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Conserved domains on  [gi|513174004|ref|XP_419273|]
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protocadherin Fat 4 isoform X3 [Gallus gallus]

Protein Classification

cadherin repeat domain-containing protein( domain architecture ID 10182847)

cadherin repeat domain-containing protein similar to cadherins, which are calcium-dependent cell adhesion proteins that preferentially interact with themselves in connecting cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 763-862 3.66e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.18  E-value: 3.66e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  763 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 842
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNE---DGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 513174004  843 QPSLNTSTHVVIHVLDVNDN 862
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 662-754 4.04e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.54  E-value: 4.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  662 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRL 738
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPsTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 513174004  739 SAVLNLTVVIDDVNDN 754
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1390-1481 1.91e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.61  E-value: 1.91e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1390 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1465
Cdd:cd11304     2 YEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEdglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*.
gi 513174004 1466 LQDTTNITVIVEDVNE 1481
Cdd:cd11304    82 LSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 972-1071 2.23e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.61  E-value: 2.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  972 SYSFAVLEGdyrLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDN 1050
Cdd:cd11304     1 SYEVSVPEN---APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 513174004 1051 GMPRRQNFTYISIQVLDVNDN 1071
Cdd:cd11304    78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1803-1897 8.21e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 8.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1803 FSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGG-NIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFy 1881
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL- 82

                          90
                  ....*....|....*.
gi 513174004 1882 QATTNVTVLVIDVNDN 1897
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1289-1381 8.79e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 8.79e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1289 LSLPENMAPLD-LGTFSATDLDIGDNAFISYYLQY-DFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1366
Cdd:cd11304     4 VSVPENAPPGTvVLTVSATDPDSGENGEVTYSIVSgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|....*
gi 513174004 1367 ASLALSIAVEDVNDN 1381
Cdd:cd11304    84 STATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1701-1792 4.56e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 86.98  E-value: 4.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1701 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGDGTK-FRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPeKKR 1778
Cdd:cd11304     6 VPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGGGP-PLS 83

                          90
                  ....*....|....
gi 513174004 1779 GYCTVVVKITDVND 1792
Cdd:cd11304    84 STATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 458-549 7.16e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.52  E-value: 7.16e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  458 QYEQVIFINMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGG 537
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|..
gi 513174004  538 TNPRSSSVPVHI 549
Cdd:cd11304    79 GPPLSSTATVTI 90
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 355-450 1.09e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  355 SYNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLTP--ADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHL 430
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEvTYSIVSgnEDGLFSIDPStGEITTAKP--LDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 513174004  431 SPYDEAQSAINVLLLDENDN 450
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1186-1277 1.73e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.75  E-value: 1.73e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1186 YEFNIPEEEPVRTVVGSVKA--LTGSIAIQVVYFLRSHTD--KFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPP 1260
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSAtdPDSGENGEVTYSIVSGNEdgLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 513174004 1261 NTAIALVTVIVNDINDN 1277
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1915-1998 4.09e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.51  E-value: 4.09e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1915 PVGVHVITVHATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAV 1991
Cdd:cd11304    11 PPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI--DPSTGEITTAKPLDR-EEQSsytLTVTATDGGGPPLSSTAT 87


                  ....*..
gi 513174004 1992 ITLNVID 1998
Cdd:cd11304    88 VTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1490-1586 1.41e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1490 SYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGL 1569
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGGG 79

                          90
                  ....*....|....*..
gi 513174004 1570 PPLSTSVKVSVTIAPTN 1586
Cdd:cd11304    80 PPLSSTATVTITVLDVN 96
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 142-233 1.89e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  142 YNTSVSEVSAINSTVIKVEAQDKDlSPLFSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 220
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....
gi 513174004  221 -NSNTVSLIIDVQD 233
Cdd:cd11304    81 pLSSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1079-1174 3.80e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.81  E-value: 3.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1079 HYAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHG 1156
Cdd:cd11304     1 SYEVSVP-ENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGG 78

                          90
                  ....*....|....*....
gi 513174004 1157 VPPLASNASVAVCLL-VND 1174
Cdd:cd11304    79 GPPLSSTATVTITVLdVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 245-347 6.39e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.35  E-value: 6.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  245 VYNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAA 324
Cdd:cd11304     1 SYEVSVPENAPPGTVVL--TVSATDPDSGENGEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTAT 75

                          90       100
                  ....*....|....*....|...
gi 513174004  325 QQDNNLKTADAVVLVTIEDVNDN 347
Cdd:cd11304    76 DGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2012-2112 5.03e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.03  E-value: 5.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 2012 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2088
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdpdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTA----TDGG 78

                          90       100
                  ....*....|....*....|....
gi 513174004 2089 QVPSSGlfaqnVAMLTITVQDVNE 2112
Cdd:cd11304    79 GPPLSS-----TATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1600-1687 1.59e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 68.49  E-value: 1.59e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1600 APLSEKTLPDTFVVQITVL-----YKVPVVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIF 1673
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATdpdsgENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEqSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|....
gi 513174004 1674 NDVSVHVEVIDEND 1687
Cdd:cd11304    84 STATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2121-2208 3.06e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.64  E-value: 3.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 2121 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2196
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDReEQSSYtLTVTATDGGGPP 81

                          90
                  ....*....|..
gi 513174004 2197 AHTTVNATIYVT 2208
Cdd:cd11304    82 LSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 603-654 1.39e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


