Conserved Protein Domain Family
Jiraiya

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pfam15038: Jiraiya 
Jiraiya
Jiraiya inhibits bone morphogenetic protein (BMP) signaling during embryogenesis. The human member of this family is TMEM221.
Statistics
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PSSM-Id: 464461
Aligned: 15 rows
Threshold Bit Score: 119.334
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_971722    113 LVSLGLLCLVSLLLALLSLIFLLKIsp----------------------vtASDIRELLr--aEQ-------LTVITAEE 161
EFX87633     121 LTSLGLLCLLSLMMALLGLIFLLKMs------------------------pPPDAIHFL----DQ-------VRIVSPDE 165
XP_015781136 260 LSSLALMCLLSLLMAFLALFFLQRTgpiitipedlkpnelplspgtnspltKDKSTVNVf--sQS-------RIVVNTRE 330
EKC40945     109 IHSLAILCLAASVILVLDIYVFLMG--------------------------TGDVPEGGf--rNG-------SLLSSVKQ 153
XP_001892260  79 LLVLALMSIVSILFAFTSLLSLLSI--------------------------QWRTTTAEs--sDL-------ATDGSLMV 123
XP_003432946  10 LAAMTLLGIPAAVLAALGAQLLFQL--------------------------QAGRAELRglradglgpelgggpgLPEDA 63 
XP_003201087  10 LVILAFLGILSSIMAVLSVILIFQL--------------------------QTQQAVIKds-----------pTFVPKDI 52 
XP_005479043  10 LIVLSLLGILSAIMSVLSVILIFQL--------------------------QSQQTAVKesppST-------SSVIPAHV 56 
1_pfamImport   1 LMVLSLLGILAAVMSVLSVLLIFQL--------------------------QARQAVGKesppGT-------SAVIPGYI 47 
XP_014345954  10 LTVLVLFGLLAALMAVLSVILIFQL--------------------------QSNQTEIKds----------spSRFSAEA 53 
XP_971722    162 YVVVYEVTLALCALTLSLNLCCLLVCAIQFLFAVKLVKSPHg-----GNDRTNKYLQKSSVSRVCAVGGFFISIPVFLTG 236
EFX87633     166 AHSVYEVSLALCSLAMTLDVCCCLVCATQLLFAARLITASTcsssnsSRDRIKKFLRDSAVTRICAVAGFFVSIPVFLTD 245
XP_015781136 331 YVRVFQISVSLSTLTISLNLCCLFVCCIQFLSAVKLLKTPQ------GTKRTQQFLKKTSHVRITAIGAFLLSIPIFFTG 404
EKC40945     154 YEDVTEVFTAFSTLVMILSSNCVLVCSMQCFIASKVSKTID------GPERAMKYFRECSSSRLIAVVGFFISFPVFLIT 227
XP_001892260 124 RNMMYEIASSLSLIAVTTSISTFLLSTLQLFFALKMLKTNPt-----SIKRVLSFLSGGRFLRCIIYTAWFFAVLFFIVG 198
XP_003432946  64 AGALLPLAAALAALALVLGLTCLLLAALCGHLGAELARG-P------GPGRSDWFLYDCRLLRHVALGVFCCGVSVYLAA 136
XP_003201087  53 TAVLLPVSTVLSALSLTLNLSSVVVCLLHSYFATEICRGEP------DTQRADWFLMDSRAVRHVTIGLFCLGVSVYLAA 126
XP_005479043  57 WAVLLPVATVLSALSLTLNLSSVVVCLLHSYFSTEVCRGEQ------DTERADWFLLDSRAVRHVAIGLFCLGVSVYLIA 130
1_pfamImport  48 WSVLPPVCAVLSALSLSLHSGSVVVCLLHGYFSTEVCKGEQ------DADRADWFLLDSRAVRHVAIGLFCLGVSVYLAA 121
XP_014345954  54 IRILLPVATVLTALALTLNLSCVIVCLLHSCFTTEVCRGDS------EPDRSDWFLLDSRTIRHVAIGLFCLGISVYLAA 127
XP_971722    237 IILYTFIQFHSTPAIVTSVFIGLG-------IIFCGCAMVHNVFIWQREKTNAVKEL 286
EFX87633     246 IVLYTIIQFPSTPAITTSIVISVG-------IVLCGCAMLHNIVVWQRYKGSNSGSM 295
XP_015781136 405 VILFTFINFDETPALITSIIIGIG-------IVFCGLASVQNVYLWQAEKTKASKEM 454
EKC40945     228 LMLCVVLRLKRTPALTAAVVLIIG-------TILGLLCMVQNIYHWYDEMSSASRGL 277
XP_001892260 199 SMLQWMLL----PGRVGTISRGVGaafgiasTALCTAGLIHCIYVWCSNDDKEVQES 251
XP_003432946 137 LSIYALLLFEIETGAAAASILGVG-------ALVLVAALTHTLLRAARATRRSLHEL 186
XP_003201087 127 MSIYMVLVFEVETGIASVCVLSSG-------VLVLLLIIIHSLIRAARAAKHYRTDH 176
XP_005479043 131 MSIFMLLIFEMETGIASACVLSSG-------ILILLVAVIHALVKASHTGKHYHSDH 180
1_pfamImport 122 MAIFMLLVFEVETGIAGACTLCSG-------IPVILVVVIHALVKAALGAKRHRGNH 171
XP_014345954 128 LSIYMLLLFEIESGIASACILSSG-------VIVLLVTVLHSLIKASHAVQRSRAEL 177
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