Conserved Protein Domain Family
Ste5_C
?
pfam12194: Ste5_C 
Protein kinase Fus3-binding
This domain family is found in eukaryotes, and is approximately 190 amino acids in length. This domain is the penultimate C terminal domain from the protein ste5 which co-catalyzes the phosphorylation of fus3 by ste7. It is involved in the MAPK pathways. This domain is the minimal scaffold domain of ste5. It binds to the mitogen activated protein kinase fus3 before it is phosphorylated.
Links
?
Statistics
?
PSSM-Id: 403425
Aligned: 14 rows
Threshold Bit Score: 259.885
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
CCK71722     648 TTASSILSLKRERADELILVIQLDFDKLKEksggiggvSDYTTIFNTFKALSLKYARLPFCVLNSAGYILKIGQVKQEFS 727 
XP_002495742 566 TNISSILSLKRERPDELVVVLQLDFEKIRTk-------NNSLVIFNSLKALVLKFPDMKICIVDSGGFVRTLGRTKDVIS 638 
CCE93185     421 TTVSSILSLKRDRPDELIVVLQWNLKETNN--------GLALDIYNNVRALSLTYRDLKVCIVNEEGRVANHALAKDFFT 492 
XP_002555644 557 TTITSLLSLKRGRPTLLALVLQLDPSRLKD--------AELIGLVNSLMALTFKIRDARLCLVDLEGGIVSQGLVREQLS 628 
Q6CKB4       499 TSISSILSIKRATPNELNLVLQLDKRKTNE--------DNIVSIKNVILALTWKFSTFNCCIVDVEGMVINCGTANDVL- 569  Kluyveromyces ...
XP_003645805 510 TRISSILSLKRKIPNDLFIVFQIDPIKLLD--------GDVNTLVNICKALSWKLETAKLCLVDKDGYLVTSCSLKLAIP 581 
Q74ZU4       514 ASINSILSLKRRHPDELCLFFQIDTAKVQA--------VDYKILANTCKAILWKFNTAKVALADSNGGIVTMSLLKDFIP 585  Eremothecium g...
CCH61485     650 TNVSLMVSLKRDCPEKMVLVLQLKDNTIPQ--------ETSRLIFNTIFAVRSRLSKMQITIVNEDAMVIYFGEFLDKLD 721 
CCD27039     642 TTISSILSLKRERPDDIIIVLQLDLNKLKLg-------NNSTTLYNSLTALNMKFPNFKICIVDSNSNVLAYGDVMKAVI 714 
CCC68477     615 TTISSILSLKRERPDDVVIVLQIDFKKIKNe-------DDYTTIYNTLKALTFKFPRLKACIVDAERNTLAIEPVADFIK 687 

CCK71722     728 NLKCVEEWIDLKPT-SKFDPKELKNILH--PEGIQKHIQLVIVSNSSMEEGMSSLLMDYRSFSAPKRRHADEIKIKVGY- 803 
XP_002495742 639 TVEDLEDAQKLSEG-NRFEPIWLKNSLY--PDTTLKGLGIAIVSNTPMDTQKSCLLKDYSCFTNEGRRRPRELKIKVGY- 714 
CCE93185     493 TSDRVLGLKDNNGT-VRFDPKWLKNTFY--PGNITANIGIAVISDISLESDKSCLLMDYKPFARVGRRRPNELKVKIGYl 569 
XP_002555644 629 VVKDLKSTVKDHNR-ARFNPADFKNEFI--WENVDK-IGIAVISNTLVESGKSCLFMDYNSFAGINRTRPHELKIHIGF- 703 
Q6CKB4       570 --NSLAGPIKSNGN-QPFSPDLLHQLWYrqKQKICKNVGVVVLSNSSMENGKSCLFSDYRIFADAGKRHPNELKIKVGF- 645  Kluyveromyces ...
XP_003645805 582 KLKGLNSLLAEADRsIKFSPADIYQQIY--GAWQRENIGVTIISNSSMETGRSALLMDYSAFCNVGKRRPNELKIKVGY- 658 
Q74ZU4       586 IFSSIDHILRRHETrRKLSPNLVYRHFY--GKERLKNVGVCIISNSAMQYGKSLLLMDYSAFCNIGKKRPNELKVKVGY- 662  Eremothecium g...
CCH61485     722 EFNKL--LVKDSSNnIKFSPSWLKKQLNl-SAGSTDNTAIAIVSEAAMKKGSSCLLMDYSPFAAKGKRIANEVKIKVGY- 797 
CCD27039     715 NAADILKCEHKNAGnQNFTPEWLKNVFY--PNCMDQNIGIIVISNTVMELDKSCLFMDYKPFTCLGRRRPNELKIKVGY- 791 
CCC68477     688 NKDELRNLKDREIG-KTFNIPWLKETLY--PSGIRQNIGIVVISNSSMENDKSVLLMDFQPFTCAGRRRPNELKLKVGY- 763 

CCK71722     804 -LNVDYSDKIDELLEINSWEFMLEALCYNFSLNFDEDDDGV 843 
XP_002495742 715 -LNLDYSDKVGELVELESWNNFLEALSYSFGLAFGDDDDDD 754 
CCE93185     570 lLNVDYSKRIEELVEVGSWNQILEALSYSFSLAFGDDDEDD 610 
XP_002555644 704 -LNVDYTDCISELVEVASAHDLLETLCYGFNLSFEEEDDNN 743 
Q6CKB4       646 -LNVDYSDNIKELVEIQDWNELLEAVAYSFNLSFDDDLDSS 685  Kluyveromyces lactis
XP_003645805 659 -LNADYSDKVYELVETDKWNDVFEVICYSFNMAFGQDALTD 698 
Q74ZU4       663 -LNTDYSDQVFELVETGGWGDVLEVVCYSFNMAFGQDDYSD 702  Eremothecium gossypii
CCH61485     798 -LNVDYTDQITELVEVGGWKFVLEMLCYSFSLNFEDDDDES 837 
CCD27039     792 -LNVDYSDEINELVEIESWNYLLETLCYSMSLNFDDEDDEN 831 
CCC68477     764 -LNVDYSEKVNELVEIESWCSLLETLCYSLTLNFDDDGDTY 803
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap