Conserved Protein Domain Family
STAT1_TAZ2bind
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pfam12162: STAT1_TAZ2bind 
STAT1 TAZ2 binding domain
This domain family is found in eukaryotes, and is approximately 20 amino acids in length, and the family is found in association with pfam02865, pfam00017, pfam01017, pfam02864. This domain is the C terminal domain of STAT1. This domain binds selectively to the TAZ2 domain of CRB (CREB-binding protein). In this process it becomes a transcriptional activator and can initiate transcription of certain genes.
Links
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Statistics
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PSSM-Id: 432372
Aligned: 6 rows
Threshold Bit Score: 40.0643
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_012826050 714 SRLQttEFLLPMSPDEYAEVARLVG 738
XP_003207478 743 SRLQspENLLPMSPEEFDEVSRMVD 767
XP_015214636 728 SRLQstETMLPLSPEDFGELTRIIN 752
Q6P943       712 QEYN--ENLMPMSPEVYGELERMNR 734 zebrafish
XP_005452362 713 SRLQ--DNMMPMSPDDYKALEQYVS 735
AAL09414     712 SKLQ--DNMMPMSPDDYNALRQLVT 734
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