:

Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 53.89  E-value: 1.39e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 513174004    603 FDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT---TDYATVFIQVTDVNDNSP 654
Cdd:smart00112   26 FSIDpETGEITTTKPLDREEQPEYTLTVEATDGGGpplSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 889-966 3.96e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


:

Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 52.35  E-value: 3.96e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    889 SVTDDDEAGFSQGHFI----HNSTFFTVD-IPGIISLRNdtELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVND 963
Cdd:smart00112    1 SATDADSGENGKVTYSilsgNDDGLFSIDpETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 513174004    964 NNP 966
Cdd:smart00112   79 NAP 81
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 763-862 3.66e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.18  E-value: 3.66e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  763 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 842
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNE---DGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 513174004  843 QPSLNTSTHVVIHVLDVNDN 862
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 662-754 4.04e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.54  E-value: 4.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  662 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRL 738
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPsTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 513174004  739 SAVLNLTVVIDDVNDN 754
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1390-1481 1.91e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.61  E-value: 1.91e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1390 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1465
Cdd:cd11304     2 YEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEdglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*.
gi 513174004 1466 LQDTTNITVIVEDVNE 1481
Cdd:cd11304    82 LSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 972-1071 2.23e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.61  E-value: 2.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  972 SYSFAVLEGdyrLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDN 1050
Cdd:cd11304     1 SYEVSVPEN---APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 513174004 1051 GMPRRQNFTYISIQVLDVNDN 1071
Cdd:cd11304    78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1803-1897 8.21e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 8.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1803 FSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGG-NIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFy 1881
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL- 82

                          90
                  ....*....|....*.
gi 513174004 1882 QATTNVTVLVIDVNDN 1897
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1289-1381 8.79e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 8.79e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1289 LSLPENMAPLD-LGTFSATDLDIGDNAFISYYLQY-DFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1366
Cdd:cd11304     4 VSVPENAPPGTvVLTVSATDPDSGENGEVTYSIVSgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|....*
gi 513174004 1367 ASLALSIAVEDVNDN 1381
Cdd:cd11304    84 STATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 781-864 3.49e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.72  E-value: 3.49e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    781 SATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQPSLNTSTHVVIHVLDVN 860
Cdd:smart00112    1 SATDADSGENGKVTYSILSGND---DGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 513174004    861 DNPP 864
Cdd:smart00112   78 DNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1701-1792 4.56e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 86.98  E-value: 4.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1701 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGDGTK-FRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPeKKR 1778
Cdd:cd11304     6 VPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGGGP-PLS 83

                          90
                  ....*....|....
gi 513174004 1779 GYCTVVVKITDVND 1792
Cdd:cd11304    84 STATVTITVLDVND 97
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 994-1073 5.38e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.25  E-value: 5.38e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    994 TATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDNGMPRRQNFTYISIQVLDVNDNV 1072
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 513174004   1073 P 1073
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1304-1383 1.21e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 85.09  E-value: 1.21e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1304 SATDLDIGDNAFISYYLQYDFA-GMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLSASLALSIAVEDVNDNS 1382
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 513174004   1383 P 1383
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 458-549 7.16e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.52  E-value: 7.16e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  458 QYEQVIFINMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGG 537
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|..
gi 513174004  538 TNPRSSSVPVHI 549
Cdd:cd11304    79 GPPLSSTATVTI 90
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 680-756 9.43e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 82.78  E-value: 9.43e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    680 ATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPP 756
Cdd:smart00112    2 ATDADSGENGKVTYSILSgnDDGLFSIDPeTGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 355-450 1.09e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  355 SYNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLTP--ADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHL 430
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEvTYSIVSgnEDGLFSIDPStGEITTAKP--LDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 513174004  431 SPYDEAQSAINVLLLDENDN 450
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1186-1277 1.73e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.75  E-value: 1.73e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1186 YEFNIPEEEPVRTVVGSVKA--LTGSIAIQVVYFLRSHTD--KFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPP 1260
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSAtdPDSGENGEVTYSIVSGNEdgLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 513174004 1261 NTAIALVTVIVNDINDN 1277
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
763-857 7.03e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.81  E-value: 7.03e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   763 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 842
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGP---GGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 513174004   843 QPSLNTSTHVVIHVL 857
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1390-1477 1.20e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.04  E-value: 1.20e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1390 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1465
Cdd:pfam00028    1 YSASVPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGPggnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 513174004  1466 LQDTTNITVIVE 1477
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1715-1795 2.77e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.55  E-value: 2.77e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1715 ARDNDTGRNGDLTYGILSG-DGTKFRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPEkKRGYCTVVVKITDVNDW 1793
Cdd:smart00112    2 ATDADSGENGKVTYSILSGnDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGPP-LSSTATVTITVLDVNDN 79


                    ..
gi 513174004   1794 PP 1795
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1407-1484 3.17e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.55  E-value: 3.17e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1407 TATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDVNEEG 1483
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdglFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 513174004   1484 P 1484
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1915-1998 4.09e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.51  E-value: 4.09e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1915 PVGVHVITVHATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAV 1991
Cdd:cd11304    11 PPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI--DPSTGEITTAKPLDR-EEQSsytLTVTATDGGGPPLSSTAT 87


                  ....*..
gi 513174004 1992 ITLNVID 1998
Cdd:cd11304    88 VTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1490-1586 1.41e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1490 SYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGL 1569
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGGG 79

                          90
                  ....*....|....*..
gi 513174004 1570 PPLSTSVKVSVTIAPTN 1586
Cdd:cd11304    80 PPLSSTATVTITVLDVN 96
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 142-233 1.89e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  142 YNTSVSEVSAINSTVIKVEAQDKDlSPLFSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 220
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....
gi 513174004  221 -NSNTVSLIIDVQD 233
Cdd:cd11304    81 pLSSTATVTITVLD 94
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1819-1899 2.29e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 75.85  E-value: 2.29e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1819 TAMDRDTGDNAFVLYSLTGGG-GNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNkSAPFYQATTNVTVLVIDVNDN 1897
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNdDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDN 79


                    ..
gi 513174004   1898 AP 1899
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1079-1174 3.80e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.81  E-value: 3.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1079 HYAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHG 1156
Cdd:cd11304     1 SYEVSVP-ENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGG 78

                          90
                  ....*....|....*....
gi 513174004 1157 VPPLASNASVAVCLL-VND 1174
Cdd:cd11304    79 GPPLSSTATVTITVLdVND 97
Cadherin pfam00028
Cadherin domain;
662-748 7.10e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.03  E-value: 7.10e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   662 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLK--GAEGKMDID-ASGLILLKKELDRETQGIYNLAVIASDQGQPRL 738
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|
gi 513174004   739 SAVLNLTVVI 748
Cdd:pfam00028   82 SSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1290-1376 2.22e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 73.49  E-value: 2.22e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1290 SLPENmAPLD--LGTFSATDLDIGDNAFISYYLQYDF-AGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1366
Cdd:pfam00028    4 SVPEN-APVGteVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82

                           90
                   ....*....|
gi 513174004  1367 ASLALSIAVE 1376
Cdd:pfam00028   83 STATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 245-347 6.39e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.35  E-value: 6.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  245 VYNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAA 324
Cdd:cd11304     1 SYEVSVPENAPPGTVVL--TVSATDPDSGENGEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTAT 75

                          90       100
                  ....*....|....*....|...
gi 513174004  325 QQDNNLKTADAVVLVTIEDVNDN 347
Cdd:cd11304    76 DGGGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
973-1066 3.36e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.02  E-value: 3.36e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   973 YSFAVLEGDyRLGAPavVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDNG 1051
Cdd:pfam00028    1 YSASVPENA-PVGTE--VLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 513174004  1052 MPRRQNFTYISIQVL 1066
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2012-2112 5.03e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.03  E-value: 5.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 2012 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2088
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdpdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTA----TDGG 78

                          90       100
                  ....*....|....*....|....
gi 513174004 2089 QVPSSGlfaqnVAMLTITVQDVNE 2112
Cdd:cd11304    79 GPPLSS-----TATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
1802-1892 5.57e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 5.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1802 PFSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGG-GNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPF 1880
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|..
gi 513174004  1881 YQaTTNVTVLVI 1892
Cdd:pfam00028   82 SS-TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1600-1687 1.59e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 68.49  E-value: 1.59e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1600 APLSEKTLPDTFVVQITVL-----YKVPVVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIF 1673
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATdpdsgENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEqSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|....
gi 513174004 1674 NDVSVHVEVIDEND 1687
Cdd:cd11304    84 STATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
466-549 1.85e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.10  E-value: 1.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   466 NMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGGTNPRSSSV 545
Cdd:pfam00028    8 NAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTK--PLDRESIGEYELTVEATDSGGPPLSSTA 85


                   ....
gi 513174004   546 PVHI 549
Cdd:pfam00028   86 TVTI 89
Cadherin pfam00028
Cadherin domain;
1701-1788 2.73e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 67.71  E-value: 2.73e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1701 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGD-GTKFRIDESTGILYSTVSFDYeEEPTEYQVVIYAEDDGTPeKKR 1778
Cdd:pfam00028    5 VPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDR-ESIGEYELTVEATDSGGP-PLS 82

                           90
                   ....*....|
gi 513174004  1779 GYCTVVVKIT 1788
Cdd:pfam00028   83 STATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1213-1279 3.67e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 3.67e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1213 QVVYFL--RSHTDKFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPP 1279
Cdd:smart00112   12 KVTYSIlsGNDDGLFSIdPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 478-549 9.55e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.83  E-value: 9.55e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 513174004    478 ADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGGTNPRSSSVPVHI 549
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTI 71
Cadherin pfam00028
Cadherin domain;
1498-1582 1.74e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 1.74e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1498 NSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGLPPLSTSVK 1577
Cdd:pfam00028    8 NAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYE-LTVEATDSGGPPLSSTAT 86


                   ....*
gi 513174004  1578 VSVTI 1582
Cdd:pfam00028   87 VTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2121-2208 3.06e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.64  E-value: 3.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 2121 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2196
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDReEQSSYtLTVTATDGGGPP 81

                          90
                  ....*....|..
gi 513174004 2197 AHTTVNATIYVT 2208
Cdd:cd11304    82 LSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1623-1690 4.25e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 63.91  E-value: 4.25e-12
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 513174004   1623 VVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPP 1690
Cdd:smart00112   13 VTYSILSGNDDGLFSIDPETGEITTTKPLDREEqPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
1915-1997 4.60e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.24  E-value: 4.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1915 PVGVHVITVHATDKDQGQNGLIEYYIIPDlNFSAFFLIEDESeGKIITTGNLSRFE--EVCLTVMAKDKGSPSLNSTAVI 1992
Cdd:pfam00028   10 PVGTEVLTVTATDPDLGPNGRIFYSILGG-GPGGNFRIDPDT-GDISTTKPLDRESigEYELTVEATDSGGPPLSSTATV 87


