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Conserved domains on  [gi|2024393276|ref|XP_040553680|]
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protocadherin Fat 4 isoform X1 [Gallus gallus]

Protein Classification

cadherin repeat domain-containing protein( domain architecture ID 10182847)

cadherin repeat domain-containing protein similar to cadherins, which are calcium-dependent cell adhesion proteins that preferentially interact with themselves in connecting cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 808-907 2.81e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 2.81e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  808 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 887
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNE---DGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                           90       100
                   ....*....|....*....|
gi 2024393276  888 QPSLNTSTHVVIHVLDVNDN 907
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 707-799 3.01e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 3.01e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  707 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRL 783
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPsTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                           90
                   ....*....|....*.
gi 2024393276  784 SAVLNLTVVIDDVNDN 799
Cdd:cd11304     83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1435-1526 1.45e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.00  E-value: 1.45e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1435 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1510
Cdd:cd11304      2 YEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEdglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*.
gi 2024393276 1511 LQDTTNITVIVEDVNE 1526
Cdd:cd11304     82 LSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1017-1116 1.78e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.00  E-value: 1.78e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1017 SYSFAVLEGdyrLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDN 1095
Cdd:cd11304      1 SYEVSVPEN---APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|.
gi 2024393276 1096 GMPRRQNFTYISIQVLDVNDN 1116
Cdd:cd11304     78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1848-1942 6.19e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.46  E-value: 6.19e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1848 FSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGG-NIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFy 1926
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL- 82

                           90
                   ....*....|....*.
gi 2024393276 1927 QATTNVTVLVIDVNDN 1942
Cdd:cd11304     83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1334-1426 6.82e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 6.82e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1334 LSLPENMAPLD-LGTFSATDLDIGDNAFISYYLQY-DFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1411
Cdd:cd11304      4 VSVPENAPPGTvVLTVSATDPDSGENGEVTYSIVSgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....*
gi 2024393276 1412 ASLALSIAVEDVNDN 1426
Cdd:cd11304     84 STATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1746-1837 3.57e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 3.57e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1746 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGDGT-KFRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPeKKR 1823
Cdd:cd11304      6 VPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGGGP-PLS 83

                           90
                   ....*....|....
gi 2024393276 1824 GYCTVVVKITDVND 1837
Cdd:cd11304     84 STATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 503-594 5.71e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 5.71e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  503 QYEQVIFINMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGG 582
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGG 78

                           90
                   ....*....|..
gi 2024393276  583 TNPRSSSVPVHI 594
Cdd:cd11304     79 GPPLSSTATVTI 90
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 400-495 8.43e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.52  E-value: 8.43e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  400 SYNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLTP--ADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHL 475
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEvTYSIVSgnEDGLFSIDPStGEITTAKP--LDREEQSSYTLTVTATDGG 78

                           90       100
                   ....*....|....*....|
gi 2024393276  476 SPYDEAQSAINVLLLDENDN 495
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1231-1322 1.29e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.29e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1231 YEFNIPEEEPVRTVVGSVKA--LTGSIAIQVVYFLRSHTD--KFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPP 1305
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSAtdPDSGENGEVTYSIVSGNEdgLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 2024393276 1306 NTAIALVTVIVNDINDN 1322
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1960-2043 3.43e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.89  E-value: 3.43e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1960 PVGVHVITVHATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAV 2036
Cdd:cd11304     11 PPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI--DPSTGEITTAKPLDR-EEQSsytLTVTATDGGGPPLSSTAT 87


                   ....*..
gi 2024393276 2037 ITLNVID 2043
Cdd:cd11304     88 VTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1535-1631 1.17e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.17e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1535 SYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGL 1614
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGGG 79

                           90
                   ....*....|....*..
gi 2024393276 1615 PPLSTSVKVSVTIAPTN 1631
Cdd:cd11304     80 PPLSSTATVTITVLDVN 96
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 187-278 1.52e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.52e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  187 YNTSVSEVSAINSTVIKVEAQDKDlSPLFSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 265
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....
gi 2024393276  266 -NSNTVSLIIDVQD 278
Cdd:cd11304     81 pLSSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1124-1219 3.09e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.20  E-value: 3.09e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1124 HYAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHG 1201
Cdd:cd11304      1 SYEVSVP-ENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGG 78

                           90
                   ....*....|....*....
gi 2024393276 1202 VPPLASNASVAVCLL-VND 1219
Cdd:cd11304     79 GPPLSSTATVTITVLdVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 290-392 5.30e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.73  E-value: 5.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  290 VYNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAA 369
Cdd:cd11304      1 SYEVSVPENAPPGTVVL--TVSATDPDSGENGEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTAT 75

                           90       100
                   ....*....|....*....|...
gi 2024393276  370 QQDNNLKTADAVVLVTIEDVNDN 392
Cdd:cd11304     76 DGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2057-2157 4.18e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.03  E-value: 4.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2057 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2133
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATdpdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTA----TDGG 78

