Conserved Protein Domain Family
AIP3

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pfam03915: AIP3 
Actin interacting protein 3
Statistics
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PSSM-Id: 427585
Aligned: 89 rows
Threshold Bit Score: 349.138
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KDE09798      740 FLQIGREVKKARLVEE-PTIASLKLVFVERFQYNPGANDFPA-----IYVRDGEFGISYELEDMKDVRNGSVLSLN---- 809 
EPB85501      397 FLQIGKEVQKVKYNGE-ISIPALNMLFLEKFSYSVGQNDFPK-----IYIQDPAVGVSYELVDLSEVRDKSMLSFNindk 470 
EIE75760      302 FLQIGKQVKKTIYQGE-LSMSALNMLFVENFNYSSRQNDFPN-----IYIRDPTIGVSYELTDMNEIKNKSVLSLHideq 375 
EKD04427      500 YLQLGRQVKKTAIDLP-TDMSTLKLLFMERFEYDPGMEDFPN-----VYIRDNKTGVQYELEDLKDLQEGSVLTLD---- 569 
Q5K9A7        642 FLQIGRKTKRHVLELP-ITLEALKLVFMERFEYDPGKEDFPD-----VYIRD-RDGMEYELEGVEDLREGCTLCLN---- 710  Cryptococcus ...
XP_018230676  352 FLQFGSQIKKVIHDKD-ITLDNLRILFTEKFQFTLDNNSFPP-----FYIQDIHTKILYELEDMQDIKDHSLISLK---- 421 
EMR09133      357 FLQYGSQVKKVTHSKD-ISLNGIRALFIEKFEFNPCNDNFPP-----LYIQDDRTRIFYELEDAQDITDRSLISLK---- 426 
XP_002175713  403 FIRWSNITKKIPMPSElHTPGEVYNVFKASFH------DIPDdealiFEIRDEETQINYLLEDLSEVKNGSLLVAVqk-- 474 
O13735        793 FLRYNNQTRKVKVESPlSNANELGELFSNVYKISFSGDSY-E-----LNIEDPDTKISYLLEDLSDLKYKSLVSFMfkeq 866  Schizosacchar...
XP_013022886  601 FLKLNNRTRKAISPFAvDTQEKLQALFQSKFENEFEDVPF-E-----FYIEDYDTKVNYLLEDYSDMKFKSLIIAQkqlk 674 
KDE09798      810 -----------------------------ID----TVEQVKQ---------------HIDQGLLTL--------SQDIKE 833 
EPB85501      471 edqkesqkewlsevttafnkelsetrrmfTE----QMDEIKK---------------QIVESNARNqeadeekeRSLIQQ 531 
EIE75760      376 eeqresqkelmsalsdlfrkelketsqilMN----QIEEMKK---------------QFGLFNETI-----------IRE 425 
EKD04427      570 -----------------------------IE----PLDQVKQ---------------HFDLTFASL--------SAEIKE 593 
Q5K9A7        711 -----------------------------IE----PLDQVKL---------------HIDSTFATL--------VQEMKE 734  Cryptococcus ...
XP_018230676  422 -----------------------------IQ----AEDTSKK---------------ILEEELSSL--------TKEFQS 445 
EMR09133      427 -----------------------------IQ------DVPNK---------------ALEDGISSL--------TKELQS 448 
XP_002175713  475 ---------------------------pdVEqedePVKEVEPe--------------PVKQENPEVte----mlMKKLEE 509 
O13735        867 d-----------------------ankkrEDfhsgEVSAIQHssaqn------tlddHVNTTTHESpssafteiLERLKA 917  Schizosacchar...
XP_013022886  675 v------------------------------peesPVDNVEAvgeatrpyeifskddGINNSsif------eeiLQRLNV 718 
KDE09798      834 LRSTMtamrrvssha-----------------------gmfspelatPAAAQTLPEPSEQQYQDAAQKVLrmRRlgsipn 890 
EPB85501      532 VTTHI------------------------------------------LNQHQQLKPQPADDESKQKEEEKemAPepeast 569 
EIE75760      426 ITTEIlnd------------------------------------lnnSRQPKDDQPQRNKQEQPQEASTQkvDP------ 463 
EKD04427      594 LKSALtqpkrlstaqpltnsllsv----spsqprlplgtpdqtmvinSSPRSPEVEISTPTAPDA--------------- 654 
Q5K9A7        735 LRQALdkerettkrlsvlaspsvagdpasltpstsplqppasaislpAPTPLVVGPSEDH-------------------- 794  Cryptococcus ...
