Conserved Protein Domain Family
TLV_coat

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pfam00429: TLV_coat 
ENV polyprotein (coat polyprotein)
Statistics
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PSSM-Id: 306850
Aligned: 16 rows
Threshold Bit Score: 357.568
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P31791         8 VFLWVLTSLGAgigakIVKEGNPHQVYTLTWQIYSqsgevvwevqgnhalnTWWPALTPDFCQLAA-GLDTWDIPDRSPK 86  Feline endogeno...
P03386        21 IVLLILGGVNP-----VTLGNSPHQVFNLTWEVTNgdretvwaitgnhplwTWWPDLTPDLCMLALhGPSYWGLEYRAPF 95  AKR (endogenous...
P08360        21 GVLGILFVTGG-----LASRDNPHQVYNITWEVTNgeqdtvwavtgnhplwTWWPDLTPDLCMLALhGPTHWGLDNHPPY 95  Cas-Br-E murine...
P07575         8 IWSLVILSQISq---vQAGFGDPREALAEIQQKHG------------------KP------CDCAGg-YVS-SPPINSLT 58  Mason-Pfizer mo...
P10269         8 IFLYNLVLv-------YAGFDDPRKAIELVQKRYG------------------RP------CDCSGg-QVS-EPPSDRVS 54  Baboon endogeno...
P21412         2 LCILILLLHPRlcpvtKGGLGKPSG--DIYTALFG------------------AP------CDCKGgTQTNNYATPTYTQ 55  Squirrel monkey...
P03399        21 LILLVVWW----------GFGTTAEGHPL-QQLWE------------------LP------CDCSGg-YVSPDLPITPTP 64  Reticuloendothe...
P31796        21 LILLVAWW----------GFGTTAEGYPL-QQLWE------------------LP------CDCSGg-YVS-SIPTYYTY 63  Avian spleen ne...
1_pfamImport   1 TLTLLALC---------------------------------------------RPI-QTWRCSLSLgNQQWMTAYNQEAK 34 
P03383         5 FFLLLFSL-------------------------------------------THFPLAQQSRCTLTIgISSYHSSPCSPTQ 41  Human T-lymphot...
P31791        87 NLETSMEGTSQQLTPQG----------------CSKPWKR------CALTERDFYVCPRDNRDRa-TAHRCGGYEEYFC- 142 Feline endogeno...
P03386        96 SPPPGPPCCSGSSDSTPgcsrdceepltsytprCNTAWNRlklskvTHAHNGGFYVCPGPHRPR--WARSCGGPESFYC- 172 AKR (endogenous...
P08360        96 SSPPGPPCCSGDAGAVSgcardcdepltsysprCNTAWNRlklarvTHAPKEGFYICPGSHRPR--WARSCGGLDAYYC- 172 Cas-Br-E murine...
P07575        59 TVS--CSTHTAYSVTNSlk------------wqCVSTP--------TTPSNTHIGSCPGECNTIsyDSVH----ASCYN- 111 Mason-Pfizer mo...
P10269        55 QVT--CSGKTAYLMPDQrw-------------kCKSIPK-------DTSPSGPLQECPCNSYQ---SSVH----SSCYT- 104 Baboon endogeno...
P21412        56 VTD--CGDKNAYLTYDTnwngvs-----spkwlCVRKPPS------IPVINGRPGPCPSECTNNikSQMH----SSCYS- 117 Squirrel monkey...
P03399        65 SIA--VASPLPDLRVWLqgswgwgg-gfrqqweCVFKPKI------IPSVQEQPGPC--ECLTIa-TQMH----STCYE- 127 Reticuloendothe...
P31796        64 SLD--CGGSTAYLTYGSgtgswswgggfkqqweCVFKPKI------IPSVQGQPGPCPSECLQIa-TQMH----STCYE- 129 Avian spleen ne...
1_pfamImport  35 FSISIDQILEAHNqs----------------pfCAKSPRYtl---dSVNGYPKIYWPPPQGRRRfgARA-----MVTYD- 89 
P03383        42 PVCTWNLDLNSLTTDQRlh------------ppCPNLITYs-----GFHKTYSLYLFPHWIKKP--NRQGLGYYSPSYNd 102 Human T-lymphot...
P31791       143 -SAWGCETTG-----DAYWQPTSTWDLITITRNYTkpdscddrvereRKTSRHWRDPLSLPLKITFTDSGKRAlgwqTGY 216 Feline endogeno...
P03386       173 -ASWGCETTG-----RASWKPSSSWDYITVSNNLTs----------dQATPVCKGNEWCNSLTIRFTSFGKQAtswvTGH 236 AKR (endogenous...