                           90       100
                   ....*....|....*....|....
gi 2024393276 2134 QVPSSGlfaqnVAMLTITVQDVNE 2157
Cdd:cd11304     79 GPPLSS-----TATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1645-1732 1.36e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 68.49  E-value: 1.36e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1645 APLSEKTLPDTFVVQITVL-----YKVPVVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIF 1718
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATdpdsgENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEqSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....
gi 2024393276 1719 NDVSVHVEVIDEND 1732
Cdd:cd11304     84 STATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2166-2253 2.57e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 2.57e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2166 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2241
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDReEQSSYtLTVTATDGGGPP 81

                           90
                   ....*....|..
gi 2024393276 2242 AHTTVNATIYVT 2253
Cdd:cd11304     82 LSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 648-699 1.24e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


:

Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 53.89  E-value: 1.24e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024393276   648 FDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT---TDYATVFIQVTDVNDNSP 699
Cdd:smart00112   26 FSIDpETGEITTTKPLDREEQPEYTLTVEATDGGGpplSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 934-1011 3.45e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


:

Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 52.74  E-value: 3.45e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   934 SVTDDDEAGFSQGHFI----HNSTFFTVD-IPGIISLRNdtELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVND 1008
Cdd:smart00112    1 SATDADSGENGKVTYSilsgNDDGLFSIDpETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 2024393276  1009 NNP 1011
Cdd:smart00112   79 NAP 81
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 808-907 2.81e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 2.81e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  808 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 887
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNE---DGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                           90       100
                   ....*....|....*....|
gi 2024393276  888 QPSLNTSTHVVIHVLDVNDN 907
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 707-799 3.01e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 3.01e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  707 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRL 783
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPsTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                           90
                   ....*....|....*.
gi 2024393276  784 SAVLNLTVVIDDVNDN 799
Cdd:cd11304     83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1435-1526 1.45e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.00  E-value: 1.45e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1435 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1510
Cdd:cd11304      2 YEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEdglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*.
gi 2024393276 1511 LQDTTNITVIVEDVNE 1526
Cdd:cd11304     82 LSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1017-1116 1.78e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.00  E-value: 1.78e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1017 SYSFAVLEGdyrLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDN 1095
Cdd:cd11304      1 SYEVSVPEN---APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|.
gi 2024393276 1096 GMPRRQNFTYISIQVLDVNDN 1116
Cdd:cd11304     78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1848-1942 6.19e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.46  E-value: 6.19e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1848 FSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGG-NIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFy 1926
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL- 82

                           90
                   ....*....|....*.
gi 2024393276 1927 QATTNVTVLVIDVNDN 1942
Cdd:cd11304     83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1334-1426 6.82e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 6.82e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1334 LSLPENMAPLD-LGTFSATDLDIGDNAFISYYLQY-DFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1411
Cdd:cd11304      4 VSVPENAPPGTvVLTVSATDPDSGENGEVTYSIVSgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....*
gi 2024393276 1412 ASLALSIAVEDVNDN 1426
Cdd:cd11304     84 STATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 826-909 2.76e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 90.10  E-value: 2.76e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   826 SATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQPSLNTSTHVVIHVLDVN 905
Cdd:smart00112    1 SATDADSGENGKVTYSILSGND---DGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 2024393276   906 DNPP 909
Cdd:smart00112   78 DNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1746-1837 3.57e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 3.57e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1746 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGDGT-KFRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPeKKR 1823
Cdd:cd11304      6 VPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGGGP-PLS 83

                           90
                   ....*....|....
gi 2024393276 1824 GYCTVVVKITDVND 1837
Cdd:cd11304     84 STATVTITVLDVND 97
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1039-1118 4.02e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.63  E-value: 4.02e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1039 TATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDNGMPRRQNFTYISIQVLDVNDNV 1117
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024393276  1118 P 1118
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1349-1428 9.37e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 85.48  E-value: 9.37e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1349 SATDLDIGDNAFISYYLQYDFA-GMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLSASLALSIAVEDVNDNS 1427
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024393276  1428 P 1428
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 503-594 5.71e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 5.71e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  503 QYEQVIFINMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGG 582
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGG 78

                           90
                   ....*....|..
gi 2024393276  583 TNPRSSSVPVHI 594
Cdd:cd11304     79 GPPLSSTATVTI 90
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 725-801 7.45e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 83.17  E-value: 7.45e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   725 ATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPP 801
Cdd:smart00112    2 ATDADSGENGKVTYSILSgnDDGLFSIDPeTGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 400-495 8.43e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.52  E-value: 8.43e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  400 SYNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLTP--ADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHL 475
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEvTYSIVSgnEDGLFSIDPStGEITTAKP--LDREEQSSYTLTVTATDGG 78

                           90       100
                   ....*....|....*....|
gi 2024393276  476 SPYDEAQSAINVLLLDENDN 495
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1231-1322 1.29e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.29e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1231 YEFNIPEEEPVRTVVGSVKA--LTGSIAIQVVYFLRSHTD--KFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPP 1305
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSAtdPDSGENGEVTYSIVSGNEdgLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 2024393276 1306 NTAIALVTVIVNDINDN 1322
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
808-902 6.37e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.81  E-value: 6.37e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  808 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 887
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGP---GGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 2024393276  888 QPSLNTSTHVVIHVL 902
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1435-1522 1.02e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.04  E-value: 1.02e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1435 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1510
Cdd:pfam00028    1 YSASVPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGPggnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024393276 1511 LQDTTNITVIVE 1522
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1760-1840 2.14e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.93  E-value: 2.14e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1760 ARDNDTGRNGDLTYGILSG-DGTKFRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPEkKRGYCTVVVKITDVNDW 1838
Cdd:smart00112    2 ATDADSGENGKVTYSILSGnDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGPP-LSSTATVTITVLDVNDN 79


