2RP4


Conserved Protein Domain Family
P53_C
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pfam11619: P53_C 
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Transcription factor P53 - C terminal domain
This family of proteins is the C terminal domain of the transcription factor P53. While the rest of the protein is quite conserved between the different transcription factors such as p53 and p73, the C terminal domain is highly divergent. The DM-p53 structure is characterized by an additional N-terminal beta-strand and a C-terminal helix.
Links
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Statistics
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PSSM-Id: 314489
Aligned: 5 rows
Threshold Bit Score: 121.128
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2RP4_A        10 AEWNVSRTPDGDYRLAITCPNKEWLLQSIEGMIKEAAAEVLRNPNQENLRRHANKLLSLKKRAYELP 76 
XP_001954457 339 HNWDVSATDNGKYQLSITVPNKEWLLDSIEGMIKEAATQVLRSPNKDRLRSYAQSLLKLKKRAYELP 405
XP_002058352 327 ADWEVSRAIDGDYRLVIKFSNKDLLLRSIEGIIEKTAVAMIRNPQNLKLRQQTNHLMNLKKYALKLS 393
XP_002001386 325 ADWQVSRTLDGDYRLVIKCEQKDMLLQSIEGIIEKAAVASLRNPQSSKLRQHVNNLLNLKKCAQKLP 391
Q9N6D8       319 AEWNVSRTPDGDYRLAITCPNKEWLLQSIEGMIKEAAAEVLRNPNQENLRRHANKLLSLKKRAYELP 385 fruit fly
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