Conserved Protein Domain Family
TFP_LU_ECD_Ly6G5c
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cd23545: TFP_LU_ECD_Ly6G5c 
extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G5c (Ly6G5c) and similar proteins
Ly6G5c is a glycosylated, potentially secreted protein which could act as ligand for other cell-surface receptors and could thus potentially have a role in cell signaling. Ly6G5c may have a role in hematopoietic cell differentiation. It contains an extracellular domain (ECD) which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).
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Statistics
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PSSM-Id: 467075
Aligned: 4 rows
Threshold Bit Score: 128.456
Created: 28-Nov-2018
Updated: 27-Apr-2023
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q5SRR4        58 KYLRCYRCLLETKElGCLLGSDICLtpaGSSCITLHKKnssg--------------------------------sdvMVS 105 human
Q8K1T5        57 KYLNCYRCLLETEElGCLLGSDTCLtplGSSCVTLHIKnssg--------------------------------fnvMVS 104 house mouse
XP_020829745  31 KLLRCYRCILETKElGCVLGSDICLtakGGGCLTTIIHcgsk--------------------------------devIVS 78  koala
XP_027244495  40 KYLHCYFCLLETQExGCLLGLDVCLx--GSSCIILHIKngtesrtcawvlphitvlpssavetipllqpnlqytpapVHG 117 Chinese hamster

Q5SRR4       106 DCRSKEQMsdCSNTRTSPVsGFWIFSQYCFLDFCNDPQNR 145 human
Q8K1T5       105 DCYSKEQMvhCSYTRASPVfGFWIFYQCCFLDFCNNPDNR 144 house mouse
XP_020829745  79 DCRAKDRLseCSLSLASPVpGLWVSSRCCLEPLCNSPPLR 118 koala
XP_027244495 118 NCRSREQVkaCSHAPAFPAfGFWIVYQHCFXDFCNNPTNR 157 Chinese hamster
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