                   ....*
gi 513174004  1993 TLNVI 1997
Cdd:pfam00028   88 TITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 267-349 1.13e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 62.75  E-value: 1.13e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    267 AKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVND 346
Cdd:smart00112    2 ATDADSGENGKVTYSIL---SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 513174004    347 NLP 349
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2038-2114 2.58e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 2.58e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 513174004   2038 IVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAAQVPSSGlfaqnVAMLTITVQDVNEKP 2114
Cdd:smart00112   13 VTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEA----TDGGGPPLSS-----TATVTITVLDVNDNA 80
Cadherin pfam00028
Cadherin domain;
2012-2108 3.02e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.93  E-value: 3.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  2012 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2088
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATdpdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA----TDSG 77

                           90       100
                   ....*....|....*....|
gi 513174004  2089 QVPSSGlfaqnVAMLTITVQ 2108
Cdd:pfam00028   78 GPPLSS-----TATVTITVL 92
Cadherin pfam00028
Cadherin domain;
142-232 5.11e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.16  E-value: 5.11e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   142 YNTSVSEVSAINSTVIKVEAQDKDLSPLfSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 220
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPN-GRIFYSILGGGPGgNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 513174004   221 N-SNTVSLIIDVQ 232
Cdd:pfam00028   80 PlSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1186-1271 7.18e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.78  E-value: 7.18e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1186 YEFNIPEEEPVRTVVGSVKAL---TGSIAiQVVYFLRSHT--DKFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVP 1259
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdpdLGPNG-RIFYSILGGGpgGNFRIdPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 513174004  1260 PNTAIALVTVIV 1271
Cdd:pfam00028   80 PLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1099-1174 7.27e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.44  E-value: 7.27e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 513174004   1099 SATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHGVPPLASNASVAVCLL-VND 1174
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGPPLSSTATVTITVLdVND 78
Cadherin pfam00028
Cadherin domain;
1080-1168 8.65e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.39  E-value: 8.65e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1080 YAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLMNH--SDIFHINNHTGEIILLSSLAHVTADMvVTLTVIAADHGV 1157
Cdd:pfam00028    1 YSASVP-ENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgpGGNFRIDPDTGDISTTKPLDRESIGE-YELTVEATDSGG 78

                           90
                   ....*....|.
gi 513174004  1158 PPLASNASVAV 1168
Cdd:pfam00028   79 PPLSSTATVTI 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1924-2001 1.29e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.67  E-value: 1.29e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1924 HATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAVITLNVID-- 1998
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSI--DPETGEITTTKPLDR-EEQPeytLTVEATDGGGPPLSSTATVTITVLDvn 77


                    ....
gi 513174004   1999 -NRP 2001
Cdd:smart00112   78 dNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 375-452 1.43e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.29  E-value: 1.43e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    375 AVDKDEGGFQG-TFSLTP--ADSPFQI-SQDGILTVRNStlLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDN 450
Cdd:smart00112    2 ATDADSGENGKvTYSILSgnDDGLFSIdPETGEITTTKP--LDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 513174004    451 NP 452
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1510-1582 1.60e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.29  E-value: 1.60e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 513174004   1510 ARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGLPPLSTSVKVSVTI 1582
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSSTATVTITV 73
Cadherin pfam00028
Cadherin domain;
2121-2208 1.29e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 57.31  E-value: 1.29e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  2121 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLLNHQE--QFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2196
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPggNFRIDPDTGDISTTKPLDReSIGEYeLTVEATDSGGPP 80

                           90
                   ....*....|..
gi 513174004  2197 AHTTVNATIYVT 2208
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
356-445 3.62e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 55.77  E-value: 3.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   356 YNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLT--PADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHLS 431
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRiFYSILggGPGGNFRIDPDtGDISTTKP--LDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|....
gi 513174004   432 PYDEAQSAINVLLL 445
Cdd:pfam00028   79 PPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 603-654 1.39e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 53.89  E-value: 1.39e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 513174004    603 FDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT---TDYATVFIQVTDVNDNSP 654
Cdd:smart00112   26 FSIDpETGEITTTKPLDREEQPEYTLTVEATDGGGpplSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 889-966 3.96e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 52.35  E-value: 3.96e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    889 SVTDDDEAGFSQGHFI----HNSTFFTVD-IPGIISLRNdtELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVND 963
Cdd:smart00112    1 SATDADSGENGKVTYSilsgNDDGLFSIDpETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 513174004    964 NNP 966
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 161-233 8.65e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 51.58  E-value: 8.65e-08
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 513174004    161 AQDKDlSPLFSHISYSLLGPN-SDYFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGNN-SNTVSLIIDVQD 233
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNdDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPlSSTATVTITVLD 75
Cadherin pfam00028
Cadherin domain;
1598-1683 1.21e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 51.53  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1598 QPAPLSEKTLPDTFVVQITVL-YKVP----VVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTAS 1671
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdPDLGpngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESiGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 513174004  1672 IFNDVSVHVEVI 1683
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2139-2208 7.96e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 48.89  E-value: 7.96e-07
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 513174004   2139 QATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLTAHTTVNATIYVT 2208
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDReEQPEYtLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
246-342 5.10e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 46.91  E-value: 5.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   246 YNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAaq 325
Cdd:pfam00028    1 YSASVPENAPVGTEVL--TVTATDPDLGPNGRIFYSIL---GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA-- 73

