Conserved Protein Domain Family
DUF4788

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pfam16032: DUF4788 
Domain of unknown function (DUF4788)
This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is approximately 230 amino acids in length. There is a single completely conserved residue D that may be functionally important.
Statistics
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PSSM-Id: 406440
Aligned: 23 rows
Threshold Bit Score: 206.797
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KMZ03652             17 VVTSLDLEK-PVKET-ELLEAQVKFGGVNIKITNSRINVQDFINNRLTQFTTSPSALRQSLEDQGMQISARYAGSSLGTN 94  
WGS:AAQB:GK13152-PA  13 VIPKTNLPPpKEEDTsSEYVFSVRIFKDFVDLPFDRMWAEDFADAPLGQILSTPCELIGSLTSKGVCVTLRNKQGLLGSG 92  
WGS:AAPU:GI23384-PA  14 ILEKSTLKHkPGEPC--PYTYMVCPYKQYLKVTDDRIYGKEFPAEALGEFVANPYELAESLTSKGIRLAIYENGQLLGCG 91  
WGS:AAPU:GI23385-PA  13 IVLQSSLPVvEGEES--PYNYRVRLYNEFLELSPDRVVTEYFPNNPISTFVASPCDLVGSLSSKGICVTVYENGNLFGCG 90  
Q8ING2               12 VITNLNIFGvTIDEP-AKLLVETKVAGKSVKVTSSRINVDQFVAGREFELPMEASTLRQSLEEKGLTLAGVYQGSTLGKA 90   fruit fly
XP_001955463         15 VVTHLELKGiNAE-P-QNLNASIKFPQRAWKMGASRINVTDFPPNREEQIVSSPCRMRDALEANGIVLGVLYSGSTVGAA 92  
XP_002070677          9 igkhslsgHdNND-----------------------------------QFASDPETLRQGLEKAGMPLLVRYGGNLIGNG 53  
WGS:AAPU:GI24544-PA  11 IVTRLELSKhEIDEP-QNLLVNVDFNKNQLKVTSSRINVDQFDVMKGINCQTDPAVLRDYLEANGLTVIVRYNGVVLGKG 89  
XP_001999493         16 IVTRLQLTKdKVDDP-SKLIVNLKFNNIPMSITPSRINVDNFKAGRQSAITCDPEILRQGLETQGMPMTVRYSGMTVGTA 94  
XP_001994278         17 IVTRLQFIKdKIDDP-ADLLINLKFNSIGVSITSSRINVGDFRAGRCTEFVSDPSALRTNLERNGMPITVRNKGMTLGTA 95  
KMZ03652             95 VLLFPDTFIDKISSKMNDLFFEATINLMRRADCIGTITIrlVLIIKCidTDIIKEPRrssS-PRmsrksiaedi------ 167 
WGS:AAQB:GK13152-PA  93 TTALTPLVLRQLTDPTFEVIQTIDMDIVHHGKNVDTIQM--KLKFSAehPDVDPENN---CpYD---------------- 151 
WGS:AAPU:GI23384-PA  92 SFRPIDDILRPLTEPTFTATGAYVVDAEQEGVRVARVDF--NIKFSAadPQLDSRMIpfgC-FD---------------- 152 
WGS:AAPU:GI23385-PA  91 TCRPSTGLLRMLADPTFSCTESLNITLEKGKRRMGHLHL--KINISSvdPDLDARLLpfgC-YD---------------- 151 
Q8ING2               91 TGNFPVEFLDKISPTMNDLVHEDTLDLVRRVDVVGTVSVliRLTVKCe-EHPEQKPSrqsL-SRtskssmilp------- 161  fruit fly
XP_001955463         93 TMSFPQEFLDKICPTMSDLLHTDNLQLMRRKDVVGSVTIvvRLTLKCe-KDRDSITTkiaD-SRakvqfiqpgvtelevp 170 
XP_002070677         54 KLIFPEIVLNKIDIGMNDLMHADTCELKRNDQKVGIVELlcRITIKC--DEMVSGSDe--R-PK---------------- 112 
WGS:AAPU:GI24544-PA  90 CVPFLESFINQIDYDMDYLTYASTCNLFGNHSLVGSIDVmcLLTIKC--ESQDDFVGp--C-K----------------- 147 
XP_001999493         95 TLKFPQSFIDRIQDGMSDLFHQDSCTLVKRDAVAGTLEVfcSLIIKC--ETLIETTEp--C-KK---------------- 153 
XP_001994278         96 LVALPQSFIDRIEVGMSDLVFEHKCSIIRRDAEVGTLEFlcTLIIKC--DEQPQQTVt--C-NS---------------- 154 
KMZ03652            168 -lpkkemkkeSCQGLGPTINPQDVMFVIGDPDPLlkiPSEPCSEllf-edgDVRLDLDLQRYRSLENRrlvlpddDPCLK 245 
WGS:AAQB:GK13152-PA 152 ----------VCRTVDKSLHPKDVVFTLGRSCKC---PTTSCIT-------DQRLMSGINAPFKCVHS-------PNTPQ 204 
WGS:AAPU:GI23384-PA 153 ----------ICRTLDTSINPRDIIFTLGRSKRT---ASVACIT-------DKRLMSFGEAPFSCVRK--------EVNS 204 
WGS:AAPU:GI23385-PA 152 ----------VCRPQDKSVNPRDIIFTLGRSRKC---AGTTCIT-------DERLMSQAGAPFNCTHN-------ENPPA 204 
Q8ING2              162 --kkeksgrvSCASQGPTFNPQDVMFLIGDPDPLlriPSEPCSElls-eigDERLKLDLQRYKSLENRraifpddDRCPK 238  fruit fly
XP_001955463        171 qdvpktkrrvSFSSLGHTINPQDVMFTIGDPDPVleiPSNPCSElae-adgDRLLSLDLARYSSMKNSrvvlpddLPCLK 249 
XP_002070677        113 ----------TCADLNSVINKQDIMFLMSTADPCa-kHQELCNNvseseegDARLRLDIDRYRSMNSRvdp-stiEEPEP 180 
WGS:AAPU:GI24544-PA 148 -------------DACGNIAKKDIMILMRNPDTDa-iADKSYLTeaeeqenDIQLGLDLSRYRSINQRms---qsSEDSS 210 
XP_001999493        154 ----------SCANLGKAIKEADILFVIGRNDPCd-sVCEPCAEqidtvegDERLRMDLSRYRGDNQRas---lpPAENY 219 
XP_001994278        155 ----------ACENLAKAFNPTDIMFVVGAPQPCp-lPCEPCLDelepeegDERLQLDLDRYRRRSQRvt---tpPEKIC 220 
KMZ03652            246 EKPSIsqLRQLTHHYSRIIGMV 267 
WGS:AAQB:GK13152-PA 205 GWSCC--LTGGEAPPPPPPEQD 224 
WGS:AAPU:GI23384-PA 205 TAGCGcvLHGTDTVVPKALDRS 226 
WGS:AAPU:GI23385-PA 205 GKECScgVRGAKT--PPAMDPT 224 
Q8ING2              239 QKPSFmqLKKLTEEYSNIIDSV 260  fruit fly
XP_001955463        250 EKPSLrqLKEITRQFTHIVDSV 271 
XP_002070677        181 EVISCnvLRKVTDHYVDVIDSV 202 
WGS:AAPU:GI24544-PA 211 GTEACylLRAMATEYAQIIDSV 232 
XP_001999493        220 KLEATsvLKAMTDQCGLAIDSV 241 
XP_001994278        221 GMEACcqLKTMTKQYEECIESV 242 
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