|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
329-657 |
1.97e-26 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 110.89 E-value: 1.97e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 329 RQDITCICFSPSEEVLVVSTTKNQLYMFTMPSADYLKEesshfeylhFPLHSASITGLDVCIRRPIVATCSLDKSVRVWN 408
Cdd:cd00200 9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRT---------LKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 409 YKTNtlelckefwEEAYTVALHPTGLFClvgfsdklrfisllyedmhvfkdfpvrecreCSFSNGGHLFAAVNG-NVIQI 487
Cdd:cd00200 80 LETG---------ECVRTLTGHTSYVSS-------------------------------VAFSPDGRILSSSSRdKTIKV 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 488 YSCTTFENTNNLKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWNLSTGKREMECVL-TSCIYsSIALHSDSKIIFAVGSD 566
Cdd:cd00200 120 WDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGhTGEVN-SVAFSPDGEKLLSSSSD 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 567 QTLK--EISESSVHHEVPAFDVVYTAVAVSHSGDMVFVGTSLGTVRSmkYPLPLCRDFNEYQAHAGAITKMSVTNDDLFL 644
Cdd:cd00200 199 GTIKlwDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRV--WDLRTGECVQTLSGHTNSVTSLAWSPDGKRL 276
|
330
....*....|...
gi 2024426573 645 LTASEDGSIFFWK 657
Cdd:cd00200 277 ASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
394-658 |
4.35e-22 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 100.37 E-value: 4.35e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 394 IVATCSLDKSVRVWNykTNTLELCKEF---WEEAYTVALHPTGLFCLVGFSDK-LRFISLL-YEDMHVFKDfPVRECREC 468
Cdd:COG2319 134 TLASGSADGTVRLWD--LATGKLLRTLtghSGAVTSVAFSPDGKLLASGSDDGtVRLWDLAtGKLLRTLTG-HTGAVRSV 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 469 SFS-NGGHLFAAVNGNVIQIYSCTTFENTNNLKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWNLSTGKREMECVLTSCI 547
Cdd:COG2319 211 AFSpDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGG 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 548 YSSIALHSDSKIIFAVGSDQTLK--EISESSVHHEVPAFDVVYTAVAVSHSGDMVFVGTSLGTVR--SMKYPLPLcrdfN 623
Cdd:COG2319 291 VNSVAFSPDGKLLASGSDDGTVRlwDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRlwDLATGELL----R 366
|
250 260 270
....*....|....*....|....*....|....*
gi 2024426573 624 EYQAHAGAITKMSVTNDDLFLLTASEDGSIFFWKV 658
Cdd:COG2319 367 TLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDL 401
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
660-1168 |
4.42e-20 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 96.63 E-value: 4.42e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 660 SKKGKILKREKEfEYAEEVLIMKSDIEEKSRTILDL--QIRVKELQIENDYQLRLKDMSCYEKIKELEETFTQELESLKN 737
Cdd:TIGR04523 158 NNKYNDLKKQKE-ELENELNLLEKEKLNIQKNIDKIknKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEK 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 738 KHQILQaEKDNQEMQHQLQLSELMNKHAKEMRDLEsDSNQKLLMENEKYQELQVDSQRMQEEyekqlhnLQESKNRTVEE 817
Cdd:TIGR04523 237 KQQEIN-EKTTEISNTQTQLNQLKDEQNKIKKQLS-EKQKELEQNNKKIKELEKQLNQLKSE-------ISDLNNQKEQD 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 818 LTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIE----EDEDREIQDIKIKYErwlIEEKESNLQ-LKGEIGVMNK 892
Cdd:TIGR04523 308 WNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISqlkkELTNSESENSEKQRE---LEEKQNEIEkLKKENQSYKQ 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 893 RLNSLQKELKERNNDIEDMKLEQQNLQGIIKS-------LEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKF 965
Cdd:TIGR04523 385 EIKNLESQINDLESKIQNQEKLNQQKDEQIKKlqqekelLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRE 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 966 VLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQK---LKATDNELHKERQKKqnmEALIK 1042
Cdd:TIGR04523 465 SLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKissLKEKIEKLESEKKEK---ESKIS 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1043 RFKMDLhNCVGFIQDYKKLKAGIRElytkyvQQLEMVEMEEVDTDLQQEyMRQREYLERNLAALKKKVVKDQEVHqaayt 1122
Cdd:TIGR04523 542 DLEDEL-NKDDFELKKENLEKEIDE------KNKEIEELKQTQKSLKKK-QEEKQELIDQKEKEKKDLIKEIEEK----- 608
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 2024426573 1123 riMQENVSLIKEINDLRQELTVAHTQVHDLQSAL-KLTKKKQAIQDT 1168
Cdd:TIGR04523 609 --EKKISSLEKELEKAKKENEKLSSIIKNIKSKKnKLKQEVKQIKET 653
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
375-662 |
1.41e-19 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 90.47 E-value: 1.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 375 HFPLHSASITGLDVCIRRPIVATCSLDKSVRVWNYKTNTLelckefweeaytvalhptgLFCLVGFSDKLRFisllyedm 454
Cdd:cd00200 4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGEL-------------------LRTLKGHTGPVRD-------- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 455 hvfkdfpvrecreCSFSNGGHLFAAV-NGNVIQIYSCTTFENTNNLKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWNLS 533
Cdd:cd00200 57 -------------VAASADGTYLASGsSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVE 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 534 TGKREMECVLTSCIYSSIALHSDSKIIFAVGSDQTLK--EISESSVHHEVPAFDVVYTAVAVSHSGDMVFVGTSLGTVR- 610
Cdd:cd00200 124 TGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKlwDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKl 203
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 611 -SMKYPLPLCrdfnEYQAHAGAITKMSVTNDDLFLLTASEDGSIFFWKVCSKK 662
Cdd:cd00200 204 wDLSTGKCLG----TLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGE 252
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
660-1212 |
1.46e-19 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 94.70 E-value: 1.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 660 SKKGKILKREKEFEYAEEvlimksDIEEKSRTILDLQIRVKELQIEndyqlrLKDMScyEKIKELEEtftqELESLKNKH 739
Cdd:TIGR04523 114 NDKEQKNKLEVELNKLEK------QKKENKKNIDKFLTEIKKKEKE------LEKLN--NKYNDLKK----QKEELENEL 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 740 QILQAEKDNQEmqhqlqlSELMNKHAKEMRDLESDSNQKLLmeNEKYQELqvdsqrmqeeyEKQLHNLqESKNRTVEELT 819
Cdd:TIGR04523 176 NLLEKEKLNIQ-------KNIDKIKNKLLKLELLLSNLKKK--IQKNKSL-----------ESQISEL-KKQNNQLKDNI 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 820 DYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEdREIQDIKIKyerwlIEEKESNLQ-LKGEIGVMNKR----- 893
Cdd:TIGR04523 235 EKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ-KELEQNNKK-----IKELEKQLNqLKSEISDLNNQkeqdw 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 894 LNSLQKELKERNNDIEDMKLE-QQNLQGI------IKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFV 966
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQiSQNNKIIsqlneqISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKN 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 967 LDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKM 1046
Cdd:TIGR04523 389 LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLET 468
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1047 DLHNCVGFIQDYK-KLKAGIRELYTKyVQQLEMveMEEVDTDLQQEYmrqrEYLERNLAALKKKvvkdQEVHQAAYTRIM 1125
Cdd:TIGR04523 469 QLKVLSRSINKIKqNLEQKQKELKSK-EKELKK--LNEEKKELEEKV----KDLTKKISSLKEK----IEKLESEKKEKE 537
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1126 QENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAiqdtapsNETLsspavlrLNAQKENEKIIEMQLLEIQHLRD 1205
Cdd:TIGR04523 538 SKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQT-------QKSL-------KKKQEEKQELIDQKEKEKKDLIK 603
|
....*..
gi 2024426573 1206 QVQEKGQ 1212
Cdd:TIGR04523 604 EIEEKEK 610
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
718-1071 |
3.16e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 87.82 E-value: 3.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 718 YEKIKELEEtftqELESLKNKHQILQAEKDNQEmQHQLQLSELMNKHAKEMRDLESDSNQkLLMENEKYQELQVDSQRMQ 797
Cdd:TIGR02169 673 PAELQRLRE----RLEGLKRELSSLQSELRRIE-NRLDELSQELSDASRKIGEIEKEIEQ-LEQEEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 798 EEYEKQLHNLQESKNRTVEELtDYYEEKLNEksllLEEAEEDMRQQLqAHEEIkkQIEEDEDREIQDIKIKYERWL--IE 875
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEARI-EELEEDLHK----LEEALNDLEARL-SHSRI--PEIQAELSKLEEEVSRIEARLreIE 818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 876 EKESNLQLKGEIgvmnkrlnsLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKK 955
Cdd:TIGR02169 819 QKLNRLTLEKEY---------LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK 889
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 956 KNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLK------LNITQLQQKLKATDNELhk 1029
Cdd:TIGR02169 890 ERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEeipeeeLSLEDVQAELQRVEEEI-- 967
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2024426573 1030 ERQKKQNMEAlikrfkmdlhncvgfIQDYKKLKAGIRELYTK 1071
Cdd:TIGR02169 968 RALEPVNMLA---------------IQEYEEVLKRLDELKEK 994
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
822-1162 |
2.67e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 84.72 E-value: 2.67e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 822 YEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEdedREIQ-DIKIKYERwlIEEKESNLQLkgeiGVMNKRLNSLQKE 900
Cdd:TIGR02168 170 YKERRKETERKLERTRENLDRLEDILNELERQLKS---LERQaEKAERYKE--LKAELRELEL----ALLVLRLEELREE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 901 LKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEkfkfvldHRIEQFKKQIES 980
Cdd:TIGR02168 241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE-------QQKQILRERLAN 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 981 RENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKmdlhncvgfiQDYKK 1060
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELE----------EQLET 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1061 LKAGIRELY-TKYVQQLEMVEMEEVDTDLQQeymRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLR 1139
Cdd:TIGR02168 384 LRSKVAQLElQIASLNNEIERLEARLERLED---RRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE 460
|
330 340
....*....|....*....|...
gi 2024426573 1140 QELTVAHTQVHDLQSALKLTKKK 1162
Cdd:TIGR02168 461 EALEELREELEEAEQALDAAERE 483
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
471-658 |
1.27e-15 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 80.73 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 471 SNGGHLFAAVNGNVIQIYSCTTFENTNNLKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWNLSTGKremeCVLT----SC 546
Cdd:COG2319 88 PDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGK----LLRTltghSG 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 547 IYSSIALHSDSKIIFAVGSDQTLK--EISESSVHHEVPAFDVVYTAVAVSHSGDMVFVGTSLGTVR--SMKYPLPLCRdf 622
Cdd:COG2319 164 AVTSVAFSPDGKLLASGSDDGTVRlwDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRlwDLATGKLLRT-- 241
|
170 180 190
....*....|....*....|....*....|....*.
gi 2024426573 623 neYQAHAGAITKMSVTNDDLFLLTASEDGSIFFWKV 658
Cdd:COG2319 242 --LTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDL 275
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
657-1102 |
1.10e-14 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 79.34 E-value: 1.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 657 KVCSKKGKILKREKEFEYAEEVLI-MKSDIEEKSRTILDLQIRVKELQIENDYQLRlkdmscYEKIKELEETFTQELESL 735
Cdd:PRK03918 239 EIEELEKELESLEGSKRKLEEKIReLEERIEELKKEIEELEEKVKELKELKEKAEE------YIKLSEFYEEYLDELREI 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 736 KNKHQILQAEKdnQEMQHQLQLSELMNKHAKEMRDLESDSnQKLLMENEKYQELQVDSQRMQEEYEKQlhnLQESKNRTV 815
Cdd:PRK03918 313 EKRLSRLEEEI--NGIEERIKELEEKEERLEELKKKLKEL-EKRLEELEERHELYEEAKAKKEELERL---KKRLTGLTP 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 816 EELTDYYEEKLNEKslllEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYE-----RWLIEEKESNLQLKgeigvM 890
Cdd:PRK03918 387 EKLEKELEELEKAK----EEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgRELTEEHRKELLEE-----Y 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 891 NKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNT-----NIEKRTNTIQEKEkhiydLKKKNQELEKFKF 965
Cdd:PRK03918 458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELaeqlkELEEKLKKYNLEE-----LEKKAEEYEKLKE 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 966 VLDH---RIEQFKKQIESR---ENDIKIMQKQIHEMERELEQLHKENTQLKL-NITQLQQKLKATD------NELHKERQ 1032
Cdd:PRK03918 533 KLIKlkgEIKSLKKELEKLeelKKKLAELEKKLDELEEELAELLKELEELGFeSVEELEERLKELEpfyneyLELKDAEK 612
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024426573 1033 KKQNMEALIKRFKMDLHNCVGFIQ----DYKKLKAGIRELYTKYVQQlEMVEMEEVDTDLQQEYMRQREYLERN 1102
Cdd:PRK03918 613 ELEREEKELKKLEEELDKAFEELAetekRLEELRKELEELEKKYSEE-EYEELREEYLELSRELAGLRAELEEL 685
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
720-1167 |
1.33e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 79.33 E-value: 1.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 720 KIKELEETFTQELESLKNKHQILQ-AEKDNQEMQHQLqlselmnkhaKEMRDLESDSNQKLLMENEKYQELQVDSQRMQE 798
Cdd:TIGR02168 678 EIEELEEKIEELEEKIAELEKALAeLRKELEELEEEL----------EQLRKELEELSRQISALRKDLARLEAEVEQLEE 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 799 EYEKQLHNLQESKNRTVEeltdyYEEKLNEKSLLLEEAEEDmRQQLQAheeikkqieededreiqdikikyerwlieeke 878
Cdd:TIGR02168 748 RIAQLSKELTELEAEIEE-----LEERLEEAEEELAEAEAE-IEELEA-------------------------------- 789
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 879 snlqlkgEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLkkkNQ 958
Cdd:TIGR02168 790 -------QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL---AA 859
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 959 ELEKfkfvLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNME 1038
Cdd:TIGR02168 860 EIEE----LEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1039 ALIKRfkmdlhncvgfiqdykkLKAGIRELYtkyvqqleMVEMEEVDTdLQQEYMRQREYLERNLAALKKKVVKDQEVHQ 1118
Cdd:TIGR02168 936 VRIDN-----------------LQERLSEEY--------SLTLEEAEA-LENKIEDDEEEARRRLKRLENKIKELGPVNL 989
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 2024426573 1119 AAytriMQEnvslIKEINDLRQELTvahTQVHDLQSALKltKKKQAIQD 1167
Cdd:TIGR02168 990 AA----IEE----YEELKERYDFLT---AQKEDLTEAKE--TLEEAIEE 1025
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
784-1105 |
2.50e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 78.05 E-value: 2.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 784 EKYQELqvdsqrmQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDReiq 863
Cdd:COG1196 213 ERYREL-------KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE--- 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 864 dikikyerwLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTI 943
Cdd:COG1196 283 ---------LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 944 QEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKAT 1023
Cdd:COG1196 354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1024 DNELHKERQKKQNMEALIKRFKmdlhncvgfiQDYKKLKAGIRELYTKYVQQLEmvemEEVDTDLQQEYMRQREYLERNL 1103
Cdd:COG1196 434 EEEEEEEEEALEEAAEEEAELE----------EEEEALLELLAELLEEAALLEA----ALAELLEELAEAAARLLLLLEA 499
|
..
gi 2024426573 1104 AA 1105
Cdd:COG1196 500 EA 501
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
711-1065 |
9.04e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 76.63 E-value: 9.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 711 RLKDMscyekIKELEEtftqELESLKnkhqiLQAEK-------DNQEMQHQLQLSelmnkhAKEMRDLesdsnqkllmeN 783
Cdd:TIGR02168 190 RLEDI-----LNELER----QLKSLE-----RQAEKaerykelKAELRELELALL------VLRLEEL-----------R 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 784 EKYQELQVDSQRMQEEYEK---QLHNLQE------SKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQI 854
Cdd:TIGR02168 239 EELEELQEELKEAEEELEEltaELQELEEkleelrLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 855 EEDEDREIQDikikyERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNT 934
Cdd:TIGR02168 319 EELEAQLEEL-----ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 935 NIEKRTNTIQEKEKHIYDLKKKNQELEKFKfvLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNIT 1014
Cdd:TIGR02168 394 QIASLNNEIERLEARLERLEDRRERLQQEI--EELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 2024426573 1015 QLQQKLKATDNELHKERQKKQNMEALIKRFkMDLHNCVGFIQDYKKLKAGI 1065
Cdd:TIGR02168 472 EAEQALDAAERELAQLQARLDSLERLQENL-EGFSEGVKALLKNQSGLSGI 521
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
664-1109 |
2.76e-13 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 74.72 E-value: 2.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 664 KILKREKEFE-YAEEVLIMKSDIEEKSRTILDLQIRVKELQIE-NDYQLRLKDMScyEKIKELEETfTQELESLKNKHQI 741
Cdd:PRK03918 280 EKVKELKELKeKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEiNGIEERIKELE--EKEERLEEL-KKKLKELEKRLEE 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 742 LqaEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEKQLHNLQESKNRTVEELTDY 821
Cdd:PRK03918 357 L--EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 822 YEEKLNEKSLLLEEAEED-MRQQLQAHEEIKKQIEE--DEDREIQDIKIKYERWLIEEKE--SNLQLKGEIGVMNKRLNS 896
Cdd:PRK03918 435 KGKCPVCGRELTEEHRKElLEEYTAELKRIEKELKEieEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKK 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 897 LQKE-LKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFK 975
Cdd:PRK03918 515 YNLEeLEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 976 KQIESRENDIKIMQKQIHEMERELEQLHKENTQLKlnitQLQQKLKATDNELHKERQKkqnMEALIKRFKMDLHncvgfi 1055
Cdd:PRK03918 595 KELEPFYNEYLELKDAEKELEREEKELKKLEEELD----KAFEELAETEKRLEELRKE---LEELEKKYSEEEY------ 661
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 2024426573 1056 qdykklkAGIRELYTKYVQQLEMVEME-EVDTDLQQEYMRQREYLERNLAALKKK 1109
Cdd:PRK03918 662 -------EELREEYLELSRELAGLRAElEELEKRREEIKKTLEKLKEELEEREKA 709
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
809-1045 |
5.79e-13 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 73.56 E-value: 5.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 809 ESKNRTVEELT--DYYE---EKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIkyerwlIEEKESNL-Q 882
Cdd:PRK03918 145 ESREKVVRQILglDDYEnayKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLRE------INEISSELpE 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 883 LKGEIGVMNKRLnslqKELKERNNDIEDMKLEQQNLQGIIKSLEKDISmlntNIEKRtntIQEKEKHIYDLKKKNQELEK 962
Cdd:PRK03918 219 LREELEKLEKEV----KELEELKEEIEELEKELESLEGSKRKLEEKIR----ELEER---IEELKKEIEELEEKVKELKE 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 963 FKFVLDH--RIEQFKKQIESRENDIK----IMQKQIHEMERELEQLHKENTQLKlnitQLQQKLKATDNEL------HKE 1030
Cdd:PRK03918 288 LKEKAEEyiKLSEFYEEYLDELREIEkrlsRLEEEINGIEERIKELEEKEERLE----ELKKKLKELEKRLeeleerHEL 363
|
250
....*....|....*....
gi 2024426573 1031 ----RQKKQNMEALIKRFK 1045
Cdd:PRK03918 364 yeeaKAKKEELERLKKRLT 382
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
660-1110 |
8.11e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 73.13 E-value: 8.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 660 SKKGKILKREKEFEYAEEVLIMKSDIEEKSRTildlQIRVKELQIENDYQlrlkdmscyeKIKELEETFTQ---ELESLK 736
Cdd:TIGR04523 236 KKQQEINEKTTEISNTQTQLNQLKDEQNKIKK----QLSEKQKELEQNNK----------KIKELEKQLNQlksEISDLN 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 737 N----------KHQILQAEKDNQEMQHQL--------QLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQvDSQRMQE 798
Cdd:TIGR04523 302 NqkeqdwnkelKSELKNQEKKLEEIQNQIsqnnkiisQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE-KLKKENQ 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 799 EYEKQLHNLQESKN------RTVEELTDYYEEKLN----EKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIqdiKIK 868
Cdd:TIGR04523 381 SYKQEIKNLESQINdleskiQNQEKLNQQKDEQIKklqqEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEL---IIK 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 869 YERWLIEEKESNLQ-LKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISM---------------- 931
Cdd:TIGR04523 458 NLDNTRESLETQLKvLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSlkekieklesekkeke 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 932 ----------------------------LNTNIEKRTNTIQEkekhiydLKKKNQELEKfkfvldhRIEQFKKQIESREN 983
Cdd:TIGR04523 538 skisdledelnkddfelkkenlekeideKNKEIEELKQTQKS-------LKKKQEEKQE-------LIDQKEKEKKDLIK 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 984 DIKIMQKQIHEMERELEQLHKENTQLKLNITQLQ-------QKLKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQ 1056
Cdd:TIGR04523 604 EIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKskknklkQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMK 683
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024426573 1057 DYKK-LKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQREY---LERNLAALKKKV 1110
Cdd:TIGR04523 684 DWLKeLSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDEFskeLENIIKNFNKKF 741
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
673-1207 |
8.83e-13 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 73.23 E-value: 8.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 673 EYAEEV------LIMKSDIEEKSR-----TILDLQIRVKELQIEND--YQLRLKDMSCYEKIKELEETFTQELESLKN-K 738
Cdd:pfam15921 82 EYSHQVkdlqrrLNESNELHEKQKfylrqSVIDLQTKLQEMQMERDamADIRRRESQSQEDLRNQLQNTVHELEAAKClK 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 739 HQILqaEKDNQEMQhqlQLSELMNKHA---KEMR----DLESDSNQKLL----MENEKYQELQVDSQRMQEEYEKQLHNL 807
Cdd:pfam15921 162 EDML--EDSNTQIE---QLRKMMLSHEgvlQEIRsilvDFEEASGKKIYehdsMSTMHFRSLGSAISKILRELDTEISYL 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 808 QESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHE-EIKKQIEEDEDREIQDIKIKYERWLIEE--KESNLQLK 884
Cdd:pfam15921 237 KGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEvEITGLTEKASSARSQANSIQSQLEIIQEqaRNQNSMYM 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 885 GEIGVMNKRLNSLQKELKERNNDIEDMkleqqnlqgiIKSLEKDISMLNTNI-EKRT----------NTIQEKEKHIYDL 953
Cdd:pfam15921 317 RQLSDLESTVSQLRSELREAKRMYEDK----------IEELEKQLVLANSELtEARTerdqfsqesgNLDDQLQKLLADL 386
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 954 KKKNQEL----EKFKFVLDH------RIEQFKKQIESR-------ENDIKIMQKQIH-EMERELEQLHKENTQLKlNITQ 1015
Cdd:pfam15921 387 HKREKELslekEQNKRLWDRdtgnsiTIDHLRRELDDRnmevqrlEALLKAMKSECQgQMERQMAAIQGKNESLE-KVSS 465
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1016 LQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQDYKK----LKAGIRELYTKYVQQLEMVEMEEVDTDLQQE 1091
Cdd:pfam15921 466 LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERaieaTNAEITKLRSRVDLKLQELQHLKNEGDHLRN 545
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1092 YMRQREYLERNLAAlKKKVVK---------DQEVHQAAYT--RIMQENVSLIKEINDLRQELtvahtqvhdlqSALKLTK 1160
Cdd:pfam15921 546 VQTECEALKLQMAE-KDKVIEilrqqienmTQLVGQHGRTagAMQVEKAQLEKEINDRRLEL-----------QEFKILK 613
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 2024426573 1161 KKQ--AIQDTAPSNETLSSPAVLRLNAQKENEKIIEmqllEIQHLRDQV 1207
Cdd:pfam15921 614 DKKdaKIRELEARVSDLELEKVKLVNAGSERLRAVK----DIKQERDQL 658
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
664-1167 |
1.10e-12 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 72.45 E-value: 1.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 664 KILKREKEFEYAEEVLI-MKSDIEEKSRTILDLQIRVKELQIENDYQLRLKdmscYEKIKELEETFTQELEslknkhqil 742
Cdd:pfam05483 170 KTKKYEYEREETRQVYMdLNNNIEKMILAFEELRVQAENARLEMHFKLKED----HEKIQHLEEEYKKEIN--------- 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 743 qaEKDNQEMQHQLQLSELMNKhakeMRDLesdsnqKLLMENEKYQELQVDSQ-RMQEEYEKQLHNLQESKNRTVEELTDY 821
Cdd:pfam05483 237 --DKEKQVSLLLIQITEKENK----MKDL------TFLLEESRDKANQLEEKtKLQDENLKELIEKKDHLTKELEDIKMS 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 822 YEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEededrEIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKEL 901
Cdd:pfam05483 305 LQRSMSTQKALEEDLQIATKTICQLTEEKEAQME-----ELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQL 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 902 KERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEK---EKHIYDLKKKNQELEKFKFVLDHRIEQFKKQI 978
Cdd:pfam05483 380 KIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKkqfEKIAEELKGKEQELIFLLQAREKEIHDLEIQL 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 979 ESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKatdnelhKERQKKQNMEALIKRFKMDLHNCvgfiqdy 1058
Cdd:pfam05483 460 TAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENK-------ELTQEASDMTLELKKHQEDIINC------- 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1059 kklkagiRELYTKYVQQLEmvEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVS---LIKEI 1135
Cdd:pfam05483 526 -------KKQEERMLKQIE--NLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQmkiLENKC 596
|
490 500 510
....*....|....*....|....*....|..
gi 2024426573 1136 NDLRQELTVAHTQVHDLQSALKLTKKKQAIQD 1167
Cdd:pfam05483 597 NNLKKQIENKNKNIEELHQENKALKKKGSAEN 628
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
658-1005 |
1.28e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.79 E-value: 1.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 658 VCSKKGKILKR-EKEFEYAEEVLIMKSDIEEKSRTILDLQIRVKELQIEN-DYQLrlkdmscyekikeleETFTQELESL 735
Cdd:TIGR02169 192 IIDEKRQQLERlRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAiERQL---------------ASLEEELEKL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 736 KNkhqilQAEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQKLLMENEKYQELqvdSQRMQEEYEKQLHNLQESKNRTV 815
Cdd:TIGR02169 257 TE-----EISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIAS---LERSIAEKERELEDAEERLAKLE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 816 EELTDYYEEKLNEKSLLLEEAEEdmRQQLQAHEEIKKQIEEDEDREIQDIKIKYERW---LIEEKESNLQLKGEIGVMNK 892
Cdd:TIGR02169 329 AEIDKLLAEIEELEREIEEERKR--RDKLTEEYAELKEELEDLRAELEEVDKEFAETrdeLKDYREKLEKLKREINELKR 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 893 RLNSLQKELKERNNDIEDMKLEqqnlqgiIKSLEKDISMLNTniekrtntiqEKEKHIYDLKKKNQELEKFKFVLdhriE 972
Cdd:TIGR02169 407 ELDRLQEELQRLSEELADLNAA-------IAGIEAKINELEE----------EKEDKALEIKKQEWKLEQLAADL----S 465
|
330 340 350
....*....|....*....|....*....|...