                           90
                   ....*....|....*..
gi 513174004   326 QDNNLKTADAVVLVTIE 342
Cdd:pfam00028   74 TDSGGPPLSSTATVTIT 90
Cadherin pfam00028
Cadherin domain;
564-647 1.96e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.29  E-value: 1.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   564 YNVSVEEELVSPVEVARVKY--ESLNPHIPVILRVLT--ESATFDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT-- 636
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTAtdPDLGPNGRIFYSILGggPGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGpp 80

                           90
                   ....*....|..
gi 513174004   637 -TDYATVFIQVT 647
Cdd:pfam00028   81 lSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
871-959 1.98e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.29  E-value: 1.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   871 YDIVVFENIQKGSPVCTFSVTDDDEAG-------FSQGHFIHNstfFTVD-IPGIISLRndTELDRETTPGFTLQVWAVD 942
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngrifysILGGGPGGN---FRIDpDTGDISTT--KPLDRESIGEYELTVEATD 75

                           90
                   ....*....|....*..
gi 513174004   943 AEKDGLNSSSLFHITVL 959
Cdd:pfam00028   76 SGGPPLSSTATVTITVL 92
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 763-862 3.66e-29

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 113.18  E-value: 3.66e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  763 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 842
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNE---DGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 513174004  843 QPSLNTSTHVVIHVLDVNDN 862
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 662-754 4.04e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.54  E-value: 4.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  662 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRL 738
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSgnEDGLFSIDPsTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 513174004  739 SAVLNLTVVIDDVNDN 754
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1390-1481 1.91e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.61  E-value: 1.91e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1390 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1465
Cdd:cd11304     2 YEVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEdglFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*.
gi 513174004 1466 LQDTTNITVIVEDVNE 1481
Cdd:cd11304    82 LSSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 972-1071 2.23e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.61  E-value: 2.23e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  972 SYSFAVLEGdyrLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDN 1050
Cdd:cd11304     1 SYEVSVPEN---APPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPStGEITTAKPLDREEQSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 513174004 1051 GMPRRQNFTYISIQVLDVNDN 1071
Cdd:cd11304    78 GGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1803-1897 8.21e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.07  E-value: 8.21e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1803 FSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGG-NIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFy 1881
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL- 82

                          90
                  ....*....|....*.
gi 513174004 1882 QATTNVTVLVIDVNDN 1897
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1289-1381 8.79e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 8.79e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1289 LSLPENMAPLD-LGTFSATDLDIGDNAFISYYLQY-DFAGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1366
Cdd:cd11304     4 VSVPENAPPGTvVLTVSATDPDSGENGEVTYSIVSgNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|....*
gi 513174004 1367 ASLALSIAVEDVNDN 1381
Cdd:cd11304    84 STATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 781-864 3.49e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.72  E-value: 3.49e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    781 SATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQPSLNTSTHVVIHVLDVN 860
Cdd:smart00112    1 SATDADSGENGKVTYSILSGND---DGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 513174004    861 DNPP 864
Cdd:smart00112   78 DNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1701-1792 4.56e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 86.98  E-value: 4.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1701 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGDGTK-FRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPeKKR 1778
Cdd:cd11304     6 VPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGlFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGGGP-PLS 83

                          90
                  ....*....|....
gi 513174004 1779 GYCTVVVKITDVND 1792
Cdd:cd11304    84 STATVTITVLDVND 97
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 994-1073 5.38e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.25  E-value: 5.38e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    994 TATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDNGMPRRQNFTYISIQVLDVNDNV 1072
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPEtGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 513174004   1073 P 1073
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1304-1383 1.21e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 85.09  E-value: 1.21e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1304 SATDLDIGDNAFISYYLQYDFA-GMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLSASLALSIAVEDVNDNS 1382
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 513174004   1383 P 1383
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 458-549 7.16e-19

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.52  E-value: 7.16e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  458 QYEQVIFINMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGG 537
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAK--PLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|..
gi 513174004  538 TNPRSSSVPVHI 549
Cdd:cd11304    79 GPPLSSTATVTI 90
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 680-756 9.43e-19

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 82.78  E-value: 9.43e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    680 ATDVDTGFNGLVVYTLKG--AEGKMDIDA-SGLILLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPP 756
Cdd:smart00112    2 ATDADSGENGKVTYSILSgnDDGLFSIDPeTGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 355-450 1.09e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  355 SYNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLTP--ADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHL 430
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEvTYSIVSgnEDGLFSIDPStGEITTAKP--LDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 513174004  431 SPYDEAQSAINVLLLDENDN 450
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1186-1277 1.73e-18

