Conserved Protein Domain Family
DUF2417

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pfam10329: DUF2417 
Region of unknown function (DUF2417)
This is a region of a family of proteins conserved in fungi some of whose members also have the Abhydrolase_1, pfam00561, domain in their sequence. The function of this region is not known.
Statistics
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PSSM-Id: 431216
Aligned: 65 rows
Threshold Bit Score: 164.313
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003686100  23 ETEPLLNKhkqkpns-----------------lkksprrIGEESSEPIymi----eneSQQNNSQleeyVLQPNLKKIyl 81 
CCK71993      47 ENTPLINKpktshp-------------------vkshrnIGDRTASYGgvv----gpgDDRNTGDseahGGDEPRFQThk 103
XP_003955891  43 ENAPLLGKqdrnvt-------------------kkshrtFGSNGNGATd--------nASHEDRDsefyANENGRFQYhq 95 
CCC71141      26 ETAPLLPNdtaipgsantvdnnnndaaittanpkqshrnFGSHSKSSPn--------eDEQQDQEdreaSIPTERYKLhr 97 
XP_001644098  33 EAQPLLGSskvaar-------------------shptrvIGG---NNShqsnndsisrSSQQPIGrsneNLQFNLLKIlr 90 
CAR26707      47 EQEPLLGRstsgk---------------------pshraIGVQPQPIPnp-------sEEDERTFdfesQFQRKLFGIhr 98 
XP_003679861  48 EHEPLLPEnnttqg-------------------kpsrraIGVPPNAISst-------eRAENEEAdtesYFQRNQYRVhr 101
P53925        26 EAQPLLNNnh---------------------------rtLGAGSANGPav---------nEGRDIesdgFIKDSLFQIrk 69  Saccharomyces c...
XP_002553902  42 ENEPLLREtqakp----------------------shrsIGQVPTDGHlpn---------------eieGSQGRQFKTrq 84 
Q6CIU6        55 EHEPLLEGqrsgk---------------------sshrtLGAVAPQPInvsnssspgdDFSDDDSelprDPSDLLYSVrr 113 Kluyveromyces l...
XP_003686100  82 rykkfrRYSSLILNVCIFVNILWLIFTLVTSYFfsfeLQPIIHKRYSGYNDLCIITISIISNCLNLWSnnIEIYSHLDFD 161
CCK71993     104 dysifqHNWRWTMNVILFINTLFLVFVFICYFFlnfgFGTG---RNESFDKLLFISVALIGNCFNLWFndIWLISSWDYF 180
XP_003955891  96 nyrsflTNWKCILNVVLFLNTLVLVLLFVSDYFie----ilPADRNTTFTNFVLVIISLIGNAFNLSFtdIGLYSSFDWD 171
CCC71141      98 syrlfiHNSRWILNILILLTSIWLVMILISDFFfn----irFNNRLTGFKGMILLFISLITNCCNFWFndLGLYSPSDYK 173
XP_001644098  91 syksfiRVIRWISGISLVISIVWFIITLISDFFfgldSLIGFKDGDNSFNEIVLILVSTVANYSTLVFnrLGFYSSLDLK 170
CAR26707      99 qyrlfiSNSRWILNIFIILNTVWLVTTLIGDFFfn-inIFKTNNRYCSFSDLTLIFISIIANIFNLWFnkLGLYSSLDYA 177
XP_003679861 102 kyrlfiHNAKWVVNIFIVINTIWLVTTLISDYFfd-isLFHSNNRSNSFNDITLIFISIVTNALNLWFnkLGLYSPLDYV 180
P53925        70 gyrifiHNSKWILNILILINTIWLVTTLISDFFfninILFGFSNRYASFNDLTLIFISIIANSFNLWFnkLGLYSALDYS 149 Saccharomyces c...
XP_002553902  85 kyrvfvQDSKIILNVLIFINLVWLITTFIMDYFfn-igFLHFSKRLTSFNDLCLIFVSIVANSVNLWSnrVGLYSTLDQG 163
Q6CIU6       114 gyrnfiHKSKTLLNIMIFINTLWLVTTFISDFFfn---inFLRNRITGFQDLTLIFVSIVANSLTLWFnkIGYYSSLDQY 190 Kluyveromyces l...