gi 2024426573 973 QFKKQIESRENDIKIMQKQIHEMERELEQLHKE 1005
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
664-1216 |
1.60e-12 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 72.31 E-value: 1.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 664 KILKREKEFEYAEEvlimKSDIEEKSRTILDLQIRVKELQIENDYQLRLkdmscYEKIKELEETFTQELESLKNKHQILQ 743
Cdd:pfam02463 168 KRKKKEALKKLIEE----TENLAELIIDLEELKLQELKLKEQAKKALEY-----YQLKEKLELEEEYLLYLDYLKLNEER 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 744 AEKDNQEMQHQLQLSELMNKhakemrdlesdsnqkllmENEKYQELQVDSQRMQEEYEKQLHNLQESKNRTVEEltdyyE 823
Cdd:pfam02463 239 IDLLQELLRDEQEEIESSKQ------------------EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE-----E 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 824 EKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIkikyERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKE 903
Cdd:pfam02463 296 EELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEI----EELEKELKELEIKREAEEEEEEELEKLQEKLEQL 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 904 RNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIE--QFKKQIESR 981
Cdd:pfam02463 372 EEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIElkQGKLTEEKE 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 982 ENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNE--LHKERQKKQNMEALIKRFKMDLHNCVGFIQDYK 1059
Cdd:pfam02463 452 ELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEerSQKESKARSGLKVLLALIKDGVGGRIISAHGRL 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1060 KLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLR 1139
Cdd:pfam02463 532 GDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKA 611
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 1140 QELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSS--PAVLRLNAQKENEKIIEMQLLEIQHLRDQVQEKGQGLEA 1216
Cdd:pfam02463 612 TLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRkgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELA 690
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
721-1044 |
1.67e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.28 E-value: 1.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 721 IKELEetftQELESLKN------KHQILQAEKDnqEMQHQLQLSELMNKHAKEmrdlesdsnQKLLMENEKYQELQVDSQ 794
Cdd:COG1196 195 LGELE----RQLEPLERqaekaeRYRELKEELK--ELEAELLLLKLRELEAEL---------EELEAELEELEAELEELE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 795 RMQEEYEKQLHNLQESKNRTVEELtdyyeEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERwLI 874
Cdd:COG1196 260 AELAELEAELEELRLELEELELEL-----EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE-LE 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 875 EEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLK 954
Cdd:COG1196 334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 955 KKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKK 1034
Cdd:COG1196 414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
|
330
....*....|
gi 2024426573 1035 QNMEALIKRF 1044
Cdd:COG1196 494 LLLLEAEADY 503
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
731-1232 |
2.42e-12 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 71.31 E-value: 2.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 731 ELESLKNKHQILQAEKDNQEMQHQLQLSELMNKHAKEMRDLEsdsnqkllMENEKYQELQVDSQRMQEEYEKQLHNLQES 810
Cdd:pfam05557 3 ELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLD--------RESDRNQELQKRIRLLEKREAEAEEALREQ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 811 --KNRTVEELTDYYEEKLNEKSLLLEEAEEdmrqqlqAHEEIKKQIEEdedreiqdikikyERWLIEEKESNLQlkgeig 888
Cdd:pfam05557 75 aeLNRLKKKYLEALNKKLNEKESQLADARE-------VISCLKNELSE-------------LRRQIQRAELELQ------ 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 889 vmnkRLNSLQKELKERNndiedmKLEQQNLQGIikslekdiSMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLd 968
Cdd:pfam05557 129 ----STNSELEELQERL------DLLKAKASEA--------EQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSEIV- 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 969 hrieqfkKQIESRendikimQKQIHEMERELEQLHKENTQL---KLNITQLQQKLKATDNELHKE---RQKKQNMEALIK 1042
Cdd:pfam05557 190 -------KNSKSE-------LARIPELEKELERLREHNKHLnenIENKLLLKEEVEDLKRKLEREekyREEAATLELEKE 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1043 RFKMDLHNCVGFIQDY-------KKLKAGIRELytkyvQQLEMVEMEEV---DTDLQQEYMRQREyLERNLAALKKKVVK 1112
Cdd:pfam05557 256 KLEQELQSWVKLAQDTglnlrspEDLSRRIEQL-----QQREIVLKEENsslTSSARQLEKARRE-LEQELAQYLKKIED 329
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1113 DQEV--HQAAYTRIMQENVSLI-KEINDLRQ-------ELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSSPAVLR 1182
Cdd:pfam05557 330 LNKKlkRHKALVRRLQRRVLLLtKERDGYRAilesydkELTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEE 409
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 1183 LNAQKENEKIIEMqllEIQHLRDQVQEKGQGLEAQPL--LYGMLPKLNLERS 1232
Cdd:pfam05557 410 LGGYKQQAQTLER---ELQALRQQESLADPSYSKEEVdsLRRKLETLELERQ 458
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
892-1193 |
6.97e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 70.35 E-value: 6.97e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 892 KRLNSLQKELKERN-----NDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFV 966
Cdd:COG1196 213 ERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 967 LDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKM 1046
Cdd:COG1196 293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1047 DLHNCVGfiQDYKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQA------A 1120
Cdd:COG1196 373 ELAEAEE--ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAleeaaeE 450
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 1121 YTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSSPAVLRLNAQKENEKII 1193
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
719-1157 |
8.30e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 69.71 E-value: 8.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEETFT---------------------------QELESLKN-----KHQILQAEKDNQEMQHQL-QLSELMNKHA 765
Cdd:PRK03918 193 ELIKEKEKELEevlreineisselpelreeleklekevKELEELKEeieelEKELESLEGSKRKLEEKIrELEERIEELK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 766 KEMRDLEsdSNQKLLMENEKYQELQVDSQRMQEEYEKQLHNLQ--------------------ESKNRTVEELTDYYEEK 825
Cdd:PRK03918 273 KEIEELE--EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEkrlsrleeeingieerikelEEKEERLEELKKKLKEL 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 826 LNEKSLLLEEAE--EDMRQQLQAHEEIKKQIeedEDREIQDIKIKYErwliEEKESNLQLKGEIGVMNKRLNSLQKELKE 903
Cdd:PRK03918 351 EKRLEELEERHElyEEAKAKKEELERLKKRL---TGLTPEKLEKELE----ELEKAKEEIEEEISKITARIGELKKEIKE 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 904 RNNDIEDMK------------LEQQNLQGIIKSLEKDISmlntNIEKRTNTIQEKEKhiyDLKKKNQELEKF-----KFV 966
Cdd:PRK03918 424 LKKAIEELKkakgkcpvcgreLTEEHRKELLEEYTAELK----RIEKELKEIEEKER---KLRKELRELEKVlkkesELI 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 967 LDHRIEQFKKQIESRENDIKImqKQIHEMERELEQLHKENTQLKLNITQLQ---QKLKATDNELHKERQKKQNMEALIKR 1043
Cdd:PRK03918 497 KLKELAEQLKELEEKLKKYNL--EELEKKAEEYEKLKEKLIKLKGEIKSLKkelEKLEELKKKLAELEKKLDELEEELAE 574
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1044 FKMDLHNcVGFiQDYKKLKAGIREL---YTKYVQQL----EMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEV 1116
Cdd:PRK03918 575 LLKELEE-LGF-ESVEELEERLKELepfYNEYLELKdaekELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEL 652
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 2024426573 1117 HQA----AYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALK 1157
Cdd:PRK03918 653 EKKyseeEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLE 697
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
661-1212 |
1.20e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.32 E-value: 1.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 661 KKGKILKREKEF-EYAEEVLIMKSDIEEKSRTI---------LDLQIRVKELQIENDYQLRLKDMSCYEKIKELEETFTQ 730
Cdd:TIGR02168 272 LRLEVSELEEEIeELQKELYALANEISRLEQQKqilrerlanLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 731 ELESLKNKHQILQAEKDNQEMQHQL---QLSELMNKHAKEMRDLESDSNQKLLMENEKyQELQVDSQRMQEEYEKQLHNL 807
Cdd:TIGR02168 352 ELESLEAELEELEAELEELESRLEEleeQLETLRSKVAQLELQIASLNNEIERLEARL-ERLEDRRERLQQEIEELLKKL 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 808 QESKNRTVE---ELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDR---------EIQDIKIKYERWLIE 875
Cdd:TIGR02168 431 EEAELKELQaelEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQlqarldsleRLQENLEGFSEGVKA 510
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 876 EKESNLQLKGEIGVMNKRLN---------------SLQKELKERNNDIED------------------------------ 910
Cdd:TIGR02168 511 LLKNQSGLSGILGVLSELISvdegyeaaieaalggRLQAVVVENLNAAKKaiaflkqnelgrvtflpldsikgteiqgnd 590
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 911 --MKLEQQNLQGIIKSLEK------------------------------------------------------------- 927
Cdd:TIGR02168 591 reILKNIEGFLGVAKDLVKfdpklrkalsyllggvlvvddldnalelakklrpgyrivtldgdlvrpggvitggsaktns 670
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 928 -------DISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELE 1000
Cdd:TIGR02168 671 silerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1001 QLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNcvgFIQDYKKLKAGIRELYTKYVQQLEMVE 1080
Cdd:TIGR02168 751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA---LREALDELRAELTLLNEEAANLRERLE 827
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1081 MEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALK--L 1158
Cdd:TIGR02168 828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRelE 907
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2024426573 1159 TKKKQAIQDTAPSNETLSSpAVLRLNAQKenekiiemqlLEIQHLRDQVQEKGQ 1212
Cdd:TIGR02168 908 SKRSELRRELEELREKLAQ-LELRLEGLE----------VRIDNLQERLSEEYS 950
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
686-1210 |
1.34e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 69.38 E-value: 1.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 686 EEKSRTILDLQIRVKELQIENDYQLRL--KDMSCYEKIKELEETFTQELESLKNKHQILQAEKDNQEMQHQLQLSELMNK 763
Cdd:pfam15921 377 DQLQKLLADLHKREKELSLEKEQNKRLwdRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGK 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 764 HakemRDLESDSNQKLLMENEKYQelqvdSQRMQEEYEKQLHNLqESKNRTVEELTDYYEEKlnEKSLLLEEAE-EDMRQ 842
Cdd:pfam15921 457 N----ESLEKVSSLTAQLESTKEM-----LRKVVEELTAKKMTL-ESSERTVSDLTASLQEK--ERAIEATNAEiTKLRS 524
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 843 ----QLQAHEEIKKqiEEDEDREIQDI----------KIKYERWLIEEKESNLQLKGE----IGVMNKRLNSLQKELKER 904
Cdd:pfam15921 525 rvdlKLQELQHLKN--EGDHLRNVQTEcealklqmaeKDKVIEILRQQIENMTQLVGQhgrtAGAMQVEKAQLEKEINDR 602
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 905 NNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEkfkfvldHRIEQFKKQIESREND 984
Cdd:pfam15921 603 RLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLL-------NEVKTSRNELNSLSED 675
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 985 IKIMQKQIHEMERELEqlhkentqlkLNITQLQQKLKATDNELHKERQKKQNMEA----------------LIKRFKMD- 1047
Cdd:pfam15921 676 YEVLKRNFRNKSEEME----------TTTNKLKMQLKSAQSELEQTRNTLKSMEGsdghamkvamgmqkqiTAKRGQIDa 745
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1048 LHNCVGFIQD----YKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQRE-YLERNLA----ALKKKVVKDQEVhQ 1118
Cdd:pfam15921 746 LQSKIQFLEEamtnANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQErRLKEKVAnmevALDKASLQFAEC-Q 824
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1119 AAYTRIMQENVSL-IKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLS---SPAVLRLNAQKENEKIIE 1194
Cdd:pfam15921 825 DIIQRQEQESVRLkLQHTLDVKELQGPGYTSNSSMKPRLLQPASFTRTHSNVPSSQSTAsflSHHSRKTNALKEDPTRDL 904
|
570
....*....|....*.
gi 2024426573 1195 MQLLeiQHLRDQVQEK 1210
Cdd:pfam15921 905 KQLL--QELRSVINEE 918
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
33-534 |
1.90e-11 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 67.63 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 33 AAGAACAQFHTEQRWHKFIPGREKSRGVRALAVSRSRRYLAVSEMAEEEPALTVYELTAEPPRRRRTLSAAELPARetvA 112
Cdd:COG2319 7 AALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVL---S 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 113 LAFSPDGRYLAAATGPPEAQLalwlWEKQRLLAVVRLEAADIGVCQVSFSPqDNAQVcVTGNgffklfkySEGTLKqinl 192
Cdd:COG2319 84 VAFSPDGRLLASASADGTVRL----WDLATGLLLRTLTGHTGAVRSVAFSP-DGKTL-ASGS--------ADGTVR---- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 193 qkgepqnylchawlseeeiicgtatgklflfesgelLWqrDVEYRKPPKELEEGTRAkdyvsssdvsgeptsedsgslqd 272
Cdd:COG2319 146 ------------------------------------LW--DLATGKLLRTLTGHSGA----------------------- 164
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 273 slpqISAVAaYS---KGFACSSSPGVVLLFEKTNKEVYKEsqeiwlprdlfttvpkLSGRQD-ITCICFSPSEEVLVVST 348
Cdd:COG2319 165 ----VTSVA-FSpdgKLLASGSDDGTVRLWDLATGKLLRT----------------LTGHTGaVRSVAFSPDGKLLASGS 223
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 349 TKNQLYMFTMPSADYLKEesshfeylhFPLHSASITGLDVCIRRPIVATCSLDKSVRVWNYKTNT-LELCKEFWEEAYTV 427
Cdd:COG2319 224 ADGTVRLWDLATGKLLRT---------LTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGElLRTLTGHSGGVNSV 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 428 ALHPTGLFCLVGFSDK-LRFISL-LYEDMHVFKDfPVRECRECSFS-NGGHLFAAVNGNVIQIYSCTTFENTNNLKGHSG 504
Cdd:COG2319 295 AFSPDGKLLASGSDDGtVRLWDLaTGKLLRTLTG-HTGAVRSVAFSpDGKTLASGSDDGTVRLWDLATGELLRTLTGHTG 373
|
490 500 510
....*....|....*....|....*....|
gi 2024426573 505 KIHAVKWSADDSKCFSCDTHGAVYEWNLST 534
Cdd:COG2319 374 AVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
718-1048 |
4.17e-11 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 67.17 E-value: 4.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 718 YEKIKELEE--------TFTQELESLKNKHQILQAEKDNQEMQHQLQlsELMNKHakeMRDLESDSNQkLLMENEKYQEL 789
Cdd:PRK04778 28 YKRIDELEErkqelenlPVNDELEKVKKLNLTGQSEEKFEEWRQKWD--EIVTNS---LPDIEEQLFE-AEELNDKFRFR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 790 QV-----DSQRMQEEYEKQLHNL---------QESKNRT-VEELTDYYEE---KLNEKSLLLEEAEEDMRQQLQAHEEIK 851
Cdd:PRK04778 102 KAkheinEIESLLDLIEEDIEQIleelqelleSEEKNREeVEQLKDLYRElrkSLLANRFSFGPALDELEKQLENLEEEF 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 852 KQIEE-------DEDREIqdikikyerwLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIE----DMK-----LEQ 915
Cdd:PRK04778 182 SQFVEltesgdyVEAREI----------LDQLEEELAALEQIMEEIPELLKELQTELPDQLQELKagyrELVeegyhLDH 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 916 QNLQGIIKSLEKDISMLNTNIEkrtntiqekEKHIYDLKKKNQELEKfkfVLDHRIEQFKKQIESRendiKIMQKQIHEM 995
Cdd:PRK04778 252 LDIEKEIQDLKEQIDENLALLE---------ELDLDEAEEKNEEIQE---RIDQLYDILEREVKAR----KYVEKNSDTL 315
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 996 ERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDL 1048
Cdd:PRK04778 316 PDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQLEKQLESLEKQYDEIT 368
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
690-1156 |
5.73e-11 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 66.80 E-value: 5.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 690 RTILDLQIRVKEL-QIENDYQL-RLKDMSCYEKIKELEETFTQELESLKNKH------QILQAEKDNQEMqHQLQLSELM 761
Cdd:pfam06160 10 KEIDELEERKNELmNLPVQEELsKVKKLNLTGETQEKFEEWRKKWDDIVTKSlpdieeLLFEAEELNDKY-RFKKAKKAL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 762 NKHAKEMRDLESDSNQKL-----LMENEKYQELQVDSQRmqEEYEKqLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEA 836
Cdd:pfam06160 89 DEIEELLDDIEEDIKQILeeldeLLESEEKNREEVEELK--DKYRE-LRKTLLANRFSYGPAIDELEKQLAEIEEEFSQF 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 837 EEDMRQQ--LQAHEEIKKQIEE--DEDREIQDIKIKYERwlieekesnlqLKGEIGVMNKRLNSLQKELKERNNDIEDMK 912
Cdd:pfam06160 166 EELTESGdyLEAREVLEKLEEEtdALEELMEDIPPLYEE-----------LKTELPDQLEELKEGYREMEEEGYALEHLN 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 913 LEQQnLQGIIKSLEKDISMLNT----NIEKRTNTIQEKEKHIYDLKKKnqELEKFKFVldhrieqfkkqiesrendikim 988
Cdd:pfam06160 235 VDKE-IQQLEEQLEENLALLENleldEAEEALEEIEERIDQLYDLLEK--EVDAKKYV---------------------- 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 989 QKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNcvgfIQDYKKLKAGIREL 1068
Cdd:pfam06160 290 EKNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGLEKQLEELEKRYDEIVER----LEEKEVAYSELQEE 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1069 YTKYVQQLEMVE--MEEVDTDLQQeyMRQREylernLAALKKKVVKDQEVHqAAYTRIMQENVSLIKEinDLRQELTVAH 1146
Cdd:pfam06160 366 LEEILEQLEEIEeeQEEFKESLQS--LRKDE-----LEAREKLDEFKLELR-EIKRLVEKSNLPGLPE--SYLDYFFDVS 435
|
490
....*....|
gi 2024426573 1147 TQVHDLQSAL 1156
Cdd:pfam06160 436 DEIEDLADEL 445
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
671-1169 |
5.95e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 67.05 E-value: 5.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 671 EFEYAEEV----------LIMKSDIEEKSR--TILDLQIRVKELQIENDYQLRLKDMscyEKIKELEETFTQELESLKNK 738
Cdd:pfam05483 228 EEEYKKEIndkekqvsllLIQITEKENKMKdlTFLLEESRDKANQLEEKTKLQDENL---KELIEKKDHLTKELEDIKMS 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 739 HQilQAEKDNQEMQHQLQLS-----ELMNKHAKEMRDLESDSNQKLLMENE------KYQELQVDSQRMQEEYEKQLHNL 807
Cdd:pfam05483 305 LQ--RSMSTQKALEEDLQIAtkticQLTEEKEAQMEELNKAKAAHSFVVTEfeattcSLEELLRTEQQRLEKNEDQLKII 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 808 Q---ESKNRTVEELTDYYEEK----------LNEKSLLLEEAE--EDMRQQLQAHEEIKKQIEEDEDREIQDIKIKY--- 869
Cdd:pfam05483 383 TmelQKKSSELEEMTKFKNNKeveleelkkiLAEDEKLLDEKKqfEKIAEELKGKEQELIFLLQAREKEIHDLEIQLtai 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 870 ----ERWLIEEKESNLQLKGEiGVMNKRL----NSLQKELKERNNDIEDMKLEQQNLQGII----KSLEKDISMLNTNIE 937
Cdd:pfam05483 463 ktseEHYLKEVEDLKTELEKE-KLKNIELtahcDKLLLENKELTQEASDMTLELKKHQEDIinckKQEERMLKQIENLEE 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 938 KRTNTIQEKEKHIYDLKKKNQEL-------EKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLK 1010
Cdd:pfam05483 542 KEMNLRDELESVREEFIQKGDEVkckldksEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK 621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1011 LNITQLQQKLKATD---NELHKE-RQKKQNMEALIKRFKMDLHncVGFIQDYKKLKagirELYTKYVQQLEMVEME-EVD 1085
Cdd:pfam05483 622 KKGSAENKQLNAYEikvNKLELElASAKQKFEEIIDNYQKEIE--DKKISEEKLLE----EVEKAKAIADEAVKLQkEID 695
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1086 TDLQQEYMRQREYLERNLAALkKKVVKDQEVHQAAYTRIMQEN----VSLIKEINDLRQELTVAHTQVhDLQSALKLTKK 1161
Cdd:pfam05483 696 KRCQHKIAEMVALMEKHKHQY-DKIIEERDSELGLYKNKEQEQssakAALEIELSNIKAELLSLKKQL-EIEKEEKEKLK 773
|
....*...
gi 2024426573 1162 KQAIQDTA 1169
Cdd:pfam05483 774 MEAKENTA 781
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
782-1137 |
6.76e-11 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 67.12 E-value: 6.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 782 ENEKYQELQVDSQRMQEEYEKQLHNLQESKNRtveeltdyYEEKLNEKSLLLEEAEEdMRQQLQAheeiKKQieededrE 861
Cdd:pfam01576 13 ELQKVKERQQKAESELKELEKKHQQLCEEKNA--------LQEQLQAETELCAEAEE-MRARLAA----RKQ-------E 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 862 IQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISML---NTNIEK 938
Cdd:pfam01576 73 LEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLedqNSKLSK 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 939 RTNTIQEK----EKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNIT 1014
Cdd:pfam01576 153 ERKLLEERisefTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1015 QLQQKLKATDNELHK-----ERQKKQNMEALIKRFKMDLHncVGFIQDYKKLKAGIRELYTKYVQQLEMvEMEEVDTDL- 1088
Cdd:pfam01576 233 ELRAQLAKKEEELQAalarlEEETAQKNNALKKIRELEAQ--ISELQEDLESERAARNKAEKQRRDLGE-ELEALKTELe 309
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024426573 1089 --------QQEYMRQReylERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEIND 1137
Cdd:pfam01576 310 dtldttaaQQELRSKR---EQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTE 363
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
719-1206 |
8.15e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 66.67 E-value: 8.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEETFTQELESLKNKhqiLQAEKDNQEMQHQlQLSELMNKHAKEMRDLESD--SNQKLLMENEKYQELqvdsqrm 796
Cdd:pfam05483 88 EKIKKWKVSIEAELKQKENK---LQENRKIIEAQRK-AIQELQFENEKVSLKLEEEiqENKDLIKENNATRHL------- 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 797 qeeyekqLHNLQESKNRTVEElTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEE 876
Cdd:pfam05483 157 -------CNLLKETCARSAEK-TKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 877 KEsnlqLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKrtntIQEKEKHIydlkkk 956
Cdd:pfam05483 229 EE----YKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKE----LIEKKDHL------ 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 957 NQELEKFKFVLDHRIEQFKkqieSRENDIKIMQKQIH----EMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQ 1032
Cdd:pfam05483 295 TKELEDIKMSLQRSMSTQK----ALEEDLQIATKTICqlteEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1033 KKQNMEALIKRFKMDLHNcvgfiqdykklKAGIRELYTKYVQQLEmVEMEEVDTDL--QQEYMRQREYLERNLAALKKkv 1110
Cdd:pfam05483 371 RLEKNEDQLKIITMELQK-----------KSSELEEMTKFKNNKE-VELEELKKILaeDEKLLDEKKQFEKIAEELKG-- 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1111 vKDQEVHQAAYTRimqenvslIKEINDLRQELTVAHT-------QVHDLQSALKLTKKKQaIQDTAPSNETL-------- 1175
Cdd:pfam05483 437 -KEQELIFLLQAR--------EKEIHDLEIQLTAIKTseehylkEVEDLKTELEKEKLKN-IELTAHCDKLLlenkeltq 506
|
490 500 510
....*....|....*....|....*....|....*.
gi 2024426573 1176 -SSPAVLRLNAQKE----NEKIIEMQLLEIQHLRDQ 1206
Cdd:pfam05483 507 eASDMTLELKKHQEdiinCKKQEERMLKQIENLEEK 542
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
673-977 |
9.22e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 66.63 E-value: 9.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 673 EYAEEVLIMKSDIEEKSRTILDLQIRVKELQIE-NDYQLRLKD--------MSCYEKIKELEETFTQELESLKNKHQILQ 743
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRlDELSQELSDasrkigeiEKEIEQLEQEEEKLKERLEELEEDLSSLE 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 744 AEKDN--QEMQH--------QLQLSEL----------------------MNKHAKEMRDLES---DSNQKLlmeNEKYQE 788
Cdd:TIGR02169 751 QEIENvkSELKElearieelEEDLHKLeealndlearlshsripeiqaeLSKLEEEVSRIEArlrEIEQKL---NRLTLE 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 789 LQVDSQRMQEEYEKQ--LHNLQESKNRTVEELTDYYEEKLNEksllLEEAEEDMRQQLQAHEEIKKQIEEDEdREIQDIK 866
Cdd:TIGR02169 828 KEYLEKEIQELQEQRidLKEQIKSIEKEIENLNGKKEELEEE----LEELEAALRDLESRLGDLKKERDELE-AQLRELE 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 867 IKYE--RWLIEEKESNL-QLKGEIGVMNKRLNSLQKELKE------RNNDIEDMKLEQQNLQGIIKSLEkDISMLntnie 937
Cdd:TIGR02169 903 RKIEelEAQIEKKRKRLsELKAKLEALEEELSEIEDPKGEdeeipeEELSLEDVQAELQRVEEEIRALE-PVNML----- 976
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 2024426573 938 krtnTIQEKE---KHIYDLKKKNQELEKFKFVLDHRIEQFKKQ 977
Cdd:TIGR02169 977 ----AIQEYEevlKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
112-448 |
9.57e-11 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 64.28 E-value: 9.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 112 ALAFSPDGRYLAAATGppEAQLALWLWEKQRLLAvvRLEAADIGVCQVSFSPQDNAQVCVTGNGFFKLFKYSegTLKQIN 191
Cdd:cd00200 14 CVAFSPDGKLLATGSG--DGTIKVWDLETGELLR--TLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLE--TGECVR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 192 LQKGEPQNYLCHAWLSEEEIICGTAT-GKLFLFesgellwqrDVEYRKPPKELEEgtrAKDYVSSSDVSGeptsedsgsl 270
Cdd:cd00200 88 TLTGHTSYVSSVAFSPDGRILSSSSRdKTIKVW---------DVETGKCLTTLRG---HTDWVNSVAFSP---------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 271 qdslpqisavaaySKGFACSSSpgvvllfekTNKEVYkesqeIWlprDL--FTTVPKLSGRQD-ITCICFSPSEEVLVVS 347
Cdd:cd00200 146 -------------DGTFVASSS---------QDGTIK-----LW---DLrtGKCVATLTGHTGeVNSVAFSPDGEKLLSS 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 348 TTKNQLYMFTMPSADYLKEesshfeylhFPLHSASITGLDVCIRRPIVATCSLDKSVRVWNYKTntlelckefWEEAYTV 427
Cdd:cd00200 196 SSDGTIKLWDLSTGKCLGT---------LRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRT---------GECVQTL 257
|
330 340
....*....|....*....|.
gi 2024426573 428 ALHPTGLFCLVGFSDKLRFIS 448
Cdd:cd00200 258 SGHTNSVTSLAWSPDGKRLAS 278
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
662-1132 |
1.55e-10 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 65.76 E-value: 1.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 662 KGKILKREKEFEYAEEVLIMKSDIEEKSRTILDLQIRVKELQIENDYQLRLKDMSCYE--------KIKELEETFTQELE 733
Cdd:TIGR00618 317 QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQhtltqhihTLQQQKTTLTQKLQ 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 734 SLKNKHQILQAEKDNQEMQHQLQLSE---LMNKHAKEMRDLESDSNQKLLMENE---------------------KYQEL 789
Cdd:TIGR00618 397 SLCKELDILQREQATIDTRTSAFRDLqgqLAHAKKQQELQQRYAELCAAAITCTaqceklekihlqesaqslkerEQQLQ 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 790 QVDSQRMQEEYEKQLH----NLQESKNRTVEELTDYYEEKLNEKSLL----------------LEEAEEDMRQQLQAHEE 849
Cdd:TIGR00618 477 TKEQIHLQETRKKAVVlarlLELQEEPCPLCGSCIHPNPARQDIDNPgpltrrmqrgeqtyaqLETSEEDVYHQLTSERK 556
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 850 IKKQIEEDEDREIQDIKIKYERW--LIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSL-- 925
Cdd:TIGR00618 557 QRASLKEQMQEIQQSFSILTQCDnrSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLqq 636
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 926 -EKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLD--HRIEQFKKQIESRENDIKIMQKQIHEMERELEQL 1002
Cdd:TIGR00618 637 cSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLalQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEY 716
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1003 HKENTQLKLNITQLQQKLKAtDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMVEME 1082
Cdd:TIGR00618 717 DREFNEIENASSSLGSDLAA-REDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLRE 795
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1083 EVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLI 1132
Cdd:TIGR00618 796 EDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLG 845
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
654-1027 |
2.01e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 65.47 E-value: 2.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 654 FFWKVCSKKGKILKREKEFEYAEEVLIMK-SDIEEKSRTILDLQIRVKELqiENDYQLRLKDMSCYEKIKELEEtftqEL 732
Cdd:PRK03918 301 FYEEYLDELREIEKRLSRLEEEINGIEERiKELEEKEERLEELKKKLKEL--EKRLEELEERHELYEEAKAKKE----EL 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 733 ESLKNKHQILQAEKDNQEMQH----QLQLSELMNKHAKEMRDLESDSNQ--KLLMENEKYQ--------EL-QVDSQRMQ 797
Cdd:PRK03918 375 ERLKKRLTGLTPEKLEKELEElekaKEEIEEEISKITARIGELKKEIKElkKAIEELKKAKgkcpvcgrELtEEHRKELL 454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 798 EEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAE-----------EDMRQQLQAH--EEIKKQIEEDEDREIQD 864
Cdd:PRK03918 455 EEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEliklkelaeqlKELEEKLKKYnlEELEKKAEEYEKLKEKL 534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 865 IKIKYE-RWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNN--------DIEDMKLEQQNLQGI-------------- 921
Cdd:PRK03918 535 IKLKGEiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKeleelgfeSVEELEERLKELEPFyneylelkdaekel 614
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 922 ------IKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKK------------KNQELEKFKFVLDHRIEQFKKQIESREN 983
Cdd:PRK03918 615 ereekeLKKLEEELDKAFEELAETEKRLEELRKELEELEKkyseeeyeelreEYLELSRELAGLRAELEELEKRREEIKK 694
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2024426573 984 DIKIMQKQIHEMERELEQLHKENTQLKlNITQLQQKLKATDNEL 1027
Cdd:PRK03918 695 TLEKLKEELEEREKAKKELEKLEKALE-RVEELREKVKKYKALL 737
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
633-1079 |
2.75e-10 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 64.59 E-value: 2.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 633 TKMSVTNDDLFLLTASEDGSI---FFWKVC--SKKGKILKREKEFEYAEEVLimkSDIEEKSRTILDLQIRVKELQIEND 707
Cdd:COG5185 100 QEYVNSLIKLPNYEWSADILIsllYLYKSEivALKDELIKVEKLDEIADIEA---SYGEVETGIIKDIFGKLTQELNQNL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 708 YQLRLKDMSCYEKiKELEETFTQELESLKNKHQILQAEKDNQEmqhqlqlSELMNKHAKEMRDLEsdsNQKLLMENEKYQ 787
Cdd:COG5185 177 KKLEIFGLTLGLL-KGISELKKAEPSGTVNSIKESETGNLGSE-------STLLEKAKEIINIEE---ALKGFQDPESEL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 788 ElqvDSQRMQEEYEKqlhnlqesknrTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDReiQDIKI 867
Cdd:COG5185 246 E---DLAQTSDKLEK-----------LVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKS--IDIKK 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 868 KYERW---------------LIEEKESNLQ-LKGEIgvmNKRLNSLQKELKERNNDIEDMKLEQQnlqgiIKSLEKDISM 931
Cdd:COG5185 310 ATESLeeqlaaaeaeqeleeSKRETETGIQnLTAEI---EQGQESLTENLEAIKEEIENIVGEVE-----LSKSSEELDS 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 932 LNTNIEKRTNTIQEKEKhiyDLKKKNQE----LEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENT 1007
Cdd:COG5185 382 FKDTIESTKESLDEIPQ---NQRGYAQEilatLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREAD 458
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 1008 QLKLniTQLQQKLKATDNELHKERQKKQNMEALIKRFKmdlhncvgfiqdyKKLKAGIRELYTKYVQQLEMV 1079
Cdd:COG5185 459 EESQ--SRLEEAYDEINRSVRSKKEDLNEELTQIESRV-------------STLKATLEKLRAKLERQLEGV 515
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
469-668 |
3.36e-10 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 63.78 E-value: 3.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 469 SFSNGGHLFAAVNGNVIQIYSCTTFENTNNLKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWNLSTGKREMECVLTSCIY 548
Cdd:COG2319 44 ASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 549 SSIALHSDSKIIFAVGSDQTLK--EISESSVHHEVPAFDVVYTAVAVSHSGDMVFVGTSLGTVRSmkYPLPLCRDFNEYQ 626
Cdd:COG2319 124 RSVAFSPDGKTLASGSADGTVRlwDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRL--WDLATGKLLRTLT 201
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2024426573 627 AHAGAITKMSVTNDDLFLLTASEDGSIFFWKVcsKKGKILKR 668
Cdd:COG2319 202 GHTGAVRSVAFSPDGKLLASGSADGTVRLWDL--ATGKLLRT 241
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
718-1032 |
3.61e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 3.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 718 YEKIKELEETFtqELESLKNKHQILQAEKDNQEMQHQLQLSELmNKHAKEMRDLESDSNQkllmENEKYQELQVDSQRMQ 797
Cdd:COG1196 215 YRELKEELKEL--EAELLLLKLRELEAELEELEAELEELEAEL-EELEAELAELEAELEE----LRLELEELELELEEAQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 798 EEY---EKQLHNLQESKNRTVEELTDYYE--EKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDikikyerw 872
Cdd:COG1196 288 AEEyelLAELARLEQDIARLEERRRELEErlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE-------- 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 873 LIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYD 952
Cdd:COG1196 360 LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 953 LKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQ 1032
Cdd:COG1196 440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
794-1155 |
9.55e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.16 E-value: 9.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 794 QRMQEEYEKQLHNLQESKNRTVE------ELTDY-YEEKLNEKSLLLEEAEEdMRQQLQAHEEIKKQIEEdedrEIQDIK 866
Cdd:TIGR02169 190 DLIIDEKRQQLERLRREREKAERyqallkEKREYeGYELLKEKEALERQKEA-IERQLASLEEELEKLTE----EISELE 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 867 IKYERWLIEEKESNLQLK----GEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKrtnt 942
Cdd:TIGR02169 265 KRLEEIEQLLEELNKKIKdlgeEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEE---- 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 943 iqekekhiydlkkknqelekfkfvLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKA 1022
Cdd:TIGR02169 341 ------------------------LEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1023 TDNELHKERQKKQNMEALIKRFKMDLHNcvgFIQDYKKLKAGIRELytkyvqqlemvemEEVDTDLQQEYMRQREYLERN 1102
Cdd:TIGR02169 397 LKREINELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINEL-------------EEEKEDKALEIKKQEWKLEQL 460
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 1103 LAALKKkvvkdqevHQAAYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSA 1155
Cdd:TIGR02169 461 AADLSK--------YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEER 505
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
719-1037 |
1.06e-09 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 62.56 E-value: 1.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEETFTQ--ELES----LKNKHQILQAEKDNQEMQHQLQ-----LSELMNKHAKEMRDLESDSNQkllMENEKYQ 787
Cdd:pfam06160 153 KQLAEIEEEFSQfeELTEsgdyLEAREVLEKLEEETDALEELMEdipplYEELKTELPDQLEELKEGYRE---MEEEGYA 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 788 --ELQVDSQRmqEEYEKQLHNLQEsknrTVEELT-DYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDR---- 860
Cdd:pfam06160 230 leHLNVDKEI--QQLEEQLEENLA----LLENLElDEAEEALEEIEERIDQLYDLLEKEVDAKKYVEKNLPEIEDYleha 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 861 --EIQDIKIKYER----WLIEEKESNLQLKGEigvmnKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDIsmlnT 934
Cdd:pfam06160 304 eeQNKELKEELERvqqsYTLNENELERVRGLE-----KQLEELEKRYDEIVERLEEKEVAYSELQEELEEILEQL----E 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 935 NIEKRTNTIQEKEKHIY-DLKKKNQELEKFKFVLdHRIeqfKKQIESRE-----NDIkimQKQIHEMERELEQLHKENTQ 1008
Cdd:pfam06160 375 EIEEEQEEFKESLQSLRkDELEAREKLDEFKLEL-REI---KRLVEKSNlpglpESY---LDYFFDVSDEIEDLADELNE 447
|
330 340
....*....|....*....|....*....