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 82.75  E-value: 1.73e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1186 YEFNIPEEEPVRTVVGSVKA--LTGSIAIQVVYFLRSHTD--KFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPP 1260
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSAtdPDSGENGEVTYSIVSGNEdgLFSIdPSTGEITTAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 513174004 1261 NTAIALVTVIVNDINDN 1277
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
763-857 7.03e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.81  E-value: 7.03e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   763 YEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPltsSPVFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGG 842
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGP---GGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 513174004   843 QPSLNTSTHVVIHVL 857
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1390-1477 1.20e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.04  E-value: 1.20e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1390 YSVTVKENDPP-HVILSTTATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPH 1465
Cdd:pfam00028    1 YSASVPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGPggnFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 513174004  1466 LQDTTNITVIVE 1477
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1715-1795 2.77e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.55  E-value: 2.77e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1715 ARDNDTGRNGDLTYGILSG-DGTKFRIDESTGILYSTVSFDYEEEPtEYQVVIYAEDDGTPEkKRGYCTVVVKITDVNDW 1793
Cdd:smart00112    2 ATDADSGENGKVTYSILSGnDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGPP-LSSTATVTITVLDVNDN 79


                    ..
gi 513174004   1794 PP 1795
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1407-1484 3.17e-17

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 78.55  E-value: 3.17e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1407 TATDKDIGYNAVIQYTIIGETS---FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDVNEEG 1483
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdglFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 513174004   1484 P 1484
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1915-1998 4.09e-17

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 78.51  E-value: 4.09e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1915 PVGVHVITVHATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAV 1991
Cdd:cd11304    11 PPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSI--DPSTGEITTAKPLDR-EEQSsytLTVTATDGGGPPLSSTAT 87


                  ....*..
gi 513174004 1992 ITLNVID 1998
Cdd:cd11304    88 VTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1490-1586 1.41e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1490 SYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGL 1569
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYT-LTVTATDGGG 79

                          90
                  ....*....|....*..
gi 513174004 1570 PPLSTSVKVSVTIAPTN 1586
Cdd:cd11304    80 PPLSSTATVTITVLDVN 96
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 142-233 1.89e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 76.97  E-value: 1.89e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  142 YNTSVSEVSAINSTVIKVEAQDKDlSPLFSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 220
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDgLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....
gi 513174004  221 -NSNTVSLIIDVQD 233
Cdd:cd11304    81 pLSSTATVTITVLD 94
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1819-1899 2.29e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 75.85  E-value: 2.29e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1819 TAMDRDTGDNAFVLYSLTGGG-GNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNkSAPFYQATTNVTVLVIDVNDN 1897
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNdDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDN 79


                    ..
gi 513174004   1898 AP 1899
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1079-1174 3.80e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 75.81  E-value: 3.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1079 HYAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHG 1156
Cdd:cd11304     1 SYEVSVP-ENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDREEQS-SYTLTVTATDGG 78

                          90
                  ....*....|....*....
gi 513174004 1157 VPPLASNASVAVCLL-VND 1174
Cdd:cd11304    79 GPPLSSTATVTITVLdVND 97
Cadherin pfam00028
Cadherin domain;
662-748 7.10e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.03  E-value: 7.10e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   662 TIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLK--GAEGKMDID-ASGLILLKKELDRETQGIYNLAVIASDQGQPRL 738
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILggGPGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|
gi 513174004   739 SAVLNLTVVI 748
Cdd:pfam00028   82 SSTATVTITV 91
Cadherin pfam00028
Cadherin domain;
1290-1376 2.22e-15

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 73.49  E-value: 2.22e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1290 SLPENmAPLD--LGTFSATDLDIGDNAFISYYLQYDF-AGMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPPLS 1366
Cdd:pfam00028    4 SVPEN-APVGteVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82

                           90
                   ....*....|
gi 513174004  1367 ASLALSIAVE 1376
Cdd:pfam00028   83 STATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 245-347 6.39e-15

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 72.35  E-value: 6.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  245 VYNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAA 324
Cdd:cd11304     1 SYEVSVPENAPPGTVVL--TVSATDPDSGENGEVTYSIV---SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTAT 75

                          90       100
                  ....*....|....*....|...
gi 513174004  325 QQDNNLKTADAVVLVTIEDVNDN 347
Cdd:cd11304    76 DGGGPPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
973-1066 3.36e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.02  E-value: 3.36e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   973 YSFAVLEGDyRLGAPavVGHVTATDLDEGENARITYYLSSEDGDNPYDIQQD-GTILVNGCVDRETKEKYELLLVASDNG 1051
Cdd:pfam00028    1 YSASVPENA-PVGTE--VLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDtGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 513174004  1052 MPRRQNFTYISIQVL 1066
Cdd:pfam00028   78 GPPLSSTATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2012-2112 5.03e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.03  E-value: 5.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 2012 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2088
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdpdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTA----TDGG 78

                          90       100
                  ....*....|....*....|....
gi 513174004 2089 QVPSSGlfaqnVAMLTITVQDVNE 2112
Cdd:cd11304    79 GPPLSS-----TATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
1802-1892 5.57e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 5.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1802 PFSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGG-GNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPF 1880
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|..
gi 513174004  1881 YQaTTNVTVLVI 1892
Cdd:pfam00028   82 SS-TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1600-1687 1.59e-13

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 68.49  E-value: 1.59e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 1600 APLSEKTLPDTFVVQITVL-----YKVPVVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIF 1673
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATdpdsgENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEqSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|....
gi 513174004 1674 NDVSVHVEVIDEND 1687
Cdd:cd11304    84 STATVTITVLDVND 97
Cadherin pfam00028
Cadherin domain;
466-549 1.85e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.10  E-value: 1.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   466 NMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGGTNPRSSSV 545
Cdd:pfam00028    8 NAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTK--PLDRESIGEYELTVEATDSGGPPLSSTA 85


