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Conserved domains on  [gi|1489134430|ref|YP_009518751|]
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DNA polymerase III subunit gamma [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

DNA polymerase III subunit gamma/tau( domain architecture ID 11483016)

DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme; gamma and tau subunits are isoforms and either one or both may be present in the holoenzyme; gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex

EC:  2.7.7.7
Gene Ontology:  GO:0009360|GO:0030337|GO:0016887
PubMed:  12940977
SCOP:  8022167

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-430 0e+00

DNA polymerase III subunits gamma and tau; Validated


:

Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 863.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK07994    1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK07994   81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK07994  161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTI 320
Cdd:PRK07994  241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELLHRIAMAQLLPAALDNDMADIELRLRELARTL 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVA----------PTAVMTPTQVP 390
Cdd:PRK07994  321 PPEDVQLYYQTLLIGRKDLPLAPDRRMGVEMTLLRMLAFHPAAPLPEPEVPPQSAAPAAsaqataaptaAVAPPQAPAVP 400
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 1489134430 391 PQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKK 430
Cdd:PRK07994  401 PPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
 
Name Accession Description Interval E-value
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-430 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 863.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK07994    1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK07994   81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK07994  161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTI 320
Cdd:PRK07994  241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELLHRIAMAQLLPAALDNDMADIELRLRELARTL 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVA----------PTAVMTPTQVP 390
Cdd:PRK07994  321 PPEDVQLYYQTLLIGRKDLPLAPDRRMGVEMTLLRMLAFHPAAPLPEPEVPPQSAAPAAsaqataaptaAVAPPQAPAVP 400
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 1489134430 391 PQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKK 430
Cdd:PRK07994  401 PPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-357 0e+00

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 515.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  83 EQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKL 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 163 PVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 243 TLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPP 322
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLAVLESEQEFLKELALKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1489134430 323 TDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRAL 357
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-358 1.15e-169

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 478.92  E-value: 1.15e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVlarkwrPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:COG2812     1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDA-ASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDP 159
Cdd:COG2812    75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 160 QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIAsgdgqvstqavsa 239
Cdd:COG2812   155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIA------------- 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 240 mLGTLD-DDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELAR 318
Cdd:COG2812   222 -FGLLDrRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNEDERERLQELAR 300
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1489134430 319 TIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALA 358
Cdd:COG2812   301 RLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 2.80e-53

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 175.09  E-value: 2.80e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  20 GQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRT 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 100 -KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKAL 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 1489134430 179 D 179
Cdd:pfam13177 161 S 161
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 2.13e-23

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 92.57  E-value: 2.13e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1489134430 178 LDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:cd18137     1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
38-175 3.81e-05

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 43.52  E-value: 3.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   38 HHAYLFSGTRGVGKTSIARLLAKGLNCETGITATpcgvcDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPAR 117
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----IDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1489134430  118 GRFKVYLIDEVHMLSRHSFNALL--------KTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHL 175
Cdd:smart00382  77 LKPDVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRI 142
 
Name Accession Description Interval E-value
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-430 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 863.02  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK07994    1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITATPCGECDNCR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK07994   81 EIEQGRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK07994  161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTI 320
Cdd:PRK07994  241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELLHRIAMAQLLPAALDNDMADIELRLRELARTL 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVA----------PTAVMTPTQVP 390
Cdd:PRK07994  321 PPEDVQLYYQTLLIGRKDLPLAPDRRMGVEMTLLRMLAFHPAAPLPEPEVPPQSAAPAAsaqataaptaAVAPPQAPAVP 400
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 1489134430 391 PQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKK 430
Cdd:PRK07994  401 PPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
1-426 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 574.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14949    1 MSYQVLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQGVTATPCGVCSSCV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14949   81 EIAQGRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14949  161 KLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAAlgndmAAIEL---RMRELA 317
Cdd:PRK14949  241 LGSIDEQHVIALLKALTDADIGVLMQTCAQVLAFGADAQEVLRSLLELLHQITLTQFAPAA-----AQQSLyseQIRAFA 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 318 RTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLP--EPEVPRQSFAPVAPTAVMTPTQVPPQPQS 395
Cdd:PRK14949  316 EQLSPEQVQLYYQILLTGRKDLPHAPDPKSGLEMALLRAVAFVPEKPVKrwQVDDPAEISLPEGQTPSALAAAVQAPHAN 395
                         410       420       430
                  ....*....|....*....|....*....|.
gi 1489134430 396 APQQAPTVPlPETTSQVLAARQQLQRVQGAT 426
Cdd:PRK14949  396 EPQFVNAAP-AEKKTALTEQTTAQQQVQAAN 425
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
1-383 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 537.79  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14969    1 MSYQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14969   81 EIDSGRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14969  161 KIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIElRMRELARTI 320
Cdd:PRK14969  241 LGAIDQDYLFALLEALLAQDGAALLAIADAMEERSLSFDAALQDLAALLHRLAIAQTVPDSIADDLPERD-RLLDLAKRL 319
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1489134430 321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAF--------HPRMPLPEPEVPRQSFAPVAPTAV 383
Cdd:PRK14969  320 SPEDIQLYYQIALHGRRDLGLAPDEYAGFTMTLLRMLAFrpseqdsgAGRAPGAVPGVNRTRAVPTAAPAA 390
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
1-362 0e+00

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 532.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14961    1 MNYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14961   81 EIEKGLCLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14961  161 KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPaaLGND---MAAIELRMRELA 317
Cdd:PRK14961  241 LGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEMLRFLHHISMSQSFP--KIWNtifIKNYKNQIQKIA 318
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1489134430 318 RTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPR 362
Cdd:PRK14961  319 QNNKKTNIQLCYQILLNGRKELKFAPDQKIGVEMTLLRAINAITK 363
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
3-357 0e+00

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 515.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREI 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  83 EQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKL 162
Cdd:TIGR02397  81 NSGSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 163 PVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:TIGR02397 161 PATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 243 TLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPP 322
Cdd:TIGR02397 241 LVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLAVLESEQEFLKELALKLSL 320
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1489134430 323 TDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRAL 357
Cdd:TIGR02397 321 EFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
1-358 1.15e-169

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 478.92  E-value: 1.15e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVlarkwrPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:COG2812     1 MSYQV------PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTGEPCGECESCR 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDA-ASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDP 159
Cdd:COG2812    75 AIAAGSHPDVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 160 QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIAsgdgqvstqavsa 239
Cdd:COG2812   155 QKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQAIA------------- 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 240 mLGTLD-DDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELAR 318
Cdd:COG2812   222 -FGLLDrRELLLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNEDERERLQELAR 300
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1489134430 319 TIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALA 358
Cdd:COG2812   301 RLSPERLLRAIQILLEARRELERNVNPRLALEMLLLRLAR 340
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
1-361 3.40e-166

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 483.83  E-value: 3.40e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK08691    1 MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK08691   81 QIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK08691  161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMReLARTI 320
Cdd:PRK08691  241 IGAVDKQYLYELLTGIINQDGAALLAKAQEMAACAVGFDNALGELAILLQQLALIQAVPSALAHDDPDSDILHR-LAQTI 319
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1489134430 321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHP 361
Cdd:PRK08691  320 SGEQIQLYYQIAVHGKRDLSLAPDEYAGFMMTLLRMLAFAP 360
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
1-417 4.02e-162