P08360       173 -ASWGCETTG-----RAAWNPTSSWDYITVSNNLTs----------sQATKACKNNGWCNPLVIRFTGPGKRAtswtTGH 236 Cas-Br-E murine...
P07575       112 -HYQQCNIGN-----KTYLTA-------TITGDRTpa---------iGDGNVPTVLGTSHNLITAGCPNGKKG----QVV 165 Mason-Pfizer mo...
P10269       105 -SYQQCRSGN-----KTYYTA-------TLLKTQT------------GGTSDVQVLGSTNKLIQSPC-NGIKG----QSI 154 Baboon endogeno...
P21412       118 -SFSQCTQGN-----NTYFTA-------ILQRTKSt-----------SETNPVTSGLQPHGVLQAGC-DGTVG----KSV 168 Squirrel monkey...
P03399       128 -KAQECTLLG-----KTYFTA-------ILQKTKL-----------------GSYEDGPNKLLQASC-TGIW-----ETS 171 Reticuloendothe...
P31796       130 -KTQECTLLG-----KTYFTA-------ILQKTKL-----------------GSYEDGPNKLIQASC-TGTVG----KPV 174 Avian spleen ne...
1_pfamImport  90 -CEPRCPYVGadrfdCPHWDNASQADQGSFYVNHQ-------------------------ILFLHLKQCHGIF-----TL 138
P03383       103 pCSLQCPYLG-----CQAWTSAYTGPVSSPSWKFH-------------SDVNFTQEVSQVSLRLHFSKCGSSM-----TL 159 Human T-lymphot...
P31791       217 TWGLR--WYLP-GKDRGIILKIKLKIDTItqt--vgpNLVLADQkTPVQLAIPVQPPRAPtqtprvnpvnstlspslgyp 291 Feline endogeno...
P03386       237 WWGLR--LYVS-GHDPGLIFGIRLKITDSgprvpigpNPVLSDR-RPPSRPRPTRSPPPSnstpt--------------- 297 AKR (endogenous...
P08360       237 FWGLR--LYIS-GHDPGLTFGIRLKVTDLgprvpigpNPVLSDQ-RPPSRPVPARPPPPSasp----------------- 295 Cas-Br-E murine...
P07575       166 CWNSRpsVHISdGGGPQDKARDIIVNKKF--------EELHRSL-FPELSYHPLALPEARg------------------- 217 Mason-Pfizer mo...
P10269       155 CWSTTapIHVSdGGGPLDTTRIKSVQRKL--------EEIHKAL-YPELQYHPLAIPKVRd------------------- 206 Baboon endogeno...
P21412       169 CWNQQapIHVSdGGGPQDAVRELYVQKQI--------ELVIQSQ-FPKLSYHPLARSKPR-------------------- 219 Squirrel monkey...
P03399       172 MLGPRcpCVCLdGGGPTDRFG-RICAEGL--------EEIIRHS-YPSVQYHPLALPRPR-------------------- 221 Reticuloendothe...
P31796       175 CWDPVapVYVSdGGGPTDMIREESVRERL--------EEIIRHS-YPSVQYHPLALPRSR-------------------- 225 Avian spleen ne...
1_pfamImport 139 TWEIW-------GYDPLITFSLH----------------------KIPDPPQPDFPQLNS-------------------- 169
P03383       160 LVDAP-------GYDPLWFIT------------------------SEPTQPPPTSPPLVH-------------------- 188 Human T-lymphot...
P31791       292 apapgprppyPTSPS--RPGTGDRLLNLVQGVYLTLNLTAPNQTQDCWLCLTAK--PPYYQGVAIIGNFTNHTNAPLr-- 365 Feline endogeno...
P03386       298 -----etpltLPEPP--PAGVENRLLNLVKGAYQALNLTSPDKTQECWLCLVSG--PPYYEGVAVLGTYSNHTSAPAn-- 366 AKR (endogenous...
P08360       296 --------stPTIPP--QQGTGDRLLNLVQGAYLTLNMTDPTRTQECWLCLVSE--PPYYEGVAVLREYTSHETAPAn-- 361 Cas-Br-E murine...
P07575       218 -----------------KEKIDAHTLDLLATVHSLLNASQPSLAEDCWLCLQSG--DPVPLALPYNDTLCSNFACLSnhs 278 Mason-Pfizer mo...
P10269       207 -----------------NLMVDAQTLNILNATYNLLLMSNTSLVDDCWLCLKLG--PPTPLAIP-NFLLSYVTRSSDnis 266 Baboon endogeno...
P21412       220 -----------------GPDIDAQMLDILSATHQALNISNPSLAQNCWLCLNQG--TSMPLAFPVNISSFNASQNN---- 276 Squirrel monkey...
P03399       222 -----------------GVDLDPQTSDILEATHQVLNATNPQLAENCWLCMTLG--TQSPQ--PSRRMAMSLSMEIA--- 277 Reticuloendothe...
P31796       226 -----------------GVDLDPQTSDILEATHQVLNATNPKLAENCWLCMTLG--TPIPAAIPTNGNVTLDGN------ 280 Avian spleen ne...
1_pfamImport 170 ----------------------DWVPSVRSWA-LLLNQTARAFP-DCAICWEPS--PPW----APEILVYNKTI------ 213
P03383       189 ----------DSDLEhvLTPSTSWTTKILKFIQLTLQSTNYS----CMVCVDRSslSSWHVLYTPNISIPQQTSSR---- 250 Human T-lymphot...
P31791       366 CSTTPRHGLTLTEVTGYGLCIG-------KIPPSHQNLCS------------QTVpSVGQGPYYLTAPNGTYWVCNTGLT 426 Feline endogeno...
P03386       367 CSVASQHKLTLSEVTGQGLCIG-------AVPKTHQVLCN------------TTQ-KTSDGSYYLAAPTGTTWACSTGLT 426 AKR (endogenous...
P08360       362 CSSGSQHKLTLSEVTGQGRCLG-------TVPKTHQALCN------------RTE-PTVSGSNYLVAPEGTLWACSTGLT 421 Cas-Br-E murine...
P07575       279 CPLTPPFLVQPFNFTDSNCLYAhyqnnsfDIDVGLASFTNcs--------syYNVsTASKPSNSLCAPNSSVFVCGNNKA 350 Mason-Pfizer mo...
P10269       267 CLIIPPLLVQPMQFSNSSCLFSpsynsteEIDLGHVAFSNct--------siTNV------TGPICAVNGSVFLCGNNMA 332 Baboon endogeno...
P21412       277 CTPSLPFRVQPMPSQVYPCFFKgaqnnsfDIPVGVANFVNcs--------------sSSNHSEALCPGPGQAFVCGNNLA 342 Squirrel monkey...
P03399       278 VLASLSGATHRVNRCQLLC--Read-nrtGIPVGYVHFTNctsiqesltrrvIYEiLRDYVLHRV------MYLCVEQHA 348 Reticuloendothe...
P31796       281 CSLSLPFGCNPPGSIDVSCYAGead-nrtGIPVGYVHFTNctsi-----qevTNEtSQMGNLTRLCPPPGHVFVCGNNMA 354 Avian spleen ne...
1_pfamImport 214 SSSGPGLAL----------------------PDAQIFWVN-----------------------------TSSFNTTQGWH 242
P03383       251 TILFPSLAL----------------------PAPP-SQPF-------------------------------------PWT 270 Human T-lymphot...
P31791       427 PCISLQILNDTADYCILIELWPKIFYHDSE---YIYGHYEPGGRFRRD-PVSLTVALLLGGLtmgSLAAGIGTGTAAL-I 501 Feline endogeno...
P03386       427 PCISTTILDLTTDYCVLVELWPRVTYHSPS---YVYHQFERRAKYKRE-PVSLTLALLLGGLtmgGIAAGVGTGTTAL-V 501 AKR (endogenous...
P08360       422 PCLSTTVLNLTTDYCVLVELWPKVTYHSPD---YVYTQFEPGARFRRE-PVSLTLALLPEGLtmgGIAAGVGTGTTAL-V 496 Cas-Br-E murine...
P07575       351 ---YTYLPTNWTGSCVLATLLPDIDIIPGSepvPIPAIDHFLGKAKR----AIQLIPLFVGL---GITTAVSTGAAGLgV 420 Mason-Pfizer mo...
P10269       333 ---YTYLPTNWTGLCVLATLLPDIDIIPGDepvPIPAIDHFIYRPKR----AIQFIPLLAGL---GITAAFTTGATGLgV 402 Baboon endogeno...
P21412       343 ---FTALPANWTGSCVLAALLPDIDIISGDdpvPIPTFDYIAGRQKR----AVTLIPLLVGL---GVSTAVATGTAGLgV 412 Squirrel monkey...
P03399       349 ---YTALPNKWIGLCILASIVPDMSIIPGEepiPLPSIEYTAGRHKR----AVQFIPLLVGL---GITGATLAGGTGLgV 418 Reticuloendothe...
P31796       355 ---YTALPNKWIGLCILASIVPDISIISGEepiPLPSIEYTARRHKR----AVQFIPLLVGL---GISGATLAGGTGLgV 424 Avian spleen ne...
