Conserved Protein Domain Family
PRK07373

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PRK07373: PRK07373 
DNA polymerase III subunit alpha; Reviewed
Statistics
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PSSM-Id: 236003
Aligned: 16 rows
Threshold Bit Score: 800.43
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
16329834    1 MVKVIGRRSLGVQRIFDIGLPQDHNFLLANGAIAANCFNKSHSTAYAYVTYQTAYLKANYPVEYMAALLTASSDSQEKVE 80 
166366494   1 MVKIIGRQSLGRKPVYDIGVEKDHNFLLGNGLIASNCFNKSHSTAYAYVTYQTAYLKANYPVEYMTALLTASSDNQDKVE 80 
170078979   1 MVKIIRRKFIGHAPTYDIGLSQDHNFLLGQGLIAANCFNKSHSTAYAYVTYQTAYLKANYPVEYMTALLSASSGNKDKVR 80 
56750961    1 MVKIVRRRSLGVQPVYDLGVATVHNFVLANGLVASNCFNKSHSTAYGYVTFQTAYLKANFPVEYMAALLTVNSGNADKVQ 80 
218248458   1 MVKIVSYRSLGKQFVYDIGVAQDHNFLLANGSIASNCFNKSHSTAYAYVTYQTAYLKANYPVEYMTALLTASSDNQDKVE 80 
172039636   1 MVKIIGRQSLGVQKVYDIGVEKEHNFLLHNGLIASNCFNKSHSTAYAYVTYQTAYLKANYPVEYMTALLTASSDNQDKVE 80 
218441796   1 MVKIISRQSLGIQPVYDIGVEKDHNFLISDGLIASNCFNKSHSTAYAYVTYQTAYLKANYPVEYMTALLTASSDSQEKIE 80 
284928952   1 MTKITSRKSLGIHEVFDIGLEKDHNFLLDNGFIASNCFNKSHSTAYAYITYQTAYLKANYPVEYMAALLTANSDNQDKIE 80 
22299612    1 -MKIVGRRLMGWQAVYDIGLAADHNFVLANGAIAANCFNKSHSTAYGYVTYQTAFLKANFPVEYMAALLTANSGDQDKVQ 79 
158333930   1 MVKIIQRRSLGLQSVYDIGLAQDHNFVMANGWVAANCFNKSHSTAYGYVTYQTAYLKANYPVEYMAALLTANSGDQDKVQ 80 
16329834   81 KYRENCQKMGITVEPPDINRSQRHFTPLGEAILFGLSAVRNLGEGAIEQIITARDNSEEkrFKSLADFCTQV-----DLR 155
166366494  81 KYRENCQKMNIDVEPPDINRSQKHFTPIGRKILFGLSAVRNLGENAIEAILKAREATGGk-FTSLGDFCERV-----DLR 154
170078979  81 KYRENAERMGILVLPPDINESDLDFKPVGQGIRFGLSAVQNLGENAINAILAAREAGP---FLSLSDLCSRL-----DLR 152
56750961   81 KYIANCAAMGIEVLPPDINRSGVDFTPTGDRILFGLSAIRNLGLGAIESILAARDVGGP--FLSLADLCDRV-----DTG 153
218248458  81 KYRENCQKMGIEVEPPDINRSQKHFTPVGEHILFGLSAVKNLGEGAIDNILKAREDEGN--FTSLADFCSRV-----DLR 153
172039636  81 KYRENCQKMGIDVLPPDINRSQKDFTPVGKQILFGFSAVRNLGEGAIDNILKAREEAEGq-FESLADFCCRV-----DLR 154
218441796  81 KYRENCQKLNIDVEPPDINRSQKDFTPIKEKILFGLSAVRNLGENAIENILKARQEAGGk-FESLADFCSRV-----DLR 154
