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Conserved domains on  [gi|118109696|ref|XP_428250|]
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homeobox protein Hox-C11 [Gallus gallus]

Protein Classification

DUF3528 and homeodomain domain-containing protein( domain architecture ID 11191843)

DUF3528 and homeodomain domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3528 pfam12045
Protein of unknown function (DUF3528); This family of proteins is functionally uncharacterized. ...
 42-163 9.35e-71

Protein of unknown function (DUF3528); This family of proteins is functionally uncharacterized. This protein is found in eukaryotes. Proteins in this family are typically between 185 to 298 amino acids in length. This protein is found associated with pfam00046.


:

Pssm-ID: 432284  Cd Length: 127  Bit Score: 214.58  E-value: 9.35e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118109696   42 PEFSTVSSFLPQAPSRQISYPYSTNLSQ--PVREVS---YGLDPSSKWHHRSNYASCYSAEDLMHRECIPPST-MTEMLM 115
Cdd:pfam12045   1 PDFSSLPSFLPQTPSCQMTYPYSSNLPQvqPVREVAfrdYALDPSSKWHHRGNYASCYSAEELVHRDCLPPSTtRGEMLF 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 118109696  116 KNESAYSHHHPSSNHPaPTGFYGGMNKNTVLPQGFDRFFENAYCGAEN 163
Cdd:pfam12045  81 KNESVYGHHHHGSSHP-SSNFYSSVGRNGVLPQGFDQFFETAYGSAEG 127
Homeodomain pfam00046
Homeodomain;
229-285 7.24e-26

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 96.80  E-value: 7.24e-26
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 118109696  229 RKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 285
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
 
Name Accession Description Interval E-value
DUF3528 pfam12045
Protein of unknown function (DUF3528); This family of proteins is functionally uncharacterized. ...
 42-163 9.35e-71

Protein of unknown function (DUF3528); This family of proteins is functionally uncharacterized. This protein is found in eukaryotes. Proteins in this family are typically between 185 to 298 amino acids in length. This protein is found associated with pfam00046.


Pssm-ID: 432284  Cd Length: 127  Bit Score: 214.58  E-value: 9.35e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118109696   42 PEFSTVSSFLPQAPSRQISYPYSTNLSQ--PVREVS---YGLDPSSKWHHRSNYASCYSAEDLMHRECIPPST-MTEMLM 115
Cdd:pfam12045   1 PDFSSLPSFLPQTPSCQMTYPYSSNLPQvqPVREVAfrdYALDPSSKWHHRGNYASCYSAEELVHRDCLPPSTtRGEMLF 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 118109696  116 KNESAYSHHHPSSNHPaPTGFYGGMNKNTVLPQGFDRFFENAYCGAEN 163
Cdd:pfam12045  81 KNESVYGHHHHGSSHP-SSNFYSSVGRNGVLPQGFDQFFETAYGSAEG 127
Homeodomain pfam00046
Homeodomain;
229-285 7.24e-26

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 96.80  E-value: 7.24e-26
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 118109696  229 RKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 285
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 228-284 1.53e-22

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 88.08  E-value: 1.53e-22
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 118109696   228 TRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEK 284
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 229-285 3.61e-21

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 84.60  E-value: 3.61e-21
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 118109696 229 RKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 285
Cdd:cd00086    1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKR 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
213-288 5.78e-13

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 65.54  E-value: 5.78e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 118109696 213 VNKEGSKSSNSSAPRTRKKRCpySKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSR 288
Cdd:COG5576   38 EMKLERKQDGSSPPKSKRRRT--TDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRS 111
 
Name Accession Description Interval E-value
DUF3528 pfam12045
Protein of unknown function (DUF3528); This family of proteins is functionally uncharacterized. ...
 42-163 9.35e-71

Protein of unknown function (DUF3528); This family of proteins is functionally uncharacterized. This protein is found in eukaryotes. Proteins in this family are typically between 185 to 298 amino acids in length. This protein is found associated with pfam00046.


Pssm-ID: 432284  Cd Length: 127  Bit Score: 214.58  E-value: 9.35e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118109696   42 PEFSTVSSFLPQAPSRQISYPYSTNLSQ--PVREVS---YGLDPSSKWHHRSNYASCYSAEDLMHRECIPPST-MTEMLM 115
Cdd:pfam12045   1 PDFSSLPSFLPQTPSCQMTYPYSSNLPQvqPVREVAfrdYALDPSSKWHHRGNYASCYSAEELVHRDCLPPSTtRGEMLF 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 118109696  116 KNESAYSHHHPSSNHPaPTGFYGGMNKNTVLPQGFDRFFENAYCGAEN 163
Cdd:pfam12045  81 KNESVYGHHHHGSSHP-SSNFYSSVGRNGVLPQGFDQFFETAYGSAEG 127
Homeodomain pfam00046
Homeodomain;
229-285 7.24e-26

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 96.80  E-value: 7.24e-26
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 118109696  229 RKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 285
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 228-284 1.53e-22

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 88.08  E-value: 1.53e-22
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 118109696   228 TRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEK 284
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 229-285 3.61e-21

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 84.60  E-value: 3.61e-21
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 118109696 229 RKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 285
Cdd:cd00086    1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKR 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
213-288 5.78e-13

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 65.54  E-value: 5.78e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 118109696 213 VNKEGSKSSNSSAPRTRKKRCpySKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSR 288
Cdd:COG5576   38 EMKLERKQDGSSPPKSKRRRT--TDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRS 111
LA-virus_coat pfam09220
L-A virus, major coat protein; Members of this family form the major coat protein of the ...
 42-128 3.16e-03

L-A virus, major coat protein; Members of this family form the major coat protein of the Saccharomyces cerevisiae L-A virus.


Pssm-ID: 401239  Cd Length: 439  Bit Score: 38.84  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118109696   42 PEFSTVSSFLPQapsrqISYPYSTNLSQPVREVSYGLDPSSKWHHRSNYASCYS----AEDLMHRECIPPSTMTEMLMKN 117
Cdd:pfam09220 187 PDWAPFSEFFPS-----IDDPHIDLRPLTEEEAKFVLMMMGEWHPQTNLAIDFEapqlADKFAYRHALPIQDADEWIDAD 261

                          90
                  ....*....|.
gi 118109696  118 ESAYSHHHPSS 128
Cdd:pfam09220 262 GTADQFRLPKS 272
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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