                    ..
gi 2024393276  1839 PP 1840
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1452-1529 2.56e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.55  E-value: 2.56e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1452 TATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDVNEEG 1528
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdglFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024393276  1529 P 1529
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1960-2043 3.43e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.89  E-value: 3.43e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1960 PVGVHVITVHATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAV 2036
Cdd:cd11304     11 PPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI--DPSTGEITTAKPLDR-EEQSsytLTVTATDGGGPPLSSTAT 87


                   ....*..
gi 2024393276 2037 ITLNVID 2043
Cdd:cd11304     88 VTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1535-1631 1.17e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.17e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1535 SYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGL 1614
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGGG 79

                           90
                   ....*....|....*..
gi 2024393276 1615 PPLSTSVKVSVTIAPTN 1631
Cdd:cd11304     80 PPLSSTATVTITVLDVN 96
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 187-278 1.52e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.52e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  187 YNTSVSEVSAINSTVIKVEAQDKDlSPLFSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 265
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....
gi 2024393276  266 -NSNTVSLIIDVQD 278
Cdd:cd11304     81 pLSSTATVTITVLD 94
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1864-1944 1.81e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 76.23  E-value: 1.81e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1864 TAMDRDTGDNAFVLYSLTGGG-GNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNkSAPFYQATTNVTVLVIDVNDN 1942
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNdDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024393276  1943 AP 1944
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1124-1219 3.09e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.20  E-value: 3.09e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1124 HYAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHG 1201
Cdd:cd11304      1 SYEVSVP-ENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGG 78

                           90
                   ....*....|....*....
gi 2024393276 1202 VPPLASNASVAVCLL-VND 1219
Cdd:cd11304     79 GPPLSSTATVTITVLdVND 97
Cadherin pfam00028
Cadherin domain;
707-793 6.37e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.03  E-value: 6.37e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  707 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLK--GAEGKMDID-ASGLILLKKELDRETQGIYNLAVIASDQGQPRL 783
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|
gi 2024393276  784 SAVLNLTVVI 793
Cdd:pfam00028   82 SSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1335-1421 1.97e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 73.87  E-value: 1.97e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1335 SLPENmAPLD--LGTFSATDLDIGDNAFISYYLQYDF-AGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1411
Cdd:pfam00028    4 SVPEN-APVGteVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82

                           90
                   ....*....|
gi 2024393276 1412 ASLALSIAVE 1421
Cdd:pfam00028   83 STATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 290-392 5.30e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.73  E-value: 5.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  290 VYNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAA 369
Cdd:cd11304      1 SYEVSVPENAPPGTVVL--TVSATDPDSGENGEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTAT 75

                           90       100
                   ....*....|....*....|...
gi 2024393276  370 QQDNNLKTADAVVLVTIEDVNDN 392
Cdd:cd11304     76 DGGGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1018-1111 3.10e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.41  E-value: 3.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1018 YSFAVLEGDyRLGAPavVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDNG 1096
Cdd:pfam00028    1 YSASVPENA-PVGTE--VLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 2024393276 1097 MPRRQNFTYISIQVL 1111
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2057-2157 4.18e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.03  E-value: 4.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2057 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2133
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATdpdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTA----TDGG 78

                           90       100
                   ....*....|....*....|....
gi 2024393276 2134 QVPSSGlfaqnVAMLTITVQDVNE 2157
Cdd:cd11304     79 GPPLSS-----TATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
1847-1937 5.10e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 5.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1847 PFSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGG-GNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPF 1925
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|..
gi 2024393276 1926 YQaTTNVTVLVI 1937
Cdd:pfam00028   82 SS-TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1645-1732 1.36e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 68.49  E-value: 1.36e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1645 APLSEKTLPDTFVVQITVL-----YKVPVVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIF 1718
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATdpdsgENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEqSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....
gi 2024393276 1719 NDVSVHVEVIDEND 1732
Cdd:cd11304     84 STATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
511-594 1.69e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.10  E-value: 1.69e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  511 NMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGGTNPRSSSV 590
Cdd:pfam00028    8 NAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTK--PLDRESIGEYELTVEATDSGGPPLSSTA 85


                   ....
gi 2024393276  591 PVHI 594
Cdd:pfam00028   86 TVTI 89
Cadherin pfam00028
Cadherin domain;
1746-1833 2.45e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 67.71  E-value: 2.45e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1746 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGD-GTKFRIDESTGILYSTVSFDYeEEPTEYQVVIYAEDDGTPeKKR 1823
Cdd:pfam00028    5 VPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDR-ESIGEYELTVEATDSGGP-PLS 82

