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Conserved domains on  [gi|2024422731|ref|XP_040560203|]
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thrombospondin type-1 domain-containing protein 7B isoform X2 [Gallus gallus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 585-643 9.56e-16

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 72.70  E-value: 9.56e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024422731  585 CVLSEWSQWSPCSHSCssksAEGSQSRSRSILALPAEGGKACPPdraLQEHRACNDHPC 643
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCPE---LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 172-223 2.26e-14

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 68.85  E-value: 2.26e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024422731  172 CVVTDFSPWSPCSGGCTNSLRHRTRAVIAPPLYGGAPCPNLTESQTCAAAAC 223
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1232-1285 2.47e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 65.76  E-value: 2.47e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731 1232 CRLSAWSAWSQCSQTCGsGGQMVRGRTVLLKAAAEGRPCPAqLSQHRSCPVKPC 1285
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCPE-LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 320-373 2.28e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 57.29  E-value: 2.28e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731  320 CETSEWSAWSSCSQTCswgdlAPGFRSRHRSVRSVAMGSGKLCPELEEKEACST 373
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPCNL 49
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 721-777 1.65e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 54.98  E-value: 1.65e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024422731  721 CIVTPFSEWTRCPTACQPGnatavKQSRYRIIIQDAANGGQACPDTLyEERECEDTP 777
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG-----VQTRTRTVIVEPQNGGRPCPELL-ERRPCNLPP 51
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 648-716 2.42e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 51.68  E-value: 2.42e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024422731  648 WETSPWSSCSedvlvtalnatvswsgeATCGVGMQTRKVFCMRSGSGHVTP-KRCPDSTRPETVRPCLLP 716
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1355-1414 2.51e-08

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19028:

Pssm-ID: 480609  Cd Length: 52  Bit Score: 51.51  E-value: 2.51e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024422731 1355 CHLTEWSEWSSCELTCidgrsfeTTGRQARSRALIGQPAENMESCsGQVVETRPCSGGRC 1414
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPC-PELLERRPCNLPPC 52
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1113-1164 5.76e-08

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19028:

Pssm-ID: 480609  Cd Length: 52  Bit Score: 50.74  E-value: 5.76e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731 1113 CAVSDWGPWSTCPQVCDPStVQTRTRQVLRSVSR--KPCPEDSQMKPCILnQNC 1164
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG-VQTRTRTVIVEPQNggRPCPELLERRPCNL-PPC 52
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1046-1107 3.59e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 48.60  E-value: 3.59e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024422731 1046 WVVEPWSPCkinseqnSLHCGEGIQTRKVRCVSTtedHGGETVPNTLCNKAEIPNEIRKCSL 1107
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQK---GGGSIVPDSECSAQKKPPETQSCNL 52
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 468-525 9.18e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19028:

Pssm-ID: 480609  Cd Length: 52  Bit Score: 44.19  E-value: 9.18e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024422731  468 CAVSAWLAWGPClPEDCRdrqgrRGFRMRQRHVIVDPVGTLAGCPHLVESIPCEDPTC 525
Cdd:pfam19028    1 CVVSEWSEWSEC-SVTCG-----GGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-94 1.43e-05

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 43.98  E-value: 1.43e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024422731   44 WKTGHWGRCVGDCGsGGTRSRAVWCTHT-EGWTSHHANCDQQEKPESQRRCF 94
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQKgGGSIVPDSECSAQKKPPETQSCN 51
 
Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 585-643 9.56e-16

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 72.70  E-value: 9.56e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024422731  585 CVLSEWSQWSPCSHSCssksAEGSQSRSRSILALPAEGGKACPPdraLQEHRACNDHPC 643
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCPE---LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 172-223 2.26e-14

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 68.85  E-value: 2.26e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024422731  172 CVVTDFSPWSPCSGGCTNSLRHRTRAVIAPPLYGGAPCPNLTESQTCAAAAC 223
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1232-1285 2.47e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 65.76  E-value: 2.47e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731 1232 CRLSAWSAWSQCSQTCGsGGQMVRGRTVLLKAAAEGRPCPAqLSQHRSCPVKPC 1285
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCPE-LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 320-373 2.28e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 57.29  E-value: 2.28e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731  320 CETSEWSAWSSCSQTCswgdlAPGFRSRHRSVRSVAMGSGKLCPELEEKEACST 373
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPCNL 49
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 721-777 1.65e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 54.98  E-value: 1.65e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024422731  721 CIVTPFSEWTRCPTACQPGnatavKQSRYRIIIQDAANGGQACPDTLyEERECEDTP 777
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG-----VQTRTRTVIVEPQNGGRPCPELL-ERRPCNLPP 51
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 648-716 2.42e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 51.68  E-value: 2.42e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024422731  648 WETSPWSSCSedvlvtalnatvswsgeATCGVGMQTRKVFCMRSGSGHVTP-KRCPDSTRPETVRPCLLP 716
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1355-1414 2.51e-08