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 470.35  E-value: 4.02e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNC-----ETGITATPCGV 75
Cdd:PRK14951    1 MSYLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCqgpdgQGGITATPCGV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  76 CDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLA 155
Cdd:PRK14951   81 CQACRDIDSGRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 156 TTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQ 235
Cdd:PRK14951  161 TTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 236 AVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDM---AAIELR 312
Cdd:PRK14951  241 AVRQMLGSVDRSHVFRLIDALAQGDGRTVVETADELRLNGLSAASTLEEMAAVLQRMAVLQAVPQAAAAATdpeAAEVAR 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 313 mreLARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPR-----------MPLPEPEVPRQSFAPVAPT 381
Cdd:PRK14951  321 ---LAALMPADETQLLYSICLHGRAELGLAPDEYAALTMVLLRLLAFKPAaaaeaaapaekKTPARPEAAAPAAAPVAQA 397
                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 1489134430 382 AVMT-PTQVPPQPQSAPQQAPTVPLPETTSQVLAARQ 417
Cdd:PRK14951  398 AAAPaPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAP 434
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1-382 1.68e-159

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 466.66  E-value: 1.68e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNC-----ETGITATPCGV 75
Cdd:PRK12323    1 MSYQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCtgadgEGGITAQPCGQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  76 CDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLA 155
Cdd:PRK12323   81 CRACTEIDAGRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 156 TTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQ 235
Cdd:PRK12323  161 TTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 236 AVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIElRMRE 315
Cdd:PRK12323  241 AVRGMLGAIDQSYLVRLLDALAAEDGAALLAIADEMAGRSLSFAGALQDLASLLQKIALAQVVPAAVQDDWPEAD-DIRR 319
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1489134430 316 LARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTA 382
Cdd:PRK12323  320 LAGRFDAQEVQLFYQIANLGRSELALAPDEYAGFTMTLLRMLAFRPGQSGGGAGPATAAAAPVAQPA 386
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1-416 1.31e-158

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 468.56  E-value: 1.31e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK07003    1 MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK07003   81 EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK07003  161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMA-AIELrmRELART 319
Cdd:PRK07003  241 LGALDQTYMVRLLDALAAGDGPEILAVADEMALRSLSFSTALQDLASLLHRIAWAQFAPASVLDEWPeAADL--RRFAEL 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 320 IPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMP-------LPEPEVPRQSFAPVAPTAVMTPTQVPPQ 392
Cdd:PRK07003  319 LSPEQVQLFYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEPAVTgggapggGVPARVAGAVPAPGARAAAAVGASAVPA 398
                         410       420
                  ....*....|....*....|....
gi 1489134430 393 PQSAPQQAPTVPLPETTSQVLAAR 416
Cdd:PRK07003  399 VTAVTGAAGAALAPKAAAAAAATR 422
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
3-408 9.99e-152

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 446.80  E-value: 9.99e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREI 82
Cdd:PRK14960    2 YQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  83 EQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKL 162
Cdd:PRK14960   82 NEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKL 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 163 PVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:PRK14960  162 PITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLG 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 243 TLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPP 322
Cdd:PRK14960  242 LIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELGLKYSEEINAKILQLSKLISA 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 323 TDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMP----LPEPEVPR-----------QSFAPVAPTAVMTPT 387
Cdd:PRK14960  322 QDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFRPLAPneilVSEPVQQNgqaevglnsqaQTAQEITPVSAVQPV 401
                         410       420
                  ....*....|....*....|.
gi 1489134430 388 QVPPQPQSAPQQAPTVPLPET 408
Cdd:PRK14960  402 EVISQPAMVEPEPEPEPEPEP 422
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-355 3.25e-151

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 440.46  E-value: 3.25e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK05563    1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDGEPCNECEICK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK05563   81 AITNGSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK05563  161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIEL-RMRELART 319
Cdd:PRK05563  241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEILDESTENDeLFKELSEK 320
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1489134430 320 IPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLR 355
Cdd:PRK05563  321 LDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVK 356
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
1-387 1.44e-140

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 411.43  E-value: 1.44e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14958    1 MAHQVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14958   81 EIDEGRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14958  161 KLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAielRMRELARTI 320
Cdd:PRK14958  241 LGTIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAIIQTVPEALIENDSE---QLRQLAKLL 317
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1489134430 321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSfapvaptAVMTPT 387
Cdd:PRK14958  318 DREDVQLFYQIGLIGQRDLAYSPTPQTGFEMTLLRMLAFYPSAANAIPETESKE-------AVVTPT 377
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
3-367 3.77e-131

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 390.42  E-value: 3.77e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCET-----GITATPCGVCD 77
Cdd:PRK09111   11 YRVLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEGpdgdgGPTIDLCGVGE 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  78 NCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATT 157
Cdd:PRK09111   91 HCQAIMEGRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATT 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 158 DPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAV 237
Cdd:PRK09111  171 EIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEAV 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 238 SAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGN-DMAAIE-LRMRE 315
Cdd:PRK09111  251 RDMLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVLTDLAEFTHLVTRLKIVPDAAEDpSLSEAErTRGAE 330
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1489134430 316 LARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRaLAFHPRMPLPE 367
Cdd:PRK09111  331 FAKKLSMRVLSRLWQMLLKGIEEVQGAPRPLAAAEMVLIR-LAYAADLPTPD 381
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
1-387 1.13e-126

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 378.32  E-value: 1.13e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14965    1 MSYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14965   81 EITEGRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14965  161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAEL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQL--SPAALgNDMAAIEL-RMRELA 317
Cdd:PRK14965  241 LGVVDRRLLLDISAAVFGRDTRALLEIVERVDEFGYNMRQFCQELIDHLRNLVVLRAvgEPGDL-LDLSEAELaELRAQA 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 318 RTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPE------------PEVPRQSFAPVAPTAVMT 385
Cdd:PRK14965  320 AAADAADLQRHLTLLLRAEGEMAHASFPRLVLEMALLKMATLAPGAPVSElldrlealergaPAPPSAAWGAPTPAAPAA 399

                  ..
gi 1489134430 386 PT 387
Cdd:PRK14965  400 PP 401
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
1-362 5.80e-126

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 375.57  E-value: 5.80e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14957    1 MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14957   81 AINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14957  161 KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARtI 320
Cdd:PRK14957  241 LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQSLDAVNDIDVDIINNILAK-I 319
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 1489134430 321 PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPR 362
Cdd:PRK14957  320 SIEQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFQKK 361
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
1-294 8.44e-116

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 347.58  E-value: 8.44e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14953    1 MMYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14953   81 EIDKGSFPDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14953  161 KIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEF 240
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIE----WEALLVEMLGLLHRIAM 294
Cdd:PRK14953  241 LGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNlnkfWKQLEEEIRNILLNKSL 298
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
4-289 8.85e-115

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 346.25  E-value: 8.85e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   4 QVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIE 83
Cdd:PRK08451    2 QALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSSTPCDTCIQCQSAL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  84 QGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
Cdd:PRK08451   82 ENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 164 VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGT 243
Cdd:PRK08451  162 ATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGL 241
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1489134430 244 LDDDQALSLVEAMVEANGERVMALINEaaARGIEWEALLVEMLGLL 289
Cdd:PRK08451  242 LDPSKLEDFFQAILNQDKEKLFELLKE--LEDYEAEMVLDEMMLFL 285
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1-418 7.83e-103

