 PRGLCLLALLLLGSPAAPRPDGRPEAAPLPASP----------------RPLPADEAsmGGPRQGAALNLLPAAED---- 63
Cdd:PHA03247 2492 AGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPvgepvhprmltwirglEELASDDA--GDPPPPLPPAAPPAAPDrsvp 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 64 --SPKPAVEGPSLRAQSH---ISPAPTT-----DPGADTKQTFPAKKKPPAlkhsnTARkqlkAKPTLPGLSRAVSTQGS 133
Cdd:PHA03247 2570 ppRPAPRPSEPAVTSRARrpdAPPQSARprapvDDRGDPRGPAPPSPLPPD-----THA----PDPPPPSPSPAANEPDP 2640
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460663 134 VLPVSSQEPSIPMETADGQRQSPPE--------LPGWGPTSRPLLQISPFT--PVPSTAQPFPGGP 189
Cdd:PHA03247 2641 HPPPTVPPPERPRDDPAPGRVSRPRrarrlgraAQASSPPQRPRRRAARPTvgSLTSLADPPPPPP 2706
|
|
| PHA03264 |
PHA03264 |
envelope glycoprotein D; Provisional |
16-92 |
4.39e-04 |
|
envelope glycoprotein D; Provisional
Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 43.84 E-value: 4.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 16 GSPAaPRPDGRPEAAPLPASPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEG-----------PSLRAQSHISPAP 84
Cdd:PHA03264 273 GSPA-PPGDDRPEAKPEPGPVEDGAPGRETGGEGEGPEPAGRDGAAGGEPKPGPPRpapdadrpegwPSLEAITFPPPTP 351
|
....*...
gi 2024460663 85 TTdPGADT 92
Cdd:PHA03264 352 AT-PAVPR 358
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
17-212 |
9.43e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 43.30 E-value: 9.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 17 SPAAPRPDGRPEAAPLpASPRPLPADEASMGGPRQGAAlnllPAAEDSPKPAVEGP-SLRAQSHISPAPTTDPGADTKQT 95
Cdd:PRK07003 413 KAAAAAAATRAEAPPA-APAPPATADRGDDAADGDAPV----PAKANARASADSRCdERDAQPPADSGSASAPASDAPPD 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 96 FPAKKKPPALKHSNTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETAD-----------------GQRQSPPE 158
Cdd:PRK07003 488 AAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPaaraggaaaaldvlrnaGMRVSSDR 567
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024460663 159 LPGWGPTSRPLLQ--ISPFTPVPSTAQPFPgGPGDVGTGPTAAPSGAINQMDSAES 212
Cdd:PRK07003 568 GARAAAAAKPAAApaAAPKPAAPRVAVQVP-TPRARAATGDAPPNGAARAEQAAES 622
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
18-212 |
1.35e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 42.75 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 18 PAAPRPDGRPEAAPLPASPrplPADEASMGGPRQGAALNLL-PAAEDSPKPAVEGPSLRAQSHIS-----PAPTTDPGAD 91
Cdd:PHA03378 698 PRAPTPMRPPAAPPGRAQR---PAAATGRARPPAAAPGRARpPAAAPGRARPPAAAPGRARPPAAapgraRPPAAAPGAP 774
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 92 T----KQTFPAKKKPPALKHSNTARKQ---------LKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETAdGQRQSPPE 158
Cdd:PHA03378 775 TpqppPQAPPAPQQRPRGAPTPQPPPQagptsmqlmPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAA-LERQAAAG 853
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024460663 159 L---PGWGpTSRPLLQISPFTPVPSTAQPFPGGPGdvgtGPTAAPSGAINQMDSAES 212
Cdd:PHA03378 854 PtpsPGSG-TSDKIVQAPVFYPPVLQPIQVMRQLG----SVRAAAASTVTQAPTEYT 905
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2-189 |
1.83e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.17 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 2 PGPRGLCLLALLLLGSPAAPRPDGRPEAAPLPASPRPLPADEASMGGPRQGAALNLLPAAEDSP--KPAVEGPSLRAQSH 79
Cdd:PRK12323 397 PAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAaaRPAAAGPRPVAAAA 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 80 ISPAPTTDPGADTKqtfPAKKKPPALKhsntarkqlKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETADGQRQSPPEL 159
Cdd:PRK12323 477 AAAPARAAPAAAPA---PADDDPPPWE---------ELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPA 544
|
170 180 190
....*....|....*....|....*....|
gi 2024460663 160 PGWGPTSRPLLQISPFTPVPSTAQPFPGGP 189
Cdd:PRK12323 545 PAAAPAPRAAAATEPVVAPRPPRASASGLP 574
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
2-161 |
1.91e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.14 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 2 PGPRGLCLLALLLLGSPAAPRPDGRPEAAPLP--ASPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEGPSLRAqsh 79
Cdd:PRK07003 381 PAPGARAAAAVGASAVPAVTAVTGAAGAALAPkaAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARA--- 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 80 iSPAPTTDPGADTKQTFPAKKKPPALKHSNTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETADGQRQSPPEL 159
Cdd:PRK07003 458 -SADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPT 536
|
..