                   ....
gi 513174004   546 PVHI 549
Cdd:pfam00028   86 TVTI 89
Cadherin pfam00028
Cadherin domain;
1701-1788 2.73e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 67.71  E-value: 2.73e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1701 LEENLPA-TQIVHLIARDNDTGRNGDLTYGILSGD-GTKFRIDESTGILYSTVSFDYeEEPTEYQVVIYAEDDGTPeKKR 1778
Cdd:pfam00028    5 VPENAPVgTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDR-ESIGEYELTVEATDSGGP-PLS 82

                           90
                   ....*....|
gi 513174004  1779 GYCTVVVKIT 1788
Cdd:pfam00028   83 STATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1213-1279 3.67e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 66.99  E-value: 3.67e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1213 QVVYFL--RSHTDKFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPP 1279
Cdd:smart00112   12 KVTYSIlsGNDDGLFSIdPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 478-549 9.55e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.83  E-value: 9.55e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 513174004    478 ADDPDDGINGAISFVLAGGNEDGYFELDKSTGQISLKAviPLRVNESKNFVLWVTATDGGTNPRSSSVPVHI 549
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTI 71
Cadherin pfam00028
Cadherin domain;
1498-1582 1.74e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 1.74e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1498 NSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGLPPLSTSVK 1577
Cdd:pfam00028    8 NAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYE-LTVEATDSGGPPLSSTAT 86


                   ....*
gi 513174004  1578 VSVTI 1582
Cdd:pfam00028   87 VTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2121-2208 3.06e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 64.64  E-value: 3.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004 2121 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2196
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsgNEDGLFSIDPSTGEITTAKPLDReEQSSYtLTVTATDGGGPP 81

                          90
                  ....*....|..
gi 513174004 2197 AHTTVNATIYVT 2208
Cdd:cd11304    82 LSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1623-1690 4.25e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 63.91  E-value: 4.25e-12
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 513174004   1623 VVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPP 1690
Cdd:smart00112   13 VTYSILSGNDDGLFSIDPETGEITTTKPLDREEqPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
1915-1997 4.60e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.24  E-value: 4.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1915 PVGVHVITVHATDKDQGQNGLIEYYIIPDlNFSAFFLIEDESeGKIITTGNLSRFE--EVCLTVMAKDKGSPSLNSTAVI 1992
Cdd:pfam00028   10 PVGTEVLTVTATDPDLGPNGRIFYSILGG-GPGGNFRIDPDT-GDISTTKPLDRESigEYELTVEATDSGGPPLSSTATV 87


                   ....*
gi 513174004  1993 TLNVI 1997
Cdd:pfam00028   88 TITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 267-349 1.13e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 62.75  E-value: 1.13e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    267 AKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVND 346
Cdd:smart00112    2 ATDADSGENGKVTYSIL---SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 513174004    347 NLP 349
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2038-2114 2.58e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 61.60  E-value: 2.58e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 513174004   2038 IVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAAQVPSSGlfaqnVAMLTITVQDVNEKP 2114
Cdd:smart00112   13 VTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEA----TDGGGPPLSS-----TATVTITVLDVNDNA 80
Cadherin pfam00028
Cadherin domain;
2012-2108 3.02e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.93  E-value: 3.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  2012 SISVLENTGVDHSIYTFAVA---ETSGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEAnedvSSAA 2088
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATdpdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA----TDSG 77

                           90       100
                   ....*....|....*....|
gi 513174004  2089 QVPSSGlfaqnVAMLTITVQ 2108
Cdd:pfam00028   78 GPPLSS-----TATVTITVL 92
Cadherin pfam00028
Cadherin domain;
142-232 5.11e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 61.16  E-value: 5.11e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   142 YNTSVSEVSAINSTVIKVEAQDKDLSPLfSHISYSLLGPNSD-YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN 220
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPN-GRIFYSILGGGPGgNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 513174004   221 N-SNTVSLIIDVQ 232
Cdd:pfam00028   80 PlSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1186-1271 7.18e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.78  E-value: 7.18e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1186 YEFNIPEEEPVRTVVGSVKAL---TGSIAiQVVYFLRSHT--DKFAI-SDQGDIVTLATLDREDDNLYNIVVEAVDSVVP 1259
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdpdLGPNG-RIFYSILGGGpgGNFRIdPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|..
gi 513174004  1260 PNTAIALVTVIV 1271
Cdd:pfam00028   80 PLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1099-1174 7.27e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.44  E-value: 7.27e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 513174004   1099 SATDLDIGNNSVISYSLM--NHSDIFHINNHTGEIILLSSLAHVTADmVVTLTVIAADHGVPPLASNASVAVCLL-VND 1174
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGPPLSSTATVTITVLdVND 78
Cadherin pfam00028
Cadherin domain;
1080-1168 8.65e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.39  E-value: 8.65e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1080 YAASIPvATAKEGAFVLSVSATDLDIGNNSVISYSLMNH--SDIFHINNHTGEIILLSSLAHVTADMvVTLTVIAADHGV 1157
Cdd:pfam00028    1 YSASVP-ENAPVGTEVLTVTATDPDLGPNGRIFYSILGGgpGGNFRIDPDTGDISTTKPLDRESIGE-YELTVEATDSGG 78