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 317.14  E-value: 7.83e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGI-TATPCGVCDNC 79
Cdd:PRK14950    1 MTVQVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDpKGRPCGTCEMC 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  80 REIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDP 159
Cdd:PRK14950   81 RAIAEGSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 160 QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSA 239
Cdd:PRK14950  161 HKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQS 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 240 MLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELR-MRELAR 318
Cdd:PRK14950  241 LLGISGDEEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQVMLLNSGADRSLLDLTADEKAaLQKVSQ 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 319 TIPPTDI--------QLYYQtlligrkeLPYAPDRRMGVEMTLLRAL--------AFHPRMPLPEP--EVPRQSFAPVAP 380
Cdd:PRK14950  321 IANLEALtkwvkafsQLDFQ--------LRTTSYGQLPLELAVIEALlvpvpapqPAKPTAAAPSPvrPTPAPSTRPKAA 392
                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 1489134430 381 TAVMTPTQVPPQpqsAPQQAPTVPLPETTSQVLAARQQ 418
Cdd:PRK14950  393 AAANIPPKEPVR---ETATPPPVPPRPVAPPVPHTPES 427
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
1-357 1.58e-101

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 313.25  E-value: 1.58e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK06647    1 MSYRGTATKRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK06647   81 SIDNDNSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK06647  161 KLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLV-------EMLGLLHRI---AMVQLSPAALGNDMAAIE 310
Cdd:PRK06647  241 MGLTGDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLdcieffrELLFLKHGIkneAFIGIKAERLPEKLREFD 320
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1489134430 311 LRMRELArtipptdIQLYYQTLligrKELPYAPDRRMGVEMTLLRAL 357
Cdd:PRK06647  321 LSQIERA-------ISVLLETY----RDLQFSVNPRYELEINFSKIL 356
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
1-374 1.28e-100

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 305.66  E-value: 1.28e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGI--------TATP 72
Cdd:PRK14955    1 MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIddadylqeVTEP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  73 CGVCDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKF 152
Cdd:PRK14955   81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 153 LLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIA-----S 227
Cdd:PRK14955  161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAfsvesE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 228 GDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQ-LSPAALGNDM 306
Cdd:PRK14955  241 GEGSIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVVHnLRSTRLVERP 320
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1489134430 307 AAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQS 374
Cdd:PRK14955  321 DAVRERYERDAAKFSPEVIMQMTDLLLQTQKELKFQFEYQFRFELALLKLIEIGHPAPTAAAAPTGGA 388
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
2-291 2.35e-99

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 304.00  E-value: 2.35e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   2 SYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNC-ETGITATPCGVCDNCR 80
Cdd:PRK06305    3 SYQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCqNPTEDQEPCNQCASCK 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK06305   83 EISSGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIH 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK06305  163 KIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKA 242
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEwEALLVEMLGLLHR 291
Cdd:PRK06305  243 LGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVA-PAHFLHDLTLFFR 292
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
1-289 1.86e-97

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 304.19  E-value: 1.86e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNC--ETGITATPCGVCDN 78
Cdd:PRK14948    1 MAYEPLHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNClnSDKPTPEPCGKCEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  79 CREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTD 158
Cdd:PRK14948   81 CRAIAAGNALDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 159 PQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQaIASGDGQVSTQAVS 238
Cdd:PRK14948  161 PQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQ-LSLLPGPITPEAVW 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1489134430 239 AMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLL 289
Cdd:PRK14948  240 DLLGAVPEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAILQGLAAFY 290
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
1-289 2.89e-97

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 306.74  E-value: 2.89e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGIT-ATPCGVCdnc 79
Cdd:PRK07133    3 MKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSHKTDlLEPCQEC--- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  80 reIEQ-GRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTD 158
Cdd:PRK07133   80 --IENvNNSLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTE 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 159 PQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVS 238
Cdd:PRK07133  158 VHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVE 237
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1489134430 239 AMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLL 289
Cdd:PRK07133  238 ELFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLV 288
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
6-367 3.66e-94

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 292.07  E-value: 3.66e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   6 LARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQG 85
Cdd:PRK14964    3 LALKYRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCSNGPTSDPCGTCHNCISIKNS 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  86 RFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVT 165
Cdd:PRK14964   83 NHPDVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVT 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 166 ILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLD 245
Cdd:PRK14964  163 IISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLGCVD 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 246 DDQALSLVEAMVEANGERVMALINEA--AARGIeweALLVEMLGLLHRIAMVQLSP---AALGNDmaaIELRMRELARTI 320
Cdd:PRK14964  243 KHILEDLVEAILLGDAQSALNVFRELcnTSNPV---IILEGMLQIIYEICYFSITKeidFLLGED---LITRIKSLKIGS 316
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1489134430 321 PPTDIQLyYQTLLIGRKELPYAPDRRMGVEMTLLRaLAFHPRMPLPE 367
Cdd:PRK14964  317 TIFLSRL-WQMLLKGIQEVKSSTCVKQAAEMMIIR-LCYLSDLPSPQ 361
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-377 2.80e-93

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 293.89  E-value: 2.80e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK14959    1 MSHASLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14959   81 KVTQGMHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14959  161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGV 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMV-QLSPAALGN-DMAAIELRM-RELA 317
Cdd:PRK14959  241 LGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLrQAGEAALASlDLPEDEARQwLGWA 320
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 318 RTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRaLAFHPRMplpepeVPRQSFAP 377
Cdd:PRK14959  321 KRFEPAHIHACWQMTLEGQRRVLTSLEPAMALELLLLN-LAMLPRL------MPVESLRP 373
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
4-286 6.99e-93

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 288.20  E-value: 6.99e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   4 QVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIE 83
Cdd:PRK14962    2 EALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSID 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  84 QGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
Cdd:PRK14962   82 EGTFMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 164 VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGT 243
Cdd:PRK14962  162 PTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGL 241
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1489134430 244 LDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEML 286
Cdd:PRK14962  242 IPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAI 284
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1-382 8.11e-92

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 289.92  E-value: 8.11e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGI--------TATP 72
Cdd:PRK14954    1 MSYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIddpvylqeVTEP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  73 CGVCDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKF 152
Cdd:PRK14954   81 CGECESCRDFDAGTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 153 LLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIA-----S 227
Cdd:PRK14954  161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAfsvgsE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 228 GDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMV-QLSPAALGNDM 306
Cdd:PRK14954  241 AEKVIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFRNFLVLyNLRSTRLIERP 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 307 AAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAF--------------------HPRMPLP 366
Cdd:PRK14954  321 ESVKERYQQSAGGLTPAAVMQMTDFLMKTQGELKFQFEYQFRFELALLRLIELvrndggvapspagspdvkkkAPEPDLP 400
                         410
                  ....*....|....*.
gi 1489134430 367 EPEVPRQSFAPVAPTA 382
Cdd:PRK14954  401 QPDRHPGPAKPEAPGA 416
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
3-355 1.25e-88

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 281.28  E-value: 1.25e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETgITA--TPCGVCDNCR 80
Cdd:PRK14971    4 YIVSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQN-LTAdgEACNECESCV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK14971   83 AFNEQRSYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKH 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK14971  163 KILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVIEN 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLhRIAMVQLSPAALG--NDMAAIELRMRELAR 318
Cdd:PRK14971  243 LNILDYDYYFRLTDALLAGKVSDSLLLFDEILNKGFDGSHFITGLASHF-RDLLVCKDAATLQllEVGESIRQRYLEQAQ 321
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1489134430 319 TippTDIQLYYQTL-LIGRKELPY--APDRRMGVEMTLLR 355
Cdd:PRK14971  322 K---CPMSFLYRALkLCNQCDLNYraSKNKRLLVELTLIQ 358
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
2-300 3.71e-87

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 273.75  E-value: 3.71e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   2 SYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCRE 81
Cdd:PRK14956    4 THEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  82 IEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQK 161
Cdd:PRK14956   84 ITKGISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 162 LPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAML 241
Cdd:PRK14956  164 IPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMI 243
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 242 GTLDDDQALSLVEAMVE-ANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPA 300
Cdd:PRK14956  244 GYHGIEFLTSFIKSLIDpDNHSKSLEILESLYQEGQDIYKFLWDSIEFTHTLNLIRDSLA 303
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-289 4.19e-87