gi 2024426573 1009 LKLNITQLQQKLKATDNELHKERQKKQNM 1037
Cdd:pfam06160 448 VPLNMDEVNRLLDEAQDDVDTLYEKTEEL 476
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
940-1178 |
1.46e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.32 E-value: 1.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 940 TNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQK 1019
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1020 LkatdnelhkERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIREL-YTKYVQQLEMVEMEEVDTDlQQEYMRQREY 1098
Cdd:COG4942 99 L---------EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLqYLKYLAPARREQAEELRAD-LAELAALRAE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1099 LERNLAALkKKVVKDQEVHQAAYTRIMQENVSLI----KEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNET 1174
Cdd:COG4942 169 LEAERAEL-EALLAELEEERAALEALKAERQKLLarleKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
|
....
gi 2024426573 1175 LSSP 1178
Cdd:COG4942 248 FAAL 251
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
849-1155 |
1.52e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.39 E-value: 1.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 849 EIKKQIEEDEDREiqdiKIKYERWLIEEKESNlqlkgeigvmNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKD 928
Cdd:PRK03918 136 EIDAILESDESRE----KVVRQILGLDDYENA----------YKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKE 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 929 ISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKfvldHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQ 1008
Cdd:PRK03918 202 LEEVLREINEISSELPELREELEKLEKEVKELEELK----EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEE 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1009 LKLNITQLQQ-KLKATD----NELHKE-RQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMVEME 1082
Cdd:PRK03918 278 LEEKVKELKElKEKAEEyiklSEFYEEyLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL 357
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024426573 1083 EVDTDLQQEYMRQREYLERNLAALK----KKVVKDQEVHQAAYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSA 1155
Cdd:PRK03918 358 EERHELYEEAKAKKEELERLKKRLTgltpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA 434
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
882-1048 |
1.60e-09 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 59.55 E-value: 1.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 882 QLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKrtntIQEKEKHIydlkKKNQELE 961
Cdd:COG1579 21 RLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKK----YEEQLGNV----RNNKEYE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 962 kfkfVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQK-KQNMEAL 1040
Cdd:COG1579 93 ----ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEElEAEREEL 168
|
....*...
gi 2024426573 1041 IKRFKMDL 1048
Cdd:COG1579 169 AAKIPPEL 176
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
837-1217 |
1.61e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 62.35 E-value: 1.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 837 EEDMRQQLQAheeIKKQIEEDEDrEIQDIkikyERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQ 916
Cdd:TIGR04523 35 EKQLEKKLKT---IKNELKNKEK-ELKNL----DKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 917 NLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYD----LKKKNQELEKfkfvLDHRIEQFKKQIESRENDIKIMQKQI 992
Cdd:TIGR04523 107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKflteIKKKEKELEK----LNNKYNDLKKQKEELENELNLLEKEK 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 993 HEMERELEQLHKE-----------------NTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFI 1055
Cdd:TIGR04523 183 LNIQKNIDKIKNKllklelllsnlkkkiqkNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQ 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1056 QDYKK-LKAGIREL---------YTKYVQQLEMvEMEEVDTDLQQEYMRQreyLERNLAALKKKVVKDQevhqaayTRIM 1125
Cdd:TIGR04523 263 NKIKKqLSEKQKELeqnnkkikeLEKQLNQLKS-EISDLNNQKEQDWNKE---LKSELKNQEKKLEEIQ-------NQIS 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1126 QEN---VSLIKEINDLRQELTVAHTQVHDLQSalKLTKKKQAIQDTAPSNETLSSpAVLRLNAQKENekiIEMQLLEIQH 1202
Cdd:TIGR04523 332 QNNkiiSQLNEQISQLKKELTNSESENSEKQR--ELEEKQNEIEKLKKENQSYKQ-EIKNLESQIND---LESKIQNQEK 405
|
410
....*....|....*
gi 2024426573 1203 LRDQVQEKGQGLEAQ 1217
Cdd:TIGR04523 406 LNQQKDEQIKKLQQE 420
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
661-1038 |
1.72e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.47 E-value: 1.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 661 KKGKILKREKEFEYAEEVLIMKSDIEEKSRTILDLQIRVKELQIENDYQLRLKDMSCYEKIKELEETFTQELESLKNKHQ 740
Cdd:PTZ00121 1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ 1637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 741 ILQAEKDNQEMQHQLQLSELMN--KHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEK----QLHNLQESKNRT 814
Cdd:PTZ00121 1638 LKKKEAEEKKKAEELKKAEEENkiKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAkkaeELKKKEAEEKKK 1717
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 815 VEELTDYYEEKLNEKSLLLEEAEEDMRQQlqahEEIKKqiEEDEDREIQDIKIKyerwliEEKESNLQLKGEIGVMNKRL 894
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEAEEDKKKA----EEAKK--DEEEKKKIAHLKKE------EEKKAEEIRKEKEAVIEEEL 1785
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 895 NslQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLD------ 968
Cdd:PTZ00121 1786 D--EEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNnenged 1863
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 969 -HRIEQFKKQIESRENDIKIMqkqihEMERELEQLHKENTQLKLNITQLQQK-LKATDNELHKERQKKQNME 1038
Cdd:PTZ00121 1864 gNKEADFNKEKDLKEDDEEEI-----EEADEIEKIDKDDIEREIPNNNMAGKnNDIIDDKLDKDEYIKRDAE 1930
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
892-1110 |
2.28e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 60.93 E-value: 2.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 892 KRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKfkfVLDHRI 971
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA---ELEAQK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 972 EQFKKQI-----ESRENDIKIM--QKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRF 1044
Cdd:COG4942 104 EELAELLralyrLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024426573 1045 KMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEmvEMEEVDTDLQQEYMRqreyLERNLAALKKKV 1110
Cdd:COG4942 184 EEERAALEALKAERQKLLARLEKELAELAAELA--ELQQEAEELEALIAR----LEAEAAAAAERT 243
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
720-1163 |
2.63e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 61.73 E-value: 2.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 720 KIKELEETFTQELESLKNKHQILQAEKDnqEMQHQLQLSELMNKHAKEMR---------------DLESdsnqKLLMENE 784
Cdd:pfam01576 16 KVKERQQKAESELKELEKKHQQLCEEKN--ALQEQLQAETELCAEAEEMRarlaarkqeleeilhELES----RLEEEEE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 785 KYQELQVDSQRMQ----------EEYEKQLHNLQ------ESKNRTVEE---LTDYYEEKLNEKSLLLEEAEEDMRQQLQ 845
Cdd:pfam01576 90 RSQQLQNEKKKMQqhiqdleeqlDEEEAARQKLQlekvttEAKIKKLEEdilLLEDQNSKLSKERKLLEERISEFTSNLA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 846 AHEEIKKQ-----------IEEDEDR---------EIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERN 905
Cdd:pfam01576 170 EEEEKAKSlsklknkheamISDLEERlkkeekgrqELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 906 NDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLkkkNQELEKFKFVLDHRIEQFKKQIE---SRE 982
Cdd:pfam01576 250 ARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDL---GEELEALKTELEDTLDTTAAQQElrsKRE 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 983 NDIKIMQKQIHEMER-------ELEQLHKE-----NTQL------KLNITQLQQKLKATDNELHKE----RQKKQNMEAL 1040
Cdd:pfam01576 327 QEVTELKKALEEETRsheaqlqEMRQKHTQaleelTEQLeqakrnKANLEKAKQALESENAELQAElrtlQQAKQDSEHK 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1041 IKRFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMVemeevdTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQ-- 1118
Cdd:pfam01576 407 RKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESV------SSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQee 480
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 1119 -----AAYTRIMQ---ENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQ 1163
Cdd:pfam01576 481 trqklNLSTRLRQledERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKL 533
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
819-1141 |
2.83e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 61.91 E-value: 2.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 819 TDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREiqDIKIKYERWLIEEK-ESNLQLKGEIGVMNKRLNSL 897
Cdd:pfam02463 165 SRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAK--KALEYYQLKEKLELeEEYLLYLDYLKLNEERIDLL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 898 QKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMlntniEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQ 977
Cdd:pfam02463 243 QELLRDEQEEIESSKQEIEKEEEKLAQVLKENKE-----EEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLK 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 978 IESREND--IKIMQKQIHEMERELEQL--HKENTQLKLNI----TQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLH 1049
Cdd:pfam02463 318 ESEKEKKkaEKELKKEKEEIEELEKELkeLEIKREAEEEEeeelEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1050 NCVGFIQDYKKLKAGIRELY-----TKYVQQLEMVEMEEVDTDLQQEYMRQREYLERNLAA--LKKKVVKDQEVHQAAYT 1122
Cdd:pfam02463 398 ELKSEEEKEAQLLLELARQLedllkEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELklLKDELELKKSEDLLKET 477
|
330
....*....|....*....
gi 2024426573 1123 RIMQENVSLIKEINDLRQE 1141
Cdd:pfam02463 478 QLVKLQEQLELLLSRQKLE 496
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
706-1209 |
3.93e-09 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 61.61 E-value: 3.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 706 NDYQLRLKDMSCYEKIKELEETFTQELESLKNKHQILqaekdNQEMQHQL-QLSELMNK---HAKEMR----DLESDSNQ 777
Cdd:TIGR01612 1087 NEIKEKLKHYNFDDFGKEENIKYADEINKIKDDIKNL-----DQKIDHHIkALEEIKKKsenYIDEIKaqinDLEDVADK 1161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 778 KLLMEN----EKYQE---LQVDSQR-MQEEYEKQLHNLQE-SKNRT----VEELTDYYEEKLNekSLLLEEAEED----- 839
Cdd:TIGR01612 1162 AISNDDpeeiEKKIEnivTKIDKKKnIYDEIKKLLNEIAEiEKDKTsleeVKGINLSYGKNLG--KLFLEKIDEEkkkse 1239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 840 -----MRQQLQAHEEIKKQ---------IEEDEDREIQDIKI---KYERWLIEEKESN----------LQL------KGE 886
Cdd:TIGR01612 1240 hmikaMEAYIEDLDEIKEKspeienemgIEMDIKAEMETFNIshdDDKDHHIISKKHDenisdireksLKIiedfseESD 1319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 887 IGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKsLEKDISMLNtNIEKRTNTIQEKEKHIYDLKKKNQELEKfKFV 966
Cdd:TIGR01612 1320 INDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILK-LNKIKKIID-EVKEYTKEIEENNKNIKDELDKSEKLIK-KIK 1396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 967 LDHRIEQFKKQIESREND---------IKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNEL-HKERQKKQN 1036
Cdd:TIGR01612 1397 DDINLEECKSKIESTLDDkdidecikkIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSqHILKIKKDN 1476
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1037 ----MEALIKRFKMDLHNCVGFIQDYKKLKAGI---RELYTKYVQQLemvemeevdTDLQQEYMRqreylernlAALKKK 1109
Cdd:TIGR01612 1477 atndHDFNINELKEHIDKSKGCKDEADKNAKAIeknKELFEQYKKDV---------TELLNKYSA---------LAIKNK 1538
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1110 VVKDQevhqaaytrimQENVSLIKEINDLRQELTVAHTQVHdlQSALKLTKKKQAIQDTAPSNETlSSPAVLRLNAQKEN 1189
Cdd:TIGR01612 1539 FAKTK-----------KDSEIIIKEIKDAHKKFILEAEKSE--QKIKEIKKEKFRIEDDAAKNDK-SNKAAIDIQLSLEN 1604
|
570 580
....*....|....*....|
gi 2024426573 1190 ekiIEMQLLEIQHLRDQVQE 1209
Cdd:TIGR01612 1605 ---FENKFLKISDIKKKIND 1621
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
673-1064 |
5.28e-09 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 61.22 E-value: 5.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 673 EYAEEVLIMKSDIE---EKSRTIL---------DLQIRVKELQIENDYQLRLKDMS-----CYEKIKELEETFTQELESL 735
Cdd:TIGR01612 1447 ENNENVLLLFKNIEmadNKSQHILkikkdnatnDHDFNINELKEHIDKSKGCKDEAdknakAIEKNKELFEQYKKDVTEL 1526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 736 KNKHQILqaekdnqemqhqlqlsELMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEKQLHNLQESKNrtv 815
Cdd:TIGR01612 1527 LNKYSAL----------------AIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAK--- 1587
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 816 eeltdyyEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEeDEDREIQDIKIKYERWLIEEKESNLQLKGEigvmnkRLN 895
Cdd:TIGR01612 1588 -------NDKSNKAAIDIQLSLENFENKFLKISDIKKKIN-DCLKETESIEKKISSFSIDSQDTELKENGD------NLN 1653
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 896 SLQ---KELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKrtnTIQEKEKHIydLKKKNQELEKFKFVLDHRIE 972
Cdd:TIGR01612 1654 SLQeflESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEI---GIIEKIKEI--AIANKEEIESIKELIEPTIE 1728
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 973 QFKKQIESreNDIKIM--QKQIHEMERELEQLHKENTQL------------KLNIT--QLQQKLKATDNELHK--ERQKK 1034
Cdd:TIGR01612 1729 NLISSFNT--NDLEGIdpNEKLEEYNTEIGDIYEEFIELyniiagcletvsKEPITydEIKNTRINAQNEFLKiiEIEKK 1806
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 2024426573 1035 QN----------MEALIKRFKMDLHNC-VGFIQDYKKLKAG 1064
Cdd:TIGR01612 1807 SKsylddieakeFDRIINHFKKKLDHVnDKFTKEYSKINEG 1847
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
719-930 |
7.75e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.01 E-value: 7.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEetftQELESLKNKHQILQAEKDNQEMQHQLQLSEL------MNKHAKEMRDLESD---SNQKLLMENEKYQEL 789
Cdd:COG4942 20 DAAAEAE----AELEQLQQEIAELEKELAALKKEEKALLKQLaalerrIAALARRIRALEQElaaLEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 790 QVDSQRMQEEYEKQLHNLQESKNRtveeltDYYEEKLNEKSL--------LLEEAEEDMRQQLQAHEEIKKQIEEDEdRE 861
Cdd:COG4942 96 RAELEAQKEELAELLRALYRLGRQ------PPLALLLSPEDFldavrrlqYLKYLAPARREQAEELRADLAELAALR-AE 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 862 IQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDIS 930
Cdd:COG4942 169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
936-1179 |
1.08e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 936 IEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQ 1015
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1016 LQQKLKATDNELHkeRQKKQNMEALIKRFKmDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEmvEMEEVDTDLQQEYMRQ 1095
Cdd:COG4942 102 QKEELAELLRALY--RLGRQPPLALLLSPE-DFLDAVRRLQYLKYLAPARREQAEELRADLA--ELAALRAELEAERAEL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1096 REyLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETL 1175
Cdd:COG4942 177 EA-LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
|
....
gi 2024426573 1176 SSPA 1179
Cdd:COG4942 256 PWPV 259
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
661-1032 |
1.16e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.77 E-value: 1.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 661 KKGKILKREKEFEYAEEvliMKSDIEEKsRTILDLQIRVKELQIENDYQLRLKDMSCYEKIKELEETFTQELESLKNKHQ 740
Cdd:PTZ00121 1432 KADEAKKKAEEAKKADE---AKKKAEEA-KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAE 1507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 741 ILQAEKDNQEMQHQLQLSELMN-KHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEKQLHNLQESKNRTVEELT 819
Cdd:PTZ00121 1508 AKKKADEAKKAEEAKKADEAKKaEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK 1587
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 820 DYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIE-----EDEDREIQDIKIKYErwliEEKESNLQLKGEIGVMNKRL 894
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEelkkaEEEKKKVEQLKKKEA----EEKKKAEELKKAEEENKIKA 1663
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 895 NSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDismlntniekrtntiQEKEKHIYDLKKKNQELEKfkfvldhRIEQF 974
Cdd:PTZ00121 1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE---------------AEEAKKAEELKKKEAEEKK-------KAEEL 1721
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2024426573 975 KKQIESRENDIKIMQKQIHEMERELEQLHKENTQlKLNITQLQQKLKATDNELHKERQ 1032
Cdd:PTZ00121 1722 KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKE 1778
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
836-1043 |
1.39e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.24 E-value: 1.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 836 AEEDMRQQLQA-HEEIKKQIEEdedreiqdikikYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLE 914
Cdd:COG4942 17 AQADAAAEAEAeLEQLQQEIAE------------LEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 915 QQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIY--------DLKKKNQELEKFKFVLDHRIEQF------KKQIES 980
Cdd:COG4942 85 LAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPlalllspeDFLDAVRRLQYLKYLAPARREQAeelradLAELAA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024426573 981 RENDIKIMQKQIHEMERELEQLHKENTQLKLN----ITQLQQKLKATDNELHKERQKKQNMEALIKR 1043
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAErqklLARLEKELAELAAELAELQQEAEELEALIAR 231
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
676-1077 |
1.77e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.98 E-value: 1.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 676 EEVLIMKSDIEEKSRTILDL--QIRVKELQIEndyqlrlKDMSCYEKIKELEETFTQELESLKNKHQIL---QAEKD--N 748
Cdd:pfam15921 482 EELTAKKMTLESSERTVSDLtaSLQEKERAIE-------ATNAEITKLRSRVDLKLQELQHLKNEGDHLrnvQTECEalK 554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 749 QEMQHQLQLSELMNKHAKEMRDLESDSNQKL-LMENEKYQ-ELQVDSQRMQEEYEKQLHNLQESKNRTVE-ELTDYYEEK 825
Cdd:pfam15921 555 LQMAEKDKVIEILRQQIENMTQLVGQHGRTAgAMQVEKAQlEKEINDRRLELQEFKILKDKKDAKIRELEaRVSDLELEK 634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 826 LNekslLLEEAEEDMRQqlqaheeikkqieededreIQDIKikyerwliEEKEsnlQLKGEIGVMNKRLNSLQK--ELKE 903
Cdd:pfam15921 635 VK----LVNAGSERLRA-------------------VKDIK--------QERD---QLLNEVKTSRNELNSLSEdyEVLK 680
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 904 RN--NDIEDMKLEQQNLQGIIKSLEKDismlntnIEKRTNTIQEKEkhiydlkkkNQELEKFKFVLDhrieqFKKQIESR 981
Cdd:pfam15921 681 RNfrNKSEEMETTTNKLKMQLKSAQSE-------LEQTRNTLKSME---------GSDGHAMKVAMG-----MQKQITAK 739
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 982 ENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHK-----------ERQKKQ---NMEALIKRFKMD 1047
Cdd:pfam15921 740 RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmagelevlrsqERRLKEkvaNMEVALDKASLQ 819
|
410 420 430
....*....|....*....|....*....|
gi 2024426573 1048 LHNCVGFIQDYKKLKAGIRELYTKYVQQLE 1077
Cdd:pfam15921 820 FAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
770-1216 |
1.91e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.98 E-value: 1.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 770 DLESDSNQKLLMENEKYQelqvdSQRMQEEYEKQLHNLQESKNRTvEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEE 849
Cdd:pfam15921 58 EVELDSPRKIIAYPGKEH-----IERVLEEYSHQVKDLQRRLNES-NELHEKQKFYLRQSVIDLQTKLQEMQMERDAMAD 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 850 IKK---QIEEDEDREIQDI--KIKYERWLIEE--KESNLQLKGEIGVMNKRLNSLQkELKERNNDIEDMK----LEQQNL 918
Cdd:pfam15921 132 IRRresQSQEDLRNQLQNTvhELEAAKCLKEDmlEDSNTQIEQLRKMMLSHEGVLQ-EIRSILVDFEEASgkkiYEHDSM 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 919 QGI-IKSLEKDISMLntniekrtntIQEKEKHIYDLKKK----NQELEKFKFVLDHRIEQFKKQIESRendikiMQKQIH 993
Cdd:pfam15921 211 STMhFRSLGSAISKI----------LRELDTEISYLKGRifpvEDQLEALKSESQNKIELLLQQHQDR------IEQLIS 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 994 EMERELEQLHKENTQLKLNITQLQQKLkatdnELHKERQKKQNmeALIKRFKMDLHNCVgfiqdyKKLKAGIRE---LYT 1070
Cdd:pfam15921 275 EHEVEITGLTEKASSARSQANSIQSQL-----EIIQEQARNQN--SMYMRQLSDLESTV------SQLRSELREakrMYE 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1071 KYVQQLEM------VEMEEVDTD---LQQEYMRQREYLERNLAALKKKvVKDQEVHQAAYTRIMQENVSLIKEINDLRQE 1141
Cdd:pfam15921 342 DKIEELEKqlvlanSELTEARTErdqFSQESGNLDDQLQKLLADLHKR-EKELSLEKEQNKRLWDRDTGNSITIDHLRRE 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1142 LTVAHTQVHDLQSALKLTKKK---------QAIQDTAPSNETLSSpavlrLNAQKENEKIIEMQLLE------------- 1199
Cdd:pfam15921 421 LDDRNMEVQRLEALLKAMKSEcqgqmerqmAAIQGKNESLEKVSS-----LTAQLESTKEMLRKVVEeltakkmtlesse 495
|
490
....*....|....*....
gi 2024426573 1200 --IQHLRDQVQEKGQGLEA 1216
Cdd:pfam15921 496 rtVSDLTASLQEKERAIEA 514
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
818-1034 |
1.93e-08 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 58.49 E-value: 1.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 818 LTDYYEEkLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYErwliEEKESNLQLKGEIGVMNKRLNSL 897
Cdd:PHA02562 172 NKDKIRE-LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYD----ELVEEAKTIKAEIEELTDELLNL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 898 QKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTN----------------IEKRTNTIQEKEKHIYDLKKKNQELE 961
Cdd:PHA02562 247 VMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptctqqisegpdrITKIKDKLKELQHSLEKLDTAIDELE 326
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024426573 962 KFKFVLDH---RIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKK 1034
Cdd:PHA02562 327 EIMDEFNEqskKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEK 402
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
662-1210 |
2.80e-08 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 58.69 E-value: 2.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 662 KGKILKREKEFeyAEEVLIMKSDIEEKSRTILDLQIRVKELQIENDYQlrlkdmscYEKIKELEETFTQELESLKNKHQI 741
Cdd:PTZ00440 786 KDTILNKENKI--SNDINILKENKKNNQDLLNSYNILIQKLEAHTEKN--------DEELKQLLQKFPTEDENLNLKELE 855
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 742 LQAEKDNQEMQHQLQLSELMNKHAKEMRDLE-----SDSNQKL---LMEN---------EKYQELQVDSQRMQEEYEKQL 804
Cdd:PTZ00440 856 KEFNENNQIVDNIIKDIENMNKNINIIKTLNiainrSNSNKQLvehLLNNkidlknkleQHMKIINTDNIIQKNEKLNLL 935
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 805 HNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKyerwlIEEKESNLQlk 884
Cdd:PTZ00440 936 NNLNKEKEKIEKQLSDTKINNLKMQIEKTLEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSE-----IDKLNVNYN-- 1008
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 885 geigVMNKRLNSLQKE------------LKERNNDIEDmKLEQ--QNLQGI---IKSLEKDISMLNTNIEKRTNTIQEKE 947
Cdd:PTZ00440 1009 ----ILNKKIDDLIKKqhddiielidklIKEKGKEIEE-KVDQyiSLLEKMktkLSSFHFNIDIKKYKNPKIKEEIKLLE 1083
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 948 KHIYDL----KKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKEntqlklnitqlqqkLKAT 1023
Cdd:PTZ00440 1084 EKVEALlkkiDENKNKLIEIKNKSHEHVVNADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKE--------------LENM 1149
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1024 DNELHKErQKKQNMEALIKRFKMDLhnCVGFIQDYKKLKAGIRELYTKYVQQLEMVEMEEVDTdlQQEYMRQREYLE--R 1101
Cdd:PTZ00440 1150 NLEDITL-NEVNEIEIEYERILIDH--IVEQINNEAKKSKTIMEEIESYKKDIDQVKKNMSKE--RNDHLTTFEYNAyyD 1224
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1102 NLAALKKKVVK-DQEVHQAAYTRIMQENVSLIKEIN-DLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSSpa 1179
Cdd:PTZ00440 1225 KATASYENIEElTTEAKGLKGEANRSTNVDELKEIKlQVFSYLQQVIKENNKMENALHEIKNMYEFLISIDSEKILKE-- 1302
|
570 580 590
....*....|....*....|....*....|..