XP_018230676  446 LKTSI------------------------------------------EGQKEMISEMTSRPSTCLSKSTIesFSkqe--- 480 
EMR09133      449 LKTSF------------------------------------------EGQREMISEMASRPSTCVSKVTLesISrhe--- 483 
XP_002175713  510 IEDKI------------------------------------------SQLKLAPAPAAEKESQPTVRVSSdgTS------ 541 
O13735        918 IEQNI------------------------------------------STNHTNDSAALKSSEDHSKLANNfsVP------ 949  Schizosacchar...
XP_013022886  719 IERKL------------------------------------------GSEHITNATIQSSSASKTAKSDKvvTN------ 750 
KDE09798      891 maasanadkaspsdpntpkpsqastssvgapplpaapkgsptlstsskmgggggkgaldanqvVETLRTQHKQVQDLRRE 970 
EPB85501      570 spmp-------------------------------------------------vvenagpiisKEQFEAQRKEIETLRRD 600 
EIE75760      464 ----------------------------------------------------------------EQWKKQFLEIENLKRD 479 
EKD04427      655 -----------------------------------------------------------------NLRAHYDEVQSLRRD 669 
Q5K9A7        795 ---------------------------------------------------------------LKQIQEQHEELESLRRE 811  Cryptococcus ...
XP_018230676  481 ------------------------------------------------------------ttiLKIQKSCPYIIKNIREE 500 
EMR09133      484 ------------------------------------------------------------nifLRTQKNHSDIVKNIRQE 503 
XP_002175713  542 ----------------------------------------------------------------SQLAWYHQEVKAAKLE 557 
O13735        950 ---------------------------------------------------------------DSIDHKFYQQVKNMQLE 966  Schizosacchar...
XP_013022886  751 -------------------------------------------------------------------ATNYQQVKNMQLD 763 
KDE09798      971 LGVLRQVYSDFGHHTKHIFAAMKVETS-RVH-------KLASTSKv-GKSRTFVEAGVQKLDADVSELVVKVDEISDSIE 1041
EPB85501      601 VAVLRQLERELREGAASVISEIKEKAE-KVKeeaikkaDAELNQT--STARSHLEEGKKNLLEKSDKVTSRLEDLQDTID 677 
EIE75760      480 IVVLRQLDHESKEEANQMIEEIKMKATtIVNs-----sIKKDSQI--SSARFILEEGKKSLLEKSDKITNRLEDLQDTID 552 
EKD04427      670 LAIMRQLHLDFINQTKESFSTLREQNT-AMR-------EVVKTKM--GGSRALLDNSKSKLEAQCQDTIQSVEEVSDIID 739 
Q5K9A7        812 LAITRQSHAEHINESSAIISSLKDEIA-QIK-------KVTSTNP--NSNRGLVDRSKAELDTQCTETIKAVEDITDIVD 881  Cryptococcus ...
XP_018230676  501 LETLRNIYTKFASSIKTSMLDIEAKAK-KVK-------EVTIKKL--GGSRDFIELGKKKLETETQSLVTRIENLSDLVG 570 
EMR09133      504 LDSLRTIYTDFTLSMKSSMMNIDSKAK-KVK-------NVVFGKL--GGSRHFIELGKKKLEVETQSLVTKIENLSDIVS 573 
XP_002175713  558 LVAVKQSLISMLARVPLKFEEFKNKVL-DIY---------GSTNNntVLERTFINKSKLKLESNLANIVSNFDDLNDLVE 627 
O13735        967 LASLKQISAAFFTRIPLKIKDFKKEIN-AFN---------EKGSLdfQFGRGFVLSSKDRIEREVKNVVEKFDEVNDQIE 1036 Schizosacchar...
XP_013022886  764 LASLKQVFAASFTKIPLQLNEFRKQMG-IIN----------EKASgfGFDRGYILKSKDTIEAVAKSLVERFDDINDQIE 832 
KDE09798     1042 LMRADVV-RGVRPRPGYLSETALTLKKIVEQRDAVAEKLGTTKPTWAHTWSEELAKVLGEQETVQKHESMLVDLCDDLND 1120
EPB85501      678 QLKLDVTqRKCRPSEAQMTHCANERKALAEEIEEFGKYIAQVKPRWKKTWEMELQTIVKEQQTLKDQEYLLSDMKDDLDA 757 
EIE75760      553 QLKLDVTqRKCRPSEIQMKHCAKERKELSKEIEEFDMFIAQVKPKWKKTWEYELQTIVKEQQALKDQEYLLTDIKDDLEA 632 
EKD04427      740 GAREDALrRGITPSKSKMGKIREDLTKATALVETFTTDVAAAEPTWRATWLTELQRVTEEQRLLAYQNKLAADLKNDIKD 819 
Q5K9A7        882 AARIDAYkRFVTPSKQQMATIQSDLQKARQLVEDFTSAVKIADPTWRGTWQTELHRVMEEQKLLHHQTKLCGDLKKDLED 961  Cryptococcus ...