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 277.11  E-value: 4.19e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   1 MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR 80
Cdd:PRK05896    1 MSEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
Cdd:PRK05896   81 SINTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM 240
Cdd:PRK05896  161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKT 240
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLL 289
Cdd:PRK05896  241 FGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLL 289
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
3-357 5.15e-85

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 269.04  E-value: 5.15e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   3 YQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITAT----PCGVCDN 78
Cdd:PRK06645    8 YIPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALITENttikTCEQCTN 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  79 CREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTD 158
Cdd:PRK06645   88 CISFNNHNHPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTE 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 159 PQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAI---ASGDGQVSTQ 235
Cdd:PRK06645  168 VQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAAsmsAKSDNIISPQ 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 236 AVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRE 315
Cdd:PRK06645  248 VINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESVSDFIAYLNKVKMLPNYSLPIYESFNDRTKS 327
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 1489134430 316 LARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRAL 357
Cdd:PRK06645  328 ILDKISLPHLSILWQIYNKGVGEIKISYNQLTETEMLVIKSI 369
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
6-259 1.63e-84

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 275.33  E-value: 1.63e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   6 LARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQG 85
Cdd:PRK07764    5 LYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTSTPCGECDSCVALAPG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  86 RF--VDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
Cdd:PRK07764   85 GPgsLDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDKVI 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 164 VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIA-SGDGQVSTQAVSAMLG 242
Cdd:PRK07764  165 GTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQLLAgAGPEGVTYERAVALLG 244
                         250
                  ....*....|....*..
gi 1489134430 243 TLDDdqalSLVEAMVEA 259
Cdd:PRK07764  245 VTDS----ALIDEAVDA 257
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
6-427 4.56e-82

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 261.31  E-value: 4.56e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   6 LARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCeTGITATPCGVCDNCREIEQG 85
Cdd:PRK14963    4 LYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNC-SGEDPKPCGECESCLAVRRG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  86 RFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVT 165
Cdd:PRK14963   83 AHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPT 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 166 ILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGdGQVSTQAVSAMLGTLD 245
Cdd:PRK14963  163 ILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLALG-TPVTRKQVEEALGLPP 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 246 DDQALSLVEAMVEanGERVMALINEA-------AARGIEwEALLVEMLGLLH-RIAM-----VQLSPAALGNDMAAIELR 312
Cdd:PRK14963  242 QERLRGIAAALAQ--GDAAEALSGAAqlyrdgfAARTLV-EGLLEAFRAALYaELGLgggprLEGAEPRLLAAMTALDEQ 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 313 MRELARTippTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLP-EPEVPRQSFAPVAPTAVMT------ 385
Cdd:PRK14963  319 MERFARR---SDALSLELALLHALLALGGAPSEGVAAVAPPAPAPADLTQRLNRlEKEVRSLRSAPTAAATAAGaplpdf 395
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 1489134430 386 -PTQVPPQPQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATK 427
Cdd:PRK14963  396 dPRPRGPPAPEPARSAEAPPLVAPAAAPAGLALRWRDVLAALK 438
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
4-357 2.48e-79

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 256.34  E-value: 2.48e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   4 QVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIE 83
Cdd:PRK14952    1 MALYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  84 QGR--FVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQK 161
Cdd:PRK14952   81 PNGpgSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEK 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 162 LPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIA-SGDGQVSTQAVSAM 240
Cdd:PRK14952  161 VLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAgAADTHVTYQRALGL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 241 LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSP--AALGNDMAAIEL--RMREL 316
Cdd:PRK14952  241 LGATDVALIDDAVDALAADDAAALFGAIESVIDAGHDPRRFATDLLERFRDLIVLQAVPdaAARGVVDAPEDVleRMREQ 320
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1489134430 317 ARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRAL 357
Cdd:PRK14952  321 AARIGLATLTRYAEVVQAGLGEMRGATAPRLLLEVVCARLL 361
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
5-302 2.42e-73

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 234.38  E-value: 2.42e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   5 VLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCeTGITATpcgvcdncreiEQ 84
Cdd:PRK14970    6 VSARKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQ-PGYDDP-----------NE 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  85 GRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPV 164
Cdd:PRK14970   74 DFSFNIFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIP 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 165 TILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTL 244
Cdd:PRK14970  154 TILSRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNIL 233
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1489134430 245 DDDQALSLVEAMVEANGERVMALINEAAARGIEWEaLLVEMLGLLHRIAMVQLSPAAL 302
Cdd:PRK14970  234 DYDTYINVTDLILENKIPELLLAFNEILRKGFDGH-HFIAGLASHFRDLMVSKTPATI 290
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-179 2.80e-53

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 175.09  E-value: 2.80e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  20 GQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRT 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 100 -KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKAL 178
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 1489134430 179 D 179
Cdd:pfam13177 161 S 161
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
21-318 5.59e-51

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 173.62  E-value: 5.59e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  21 QEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDnCREIEQGRFVDLIEI--DAASR 98
Cdd:COG0470     1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELnpEEKSD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  99 T-KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKA 177
Cdd:COG0470    80 QiGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 178 LDVEQIRHQLEhilnEEHIAHEprALQLLARAAEGSLRDALSLTDQAiasgdgQVSTQAVSAMLGTLDDDQALSLVEamv 257
Cdd:COG0470   160 PSEEEALAWLR----EEGVDED--ALEAILRLAGGDPRAAINLLQAL------AGRKELLEDLAALLSRDRALELLD--- 224
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1489134430 258 eangervmALINEAAARGIEWeallveMLGLLHRIAMVQLSPAALGNDMAAIELRMRELAR 318
Cdd:COG0470   225 --------ALLKAEALELLDW------LLKWLLDNLPLEYAGEDLARAYEALSEADRRLGR 271
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
25-217 2.12e-50

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 168.57  E-value: 2.12e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  25 LTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDA-ASRTKVED 103
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPeGQSIKVDQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 104 TRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQI 183
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEAL 160
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1489134430 184 RHQLEHILNEEHiaheprALQLLARAAEGSLRDA 217
Cdd:TIGR00678 161 LQWLIRQGISEE------AAELLLALAGGSPGRA 188
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
21-220 1.90e-32

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 125.42  E-value: 1.90e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  21 QEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEI--DAASr 98
Cdd:PRK08058   11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVapDGQS- 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  99 TKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEP-PEHVKFLLaTTDPQKLPVTILSRCLQFHLKA 177
Cdd:PRK08058   90 IKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPsGGTTAILL-TENKHQILPTILSRCQVVEFRP 168
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1489134430 178 LDVEQIRHQLEhilnEEHIahePRALQLLARAAEGSLRDALSL 220
Cdd:PRK08058  169 LPPESLIQRLQ----EEGI---SESLATLLAGLTNSVEEALAL 204
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
9-315 5.21e-30