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 51.51  E-value: 2.51e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024422731 1355 CHLTEWSEWSSCELTCidgrsfeTTGRQARSRALIGQPAENMESCsGQVVETRPCSGGRC 1414
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPC-PELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1113-1164 5.76e-08

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 50.74  E-value: 5.76e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731 1113 CAVSDWGPWSTCPQVCDPStVQTRTRQVLRSVSR--KPCPEDSQMKPCILnQNC 1164
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG-VQTRTRTVIVEPQNggRPCPELLERRPCNL-PPC 52
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1046-1107 3.59e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 48.60  E-value: 3.59e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024422731 1046 WVVEPWSPCkinseqnSLHCGEGIQTRKVRCVSTtedHGGETVPNTLCNKAEIPNEIRKCSL 1107
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQK---GGGSIVPDSECSAQKKPPETQSCNL 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1235-1285 2.34e-06

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 46.04  E-value: 2.34e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|.
gi 2024422731  1235 SAWSAWSQCSQTCGSGGQMVRGRTVLLKAAAEGRPCPAQLSQHRSCPVKPC 1285
Cdd:smart00209    2 SEWSEWSPCSVTCGGGVQTRTRSCCSPPPQNGGGPCTGEDVETRACNEQPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 468-525 9.18e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 44.19  E-value: 9.18e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024422731  468 CAVSAWLAWGPClPEDCRdrqgrRGFRMRQRHVIVDPVGTLAGCPHLVESIPCEDPTC 525
Cdd:pfam19028    1 CVVSEWSEWSEC-SVTCG-----GGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-94 1.43e-05

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 43.98  E-value: 1.43e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024422731   44 WKTGHWGRCVGDCGsGGTRSRAVWCTHT-EGWTSHHANCDQQEKPESQRRCF 94
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQKgGGSIVPDSECSAQKKPPETQSCN 51
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 588-643 2.45e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 43.34  E-value: 2.45e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024422731   588 SEWSQWSPCSHSCSsksaEGSQSRSRS-ILALPAEGGKACPPDRalQEHRACNDHPC 643
Cdd:smart00209    2 SEWSEWSPCSVTCG----GGVQTRTRScCSPPPQNGGGPCTGED--VETRACNEQPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 174-224 7.43e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.80  E-value: 7.43e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 2024422731   174 VTDFSPWSPCSGGCTNSLRHRTRAVI-APPLYGGAPCP-NLTESQTCAAAACP 224
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCsPPPQNGGGPCTgEDVETRACNEQPCP 53
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1358-1414 2.64e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 40.26  E-value: 2.64e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024422731  1358 TEWSEWSSCELTCidgrsfeTTGRQARSRALIGQPAENM-ESCSGQVVETRPCSGGRC 1414
Cdd:smart00209    2 SEWSEWSPCSVTC-------GGGVQTRTRSCCSPPPQNGgGPCTGEDVETRACNEQPC 52
 
Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 585-643 9.56e-16

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 72.70  E-value: 9.56e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024422731  585 CVLSEWSQWSPCSHSCssksAEGSQSRSRSILALPAEGGKACPPdraLQEHRACNDHPC 643
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCPE---LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 172-223 2.26e-14

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 68.85  E-value: 2.26e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024422731  172 CVVTDFSPWSPCSGGCTNSLRHRTRAVIAPPLYGGAPCPNLTESQTCAAAAC 223
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1232-1285 2.47e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 65.76  E-value: 2.47e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731 1232 CRLSAWSAWSQCSQTCGsGGQMVRGRTVLLKAAAEGRPCPAqLSQHRSCPVKPC 1285
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCPE-LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 320-373 2.28e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 57.29  E-value: 2.28e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731  320 CETSEWSAWSSCSQTCswgdlAPGFRSRHRSVRSVAMGSGKLCPELEEKEACST 373
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPCNL 49
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 721-777 1.65e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 54.98  E-value: 1.65e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024422731  721 CIVTPFSEWTRCPTACQPGnatavKQSRYRIIIQDAANGGQACPDTLyEERECEDTP 777
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG-----VQTRTRTVIVEPQNGGRPCPELL-ERRPCNLPP 51
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 648-716 2.42e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 51.68  E-value: 2.42e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024422731  648 WETSPWSSCSedvlvtalnatvswsgeATCGVGMQTRKVFCMRSGSGHVTP-KRCPDSTRPETVRPCLLP 716
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1355-1414 2.51e-08