gi 2024426573 1180 VLRLNAQKEN-EKIIEMQLLEIQHLRDQVQEK 1210
Cdd:PTZ00440 1303 ILNSTKKAEEfSNDAKKELEKTDNLIKQVEAK 1334
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
719-990 |
2.89e-08 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 58.37 E-value: 2.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEETFTQELESLKNK--HQILQAEKDNQEMQHQLQLSELMNKhaKEMRDLESDSNQkllMENEKYQ--ELQVDSQ 794
Cdd:PRK01156 465 EKSNHIINHYNEKKSRLEEKirEIEIEVKDIDEKIVDLKKRKEYLES--EEINKSINEYNK---IESARADleDIKIKIN 539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 795 RMQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQlqaHEEIKKQIEEDEDReIQDIKIKYErwli 874
Cdd:PRK01156 540 ELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSR---SNEIKKQLNDLESR-LQEIEIGFP---- 611
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 875 eekESNLQLKGEIGVMNKRLNSLQKELKErnndIEDMKLEQQNLQGIIKSLEKDISMLNtNIEKRTNTIQEKEKHIYD-L 953
Cdd:PRK01156 612 ---DDKSYIDKSIREIENEANNLNNKYNE----IQENKILIEKLRGKIDNYKKQIAEID-SIIPDLKEITSRINDIEDnL 683
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2024426573 954 KKKNQELEKFKF----------VLDHRIEQFKKQIESRENDIKIMQK 990
Cdd:PRK01156 684 KKSRKALDDAKAnrarlestieILRTRINELSDRINDINETLESMKK 730
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
874-1068 |
3.81e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.08 E-value: 3.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 874 IEEKESNL-QLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYD 952
Cdd:COG4942 22 AAEAEAELeQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 953 LKK----------KNQELEKFKFVL--------DHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNIT 1014
Cdd:COG4942 102 QKEelaellralyRLGRQPPLALLLspedfldaVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2024426573 1015 QLQQKLKATDNElhkERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIREL 1068
Cdd:COG4942 182 ELEEERAALEAL---KAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
688-1093 |
4.07e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.47 E-value: 4.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 688 KSRTILDLQIRVKELQIEndyQLRLKDMSCYEKIKELEETfTQELESLKNkhQILQAEKDNQEMQHQLQLSELMNKHAKE 767
Cdd:COG4717 64 RKPELNLKELKELEEELK---EAEEKEEEYAELQEELEEL-EEELEELEA--ELEELREELEKLEKLLQLLPLYQELEAL 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 768 MRDLESDSNQ--KLLMENEKYQELQVDsqrmQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEkslLLEEAEEDMRQQLQ 845
Cdd:COG4717 138 EAELAELPERleELEERLEELRELEEE----LEELEAELAELQEELEELLEQLSLATEEELQD---LAEELEELQQRLAE 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 846 AHEEIKKQIEEDEDREIQDIKIKYERWLIEEKESNLQLKGEIGVM----------------------------------- 890
Cdd:COG4717 211 LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAaallallglggsllsliltiagvlflvlgllallf 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 891 ---NKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQ------------EKEKHIYDLKK 955
Cdd:COG4717 291 lllAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEelqellreaeelEEELQLEELEQ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 956 KNQELEKFKFV-----LDHRIEQFKKQIEsRENDIKIMQKQIHEMERELEQLHKENT--QLKLNITQLQQKLKATDNELH 1028
Cdd:COG4717 371 EIAALLAEAGVedeeeLRAALEQAEEYQE-LKEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELE 449
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024426573 1029 KERQKKQNMEALIKRFKMDlHNCVGFIQDYKKLKAGIRELYTKY-VQQLEMVEMEEVDTDLQQEYM 1093
Cdd:COG4717 450 ELREELAELEAELEQLEED-GELAELLQELEELKAELRELAEEWaALKLALELLEEAREEYREERL 514
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
662-1108 |
5.89e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 57.54 E-value: 5.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 662 KGKILKREKEFEYAEEVLI----MKSDIEEKSRTILDLQIRVKELQIENDYQLRLKDMSCYEKIKELeetfTQELESLKN 737
Cdd:pfam12128 240 RPEFTKLQQEFNTLESAELrlshLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDEL----NGELSAADA 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 738 KHQILQAEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQklLMENEKYQELQVDSQR-MQEEYEKQLHNLQESKNRTVE 816
Cdd:pfam12128 316 AVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSE--LENLEERLKALTGKHQdVTAKYNRRRSKIKEQNNRDIA 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 817 ELTDYYEEKLNEKSLLLEEAEEDMRQQLQA----HEEIKKQIEEDEDREIQDI--------KIKYERWLIEEKESNLQL- 883
Cdd:pfam12128 394 GIKDKLAKIREARDRQLAVAEDDLQALESElreqLEAGKLEFNEEEYRLKSRLgelklrlnQATATPELLLQLENFDERi 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 884 ---KGEIGVMNKRLNSLQKELK----------ERNNDIEDMKLEQQN------LQGIIKS------LEKDISMLNTNIEK 938
Cdd:pfam12128 474 eraREEQEAANAEVERLQSELRqarkrrdqasEALRQASRRLEERQSaldeleLQLFPQAgtllhfLRKEAPDWEQSIGK 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 939 --------RTNTIQE-------KEKHIYDLKKKNQELEKFKFV-----LDHRIEQFKKQIESRENDIKIMQKQIHEMERE 998
Cdd:pfam12128 554 vispellhRTDLDPEvwdgsvgGELNLYGVKLDLKRIDVPEWAaseeeLRERLDKAEEALQSAREKQAAAEEQLVQANGE 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 999 LEQLHKENT-------QLKLNITQL---QQKLKATDNELHKERQKKQNME--ALIKRFKMDLHNCVGFIQDYKKLKagiR 1066
Cdd:pfam12128 634 LEKASREETfartalkNARLDLRRLfdeKQSEKDKKNKALAERKDSANERlnSLEAQLKQLDKKHQAWLEEQKEQK---R 710
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 2024426573 1067 ELYTKYVQQLEMVEMEEVDTD--LQQEYMRQREYLERNLAALKK 1108
Cdd:pfam12128 711 EARTEKQAYWQVVEGALDAQLalLKAAIAARRSGAKAELKALET 754
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
722-1118 |
5.92e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 57.36 E-value: 5.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 722 KELEETF------TQELESLKNKHQILQAEKDN-QEMQHQLQLSELMNKHAKEMRD-LESDSNQkllmenekyqelQVDS 793
Cdd:TIGR00606 169 KALKQKFdeifsaTRYIKALETLRQVRQTQGQKvQEHQMELKYLKQYKEKACEIRDqITSKEAQ------------LESS 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 794 QRMQEEYEKQLHNLQESKNRTVEELTDYYeeKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWL 873
Cdd:TIGR00606 237 REIVKSYENELDPLKNRLKEIEHNLSKIM--KLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTV 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 874 IEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIE----KRTNTIQEKEKH 949
Cdd:TIGR00606 315 REKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLEldgfERGPFSERQIKN 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 950 IYDLKKKNQELE-----KFKFVLDHRIEQFKKQIESRENDIKIMQKQIhemERELEQLHKENTQLKLNITQLQQKLKATD 1024
Cdd:TIGR00606 395 FHTLVIERQEDEaktaaQLCADLQSKERLKQEQADEIRDEKKGLGRTI---ELKKEILEKKQEELKFVIKELQQLEGSSD 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1025 NELHKERQKKQNMEALIKRFKMDLHNCVgfIQDYKKLKAGIRELYTKYVQQLEmvEMEEVDtdlqqeymRQREYLERNLA 1104
Cdd:TIGR00606 472 RILELDQELRKAERELSKAEKNSLTETL--KKEVKSLQNEKADLDRKLRKLDQ--EMEQLN--------HHTTTRTQMEM 539
|
410
....*....|....
gi 2024426573 1105 ALKKKVVKDQEVHQ 1118
Cdd:TIGR00606 540 LTKDKMDKDEQIRK 553
|
|
| Rabaptin |
pfam03528 |
Rabaptin; |
694-1158 |
6.68e-08 |
|
Rabaptin;
Pssm-ID: 367545 [Multi-domain] Cd Length: 486 Bit Score: 56.65 E-value: 6.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 694 DLQIRVKELQIENDYQLRLK---DMSCYEKIKELEETFTQELESLKNKHQILQAEKDnqemqhqlQLSELMNKHAKEMRD 770
Cdd:pfam03528 5 DLQQRVAELEKENAEFYRLKqqlEAEFNQKRAKFKELYLAKEEDLKRQNAVLQEAQV--------ELDALQNQLALARAE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 771 LESDSNQKLLMENEKYQELQVDSQRMQEEyekqLHNLQESKNRTVEELTDYYEEKLNEKsllleeaeedmRQQLQaheei 850
Cdd:pfam03528 77 MENIKAVATVSENTKQEAIDEVKSQWQEE----VASLQAIMKETVREYEVQFHRRLEQE-----------RAQWN----- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 851 kkQIEEDEDREIQDIKikyeRWLIEEKESNlqlkgeigvmnkrlnSLQKELKERNNDIEdmkleqqNLQGIIKSLEKDIS 930
Cdd:pfam03528 137 --QYRESAEREIADLR----RRLSEGQEEE---------------NLEDEMKKAQEDAE-------KLRSVVMPMEKEIA 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 931 MLNTNIEKRTNTIQEKEKHiyDLKKKNQELEKFKFV---LDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENT 1007
Cdd:pfam03528 189 ALKAKLTEAEDKIKELEAS--KMKELNHYLEAEKSCrtdLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHN 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1008 QLKlnitqlQQKLKATDNELHKERQKKQNMealiKRFKMDLHNcvgfiqdykklkagirelytkyvQQLEMVemEEVDTD 1087
Cdd:pfam03528 267 QLK------HTWQKANDQFLESQRLLMRDM----QRMESVLTS-----------------------EQLRQV--EEIKKK 311
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024426573 1088 LQQEYMRQREYLERNlaALKKKVVKDQEVHQAAYTRIMQENVSLIKEindlRQELTVAHTQVHDLQSALKL 1158
Cdd:pfam03528 312 DQEEHKRARTHKEKE--TLKSDREHTVSIHAVFSPAGVETSAPLSNV----EEQINSAHGSVHSLDTDVVL 376
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
662-1045 |
6.99e-08 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 57.22 E-value: 6.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 662 KGKILKREKEFEYAEEVLIMKSDIEEKSRTILDLQIRVKELQ-IENDYQLRLKDmscYEKIKELEETFTQELESLKN--- 737
Cdd:PRK01156 318 DAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEgYEMDYNSYLKS---IESLKKKIEEYSKNIERMSAfis 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 738 ---KHQILQAEKDNQE--------MQHQLQLSELmNKHAKEMRDLESDSNQKLLMENEKYQ------ELQVD-SQRMQEE 799
Cdd:PRK01156 395 eilKIQEIDPDAIKKElneinvklQDISSKVSSL-NQRIRALRENLDELSRNMEMLNGQSVcpvcgtTLGEEkSNHIINH 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 800 YEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKK---QIEEDEDR--EIQDIKIKYERwLI 874
Cdd:PRK01156 474 YNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESaraDLEDIKIKinELKDKHDKYEE-IK 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 875 EEKESNlqlkgEIGVMNKRLNSLQKELKERNN-DIEDMKLEQQNLQGIIKSLEKDISMLNTNIEK----RTNTIQEKEKH 949
Cdd:PRK01156 553 NRYKSL-----KLEDLDSKRTSWLNALAVISLiDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDdksyIDKSIREIENE 627
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 950 IYDLKKKNQELEKFKFVLDH---RIEQFKKQI---ESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKAT 1023
Cdd:PRK01156 628 ANNLNNKYNEIQENKILIEKlrgKIDNYKKQIaeiDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEIL 707
|
410 420
....*....|....*....|..
gi 2024426573 1024 DNELHKERQKKQNMEALIKRFK 1045
Cdd:PRK01156 708 RTRINELSDRINDINETLESMK 729
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
665-1090 |
8.81e-08 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 57.15 E-value: 8.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 665 ILKREKEFEYAEEVLIMKSDIEEKSRTILDLQIrvkeLQIENDYqlrlkdmscYEKIKELEETFTQE---LESLKNKHQI 741
Cdd:PTZ00440 409 ISLSEHTLKAAEDVLKENSQKIADYALYSNLEI----IEIKKKY---------DEKINELKKSINQLktlISIMKSFYDL 475
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 742 LQAEKDNQE---------MQHQLQLSELMN--KHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEKQLHNLQES 810
Cdd:PTZ00440 476 IISEKDSMDskekkessdSNYQEKVDELLQiiNSIKEKNNIVNNNFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETL 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 811 KNRtvEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIE-------------EDEDREIQDIKIKYERWLIEEK 877
Cdd:PTZ00440 556 IKD--EKLKRSMKNDIKNKIKYIEENVDHIKDIISLNDEIDNIIQqieelinealfnkEKFINEKNDLQEKVKYILNKFY 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 878 ESNLQL---------------------KGEIGVMNKRLNSLQKELKERNND-----IEDMKLEQQNLQGIIKSL-EKDIS 930
Cdd:PTZ00440 634 KGDLQElldelshflddhkylyheaksKEDLQTLLNTSKNEYEKLEFMKSDnidniIKNLKKELQNLLSLKENIiKKQLN 713
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 931 MLNTNIEKRTNTIQEKEKhiyDLKKKNQELEKFKfvldHRIEQFKKQIESRENDIKImqkQIHEMERELEQLHKENTQLK 1010
Cdd:PTZ00440 714 NIEQDISNSLNQYTIKYN---DLKSSIEEYKEEE----EKLEVYKHQIINRKNEFIL---HLYENDKDLPDGKNTYEEFL 783
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1011 LNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLhncvgfiqdyKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQ 1090
Cdd:PTZ00440 784 QYKDTILNKENKISNDINILKENKKNNQDLLNSYNILI----------QKLEAHTEKNDEELKQLLQKFPTEDENLNLKE 853
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
657-1215 |
1.30e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 56.21 E-value: 1.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 657 KVCSKKGKILKREKEFEYAEEVLIMKSD-----------IEEKSRTILDLQIRVK-----ELQIEND-YQLRLKDMSCY- 718
Cdd:TIGR00606 218 KACEIRDQITSKEAQLESSREIVKSYENeldplknrlkeIEHNLSKIMKLDNEIKalksrKKQMEKDnSELELKMEKVFq 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 ---EKIKELEETFTQELESLKNKHQILQAE--KDNQEMQHQLQ-LSELMNKHAK-----EMRDLESDSNQKLLMENEKYQ 787
Cdd:TIGR00606 298 gtdEQLNDLYHNHQRTVREKERELVDCQREleKLNKERRLLNQeKTELLVEQGRlqlqaDRHQEHIRARDSLIQSLATRL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 788 ELQV-----DSQRMQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQqLQAHEEIKKQIEEDEDREI 862
Cdd:TIGR00606 378 ELDGfergpFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKG-LGRTIELKKEILEKKQEEL 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 863 QDIKIKYERW------LIEEKESNLQLKGEIGVMNKrlNSLQKELKERnndIEDMKLEQQNLQGIIKSLEKDISMLNTNI 936
Cdd:TIGR00606 457 KFVIKELQQLegssdrILELDQELRKAERELSKAEK--NSLTETLKKE---VKSLQNEKADLDRKLRKLDQEMEQLNHHT 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 937 EKRTNTIQ------EKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLK 1010
Cdd:TIGR00606 532 TTRTQMEMltkdkmDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHIN 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1011 LNITQLQQKLKATDNELHkERQKKQNMEALIKRFKMDLHNCvgfiQDYKKLKAGIRELYTKYVQQLEM------------ 1078
Cdd:TIGR00606 612 NELESKEEQLSSYEDKLF-DVCGSQDEESDLERLKEEIEKS----SKQRAMLAGATAVYSQFITQLTDenqsccpvcqrv 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1079 ----VEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRimQENVSLI-KEINDLRQELTVAHTQVHDLQ 1153
Cdd:TIGR00606 687 fqteAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR--QSIIDLKeKEIPELRNKLQKVNRDIQRLK 764
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024426573 1154 SALKLTKKK-QAIQDTAPSNETLSSPAVL--RLNAQ-KENEKIIEMQL---------LEIQHLRDQVQEKGQGLE 1215
Cdd:TIGR00606 765 NDIEEQETLlGTIMPEEESAKVCLTDVTImeRFQMElKDVERKIAQQAaklqgsdldRTVQQVNQEKQEKQHELD 839
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
813-1045 |
1.92e-07 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 55.41 E-value: 1.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 813 RTVEELTDYY-EEKLNEKSLLLEEAEEDMRQQLqahEEIKKQIEEDEdREIQDIKikyerwlieEKESNLQLKGEIGVMN 891
Cdd:COG3206 152 AVANALAEAYlEQNLELRREEARKALEFLEEQL---PELRKELEEAE-AALEEFR---------QKNGLVDLSEEAKLLL 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 892 KRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNiekrtNTIQEKEKHIYDLKKKNQELEKfKFVLDH-- 969
Cdd:COG3206 219 QQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQS-----PVIQQLRAQLAELEAELAELSA-RYTPNHpd 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 970 ------RIEQFKKQIESR--------ENDIKIMQKQIHEMERELEQLHKENTQLKLN---ITQLQQKLKAtdnelhkerq 1032
Cdd:COG3206 293 vialraQIAALRAQLQQEaqrilaslEAELEALQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEV---------- 362
|
250
....*....|...
gi 2024426573 1033 KKQNMEALIKRFK 1045
Cdd:COG3206 363 ARELYESLLQRLE 375
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
882-1202 |
2.86e-07 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 54.14 E-value: 2.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 882 QLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELE 961
Cdd:COG4372 42 KLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQ 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 962 KFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLK-----LNITQLQQKLKATDNELHKERQKKQN 1036
Cdd:COG4372 122 KERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEqelqaLSEAEAEQALDELLKEANRNAEKEEE 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1037 MEALIKRFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEV 1116
Cdd:COG4372 202 LAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIA 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1117 HQAAYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSSPAVLRLNAQKENEKIIEMQ 1196
Cdd:COG4372 282 ALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSK 361
|
....*.
gi 2024426573 1197 LLEIQH 1202
Cdd:COG4372 362 GAEAGV 367
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
726-1039 |
4.78e-07 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 52.99 E-value: 4.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 726 ETFTQELESLKNKHQILQAEKDnqemQHQLQLSELmNKHAKEMRdlesdsnQKLLMENEKYQELQVDSQRMQEEYEKQLH 805
Cdd:COG1340 4 DELSSSLEELEEKIEELREEIE----ELKEKRDEL-NEELKELA-------EKRDELNAQVKELREEAQELREKRDELNE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 806 NLQESKNRTVEELtdyyeEKLNEKSLLLEEAEEDMRQQLQAH---EEIKKQIEEDEDR-EIQDIKIKYERWLIEEkesnl 881
Cdd:COG1340 72 KVKELKEERDELN-----EKLNELREELDELRKELAELNKAGgsiDKLRKEIERLEWRqQTEVLSPEEEKELVEK----- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 882 qlkgeIGVMNKRLNSLQKELKErNNDIEDMKLEqqnlqgiIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKnqele 961
Cdd:COG1340 142 -----IKELEKELEKAKKALEK-NEKLKELRAE-------LKELRKEAEEIHKKIKELAEEAQELHEEMIELYKE----- 203
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024426573 962 kfkfvldhrIEQFKKQIESrendikiMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEA 1039
Cdd:COG1340 204 ---------ADELRKEADE-------LHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL 265
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
786-1238 |
4.99e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.20 E-value: 4.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 786 YQELQVDSQRMQEEYEKQLHNLQESKNRTVEELTDYYeeKLN----EKSLLLEEAEEDmrQQLQAHEEIKKQIEEDEDRE 861
Cdd:TIGR00618 100 HRKTEQPEQLYLEQKKGRGRILAAKKSETEEVIHDLL--KLDyktfTRVVLLPQGEFA--QFLKAKSKEKKELLMNLFPL 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 862 IQdikikYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKleqQNLQGIIKSLEkdismlntniekrtn 941
Cdd:TIGR00618 176 DQ-----YTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERK---QVLEKELKHLR--------------- 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 942 TIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERE-----LEQLHKENTQLKLNITQL 1016
Cdd:TIGR00618 233 EALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRArkaapLAAHIKAVTQIEQQAQRI 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1017 QQKLKATDNELHKERQKKQNMEALikrfKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQR 1096
Cdd:TIGR00618 313 HTELQSKMRSRAKLLMKRAAHVKQ----QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQK 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1097 EYLERNLAALKKKVVK-DQEVHQAAytrimqenvSLIKEINDLRQELTVAHTQVHDLQSALKLtkKKQAIQDTAPSnETL 1175
Cdd:TIGR00618 389 TTLTQKLQSLCKELDIlQREQATID---------TRTSAFRDLQGQLAHAKKQQELQQRYAEL--CAAAITCTAQC-EKL 456
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 1176 SSPAVLRLnAQKENEKIIEMQLLEIQHLrdQVQEKGQGLEAQPLLYGMLPKLNLERSHKMHQH 1238
Cdd:TIGR00618 457 EKIHLQES-AQSLKEREQQLQTKEQIHL--QETRKKAVVLARLLELQEEPCPLCGSCIHPNPA 516
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
760-1167 |
5.94e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.00 E-value: 5.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 760 LMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEyEKQLHNLQESKNRTVEELtdyyeEKLNEKSLLLEEAEED 839
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEK-EEEYAELQEELEELEEEL-----EELEAELEELREELEK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 840 MRQQLQAHEEIKKQieEDEDREIQDIKIKYERWLIEEKESNlQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQqnlq 919
Cdd:COG4717 121 LEKLLQLLPLYQEL--EALEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQLSLATEEE---- 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 920 giIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKfkfvlDHRIEQFKKQIESRENDIKIM----------- 988
Cdd:COG4717 194 --LQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN-----ELEAAALEERLKEARLLLLIAaallallglgg 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 989 ---------------------------QKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALI 1041
Cdd:COG4717 267 sllsliltiagvlflvlgllallflllAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1042 KRFKMDLHNCVGFIQDYK--KLKAGIRELYTKY-VQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQ 1118
Cdd:COG4717 347 EELQELLREAEELEEELQleELEQEIAALLAEAgVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD 426
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 2024426573 1119 AAytRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQD 1167
Cdd:COG4717 427 EE--ELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAE 473
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
717-1020 |
6.77e-07 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 53.14 E-value: 6.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 717 CYEKIKELEetftqeleslknkhqiLQAEKDNQEMQHQlqlSELMNKHAKEmrdlesdsNQKLLMENEKYQELQvdsQRM 796
Cdd:pfam15742 88 CQQKIRELE----------------LEVLKQAQSIKSQ---NSLQEKLAQE--------KSRVADAEEKILELQ---QKL 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 797 qeeyeKQLHNLQESKNRTVEeltdyyEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEE 876
Cdd:pfam15742 138 -----EHAHKVCLTDTCILE------KKQLEERIKEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLE 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 877 KeSNLQLKGEIGVMNKRLNSLQKELKERNndiEDMKLeQQNLQGIIKSLEKDISMLNTNIEKRTNTIQE-----KEKHIY 951
Cdd:pfam15742 207 M-TNSQQQLRIQQQEAQLKQLENEKRKSD---EHLKS-NQELSEKLSSLQQEKEALQEELQQVLKQLDVhvrkyNEKHHH 281
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 952 DLKKknqeLEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKL 1020
Cdd:pfam15742 282 HKAK----LRRAKDRLVHEVEQRDERIKQLENEIGILQQQSEKEKAFQKQVTAQNEILLLEKRKLLEQL 346
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
722-1043 |
7.01e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 53.82 E-value: 7.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 722 KELEETFTQELESLKNKHQILQAEKDN--QEMQHQLQLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEE 799
Cdd:TIGR00618 562 KEQMQEIQQSFSILTQCDNRSKEDIPNlqNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQEL 641
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 800 YEKQLHNLQESKNRTVEE------LTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEdEDREIQDIKIKYERWL 873
Cdd:TIGR00618 642 ALKLTALHALQLTLTQERvrehalSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQT-LLRELETHIEEYDREF 720
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 874 IEEKESNLQLKGEIGVMNKRLNSLQKELKERnndiEDMKLEQQNLQGIIKSLEKDISMLntniekrtnTIQEKEKHIYDL 953
Cdd:TIGR00618 721 NEIENASSSLGSDLAAREDALNQSLKELMHQ----ARTVLKARTEAHFNNNEEVTAALQ---------TGAELSHLAAEI 787
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 954 KKKNQELEKfkfvLDHRIEQFKKQIES-RENDIKIMQKQIHEMERELEQLH---KENTQLKLNITQLQQKLKATDNELHK 1029
Cdd:TIGR00618 788 QFFNRLREE----DTHLLKTLEAEIGQeIPSDEDILNLQCETLVQEEEQFLsrlEEKSATLGEITHQLLKYEECSKQLAQ 863
|
330
....*....|....
gi 2024426573 1030 ERQKKQNMEALIKR 1043
Cdd:TIGR00618 864 LTQEQAKIIQLSDK 877
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
666-1044 |
7.74e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 53.64 E-value: 7.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 666 LKREKEFEYAEEVLIMKSDIE--EKSRTILDLQIRVKELQIendyQLRLKDMSCYEKIKELEETFTQELESLKNkhqILQ 743
Cdd:pfam01576 196 LKKEEKGRQELEKAKRKLEGEstDLQEQIAELQAQIAELRA----QLAKKEEELQAALARLEEETAQKNNALKK---IRE 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 744 AEKDNQEMQHQLQLSELM-NKHAKEMRDLESD----------------SNQKLLMENEkyQELQVDSQRMQEE---YEKQ 803
Cdd:pfam01576 269 LEAQISELQEDLESERAArNKAEKQRRDLGEElealkteledtldttaAQQELRSKRE--QEVTELKKALEEEtrsHEAQ 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 804 LHNLQESKNRTVEELTDYYEEKLNEKSLL------LEEAEEDMRQQLQAHEEIKKQIEEDEDR---EIQDIKIKY---ER 871
Cdd:pfam01576 347 LQEMRQKHTQALEELTEQLEQAKRNKANLekakqaLESENAELQAELRTLQQAKQDSEHKRKKlegQLQELQARLsesER 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 872 WLIEEKESNLQLKGEIGVMNKRLNS-------LQKELKERNNDIEDMKLEQQ-------NLQGIIKSLEKDISMLNTNIE 937
Cdd:pfam01576 427 QRAELAEKLSKLQSELESVSSLLNEaegknikLSKDVSSLESQLQDTQELLQeetrqklNLSTRLRQLEDERNSLQEQLE 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 938 KRTNTIQEKEKHIYDLKKKNQELEKfkfvldhRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQ 1017
Cdd:pfam01576 507 EEEEAKRNVERQLSTLQAQLSDMKK-------KLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQ 579
|
410 420
....*....|....*....|....*..
gi 2024426573 1018 QKLKATDNELHKERQKKQNMEALIKRF 1044
Cdd:pfam01576 580 QELDDLLVDLDHQRQLVSNLEKKQKKF 606
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
676-1157 |
8.20e-07 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 53.67 E-value: 8.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 676 EEVLIMKSDIEEKSRTILDLQIRVKELQIENDYQ---LRLKDmscyEKIKELeetftqeLESLKNKHQILQAEKDNQEMQ 752
Cdd:pfam10174 116 ENFRRLQSEHERQAKELFLLRKTLEEMELRIETQkqtLGARD----ESIKKL-------LEMLQSKGLPKKSGEEDWERT 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 753 HQLQLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMqeeyeKQLHNLQESKNRTVEELTDYYEEKLNEKSLL 832
Cdd:pfam10174 185 RRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKT-----KALQTVIEMKDTKISSLERNIRDLEDEVQML 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 833 LEEAEEDMRQqlqaHEEIKKQIEEDEDREiqdikiKYERWLIEekesnlQLKGEIGVMNKRLNSLQKELKERNNDIEDMK 912
Cdd:pfam10174 260 KTNGLLHTED----REEEIKQMEVYKSHS------KFMKNKID------QLKQELSKKESELLALQTKLETLTNQNSDCK 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 913 LEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQI 992
Cdd:pfam10174 324 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKI 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 993 HEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDL-HNCVGFIQDYKKLKAGIRELYTK 1071
Cdd:pfam10174 404 ENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQReREDRERLEELESLKKENKDLKEK 483
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1072 Y-VQQLEMVEMEEVDTDLQQEYMRQR----------EYLERNLAALKKKVVKDQEVHQAAYTRIMQENVS---------L 1131
Cdd:pfam10174 484 VsALQPELTEKESSLIDLKEHASSLAssglkkdsklKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNpeindrirlL 563
|
490 500
....*....|....*....|....*.
gi 2024426573 1132 IKEINDLRQELTVAHTQVHDLQSALK 1157
Cdd:pfam10174 564 EQEVARYKEESGKAQAEVERLLGILR 589
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
667-979 |
1.00e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 53.20 E-value: 1.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 667 KREKEFEYAEEVLImKSDIEEKSRtilDLQIRVKELQIENDYQLRL-KDMSCYEKIKELEETFTQELESLKNKHQILQAE 745
Cdd:pfam17380 288 QQQEKFEKMEQERL-RQEKEEKAR---EVERRRKLEEAEKARQAEMdRQAAIYAEQERMAMERERELERIRQEERKRELE 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 746 KDNQ-----EMQHQLQLSEL-MNKHAKEMR---DLESDSNQKLLmENEKYQELQVDSQRMqEEYEKQLHNLQESKNRTVE 816
Cdd:pfam17380 364 RIRQeeiamEISRMRELERLqMERQQKNERvrqELEAARKVKIL-EEERQRKIQQQKVEM-EQIRAEQEEARQREVRRLE 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 817 ELTDYYEEKLNEKSLLLEEAEEDMRQQlQAHEEIKKQIEEDEDREIQdiKIKYERWLIEEKESNLQLKGEIGVMNKRlNS 896
Cdd:pfam17380 442 EERAREMERVRLEEQERQQQVERLRQQ-EEERKRKKLELEKEKRDRK--RAEEQRRKILEKELEERKQAMIEEERKR-KL 517
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 897 LQKELKERNNDIedmkLEQQNLQGIIKSLEKDISMlntniEKRTNtIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKK 976
Cdd:pfam17380 518 LEKEMEERQKAI----YEEERRREAEEERRKQQEM-----EERRR-IQEQMRKATEERSRLEAMEREREMMRQIVESEKA 587
|
...
gi 2024426573 977 QIE 979
Cdd:pfam17380 588 RAE 590
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
666-919 |
1.07e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.40 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 666 LKREKEfEYAEEVLIMKSDIEEKSRTILDLQIRVKELQiENDYQLRLKDMSCYEKIKELEET----------FTQELESL 735
Cdd:COG1196 251 LEAELE-ELEAELAELEAELEELRLELEELELELEEAQ-AEEYELLAELARLEQDIARLEERrreleerleeLEEELAEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 736 KNKHQILQAEKDNQEMQHQL---QLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQE--EYEKQLHNLQES 810
Cdd:COG1196 329 EEELEELEEELEELEEELEEaeeELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAaaELAAQLEELEEA 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 811 KNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEEKESNL-QLKGEIGV 889
Cdd:COG1196 409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALaELLEELAE 488
|
250 260 270
....*....|....*....|....*....|
gi 2024426573 890 MNKRLNSLQKELKERNNDIEDMKLEQQNLQ 919
Cdd:COG1196 489 AAARLLLLLEAEADYEGFLEGVKAALLLAG 518
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
968-1191 |
1.18e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 52.14 E-value: 1.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 968 DHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKEntqlklnITQLQQKLKATDNELHKERQKKQNMEALIKrfkmd 1047
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEE-------YNELQAELEALQAEIDKLQAEIAEAEAEIE----- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1048 lhncvgfiQDYKKLKAGIRELYTK------------------YVQQLEMVE-MEEVDTDLQQEYMRQREYLERNLAALKK 1108
Cdd:COG3883 83 --------ERREELGERARALYRSggsvsyldvllgsesfsdFLDRLSALSkIADADADLLEELKADKAELEAKKAELEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1109 KvVKDQEVHQAAYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSSPAVLRLNAQKE 1188
Cdd:COG3883 155 K-LAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233
|
...
