3DYD


Conserved Protein Domain Family
tyr_amTase_E

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TIGR01264: tyr_amTase_E 
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tyrosine aminotransferase, eukaryotic
This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Statistics
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PSSM-Id: 273529
Aligned: 5 rows
Threshold Bit Score: 693.065
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3DYD_A             24 WSVRP-SDMAKKTFNPIRAIVDNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSR 102 human
AAD45375           41 WSVKP-SDMSNKTFNPIRAIVDSMKVKPNPDKTMIALSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGYLSSR 119 Neovison v...
CAB03090           43 WNVLPqSAHSKNTVNPVRKIADACAVPPHPEKKVIKLHLGDPSVGGKLPPSEIAVQAMHESVSSHMFDGYGPAVGALAAR 122 Caenorhabd...
AAG00298            9 WDVSM-SNHAGLVVNPIRSISDNAKPSPSP-KPIIKLSVGDPTLDKNLLTPASHMEKLKKVVDSQDWNGYLPTVGAPEAC 86  Trypanosom...
FlyBase:CG1461-PA  79 WEIKG-SKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGDPTTFGNLKAADETMKAVLHSLESGKYNGYASTQGHEIAR 157 fruit fly
3DYD_A            103 EEIASYYHc-------PEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNL-LPE 174 human
AAD45375          120 EEIASYYHr-------PEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILVPRPGFSLYRTLAESMGIEVKLYNL-LPE 191 Neovison v...
CAB03090          123 EAIVERYSs-------ADNVFTADDVVLASGCSHALQMAIEAVANAGENILVPHPGFPLYSTLCRPHNIVDKPYKIdMTG 195 Caenorhabd...
AAG00298           87 DAIATWWRnsfvhnkqLKGSIVKDNVVCCSGGSHGILMAITAICDAGDYVLVPKPGFPHYETVCKAYGLGMHLYNC-RAD 165 Trypanosom...
FlyBase:CG1461-PA 158 KAVAKYSAhq-----rPDGEIDANEVVLCSGCSSALEYCILALADRGQNVLVPRPGFCLYYTLAQGLDIEVRYYDL-LPD 231 fruit fly
3DYD_A            175 KSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSD----CKYEPLATLS 250 human
AAD45375          192 KSWEIDLKQLESLIDEKTACLIVNNPSNPCGSVFSRSHLQKILAVAARQCVPILADEIYGDMVFSD----STFEPLATLS 267 Neovison v...
CAB03090          196 EDVRIDLSYMATIIDDNTKAIIVNNPGNPTGGVFTKEHLEEILAFAHQYKLIIIADEIYGDLVYNG----ATFYPLASLS 271 Caenorhabd...
AAG00298          166 NNWEADLDEIRQLKDDKTKLIVITNPSNPCGSNFRRQHVEDLVRLAEELRLPMFADEIYAGMVFKGkdpnATFTSVADFD 245 Trypanosom...
FlyBase:CG1461-PA 232 QQWRADLVQLESLIDENTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVFPG----SKHLAVSSLT 307 fruit fly
3DYD_A            251 TDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNeIRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLK 330 human
AAD45375          268 SNVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNeIRDGLVKLSQRILGPCTIVQGALKSILHRTPQEFYHNTLSLLK 347 Neovison v...
CAB03090          272 PKVPIITCDGIAKRWMVPGWRLGWLIIHNHFGVLTD-VKNGIVALSQKIVGPCSLVQGALPKILRETPEDYFVYTRNVIE 350 Caenorhabd...
AAG00298          246 STVPRVILGGTAKNLVVPGWRLGWLIYVDPHGTGRG-FLDGLKRVAMLVCGPNTLAQGAVSEALLNTPQEYLDGIVSKIE 324 Trypanosom...
FlyBase:CG1461-PA 308 TEVPVLSCGGLTKRFLVPGWRMGWIIVHDRKNRLRD-AIVGLKNMCGRILGSNTIIQGALPDILTKTPQSYFDGVIDVLH 386 fruit fly
3DYD_A            331 SNADLCYGALAAIPGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFIRVVITVPEVMM 410 human
AAD45375          348 SNADLCYGALAAIPGLQPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFFRVVITVPKVMM 427 Neovison v...
CAB03090          351 TNANIVDSILADVPGMRVVKPKGAMYMMVNISRTAYG---SDVSFCQNLIREESVFCLPGQAFSAPGYFRVVLTCGSEDM 427 Caenorhabd...
AAG00298          325 ESAMYLYEHLAECVGVVPTMPQGSMYVFSKIELEKFKDIKTDVEFFEKLLEEENVQVLPGSIFNLPGFMRVTTTRPVSVY 404 Trypanosom...
FlyBase:CG1461-PA 387 SNAMLAYKMLKQVRGLDPVMPNGAMYMMIGVSIERFPEFKDDTHFVQEMVNEQSVFCLPGSCFEYPGYVRIVLTVPGAMI 466 fruit fly
3DYD_A            411 LEACSRIQEFCEQHY 425 human
AAD45375          428 LEACSRIQEFCELHY 442 Neovison vison
CAB03090          428 EEAALRIREFCYRNF 442 Caenorhabditis elegans
AAG00298          405 REAVERIKAFCKRHA 419 Trypanosoma rangeli
FlyBase:CG1461-PA 467 EEACSRIAEFCDRHY 481 fruit fly
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