XP_018230676  571 NLRVDVInKKTRPSSQQFDDIRKEEAQIQKDMISLISHLENLSPCWRQLWETELQNVVEEQEFLTHQEGFIEDLKSDISA 650 
EMR09133      574 SLRIDVInRKVRPLPQQLDDVRKKEAQIQKDMISLINHLQSLSPCWRQLWEMELQNVVEEQEFLAHQENFIEDLKADIVS 653 
XP_002175713  628 CLRADVLhRKVRPGLDQVAALRKDKKLLAKEIEDLEATLNSVTPSWKKQWETELNQIVQEQEFLNNQSEMILDLKRDLDS 707 
O13735       1037 LMRSDVLlRKVRPGLDQTSQLNEESAYLEKRIQTLERSLEEVTPIWKKQWERELNAIVQEQEFLDSHTVLISDLKRDLSA 1116 Schizosacchar...
XP_013022886  833 LLRSDVLlRKVRPGLDQISYLVKEKESIESSIHELQKAIEEVTPTWKKQWEKELNAIVQEQEFLDNHTNLITDLNKDLDS 912 
KDE09798     1121 VKDVLKNIEAVAKSTKKLHR-TKSRhrlaGSGDDGTegndldpgQSLSNVLLEVKHLQPDANRRLEAIARAEKQREIDNA 1199
EPB85501      758 LLEVFEQLEKIYAYQANARP--QPRefrvAPAEEGF--------EGMSSVFKQVSTIDVDHTRRLRALEQAEKMRQRELA 827 
EIE75760      633 LSEVFEQLEKIYAYQVSAKP--IVRefrvTPVEEGF--------EGMASVLKQVATIDVDHERRLRAMEQADKMRQRELA 702 
EKD04427      820 ATEMLDNVQAFVDQRKAGGR-ANQNrfmpSSPDEGG--------GGITNLLMEIRTKEADPSQRLRAIEEQQRARERELA 890 
Q5K9A7        962 AESMLGNVQTFVEQRVAGTR--TARirvgADAEVEG--------GGISSLLMEIRTKDSDPEQRLRAIEAQQRARARERA 1031 Cryptococcus ...
XP_018230676  651 TMDIFANIVTYYEYKEKRIHrss----hsITTQDSI--------SSSNTHHSEARNTKLE-NIRNNSIEKEGKHKETNFV 717 
EMR09133      654 TMEIFGNIVTYSEYQEKNAHln-----ysLLKQGST--------DSLNTLNLEARNAKPELEIRANTIPKIEK-QENNFR 719 
XP_002175713  708 VSTVLANVTAIAEYQNQTPLeSKPLqlltASNLDVG--------EYRNRINLEITKLKPDSESRLEAIRRAEALRKKNLS 779 
O13735       1117 LSTVLSNVSAIAELQAKSSIkSKPLtlktATESEIK--------GYRDQIQLEVLNLKPDSEARLQAIERSELLQKKRLL 1188 Schizosacchar...
XP_013022886  913 ITTVLSNVSAIAELQAKSSIkSKPLavkpSAG-DMK--------EIREKIHMDVLKLRPDSDVRLQAIERFEAFQRKKVL 983 
KDE09798     1200 NRTDEFADELEEFVQRGKLKKSGGVEEAERLRQARS 1235
EPB85501      828 NRIDDFEKELVGFVETKKLKKTGGAMEIDRLRKQKD 863 
EIE75760      703 NRTDDFERELVSFVNTKKLKKTGGALEIDRLRKQKD 738 
EKD04427      891 TRTDEFQNELSGFVAGKKLKKTGGTDEAERVRQRRQ 926 
Q5K9A7       1032 NKVDEFEAELKGFVGGKRLKKTGGAEEVDRLRGRKD 1067 Cryptococcus neoformans
XP_018230676  718 FHIDKFKNELNEFITNVKFKKTGCMNDIERFREEKD 753 
EMR09133      720 FYIDKFKYELDEFLSKTKFKNVGCMDEVERIRKEKD 755 
XP_002175713  780 LMEDKFKAELEEFVKEDKFHKIGGIEEVNRLRELKD 815 
O13735       1189 QRVDEFSKEVKTFVENEKLNKIGGAEEADRIRTIQD 1224 Schizosaccharomyces pombe 972h-
XP_013022886  984 FHEDEFAKELKEFIKDDNLRNIGGVEEVERRRSVQD 1019
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