Conserved Protein Domain Family
DUF5587

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pfam17825: DUF5587 
Family of unknown function (DUF5587)
This is a family of unknown function found in chordata.
Statistics
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PSSM-Id: 465523
Aligned: 6 rows
Threshold Bit Score: 2568.74
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5VXU9          1 MTDTSVLDQWKASFFVEDFLEKKTITRMVtqINCEFEEVVPSSNPDSQIEVEEVSLYTHMDYNEVFTPVSCLEKCSALQN 80   human
A2ALV5         66 MEDNSVLEQWRTRFCVEGVPEKKTVTGVM--INGTFEEIVPSSNPNSPPGIENDKLFPSKDYVDDFIPVKCSLYYPGVKA 143  house mouse
XP_001490201    2 TDISVLDQWKASLFMEDFLEKKTVTGMVTqiNCEFEEIVPSSNPNSQIEVEEASLYTHKDYSEVFTCVNCLEKCPGLQAQ 81  
2_pfamImport    1 MTDTSVLDQWKASLFVEEFLEKKTVTGMMteIDYGFEEIVPSSNPNSPIEIEEASLYTDTDYNEVFTPIGGLEKCSTLQT 80  
XP_005329767    1 MTDSSILDQWKAGFFVEDFLEKKTVTGMVyqVNGEFEEIVPSSNPNSQTEVEEESFYTHKDYNEVFTPVKCSEKCPALQA 80   thirteen-line...
XP_023609036    1 MTDSSILDQWKASLIGEEFHEKKTVTGMMtqINCEFEEIVPSSNPNSPIEVDEAILHTQKDYTEVFTPISCSEKCPAFQA 80   little brown bat
Q5VXU9         81 QNQDLFIdDKGILFVSS----RKHLPTLPTLLSRLKLFLVKDPLLDFKGQIFTEANFsRECFSLQETLEAFVKeDFCMDK 156  human
A2ALV5        144 EHQGLLI-DEEMIFMNKa--mDNHLPTVNGLLSRLKLYLVKDPFLDFKEELSGKDNF-TEYFSVQECSEPFVR-DFHMAE 218  house mouse
XP_001490201   82 NQDLSIDdEEIIFVNNLmaykSHLPTLHTLLSRLKLFLVKDPLLDFQGQIFTEANFFrECFSFQRDLKDFMKEdFYMDKE 161 
2_pfamImport   81 QNKDLYI-DEEILFVNNlmtyKSQLPTVHTLLSRLKPFLIKDPILDFKEQIFTEANFfREHFSFQGDLKSLVKeDFYMHK 159 
XP_005329767   81 QNQDLFIdDEELIFINDlatlKSQLPTLKTLLSRLKLFLIKDPLLDFKEQIFKEANLfRKYFSFQEDLDVCVKeDFYMDK 160  thirteen-line...
XP_023609036   81 QNQDLFFdDEEIIFTNNlmtyKSYLPTLDTLLSRLKLFLIKDPLLDIKEQIFTDADFfRECFSFQGDLKDLMKeDFYVDK 160  little brown bat
Q5VXU9        157 VNFCQEKLEdticlnepSSFLIEYEfLIPPSLKPEIDIPSLSELKELLNPVPEIINYVDEKe--KLFERDLTNKHGIeDI 234  human
A2ALV5        219 ETFCKKKLP--------SVFPSGFKsLISTNPKQEILILPPSKLKKPLNSIPKIMDSVDES---ECFKGDITSKHEF-DT 286  house mouse
XP_001490201  162 NFCQEKLEDtvsl-netPSILADCEfLVSTSLKQEVGIPSLSELKESLNLMPEVINYVDESg--NLFERELITKHGI-DI 237 
2_pfamImport  160 ENFCQEKLEd------tPSILSECEfLISTSSKQEADIPSLSELKESLNLVPEIINYADEN---ELFKRDLTAKHGS-DI 229 
XP_005329767  161 ENFCQEKLDdevglnepPTFPSEFEsLISSSFKQEIDIQPPSELKESLAIVPEIKNCIDENe--KKFKRDLTTKHRI-DI 237  thirteen-line...