284928952  81 KYRENCQKMGIQVLPPDISLSLKDFTPLENQILFGLSAVRNLGEGAIDSILKARIQLNTk-FNSLADFCSNT-----DSR 154
22299612   80 RYIATCLSMGIEVLPPDVNRSDIDFTPVGNKILFGLSAVRNVGQGVIEAILQARAEGGA--FQSLADFCERVpraggDSR 157
158333930  81 KYIATALSMGIEVEPPDINRSGVDFTPLDKNILFGLSAVRNLGQGAIEAILAARDEDGG--FESLAELCDRV-----DPR 153
16329834  156 VVNRRAIETLIMAGAFDGVQS--NRNQLLHDLELVIAWAQKRAKEKETGQLNIFDSLTAGESIKAkeaaNNGFEQEPSAP 233
166366494 155 VINKRALETLIYCGAFDKIQP--NRHQLIEDLELVVAWAQKRTKEKESGQMNIFDMLGGSTENKQ----ESEFEQSPSAT 228
170078979 153 VVNRRALETLITCGGLDSLHD--NRQAMLKGLDLMMDWAQLKAKEKASGQTNLFESLGDTAA---------AFDEAPVLP 221
56750961  154 SLNRRAMESLIHAGALDVLETgaNRQQLVADLPLVIDWANSRAKDRASGQGNLFDMLGSNDSNSS------PLDTAPKAP 227
218248458 154 VVNKRALETLIYCGAFDKVQN--NRKQLINDIELVTAWAQKRAKEKESGQLNLFDLVGNSTSQNGa--sNSDFEQAPSSP 229
172039636 155 SVNKRALETLIYAGAFDAIYP--NRKQLINDLELVVPWAQKRTKEKESGQLNIFDLMSGNTTESTe--aNTDFKQAPSAS 230
218441796 155 IVNRRALETLIYCGAFDQIND--NRHQLIEYLDIVIPWAQKRNKEKESGQLNIFDALLENIENKNd--nEVVFDQAPNLP 230
284928952 155 TVNKRALETLIYSGAFDSVSN--NRKQLINDLDLVISWAQKKAKDKESGQLNLFDLITNNADNSNl---DLEYEDVPSSP 229
22299612  158 ILNRRALESLIACGAMDSLHPqrNRNQLMQDLPLVLEWALARAKDRAVGQVNLFDMLAGDSSNES----KGSYDPAPSAP 233
158333930 154 VVNRRALEALIYSGALDAFDT--NRNQLVHDLELILEWAQSRAKDRAIGQGNLFDIMGGEGDAPT------SLETAPKAE 225
16329834  234 PVAEFSLQEKLQLEKEHLGFYVSEHPLKSVQRS-ARLLSPINLVDLDQYKVRQKVSAVAILVAVKKIITKKnGQPMAFLT 312
166366494 229 AVEDFSLQEKLKLEKEHLGFYVSEHPLKALQRA-AQVLSPINLADLEEHKTRKKVSAIVLLNAVKKIMTKK-GTPMAFLT 306
170078979 222 KVADLTLEEKLRQEKELLGFYVSEHPLEKLRSTiSPILSPISLTAIANHINK-KVSAVAILTDMRKIFTKAnNEPMAFIQ 300
56750961  228 AVPDYSPDEKLKLEKELLGFYLSDHPLKVVQEP-ARLLAPASISDLEDYCDRGLISTIALLTEVKPVVTKK-GDRMAILR 305
218248458 230 AVADFPLPERLKLEKEHLGFYVSEHPLKSIKKA-AAILSPINLSELEEQKSKQKISAVVMVNTIKKIVTKQ-GKNMAFLT 307
172039636 231 SVEDYSLQDKLKLEKEHLGFYVSEHPLTAVKKA-AKILSPINLNEMGEQKAKTKVSAVIMVNEVKQYTTKK-GDQMAFLV 308
218441796 231 SVADYSLDEKLKLEKEHLGFYVSEHPLNHILKK-AHVLSPVNLNELETQNSRKLISVVVMINSVKKITTRE-GKPMAFVG 308
284928952 230 SVEDFSLQDKLKFEKEYLGFYISEHPLRIIEEP-VSILSPVSFDEIIVQKAKRNITILSTIAEIKEYTTKK-GDQMAFLV 307
