TABLE 26.1

Summary of TRP Channels in Vascular Tissue

ChannelPresent in Arteries?Cell TypeFunction?
TRPC1yessmooth muscle [48]SOC [48]
endothelium [56]
TRPC2yessmooth muscle [23]?
endothelium [23]?
TRPC3yessmooth muscle [9]UTP-induced depolarization [31]
endothelium [61]SOC [59]
TRPC4yessmooth muscle [9]SOC [51,61]
endothelium [55,56,70]endothelial permeability [62]
TRPC5yessmooth muscle [71]?
endothelium [56,70]
TRPC6yessmooth muscle [28]PE-induced constriction [28]
endothelium [56,70]myogenic tone [33]
TRPC7yessmooth muscle [9]?
endothelium [70]
TRPV1yes??
TRPV2yessmooth muscle [42]stretch-induced cation current [42]
endothelium [53]
TRPV3yes??
TRPV4yessmooth muscle [36]EETs receptor [36,65]
endothelium [53,54]thermosensitivity [68]
TRPV5no——
TRPV6no——
TRPM1yes??
TRPM2yes??
TRPM3yes??
TRPM4yessmooth muscle [44,45]myogenic tone [45]
TRPM5yes??
TRPM6yes??
TRPM7yes??
TRPM8yes??

From: Chapter 26, Functional Significance of Transient Receptor Potential Channels in Vascular Function

Cover of TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades.
Liedtke WB, Heller S, editors.
Boca Raton (FL): CRC Press/Taylor & Francis; 2007.
Copyright © 2007, Taylor & Francis Group, LLC.

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