Annexes

Annexes

Publication Details

Annex 1. Agenda of the Guideline Development Group meeting

Co-chair: Nancy Santesso

Co-chair: Kelly Dooley

Table

Publication Details

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World Health Organization, Geneva

NLM Citation

WHO treatment guidelines for isoniazid-resistant tuberculosis: Supplement to the WHO treatment guidelines for drug-resistant tuberculosis [Internet]. Geneva: World Health Organization; 2018. Annexes.

Time	Agenda item	Responsible
8:30–9:00	Registration
9:00–9:30	Welcome & introductions Meeting objective and agenda Declarations of interest	Karin Weyer
9:30–10:00	WHO requirements for evidence-based guidelines, GRADE methodology	Nancy Santesso
10:00–10:30	Global surveillance of resistance to isoniazid, pyrazinamide and fluoroquinolones	Matteo Zignol
10:30–11:00	Coffee break
11:00–11:45	Plenary—Presentation of IPD findings and GRADE tables from the Systematic reviews of Hr-TB regimen composition and duration	Dick Menzies, Federica Fregonese, McGill University, Canada
11:45–12:10	Plenary—Discussants present their perspectives on the implications of the findings for the approach to the composition and duration of Hr-TB regimens in adults and children	Discussants: Philipp du Cros (adults) and Farhana Amanullah (children).
12:10–12:25	Key issues relating to the PK/PD of anti-TB medicines of relevance to the Hr-TB treatment guidelines	Rada Savic & Michael Rich
12:25–12:45	Key issues relating to the detection of resistance to isoniazid, pyrazinamide and fluoroquinolones (molecular/phenotypic), and its relevance to the Hr-TB treatment guidelines	Daniela Cirillo
12:45–13:45	Lunch break
13:45–15:30	Plenary – Development of decision tables to formulate draft recommendation(s) based on certainty of the evidence, and other considerations (balance between desirable and undesirable effects, resources, feasibility, values and preferences, equity)	Co-chairs
15:30–16:00	Coffee break
16:00–17:45	Finalisation of draft recommendations and accompanying remarks	Facilitated discussion
17:45–18:00	Conclusion	Co-chairs