gi 2024460663 160 PG 161
Cdd:PRK07003 537 PA 538
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
17-222 |
1.97e-03 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 41.97 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 17 SPAAPRPDGRPEAAPLPASPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEGPSLrAQSHISPAPTTDPGADTkqTF 96
Cdd:COG5180 310 APPATRPVRPPGGARDPGTPRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPGKPL-EQGAPRPGSSGGDGAPF--QP 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 97 PAKKKPPALKHSNT-ARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPmetadGQRQSPPELPGWG--------PTSR 167
Cdd:COG5180 387 PNGAPQPGLGRRGApGPPMGAGDLVQAALDGGGRETASLGGAAGGAGQGP-----KADFVPGDAESVSgpagladqAGAA 461
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2024460663 168 PLLQISPFTPVPSTAQpfPGGPGDVGTGPTAAPSGAINQMDSAESEMNGSASEES 222
Cdd:COG5180 462 ASTAMADFVAPVTDAT--PVDVADVLGVRPDAILGGNVAPASGLDAETRIIEAEG 514
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
20-203 |
2.16e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.79 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 20 APRPDGRP-EAAPLPASPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEGPS---LRAQSHISPAPTTDPGADTKQT 95
Cdd:PRK12323 362 AFRPGQSGgGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAAravAAAPARRSPAPEALAAARQASA 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 96 F-PAKKKPPAlkhSNTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETADGqrqSPP--ELPGWGPTSRPLLQI 172
Cdd:PRK12323 442 RgPGGAPAPA---PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDD---PPPweELPPEFASPAPAQPD 515
|
170 180 190
....*....|....*....|....*....|.
gi 2024460663 173 SPFTPVPSTAQPFPGGPGDVGTGPTAAPSGA 203
Cdd:PRK12323 516 AAPAGWVAESIPDPATADPDDAFETLAPAPA 546
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
20-201 |
2.44e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.76 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 20 APRPDGRPEAAPLPASPRPLPAdeasmggPRQGAAlnllPAAEDSPKPAVEGPSLRAQSHISPAPTTdPGADTKQTFPAK 99
Cdd:PRK07003 361 AVTGGGAPGGGVPARVAGAVPA-------PGARAA----AAVGASAVPAVTAVTGAAGAALAPKAAA-AAAATRAEAPPA 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 100 KKPPALKHSNTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPmETADGQRQSPPELPGWGPTSRPLLQISPFTPVP 179
Cdd:PRK07003 429 APAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADS-GSASAPASDAPPDAAFEPAPRAAAPSAATPAAV 507
|
170 180
....*....|....*....|..
gi 2024460663 180 STAQPFPGGPGDVGTGPTAAPS 201
Cdd:PRK07003 508 PDARAPAAASREDAPAAAAPPA 529
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
254-350 |
2.62e-03 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 38.14 E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 254 GYIDSTDYPpLPRHSFLECTYNVTVYTGYGVELQVKSVNLSDGE-----VLSIRGVDDDTLVVLANQT-LLVEGQVIRSP 327
Cdd:smart00042 1 GTITSPNYP-QSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceydYVEIYDGPSASSPLLGRFCgSEAPPPVISSS 79
|
90 100
....*....|....*....|...
gi 2024460663 328 TNTISVYFRTFQDEAVGTFQLHY 350
Cdd:smart00042 80 SNSLTLTFVSDSSVQKRGFSARY 102
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
24-207 |
2.63e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.68 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 24 DGRPEAAPLPaSPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEGPSLRAQSHISPAPTTDPGADTKQTFPAKKKPP 103
Cdd:pfam03154 140 DNRSTSPSIP-SPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPP 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 104 ALKHSNTARKQLKAKPTLPGLSRAVSTQGSVLPVSSQEPsiPMETAdGQRQSPPELPGWGPTSRPLLQISP-FTPVPSTA 182
Cdd:pfam03154 219 NQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPP--PSQVS-PQPLPQPSLHGQMPPMPHSLQTGPsHMQHPVPP 295
|
170 180
....*....|....*....|....*....