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 118.94  E-value: 5.21e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHaYLFSGTRGVGKTSIARLLAKGL---NCETGITATPcgVCD----NCRE 81
Cdd:PRK12402    8 KYRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARELygdPWENNFTEFN--VADffdqGKKY 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  82 IEQG-RFVDLIEIDAASRTKVedtRDLLDNV-----QYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLA 155
Cdd:PRK12402   85 LVEDpRFAHFLGTDKRIRSSK---IDNFKHVlkeyaSYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 156 TTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALsLTDQAIASGDGQVSTQ 235
Cdd:PRK12402  162 TRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAI-LTLQTAALAAGEITME 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 236 AVSAMLGTLD-DDQALSLVEAMVEANGERVMALIneaaargiewEALLV-------EMLGLLHRIAMVQLSP---AALGN 304
Cdd:PRK12402  241 AAYEALGDVGtDEVIESLLDAAEAGDFTDARKTL----------DDLLIdeglsggEVLEELLRVARSRYRGdnlARLHR 310
                         330
                  ....*....|.
gi 1489134430 305 DMAAIELRMRE 315
Cdd:PRK12402  311 LAADADARLTD 321
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
36-182 6.44e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 112.66  E-value: 6.44e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  36 RIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITA-TPCGVCDNCREIEQGRFVDLIEIDAASR----------TKVEDT 104
Cdd:PRK08699   19 RRPNAWLFAGKKGIGKTAFARFAAQALLCETPAPGhKPCGECMSCHLFGQGSHPDFYEITPLSDepengrkllqIKIDAV 98
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1489134430 105 RDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQ 182
Cdd:PRK08699   99 REIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSHEE 176
DNA_pol3_gamma3 pfam12169
DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, ...
232-367 2.43e-27

DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432379 [Multi-domain]  Cd Length: 143  Bit Score: 106.20  E-value: 2.43e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 232 VSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSP-AALGNDMAAIE 310
Cdd:pfam12169   1 VTAAQVRDMLGLADRGRVLDLLEALLEGDAAAALAELRDQYDAGADPVVVLRDLLELIHNLTRLKVAPdAADDLLLPEEE 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1489134430 311 L-RMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRaLAFHPRMPLPE 367
Cdd:pfam12169  81 RaRLAELAEKLSPEVLHRLWQMLLKGIEEVPNAPDPRQAAEMVLLR-LAYAASLPPPE 137
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
15-282 7.66e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 105.38  E-value: 7.66e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  15 FADVVGQEHVLTAL------ANGLSLGRIH---HAYLFSGTRGVGKTSIARLLAKGLNCeTGITATPCGVCDNCREIEQG 85
Cdd:PRK07940    4 WDDLVGQEAVVAELraaaraARADVAAAGSgmtHAWLFTGPPGSGRSVAARAFAAALQC-TDPDEPGCGECRACRTVLAG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  86 RFVDLIEIDAASRT-KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPV 164
Cdd:PRK07940   83 THPDVRVVAPEGLSiGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLP 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 165 TILSRCLQFHLKALDVEQIRHQLehiLNEEHIAHEpRAlQLLARAAEGSLRDA--LSLTDQAIASGDgqvstQAVSAMLG 242
Cdd:PRK07940  163 TIRSRCRHVALRTPSVEAVAEVL---VRRDGVDPE-TA-RRAARASQGHIGRArrLATDEEARARRA-----EVLNLALR 232
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1489134430 243 TLDDDQALSLVEAMVEANGERVMALINEAAARgiEWEALL 282
Cdd:PRK07940  233 LARVSDAVAAAEELVKAAEAEAKALTAERDEA--ETEELR 270
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
6-228 7.70e-25

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 105.55  E-value: 7.70e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   6 LARKWRPQTFADVVGQEHVL---TALANGLSLGRIHHAyLFSGTRGVGKTSIARLLAKGLNCEtgitatpcgvcdncrei 82
Cdd:PRK13342    2 LAERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGATDAP----------------- 63
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  83 eqgrfvdLIEIDAASrTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEppEHVKFLLATT-DPQ- 160
Cdd:PRK13342   64 -------FEALSAVT-SGVKDLREVIEEARQRRSAGRRTILFIDEIHRFNKAQQDALLPHVED--GTITLIGATTeNPSf 133
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1489134430 161 KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEE---HIAHEPRALQLLARAAEGSLRDALSLTDQAIASG 228
Cdd:PRK13342  134 EVNPALLSRAQVFELKPLSEEDIEQLLKRALEDKergLVELDDEALDALARLANGDARRALNLLELAALGV 204
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
178-242 2.13e-23

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 92.57  E-value: 2.13e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1489134430 178 LDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLG 242
Cdd:cd18137     1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
35-223 9.44e-23

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 98.24  E-value: 9.44e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  35 GRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDL--IEIDAASRT-KVEDTRDLLDNV 111
Cdd:PRK05707   19 GRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNfvLEPEEADKTiKVDQVRELVSFV 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 112 QYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHIL 191
Cdd:PRK05707   99 VQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEESLQWLQQAL 178
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1489134430 192 NEEhiaHEPRALQLLARAAEGSLRdALSLTDQ 223
Cdd:PRK05707  179 PES---DERERIELLTLAGGSPLR-ALQLHEQ 206
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
12-275 1.19e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 92.41  E-value: 1.19e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  12 PQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCD------NCREIEQG 85
Cdd:PRK09112   19 PSENTRLFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHILSHPDPAEAPETLADpdpaspVWRQIAQG 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  86 ---------RFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLAT 156
Cdd:PRK09112   99 ahpnllhitRPFDEKTGKFKTAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILIS 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 157 TDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRalQLLARAAEGSLRDALSLtdqaIASGDGQVStQA 236
Cdd:PRK09112  179 HSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSSQGSDGEIT--EALLQRSKGSVRKALLL----LNYGGLEII-AT 251
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1489134430 237 VSAMLGTLDDD--------QALSLVEAMV------EANGERVMALINEAAARG 275
Cdd:PRK09112  252 IDQLLAGSGPDarkahklaDALSGRESEVqfdffrDHLLDRIMAEARRAAEAG 304
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
11-267 9.11e-20

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 90.09  E-value: 9.11e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  11 RPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTS----IARLLAKGLNCETGITATPCGVCD------NCR 80
Cdd:PRK07471   14 HPRETTALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATlayrMARFLLATPPPGGDGAVPPPTSLAidpdhpVAR 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  81 EIEQGRFVDLIEI-----DAASRTK----VEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVK 151
Cdd:PRK07471   94 RIAAGAHGGLLTLerswnEKGKRLRtvitVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSL 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 152 FLLATTDPQKLPVTILSRCLQFHLKALDVEqirhQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLtdqaiASGDGQ 231
Cdd:PRK07471  174 FLLVSHAPARLLPTIRSRCRKLRLRPLAPE----DVIDALAAAGPDLPDDPRAALAALAEGSVGRALRL-----AGGDGL 244
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1489134430 232 VSTQAVSAMLGTL---DDDQALSLVEAMVEANGERVMAL 267
Cdd:PRK07471  245 ALYRRLTALLDTLprlDRRALHALADAAAGRDRAARFAL 283
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
15-214 3.28e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 87.65  E-value: 3.28e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  15 FADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLncetgITATPCGVCDNCReIEQGRFVDLIEI- 93
Cdd:PRK07399    3 FANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGL-----LSQGSPSKNIRRR-LEEGNHPDLLWVe 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  94 -------------DAASRT---------KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEpPEHVK 151
Cdd:PRK07399   77 ptyqhqgklitasEAEEAGlkrkappqiRLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEE-PGNGT 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1489134430 152 FLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSL 214
Cdd:PRK07399  156 LILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALAQGSPGAA 218
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
178-241 5.32e-19