XP_003686100 162 LNIILFALTIFNLMLLKIVRYTSERIGIIGVITYAWAATTFGIGILLDWKTANFKKQIVVV---YNSGTSQndnarnins 238
CCK71993     181 MDMVLTGLPLTNLALFMLTSYTRTRLNFSTVMMFLWLALTFGLSLYQSYKLQEYIKQLAPE---TVQN------------ 245
XP_003955891 172 LNLILTGLPVLNLLLLATTKYTRERIGFVTVLVHAWTVATFGLGLLQQHKLGTYITELTPP---TTQN------------ 236
CCC71141     174 LNIILALLTIFNLLLLYSIHFTRSRISFTDNAIYIWTSLSFLVGALLDWSILNYNNSLTIQ---PYDES----------- 239
XP_001644098 171 LNMVLFILSGINLLIICCNRYINNRVGLLNILPIVWAGTSFLIGIVFEWYLLHFNRQVLKE---CASDDDDdligislgs 247
CAR26707     178 LNITLCVLTLFNLGLLYLVSYTRQRLGIAGTFTHLWAAFSFFIGVIIDWYLLSYNSQLNKPfneDEEHSGDnhrrgna-- 255
XP_003679861 181 LNMVLCLLTLFNLELIYMITYTRRRIGFMGTFTYLWAAFSFFVGIVLDWYLLDYNKQITQPfddDNFEAADnvqgrrih- 259
P53925       150 LNVTLCVLTLFNLALTYLIKYTRQRIGFVGTFTYLWTSFSFFIGAILDWYLLFYNNSINEP---LEERRIDdanistfne 226 Saccharomyces c...
XP_002553902 164 LNVVLFFMTLFNLFLTLIIGYTRRRLGFVGAFTYIWAALTFFAGAVLDWYLYYYFKEFHAAeeeIEESPSPsg------- 236
Q6CIU6       191 LNVVLCGLTLFNLLTNLLVKYIRQRIGLLGVCTYLWAAVSFAVSAVMDRYLYYFNTKFHPNnydDAEADNDensphpne- 269 Kluyveromyces l...
XP_003686100 239 sratsiqndsqineptnsnslqsiyvlpvignsqntqRHTLQEWTYIFVKVFGKLLLLMYMIFFTLNTLLSIWDLSeVtk 318
CCK71993     246 -------------------------------------KHTLKEWIKIAFRNVVKILCCGLLFLMTLNSFLFMIDTHnVan 288
XP_003955891 237 -------------------------------------KHTIVEWFKIAFRNLIKFGTFIILVLIVLTTLLNVIDIHnAl- 278
CCC71141     240 -------------------------------------KHTIKEWIFIATRNLIKILLLAQLFFLTTTNLLSTFDLHhAq- 281
XP_001644098 248 fesne------------------plsiqrlsfvrsmqSHTLTEWLYIGLRNLIKILLVVFIALFTLNTMLYAWDISvLtk 309
CAR26707     256 -------------------------------dfassgKHTLTEWIYIGVRNLVKCAILVFFVLFTLNTMLSTLDIHrVsk 304
XP_003679861 260 ------------------------------hqqetsgKHTLSEWIFIGVRNVLKVLLLVFFLLFTCNTLLSAWDIHrVtg 309
P53925       227 nhtnstenrdr-------sqygsgsptpthrsqlvqnKHTLTEWVSIGFRNTIKFLILIFFALFTLNTLLTTLDTYrLth 299 Saccharomyces c...
XP_002553902 237 ------------------------------------sRHTMKEWVSIGARNFVKCAIFVFYVFFTLNTLLYTIDVGrVtr 280
Q6CIU6       270 -----------------------------hshksirnRHTLTEWVSIGFRTTVKGVLLVFFILFTLNNVLFSLDSIlTtk 320 Kluyveromyces l...
XP_003686100 319 nlasnkqlknpENLDGFYWVDkEHTYQLHIKC 350
CCK71993     289 ---------fkDDDSQFVYADsQHSKTLHIKC 311
XP_003955891 279 ----------sYSLGTFHWTSsDHDNKLHVQC 300
CCC71141     282 -----------PPSTEFHWTDkNKVSQLHIEC 302
XP_001644098 310 nitn--iknseESYESFHWIDeAHSYKLHIKC 339
CAR26707     305 nsae--vdaeaASYNAFHWVDkAHTYKLHIEC 334
XP_003679861 310 kvad--vsteaATYDAFHWVDdNHSYKLHIRC 339
P53925       300 klp---itvqsPSYEAFHYVDaAKTYQLHITC 328 Saccharomyces cerevisiae S288C
XP_002553902 281 gvkd-vsakasASYDAFHWVDkEHTYQLHITC 311
Q6CIU6       321 qvaqvsteanaASYDAFHWVDaDHNYQIHLKC 352 Kluyveromyces lactis
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