                           90
                   ....*....|
gi 2024393276 1824 GYCTVVVKIT 1833
Cdd:pfam00028   83 STATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1258-1324 3.14e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 3.14e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1258 QVVYFL--RSHTDKFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPP 1324
Cdd:smart00112   12 KVTYSIlsGNDDGLFSIdPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 523-594 8.24e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.83  E-value: 8.24e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024393276   523 ADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGGTNPRSSSVPVHI 594
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTI 71
Cadherin pfam00028
Cadherin domain;
1543-1627 1.54e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 1.54e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1543 NSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGLPPLSTSVK 1622
Cdd:pfam00028    8 NAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYE-LTVEATDSGGPPLSSTAT 86


                   ....*
gi 2024393276 1623 VSVTI 1627
Cdd:pfam00028   87 VTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2166-2253 2.57e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 2.57e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2166 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2241
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDReEQSSYtLTVTATDGGGPP 81

                           90
                   ....*....|..
gi 2024393276 2242 AHTTVNATIYVT 2253
Cdd:cd11304     82 LSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1668-1735 3.66e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 63.91  E-value: 3.66e-12
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024393276  1668 VVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPP 1735
Cdd:smart00112   13 VTYSILSGNDDGLFSIDPETGEITTTKPLDREEqPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
1960-2042 3.97e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.24  E-value: 3.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1960 PVGVHVITVHATDKDQGQNGLIEYYIIPDlNFSAFFLIEDESeGKIITTGNLSRFE--EVCLTVMAKDKGSPSLNSTAVI 2037
Cdd:pfam00028   10 PVGTEVLTVTATDPDLGPNGRIFYSILGG-GPGGNFRIDPDT-GDISTTKPLDRESigEYELTVEATDSGGPPLSSTATV 87


                   ....*
gi 2024393276 2038 TLNVI 2042
Cdd:pfam00028   88 TITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 312-394 9.17e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 62.75  E-value: 9.17e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   312 AKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVND 391
Cdd:smart00112    2 ATDADSGENGKVTYSIL---SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 2024393276   392 NLP 394
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2083-2159 2.27e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 2.27e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024393276  2083 IVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAAQVPSSGlfaqnVAMLTITVQDVNEKP 2159
Cdd:smart00112   13 VTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEA----TDGGGPPLSS-----TATVTITVLDVNDNA 80
Cadherin pfam00028
Cadherin domain;
2057-2153 2.63e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.93  E-value: 2.63e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2057 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2133
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATdpdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA----TDSG 77

                           90       100
                   ....*....|....*....|
gi 2024393276 2134 QVPSSGlfaqnVAMLTITVQ 2153
Cdd:pfam00028   78 GPPLSS-----TATVTITVL 92
Cadherin pfam00028
Cadherin domain;
187-277 4.45e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.16  E-value: 4.45e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  187 YNTSVSEVSAINSTVIKVEAQDKDLSPLfSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 265
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPN-GRIFYSILGGGPGgNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024393276  266 N-SNTVSLIIDVQ 277
Cdd:pfam00028   80 PlSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1144-1219 5.80e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.44  E-value: 5.80e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024393276  1144 SATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHGVPPLASNASVAVCLL-VND 1219
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGPPLSSTATVTITVLdVND 78
Cadherin pfam00028
Cadherin domain;
1231-1316 6.38e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.78  E-value: 6.38e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1231 YEFNIPEEEPVRTVVGSVKAL---TGSIAiQVVYFLRSHT--DKFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVP 1304
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdpdLGPNG-RIFYSILGGGpgGNFRIdPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 2024393276 1305 PNTAIALVTVIV 1316
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1125-1213 7.83e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.78  E-value: 7.83e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1125 YAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLMNH--SDIFHINNHTGEIILLSSLAHVTADMvVTLTVIAADHGV 1202
Cdd:pfam00028    1 YSASVP-ENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgpGGNFRIDPDTGDISTTKPLDRESIGE-YELTVEATDSGG 78

                           90
                   ....*....|.
gi 2024393276 1203 PPLASNASVAV 1213
Cdd:pfam00028   79 PPLSSTATVTI 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1969-2046 1.05e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.06  E-value: 1.05e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1969 HATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAVITLNVID-- 2043
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSI--DPETGEITTTKPLDR-EEQPeytLTVEATDGGGPPLSSTATVTITVLDvn 77


                    ....
gi 2024393276  2044 -NRP 2046
Cdd:smart00112   78 dNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 420-497 1.12e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.67  E-value: 1.12e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   420 AVDKDEGGFQG-TFSLTP--ADSPFQI-SQDGILTVRNStlLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDN 495
Cdd:smart00112    2 ATDADSGENGKvTYSILSgnDDGLFSIdPETGEITTTKP--LDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024393276   496 NP 497
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1555-1627 1.44e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.67  E-value: 1.44e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024393276  1555 ARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGLPPLSTSVKVSVTI 1627
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSSTATVTITV 73
Cadherin pfam00028
Cadherin domain;
2166-2253 1.19e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 57.31  E-value: 1.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2166 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLLNHQE--QFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2241
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPggNFRIDPDTGDISTTKPLDReSIGEYeLTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024393276 2242 AHTTVNATIYVT 2253
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
401-490 3.41e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 55.77  E-value: 3.41e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  401 YNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLT--PADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHLS 476
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRiFYSILggGPGGNFRIDPDtGDISTTKP--LDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|....
gi 2024393276  477 PYDEAQSAINVLLL 490
Cdd:pfam00028   79 PPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 648-699 1.24e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 53.89  E-value: 1.24e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024393276   648 FDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT---TDYATVFIQVTDVNDNSP 699
Cdd:smart00112   26 FSIDpETGEITTTKPLDREEQPEYTLTVEATDGGGpplSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 934-1011 3.45e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 52.74  E-value: 3.45e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   934 SVTDDDEAGFSQGHFI----HNSTFFTVD-IPGIISLRNdtELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVND 1008
Cdd:smart00112    1 SATDADSGENGKVTYSilsgNDDGLFSIDpETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 2024393276  1009 NNP 1011
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 206-278 7.46e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 51.97  E-value: 7.46e-08
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024393276   206 AQDKDlSPLFSHISYSLLGPN-SDYFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGNN-SNTVSLIIDVQD 278
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNdDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPlSSTATVTITVLD 75
Cadherin pfam00028
Cadherin domain;
1643-1728 1.06e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 51.53  E-value: 1.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1643 QPAPLSEKTLPDTFVVQITVL-YKVP----VVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTAS 1716
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdPDLGpngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESiGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024393276 1717 IFNDVSVHVEVI 1728
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2184-2253 6.67e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 49.27  E-value: 6.67e-07
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024393276  2184 QATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLTAHTTVNATIYVT 2253
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDReEQPEYtLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
291-387 4.80e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 46.91  E-value: 4.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  291 YNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAaq 370
Cdd:pfam00028    1 YSASVPENAPVGTEVL--TVTATDPDLGPNGRIFYSIL---GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA-- 73

                           90
                   ....*....|....*..
gi 2024393276  371 QDNNLKTADAVVLVTIE 387
Cdd:pfam00028   74 TDSGGPPLSSTATVTIT 90
Cadherin pfam00028
Cadherin domain;
916-1004 1.83e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.67  E-value: 1.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  916 YDIVVFENIQKGSPVCTFSVTDDDEAG-------FSQGHFIHNstfFTVD-IPGIISLRndTELDRETTPGFTLQVWAVD 987
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngrifysILGGGPGGN---FRIDpDTGDISTT--KPLDRESIGEYELTVEATD 75

                           90
                   ....*....|....*..
gi 2024393276  988 AEKDGLNSSSLFHITVL 1004
Cdd:pfam00028   76 SGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
609-692 1.85e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.67  E-value: 1.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  609 YNVSVEEELVSPVEVARVKY--ESLNPHIPVILRVLT--ESATFDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT-- 681
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTAtdPDLGPNGRIFYSILGggPGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGpp 80

                           90
                   ....*....|..
gi 2024393276  682 -TDYATVFIQVT 692
Cdd:pfam00028   81 lSSTATVTITVL 92
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 808-907 2.81e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.56  E-value: 2.81e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  808 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 887
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNE---DGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                           90       100
                   ....*....|....*....|
gi 2024393276  888 QPSLNTSTHVVIHVLDVNDN 907
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 707-799 3.01e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 3.01e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  707 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRL 783
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPsTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                           90
                   ....*....|....*.
gi 2024393276  784 SAVLNLTVVIDDVNDN 799
Cdd:cd11304     83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1435-1526 1.45e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.00  E-value: 1.45e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1435 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1510
Cdd:cd11304      2 YEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEdglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*.
gi 2024393276 1511 LQDTTNITVIVEDVNE 1526
Cdd:cd11304     82 LSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1017-1116 1.78e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 97.00  E-value: 1.78e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1017 SYSFAVLEGdyrLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDN 1095
Cdd:cd11304      1 SYEVSVPEN---APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDG 77

                           90       100
                   ....*....|....*....|.
gi 2024393276 1096 GMPRRQNFTYISIQVLDVNDN 1116
Cdd:cd11304     78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1848-1942 6.19e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.46  E-value: 6.19e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1848 FSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGG-NIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFy 1926
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL- 82

                           90
                   ....*....|....*.
gi 2024393276 1927 QATTNVTVLVIDVNDN 1942
Cdd:cd11304     83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1334-1426 6.82e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 6.82e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1334 LSLPENMAPLD-LGTFSATDLDIGDNAFISYYLQY-DFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1411
Cdd:cd11304      4 VSVPENAPPGTvVLTVSATDPDSGENGEVTYSIVSgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....*
gi 2024393276 1412 ASLALSIAVEDVNDN 1426
Cdd:cd11304     84 STATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 826-909 2.76e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 90.10  E-value: 2.76e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   826 SATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQPSLNTSTHVVIHVLDVN 905
Cdd:smart00112    1 SATDADSGENGKVTYSILSGND---DGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 2024393276   906 DNPP 909
Cdd:smart00112   78 DNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1746-1837 3.57e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 87.37  E-value: 3.57e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1746 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGDGT-KFRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPeKKR 1823
Cdd:cd11304      6 VPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGGGP-PLS 83