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 51.51  E-value: 2.51e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024422731 1355 CHLTEWSEWSSCELTCidgrsfeTTGRQARSRALIGQPAENMESCsGQVVETRPCSGGRC 1414
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPC-PELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1113-1164 5.76e-08

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 50.74  E-value: 5.76e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024422731 1113 CAVSDWGPWSTCPQVCDPStVQTRTRQVLRSVSR--KPCPEDSQMKPCILnQNC 1164
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG-VQTRTRTVIVEPQNggRPCPELLERRPCNL-PPC 52
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1046-1107 3.59e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 48.60  E-value: 3.59e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024422731 1046 WVVEPWSPCkinseqnSLHCGEGIQTRKVRCVSTtedHGGETVPNTLCNKAEIPNEIRKCSL 1107
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQK---GGGSIVPDSECSAQKKPPETQSCNL 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1235-1285 2.34e-06

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 46.04  E-value: 2.34e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|.
gi 2024422731  1235 SAWSAWSQCSQTCGSGGQMVRGRTVLLKAAAEGRPCPAQLSQHRSCPVKPC 1285
Cdd:smart00209    2 SEWSEWSPCSVTCGGGVQTRTRSCCSPPPQNGGGPCTGEDVETRACNEQPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 468-525 9.18e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 44.19  E-value: 9.18e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024422731  468 CAVSAWLAWGPClPEDCRdrqgrRGFRMRQRHVIVDPVGTLAGCPHLVESIPCEDPTC 525
Cdd:pfam19028    1 CVVSEWSEWSEC-SVTCG-----GGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-94 1.43e-05

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 43.98  E-value: 1.43e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024422731   44 WKTGHWGRCVGDCGsGGTRSRAVWCTHT-EGWTSHHANCDQQEKPESQRRCF 94
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQKgGGSIVPDSECSAQKKPPETQSCN 51
TSP_1 pfam00090
Thrombospondin type 1 domain;
1235-1285 2.30e-05

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 43.18  E-value: 2.30e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024422731 1235 SAWSAWSQCSQTCGSgGQMVRGRTVlLKAAAEGRPCPAQLSQHRSCPVKPC 1285
Cdd:pfam00090    1 SPWSPWSPCSVTCGK-GIQVRQRTC-KSPFPGGEPCTGDDIETQACKMDKC 49
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 588-643 2.45e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 43.34  E-value: 2.45e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024422731   588 SEWSQWSPCSHSCSsksaEGSQSRSRS-ILALPAEGGKACPPDRalQEHRACNDHPC 643
Cdd:smart00209    2 SEWSEWSPCSVTCG----GGVQTRTRScCSPPPQNGGGPCTGED--VETRACNEQPC 52
TSP_1 pfam00090
Thrombospondin type 1 domain;
588-643 4.40e-05

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 42.41  E-value: 4.40e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024422731  588 SEWSQWSPCSHSCSSksaeGSQSRSRSILAlPAEGGKACPPDraLQEHRACNDHPC 643
Cdd:pfam00090    1 SPWSPWSPCSVTCGK----GIQVRQRTCKS-PFPGGEPCTGD--DIETQACKMDKC 49
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 174-224 7.43e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.80  E-value: 7.43e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 2024422731   174 VTDFSPWSPCSGGCTNSLRHRTRAVI-APPLYGGAPCP-NLTESQTCAAAACP 224
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCsPPPQNGGGPCTgEDVETRACNEQPCP 53
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1358-1414 2.64e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 40.26  E-value: 2.64e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024422731  1358 TEWSEWSSCELTCidgrsfeTTGRQARSRALIGQPAENM-ESCSGQVVETRPCSGGRC 1414
Cdd:smart00209    2 SEWSEWSPCSVTC-------GGGVQTRTRSCCSPPPQNGgGPCTGEDVETRACNEQPC 52
TSP_1 pfam00090
Thrombospondin type 1 domain;
1358-1414 5.80e-03

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 36.24  E-value: 5.80e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024422731 1358 TEWSEWSSCELTCIDgrsfettGRQARSRALIGQPAENmESCSGQVVETRPCSGGRC 1414
Cdd:pfam00090    1 SPWSPWSPCSVTCGK-------GIQVRQRTCKSPFPGG-EPCTGDDIETQACKMDKC 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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