XP_023609036  161 ENFCQEKLEdtvg-lnePSVFSECE-LIAPNLDQEVGIPSPSELKESLHLVPEIITYEDENeyeKLFKRDPTTKHAI-DT 237  little brown bat
Q5VXU9        235 GDIKFSSTEILTIQSQSEPeECSKPGELEMPLTPLFLTCQHSSVNSLRTELQTFPLSPVCKINLLTAEESANEYYMMWQL 314  human
A2ALV5        287 EDIKCNSTENLTFASLCEP-ECSEPGDLEMPPTHLILPRQHSAVSSLHMGFQTFPFSATCKINLLSAGESANKYCMLWQL 365  house mouse
XP_001490201  238 EDRKCSSTEILAIQSQSEP-EHSEPVELEMPLSPLLLTNQCSSVSSLCTGLQTFPFSPVCKNSLLTAEESANKYCMVRQL 316 
2_pfamImport  230 EDIKCSSTEILAIQSHCEP-EYSEPVELEMPLTHLHLTNQPSSVTSLCTRLQTFPFSPVCKINLLSAEESAHKYWMMWQL 308 
XP_005329767  238 DDIKRSSTEISGIQSQSEP-ECNKPGELEIPLTRIHLTSQHSSVNSLCTGLETFPFSSVCKISFLITSESANKYCMVWQL 316  thirteen-line...
XP_023609036  238 EDIKCSSTEILAIPSQCKP-EHHKPeeleMPLPPLHLANQQSSVNSLCTGLQTFPSSPACKISLLTAEKSANEDCTVWQS 316  little brown bat
Q5VXU9        315 ERCRSPLNPFLLTVPRIQEPHSQYSVTDLKKIFSVKEESLVINLEKAEWWKQAGLNLKMMETLEHLNTYLCHDNLSSNDT 394  human
A2ALV5        366 GGCRNSWVSFLLTVPRFQEPSSQYSLADMRNIFSVKGDSLVINPAKAKGWRQARLHPIMAETLAHLKAYLCHNGLSSQET 445  house mouse
XP_001490201  317 ESYRSSLNPFLLSVPRTEEPNSQYSATDLKKILSIEEESLVVNPVSAEWWKQAGLNLIVTETLEHLNTHLSHDDLSSDDT 396 
2_pfamImport  309 ESCRSSLNPFLFTVPRTEEPRSQCSVTDLKKIFSIEEESLVVNPISTEWWKEGGLNLIETETLELLNTYLSGNDLSSSDT 388 
XP_005329767  317 ESCKSSLNSFLHTALRIQEPNSQYSITDFKKIFSIKEESLAINPVKAEWWKPASLNLAIGETLEHLNTYVCHDDQPSNDT 396  thirteen-line...
XP_023609036  317 ESCRSFQNSLLLPVPRTEEPNSQYSVTDLKKIFSIEEESLAVTPVSPEWWKQAGLNLRVTETLEHLTTYFSDQDLPSDDT 396  little brown bat
Q5VXU9        395 KIEIFLPTKVLQLESCLEHKSHSSPIALIDEKSTNAHLSLPQKSPSLAk--EVPDLCFSDDYFSDKGAAKEEKPKNDQEP 472  human
A2ALV5        446 KLEIFLPTKVFQLESWLELKSRPLPIVPISEKSTDVHQLHPQKRPIPSsekEVPHLCLSGESISVKKSKVEANPKNDQEP 525  house mouse
XP_001490201  397 KMEIFLPTKLLHLESQLEYASCSSPIVLIKEKSANDHLSLPRKSASVA------DLCFSDEDISVKNLMREEIPKNDLEL 470 
2_pfamImport  389 TMEIFLPTKLLQLESSLEHKSCSSPIELIDEKSTNDHLLLSQNISSPAk--EVSDLCFSDDNLSVKQPTKEENPKNDLEP 466 
XP_005329767  397 KMEIFLPKKVLQLESWLDHKNCSSPTVLTNEKSINDNMLLPQKSPSLTk--EVPDLCWSDEYVSVERPKKEEKLKNDQEL 474  thirteen-line...