22299612  234 PVDDLPDTEKLRQEKDLLGFYVSNHPLKDIHRP-AAMIAPISLANLEQHTGQGVVSVIALLTGLKSITTKR-GERMAIVQ 311
158333930 226 PVEDFQESEKLKLEKEILGFYISNHPLREIERP-ARLMAPISLANLEEQPEKTTVSAIVLLTEVKPIITKK-GDRMAIVQ 303
16329834  313 LEDMSGQSEAVVFPSNYERLQDVLIEGSQQMIWGKVDRR--DDQYQLIVEDLEPVEEVKMVMLDLTPQEIANTSTQARLK 390
166366494 307 LEDASGQSEAVIFSDSYERLQKLLVEEATLMVWGKVDRR--DDRVQLIIEDAEPIETIKMVMVNLSLQDVVNQNRQNLLK 384
170078979 301 LEDISGQVEGIVFPRTYQKVEQLLQLDSRVIVWGKVQQK--EDRTQLIVDDLEPIEEVRMLMIRLSPSELHHTQSQQRLK 378
56750961  306 IEDLSGNTEAVVFPRSYERIGHYIEADARLMLWGKVDRR--DDQVQFIIEDAEPIDHVRLVLVELSVEQASDIVQQQRLK 383
218248458 308 LEDISGQLEAVVFSDAYEKIYDLLVEDARLIVWGKVDRR--DDKVQLIVEDAETIDKLRMIMVRLSPQQALDRVSQSSLR 385
172039636 309 LEDGSAQVDAVCFPESYKRIREVLIEDSRLIVWGKVDYR--DDKVQLIVEDAEPVETVRMVMVNLSLEQAINQVSYHSLK 386
218441796 309 LEDTTAQVEGILFPSAYPRVQEVLSVESPLIMWGKVQKNkdEDKIQLIIEDAEPVEKVKLVMINLSIQEAMNVDRQTTLK 388
284928952 308 LEDTSRHIEGVCFPKSYKKIKNVLTKDSVLIIWGKVDFR--DDKVQVIIEHAQDIDSMRIVIIDLSLEQATNKISCHNLK 385
22299612  312 LEDLTGQAEAVVFPKAYERIHGQLQLDHRLLLWGTLEMR--DDRPQLLIEDAEPLEEVKLVLVDLPVEQAGDIQAQSRLS 389
158333930 304 MEDLSGKAEGVVFPRSFERIGEYIETDLRLMIWGKVDRR--DDRIQIIVEDAEPIEEVKLVMVEIPAQDAGNIQQQQRLK 381
16329834  391 QILqsHAPQ-KEQMKIPVVACINEGPTKHFIRFGENYWVNDYGTAVASLQELGFRARLEPLLPQ 453
166366494 385 SIL--QSGD-KQKAKVPVIATIGAGTQRQFVRLGQNYWVEDDNSVVESLKVAGFLANSAPLINH 445
170078979 379 QILsqQAGDkKKRGRIPVIVIVGRGGDRTFIRLGQDYWVEDDHQALLALRQGGFHVYRENLIPQ 442
56750961  384 ELLlqQKRE-EERSKVPVVAVIQAGSDRYFVRLGAQFRVEDPEEAVEALQAADFQARAEALLSP 446
218248458 386 GILqeHSGD-KNQAKIPVIAIITTGQQQQFIRLGSNYWVQNELNAITSLNNAGFNAYTSPLMNN 448
172039636 387 GILqeHSGD-KNKAKVPVIAIIGSGENRQLIRLGQDYWVQNDQSVIEALRKAHFNAYPTPLVSD 449
218441796 389 ALLqnRNGE-KNTGKIPVLATIGKGKNRQIVRFGSHYWVQNEYSTIQDLTKAGFSAEAQPLS-- 449
284928952 386 SILsgHAGK-NNQTKIPLFIFLQDKGNKKLIRLDESYWPNDEKLVINALNKVEFNSYSISLLEY 448
22299612  390 EVLkqQAGE---MPKVPVVVKVTDGYHAQYVRLGPQFRVEDADRARHALTSAGFQAHASELLSL 450
158333930 382 EILrqQAGE-ENAAKVSVIAKIKGDEKSQLVRLGSQFRVQNEHMAVQALASAGFRASSSVLVDL 444
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