gi 2024426573 1189 NEK 1191
Cdd:COG3883 234 AAA 236
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
668-1045 |
1.85e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.08 E-value: 1.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 668 REKEFEYAEEVlimkSDIEEKSRTILDLQIRVKELQIE-NDYQLRLKDMSCYEKIKELEE---TFTQELESLKNKHQILQ 743
Cdd:COG4717 84 EEKEEEYAELQ----EELEELEEELEELEAELEELREElEKLEKLLQLLPLYQELEALEAelaELPERLEELEERLEELR 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 744 aEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEK---QLHNLQESKNRTVEELTD 820
Cdd:COG4717 160 -ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEaqeELEELEEELEQLENELEA 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 821 YYEEKLNEK------------------------------------SLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQD 864
Cdd:COG4717 239 AALEERLKEarlllliaaallallglggsllsliltiagvlflvlGLLALLFLLLAREKASLGKEAEELQALPALEELEE 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 865 IKIKyeRWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLE------QQNLQGIIKSLEKDISMLNTNIEK 938
Cdd:COG4717 319 EELE--ELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEeleqeiAALLAEAGVEDEEELRAALEQAEE 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 939 RTNTIQEKEKHIYDLKKKNQELEKFKFVLD-----HRIEQFKKQIESRENDIKIMQKQIHEMERELEQLhkENTQLKLNI 1013
Cdd:COG4717 397 YQELKEELEELEEQLEELLGELEELLEALDeeeleEELEELEEELEELEEELEELREELAELEAELEQL--EEDGELAEL 474
|
410 420 430
....*....|....*....|....*....|....*.
gi 2024426573 1014 TQLQQKLKATDNELHKERQK----KQNMEALIKRFK 1045
Cdd:COG4717 475 LQELEELKAELRELAEEWAAlklaLELLEEAREEYR 510
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
713-1210 |
2.08e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 52.36 E-value: 2.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 713 KDMSCYEKIKELEETFTQELESL---------------KNKHQILQAEKDNQEMQHQLQLSELMNKHAKemRDLESDSNQ 777
Cdd:TIGR00606 543 DKMDKDEQIRKIKSRHSDELTSLlgyfpnkkqledwlhSKSKEINQTRDRLAKLNKELASLEQNKNHIN--NELESKEEQ 620
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 778 KLLMENEKY-----QELQVDSQRMQEEYEKQLHNLQESKNRT------VEELTDY--------------------YEEKL 826
Cdd:TIGR00606 621 LSSYEDKLFdvcgsQDEESDLERLKEEIEKSSKQRAMLAGATavysqfITQLTDEnqsccpvcqrvfqteaelqeFISDL 700
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 827 NEKSLL----LEEAEEDMRQQLQAHEEI---------KKQIEEDEDREIQDIKIKYERWLIEEKESNLQLKGEIGVMNKR 893
Cdd:TIGR00606 701 QSKLRLapdkLKSTESELKKKEKRRDEMlglapgrqsIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE 780
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 894 LNS-------------LQKELKERNNDIE---------DMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIY 951
Cdd:TIGR00606 781 EESakvcltdvtimerFQMELKDVERKIAqqaaklqgsDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQ 860
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 952 DLKKKNQELEKFKFVLD---HRIEQFKKQIESrendikiMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELH 1028
Cdd:TIGR00606 861 HLKSKTNELKSEKLQIGtnlQRRQQFEEQLVE-------LSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKE 933
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1029 KERQKKQNMEALIKRfkmDLHNCVGFIQDYKKLkagIRELYTKYVQQLEmVEMEEVDTDLqQEYMRQREYLERNLAALKK 1108
Cdd:TIGR00606 934 TSNKKAQDKVNDIKE---KVKNIHGYMKDIENK---IQDGKDDYLKQKE-TELNTVNAQL-EECEKHQEKINEDMRLMRQ 1005
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1109 KVVKdqevhQAAYTRIMQENVSLIK---EINDLRQELTVAHTQVHDLQsalkLTKKKQAIQDTAPSNETLSSPAVLRLNA 1185
Cdd:TIGR00606 1006 DIDT-----QKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQ----VLQMKQEHQKLEENIDLIKRNHVLALGR 1076
|
570 580
....*....|....*....|....*
gi 2024426573 1186 QKENEKiiemqllEIQHLRDQVQEK 1210
Cdd:TIGR00606 1077 QKGYEK-------EIKHFKKELREP 1094
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
681-1046 |
2.37e-06 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 51.61 E-value: 2.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 681 MKSDIEEKSRTILDLQIRVKELQIENDYQLRLKD-----MSCYEKIKELE---ETFTQELESLKN-KHQILQAEKDNQE- 750
Cdd:pfam05622 85 YRIKCEELEKEVLELQHRNEELTSLAEEAQALKDemdilRESSDKVKKLEatvETYKKKLEDLGDlRRQVKLLEERNAEy 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 751 MQHQLQLSELMNKHAKEMRDLESDSNQ------KLLMENEKYQELQVDSQRMQEEYEKqlhnLQESKNRTVEELTDyyee 824
Cdd:pfam05622 165 MQRTLQLEEELKKANALRGQLETYKRQvqelhgKLSEESKKADKLEFEYKKLEEKLEA----LQKEKERLIIERDT---- 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 825 klneksllLEEAEEDMR-QQLQAHEEIKKQIEEDED--------REIQDIKIKyERWLIEEKESNLQLKGEIGVMNKRLN 895
Cdd:pfam05622 237 --------LRETNEELRcAQLQQAELSQADALLSPSsdpgdnlaAEIMPAEIR-EKLIRLQHENKMLRLGQEGSYRERLT 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 896 SLQKELKERNNDIEdmKLEQQNlqgiiKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKfkfvldhrieqfk 975
Cdd:pfam05622 308 ELQQLLEDANRRKN--ELETQN-----RLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEE------------- 367
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 976 kqiesrendikimqkqihemerELEQLHKENTQLK--------LNITQLQQKLKATDNELHKERQKKQNMEALIKRFKM 1046
Cdd:pfam05622 368 ----------------------HLEKLHEAQSELQkkkeqieeLEPKQDSNLAQKIDELQEALRKKDEDMKAMEERYKK 424
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
797-1035 |
2.46e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 51.37 E-value: 2.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 797 QEEYEKQLHNLQESKNRTVEELTDYYEEklneksllLEEAEEDMRQQLQAHEEIKKQIEEDEDReiqdikikyerwlIEE 876
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAELDALQAE--------LEELNEEYNELQAELEALQAEIDKLQAE-------------IAE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 877 KESNLQLKGEIgvMNKRLNSLQKElkERNNDIEDMKLEQQNLQGIIKSLekdiSMLNTNIEKRTNTIQEkekhiydLKKK 956
Cdd:COG3883 77 AEAEIEERREE--LGERARALYRS--GGSVSYLDVLLGSESFSDFLDRL----SALSKIADADADLLEE-------LKAD 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 957 NQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQ 1035
Cdd:COG3883 142 KAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
701-1045 |
2.60e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 52.10 E-value: 2.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 701 ELQIENDYQLRLKdmscyEKIKELEETFTQELESLKNkhqilQAEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQKLL 780
Cdd:pfam01576 707 ELQATEDAKLRLE-----VNMQALKAQFERDLQARDE-----QGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLE 776
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 781 MENEKYqELQVDS-QRMQEEYEKQLHNLQ---ESKNRTVEELTDYYEE-----KLNEKSLLLEEAEE-DMRQQLQAHEEI 850
Cdd:pfam01576 777 LDLKEL-EAQIDAaNKGREEAVKQLKKLQaqmKDLQRELEEARASRDEilaqsKESEKKLKNLEAELlQLQEDLAASERA 855
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 851 KKQIEEDEDrEIQDikikyerWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDIS 930
Cdd:pfam01576 856 RRQAQQERD-ELAD-------EIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELA 927
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 931 MLNTNIEKRTNTIQEKEKHIYDLKKKNQELEkfkfvldhrieqfkKQIESR-ENDIKIMQKQIHEMERELEQLHKENTQL 1009
Cdd:pfam01576 928 AERSTSQKSESARQQLERQNKELKAKLQEME--------------GTVKSKfKSSIAALEAKIAQLEEQLEQESRERQAA 993
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 2024426573 1010 KLNITQLQQKLKATDNELHKER----QKKQNMEALIKRFK 1045
Cdd:pfam01576 994 NKLVRRTEKKLKEVLLQVEDERrhadQYKDQAEKGNSRMK 1033
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
910-1097 |
2.61e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.92 E-value: 2.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 910 DMKLEQqnLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENdikimQ 989
Cdd:COG1579 16 DSELDR--LEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-----N 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 990 KQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKmdlhncvgfiQDYKKLKAGIRELY 1069
Cdd:COG1579 89 KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKK----------AELDEELAELEAEL 158
|
170 180
....*....|....*....|....*...
gi 2024426573 1070 TKYVQQLEMVEmEEVDTDLQQEYMRQRE 1097
Cdd:COG1579 159 EELEAEREELA-AKIPPELLALYERIRK 185
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
719-1030 |
4.08e-06 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 50.99 E-value: 4.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEETFTQ--ELES----LKNKHQILQAEKDNQEMQHQLQ-----LSELMNKHAKEMRDLEsDSNQKLLMENEKYQ 787
Cdd:PRK04778 172 KQLENLEEEFSQfvELTEsgdyVEAREILDQLEEELAALEQIMEeipelLKELQTELPDQLQELK-AGYRELVEEGYHLD 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 788 ELQVDsqrmqeeyeKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKi 867
Cdd:PRK04778 251 HLDIE---------KEIQDLKEQIDENLALLEELDLDEAEEKNEEIQERIDQLYDILEREVKARKYVEKNSDTLPDFLE- 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 868 kyerwliEEKESNLQLKGEIGVMNK--RLN--------SLQKELK--ERNNDIEDMKLEQQN-----LQGIIKSLEKDIS 930
Cdd:PRK04778 321 -------HAKEQNKELKEEIDRVKQsyTLNeselesvrQLEKQLEslEKQYDEITERIAEQEiayseLQEELEEILKQLE 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 931 MLNTNIEKRTNTIQEKEKhiyDLKKKNQELEKFKFvldhRIEQFKKQIESRE-----NDIKIMQKqihEMERELEQLHKE 1005
Cdd:PRK04778 394 EIEKEQEKLSEMLQGLRK---DELEAREKLERYRN----KLHEIKRYLEKSNlpglpEDYLEMFF---EVSDEIEALAEE 463
|
330 340
....*....|....*....|....*...
gi 2024426573 1006 NTQLKLNITQLQQKL-KATD--NELHKE 1030
Cdd:PRK04778 464 LEEKPINMEAVNRLLeEATEdvETLEEE 491
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
661-865 |
4.13e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.93 E-value: 4.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 661 KKGKILKREKEFEYAEEVLIMKSDIEeksrtildlqirvKELQIENdyqlrlkdmscyEKIKELEETFTQELESLKNKHQ 740
Cdd:PRK12704 49 KEAEAIKKEALLEAKEEIHKLRNEFE-------------KELRERR------------NELQKLEKRLLQKEENLDRKLE 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 741 ILqaEKDNQEMQHQLQLSElmnkhakemrdlesdsnqkllmenEKYQELQVDSQRMQEEYEKQLHNLQESKNRTVEEltd 820
Cdd:PRK12704 104 LL--EKREEELEKKEKELE------------------------QKQQELEKKEEELEELIEEQLQELERISGLTAEE--- 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2024426573 821 yyeeklnEKSLLLEEAEEDMRQQLQAH-EEIKKQIEEDEDREIQDI 865
Cdd:PRK12704 155 -------AKEILLEKVEEEARHEAAVLiKEIEEEAKEEADKKAKEI 193
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
660-1208 |
4.58e-06 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 51.23 E-value: 4.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 660 SKKGKILKREKEFE---YAEEVLIMKSDIEEKSRTILDLQIRVKELQIENDYQLRLkDMSCYEKIKELEETFTQELEsLK 736
Cdd:COG5022 849 QKFGRSLKAKKRFSllkKETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLEL-ESEIIELKKSLSSDLIENLE-FK 926
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 737 NKHqILQAEKDNQEMQHQLQLS------ELMNKHAKEMRDLEsDSNQKLLMENEKYQELQVDSQRMQEEyekqLHNLQES 810
Cdd:COG5022 927 TEL-IARLKKLLNNIDLEEGPSieyvklPELNKLHEVESKLK-ETSEEYEDLLKKSTILVREGNKANSE----LKNFKKE 1000
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 811 KNRTVEELTDYYEEK--LNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYER----WLIEEKESNLQLK 884
Cdd:COG5022 1001 LAELSKQYGALQESTkqLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQarykALKLRRENSLLDD 1080
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 885 GEIGVMN------KRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDIS----MLNTNIEKRTNTIQEKEK------ 948
Cdd:COG5022 1081 KQLYQLEstenllKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISkflsQLVNTLEPVFQKLSVLQLeldglf 1160
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 949 ---------HIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEmERELEQLHKENTQLKLNITQLQQK 1019
Cdd:COG5022 1161 weanlealpSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALFSKIFS-GWPRGDKLKKLISEGWVPTEYSTS 1239
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1020 LKATDN-ELHKERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIRELYT-------------------KYVQQLEMV 1079
Cdd:COG5022 1240 LKGFNNlNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQyinvglfnalrtkasslrwKSATEVNYN 1319
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1080 EMEEVDTDLQQEYMRQREYLERNLAALK-KKVVKDqevhqaaytrimqeNVSLIKEINDLRQELTVAHTQ--VHDLQSAL 1156
Cdd:COG5022 1320 SEELDDWCREFEISDVDEELEELIQAVKvLQLLKD--------------DLNKLDELLDACYSLNPAEIQnlKSRYDPAD 1385
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 1157 KLTKKKQAIQDTAPSNETLSSPAVLRLNAQKENEKIIEMQLLEIQHLRDQVQ 1208
Cdd:COG5022 1386 KENNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFSEEKSLISLDRN 1437
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
841-1018 |
5.92e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.55 E-value: 5.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 841 RQQLQAHEEIKKQIEEDEDREIQDIKikyERWLIEEKESNLQLKGEigvmnkrlnsLQKELKERNNDIEdmKLEQQNLQg 920
Cdd:PRK12704 30 EAKIKEAEEEAKRILEEAKKEAEAIK---KEALLEAKEEIHKLRNE----------FEKELRERRNELQ--KLEKRLLQ- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 921 iikslekdismlntniekrtntiqeKEKHiydLKKKNQELEKfkfvLDHRIEQFKKQIESRENDIKimqkqihEMERELE 1000
Cdd:PRK12704 94 -------------------------KEEN---LDRKLELLEK----REEELEKKEKELEQKQQELE-------KKEEELE 134
|
170
....*....|....*...
gi 2024426573 1001 QLHKENTQLKLNITQLQQ 1018
Cdd:PRK12704 135 ELIEEQLQELERISGLTA 152
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
897-1192 |
7.46e-06 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 49.90 E-value: 7.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 897 LQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKK 976
Cdd:COG4372 29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 977 QIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQ 1056
Cdd:COG4372 109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1057 DYKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEIN 1136
Cdd:COG4372 189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024426573 1137 DLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSSPAVLRLNAQKENEKI 1192
Cdd:COG4372 269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLEL 324
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
684-1140 |
9.43e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 50.29 E-value: 9.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 684 DIEEKSRTILDLQIRVKELQ--------IENDYQLRLKDMSCYEK-IKELEETFT---QELESLKNKHQILQAEKD--NQ 749
Cdd:PRK01156 160 EINSLERNYDKLKDVIDMLRaeisnidyLEEKLKSSNLELENIKKqIADDEKSHSitlKEIERLSIEYNNAMDDYNnlKS 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 750 EMQHQLQLSELMNKHAKEMRDLESDSnQKLLMENEKYQELQVDSQRMQ---------------------EEYEKQLHNLQ 808
Cdd:PRK01156 240 ALNELSSLEDMKNRYESEIKTAESDL-SMELEKNNYYKELEERHMKIIndpvyknrnyindyfkykndiENKKQILSNID 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 809 ------ESKNRTVEELTDYYEEKLNEKS---------LLLEEAEEDMRQQLQAHEEIKKQIEEdEDREIQDIKIKYERWL 873
Cdd:PRK01156 319 aeinkyHAIIKKLSVLQKDYNDYIKKKSryddlnnqiLELEGYEMDYNSYLKSIESLKKKIEE-YSKNIERMSAFISEIL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 874 -------------IEEKESNL-QLKGEIGVMNKRLNSLQKELKERNNDIEDMK-----------LEQQNLQGIIKSLEKD 928
Cdd:PRK01156 398 kiqeidpdaikkeLNEINVKLqDISSKVSSLNQRIRALRENLDELSRNMEMLNgqsvcpvcgttLGEEKSNHIINHYNEK 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 929 ISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKF-----------VLDHRIEQFK-------------KQIESREN- 983
Cdd:PRK01156 478 KSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEInksineynkieSARADLEDIKikinelkdkhdkyEEIKNRYKs 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 984 -----------------------DIKIMQKQIHEMERELEQLHKENTQLKLNI----TQLQQKLKATDNELHKERQKKQN 1036
Cdd:PRK01156 558 lkledldskrtswlnalavisliDIETNRSRSNEIKKQLNDLESRLQEIEIGFpddkSYIDKSIREIENEANNLNNKYNE 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1037 MEALikrfKMDLHNCVGFIQDYKKLKAGIRELYTKyvQQLEMVEMEEVDTDLQQeYMRQREYLERNLAALKKKV------ 1110
Cdd:PRK01156 638 IQEN----KILIEKLRGKIDNYKKQIAEIDSIIPD--LKEITSRINDIEDNLKK-SRKALDDAKANRARLESTIeilrtr 710
|
570 580 590
....*....|....*....|....*....|
gi 2024426573 1111 VKDQEVHQAAYTRIMQENVSLIKEINDLRQ 1140
Cdd:PRK01156 711 INELSDRINDINETLESMKKIKKAIGDLKR 740
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
842-1021 |
1.13e-05 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 49.67 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 842 QQLQAHEEIKKQIEEDEDREIQDIK--IKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDmKLEQQNLQ 919
Cdd:pfam13166 283 EFQNRLQKLIEKVESAISSLLAQLPavSDLASLLSAFELDVEDIESEAEVLNSQLDGLRRALEAKRKDPFK-SIELDSVD 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 920 GIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKnqeLEKfkfvldHRIEQFKKQIESRENDIKIMQKQIHEMEREL 999
Cdd:pfam13166 362 AKIESINDLVASINELIAKHNEITDNFEEEKNKAKKK---LRL------HLVEEFKSEIDEYKDKYAGLEKAINSLEKEI 432
|
170 180
....*....|....*....|..
gi 2024426573 1000 EQLHKENTQLKLNITQLQQKLK 1021
Cdd:pfam13166 433 KNLEAEIKKLREEIKELEAQLR 454
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
816-1019 |
1.25e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.91 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 816 EELTDYYE--EKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEEKEsnlqLKGEIGVMNKR 893
Cdd:COG4913 235 DDLERAHEalEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEE----LRAELARLEAE 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 894 LNSLQKELKERNNDIEDMKLEQQNLQGI-IKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKfkfVLDHRIE 972
Cdd:COG4913 311 LERLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAE---EFAALRA 387
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2024426573 973 QFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQK 1019
Cdd:COG4913 388 EAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
661-1042 |
1.30e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 1.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 661 KKGKILKREKEFEYAEEvliMKSDIEEKsRTILDLQIRVKELQIENDYQLRLKDMSCYEKIKELEETFTQELESLKNKHQ 740
Cdd:PTZ00121 1406 KADELKKAAAAKKKADE---AKKKAEEK-KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE 1481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 741 ILQAEKDNQEMQHQLQLSELMNKHAKEMRDLESdsnQKLLMENEKYQEL-QVDSQRMQEEYEKQLHNLQESKNRTVEELT 819
Cdd:PTZ00121 1482 AKKADEAKKKAEEAKKKADEAKKAAEAKKKADE---AKKAEEAKKADEAkKAEEAKKADEAKKAEEKKKADELKKAEELK 1558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 820 DYYEEKLNEKSlllEEAEEDMRQQLQAHEEIKK----QIEEDEDREIQDIKIKYE--RWLIEEKESNLQLKGEIGVmNKR 893
Cdd:PTZ00121 1559 KAEEKKKAEEA---KKAEEDKNMALRKAEEAKKaeeaRIEEVMKLYEEEKKMKAEeaKKAEEAKIKAEELKKAEEE-KKK 1634
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 894 LNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKfkfvldhrIEQ 973
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK--------AEE 1706
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 974 FKKQIEsrendikimqkqihEMERELEQLHKENTQLKLNITQLQQKL---KATDNELHKERQKKQNMEALIK 1042
Cdd:PTZ00121 1707 LKKKEA--------------EEKKKAEELKKAEEENKIKAEEAKKEAeedKKKAEEAKKDEEEKKKIAHLKK 1764
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
833-1115 |
1.49e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 48.75 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 833 LEEAEEDMRQQLQAHEEIKKQIEEdEDREIQDIKIKyerwlIEEKESNLQ-LKGEIGVMNKRLNSLQKELKERNNDIEDM 911
Cdd:COG4372 47 LEQLREELEQAREELEQLEEELEQ-ARSELEQLEEE-----LEELNEQLQaAQAELAQAQEELESLQEEAEELQEELEEL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 912 KLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKF-----KFVLDHRIEQFKKQIESRENDIK 986
Cdd:COG4372 121 QKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQElqalsEAEAEQALDELLKEANRNAEKEE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 987 IMQKQI---HEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKA 1063
Cdd:COG4372 201 ELAEAEkliESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEI 280
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 1064 GIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQE 1115
Cdd:COG4372 281 AALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELAL 332
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
883-1082 |
1.59e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 49.24 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 883 LKGEIGVMNKRLNSLQKELKERNNDIEDM----KLEQQNLQGIIKSL---EKDISMLNTNIEKR-TNTIQEKEKHIYDLK 954
Cdd:PHA02562 179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQrkknGENIARKQNKYDELveeAKTIKAEIEELTDElLNLVMDIEDPSAALN 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 955 KKNQELEKFKfvldHRIEQFKK----------------QIESRENDIKIMQKQIHEMERELEQL--HKENTQLKLN-ITQ 1015
Cdd:PHA02562 259 KLNTAAAKIK----SKIEQFQKvikmyekggvcptctqQISEGPDRITKIKDKLKELQHSLEKLdtAIDELEEIMDeFNE 334
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024426573 1016 LQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMVEME 1082
Cdd:PHA02562 335 QSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKE 401
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
805-1033 |
1.64e-05 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 48.27 E-value: 1.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 805 HNLQESKNRTVEELTDYYEEKLNEK---SLLLEEAEEDmrQQLQAHEEIKKQIEED------EDREIQDIKIKYERWLIE 875
Cdd:pfam15905 56 VKSLELKKKSQKNLKESKDQKELEKeirALVQERGEQD--KRLQALEEELEKVEAKlnaavrEKTSLSASVASLEKQLLE 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 876 EKESN--LQLKGEIGVMNKRLNSLQKELKERNNDI-----------EDMKLEQQ--------------NLQGIIKSLEKD 928
Cdd:pfam15905 134 LTRVNelLKAKFSEDGTQKKMSSLSMELMKLRNKLeakmkevmakqEGMEGKLQvtqknlehskgkvaQLEEKLVSTEKE 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 929 ISMLNTNIEKRTNTIQE-------KEKHIYD-------LKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHE 994
Cdd:pfam15905 214 KIEEKSETEKLLEYITElscvseqVEKYKLDiaqleelLKEKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEKEE 293
|
250 260 270
....*....|....*....|....*....|....*....
gi 2024426573 995 MERELEQlhKENTqLKLNITQLQQKLKATDNELHKERQK 1033
Cdd:pfam15905 294 LLREYEE--KEQT-LNAELEELKEKLTLEEQEHQKLQQK 329
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
730-911 |
2.03e-05 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 47.06 E-value: 2.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 730 QELESLKNKHQILQAEkdnqeMQHQLQLSELMNKHAKEMRDLESDSNQKLlmeNEKYQELQVDSQRMQEEYEKQLHNLQE 809
Cdd:cd00176 33 ESVEALLKKHEALEAE-----LAAHEERVEALNELGEQLIEEGHPDAEEI---QERLEELNQRWEELRELAEERRQRLEE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 810 S-----KNRTVEELTDYYEEKLNE-KSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDReIQDIKIKYERwLIEEK--ESNL 881
Cdd:cd00176 105 AldlqqFFRDADDLEQWLEEKEAAlASEDLGKDLESVEELLKKHKELEEELEAHEPR-LKSLNELAEE-LLEEGhpDADE 182
|
170 180 190
....*....|....*....|....*....|
gi 2024426573 882 QLKGEIGVMNKRLNSLQKELKERNNDIEDM 911
Cdd:cd00176 183 EIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
672-1212 |
2.83e-05 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 48.67 E-value: 2.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 672 FEYAEEVLIMKSDIEEKSRTILDLQIRVKELqiendyqlrlkdmscYEKIKELEEtFTQELESLKNKHQILQAEKDNqem 751
Cdd:PTZ00440 1902 YKSSLQILKYSDDIDKKQRDCNKLVEDGNEI---------------YLKSTAINE-LKNMINSVKNKESAISNKIDN--- 1962
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 752 qhqlqlseLMNKHAKEMRDLESDSNQKLLMENEKYQELQvdsqrmqeeyeKQLHNLQESKNRTVEEL-TDYYEEKLNEKS 830
Cdd:PTZ00440 1963 --------VSNKLSELNKITCNDESYDEILEKEEYEELK-----------DLRNSFNQEKAETLNNLkLNKIKEDFNSYK 2023
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 831 LLLEEAEEDMrQQLQAHEEIKKQIeEDEDREIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKER-----N 905
Cdd:PTZ00440 2024 NLLDELEKSV-KTLKASENIKKIV-ENKKTSIDAINTNIEDIEKEIESINPSLDELLKKGHKIEISRYTSIIDNvqtkiS 2101
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 906 NDIEDMKLEQQNLQGIIKSLE-------KDISMLNTNIEKRT------NTIQEKEKHIYDLKKKNQELEKFkfvldhrIE 972
Cdd:PTZ00440 2102 NDSKNINDIEKKAQIYLAYIKnnynsikKDISTLNEYFDEKQvsnyilTNIDKANKLSSELSEAVTNSEEI-------IE 2174
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 973 QFKKQI-ESREND----IKIMQKQIHEMEREL--EQLHKENTQLKLNITQLQQKLKATD-----NELHKERQKKQNMEAL 1040
Cdd:PTZ00440 2175 NIKKEIiEINENTemntLENTADKLKELYENLkkKKNIINNIYKKINFIKLQEIENSSEkyndiSKLFNNVVETQKKKLL 2254
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1041 IKRFKMD---------------------LHNCVGFIQDYKKLKAGIRELYTkyVQQLEMVEMEEVDTDLQQEY--MRQRE 1097
Cdd:PTZ00440 2255 DNKNKINnikdkindkekelinvdssftLESIKTFNEIYDDIKSNIGDLYK--LEDTNNDELKKVKLYIENIThlLNRIN 2332
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1098 YLERNLaalkkKVVKDQEVHQAAYTRIMQENVSLIKE----INDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNE 1173
Cdd:PTZ00440 2333 TLINDL-----DNYQDENYGKDKNIELNNENNSYIIKtkekINNLKEEFSKLLKNIKRNNTLCNNNNIKDFISNIGKSVE 2407
|
570 580 590
....*....|....*....|....*....|....*....
gi 2024426573 1174 TLSSPAVLRLnAQKENEKIIEMQLLEIQHLRDQVQEKGQ 1212
Cdd:PTZ00440 2408 TIKQRFSSNL-PEKEKLHQIEENLNEIKNIMNETKRISN 2445
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
719-1210 |
3.07e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.60 E-value: 3.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEETFTQELESLKNKhqilqAEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQ--VDSQRM 796
Cdd:PTZ00121 1318 DEAKKKAEEAKKKADAAKKK-----AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKkkAEEKKK 1392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 797 QEEYEKQlhnlQESKNRTVEELTDYYEEK-----LNEKSLLLEEAEEDMRQQLQAH--EEIKKQIEE-----------DE 858
Cdd:PTZ00121 1393 ADEAKKK----AEEDKKKADELKKAAAAKkkadeAKKKAEEKKKADEAKKKAEEAKkaDEAKKKAEEakkaeeakkkaEE 1468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 859 DREIQDIKIKyerwlIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDismlntniEK 938
Cdd:PTZ00121 1469 AKKADEAKKK-----AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA--------KK 1535
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 939 RTNTIQEKEKHIYDLKKKNQELEKFKFVldHRIEQFKKQIESRENDIKIMQ--KQIHEME-RELEQLHKENTQLKLNITQ 1015
Cdd:PTZ00121 1536 ADEAKKAEEKKKADELKKAEELKKAEEK--KKAEEAKKAEEDKNMALRKAEeaKKAEEARiEEVMKLYEEEKKMKAEEAK 1613
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1016 LQQKLKATDNELHKERQKKQNMEALIKRFKmdlhncvgfiQDYKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQ 1095
Cdd:PTZ00121 1614 KAEEAKIKAEELKKAEEEKKKVEQLKKKEA----------EEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA 1683
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1096 REYLERNLAALKKKVVKDQEVHQaaytrIMQENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKK--QAIQDTAPSNE 1173
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEE-----LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKaeEAKKDEEEKKK 1758
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 2024426573 1174 TLSSPAVLRLNAQ---KENEKIIEMQLLEIQHLRDQVQEK 1210
Cdd:PTZ00121 1759 IAHLKKEEEKKAEeirKEKEAVIEEELDEEDEKRRMEVDK 1798
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
738-1039 |
4.01e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.58 E-value: 4.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 738 KHQILQaekdNQEMQHQLQLSELMNKHAKEMRDLESDSNQKLLMENE---KYQELQVDSQRMQEEYeKQLHNLQESKNRT 814
Cdd:pfam07888 28 RAELLQ----NRLEECLQERAELLQAQEAANRQREKEKERYKRDREQwerQRRELESRVAELKEEL-RQSREKHEELEEK 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 815 VEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYE-----RWLIEEKESNLQLKGEIGV 889
Cdd:pfam07888 103 YKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERakkagAQRKEEEAERKQLQAKLQQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 890 MNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIkslekdismlnTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDH 969
Cdd:pfam07888 183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTI-----------TTLTQKLTTAHRKEAENEALLEELRSLQERLNASER 251
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024426573 970 RIEQFKKQIESrendikiMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQK-KQNMEA 1039
Cdd:pfam07888 252 KVEGLGEELSS-------MAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETlQQSAEA 315
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
499-668 |
4.48e-05 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 47.21 E-value: 4.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 499 LKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWNLSTGKREMECVLTSCIYSSIALHSDSKIIFAVGSDQTLK--EISESS 576
Cdd:COG2319 32 LLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRlwDLATGL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 577 VHHEVPAFDVVYTAVAVSHSGDMVFVGTSLGTVRsmKYPLPLCRDFNEYQAHAGAITKMSVTNDDLFLLTASEDGSIFFW 656
Cdd:COG2319 112 LLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVR--LWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLW 189
|
170
....*....|..