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 80.59  E-value: 5.32e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1489134430 178 LDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGD-GQVSTQAVSAML 241
Cdd:cd18133     1 LDQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDdGKISLDRVYQAV 65
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
32-188 5.41e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 86.61  E-value: 5.41e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  32 LSLGRIHHAYLFSGtrGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRT-KVEDTRDLLDN 110
Cdd:PRK07276   18 LEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQGQViKTDTIRELVKN 95
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1489134430 111 VQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKAlDVEQIRHQLE 188
Cdd:PRK07276   96 FSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFPK-NEAYLIQLLE 172
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
36-175 8.41e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 87.12  E-value: 8.41e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  36 RIHHAYLFSGTRGVGKTSIARLLAKGLNCETGIT-ATPCGVCDNCREIEQGRFVD--------------LIEIDAA---- 96
Cdd:PRK06964   19 RLPHALLLHGQAGIGKLDFAQHLAQGLLCETPQPdGEPCGTCAACNWFAQGNHPDyrivrpealaaeapGAADEAKeada 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  97 ------SRT-----KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVT 165
Cdd:PRK06964   99 deggkkTKApskeiKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPT 178
                         170
                  ....*....|
gi 1489134430 166 ILSRCLQFHL 175
Cdd:PRK06964  179 ILSRCRQFPM 188
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
15-194 1.20e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 83.16  E-value: 1.20e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  15 FADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLA-KGLNcetgitatpcgvcdncrEIEQGRFVDLIE- 92
Cdd:PRK05564    3 FHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIAlKILG-----------------KSQQREYVDIIEf 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  93 -IDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCL 171
Cdd:PRK05564   66 kPINKKSIGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQ 145
                         170       180
                  ....*....|....*....|....*.
gi 1489134430 172 QFHLKALDVEQIRHQLE---HILNEE 194
Cdd:PRK05564  146 IYKLNRLSKEEIEKFISykyNDIKEE 171
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
6-242 1.50e-17

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 84.34  E-value: 1.50e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   6 LARKWRPQTFADVVGQEHVL---TALANGLSLGRIHHAYLFsGTRGVGKTSIARLLAKGLNCEtgitatpcgvcdncrei 82
Cdd:COG2256    15 LAERMRPRTLDEVVGQEHLLgpgKPLRRAIEAGRLSSMILW-GPPGTGKTTLARLIANATDAE----------------- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  83 eqgrFVDLieidAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHmlsRhsFN-----ALLKTLEEppEHVKFLLATT 157
Cdd:COG2256    77 ----FVAL----SAVTSGVKDIREVIEEARERRAYGRRTILFVDEIH---R--FNkaqqdALLPHVED--GTITLIGATT 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 158 D--------PqklpvtILSRCLQFHLKALDVEQIR-------HQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTD 222
Cdd:COG2256   142 EnpsfevnsA------LLSRCRVFVLKPLSEEDLEqlleralADDERGLGGYKLELDDEALEALARLADGDARRALNALE 215
                         250       260
                  ....*....|....*....|....
gi 1489134430 223 QAIAS----GDGQVSTQAVSAMLG 242
Cdd:COG2256   216 LAVLSappdGVIEITLELVEEALQ 239
rfc PRK00440
replication factor C small subunit; Reviewed
9-243 4.35e-17

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 81.46  E-value: 4.35e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHaYLFSGTRGVGKTSIARLLAKGLNCETGItatpcgvcDNCREI----EQ 84
Cdd:PRK00440   10 KYRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALARELYGEDWR--------ENFLELnasdER 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  85 GrfVDLIeidaasRTKVED---TRDLLDnvqyAPargrFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQK 161
Cdd:PRK00440   81 G--IDVI------RNKIKEfarTAPVGG----AP----FKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSK 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 162 LPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTdQAIASGDGQVSTQAVSAML 241
Cdd:PRK00440  145 IIDPIQSRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINAL-QAAAATGKEVTEEAVYKIT 223

                  ..
gi 1489134430 242 GT 243
Cdd:PRK00440  224 GT 225
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
35-170 4.69e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 81.70  E-value: 4.69e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  35 GRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIdAASRTK---VEDTRDLLDNV 111
Cdd:PRK06871   21 GLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHIL-EPIDNKdigVDQVREINEKV 99
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1489134430 112 QYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC 170
Cdd:PRK06871  100 SQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRC 158
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
35-249 4.84e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 81.65  E-value: 4.84e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  35 GRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVD---LIEIDAASRTKVEDTRDLLDNV 111
Cdd:PRK07993   21 GRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDyytLTPEKGKSSLGVDAVREVTEKL 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 112 qYAPAR-GRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHi 190
Cdd:PRK07993  101 -YEHARlGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCRLHYLAPPPEQYALTWLSR- 178
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1489134430 191 lneeHIAHEPRALQLLARAAEGSLRDALSL--TDQ-AIASGDGQVSTQAVS-----AMLGTLDDDQA 249
Cdd:PRK07993  179 ----EVTMSQDALLAALRLSAGAPGAALALlqPERwQQREALCQALAYALPsgdwlSLLPALNHEQA 241
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
28-251 2.59e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 76.38  E-value: 2.59e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  28 LANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETgITATPCGVCDNCREIEQGRFVDLIEIDAASRTK---VEDT 104
Cdd:PRK06090   15 WKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQN-YQSEACGFCHSCELMQSGNHPDLHVIKPEKEGKsitVEQI 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 105 RDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIR 184
Cdd:PRK06090   94 RQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAM 173
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1489134430 185 HQlehiLNEEHIAHEPRALQL--------LARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDDQALS 251
Cdd:PRK06090  174 QW----LKGQGITVPAYALKLnmgsplktLAMMKEGGLEKYHKLERQLVDALSGPVSDQLKCASLIAADPLTHLS 244
PRK04195 PRK04195
replication factor C large subunit; Provisional
9-256 1.20e-14

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 75.73  E-value: 1.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   9 KWRPQTFADVVGQEHVLTAL---ANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNcetgitatpcgvcdncreieqg 85
Cdd:PRK04195    7 KYRPKTLSDVVGNEKAKEQLrewIESWLKGKPKKALLLYGPPGVGKTSLAHALANDYG---------------------- 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  86 rfVDLIEIDAA-SRTKvED----------TRDLLdnvqyapARGRfKVYLIDEVHMLS----RHSFNALLKTLEEPPEHV 150
Cdd:PRK04195   65 --WEVIELNASdQRTA-DViervageaatSGSLF-------GARR-KLILLDEVDGIHgnedRGGARAILELIKKAKQPI 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 151 kfLLATTDPQKLP-VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAlsLTD-QAIASG 228
Cdd:PRK04195  134 --ILTANDPYDPSlRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSA--INDlQAIAEG 209
                         250       260
                  ....*....|....*....|....*...
gi 1489134430 229 DGQVSTQAVSAMlgtLDDDQALSLVEAM 256
Cdd:PRK04195  210 YGKLTLEDVKTL---GRRDREESIFDAL 234
44 PHA02544
clamp loader, small subunit; Provisional
9-203 1.79e-13

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 70.79  E-value: 1.79e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLakglncetgitatpcgvcdnCREIEqgrfV 88
Cdd:PHA02544   14 KYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKAL--------------------CNEVG----A 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  89 DLIEIDAASrTKVEDTRDLLDNvqYAPA---RGRFKVYLIDEVHMLSRHSFNALLKTL-EEPPEHVKFLLATTDPQKLPV 164
Cdd:PHA02544   70 EVLFVNGSD-CRIDFVRNRLTR--FASTvslTGGGKVIIIDEFDRLGLADAQRHLRSFmEAYSKNCSFIITANNKNGIIE 146
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1489134430 165 TILSRCLQFHL-KALDVEQIR------HQLEHILNEEHIAHEPRAL 203
Cdd:PHA02544  147 PLRSRCRVIDFgVPTKEEQIEmmkqmiVRCKGILEAEGVEVDMKVL 192
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
101-175 3.66e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 69.44  E-value: 3.66e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1489134430 101 VEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHL 175
Cdd:PRK05917   77 IETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSIHI 151
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
72-173 1.72e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 64.08  E-value: 1.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  72 PCGVCDNCREIEQGRFVDLIEI-DAASRTKVEDTRDLLD--NVQYAPARGRfKVYLIDEVHMLSRHSFNALLKTLEEPPE 148
Cdd:PRK05818   39 FCKTCESCLKILNGKYNDFYLIfDQKNPIKKEDALSIINklNRPSVESNGK-KIYIIYGIEKLNKQSANSLLKLIEEPPK 117
                          90       100
                  ....*....|....*....|....*
gi 1489134430 149 HVKFLLATTDPQKLPVTILSRCLQF 173
Cdd:PRK05818  118 NTYGIFTTRNENNILNTILSRCVQY 142
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-170 2.07e-11

