Table 1, Proteins present in P granules - WormBook

Proteins	Motifs/Functions	Associated with P granules in:	References
PGL-1	RGG box	Yes	Yes	Kawasaki et al., 1998
PGL-2	No recognizable motifs	No	Yes	Kawasaki et al., 2004
PGL-3	RGG box	Yes	Yes	Kawasaki et al., 2004
GLH-1	DEAD-box helicase motifs, 4 CCHC fingers	Yes	Yes	Gruidl et al., 1996
GLH-2	DEAD-box helicase motifs, 6 CCHC fingers	Yes	Yes	Gruidl et al., 1996
GLH-3	DEAD-box helicase motifs, 2 CCHC fingers	Yes	Yes	Kuznicki et al., 2000
GLH-4	DEAD-box helicase motifs, 5 CCHC fingers	Yes	Yes	Kuznicki et al., 2000
CGH-1	DEAD-box helicase motifs	Yes	Yes	Navarro et al., 2001
PIE-1	2 CCCH fingers	Yes	No	Mello et al., 1996; Reese et al., 2000
MEX-1	2 CCCH fingers	Yes	Yes^a	Guedes and Priess, 1997; Schisa et al., 2001
POS-1	2 CCCH fingers	Yes	Yes^[a]	Tabara et al., 1999; Schisa et al., 2001
OMA-1^b	2 CCCH fingers	Yes	Yes^[a]	Shimada et al., 2002; Lin, 2003
OMA-2^[b]	2 CCCH fingers	Yes	Yes^[a]	Shimada et al., 2002
MEX-3	2 KH domains	Yes	Yes^[a]	Draper et al., 1996; Schisa et al., 2001
GLD-1	KH domain; translational repressor	Yes	No	Jones et al., 1996
GLD-2	Cytoplasmic poly(A) polymerase (PAP)	Yes	No	Wang et al., 2002
GLD-3	KH-related domains; subunit of PAP	Yes	Moderate	Eckmann et al., 2002
Sm proteins	Splicing factors	Yes	Yes	Barbee et al., 2002
SPN-4	RNP motif	Yes	Unknown	Ogura et al., 2003
IFE-1	Translation initiation factor 4E	Unknown^c	Unknown^[c]	Amiri et al., 2001

Proteins

Motifs/Functions

Associated with P granules in:

References

Embryos

Adults

PGL-1

RGG box

Yes

Kawasaki et al., 1998

PGL-2

No recognizable motifs

Yes

Kawasaki et al., 2004

PGL-3

RGG box

Yes

Kawasaki et al., 2004

GLH-1

DEAD-box helicase motifs, 4 CCHC fingers

Yes

Gruidl et al., 1996

GLH-2

DEAD-box helicase motifs, 6 CCHC fingers

Yes

Gruidl et al., 1996

GLH-3

DEAD-box helicase motifs, 2 CCHC fingers

Yes

Kuznicki et al., 2000

GLH-4

DEAD-box helicase motifs, 5 CCHC fingers

Yes

Kuznicki et al., 2000

CGH-1

DEAD-box helicase motifs

Yes

Navarro et al., 2001

PIE-1

2 CCCH fingers

Yes

Mello et al., 1996; Reese et al., 2000

MEX-1

2 CCCH fingers

Yes

Yes^a

Guedes and Priess, 1997; Schisa et al., 2001

POS-1

2 CCCH fingers

Yes

Yes^[a]

Tabara et al., 1999; Schisa et al., 2001

OMA-1^b

2 CCCH fingers

Yes

Yes^[a]

Shimada et al., 2002; Lin, 2003

OMA-2^[b]

2 CCCH fingers

Yes

Yes^[a]

Shimada et al., 2002

MEX-3

2 KH domains

Yes

Yes^[a]

Draper et al., 1996; Schisa et al., 2001

GLD-1

KH domain; translational repressor

Yes

Jones et al., 1996

GLD-2

Cytoplasmic poly(A) polymerase (PAP)

Yes

Wang et al., 2002

GLD-3

KH-related domains; subunit of PAP

Yes

Moderate

Eckmann et al., 2002

Sm proteins

Splicing factors

Yes

Barbee et al., 2002

SPN-4

RNP motif

Yes

Unknown

Ogura et al., 2003

IFE-1

Translation initiation factor 4E

Unknown^c

Unknown^[c]

Amiri et al., 2001

From: Specification of the germ line

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Table 1Proteins present in P granules