gi 2024426573 657 KVCSkkGKILKR 668
Cdd:COG2319 190 DLAT--GKLLRT 199
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
898-1039 |
5.07e-05 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 47.75 E-value: 5.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 898 QKELKERNNDIEDMKLEQQNLQGiikslekDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKkq 977
Cdd:pfam05911 680 TEENKRLKEEFEQLKSEKENLEV-------ELASCTENLESTKSQLQESEQLIAELRSELASLKESNSLAETQLKCMA-- 750
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 978 iesrendikimqkqihEMERELEQLHKEntqLKLNITQLQQKLKATDNELHKERQKKQNMEA 1039
Cdd:pfam05911 751 ----------------ESYEDLETRLTE---LEAELNELRQKFEALEVELEEEKNCHEELEA 793
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
807-1087 |
5.89e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 47.23 E-value: 5.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 807 LQESKNRTVEEL--------TDYYEEKLNEKsllLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERW--LIEE 876
Cdd:PRK05771 14 LKSYKDEVLEALhelgvvhiEDLKEELSNER---LRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLeeLIKD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 877 KESNLqlkgeigvmnkrlNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEK------DISMLNT--NIEKRTNTIQE--K 946
Cdd:PRK05771 91 VEEEL-------------EKIEKEIKELEEEISELENEIKELEQEIERLEPwgnfdlDLSLLLGfkYVSVFVGTVPEdkL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 947 EKHIYDLKKKNQELEKFK-----FVL----DHRIEQFK--KQIESRENDI---KIMQKQIHEMERELEQLHKENTQLKLN 1012
Cdd:PRK05771 158 EELKLESDVENVEYISTDkgyvyVVVvvlkELSDEVEEelKKLGFERLELeeeGTPSELIREIKEELEEIEKERESLLEE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1013 ITQLQQK----LKATDNELHKERQKkqnMEALIKrFKMDLHNCV--GFI--QDYKKLKAGIRELYTKYVqqleMVEMEEV 1084
Cdd:PRK05771 238 LKELAKKyleeLLALYEYLEIELER---AEALSK-FLKTDKTFAieGWVpeDRVKKLKELIDKATGGSA----YVEFVEP 309
|
...
gi 2024426573 1085 DTD 1087
Cdd:PRK05771 310 DEE 312
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
676-946 |
6.10e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 6.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 676 EEVLIMKSDIEEKSRTILDLQIRVKELQIE-NDYQLRLKDM-----SCYEKIKELEETFTQELESL-KNKHQILQAEKDN 748
Cdd:TIGR02168 789 AQIEQLKEELKALREALDELRAELTLLNEEaANLRERLESLerriaATERRLEDLEEQIEELSEDIeSLAAEIEELEELI 868
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 749 QEMQHQLQ-LSELMNKHAKEM---RDLESDSNQKLLMENEKYQELQVDSQRMQEEYEKQLHNLQESKNRtveelTDYYEE 824
Cdd:TIGR02168 869 EELESELEaLLNERASLEEALallRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR-----IDNLQE 943
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 825 KLNEK-SLLLEEAEEdmrqqlqaHEEIKKQIEEDEDREIQDIKIKYErwlieekesnlqlkgEIGVMNkrLNSLQ--KEL 901
Cdd:TIGR02168 944 RLSEEySLTLEEAEA--------LENKIEDDEEEARRRLKRLENKIK---------------ELGPVN--LAAIEeyEEL 998
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 2024426573 902 KERnndIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEK 946
Cdd:TIGR02168 999 KER---YDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQ 1040
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
895-1027 |
6.57e-05 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 45.28 E-value: 6.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 895 NSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDIsmlntniekrtntiQEKEKHIYDLKKKNQELEKFKF--------V 966
Cdd:pfam15619 56 SELPQLIARHNEEVRVLRERLRRLQEKERDLERKL--------------KEKEAELLRLRDQLKRLEKLSEdknlaereE 121
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 967 LDHRIEQFKKQIESRENDIKIMQKQIHEMERELE-QLHKEN-----TQLKLNITQ-----LQQKLKATDNEL 1027
Cdd:pfam15619 122 LQKKLEQLEAKLEDKDEKIQDLERKLELENKSFRrQLAAEKkkhkeAQEEVKILQeeierLQQKLKEKEREL 193
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
823-1143 |
6.77e-05 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 46.94 E-value: 6.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 823 EEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDE---DREIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQK 899
Cdd:pfam05667 239 EYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAqdlAELLSSFSGSSTTDTGLTKGSRFTHTEKLQFTNEAPAATSS 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 900 ELKERNNdIEDMKLEQQ----NLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKfkfvldhrieqfk 975
Cdd:pfam05667 319 PPTKVET-EEELQQQREeeleELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEK------------- 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 976 kqiesrENDIKimqKQIHEMERELEQlhkentqlklNITQLQQKLKATdnelhkeRQKKQNMEALIKRFKMDLhncvgfI 1055
Cdd:pfam05667 385 ------QYKVK---KKTLDLLPDAEE----------NIAKLQALVDAS-------AQRLVELAGQWEKHRVPL------I 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1056 QDYKKLKAGIRELYTKYVQQLEmvEMEEVDTDLQQ--EYMRQREYLERNLAALKKKVVKDqeVHQAAYT-RIMQenvsLI 1132
Cdd:pfam05667 433 EEYRALKEAKSNKEDESQRKLE--EIKELREKIKEvaEEAKQKEELYKQLVAEYERLPKD--VSRSAYTrRILE----IV 504
|
330
....*....|.
gi 2024426573 1133 KEINDLRQELT 1143
Cdd:pfam05667 505 KNIKKQKEEIT 515
|
|
| Tht1 |
pfam04163 |
Tht1-like nuclear fusion protein; |
716-1036 |
6.95e-05 |
|
Tht1-like nuclear fusion protein;
Pssm-ID: 282073 Cd Length: 595 Bit Score: 47.13 E-value: 6.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 716 SCYEKIKELEETFTQELESLKNKHQILQ-AEKDNQEMQHQLQLSELMN---KHAKEMRDLESDSNQKLLMENEKYQELQV 791
Cdd:pfam04163 123 SMMDCMFELESSSQWWLSFSGHFHDLNHiCREALLEFEKELIIELFLNiteLQDQFGDDLDMKILHLMFQMEQDFENFLD 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 792 DSQRMQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEaeedmrqqLQAHEEikkqieEDEDREIQDIkikyer 871
Cdd:pfam04163 203 DLAQMFDKFDGEFNNATESNRIIIENDFKDFNFKVNDEIMGLVE--------LENHEQ------EGMVLEKEII------ 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 872 wlieekESNLQLKGEIGVMNKRLNSLQKE-------LKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQ 944
Cdd:pfam04163 263 ------EKIKQLKNEIDDIHHFFADFADElagykndIIEKINDLKDDSENAIALSAIGKYTSEFSAFMEKNIKDLIEMSE 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 945 EKEKHIYDLKKK-----NQELEKFKFvldhrieQFKKQIESRENDIKimQKQIHEMERELEQLHKENTQLKLNITQLQQk 1019
Cdd:pfam04163 337 DSLKESVQRNIDfvnsgFQELEDFSI-------GLKEELGGLKKDLS--EQQNLEAEEILQWKSDFLNILHDHLKVLQQ- 406
|
330
....*....|....*..
gi 2024426573 1020 LKATDNELHKERQKKQN 1036
Cdd:pfam04163 407 LPPLIDEIVPEMEKFKN 423
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
740-1031 |
6.98e-05 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 47.14 E-value: 6.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 740 QILQAEKDNQEMQHQLQlsELMNKHAK------EMRDLESDSNQKLLMENEKY----QELQVDSQRMQEEYEkQLHNLQE 809
Cdd:PRK04778 113 LLDLIEEDIEQILEELQ--ELLESEEKnreeveQLKDLYRELRKSLLANRFSFgpalDELEKQLENLEEEFS-QFVELTE 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 810 SKN--------RTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQ----AHEEIKKQ---IEEDE-DREIQDIKIKYERwl 873
Cdd:PRK04778 190 SGDyveareilDQLEEELAALEQIMEEIPELLKELQTELPDQLQelkaGYRELVEEgyhLDHLDiEKEIQDLKEQIDE-- 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 874 IEEKESNLQLKG---EIGVMNKRLNSL----QKELKERNNdiedMKLEQQNLQGIIKSLEKDISMLNTNIE--KRTNTIQ 944
Cdd:PRK04778 268 NLALLEELDLDEaeeKNEEIQERIDQLydilEREVKARKY----VEKNSDTLPDFLEHAKEQNKELKEEIDrvKQSYTLN 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 945 EKEKHIY-DLKKKNQELEKFKFVLDHRIEQFK----------KQIESRENDIKIMQKQIHEMereLEQLHKENTQLKLNI 1013
Cdd:PRK04778 344 ESELESVrQLEKQLESLEKQYDEITERIAEQEiayselqeelEEILKQLEEIEKEQEKLSEM---LQGLRKDELEAREKL 420
|
330
....*....|....*...
gi 2024426573 1014 TQLQQKLKATDNELHKER 1031
Cdd:PRK04778 421 ERYRNKLHEIKRYLEKSN 438
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
661-1040 |
7.06e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.12 E-value: 7.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 661 KKGKILKR--EKEFEYAEEVLIMKSDIEEKSRTILDLQIRVKELQiendYQLRLKDmscyekikeleetftQELESLKNK 738
Cdd:pfam10174 363 KKTKQLQDltEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQ----EQLRDKD---------------KQLAGLKER 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 739 HQILQAEKDNQEMQhqlqLSELMNKHAKEMRDLESDSNQKLLMENEKYQELqvdsqrmqEEYEKQLHNLQESKNRTVEEL 818
Cdd:pfam10174 424 VKSLQTDSSNTDTA----LTTLEEALSEKERIIERLKEQREREDRERLEEL--------ESLKKENKDLKEKVSALQPEL 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 819 TDyyeeklNEKSLL-LEEAEEDMRQQLQAHEEIKKQIE-EDEDREIQDIKIKYERWLIEEKESNLQLKGEIgvmNKRLNS 896
Cdd:pfam10174 492 TE------KESSLIdLKEHASSLASSGLKKDSKLKSLEiAVEQKKEECSKLENQLKKAHNAEEAVRTNPEI---NDRIRL 562
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 897 LQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNI---EKRTNTiQEKEKHIYDLKKKNQELEKFKFVLDHRIEQ 973
Cdd:pfam10174 563 LEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIaelESLTLR-QMKEQNKKVANIKHGQQEMKKKGAQLLEEA 641
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 974 FKKQIESRENDikiMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQ--KKQNMEAL 1040
Cdd:pfam10174 642 RRREDNLADNS---QQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAerRKQLEEIL 707
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
942-1141 |
7.61e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.69 E-value: 7.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 942 TIQEKEKHIYDLkkknQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLk 1021
Cdd:COG1579 1 AMPEDLRALLDL----QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1022 atdnelhKERQKKQNMealikrfkmdlhncvgfIQDYKKLKAGIRELYTkyvQQLEMVEMEEVdtdlQQEYMRQREYLER 1101
Cdd:COG1579 76 -------KKYEEQLGN-----------------VRNNKEYEALQKEIES---LKRRISDLEDE----ILELMERIEELEE 124
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2024426573 1102 NLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLRQE 1141
Cdd:COG1579 125 ELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
666-1109 |
7.70e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 47.35 E-value: 7.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 666 LKREKEFEYAEEVLIMKSDIEEKSRTILDLQIRVKElQIENDYQL------RLKDMSCYEKIKELEETFTQELESLKNKH 739
Cdd:TIGR01612 825 IKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKE-KIDSEHEQfaeltnKIKAEISDDKLNDYEKKFNDSKSLINEIN 903
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 740 QILQAEKDN----QEMQHQLQLSELMNKHAKEMRDLESDSNQKLlmeNEKYQELQvDSQRMQEEYEKQLHN-LQESKNRT 814
Cdd:TIGR01612 904 KSIEEEYQNintlKKVDEYIKICENTKESIEKFHNKQNILKEIL---NKNIDTIK-ESNLIEKSYKDKFDNtLIDKINEL 979
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 815 VEELTDY----YEEKLNEksllLEEAEEDMRQQLQAHEE--IKKQIEEDEdREIQDIkikyerwliEEKESNLqlkgeig 888
Cdd:TIGR01612 980 DKAFKDAslndYEAKNNE----LIKYFNDLKANLGKNKEnmLYHQFDEKE-KATNDI---------EQKIEDA------- 1038
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 889 vmNKRLNSLQKELKERNNDIEDmklEQQNLQGiiksleKDISMLNTNIEKRTNT-------IQEKEKHiYDLKkknqele 961
Cdd:TIGR01612 1039 --NKNIPNIEIAIHTSIYNIID---EIEKEIG------KNIELLNKEILEEAEInitnfneIKEKLKH-YNFD------- 1099
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 962 kfKFVLDHRIeQFKKQIESRENDIKIMQKQIHEMERELEQLHK--EN--TQLKLNITQLQQKL-KATDNELHKERQKK-Q 1035
Cdd:TIGR01612 1100 --DFGKEENI-KYADEINKIKDDIKNLDQKIDHHIKALEEIKKksENyiDEIKAQINDLEDVAdKAISNDDPEEIEKKiE 1176
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1036 NMEALIKRFKM---DLHNCVGFIQDYKKLKAGIRE---LYTKYVQQLEMVEMEEVDTDLQQ-EYM-RQREYLERNLAALK 1107
Cdd:TIGR01612 1177 NIVTKIDKKKNiydEIKKLLNEIAEIEKDKTSLEEvkgINLSYGKNLGKLFLEKIDEEKKKsEHMiKAMEAYIEDLDEIK 1256
|
..
gi 2024426573 1108 KK 1109
Cdd:TIGR01612 1257 EK 1258
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
666-1000 |
9.21e-05 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 46.86 E-value: 9.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 666 LKREK-EFEYAEEvlIMKSDIEEKSRTILDLQIRVKELQ-----IENDYQLRLKDMSCYEK-IKELEE---TFTQELESL 735
Cdd:pfam15818 76 LEEEKgKYQLATE--IKEKEIEGLKETLKALQVSKYSLQkkvseMEQKLQLHLLAKEDHHKqLNEIEKyyaTITGQFGLV 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 736 KNKHQILqaEKDNQE-MQHQLQLSELMNKH-------AKEMRDLESD--------------SNQKLLMENEKYQELQvDS 793
Cdd:pfam15818 154 KENHGKL--EQNVQEaIQLNKRLSALNKKQeseicslKKELKKVTSDlikskvtcqykmgeENINLTIKEQKFQELQ-ER 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 794 QRMQEEYEKQLHnlqesknrtvEELTDYYEEKLNEKSlLLEEAEEDMRQQLQAHEEIK---KQIEED-----EDREIQDI 865
Cdd:pfam15818 231 LNMELELNKKIN----------EEITHIQEEKQDIII-SFQHMQQLLQQQTQANTEMEaelKALKENnqtleRDNELQRE 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 866 KIKYErwliEEKESNLQlkgeigvmnkrlNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKdismlnTNIEkrtntIQE 945
Cdd:pfam15818 300 KVKEN----EEKFLNLQ------------NEHEKALGTWKKHVEELNGEINEIKNELSSLKE------THIK-----LQE 352
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2024426573 946 KEKHIYDlKKKNQELEKFKFVldHRIEQFKKQIESRENDIKIMQKQIHEMERELE 1000
Cdd:pfam15818 353 HYNKLCN-QKKFEEDKKFQNV--PEVNNENSEMSTEKSENLIIQKYNSEQEIREE 404
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
883-1176 |
9.21e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 46.06 E-value: 9.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 883 LKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLekdISMLNTNIEKRTNTIQEKEKHIYDLKKKNQEL-E 961
Cdd:COG1340 13 LEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKEL---REEAQELREKRDELNEKVKELKEERDELNEKLnE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 962 KFKFVLDHRIEQfkKQIESRENDIKIMQKQIHEMERELE----QLHKENtQLKLNITQLQQKLKATDnELHKERQKKQNM 1037
Cdd:COG1340 90 LREELDELRKEL--AELNKAGGSIDKLRKEIERLEWRQQtevlSPEEEK-ELVEKIKELEKELEKAK-KALEKNEKLKEL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1038 EALIKRFKMDLhncvgfiQDYKKLKAGIRELYTKYVQQLemvemeevdtdlqQEYMRQREYLERNLAALKKKVVKDQEVH 1117
Cdd:COG1340 166 RAELKELRKEA-------EEIHKKIKELAEEAQELHEEM-------------IELYKEADELRKEADELHKEIVEAQEKA 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 1118 QAAYTRIMQenvsLIKEINDLRQELTVAHTQVHDLQSAL---KLTKKKQAIQDTAPSNETLS 1176
Cdd:COG1340 226 DELHEEIIE----LQKELRELRKELKKLRKKQRALKREKekeELEEKAEEIFEKLKKGEKLT 283
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
898-1165 |
9.56e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 46.82 E-value: 9.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 898 QKELKERNNDIEDMKLEQQNLQGIIKSLEKDISmlntNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQ 977
Cdd:PRK01156 151 RKKILDEILEINSLERNYDKLKDVIDMLRAEIS----NIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIE 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 978 IESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATD--NELHKERQKKQNMEALIKRFKM-DLHNCVGF 1054
Cdd:PRK01156 227 YNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNyyKELEERHMKIINDPVYKNRNYInDYFKYKND 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1055 IQDYKKLKAGIRELYTKYvqQLEMVEMEEVDTDLQQEYMRQREYLERNlaalkkKVVKDQEVHQAAYtrimqenVSLIKE 1134
Cdd:PRK01156 307 IENKKQILSNIDAEINKY--HAIIKKLSVLQKDYNDYIKKKSRYDDLN------NQILELEGYEMDY-------NSYLKS 371
|
250 260 270
....*....|....*....|....*....|.
gi 2024426573 1135 INDLRQELTVAHTQVHDLQSALKLTKKKQAI 1165
Cdd:PRK01156 372 IESLKKKIEEYSKNIERMSAFISEILKIQEI 402
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
823-1157 |
9.84e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 46.76 E-value: 9.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 823 EEKLNEKSLLLEEAEEDMRQQLQAHEE----IKKQIEEdEDREIQDIKIKYE------RWLIEEKES-----NLQLKGEI 887
Cdd:pfam12128 599 EEELRERLDKAEEALQSAREKQAAAEEqlvqANGELEK-ASREETFARTALKnarldlRRLFDEKQSekdkkNKALAERK 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 888 GVMNKRLNSLQKELKERNNDIEDMKLEQQNlqgiikslekdismlntniEKRTNTIQEKEKHiydlkkknQELEKfkfVL 967
Cdd:pfam12128 678 DSANERLNSLEAQLKQLDKKHQAWLEEQKE-------------------QKREARTEKQAYW--------QVVEG---AL 727
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 968 DHRIEQFKKQIESRENDIKimqkqihemeRELEQLHKENtqlklnitqlqqklkatDNELHK---ERQKKQNMEALIKRF 1044
Cdd:pfam12128 728 DAQLALLKAAIAARRSGAK----------AELKALETWY-----------------KRDLASlgvDPDVIAKLKREIRTL 780
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1045 KMDLHNCVGFIQDYKKLKAGIRELYT----KYVQQLEMVE--MEEVDTDL---QQEYMRQREYLERNLAALKKKVVKDQE 1115
Cdd:pfam12128 781 ERKIERIAVRRQEVLRYFDWYQETWLqrrpRLATQLSNIEraISELQQQLarlIADTKLRRAKLEMERKASEKQQVRLSE 860
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2024426573 1116 VHQAayTRIMQENVSLIKEINDLRQ-ELTVAHT--QVHDLQSALK 1157
Cdd:pfam12128 861 NLRG--LRCEMSKLATLKEDANSEQaQGSIGERlaQLEDLKLKRD 903
|
|
| mS26_Tt |
cd23695 |
Tetrahymena thermophila ribosomal protein mS26 and similar proteins; Ribosomal protein mS26 is ... |
703-1185 |
1.22e-04 |
|
Tetrahymena thermophila ribosomal protein mS26 and similar proteins; Ribosomal protein mS26 is a component of small subunit (SSU) in Tetrahymena thermophila mitochondrial ribosome (mitoribosome). The structure of the mitoribosome reveals an assembly of 94-ribosomal proteins and four-rRNAs with an additional protein mass of ~700 kDa on the small subunit; the large mitoribosomal subunit (LSU) lacks 5S rRNA.
Pssm-ID: 467909 [Multi-domain] Cd Length: 496 Bit Score: 45.97 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 703 QIENDYqlrlkdmscYEKIKElEETFTQELESLKNKHQILQAEKDNQEMQHQLqlselmnkhaKEMRDLESDSNQKLLME 782
Cdd:cd23695 31 IVENEF---------IDKYNK-EELKKQRKDLDKWRTSIITISKATQNHIKLL----------EKKSVKKEENERKYLLE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 783 N-----EKYQELQVdsqrMQEEyEKQLHNLQESKNRTVEEL---------TDYYEeKLNEKSLLLEEAEedmrqqlqaHE 848
Cdd:cd23695 91 QdvkamNKKIILDV----MNEE-SKNWINLQNMNEKINPNLilpdtildeTSYYL-KLQELAFLFEQGD---------HE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 849 EIKKQIEEDEDreiqdikikyerwlIEEKESNLQlkgeigVMNKRLNSLQKELKerNNDIEDMKLEQQNLQGIIkslekd 928
Cdd:cd23695 156 EMDKLLDENEE--------------IEYKNSLLM------PIYQDLKSLIKHLK--YTELFKLLKEYQDAKAII------ 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 929 ismlntnIEKRTNTIQEKEKHIYDLKKKNQELEKfkfvldhrieQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQ 1008
Cdd:cd23695 208 -------IEDFRESSEEGAEKLEKLEKAFATLLK----------NYKEELEEPEKQLEFMQKRLLDLYNLLRLWGQYITI 270
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1009 LKLNITQLQQKLKATDNELHK-ERQKKQNMEALIKRFKMDLHNcvGFIQDYKKLKAGIRELytkyvqqlEMVEMEEVDTD 1087
Cdd:cd23695 271 VKMPDSVVRDIMNKTQARPEVaKLNSKQELEDAKNRKRDTEEN--EFDDDYESADEGETSD--------EEDEIEEENFQ 340
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1088 LQQE-YMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEIND--LRQELTVAHTQVHDLQSALKLTKKKQA 1164
Cdd:cd23695 341 LQKEkKKEEELNAEFNIAKNSLYKFSPQNDKNVVDDRDFYSGVDLENVFPRalLNNLNDFTGLDFQNVKEILNNEEKLKI 420
|
490 500
....*....|....*....|.
gi 2024426573 1165 IQDTAPSNETLSSPAVLRLNA 1185
Cdd:cd23695 421 IQGEDDQNDQEDFNNPRKFQT 441
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
719-925 |
1.39e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 46.29 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEET----FTQELESLKN-------KHQILQAEKDNQEMQH-QLQLselmNKHAKEMRDLESDSNQKLLMENEKy 786
Cdd:pfam09731 246 DQYKELVASerivFQQELVSIFPdiipvlkEDNLLSNDDLNSLIAHaHREI----DQLSKKLAELKKREEKHIERALEK- 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 787 QELQVD------SQRMQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKsllLEEAEEDMRQQLQahEEIKKQIEEDEDR 860
Cdd:pfam09731 321 QKEELDklaeelSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTE---LERQAEAHEEHLK--DVLVEQEIELQRE 395
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024426573 861 EIQDIKIKyerwlIEEKESNLQLKgeIGVMNKRLNSLQKELKERnNDIEDMKLEQQNLQGIIKSL 925
Cdd:pfam09731 396 FLQDIKEK-----VEEERAGRLLK--LNELLANLKGLEKATSSH-SEVEDENRKAQQLWLAVEAL 452
|
|
| DUF4659 |
pfam15558 |
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ... |
700-882 |
1.52e-04 |
|
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.
Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 45.41 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 700 KELQIENDYQLRLKDMSCYEKiKELEETFTQELESLKNKHQILQAEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQKL 779
Cdd:pfam15558 137 QALREQNSLQLQERLEEACHK-RQLKEREEQKKVQENNLSELLNHQARKVLVDCQAKAEELLRRLSLEQSLQRSQENYEQ 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 780 LMEnEKYQELQVDSQRMQEEyekqlhnLQESKNRTVEeltdYYEEKLNEKSLLLEEAEEDMRQQLQA------------- 846
Cdd:pfam15558 216 LVE-ERHRELREKAQKEEEQ-------FQRAKWRAEE----KEEERQEHKEALAELADRKIQQARQVahktvqdkaqrar 283
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2024426573 847 ---------HEEIKKQIEEDED---REI-QDIKIKYER--WLIEEKESNLQ 882
Cdd:pfam15558 284 elnlereknHHILKLKVEKEEKchrEGIkEAIKKKEQRseQISREKEATLE 334
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
729-1120 |
1.59e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 46.32 E-value: 1.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 729 TQEL------ESLKNKHQILQAEKDNQEMQHQLQLSElmnkHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEK 802
Cdd:pfam01576 473 TQELlqeetrQKLNLSTRLRQLEDERNSLQEQLEEEE----EAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 803 QLHNLQESKNRTVEELTDYYEeKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDreiqdikiKYERWLIEEKESNLQ 882
Cdd:pfam01576 549 RLQRELEALTQQLEEKAAAYD-KLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQK--------KFDQMLAEEKAISAR 619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 883 LKGEigvmnkrLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEkrtNTIQEKEkhiyDLKKKNQELEK 962
Cdd:pfam01576 620 YAEE-------RDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEME---DLVSSKD----DVGKNVHELER 685
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 963 FKFVLDHRIEQFKKQIESRENDIKI-----------MQKQIHEMERELEQLHKENTQLKlniTQLQQKLKATDNELHKER 1031
Cdd:pfam01576 686 SKRALEQQVEEMKTQLEELEDELQAtedaklrlevnMQALKAQFERDLQARDEQGEEKR---RQLVKQVRELEAELEDER 762
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1032 QKKQNMEALIKRFKMDLHNCVGFIQDYKKLkagiRELYTKYVQQLEmVEMEEVDTDLQQEYMRQREYL------ERNLAA 1105
Cdd:pfam01576 763 KQRAQAVAAKKKLELDLKELEAQIDAANKG----REEAVKQLKKLQ-AQMKDLQRELEEARASRDEILaqskesEKKLKN 837
|
410
....*....|....*
gi 2024426573 1106 LKKKVVKDQEVHQAA 1120
Cdd:pfam01576 838 LEAELLQLQEDLAAS 852
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
986-1169 |
1.80e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 1.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 986 KIMQKQIHEMERELEQLHKENTQLKlnitQLQQKLKATDNELHKERQKKQNMEALIKRFKmDLHNCVGFIQDYKKLKAGI 1065
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYA----ELQEELEELEEELEELEAELEELREELEKLE-KLLQLLPLYQELEALEAEL 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1066 RELYTKY----VQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLRQE 1141
Cdd:COG4717 142 AELPERLeeleERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180
....*....|....*....|....*...
gi 2024426573 1142 LTVAHTQVHDLQSALKLTKKKQAIQDTA 1169
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEAR 249
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
623-657 |
1.86e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 39.99 E-value: 1.86e-04
10 20 30
....*....|....*....|....*....|....*
gi 2024426573 623 NEYQAHAGAITKMSVTNDDLFLLTASEDGSIFFWK 657
Cdd:smart00320 6 KTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
686-1020 |
2.03e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 45.94 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 686 EEKSRTILDlQIRVKELQIENDYQLRLKDMSCYEKIkeleETFTQELESlknkhQILQAEKDNQEMQHQL-QLSELMNKH 764
Cdd:pfam01576 741 EEKRRQLVK-QVRELEAELEDERKQRAQAVAAKKKL----ELDLKELEA-----QIDAANKGREEAVKQLkKLQAQMKDL 810
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 765 AKEMRDLESDSNQKLLM--ENE-KYQELQVDSQRMQEEyekqlHNLQESKNRTVE----ELTDYYEEKLNEKSLLLEEAE 837
Cdd:pfam01576 811 QRELEEARASRDEILAQskESEkKLKNLEAELLQLQED-----LAASERARRQAQqerdELADEIASGASGKSALQDEKR 885
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 838 EDMRQQLQAHEEIkkqieEDEDREIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSlqKELKERNNdiEDMKLEQQN 917
Cdd:pfam01576 886 RLEARIAQLEEEL-----EEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESA--RQQLERQN--KELKAKLQE 956
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 918 LQGIIKS--------LEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQEL-----------EKFKFVLDH---RIEQFK 975
Cdd:pfam01576 957 MEGTVKSkfkssiaaLEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVllqvederrhaDQYKDQAEKgnsRMKQLK 1036
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2024426573 976 KQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKL 1020
Cdd:pfam01576 1037 RQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSKL 1081
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
892-1167 |
2.68e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 892 KRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTniekrtntIQEKEKHIYDLKKKNQELEkfkfvldhRI 971
Cdd:COG4913 610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQR--------LAEYSWDEIDVASAEREIA--------EL 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 972 EQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIkrfkmdlhnc 1051
Cdd:COG4913 674 EAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLA---------- 743
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1052 vgfiqdykklKAGIRELYTKYVQQLemvEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSL 1131
Cdd:COG4913 744 ----------RLELRALLEERFAAA---LGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDAD 810
|
250 260 270
....*....|....*....|....*....|....*..
gi 2024426573 1132 IKEINDLRQELT-VAHTQVHDLQSALKLTKKKQAIQD 1167
Cdd:COG4913 811 LESLPEYLALLDrLEEDGLPEYEERFKELLNENSIEF 847
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
942-1119 |
3.01e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 3.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 942 TIQEKEKHIYDLKKKNQELEkfkfVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLN-ITQLQQKL 1020
Cdd:COG4913 272 AELEYLRAALRLWFAQRRLE----LLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLEREI 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1021 KATDNELHKERQKKQNMEALIKRFKMDLhncVGFIQDYKKLKAGIRELYTKYVQQLEMVEMEEVDT-DLQQEYMRQREYL 1099
Cdd:COG4913 348 ERLERELEERERRRARLEALLAALGLPL---PASAEEFAALRAEAAALLEALEEELEALEEALAEAeAALRDLRRELREL 424
|
170 180
....*....|....*....|.
gi 2024426573 1100 ERNLAALKK-KVVKDQEVHQA 1119
Cdd:COG4913 425 EAEIASLERrKSNIPARLLAL 445
|
|
| Nup88 |
pfam10168 |
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ... |
725-911 |
3.17e-04 |
|
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.