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 61.78  E-value: 2.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  19 VGQEHVLTALANGLSLGRIHHaYLFSGTRGVGKTSIARLLAKGLNcetgitatpcgvcdncreieqGRFVDLIEIDAASR 98
Cdd:cd00009     1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELF---------------------RPGAPFLYLNASDL 58
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  99 TKVEDTRDLLDNVQYAPARGRFK-----VYLIDEVHMLSRHSFNALLKTLEE------PPEHVKFLLATTDP--QKLPVT 165
Cdd:cd00009    59 LEGLVVAELFGHFLVRLLFELAEkakpgVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNRPllGDLDRA 138

                  ....*
gi 1489134430 166 ILSRC 170
Cdd:cd00009   139 LYDRL 143
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
32-175 2.42e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 61.51  E-value: 2.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  32 LSLGRIHHAYLFSGTRGVGKTSIARLLAKGLnceTGITATPcGVCDNCRE-IEQGRFVDLIEID-AASRTK--------V 101
Cdd:PRK08769   20 LDAGRLGHGLLICGPEGLGKRAVALALAEHV---LASGPDP-AAAQRTRQlIAAGTHPDLQLVSfIPNRTGdklrteivI 95
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1489134430 102 EDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC--LQFHL 175
Cdd:PRK08769   96 EQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCqrLEFKL 171
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
28-193 3.88e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 60.51  E-value: 3.88e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  28 LANGLSLGRIHHAYLFSGT-RGVGKTSIARLLAKGLNCETGitatpcGVCDNCREIEqGRFVDLIEIDaasrTKVEDTRD 106
Cdd:PRK07132    8 LDNSATQNKISHSFLLKSNyNEDIDEKILYFLNKFNNLQIT------NLNEQELPAN-IILFDIFDKD----LSKSEFLS 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 107 LLDNVQYAP-ARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIrh 185
Cdd:PRK07132   77 AINKLYFSSfVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKI-- 154

                  ....*...
gi 1489134430 186 qLEHILNE 193
Cdd:PRK07132  155 -LAKLLSK 161
PRK13341 PRK13341
AAA family ATPase;
6-232 8.50e-10

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 60.84  E-value: 8.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   6 LARKWRPQTFADVVGQEHVLTA---LANGLSLGRIHHAyLFSGTRGVGKTSIARLLAKGLNCE-TGITATPCGVCDNCRE 81
Cdd:PRK13341   18 LADRLRPRTLEEFVGQDHILGEgrlLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANHTRAHfSSLNAVLAGVKDLRAE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  82 IEQGRfvdlieidaaSRTKVEDTRDLLdnvqyapargrfkvyLIDEVHMLSRHSFNALLKTLEEPPehVKFLLATTDPQK 161
Cdd:PRK13341   97 VDRAK----------ERLERHGKRTIL---------------FIDEVHRFNKAQQDALLPWVENGT--ITLIGATTENPY 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 162 LPV--TILSRCLQFHLKALDVEQIRHQLEHILNEEH-------IAHEPRALQLLARAAEG---SLRDALSLTDQA-IASG 228
Cdd:PRK13341  150 FEVnkALVSRSRLFRLKSLSDEDLHQLLKRALQDKErgygdrkVDLEPEAEKHLVDVANGdarSLLNALELAVEStPPDE 229

                  ....
gi 1489134430 229 DGQV 232
Cdd:PRK13341  230 DGLI 233
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
41-170 2.60e-09

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 54.91  E-value: 2.60e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  41 YLFSGTRGVGKTSIARLLAKglncETGItatpcgvcdNCREIEQGRFVDLIEIDAASRtkvedTRDLLDNVQyapaRGRF 120
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAK----ELGA---------PFIEISGSELVSKYVGESEKR-----LRELFEAAK----KLAP 58
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1489134430 121 KVYLIDEVHMLSRHSF-----------NALLKTLEEP---PEHVKFLLATTDPQKLPVTILSRC 170
Cdd:pfam00004  59 CVIFIDEIDALAGSRGsggdsesrrvvNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRF 122
PLN03025 PLN03025
replication factor C subunit; Provisional
9-237 5.30e-09

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 57.43  E-value: 5.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHaYLFSGTRGVGKTSIARLLAKGLncetgitatpcgVCDNCREIeqgrfv 88
Cdd:PLN03025    6 KYRPTKLDDIVGNEDAVSRLQVIARDGNMPN-LILSGPPGTGKTTSILALAHEL------------LGPNYKEA------ 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  89 dLIEIDAASRTKVEDTRDLL-----DNVQYAParGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLP 163
Cdd:PLN03025   67 -VLELNASDDRGIDVVRNKIkmfaqKKVTLPP--GRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKII 143
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1489134430 164 VTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSlTDQAIASGDGQVSTQAV 237
Cdd:PLN03025  144 EPIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALN-NLQATHSGFGFVNQENV 216
PRK04132 PRK04132
replication factor C small subunit; Provisional
120-237 1.37e-08

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 57.16  E-value: 1.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 120 FKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHE 199
Cdd:PRK04132  631 FKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELT 710
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1489134430 200 PRALQLLARAAEGSLRDALSLTdQAIASGDGQVSTQAV 237
Cdd:PRK04132  711 EEGLQAILYIAEGDMRRAINIL-QAAAALDDKITDENV 747
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
137-223 5.41e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 50.03  E-value: 5.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 137 NALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC-------------LQFHLKALDVEQIRHQLEHILNEEHIAHEpRAL 203
Cdd:PRK08485   72 NALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLiiekrkqkkpvkpLDLDLKKLDLKDIYEFLKELEKENKLSKE-ELK 150
                          90       100
                  ....*....|....*....|
gi 1489134430 204 QLLARAAEGSLRDALSLTDQ 223
Cdd:PRK08485  151 ELIESLLKECVKYKIPLNEE 170
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
121-313 9.62e-07

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 50.25  E-value: 9.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 121 KVYLIDEVHMLSR--HSFNALLKTLEEPPEHVKFLLATTDP---QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEH 195
Cdd:COG1466    64 RLVIVRNAEFLKKpgEGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKAAG 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 196 IAHEPRALQLLARAAEGSLRDALSLTDQ--AIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAA 273
Cdd:COG1466   144 LRIDPDAAQLLAERVGGDLLALAQELEKlaLYAGDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRRLLA 223
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1489134430 274 RGIEwealLVEMLGLLHR----IAMVQLSPAALGNDMAAI-ELRM 313
Cdd:COG1466   224 EGEE----PVLILAALARqfrlLLQVKALLAQGKSLAEIAkELGV 264
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
178-239 5.62e-06

