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Conserved domains on  [gi|94541118|ref|YP_588461|]
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putative metal-chelating domain-containing protein YeiW [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

YkgJ family cysteine cluster protein( domain architecture ID 10508572)

YkgJ family cysteine cluster protein similar to Escherichia coli UPF0153 protein YeiW, containing a conserved cysteine motif which might chelate iron or zinc ions

Gene Ontology:  GO:0051536

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CxxCxxCC pfam03692
Putative zinc- or iron-chelating domain; This family of proteins contains 8 conserved ...
 2-54 3.70e-05

Putative zinc- or iron-chelating domain; This family of proteins contains 8 conserved cysteines. It has in the past been annotated as being one of the complex of proteins of the flagellar Fli complex. However this was due to a mis-annotation of the original Salmonella LT2 Genbank entry of 'fliB'. With all its conserved cysteines it is possibly a domain that chelates iron or zinc ions.


:

Pssm-ID: 308985  Cd Length: 85  Bit Score: 38.37  E-value: 3.70e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 94541118    2 ECRpGCGACCTAPSISSPIPGMPDGKPA---------------NTPCIQLDEQ-QRCKIFtsPLRPKVC 54
Cdd:pfam03692  1 LCD-GCGACCKALGIKLTDEDTERLAPTgvaeededleeyvkvDGRCVFLDEEtCLCSIY--EERPLCC 66
 
Name Accession Description Interval E-value
CxxCxxCC pfam03692
Putative zinc- or iron-chelating domain; This family of proteins contains 8 conserved ...
 2-54 3.70e-05

Putative zinc- or iron-chelating domain; This family of proteins contains 8 conserved cysteines. It has in the past been annotated as being one of the complex of proteins of the flagellar Fli complex. However this was due to a mis-annotation of the original Salmonella LT2 Genbank entry of 'fliB'. With all its conserved cysteines it is possibly a domain that chelates iron or zinc ions.


Pssm-ID: 308985  Cd Length: 85  Bit Score: 38.37  E-value: 3.70e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 94541118    2 ECRpGCGACCTAPSISSPIPGMPDGKPA---------------NTPCIQLDEQ-QRCKIFtsPLRPKVC 54
Cdd:pfam03692  1 LCD-GCGACCKALGIKLTDEDTERLAPTgvaeededleeyvkvDGRCVFLDEEtCLCSIY--EERPLCC 66
 
Name Accession Description Interval E-value
CxxCxxCC pfam03692
Putative zinc- or iron-chelating domain; This family of proteins contains 8 conserved ...
 2-54 3.70e-05

Putative zinc- or iron-chelating domain; This family of proteins contains 8 conserved cysteines. It has in the past been annotated as being one of the complex of proteins of the flagellar Fli complex. However this was due to a mis-annotation of the original Salmonella LT2 Genbank entry of 'fliB'. With all its conserved cysteines it is possibly a domain that chelates iron or zinc ions.


Pssm-ID: 308985  Cd Length: 85  Bit Score: 38.37  E-value: 3.70e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 94541118    2 ECRpGCGACCTAPSISSPIPGMPDGKPA---------------NTPCIQLDEQ-QRCKIFtsPLRPKVC 54
Cdd:pfam03692  1 LCD-GCGACCKALGIKLTDEDTERLAPTgvaeededleeyvkvDGRCVFLDEEtCLCSIY--EERPLCC 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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