                           90
                   ....*....|....
gi 2024393276 1824 GYCTVVVKITDVND 1837
Cdd:cd11304     84 STATVTITVLDVND 97
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1039-1118 4.02e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.63  E-value: 4.02e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1039 TATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDNGMPRRQNFTYISIQVLDVNDNV 1117
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024393276  1118 P 1118
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1349-1428 9.37e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 85.48  E-value: 9.37e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1349 SATDLDIGDNAFISYYLQYDFA-GMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLSASLALSIAVEDVNDNS 1427
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024393276  1428 P 1428
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 503-594 5.71e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.90  E-value: 5.71e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  503 QYEQVIFINMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGG 582
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGG 78

                           90
                   ....*....|..
gi 2024393276  583 TNPRSSSVPVHI 594
Cdd:cd11304     79 GPPLSSTATVTI 90
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 725-801 7.45e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 83.17  E-value: 7.45e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   725 ATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPP 801
Cdd:smart00112    2 ATDADSGENGKVTYSILSgnDDGLFSIDPeTGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 400-495 8.43e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.52  E-value: 8.43e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  400 SYNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLTP--ADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHL 475
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEvTYSIVSgnEDGLFSIDPStGEITTAKP--LDREEQSSYTLTVTATDGG 78

                           90       100
                   ....*....|....*....|
gi 2024393276  476 SPYDEAQSAINVLLLDENDN 495
Cdd:cd11304     79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1231-1322 1.29e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.29e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1231 YEFNIPEEEPVRTVVGSVKA--LTGSIAIQVVYFLRSHTD--KFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPP 1305
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSAtdPDSGENGEVTYSIVSGNEdgLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                           90
                   ....*....|....*..
gi 2024393276 1306 NTAIALVTVIVNDINDN 1322
Cdd:cd11304     82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
808-902 6.37e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.81  E-value: 6.37e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  808 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 887
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGP---GGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 2024393276  888 QPSLNTSTHVVIHVL 902
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1435-1522 1.02e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.04  E-value: 1.02e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1435 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1510
Cdd:pfam00028    1 YSASVPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGPggnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024393276 1511 LQDTTNITVIVE 1522
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1760-1840 2.14e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.93  E-value: 2.14e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1760 ARDNDTGRNGDLTYGILSG-DGTKFRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPEkKRGYCTVVVKITDVNDW 1838
Cdd:smart00112    2 ATDADSGENGKVTYSILSGnDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGPP-LSSTATVTITVLDVNDN 79


                    ..
gi 2024393276  1839 PP 1840
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1452-1529 2.56e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.55  E-value: 2.56e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1452 TATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDVNEEG 1528
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdglFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 2024393276  1529 P 1529
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1960-2043 3.43e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.89  E-value: 3.43e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1960 PVGVHVITVHATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAV 2036
Cdd:cd11304     11 PPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI--DPSTGEITTAKPLDR-EEQSsytLTVTATDGGGPPLSSTAT 87


                   ....*..
gi 2024393276 2037 ITLNVID 2043
Cdd:cd11304     88 VTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1535-1631 1.17e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.17e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1535 SYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGL 1614
Cdd:cd11304      1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGGG 79

                           90
                   ....*....|....*..
gi 2024393276 1615 PPLSTSVKVSVTIAPTN 1631
Cdd:cd11304     80 PPLSSTATVTITVLDVN 96
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 187-278 1.52e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.52e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  187 YNTSVSEVSAINSTVIKVEAQDKDlSPLFSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 265
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                           90
                   ....*....|....
gi 2024393276  266 -NSNTVSLIIDVQD 278
Cdd:cd11304     81 pLSSTATVTITVLD 94
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1864-1944 1.81e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 76.23  E-value: 1.81e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1864 TAMDRDTGDNAFVLYSLTGGG-GNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNkSAPFYQATTNVTVLVIDVNDN 1942
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNdDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024393276  1943 AP 1944
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1124-1219 3.09e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.20  E-value: 3.09e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1124 HYAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHG 1201
Cdd:cd11304      1 SYEVSVP-ENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGG 78

                           90
                   ....*....|....*....
gi 2024393276 1202 VPPLASNASVAVCLL-VND 1219
Cdd:cd11304     79 GPPLSSTATVTITVLdVND 97
Cadherin pfam00028
Cadherin domain;
707-793 6.37e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.03  E-value: 6.37e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  707 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLK--GAEGKMDID-ASGLILLKKELDRETQGIYNLAVIASDQGQPRL 783
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|
gi 2024393276  784 SAVLNLTVVI 793
Cdd:pfam00028   82 SSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1335-1421 1.97e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 73.87  E-value: 1.97e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1335 SLPENmAPLD--LGTFSATDLDIGDNAFISYYLQYDF-AGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1411
Cdd:pfam00028    4 SVPEN-APVGteVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82

                           90
                   ....*....|
gi 2024393276 1412 ASLALSIAVE 1421
Cdd:pfam00028   83 STATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 290-392 5.30e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.73  E-value: 5.30e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  290 VYNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAA 369
Cdd:cd11304      1 SYEVSVPENAPPGTVVL--TVSATDPDSGENGEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTAT 75

                           90       100
                   ....*....|....*....|...
gi 2024393276  370 QQDNNLKTADAVVLVTIEDVNDN 392
Cdd:cd11304     76 DGGGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1018-1111 3.10e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.41  E-value: 3.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1018 YSFAVLEGDyRLGAPavVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDNG 1096
Cdd:pfam00028    1 YSASVPENA-PVGTE--VLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 2024393276 1097 MPRRQNFTYISIQVL 1111
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2057-2157 4.18e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.03  E-value: 4.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2057 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2133
Cdd:cd11304      3 EVSVPENAPPGTVVLTVSATdpdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTA----TDGG 78

                           90       100
                   ....*....|....*....|....
gi 2024393276 2134 QVPSSGlfaqnVAMLTITVQDVNE 2157
Cdd:cd11304     79 GPPLSS-----TATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
1847-1937 5.10e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 5.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1847 PFSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGG-GNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPF 1925
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|..
gi 2024393276 1926 YQaTTNVTVLVI 1937
Cdd:pfam00028   82 SS-TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1645-1732 1.36e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 68.49  E-value: 1.36e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1645 APLSEKTLPDTFVVQITVL-----YKVPVVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIF 1718
Cdd:cd11304      4 VSVPENAPPGTVVLTVSATdpdsgENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEqSSYTLTVTATDGGGPPLS 83

                           90
                   ....*....|....
gi 2024393276 1719 NDVSVHVEVIDEND 1732
Cdd:cd11304     84 STATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
511-594 1.69e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.10  E-value: 1.69e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  511 NMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGGTNPRSSSV 590
Cdd:pfam00028    8 NAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTK--PLDRESIGEYELTVEATDSGGPPLSSTA 85


                   ....
gi 2024393276  591 PVHI 594
Cdd:pfam00028   86 TVTI 89
Cadherin pfam00028
Cadherin domain;
1746-1833 2.45e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 67.71  E-value: 2.45e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1746 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGD-GTKFRIDESTGILYSTVSFDYeEEPTEYQVVIYAEDDGTPeKKR 1823
Cdd:pfam00028    5 VPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDR-ESIGEYELTVEATDSGGP-PLS 82

                           90
                   ....*....|
gi 2024393276 1824 GYCTVVVKIT 1833
Cdd:pfam00028   83 STATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1258-1324 3.14e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 3.14e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1258 QVVYFL--RSHTDKFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPP 1324
Cdd:smart00112   12 KVTYSIlsGNDDGLFSIdPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 523-594 8.24e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.83  E-value: 8.24e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024393276   523 ADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGGTNPRSSSVPVHI 594
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTI 71
Cadherin pfam00028
Cadherin domain;
1543-1627 1.54e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 1.54e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1543 NSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGLPPLSTSVK 1622
Cdd:pfam00028    8 NAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYE-LTVEATDSGGPPLSSTAT 86


                   ....*
gi 2024393276 1623 VSVTI 1627
Cdd:pfam00028   87 VTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2166-2253 2.57e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 2.57e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2166 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2241
Cdd:cd11304      2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDReEQSSYtLTVTATDGGGPP 81

                           90
                   ....*....|..
gi 2024393276 2242 AHTTVNATIYVT 2253
Cdd:cd11304     82 LSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1668-1735 3.66e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 63.91  E-value: 3.66e-12
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024393276  1668 VVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPP 1735
Cdd:smart00112   13 VTYSILSGNDDGLFSIDPETGEITTTKPLDREEqPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
1960-2042 3.97e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.24  E-value: 3.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1960 PVGVHVITVHATDKDQGQNGLIEYYIIPDlNFSAFFLIEDESeGKIITTGNLSRFE--EVCLTVMAKDKGSPSLNSTAVI 2037
Cdd:pfam00028   10 PVGTEVLTVTATDPDLGPNGRIFYSILGG-GPGGNFRIDPDT-GDISTTKPLDRESigEYELTVEATDSGGPPLSSTATV 87


                   ....*
gi 2024393276 2038 TLNVI 2042
Cdd:pfam00028   88 TITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 312-394 9.17e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 62.75  E-value: 9.17e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   312 AKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVND 391
Cdd:smart00112    2 ATDADSGENGKVTYSIL---SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 2024393276   392 NLP 394
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2083-2159 2.27e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 2.27e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024393276  2083 IVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAAQVPSSGlfaqnVAMLTITVQDVNEKP 2159
Cdd:smart00112   13 VTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEA----TDGGGPPLSS-----TATVTITVLDVNDNA 80
Cadherin pfam00028
Cadherin domain;
2057-2153 2.63e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.93  E-value: 2.63e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2057 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2133
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATdpdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA----TDSG 77