                           90
                   ....*....|.
gi 513174004  1158 PPLASNASVAV 1168
Cdd:pfam00028   79 PPLSSTATVTI 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1924-2001 1.29e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.67  E-value: 1.29e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   1924 HATDKDQGQNGLIEYYIIPDLNFSAFFLieDESEGKIITTGNLSRfEEVC---LTVMAKDKGSPSLNSTAVITLNVID-- 1998
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSI--DPETGEITTTKPLDR-EEQPeytLTVEATDGGGPPLSSTATVTITVLDvn 77


                    ....
gi 513174004   1999 -NRP 2001
Cdd:smart00112   78 dNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 375-452 1.43e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.29  E-value: 1.43e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    375 AVDKDEGGFQG-TFSLTP--ADSPFQI-SQDGILTVRNStlLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDN 450
Cdd:smart00112    2 ATDADSGENGKvTYSILSgnDDGLFSIdPETGEITTTKP--LDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 513174004    451 NP 452
Cdd:smart00112   80 AP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1510-1582 1.60e-10

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 59.29  E-value: 1.60e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 513174004   1510 ARDESKGYDEGIFYNITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNsLTVTATDSGLPPLSTSVKVSVTI 1582
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSSTATVTITV 73
Cadherin pfam00028
Cadherin domain;
2121-2208 1.29e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 57.31  E-value: 1.29e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  2121 YSALIPSSVPYKYPVITVQATDPDAGGNGLLTYSLLNHQE--QFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLT 2196
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPggNFRIDPDTGDISTTKPLDReSIGEYeLTVEATDSGGPP 80

                           90
                   ....*....|..
gi 513174004  2197 AHTTVNATIYVT 2208
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
356-445 3.62e-09

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 55.77  E-value: 3.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   356 YNVSILENFPNGKEVLRIEAVDKDEGGFQG-TFSLT--PADSPFQISQD-GILTVRNStlLDREQTPSIHLQVTARDHLS 431
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRiFYSILggGPGGNFRIDPDtGDISTTKP--LDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|....
gi 513174004   432 PYDEAQSAINVLLL 445
Cdd:pfam00028   79 PPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 603-654 1.39e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 53.89  E-value: 1.39e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 513174004    603 FDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT---TDYATVFIQVTDVNDNSP 654
Cdd:smart00112   26 FSIDpETGEITTTKPLDREEQPEYTLTVEATDGGGpplSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 889-966 3.96e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 52.35  E-value: 3.96e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004    889 SVTDDDEAGFSQGHFI----HNSTFFTVD-IPGIISLRNdtELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVND 963
Cdd:smart00112    1 SATDADSGENGKVTYSilsgNDDGLFSIDpETGEITTTK--PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVND 78


                    ...
gi 513174004    964 NNP 966
Cdd:smart00112   79 NAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 161-233 8.65e-08

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 51.58  E-value: 8.65e-08
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 513174004    161 AQDKDlSPLFSHISYSLLGPN-SDYFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGNN-SNTVSLIIDVQD 233
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNdDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPlSSTATVTITVLD 75
Cadherin pfam00028
Cadherin domain;
1598-1683 1.21e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 51.53  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004  1598 QPAPLSEKTLPDTFVVQITVL-YKVP----VVYSIVAGDEKGYFIINPSTGTIRTGKKLTVED-SLIVFSVRATDSSTAS 1671
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATdPDLGpngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESiGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 513174004  1672 IFNDVSVHVEVI 1683
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2139-2208 7.96e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 48.89  E-value: 7.96e-07
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 513174004   2139 QATDPDAGGNGLLTYSLL--NHQEQFDVNENTGQIYTVSVVGY-SGPIF-LGLQAADQGGLTAHTTVNATIYVT 2208
Cdd:smart00112    1 SATDADSGENGKVTYSILsgNDDGLFSIDPETGEITTTKPLDReEQPEYtLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
246-342 5.10e-06

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 46.91  E-value: 5.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   246 YNGTISENKLGPLSILpeKIFAKDGDTGINEKVYYSIKlvkPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAaq 325
Cdd:pfam00028    1 YSASVPENAPVGTEVL--TVTATDPDLGPNGRIFYSIL---GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEA-- 73

                           90
                   ....*....|....*..
gi 513174004   326 QDNNLKTADAVVLVTIE 342
Cdd:pfam00028   74 TDSGGPPLSSTATVTIT 90
Cadherin pfam00028
Cadherin domain;
564-647 1.96e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.29  E-value: 1.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   564 YNVSVEEELVSPVEVARVKY--ESLNPHIPVILRVLT--ESATFDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVT-- 636
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTAtdPDLGPNGRIFYSILGggPGGNFRIDpDTGDISTTKPLDRESIGEYELTVEATDSGGpp 80

                           90
                   ....*....|..
gi 513174004   637 -TDYATVFIQVT 647
Cdd:pfam00028   81 lSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
871-959 1.98e-04

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 42.29  E-value: 1.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 513174004   871 YDIVVFENIQKGSPVCTFSVTDDDEAG-------FSQGHFIHNstfFTVD-IPGIISLRndTELDRETTPGFTLQVWAVD 942
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngrifysILGGGPGGN---FRIDpDTGDISTT--KPLDRESIGEYELTVEATD 75

                           90
                   ....*....|....*..
gi 513174004   943 AEKDGLNSSSLFHITVL 959
Cdd:pfam00028   76 SGGPPLSSTATVTITVL 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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