Conserved Protein Domain Family
DUF4682

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pfam15733: DUF4682 
Domain of unknown function (DUF4682)
This domain family is found in eukaryotes, and is typically between 152 and 183 amino acids in length. The family is found in association with pfam00566. There is a conserved NHLL sequence motif.
Statistics
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PSSM-Id: 464830
Aligned: 32 rows
Threshold Bit Score: 77.0278
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_005475924         662 IHALKKQYARIKRRQQQQAMQLYIrtgpgpvaptspgvlqgasskqsgstteqhgddkcPATRVLASQLNPsssVINHLL 741 
XP_002599666         611 ITALKKQYMRIRQKQQ-RTHLIYPkqgn---------------------------enksTSTHKFSATARDtpiAMNHLY 662 
EFA12119             511 ISALKKQYAKLKQRQR-QAHIIFS-------------------------------------AAISRQPPPSapvAMNHLL 552 
Q7Q0H0               365 ISLLKKQYDKLRERQR-QAHIILTaa--------------------------------vARQPANPSP-NAgtlQVNQLL 410  Anophe...
EDS39028             426 ISLLKKQYDKLRERQR-QAHIILTa----------------------------------AVARQPPANPQSnslQVNQLL 470 
OWR46947             574 IGALKRQYARLRERQR-QAHVILAaa--------------------------------cARHAAVGVPTSPtslTVNNLL 620 
XP_002053045         551 ISLLKKQYDRLRERQK-QAHVILTt---------------------------------aCTTATSTRQTPSnqlPVNQLL 596 
WGS:AAQB:GK22633-PC  445 ISLLKKQYDRLRERQK-QAHVILTt---------------------------------aCSTATRQTPSAQssvPVNQLL 490 
XP_030178991         360 INALKRQYSRIKKKQQQQVHQVYIragsteekdhgsl----------lgtknqalddkgPVTSILPSQVNNs-pVINHLL 428  Canada...
XP_005989516         487 INALKRQYSRIKRRQQQQAHHVYItagseedltpgik----------qdprekmnndkgPVTSLLPSQVNQs-pVINHLL 555  coelac...
XP_005475924         742 LGRK-PRGGARGYRPTsattstlpgarpsslfQSPVPPGSPARQRCsslaSNSTGSPgssrggggspW---RTHVRQHRR 817 
XP_002599666         663 VARKiASIQGKTKRIKgpe-----------irPAPQKGRHPTDGRRegvkKESGNEDssggveiqiqW---TSSM---GR 725 
EFA12119             553 LGKSaLVPAKRLGPPKvs------------ipPARTTPPSTLL------------------------W---KDAPKTTSD 593 
Q7Q0H0               411 VGKN-ALLSAKGKRLGppqg---------avpPVRSGSKSSSKQSG----KQSTGPSrspkpvetlhW---KDMDETKQR 473  Anophe...
EDS39028             471 VGKN-AILSNKGKRLGp---------------PQGAVPPIRAPKSSkqgkSGAPKSPkpae---tlhW---KDMDEKQRR 528 
OWR46947             621 LGKS-AIVSSRGRRLGpppg---------avpPSRQTTNSNEKFER----YSSRSSNdt------isWeeeKTRKTLNRR 680 
XP_002053045         597 LGRP-AIITNKGKRVGaplg---------aipPARKPSLPTVLHSK----PPASGERqlrrg-etllW---RDTDATRQR 658 
WGS:AAQB:GK22633-PC  491 QGRH-AIVTNRGKRVSaplg---------aipPARKPSLPAVLHGN----GKPMMGEkqlrrgetllW---RDTDTSRRR 553 
XP_030178991         429 LGKK-VKMSNRPAKNAvih-----------ipGHTGGRTSPVPYEDl---KTKLNSP----------W---RTHIRVHKK 480  Canada...
XP_005989516         556 LGKK-IKSTNRAARNTi--------------vHVPGSKASQIPHEDl---KTKLNSP----------W---RTHIRVHRK 604  coelac...
XP_005475924         818 NIARARAQLGFGDSEDREDE-EEKEKRES 845 
XP_002599666         726 STTERRSSEHSVESSVGSEGsENTGSKER 754 
EFA12119             594 SSSSSDTELCDDPSEGSSDE-QDEEIKSQ 621 
Q7Q0H0               474 RNSLKWKDLPKDGATKKPPD-EGSKPDSS 501  Anopheles gambiae str. PEST
EDS39028             529 GSLKWREMQKDGKKPTIKDD-SDIAKPEs 556 
OWR46947             681 NSVKWKDIKKDTALEFARK--PSIDLDES 707 
XP_002053045         659 RDSLTWKEIKADRAAMLRDE-ADAKMVKS 686 
WGS:AAQB:GK22633-PC  554 RDSLTWKEIKADRAAMLREGvDSSSLKTQ 582 
XP_030178991         481 NMTRTKSQLGCGDTVGLIEE-QNEGCKTK 508  Canada lynx
XP_005989516         605 NIARAKGQLGYGDTIGLIEN-QSDRFKDG 632  coelacanth
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