                           90       100
                   ....*....|....*....|
gi 2024393276 2134 QVPSSGlfaqnVAMLTITVQ 2153
Cdd:pfam00028   78 GPPLSS-----TATVTITVL 92
Cadherin pfam00028
Cadherin domain;
187-277 4.45e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.16  E-value: 4.45e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  187 YNTSVSEVSAINSTVIKVEAQDKDLSPLfSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 265
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPN-GRIFYSILGGGPGgNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 2024393276  266 N-SNTVSLIIDVQ 277
Cdd:pfam00028   80 PlSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1144-1219 5.80e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.44  E-value: 5.80e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024393276  1144 SATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHGVPPLASNASVAVCLL-VND 1219
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGPPLSSTATVTITVLdVND 78
Cadherin pfam00028
Cadherin domain;
1231-1316 6.38e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.78  E-value: 6.38e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1231 YEFNIPEEEPVRTVVGSVKAL---TGSIAiQVVYFLRSHT--DKFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVP 1304
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdpdLGPNG-RIFYSILGGGpgGNFRIdPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 2024393276 1305 PNTAIALVTVIV 1316
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1125-1213 7.83e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.78  E-value: 7.83e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1125 YAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLMNH--SDIFHINNHTGEIILLSSLAHVTADMvVTLTVIAADHGV 1202
Cdd:pfam00028    1 YSASVP-ENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgpGGNFRIDPDTGDISTTKPLDRESIGE-YELTVEATDSGG 78

                           90
                   ....*....|.
gi 2024393276 1203 PPLASNASVAV 1213
Cdd:pfam00028   79 PPLSSTATVTI 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1969-2046 1.05e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.06  E-value: 1.05e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  1969 HATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAVITLNVID-- 2043
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSI--DPETGEITTTKPLDR-EEQPeytLTVEATDGGGPPLSSTATVTITVLDvn 77


                    ....
gi 2024393276  2044 -NRP 2046
Cdd:smart00112   78 dNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 420-497 1.12e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.67  E-value: 1.12e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   420 AVDKDEGGFQG-TFSLTP--ADSPFQI-SQDGILTVRNStlLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDN 495
Cdd:smart00112    2 ATDADSGENGKvTYSILSgnDDGLFSIdPETGEITTTKP--LDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 2024393276   496 NP 497
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1555-1627 1.44e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.67  E-value: 1.44e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024393276  1555 ARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGLPPLSTSVKVSVTI 1627
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSSTATVTITV 73
Cadherin pfam00028
Cadherin domain;
2166-2253 1.19e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 57.31  E-value: 1.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 2166 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLLNHQE--QFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2241
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPggNFRIDPDTGDISTTKPLDReSIGEYeLTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024393276 2242 AHTTVNATIYVT 2253
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
401-490 3.41e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 55.77  E-value: 3.41e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  401 YNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLT--PADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHLS 476
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRiFYSILggGPGGNFRIDPDtGDISTTKP--LDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|....
gi 2024393276  477 PYDEAQSAINVLLL 490
Cdd:pfam00028   79 PPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 648-699 1.24e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 53.89  E-value: 1.24e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024393276   648 FDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT---TDYATVFIQVTDVNDNSP 699
Cdd:smart00112   26 FSIDpETGEITTTKPLDREEQPEYTLTVEATDGGGpplSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 934-1011 3.45e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 52.74  E-value: 3.45e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276   934 SVTDDDEAGFSQGHFI----HNSTFFTVD-IPGIISLRNdtELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVND 1008
Cdd:smart00112    1 SATDADSGENGKVTYSilsgNDDGLFSIDpETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 2024393276  1009 NNP 1011
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 206-278 7.46e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 51.97  E-value: 7.46e-08
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024393276   206 AQDKDlSPLFSHISYSLLGPN-SDYFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGNN-SNTVSLIIDVQD 278
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNdDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPlSSTATVTITVLD 75
Cadherin pfam00028
Cadherin domain;
1643-1728 1.06e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 51.53  E-value: 1.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276 1643 QPAPLSEKTLPDTFVVQITVL-YKVP----VVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTAS 1716
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdPDLGpngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESiGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 2024393276 1717 IFNDVSVHVEVI 1728
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2184-2253 6.67e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 49.27  E-value: 6.67e-07
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024393276  2184 QATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLTAHTTVNATIYVT 2253
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDReEQPEYtLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
291-387 4.80e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 46.91  E-value: 4.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  291 YNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAaq 370
Cdd:pfam00028    1 YSASVPENAPVGTEVL--TVTATDPDLGPNGRIFYSIL---GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA-- 73

                           90
                   ....*....|....*..
gi 2024393276  371 QDNNLKTADAVVLVTIE 387
Cdd:pfam00028   74 TDSGGPPLSSTATVTIT 90
Cadherin pfam00028
Cadherin domain;
916-1004 1.83e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.67  E-value: 1.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  916 YDIVVFENIQKGSPVCTFSVTDDDEAG-------FSQGHFIHNstfFTVD-IPGIISLRndTELDRETTPGFTLQVWAVD 987
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngrifysILGGGPGGN---FRIDpDTGDISTT--KPLDRESIGEYELTVEATD 75

                           90
                   ....*....|....*..
gi 2024393276  988 AEKDGLNSSSLFHITVL 1004
Cdd:pfam00028   76 SGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
609-692 1.85e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.67  E-value: 1.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024393276  609 YNVSVEEELVSPVEVARVKY--ESLNPHIPVILRVLT--ESATFDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT-- 681
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTAtdPDLGPNGRIFYSILGggPGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGpp 80

                           90
                   ....*....|..
gi 2024393276  682 -TDYATVFIQVT 692
Cdd:pfam00028   81 lSSTATVTITVL 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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