Pssm-ID: 462975 [Multi-domain] Cd Length: 713 Bit Score: 45.04 E-value: 3.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 725 EETFTQELESL--KNKHQ-ILQAEKDNQEMQHQ-LQL---------SELMNKH-------AKEMRDLESDSNQKL----L 780
Cdd:pfam10168 500 EDSFEDHIKSIlqRSVSNpILSADKLSSPSPQEcLQLlsratqvfrEEYLKKHdlareeiQKRVKLLKLQKEQQLqelqS 579
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 781 MENEKyQELQVDSQRMQEEYEkQLHNLQESKNRTVEELTdyyeEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIeedeDR 860
Cdd:pfam10168 580 LEEER-KSLSERAEKLAEKYE-EIKDKQEKLMRRCKKVL----QRLNSQLPVLSDAEREMKKELETINEQLKHL----AN 649
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 861 EIQDIKIK--YERWLIEEKESNLQlKGEIGVMNKRLNSLQKELKERNNDIEDM 911
Cdd:pfam10168 650 AIKQAKKKmnYQRYQIAKSQSIRK-KSSLSLSEKQRKTIKEILKQLGSEIDEL 701
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
376-408 |
3.81e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 39.22 E-value: 3.81e-04
10 20 30
....*....|....*....|....*....|...
gi 2024426573 376 FPLHSASITGLDVCIRRPIVATCSLDKSVRVWN 408
Cdd:smart00320 8 LKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
798-932 |
3.97e-04 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 44.36 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 798 EEYEKQLHNLQE---SKNRTVEEltdyYEEKL------NEKSLL-----LEEAEEDMRQQlQaheeikkqieededreiq 863
Cdd:pfam12004 388 EKYEQEISKLKErlrVSNRKLEE----YERRLlaqeeqTQKLLLeyqarLEDSEERLRRQ-Q------------------ 444
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 864 dikikyerwliEEKESnlQLKGEIGvmnkRLNSLQKELKernNDIEDMKLEQQNLQGIIKSLEKDISML 932
Cdd:pfam12004 445 -----------EEKDS--QMKSIIS----RLMAVEEELK---KDHAEMQAVIDSKQKIIDAQEKRIASL 493
|
|
| ADIP |
pfam11559 |
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ... |
932-1045 |
3.97e-04 |
|
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.
Pssm-ID: 463295 [Multi-domain] Cd Length: 151 Bit Score: 42.30 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 932 LNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKfvldhriEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKL 1011
Cdd:pfam11559 22 LFDTAEGVEENIARIINVIYELLQQRDRDLEFR-------ESLNETIRTLEAEIERLQSKIERLKTQLEDLERELALLQA 94
|
90 100 110
....*....|....*....|....*....|....
gi 2024426573 1012 NITQLQQKLKATDNELHKERQKKQNMEALIKRFK 1045
Cdd:pfam11559 95 KERQLEKKLKTLEQKLKNEKEELQRLKNALQQIK 128
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
710-919 |
4.20e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 43.85 E-value: 4.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 710 LRLKDMSCYE---KIKELEETFTQ-ELESLKNKHQILQ-----AEKDNQEMQHQLQLSELMNK-HAKEM---------RD 770
Cdd:smart00787 65 LELYQFSCKElkkYISEGRDLFKEiEEETLINNPPLFKeyfsaSPDVKLLMDKQFQLVKTFARlEAKKMwyewrmkllEG 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 771 LESDSNQKLLMENEKYQELQVDSQRMQEEYEKqLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEI 850
Cdd:smart00787 145 LKEGLDENLEGLKEDYKLLMKELELLNSIKPK-LRDRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLKKLLQEIMIK 223
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 851 KKQIEEDEdREIQDIKIKYErwliEEKESNLQLKGEIgvmnkrlNSLQKELKERN----NDIEDMKLEQQNLQ 919
Cdd:smart00787 224 VKKLEELE-EELQELESKIE----DLTNKKSELNTEI-------AEAEKKLEQCRgftfKEIEKLKEQLKLLQ 284
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
719-991 |
4.38e-04 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 43.79 E-value: 4.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEETFTQELESLKNKH-QILQAEKDNQEMQHQLQLSELMNKHAKEMRD-LESDSN--QKllmENEKYQElqvDSQ 794
Cdd:pfam09728 18 EKLAALCKKYAELLEEMKRLQkDLKKLKKKQDQLQKEKDQLQSELSKAILAKSkLEKLCRelQK---QNKKLKE---ESK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 795 RMQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEaEEDMRQQLQAHEEIKKQIEEDEDR-------EIQDIKI 867
Cdd:pfam09728 92 KLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREE-NEELREKLKSLIEQYELRELHFEKllktkelEVQLAEA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 868 KYERWLIEE----------------------KESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSL 925
Cdd:pfam09728 171 KLQQATEEEekkaqekevakarelkaqvqtlSETEKELREQLNLYVEKFEEFQDTLNKSNEVFTTFKKEMEKMSKKIKKL 250
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024426573 926 EKDISMLNTNIEKrTNtiqekeKHIYDLKKKNQELEKfkfvldhRIEQFKKQIESRENDIKIMQKQ 991
Cdd:pfam09728 251 EKENLTWKRKWEK-SN------KALLEMAEERQKLKE-------ELEKLQKKLEKLENLCRALQAE 302
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
662-1154 |
4.54e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 44.65 E-value: 4.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 662 KGKILKREKEFEYAEEVLIMKSDI----EEKSRTILDLQIRVKELQiendyqlrlkdmscyEKIKELE---ETFTQELES 734
Cdd:PRK02224 219 DEEIERYEEQREQARETRDEADEVleehEERREELETLEAEIEDLR---------------ETIAETErerEELAEEVRD 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 735 LKNkhQILQAEKDNQEMQHQLQLSELMNKHAKEMRD-LESDsnqkllmENEKYQELQvDSQRMQEEYEKQLHNLQESKnR 813
Cdd:PRK02224 284 LRE--RLEELEEERDDLLAEAGLDDADAEAVEARREeLEDR-------DEELRDRLE-ECRVAAQAHNEEAESLREDA-D 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 814 TVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDReIQDIKIKYERwLIEEKESNLQLKGEIgvmNKR 893
Cdd:PRK02224 353 DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRER-FGDAPVDLGN-AEDFLEELREERDEL---RER 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 894 LNSLQKELKERNNDIEDMK--LEQ-------QNLQGI------------IKSLEKDISMLNTNIEKRTNTI------QEK 946
Cdd:PRK02224 428 EAELEATLRTARERVEEAEalLEAgkcpecgQPVEGSphvetieedrerVEELEAELEDLEEEVEEVEERLeraedlVEA 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 947 EKHIYDLKKKNQELEKfkfvldhRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNE 1026
Cdd:PRK02224 508 EDRIERLEERREDLEE-------LIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1027 LHKERQKKQNMEALIKRFKmDLHNCVGFIQDYKKLKAGIRELYTK----------YVQQLEmvemEEVD----TDLQQEY 1092
Cdd:PRK02224 581 LAELKERIESLERIRTLLA-AIADAEDEIERLREKREALAELNDErrerlaekreRKRELE----AEFDeariEEAREDK 655
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 1093 MRQREYLERNLAALKKKVVKDQEVhQAAYTRIMQEnvslIKEINDLRQELTVAHTQVHDLQS 1154
Cdd:PRK02224 656 ERAEEYLEQVEEKLDELREERDDL-QAEIGAVENE----LEELEELRERREALENRVEALEA 712
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
720-1027 |
4.83e-04 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 44.46 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 720 KIKELEETFTQELESL--KNKHQILQAEKDNQEMQhQLQLSELMNKHAKEMRDLESDS------NQKLLMENEKYQELQV 791
Cdd:PLN03229 422 KKREAVKTPVRELEGEveKLKEQILKAKESSSKPS-ELALNEMIEKLKKEIDLEYTEAviamglQERLENLREEFSKANS 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 792 DSQRMQEEYEKQLHNLQESKNRTVEELTDYYE-----EKLNEKSLLLEEAEEDMR-QQLQAheEIKKQIEEDEDREiqDI 865
Cdd:PLN03229 501 QDQLMHPVLMEKIEKLKDEFNKRLSRAPNYLSlkyklDMLNEFSRAKALSEKKSKaEKLKA--EINKKFKEVMDRP--EI 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 866 KIKYERWLIEEKESNLQLKGEigvmnkrlnsLQKELKERnndIEDMKLE-QQNLQGIIKSLEKDISMLNT-NIEKRTNTI 943
Cdd:PLN03229 577 KEKMEALKAEVASSGASSGDE----------LDDDLKEK---VEKMKKEiELELAGVLKSMGLEVIGVTKkNKDTAEQTP 643
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 944 QE--KEKhIYDLKKK-NQELEKFKFV--LDHRIEQFKKQIE--SRENDIKIMQKQihemeRELEQLHKENTQLKLNITQL 1016
Cdd:PLN03229 644 PPnlQEK-IESLNEEiNKKIERVIRSsdLKSKIELLKLEVAkaSKTPDVTEKEKI-----EALEQQIKQKIAEALNSSEL 717
|
330
....*....|.
gi 2024426573 1017 QQKLKATDNEL 1027
Cdd:PLN03229 718 KEKFEELEAEL 728
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
749-1097 |
5.29e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.40 E-value: 5.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 749 QEMQHQLQLSELMNKHAK-EMRDLES--DSNQKLLMENEKYQ---ELQVDSQRMQ-EEYEKQLHNLQESKNR---TVEEL 818
Cdd:pfam01576 646 EEALEAKEELERTNKQLRaEMEDLVSskDDVGKNVHELERSKralEQQVEEMKTQlEELEDELQATEDAKLRlevNMQAL 725
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 819 TDYYEEKLNEKSlllEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKyerwliEEKESNLQ-LKGEIGVMN------ 891
Cdd:pfam01576 726 KAQFERDLQARD---EQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAK------KKLELDLKeLEAQIDAANkgreea 796
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 892 -KRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHiydlkKKNQELEKfkfvlDHR 970
Cdd:pfam01576 797 vKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERA-----RRQAQQER-----DEL 866
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 971 IEQFKKQIESR---ENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKER---QK----KQNMEAL 1040
Cdd:pfam01576 867 ADEIASGASGKsalQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERstsQKsesaRQQLERQ 946
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2024426573 1041 IKRFKMDLHNCVGFIQdyKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQRE 1097
Cdd:pfam01576 947 NKELKAKLQEMEGTVK--SKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTE 1001
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
737-970 |
6.06e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 43.85 E-value: 6.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 737 NKHQILQAEKDNQEMQHQLQLSE----LMNKHAKEMRDLESDSNQKLlmeNEKYQELQvdsqRMQEEYEKQLHNLQESKN 812
Cdd:PHA02562 172 NKDKIRELNQQIQTLDMKIDHIQqqikTYNKNIEEQRKKNGENIARK---QNKYDELV----EEAKTIKAEIEELTDELL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 813 RTVEELTDYYEE--KLNEKSLLLEEAEEDMRQQLQAHEE------IKKQIEEDEDR------EIQDIKIKYErwLIEEKE 878
Cdd:PHA02562 245 NLVMDIEDPSAAlnKLNTAAAKIKSKIEQFQKVIKMYEKggvcptCTQQISEGPDRitkikdKLKELQHSLE--KLDTAI 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 879 SNLQLKgeigvMNKrLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQ 958
Cdd:PHA02562 323 DELEEI-----MDE-FNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKS 396
|
250
....*....|..
gi 2024426573 959 ELEKFKfvlDHR 970
Cdd:PHA02562 397 ELVKEK---YHR 405
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
379-408 |
7.03e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 38.48 E-value: 7.03e-04
10 20 30
....*....|....*....|....*....|
gi 2024426573 379 HSASITGLDVCIRRPIVATCSLDKSVRVWN 408
Cdd:pfam00400 10 HTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
686-1168 |
8.14e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.89 E-value: 8.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 686 EEKSRTILDLQIRVKELQIENDyqlrlkdmscyekIKELEETFTQELESLKNKHQIlqAEKDNQEMQHQLQLSELMNKHA 765
Cdd:TIGR01612 2058 KEKEKFGIDFDVKAMEEKFDND-------------IKDIEKFENNYKHSEKDNHDF--SEEKDNIIQSKKKLKELTEAFN 2122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 766 KEMRDLESdsnqKLLMENEKYQELQvdsqrmqeEYEKQLhnLQESKNRTVEELtdyyEEKLNEKSLLLEEAEEDMRQQLQ 845
Cdd:TIGR01612 2123 TEIKIIED----KIIEKNDLIDKLI--------EMRKEC--LLFSYATLVETL----KSKVINHSEFITSAAKFSKDFFE 2184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 846 AHEEIKKQIEEDEDreiqdikikyerwlieekesNLQLKGEIGVMNKRLNSLQKEL-KERNNDIEDMKLEQQnlqgIIKS 924
Cdd:TIGR01612 2185 FIEDISDSLNDDID--------------------ALQIKYNLNQTKKHMISILADAtKDHNNLIEKEKEATK----IINN 2240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 925 LEKDISMLNTNIEKRT---NTIQ------EKEKHIYDLKKKNQELEKFKFV---------------LDHRIEQFKKQIES 980
Cdd:TIGR01612 2241 LTELFTIDFNNADADIlhnNKIQiiyfnsELHKSIESIKKLYKKINAFKLLnishinekyfdiskeFDNIIQLQKHKLTE 2320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 981 RENDIKIMQKQIHEMERELEQLHKENTQLKLN--------ITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNCV 1052
Cdd:TIGR01612 2321 NLNDLKEIDQYISDKKNIFLHALNENTNFNFNalkeiyddIINRENKADEIENINNKENENIMQYIDTITKLTEKIQDIL 2400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1053 GFIQDYKKLKAGIRElytkYVQQLEMVEMEEVDTDLQQEyMRQREYLERNLAALKKKVVKDQEVHQAAYTriMQENVSLI 1132
Cdd:TIGR01612 2401 IFVTTYENDNNIIKQ----HIQDNDENDVSKIKDNLKKT-IQSFQEILNKIDEIKAQFYGGNNINNIIIT--ISQNANDV 2473
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 2024426573 1133 KEI--NDL--RQELTVAHTQVHDLQSALKLTKKKQAIQDT 1168
Cdd:TIGR01612 2474 KNHfsKDLtiENELIQIQKRLEDIKNAAHEIRSEQITKYT 2513
|
|
| MAP65_ASE1 |
pfam03999 |
Microtubule associated protein (MAP65/ASE1 family); |
777-1077 |
9.06e-04 |
|
Microtubule associated protein (MAP65/ASE1 family);
Pssm-ID: 427641 [Multi-domain] Cd Length: 477 Bit Score: 43.45 E-value: 9.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 777 QKLLME-NEKYQELQVDsqrmqEEYEKQLhnlqesKNRTVEELTDYYEEKLNEksllleeaEEDMRQQLQahEEIKKQIE 855
Cdd:pfam03999 1 EKLLDHlHVIWQEIGFS-----EDKRLQI------LSRLKDHIKEFYTDALSE--------ENDKEQRIL--QSIADLRA 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 856 EDED-REIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDIsmlnt 934
Cdd:pfam03999 60 EAAIlCLYMRNRLLHEERDPFEPKKGMSLLQKEKKLDTQLEHLRKEKAPRLAEIKELLEQLQQLCEELGEEPLPL----- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 935 niekrtntiqekekhiydLKKKNQELEKFKFVLDHrIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKL--- 1011
Cdd:pfam03999 135 ------------------LIDPLPSLEELESFRKH-LENLRNEKERRLEEVNELKKQIKLLMEELDLVPGTDFEEDLlce 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1012 ----------NITQLQQKLKATDNELHKERQKKQNMEALIK----RFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLE 1077
Cdd:pfam03999 196 sednfclsreNIDKLRKLIKQLEEQKAEREEKIDDLREKILelwnRLQVPQEEQESFVRENNSLSQDTIDALREELQRLE 275
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
842-1001 |
9.33e-04 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 41.80 E-value: 9.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 842 QQLQAHEEIKKQIEEDEDREIQDIKikyERWLIEEKESNLQLKGEIgvmnkrlnslQKELKERNNDIedMKLEQQNLQGi 921
Cdd:pfam12072 27 AKIGSAEELAKRIIEEAKKEAETKK---KEALLEAKEEIHKLRAEA----------ERELKERRNEL--QRQERRLLQK- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 922 ikslEKDISMLNTNIEKRTNTIQEKEKHiydLKKKNQELEKFKFVLDHRIEQFKKQIE-----SRENDIKIMqkqIHEME 996
Cdd:pfam12072 91 ----EETLDRKDESLEKKEESLEKKEKE---LEAQQQQLEEKEEELEELIEEQRQELErisglTSEEAKEIL---LDEVE 160
|
....*
gi 2024426573 997 RELEQ 1001
Cdd:pfam12072 161 EELRH 165
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
670-985 |
9.46e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.50 E-value: 9.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 670 KEFEYAEEVLIMKSDIEEKSRTILDLQIRVKELQIENDyqlrlKDMSCYEKIKELEETFTQELESLKNKHQILQAEKDN- 748
Cdd:TIGR00606 802 KDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELD-----TVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQi 876
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 749 -QEMQHQLQLSELMNKHAKEMRDLESDSNQKllmeNEKYQELQVDSQRMQEEYEKQLHNLQESKNRTVEELTDYYEEKLN 827
Cdd:TIGR00606 877 gTNLQRRQQFEEQLVELSTEVQSLIREIKDA----KEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKN 952
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 828 E----KSLL--LEEAEEDMRQ-----------QLQAHEEIKKQIEEDEDREIQDIKIKY--ERWL-------------IE 875
Cdd:TIGR00606 953 IhgymKDIEnkIQDGKDDYLKqketelntvnaQLEECEKHQEKINEDMRLMRQDIDTQKiqERWLqdnltlrkrenelKE 1032
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 876 EKESNLQLKGEIGVMnkRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDIsmLNTNIEKRTNTIQEKEKHIYDL-- 953
Cdd:TIGR00606 1033 VEEELKQHLKEMGQM--QVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI--KHFKKELREPQFRDAEEKYREMmi 1108
|
330 340 350
....*....|....*....|....*....|....*..
gi 2024426573 954 -----KKKNQELEKFKFVLDHRIEQFKKQIESRENDI 985
Cdd:TIGR00606 1109 vmrttELVNKDLDIYYKTLDQAIMKFHSMKMEEINKI 1145
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
889-1215 |
1.08e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 43.29 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 889 VMNKRLNSLQKELKERNNDIEDMKLEQQ-------NLQGiiKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKknqELE 961
Cdd:PRK04778 22 ILRKRNYKRIDELEERKQELENLPVNDElekvkklNLTG--QSEEKFEEWRQKWDEIVTNSLPDIEEQLFEAEE---LND 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 962 KFKFVldhrieQFKKQIESRENDIKIMQKQIHEMERELEQL---HKEN----TQLKLNITQLQQKLKATDNE----LHKE 1030
Cdd:PRK04778 97 KFRFR------KAKHEINEIESLLDLIEEDIEQILEELQELlesEEKNreevEQLKDLYRELRKSLLANRFSfgpaLDEL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1031 RQKKQNMEALIKRFK---------------MDLHNCVGFIQDY-KKLKAGIRELYTKYVQQL--------EMVE----ME 1082
Cdd:PRK04778 171 EKQLENLEEEFSQFVeltesgdyveareilDQLEEELAALEQImEEIPELLKELQTELPDQLqelkagyrELVEegyhLD 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1083 EVDTDLQ-QEYMRQREYLERNLAAL-----------------------------KKKVVKDQEVHQAAYTRIMQENVSLI 1132
Cdd:PRK04778 251 HLDIEKEiQDLKEQIDENLALLEELdldeaeekneeiqeridqlydilerevkaRKYVEKNSDTLPDFLEHAKEQNKELK 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1133 KEINDLRQELTVAHtqvHDLQSALKLTKKKQAIqdtapsnETLSSPAVLRLNAQK-------ENEKIIEMQLLEIQHLRD 1205
Cdd:PRK04778 331 EEIDRVKQSYTLNE---SELESVRQLEKQLESL-------EKQYDEITERIAEQEiayselqEELEEILKQLEEIEKEQE 400
|
410
....*....|
gi 2024426573 1206 QVQEKGQGLE 1215
Cdd:PRK04778 401 KLSEMLQGLR 410
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
978-1106 |
1.27e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 41.43 E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 978 IESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLkatdNELHKE-------RQKKQNMEALIKRFKMDLHN 1050
Cdd:pfam13851 28 IKSLKEEIAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEV----EELRKQlenyekdKQSLKNLKARLKVLEKELKD 103
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1051 ----CVGFIQDYKKLKAGIRELYTKYVQQLEmvemeevdtDLQQEYMRQREYLERNLAAL 1106
Cdd:pfam13851 104 lkweHEVLEQRFEKVERERDELYDKFEAAIQ---------DVQQKTGLKNLLLEKKLQAL 154
|
|
| PRK11637 |
PRK11637 |
AmiB activator; Provisional |
942-1030 |
1.35e-03 |
|
AmiB activator; Provisional
Pssm-ID: 236942 [Multi-domain] Cd Length: 428 Bit Score: 42.76 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 942 TIQEKEKHIYDLKKKNQELekfkfvldhrIEQFKKQiesrENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLK 1021
Cdd:PRK11637 55 DIAAKEKSVRQQQQQRASL----------LAQLKKQ----EEAISQASRKLRETQNTLNQLNKQIDELNASIAKLEQQQA 120
|
....*....
gi 2024426573 1022 ATDNELHKE 1030
Cdd:PRK11637 121 AQERLLAAQ 129
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
785-939 |
1.54e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 785 KYQELQVDSQRMQEEYEKQLHNLQEsknrtvEELTDYYEEKLNEKSLLLEEAEEdMRQQLQAHEEIKKQIEEDEDREIQD 864
Cdd:PRK12704 32 KIKEAEEEAKRILEEAKKEAEAIKK------EALLEAKEEIHKLRNEFEKELRE-RRNELQKLEKRLLQKEENLDRKLEL 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024426573 865 IKiKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLE---QQNLQGIIKSLEKDISMLNTNIEKR 939
Cdd:PRK12704 105 LE-KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEeakEILLEKVEEEARHEAAVLIKEIEEE 181
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
693-1043 |
1.59e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 42.21 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 693 LDLQIRVKELQIENDYQLRLKDMSCYEKIKElEETFTQELESLKNKHQILQAEKDNQEMQHQLQLSELMNKHAKEMRdle 772
Cdd:pfam13868 11 LNSKLLAAKCNKERDAQIAEKKRIKAEEKEE-ERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEERE--- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 773 sdsNQKLLMENEKYQE---LQVDSQRMQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLL-LEEAEEDMRqqLQAHE 848
Cdd:pfam13868 87 ---QKRQEEYEEKLQEreqMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEkEEEREEDER--ILEYL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 849 EIKKQIEEDEDREIQDIKIKYERW---LIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSL 925
Cdd:pfam13868 162 KEKAEREEEREAEREEIEEEKEREiarLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 926 EKDIsmlntniekrtntiQEKEKhiydLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEmeRELEQLHKE 1005
Cdd:pfam13868 242 EEQI--------------ELKER----RLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHR--RELEKQIEE 301
|
330 340 350
....*....|....*....|....*....|....*...
gi 2024426573 1006 NTQLKlnitqlqqklKATDNELHKERQKKQNMEALIKR 1043
Cdd:pfam13868 302 REEQR----------AAEREEELEEGERLREEEAERRE 329
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
886-1042 |
1.74e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 1.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 886 EIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKhiyDLKKKNQELEKF-- 963
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEA---EIEERREELGERar 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 964 -------------------------------KFVLDH---RIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQL 1009
Cdd:COG3883 94 alyrsggsvsyldvllgsesfsdfldrlsalSKIADAdadLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173
|
170 180 190
....*....|....*....|....*....|...
gi 2024426573 1010 KLNITQLQQKLKATDNELHKERQKKQNMEALIK 1042
Cdd:COG3883 174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELA 206
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
661-901 |
1.80e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 42.65 E-value: 1.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 661 KKGKILKREKEFEYAEEVLIMKSDIEEKsrtilDLQIRVKELQIENDYQLRLKDMscyEKIKELEETFTQELESLKNKHQ 740
Cdd:pfam02463 838 LALELKEEQKLEKLAEEELERLEEEITK-----EELLQELLLKEEELEEQKLKDE---LESKEEKEKEEKKELEEESQKL 909
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 741 ILQAEKDNQEMQHQLQLSELMNKhakemrdlESDSNQKLLMENEKYQELQVDSQRMQEEYEKQlhnlqesknrtveeLTD 820
Cdd:pfam02463 910 NLLEEKENEIEERIKEEAEILLK--------YEEEPEELLLEEADEKEKEENNKEEEEERNKR--------------LLL 967
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 821 YYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKE 900
Cdd:pfam02463 968 AKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAE 1047
|
.
gi 2024426573 901 L 901
Cdd:pfam02463 1048 L 1048
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
940-1142 |
1.87e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 41.04 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 940 TNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFkkqiESRENDikiMQKQIHEMERELEQLHKENTQLKLNITQLQQK 1019
Cdd:pfam15619 17 QNELAELQSKLEELRKENRLLKRLQKRQEKALGKY----EGTESE---LPQLIARHNEEVRVLRERLRRLQEKERDLERK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1020 LKATDNELHKERQKKQNMEALIKRfkmdlhncvgfiqdyKKLkaGIRELYTKYVQQLEmVEMEEVDTDLqQEYMRQREYL 1099
Cdd:pfam15619 90 LKEKEAELLRLRDQLKRLEKLSED---------------KNL--AEREELQKKLEQLE-AKLEDKDEKI-QDLERKLELE 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2024426573 1100 ERN----LAALKKKVVKDQEvhqaaytrimqENVSLIKEINDLRQEL 1142
Cdd:pfam15619 151 NKSfrrqLAAEKKKHKEAQE-----------EVKILQEEIERLQQKL 186
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
624-656 |
1.90e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 36.94 E-value: 1.90e-03
10 20 30
....*....|....*....|....*....|...
gi 2024426573 624 EYQAHAGAITKMSVTNDDLFLLTASEDGSIFFW 656
Cdd:pfam00400 6 TLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
719-1031 |
2.05e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.81 E-value: 2.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 719 EKIKELEETFTQELESLKNKHQILQAEKDNQEmqhqlQLSELMNKHAKEMRDLESdsnqkllmENEKYQELQVDSQRMQE 798
Cdd:COG4372 80 EELEELNEQLQAAQAELAQAQEELESLQEEAE-----ELQEELEELQKERQDLEQ--------QRKQLEAQIAELQSEIA 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 799 EYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEEKE 878
Cdd:COG4372 147 EREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDS 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 879 SNLQLkgeigvmnkRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQ 958
Cdd:COG4372 227 LEAKL---------GLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKL 297
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024426573 959 ELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKER 1031
Cdd:COG4372 298 LALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVADG 370
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
756-1214 |
2.18e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 42.43 E-value: 2.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 756 QLSELMNKHAKEMRDLESDSnqKLLMENEKYQELQVDSQRMQEEY----------------------EKQLHNLQESKNR 813
Cdd:pfam07111 63 QQAELISRQLQELRRLEEEV--RLLRETSLQQKMRLEAQAMELDAlavaekagqaeaeglraalagaEMVRKNLEEGSQR 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 814 TVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKI-KYERWLIEEKESNLQLKGEIGVMnk 892
Cdd:pfam07111 141 ELEEIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEaQKEAELLRKQLSKTQEELEAQVT-- 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 893 RLNSLQK-----------------ELKERNNDIEDMKLEQQNLQGIIKSLEKDIS----MLNTNIEKRTNTIQEKEKHIY 951
Cdd:pfam07111 219 LVESLRKyvgeqvppevhsqtwelERQELLDTMQHLQEDRADLQATVELLQVRVQslthMLALQEEELTRKIQPSDSLEP 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 952 DLKKKNQEL-----EK-FKFV-------LDHR---------IEQFKKQIESRENDIKIMQKQIHE--MERELEQLHKENT 1007
Cdd:pfam07111 299 EFPKKCRSLlnrwrEKvFALMvqlkaqdLEHRdsvkqlrgqVAELQEQVTSQSQEQAILQRALQDkaAEVEVERMSAKGL 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1008 QLKLNITQLQQK-------------------LKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIREL 1068
Cdd:pfam07111 379 QMELSRAQEARRrqqqqtasaeeqlkfvvnaMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHTIKGLMARKVAL 458
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1069 YTKYVQQLEMVEMEE-VDTDLQQEYMRQREYLERNLAALKKKV-VKDQEVHQAAyTRIMQENVSLIKEINDLRQELTVAH 1146
Cdd:pfam07111 459 AQLRQESCPPPPPAPpVDADLSLELEQLREERNRLDAELQLSAhLIQQEVGRAR-EQGEAERQQLSEVAQQLEQELQRAQ 537
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1147 TQV----HDLQSALK---------------LTKKK----QAIQDTAPSNET----LSSPAVLRLN-AQKENEKIIeMQLL 1198
Cdd:pfam07111 538 ESLasvgQQLEVARQgqqesteeaaslrqeLTQQQeiygQALQEKVAEVETrlreQLSDTKRRLNeARREQAKAV-VSLR 616
|
570
....*....|....*.