1_pfamImport 243 HPSQRLLFNVSQG---NALLLPPISLVNLS-----TASSAPPTRVRRSpVAALTLGLAL------------SVGLTGInV 302
P03383       271 HCYQPRLQAITTDNCNNSIILPPFSLAPVP---------PPATRRRRAvPIAVWLVSAL------AAGTGIAGGVTGS-L 334 Human T-lymphot...
P31791       502 E-----TNQFKQLQIAMHSDIQALEESISALERSLISLSEVVLQNRRGLDLLFLQEG--GLCAALKEECCFYADHTGIVR 574 Feline endogeno...
P03386       502 A-----TQQFQQLQAAMHDDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEG--GLCAALKEECCFYADHTGLVR 574 AKR (endogenous...
P08360       497 A-----TQQFQQLQAAMHNDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEG--GLCAALKEECCFYADHTGLVR 569 Cas-Br-E murine...
P07575       421 S-----ITQYTKLSHQLISDVQAISSTIQDLQDQVDSLAEVVLQNRRGLDLLTAEQG--GICLALQEKCCFYANKSGIVR 493 Mason-Pfizer mo...
P10269       403 S-----VTQYTKLSNQLISDVQILSSTIQDLQDQVDSLAEVVLQNRRGLDLLTAEQG--GICLALQEKCCFYVNKSGIVR 475 Baboon endogeno...
P21412       413 A-----VQSYTKLSHQLINDVQALSSTINDLQDQLDSLAEVVLQNRRGLDLLTAEQG--GICLALQERCCFYANKSGIVR 485 Squirrel monkey...
P03399       419 S-----VHTYHKLSNQLIEDVQALSGTINDLQDQIDSLAEVVLQNRRGLDLLTAEQG--GICLALQEKCCFYANKSGIVR 491 Reticuloendothe...
P31796       425 S-----VHTYHKLSNQLIEDVQALSGTINDLQDQIDSLAEVVLQNRRGLDLLTAEQG--GICLALQEKCCFYANKSGIVR 497 Avian spleen ne...
1_pfamImport 303 AvsalsHQRLTSLIHVLEQDQQRLITAINQTHYNLLNVASVVAQNRRGLDWLYIRLGfqSLCPTINEPCCFL----RIQN 378
P03383       335 S-----LASSKSLLLEVDKDISHLTQAIVKNHQNILRVAQYAAQNRRGLDLLFWEQG--GLCKAIQEQCCFL----NISN 403 Human T-lymphot...
P31791       575 DSMAKLRERFKQRQKLFESQQGWFEGWYNKSPWFTTLVSSLMVPLILLLLILMFGPCILN----HLLQFIR 641 Feline endogenous virus ...
P03386       575 DSMAKLRERLSQRQKLFESQQGWFEGLFNKSPWFTTLISTIMGPLIILLLILLFGPCILN----RLVQFIK 641 AKR (endogenous) murine ...
P08360       570 DSMAKLRERLNQRQKLFESGQGWFEGLFNRSPWFTTLISTIMGPLIVLLLILLFGPCILN----RLVQFVK 636 Cas-Br-E murine leukemia...
P07575       494 DKIKNLQDDLERRRRQLIDNPFW-TSFHGFLPYVMPLL----GPLLCLLLVLSFGPIIFN----KLMTFIK 555 Mason-Pfizer monkey virus
P10269       476 DKIKTLQEELERRRKDLASNPLW-TGLQGLLPYLLPFL----GPLLTLLLLLTIGPCIFN----RLTAFIN 537 Baboon endogenous virus ...
P21412       486 DKIKNLQEDLEKRRKALADNLFL-TGLNGLLPYLLPFL----GPLFAIILFFSFAPWILR----RVTALIR 547 Squirrel monkey retrovirus
P03399       492 DKIRKLQEDLLARKRALYDNPLW-NGLNGFLPYLLPSL----GPLFGLILFLTLGPCIRK----TLTRIIH 553 Reticuloendotheliosis virus
P31796       498 DKIRKLQEDLIERKRALYDNPLW-SGLNGFLPYLLPLL----GPLFGLILFLTLGPCIMK----TLTRIIH 559 Avian spleen necrosis virus
1_pfamImport 379 DSIIRLGDLQPLSQRVSTDWQWPWNWDLGLTAWVRETIHSVLSLFLLALFLLFLAPCLIKcltsRLLKLLR 449
P03383       404 THVSVLQERPPLEKRVITGWGL--NWDLGLSQWAREALQTGITILALLLLVILFGPCILR----QIQALPQ 468 Human T-lymphotropic vir...
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