Table 2. [Select Features of ANKRD17-Related Neurodevelopmental Syndrome]. - GeneReviews®

Feature	Proportion of Persons w/Feature ¹	Comment
Developmental delay (DD) / intellectual disability (ID)	30/33	ID may range from borderline to severe.
Speech delay	28/31	Speech delay, incl absence of speech, has been observed w/varying degrees of ID/DD.
Ophthalmologic abnormalities	13/22	Typically strabismus & refractive errors
Growth deficiency	13/31	Postnatal height &/or weight ≥2 SD below mean
Feeding difficulties	11/26	↓ intake, which may require enteral feeding
Recurrent infections	11/32	Usually bacterial, but may also be viral
Gait/balance disturbances	8/24
Epilepsy	9/32

From: ANKRD17-Related Neurodevelopmental Syndrome

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Adam MP, Feldman J, Mirzaa GM, et al., editors.

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