gi 2024426573 1199 EIQHLRDQVQEKGQGL 1214
Cdd:pfam07111 617 QIQHRATQEKERNQEL 632
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
684-1020 |
2.23e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.19 E-value: 2.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 684 DIEEKSRTILDLQIRVKELQiendyqlrlkdmscyEKIKELEE---TFTQELESLKNKHQILQAEKDNQEmQHQLQLSEL 760
Cdd:pfam07888 60 EKERYKRDREQWERQRRELE---------------SRVAELKEelrQSREKHEELEEKYKELSASSEELS-EEKDALLAQ 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 761 MNKHAKEMRDLESD----SNQKLLMENE----KYQELQVDSQRMQEEYEKQlhNLQESKNRTVEELTDYYEEKLNEKSLL 832
Cdd:pfam07888 124 RAAHEARIRELEEDiktlTQRVLERETElermKERAKKAGAQRKEEEAERK--QLQAKLQQTEEELRSLSKEFQELRNSL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 833 LEEAEEDMRQQ-----LQAHEEIKKQIEEDEDREIQDIKIKYERWLIEEKESNLqLKGEIGVMNKRLNSLQKELK----- 902
Cdd:pfam07888 202 AQRDTQVLQLQdtittLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEG-LGEELSSMAAQRDRTQAELHqarlq 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 903 --ERNNDIEDMKLE--------QQNLQGIIKSLEKDismlNTNIEKRTNTIQEKEKHiydLKKKNQELEKFKFVLDHRIE 972
Cdd:pfam07888 281 aaQLTLQLADASLAlregrarwAQERETLQQSAEAD----KDRIEKLSAELQRLEER---LQEERMEREKLEVELGREKD 353
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 2024426573 973 QFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKL 1020
Cdd:pfam07888 354 CNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRL 401
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
882-1047 |
2.42e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 40.66 E-value: 2.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 882 QLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISmlntniekrtntiqekekhiyDLKKKNQELE 961
Cdd:pfam13851 30 SLKEEIAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLE---------------------NYEKDKQSLK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 962 KFKfvldHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQ--------LQQKLKATDNEL-HKERQ 1032
Cdd:pfam13851 89 NLK----ARLKVLEKELKDLKWEHEVLEQRFEKVERERDELYDKFEAAIQDVQQktglknllLEKKLQALGETLeKKEAQ 164
|
170
....*....|....*
gi 2024426573 1033 kkqnMEALIKRFKMD 1047
Cdd:pfam13851 165 ----LNEVLAAANLD 175
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
696-1137 |
2.62e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 42.37 E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 696 QIRVKELQIENDYQLRLKDmscyekikelEETFTQELESLKNKhqILQAEKDnQEMQHQLQLSELMNKHAKEMRDLEsds 775
Cdd:COG5022 818 CIIKLQKTIKREKKLRETE----------EVEFSLKAEVLIQK--FGRSLKA-KKRFSLLKKETIYLQSAQRVELAE--- 881
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 776 nqkllmenEKYQELQVDSQRMQEEYEKQLHNLQ---ESKNRTVEELTDYYEEKLNEKSLL---LEEAEEDMRQQLQAHEE 849
Cdd:COG5022 882 --------RQLQELKIDVKSISSLKLVNLELESeiiELKKSLSSDLIENLEFKTELIARLkklLNNIDLEEGPSIEYVKL 953
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 850 IKKQIEEDEDREIQDIKIKYERWLIEEKESNLQLKGEIGVMnKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDI 929
Cdd:COG5022 954 PELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSEL-KNFKKELAELSKQYGALQESTKQLKELPVEVAELQSAS 1032
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 930 SMLntniekrtntiqekeKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIEsrenDIKIMQKQIHEMERELEQLHK-ENTQ 1008
Cdd:COG5022 1033 KII---------------SSESTELSILKPLQKLKGLLLLENNQLQARYK----ALKLRRENSLLDDKQLYQLEStENLL 1093
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1009 LKLNITqlqqKLKATDNELHKERQKKQNMEALIKRFkmdlhncvgfiqdykKLKAGIRELYTKYVQQLEMVEMEEVDTDL 1088
Cdd:COG5022 1094 KTINVK----DLEVTNRNLVKPANVLQFIVAQMIKL---------------NLLQEISKFLSQLVNTLEPVFQKLSVLQL 1154
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1089 QQEYMRQREYLERNLAALK-KKVVKDQEVHQAAYTRIMQENVSLIKEIND 1137
Cdd:COG5022 1155 ELDGLFWEANLEALPSPPPfAALSEKRLYQSALYDEKSKLSSSEVNDLKN 1204
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
677-866 |
2.65e-03 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 42.13 E-value: 2.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 677 EVLIMKSDIEEKSRTILDLQIRVKELQIEN-----DYQLRLKDMSCYEKIKELEETFTQELESLKNKHQILQAEKDNQEM 751
Cdd:PRK00448 8 KKLLDQINIPDDLQSEALESAEIEKVVVDKkskkwEFHLKFPNILPIEDFKLFKEKLKQSFSHIADIKVTFSIEVENITF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 752 QHQLQLS--ELMNKHAKEMRDL--ESDSNQKLLMENEKYQeLQVDSQRMQEEYEKQ-LHNLQESKNR----TVEELTDYY 822
Cdd:PRK00448 88 TEELLLDywNEIIEKAKKNSPLfkSLLKKQKVEVEGNKLI-IKVNNEIERDHLKKKhLPKLIKQYEKfgfgILKIDFEID 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2024426573 823 EEKLNEKSLLLEEAEEDMRQQLQAHEEIKK-QIEEDEDREIQDIK 866
Cdd:PRK00448 167 DSKEELEKFEAQKEEEDEKLAKEALEAMKKlEAEKKKQSKNFDPK 211
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
687-861 |
2.94e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.25 E-value: 2.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 687 EKSRTILDLQirvkELQIEN--DYQLRLKDMscyekikelEETFTQELESLKNKHQILQAEKdnQEMQHQLQLSELMNKH 764
Cdd:COG3096 423 EKARALCGLP----DLTPENaeDYLAAFRAK---------EQQATEEVLELEQKLSVADAAR--RQFEKAYELVCKIAGE 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 765 ---------AKEMrdLESDSNQKLLMENE-----KYQELQVDSQRmQEEYEKQLHNLQESKNRTV---EELTDYYEE--- 824
Cdd:COG3096 488 versqawqtAREL--LRRYRSQQALAQRLqqlraQLAELEQRLRQ-QQNAERLLEEFCQRIGQQLdaaEELEELLAElea 564
|
170 180 190
....*....|....*....|....*....|....*..
gi 2024426573 825 KLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDRE 861
Cdd:COG3096 565 QLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARA 601
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
492-531 |
3.35e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 36.52 E-value: 3.35e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 2024426573 492 TFENTNNLKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWN 531
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
802-1014 |
3.45e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 41.16 E-value: 3.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 802 KQLH-NLQESKnrtvEELTDYYEEKLNEKSLLLEE---AEEDMRQ----QLQ-----AHEEIKKQIEEDEDREIQDIKIK 868
Cdd:smart00787 73 KELKkYISEGR----DLFKEIEEETLINNPPLFKEyfsASPDVKLlmdkQFQlvktfARLEAKKMWYEWRMKLLEGLKEG 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 869 YERWLIEEKESNLQLKGEIGVMN-------KRLNSLQKE---LKERNNDIEDMK-LEQQNLQGIIKSLEKDISMLNTNIE 937
Cdd:smart00787 149 LDENLEGLKEDYKLLMKELELLNsikpklrDRKDALEEElrqLKQLEDELEDCDpTELDRAKEKLKKLLQEIMIKVKKLE 228
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024426573 938 KRTNTIQEKEKHIYDLKKKNQELEKfkfvldhRIEQFKKQIEsrendiKIMQKQIHEMERELEQLHKenTQLKLNIT 1014
Cdd:smart00787 229 ELEEELQELESKIEDLTNKKSELNT-------EIAEAEKKLE------QCRGFTFKEIEKLKEQLKL--LQSLTGWK 290
|
|
| F-BAR_PACSIN1 |
cd07680 |
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein ... |
715-848 |
3.68e-03 |
|
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1); F-BAR domains are dimerization modules that bind and bend membranes and are found in proteins involved in membrane dynamics and actin reorganization. Protein kinase C and Casein kinase Substrate in Neurons (PACSIN) proteins, also called Synaptic dynamin-associated proteins (Syndapins), act as regulators of cytoskeletal and membrane dynamics. Vetebrates harbor three isoforms with distinct expression patterns and specific functions. PACSIN 1 or Syndapin I is expressed specifically in the brain and is localized in neurites and synaptic boutons. It binds the brain-specific proteins dynamin I, synaptojanin, synapsin I, and neural Wiskott-Aldrich syndrome protein (nWASP), and functions as a link between the cytoskeletal machinery and synaptic vesicle endocytosis. PACSIN 1 interacts with huntingtin and may be implicated in the neuropathology of Huntington's disease. It contains an N-terminal F-BAR domain and a C-terminal SH3 domain. F-BAR domains form banana-shaped dimers with a positively-charged concave surface that binds to negatively-charged lipid membranes. They can induce membrane deformation in the form of long tubules.
Pssm-ID: 153364 [Multi-domain] Cd Length: 258 Bit Score: 40.80 E-value: 3.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 715 MSCYEKIKELEETFTQELESLKNKHQILQAEKDNQEM---QHQLQLSELMNKHAKEmrDLESDSNQKLlmeNEKYQELQV 791
Cdd:cd07680 108 MGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLackEEKLAMTREANSKAEQ--SVTPEQQKKL---QDKVDKCKQ 182
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 792 DSQRMQEEYEKQLHNLQESKNRTVEELTDYYE--EKLNEKSL-LLEEAEEDMRQQLQAHE 848
Cdd:cd07680 183 DVQKTQEKYEKVLDDVGKTTPQYMENMEQVFEqcQQFEEKRLvFLKEVLLDIKRHLNLAE 242
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
801-1171 |
4.02e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.43 E-value: 4.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 801 EKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEdMRQQLQAHEEIKKQIEEDEDREIQDIKIKY-ERWLIEEKES 879
Cdd:PLN02939 48 KKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVME-LPQKSTSSDDDHNRASMQRDEAIAAIDNEQqTNSKDGEQLS 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 880 NLQLKGEIGV---MNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTntiQEKekhiYDLKKK 956
Cdd:PLN02939 127 DFQLEDLVGMiqnAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAA---QEK----IHVEIL 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 957 NQELEKFKFVLDHRIEqfkkqiesrendikIMQKQIHEMERELEQLHKENTQLKLNITQLQQKL---KATDNELHKERQK 1033
Cdd:PLN02939 200 EEQLEKLRNELLIRGA--------------TEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELievAETEERVFKLEKE 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1034 KQNMEALIKRFKMDLhncVGFIQDYKKLKAGIRELYTKYVQQLEMVeMEEVDTDLQQEYMrqreYLERNlAALKKKVVKD 1113
Cdd:PLN02939 266 RSLLDASLRELESKF---IVAQEDVSKLSPLQYDCWWEKVENLQDL-LDRATNQVEKAAL----VLDQN-QDLRDKVDKL 336
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024426573 1114 QEVHQAAYT--------RIMQENVSLIKEINDLRQELTVAHTQV--------HDLQSALKLTKKKQAIQDTAPS 1171
Cdd:PLN02939 337 EASLKEANVskfssykvELLQQKLKLLEERLQASDHEIHSYIQLyqesikefQDTLSKLKEESKKRSLEHPADD 410
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
936-1045 |
4.09e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.38 E-value: 4.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 936 IEKRTNTIQEKEKHIYDLKKKNQELEKFKfvLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLN--- 1012
Cdd:COG2433 382 LEELIEKELPEEEPEAEREKEHEERELTE--EEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEerr 459
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2024426573 1013 -------ITQLQQKLKATDNELHKERQKKQNMEALIKRFK 1045
Cdd:COG2433 460 eirkdreISRLDREIERLERELEEERERIEELKRKLERLK 499
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
925-1038 |
4.16e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.30 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 925 LEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKfKFVLDHRIEQFKKQIESRENDIKIMQKQIHEME----RELE 1000
Cdd:PRK12704 25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEA-KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEenldRKLE 103
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2024426573 1001 QLHKENTQL---KLNITQLQQKLKATDNELhKERQKKQNME 1038
Cdd:PRK12704 104 LLEKREEELekkEKELEQKQQELEKKEEEL-EELIEEQLQE 143
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
788-957 |
4.56e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 4.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 788 ELQ-VDSQRmqEEYEKQLHNLQESKNRTVEELTDYyEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDED------- 859
Cdd:COG1579 11 DLQeLDSEL--DRLEHRLKELPAELAELEDELAAL-EARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlgnvrn 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 860 -REIQDI-----KIKYERWLIEEKEsnLQLKGEIGVMNKRLNSLQKELKERNNDIEDmklEQQNLQGIIKSLEKDISMLN 933
Cdd:COG1579 88 nKEYEALqkeieSLKRRISDLEDEI--LELMERIEELEEELAELEAELAELEAELEE---KKAELDEELAELEAELEELE 162
|
170 180
....*....|....*....|....
gi 2024426573 934 TNIEKRTNTIQEKEKHIYDLKKKN 957
Cdd:COG1579 163 AEREELAAKIPPELLALYERIRKR 186
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
899-1168 |
4.86e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 41.22 E-value: 4.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 899 KELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQI 978
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELKI 889
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 979 ESRENDI-----KIMQKQIHEMERELEQLHKENTQLKLN-ITQLQQKLKATDNELHKERQK-KQNMEALIKRFKMDLHN- 1050
Cdd:COG5022 890 DVKSISSlklvnLELESEIIELKKSLSSDLIENLEFKTElIARLKKLLNNIDLEEGPSIEYvKLPELNKLHEVESKLKEt 969
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1051 CVGFIQDYKKLKAGIRELYTKyvqqlemveMEEVDT--DLQQEYMRQREYLERNLAALKKKVVKDQEvHQAAYTRIMQE- 1127
Cdd:COG5022 970 SEEYEDLLKKSTILVREGNKA---------NSELKNfkKELAELSKQYGALQESTKQLKELPVEVAE-LQSASKIISSEs 1039
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2024426573 1128 -NVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDT 1168
Cdd:COG5022 1040 tELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDK 1081
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
798-990 |
4.87e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 4.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 798 EEYEKQLHNLQESKNRTVEELTDyyeeklneksllLEEAEEDMRQQLQAHEEIKKQIEEDED-----REIQDIKIKYERW 872
Cdd:COG4913 613 AALEAELAELEEELAEAEERLEA------------LEAELDALQERREALQRLAEYSWDEIDvasaeREIAELEAELERL 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 873 LieekESNLQLKGeigvmnkrlnsLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEK---- 948
Cdd:COG4913 681 D----ASSDDLAA-----------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDlarl 745
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2024426573 949 -HIYDLKKKNQEL------EKFKFVLDHRIEQFKKQIESRENDI-KIMQK 990
Cdd:COG4913 746 eLRALLEERFAAAlgdaveRELRENLEERIDALRARLNRAEEELeRAMRA 795
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
897-1043 |
5.58e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 40.10 E-value: 5.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 897 LQKELKERNNDIEDMKLeqqnlqgiikSLEKDISMLNTNI---EKRTNTIQEKEKHIYDLKKKNQelekfkfvLDHRIEQ 973
Cdd:COG4026 78 FFEELKGMVGHVERMKL----------PLGHDVEYVDVELvrkEIKNAIIRAGLKSLQNIPEYNE--------LREELLE 139
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 974 FKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLkatDNELHKERQKKQNMEALIKR 1043
Cdd:COG4026 140 LKEKIDEIAKEKEKLTKENEELESELEELREEYKKLREENSILEEEF---DNIKSEYSDLKSRFEELLKK 206
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
822-1038 |
5.63e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.18 E-value: 5.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 822 YEEKLNEKSLLLEEAEEDMRQQLqahEEIKKQIEEDEDREIQDikikyerwlieekesnlqlkgeigvmnkRLNSLQKEL 901
Cdd:PRK02224 167 YRERASDARLGVERVLSDQRGSL---DQLKAQIEEKEEKDLHE----------------------------RLNGLESEL 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 902 KERNNDIEdmKLEQQNLQGiIKSLEKDISMLNTNIEKRTnTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESR 981
Cdd:PRK02224 216 AELDEEIE--RYEEQREQA-RETRDEADEVLEEHEERRE-ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEEL 291
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024426573 982 ENDIKIM-------QKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNME 1038
Cdd:PRK02224 292 EEERDDLlaeagldDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE 355
|
|
| ATG17_like |
pfam04108 |
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ... |
862-1108 |
5.76e-03 |
|
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ATG17 and ATG11, conserved across eukaryotes. ATG17 forms a complex with ATG29 and ATG31, critical for both PAS (preautophagosomal structure) formation and autophagy. Together with ATG13, it is required for ATG1 kinase activation. ATG11 is a scaffold protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway during starvation and to recruit ATG proteins to the pre-autophagosome. It is also required for ATG1 kinase activation. In many eukaryotes, ATG11 (the orthologue in mammals is RB1-inducible coiled-coil protein 1 (RB1CC1) and in S. pombe is Taz1-interacting factor 1 (taf1)) is essential for bulk autophagy, except in S.cerevisiae. ATG17 and ATG11 are large similar proteins, both predicted to be almost entirely helical, containing conserved coiled-coil regions and lack obvious functional motifs.
Pssm-ID: 427715 [Multi-domain] Cd Length: 360 Bit Score: 40.45 E-value: 5.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 862 IQDIKIKYERWLIEEKESNLQLKGeIGVMNKRLNSLQKELKER-NNDIEDMKLEQQNLQGIIKSLEKDISML-NTNIEKR 939
Cdd:pfam04108 16 LTDARSLLEELVVLLAKIAFLRRG-LSVQLANLEKVREGLEKVlNELKKDFKQLLKDLDAALERLEETLDKLrNTPVEPA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 940 TNTIQEKEKHIYDlkkknqelekfkFVLDHRIEQ----FKKQIESRENDIKIMQKQIHEMERELEQLHKE-NTQLKLNIT 1014
Cdd:pfam04108 95 LPPGEEKQKTLLD------------FIDEDSVEIlrdaLKELIDELQAAQESLDSDLKRFDDDLRDLQKElESLSSPSES 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1015 QLQQKLKATDNELHkerqkKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLE--MVEMEEVDTDLQQEY 1092
Cdd:pfam04108 163 ISLIPTLLKELESL-----EEEMASLLESLTNHYDQCVTAVKLTEGGRAEMLEVLENDARELDdvVPELQDRLDEMENNY 237
|
250
....*....|....*.
gi 2024426573 1093 MRQREYLERNLAALKK 1108
Cdd:pfam04108 238 ERLQKLLEQKNSLIDE 253
|
|
| MIP-T3_C |
pfam17749 |
Microtubule-binding protein MIP-T3 C-terminal region; This protein, which interacts with both ... |
912-1050 |
5.86e-03 |
|
Microtubule-binding protein MIP-T3 C-terminal region; This protein, which interacts with both microtubules and TRAF3 (tumour necrosis factor receptor-associated factor 3), is conserved from worms to humans. The N-terminal region is the microtubule binding domain and is well-conserved; the C-terminal 100 residues, also well-conserved, constitute the coiled-coil region which binds to TRAF3. The central region of the protein is rich in lysine and glutamic acid and carries KKE motifs which may also be necessary for tubulin-binding, but this region is the least well-conserved.
Pssm-ID: 465481 [Multi-domain] Cd Length: 154 Bit Score: 38.97 E-value: 5.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 912 KLEQQNLQGIIKSLEKDISmLNTNIEKRTNTIQEKEkhIYDLKKKNQELEKfkfvldhRIEQFKKQIESRENDIKIMQkq 991
Cdd:pfam17749 17 KKEYEKGGAEAEPGESDRS-LQESSAKKGRTVSASD--INQLRESIQTLTK-------SANPLGKLLDFIQDDIDSMQ-- 84
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 992 ihemeRELEQLHKENTQlklNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHN 1050
Cdd:pfam17749 85 -----RELQMWRSEYRQ---NAQALQNEQRATDEALQPLYAQLAELEEAIKDQKEKISN 135
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
889-1144 |
6.39e-03 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 40.98 E-value: 6.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 889 VMNKRLNSLQKELKernndIEDMKLEQQNLQGIIKSLEKDIsmlntniEKRTNTIQEKEKHI--YDLKKKNQEL--EKFK 964
Cdd:PRK00448 2 EMQEKFKKLLDQIN-----IPDDLQSEALESAEIEKVVVDK-------KSKKWEFHLKFPNIlpIEDFKLFKEKlkQSFS 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 965 FVLDHRIEqFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQL--KLNITQLQQKLKA-TDNELHKERQKKQNMEALI 1041
Cdd:PRK00448 70 HIADIKVT-FSIEVENITFTEELLLDYWNEIIEKAKKNSPLFKSLlkKQKVEVEGNKLIIkVNNEIERDHLKKKHLPKLI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1042 KrfkmdlhncvgfiqDYKKLKAGIRELYTKYVQQLEMVE-----MEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEV 1116
Cdd:PRK00448 149 K--------------QYEKFGFGILKIDFEIDDSKEELEkfeaqKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDPKEGP 214
|
250 260
....*....|....*....|....*...
gi 2024426573 1117 HQAAYTrIMQENVSLIKEINDLRQELTV 1144
Cdd:PRK00448 215 VQIGKK-IDKEEITPMKEINEEERRVVV 241
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
659-923 |
6.61e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 40.68 E-value: 6.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 659 CSKKGKILKREKEFEYAEEV---LIMKSDIEEKSRTILDLQIRVKELQIENDYQLRLKDMSCYEK-IKELEEtftqELES 734
Cdd:PRK05771 36 LKEELSNERLRKLRSLLTKLseaLDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIEKeIKELEE----EISE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 735 LKNKHQILQAEKDnqemqhqlqlsELmnkhaKEMRDLESDsnqkllMENEKYQE-LQVDSQRMQEEYEKQLhnLQESKNR 813
Cdd:PRK05771 112 LENEIKELEQEIE-----------RL-----EPWGNFDLD------LSLLLGFKyVSVFVGTVPEDKLEEL--KLESDVE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 814 TVEELTDYYEEK----LNEKsllleEAEEDMRQQLQAHEEIKKQIEEDEdrEIQDIkikyerwlIEEKESnlqlkgEIGV 889
Cdd:PRK05771 168 NVEYISTDKGYVyvvvVVLK-----ELSDEVEEELKKLGFERLELEEEG--TPSEL--------IREIKE------ELEE 226
|
250 260 270
....*....|....*....|....*....|....
gi 2024426573 890 MNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIK 923
Cdd:PRK05771 227 IEKERESLLEELKELAKKYLEELLALYEYLEIEL 260
|
|
| TACC_C |
pfam05010 |
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a ... |
936-1063 |
7.23e-03 |
|
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organizing centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1). TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis. Maskin is also found to bind CPEB and elF-4E. Interestingly, the functional homolog (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organization of bipolar spindles.
Pssm-ID: 461517 [Multi-domain] Cd Length: 201 Bit Score: 39.27 E-value: 7.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 936 IEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIkimQKQIHEMERELEQLHKENTQLKLNITQ 1015
Cdd:pfam05010 10 LEKARNEIEEKELEINELKAKYEELRRENLEMRKIVAEFEKTIAQMIEEK---QKQKELEHAEIQKVLEEKDQALADLNS 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2024426573 1016 LQQKLkatdNELHK--ERQK------KQNMEALIKRFKMDLHNCVGFIQDYKKLKA 1063
Cdd:pfam05010 87 VEKSF----SDLFKryEKQKevisgyKKNEESLKKCAQDYLARIKKEEQRYQALKA 138
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
763-1043 |
7.30e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 40.89 E-value: 7.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 763 KHAKEMRDLESD---SNQKLLMENEKYQELQ-VDSQRMQEEYEKQLHNLQES-KNRTVEELTDYYEEKLNE--KSLLLEE 835
Cdd:PTZ00121 1194 RKAEDARKAEAArkaEEERKAEEARKAEDAKkAEAVKKAEEAKKDAEEAKKAeEERNNEEIRKFEEARMAHfaRRQAAIK 1273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 836 AEEDMR-QQLQAHEEIKKQIE---EDEDREIQDIKIKyerwlIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDM 911
Cdd:PTZ00121 1274 AEEARKaDELKKAEEKKKADEakkAEEKKKADEAKKK-----AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA 1348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 912 KLEQQNLQGIIKSLEKDISMlntnIEKRTntiQEKEKHIYDLKKKNQELEKfkfvldhrIEQFKKQIESRENDIKIMQKQ 991
Cdd:PTZ00121 1349 KAEAEAAADEAEAAEEKAEA----AEKKK---EEAKKKADAAKKKAEEKKK--------ADEAKKKAEEDKKKADELKKA 1413
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2024426573 992 IHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKR 1043
Cdd:PTZ00121 1414 AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
908-1143 |
7.44e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 7.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 908 IEDMKLEQQNLQGIIKSLEKDISMLNtNIEKRTNTIQEKEKHIYDLKKKNQELEKfkfvLDHRIEQFKKQIESRenDIKI 987
Cdd:COG4913 213 VREYMLEEPDTFEAADALVEHFDDLE-RAHEALEDAREQIELLEPIRELAERYAA----ARERLAELEYLRAAL--RLWF 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 988 MQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHK-ERQKKQNMEALIKRFKMDlhncvgfIQDYKKLKAGIR 1066
Cdd:COG4913 286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDElEAQIRGNGGDRLEQLERE-------IERLERELEERE 358
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024426573 1067 ELYTKYVQQLEMVEMEEVDTdlQQEYMRQReyleRNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLRQELT 1143
Cdd:COG4913 359 RRRARLEALLAALGLPLPAS--AEEFAALR----AEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIA 429
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
809-1022 |
7.46e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 40.81 E-value: 7.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 809 ESKNRTVEELTDYYEEKLN--EKSLLLEEAEED----MRQQLQAHEEIKkQIEEDEDrEIQDIKIKYERWLIEEK----- 877
Cdd:TIGR01612 1946 EKEPEIYTKIRDSYDTLLDifKKSQDLHKKEQDtlniIFENQQLYEKIQ-ASNELKD-TLSDLKYKKEKILNDVKlllhk 2023
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 878 --ESNlQLKGEIGVMNKRLN-SLQKELKERNNDIEDMKlEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLK 954
Cdd:TIGR01612 2024 fdELN-KLSCDSQNYDTILElSKQDKIKEKIDNYEKEK-EKFGIDFDVKAMEEKFDNDIKDIEKFENNYKHSEKDNHDFS 2101
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024426573 955 KKNQELEKFKfvldhriEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQ-LKLNITQLQQKLKA 1022
Cdd:TIGR01612 2102 EEKDNIIQSK-------KKLKELTEAFNTEIKIIEDKIIEKNDLIDKLIEMRKEcLLFSYATLVETLKS 2163
|
|
| BRLZ |
smart00338 |
basic region leucin zipper; |
989-1029 |
7.56e-03 |
|
basic region leucin zipper;
Pssm-ID: 197664 [Multi-domain] Cd Length: 65 Bit Score: 36.00 E-value: 7.56e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 2024426573 989 QKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHK 1029
Cdd:smart00338 25 KAEIEELERKVEQLEAENERLKKEIERLRRELEKLKSELEE 65
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
823-1005 |
7.90e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 7.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 823 EEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEEKEsnlQLKGEIGvmnkRLNSLQKELK 902
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVA---SAEREIA----ELEAELERLD 681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 903 ERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFV-----LDHRIEQFkkQ 977
Cdd:COG4913 682 ASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLelralLEERFAAA--L 759
|
170 180
....*....|....*....|....*....
gi 2024426573 978 IESRENDI-KIMQKQIHEMERELEQLHKE 1005
Cdd:COG4913 760 GDAVERELrENLEERIDALRARLNRAEEE 788
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
883-1153 |
9.29e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 39.79 E-value: 9.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 883 LKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLntnieKRTNTIQeKEKHIYDLKKKNQELek 962
Cdd:pfam15905 85 LVQERGEQDKRLQALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLEL-----TRVNELL-KAKFSEDGTQKKMSS-- 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 963 fkfvLDHRIEQFKKQIESRENDIKIMQKQiheMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIK 1042
Cdd:pfam15905 157 ----LSMELMKLRNKLEAKMKEVMAKQEG---MEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYIT 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 1043 RfkmdLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMvemeevdtdLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYT 1122
Cdd:pfam15905 230 E----LSCVSEQVEKYKLDIAQLEELLKEKNDEIES---------LKQSLEEKEQELSKQIKDLNEKCKLLESEKEELLR 296
|
250 260 270
....*....|....*....|....*....|.
gi 2024426573 1123 RIMQENVSLIKEINDLRQELTVAHTQVHDLQ 1153
Cdd:pfam15905 297 EYEEKEQTLNAELEELKEKLTLEEQEHQKLQ 327
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
725-861 |
9.88e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.33 E-value: 9.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024426573 725 EETFTQELESLKNKHQILQAEKDNQEMQHQLQLS---ELMNKHAKEM-RDLESD-SNQKLLMEN-----------EKYQE 788
Cdd:PRK04863 451 EQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKiagEVSRSEAWDVaRELLRRlREQRHLAEQlqqlrmrlselEQRLR 530
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024426573 789 LQVDSQRMQEEYEKQlHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEE---DMRQQLqahEEIKKQIEEDEDRE 861
Cdd:PRK04863 531 QQQRAERLLAEFCKR-LGKNLDDEDELEQLQEELEARLESLSESVSEARErrmALRQQL---EQLQARIQRLAARA 602
|
|
| |