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 43.67  E-value: 5.62e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1489134430 178 LDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTdQAIASGDGQVSTQAVSA 239
Cdd:cd18140     1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDL-QAAAAGGGVITEEDVYE 61
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
92-177 1.13e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 46.76  E-value: 1.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  92 EIDAASRTK---VEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQKLPVTILS 168
Cdd:PRK06581   59 ETSATSNAKnisIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRS 138

                  ....*....
gi 1489134430 169 RCLQFHLKA 177
Cdd:PRK06581  139 RCFKINVRS 147
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
6-241 2.60e-05

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 46.06  E-value: 2.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   6 LARKWRPQTFADVVGQEHVLTAL---------------ANGLSLGRihhAYLFSGTRGVGKTSIARLLAKGLNcetgita 70
Cdd:COG0464   147 ELLELREAILDDLGGLEEVKEELrelvalplkrpelreEYGLPPPR---GLLLYGPPGTGKTLLARALAGELG------- 216
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  71 tpcgvcdncreieqgrfVDLIEIDAAS-RTK-VEDT----RDLLDNV-QYAPArgrfkVYLIDEVHML--------SRHS 135
Cdd:COG0464   217 -----------------LPLIEVDLSDlVSKyVGETeknlREVFDKArGLAPC-----VLFIDEADALagkrgevgDGVG 274
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 136 ---FNALLKTLEEPPEHVKFLLATTDPQKLPVTILSRC-LQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAE 211
Cdd:COG0464   275 rrvVNTLLTEMEELRSDVVVIAATNRPDLLDPALLRRFdEIIFFPLPDAEERLEIFRIHLRKRPLDEDVDLEELAEATEG 354
                         250       260       270
                  ....*....|....*....|....*....|....
gi 1489134430 212 GSLRD----ALSLTDQAIASGDGQVSTQAVSAML 241
Cdd:COG0464   355 LSGADirnvVRRAALQALRLGREPVTTEDLLEAL 388
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
38-175 3.81e-05

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 43.52  E-value: 3.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430   38 HHAYLFSGTRGVGKTSIARLLAKGLNCETGITATpcgvcDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPAR 117
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----IDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARK 76
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1489134430  118 GRFKVYLIDEVHMLSRHSFNALL--------KTLEEPPEHVKFLLATTDPQKLPVTILSRCLQFHL 175
Cdd:smart00382  77 LKPDVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRI 142
PRK04132 PRK04132
replication factor C small subunit; Provisional
9-61 8.66e-05

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 44.83  E-value: 8.66e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1489134430   9 KWRPQTFADVVGQEHVLTALANGLSLGRIHHaYLFSGTRGVGK--TSIARLLAKG 61
Cdd:PRK04132   12 KYRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGKclTGDTKVIANG 65
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
11-134 1.75e-04

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 41.72  E-value: 1.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  11 RPQTFADVVGQEHVLT--------ALANGLSLGRIhhayLFSGTRGVGKTSIARLLAKGLNCETGITATPCgvcdncreI 82
Cdd:pfam05496   2 RPRTLDEYIGQEKVKEnlkifieaAKQRGEALDHV----LLYGPPGLGKTTLANIIANEMGVNIRITSGPA--------I 69
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1489134430  83 EQGRfvDLieidAASRTKVEDtRDLLdnvqyapargrfkvyLIDEVHMLSRH 134
Cdd:pfam05496  70 ERPG--DL----AAILTNLEP-GDVL---------------FIDEIHRLNRA 99
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
11-133 5.94e-04

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 41.65  E-value: 5.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  11 RPQTFADVVGQEHVL--------TALANGLSLGRIhhayLFSGTRGVGKTSIARLLAKGLNCETGITATPcgvcdncrEI 82
Cdd:PRK00080   20 RPKSLDEFIGQEKVKenlkifieAAKKRGEALDHV----LLYGPPGLGKTTLANIIANEMGVNIRITSGP--------AL 87
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1489134430  83 EQGRfvDLieidAASRTKVEDtRDLLdnvqyapargrFkvylIDEVHMLSR 133
Cdd:PRK00080   88 EKPG--DL----AAILTNLEE-GDVL-----------F----IDEIHRLSP 116
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
48-215 6.83e-04

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 41.31  E-value: 6.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  48 GVGKTSIARLLAKGL--NCETGITATPCGvcdNCREIEQGRFVDLiEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLI 125
Cdd:COG3267    53 GTGKTTLLRRLLERLpdDVKVAYIPNPQL---SPAELLRAIADEL-GLEPKGASKADLLRQLQEFLLELAAAGRRVVLII 128
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 126 DEVHMLSRHSFnallktleeppEHVKFLLA-TTDPQKLPVTIL-------------------SRC-LQFHLKALDVEQ-- 182
Cdd:COG3267   129 DEAQNLPPETL-----------EELRLLSNlETDSRKLLQIVLvgqpelrerlarpelrqlrQRItARYHLRPLDREEta 197
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1489134430 183 --IRHQLEHILNEEHIAHEPRALQLLARAAEGSLR 215
Cdd:COG3267   198 ayIEHRLKVAGGEGDPLFTPEAIEAIYRASGGIPR 232
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
11-72 2.43e-03

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 39.68  E-value: 2.43e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  11 RPQTFADVVGQEHVL--------TALANGLSLGRIhhayLFSGTRGVGKTSIARLLAKGLNCETGITATP 72
Cdd:COG2255    23 RPKRLDEYIGQEKVKenlkifieAAKKRGEALDHV----LLYGPPGLGKTTLAHIIANEMGVNIRITSGP 88
AAA_18 pfam13238
AAA domain;
42-129 3.45e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 37.41  E-value: 3.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430  42 LFSGTRGVGKTSIARLLAKGLNCEtgitatpcgvcDNCREIEQGRFVDLIEIDAASRTKVEDTRD---LLDNVQYAPARG 118
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGFG-----------DNVRDLALENGLVLGDDPETRESKRLDEDKldrLLDLLEENAALE 70
                          90
                  ....*....|.
gi 1489134430 119 RFKVYLIDEVH 129
Cdd:pfam13238  71 EGGNLIIDGHL 81
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
44-65 4.11e-03

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 37.87  E-value: 4.11e-03
                          10        20
                  ....*....|....*....|..
gi 1489134430  44 SGTRGVGKTSIARLLAKGLNCE 65
Cdd:COG1936     6 TGTPGTGKTTVAKLLAERLGLE 27
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
122-230 5.34e-03

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 38.80  E-value: 5.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 122 VYLIDEVHMLSRHSFNALLKTLEEppEHVKFL-LAT---------TD---PQKLPVTILSRCLQFHLKALDVEQIRHQLE 188
Cdd:COG1224   295 VLFIDDAHMLDIEAFSFLTRAMES--ELAPIIiLATnrgitkirgTDiesPHGIPLDLLDRLLIIPTRPYTEDEIREIIK 372
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1489134430 189 HILNEEHIAHEPRALQLLAR-AAEGSLRDALSLTDQA--IASGDG 230
Cdd:COG1224   373 IRAEEEDIELSDDALEELTKiGVERSLRYAVQLLEPAyiIAKRRG 417
DNA_pol3_delta pfam06144
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
139-219 6.08e-03

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 428788 [Multi-domain]  Cd Length: 174  Bit Score: 37.65  E-value: 6.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1489134430 139 LLKTLEEPPEHVKFLLATTDP----QKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSL 214
Cdd:pfam06144  83 LEEYLSNPPPDSLLILFAPGKlderKKLTKLLKKKATVVECFTLKEEELIQWIQSRAQELGLQIEPEAIELLCELVENNL 162

                  ....*
gi 1489134430 215 RDALS 219
Cdd:pfam06144 163 SALAQ 167
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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