gi 2024460663 183 QPFPGGP----GDVGTGPTAAPSGAINQM 207
Cdd:pfam03154 296 QPFPLTPqssqSQVPPGPSPAAPGQSQQR 324
|
|
| PHA02954 |
PHA02954 |
EEV membrane glycoprotein; Provisional |
708-879 |
3.15e-03 |
|
EEV membrane glycoprotein; Provisional
Pssm-ID: 165263 [Multi-domain] Cd Length: 317 Bit Score: 40.84 E-value: 3.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 708 SCSDLPEIQNGWKTTSHTELVRGAKITYQCDPGYDIVGSDTLtCQWDlSWSSDPPfCEKIMYCTDpgeveHSTRLISDPV 787
Cdd:PHA02954 19 STCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNAV-CETD-KWKYENP-CKKMCTVSD-----YVSELYDKPL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 788 LLVGTTIQYTCNpgfvlEGSSLLTCySRETGTPIWTSRLPhCVSEEslaCDNPGLPENGYQILyKRLYLPGESLTFMCYE 867
Cdd:PHA02954 91 YEVNSTITLICK-----DETKYFRC-EEKNGNTSWNDTVT-CPNAE---CQPLQLEHGSCQPV-KEKYSFGEHITINCDV 159
|
170
....*....|..
gi 2024460663 868 GFELMGEVTIKC 879
Cdd:PHA02954 160 GYEVIGASYISC 171
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
17-168 |
3.18e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 41.11 E-value: 3.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 17 SPAAPRPDGRPEAAPLPASPRPlpaDEASMGGPRQGAALNLLPAAEDSPKPAVEGPSLRAQSHISPAPTTDPGADTKQTF 96
Cdd:PHA03169 130 SPASHSPPPSPPSHPGPHEPAP---PESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQS 206
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024460663 97 PAKKKPPalkhsntarkqlKAKPTLPGLSRAVSTQGSVLPVSSQEPSIPMETADGQRQSPPELPGWGPTSRP 168
Cdd:PHA03169 207 PPDEPGE------------PQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHRSHSYTVVGWKPSTRP 266
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
18-120 |
3.89e-03 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 39.99 E-value: 3.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 18 PAAPRPDGRPEAAPLPASPRPLPADeasmggPRQGAAlnLLPAAEDSPKPAVEgPSLRAQSHISPAPTTDPGADTKQTfP 97
Cdd:PRK11633 42 PLVPKPGDRDEPDMMPAATQALPTQ------PPEGAA--EAVRAGDAAAPSLD-PATVAPPNTPVEPEPAPVEPPKPK-P 111
|
90 100
....*....|....*....|...
gi 2024460663 98 AKKKPPALKHSNTARKQLKAKPT 120
Cdd:PRK11633 112 VEKPKPKPKPQQKVEAPPAPKPE 134
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
25-203 |
6.06e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 40.54 E-value: 6.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 25 GRPEAAPLPASPRPLPADEASMGGPRQGAALNLLPAAEDSPKPAVEGPSLRAQS---HISPAPTTDPgadtkqtfPAKKK 101
Cdd:PHA03307 773 ALLEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPdggSESSGPARPP--------GAAAR 844
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 102 PPALKHSNTARKQLKAKPTLPGLSRAVSTQGSVLPvssqePSIPMETADGQRQSPPELPGwGPTSRPllqiSPFTPVPST 181
Cdd:PHA03307 845 PPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEP-----RARPGAAAPPKAAAAAPPAG-APAPRP----RPAPRVKLG 914
|
170 180 190
....*....|....*....|....*....|
gi 2024460663 182 AQPfPGGPGD--------VGTGPTAAPSGA 203
Cdd:PHA03307 915 PMP-PGGPDPrggfrrvpPGDLHTPAPSAA 943
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
17-223 |
8.53e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 39.91 E-value: 8.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 17 SPAAPRPDGRPEAAPLPASPRPLPAdeasmggprqgaalnllpaaedSPKPaVEGPSLRAQSHISPAPTTDPGADTKQTF 96
Cdd:PLN03209 372 SPYTAYEDLKPPTSPIPTPPSSSPA----------------------SSKS-VDAVAKPAEPDVVPSPGSASNVPEVEPA 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024460663 97 PAKKKPPALKHSNTARKQLKAkPTLPGLS--RAVSTQGSVLPVSSQEPSIPMETADGQRQSPPElpgwgPTSRPLlqiSP 174
Cdd:PLN03209 429 QVEAKKTRPLSPYARYEDLKP-PTSPSPTapTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPP-----ANMRPL---SP 499
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2024460663 175 FtPVPSTAQPfPGGPGDVGTGPTAAPSGAINQMDSAESEMNGSASEESQ 223
Cdd:PLN03209 500 Y-AVYDDLKP-PTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQH 546
|
|
| |