XP_023609036  397 KLEVFLPTKVPELESWLDHKSCSSPIVLMNEESTSDNLLLQQKSPSPA---EVPDLCFSDEYSSVHSPTKEEKPKDDQEL 473  little brown bat
Q5VXU9        473 VNRIIQKKENNdHFELDCT--GPSIKSPSSSIIKkASFEhgkKQENDLDLLSDFIMLRNKYKTCTSKTEVT----NSDEK 546  human
A2ALV5        526 EARIMQKPENS-CVGLGCSsqVPSAESASSSQIQ-ASYD---KKQDDLDLLSEFIILRSKHQTFPSEADVDvkshDHDQN 600  house mouse
XP_001490201  471 VHRIIQNEENNdCLELGCT--VPSIESSSPSKMEkASFKngeKQENDLDLLSDFIMLRNKYRTCTSSTEVT----DSDEK 544 
2_pfamImport  467 VYRISENKENEdYLELDCA--VPSDELSSSPKIEkASFKhgkKWENDLDLLSDFIMLRNKYKTCTSKTEVT----GNKEN 540 
XP_005329767  475 IDRTIQKKDNKdHVERDCM--VPSNESSSSSRIKiASFEpgkKQENDLDLLSNFIVLRNKYKTCTSKPEVI----DHDKK 548  thirteen-line...
XP_023609036  474 VSSIIQNNENKdCLELDCT--ELSTESASSSKIEkASFKcskRRENHLDLLSDFIMMRNKHKTCTSTTEVT----DSDEK 547  little brown bat
Q5VXU9        547 HD---KEACSLTLQEESPIVHINKTLEEINQERgTDSVIEIQASDSQCQAFCLLEAAASPILKNLVSLCTLPTANWKFAT 623  human
A2ALV5        601 NEfqdKEKYSLTLQEESLVASNSKAPEERCEER-TDGVIEIPASDTQCQAYCLLEATANPILKELVCLCTYPAANWKFAT 679  house mouse
XP_001490201  545 ND----EEHSLTLQEESPVVCTNKTLEKINQERrADNVIEIQASDSQCQAYCLLEAAATPIFKKLACLCTLPVANWEFAT 620 
2_pfamImport  541 DEfqdKEEPSLTLQEASPIVCTHKALEKMNQERrADNVIEIQASDSQCQAFCLLEAAATPIFKKLECLCTLPAADWTFAT 620 
XP_005329767  549 Dd---KEEYSSTLQEQSPVVSINKTPEKINEKReVDDVLEVQASDSQCQAYYFLEAAAAPILKKLVCLCAL-SANWKFAT 624  thirteen-line...
XP_023609036  548 Nd---KEEHSLTLQEESPIVYTNKTIEKINQEReADNVIEIQASDSQCHAYCLLEAAATPILKELGCLCTLPVASWKFAT 624  little brown bat
Q5VXU9        624 VIFDQTRFLLKEQEKVVSDAVRQGTIDEREMTFKHAALLHLLVTIRDVLLTCSLDTALGYLSKAKDIYNSILGPYLGDIW 703  human
A2ALV5        680 VNFDQTRFFLKEQEKKINDATHPDKNDDRKMTFRHAALLHLLITIRDVLLTCNLDTALGYLSNAKDIYKSVLDSRLDNIW 759  house mouse
XP_001490201  621 VVFDQTRFLLKEQQKVISDAIHQGTNDEREMTFKHAALLHLLVTIRDLLLTCSLDTALGYLSNAKDIYKSILGSYLDDIW 700 
2_pfamImport  621 VIFDQTRFFLKEQEKVISDAIQQGTNHEKEMTFKHAALLHLLVTIRDVLLTCGLDTALGYLSTAKDIYRNILGSYLDDIW 700 
XP_005329767  625 VIFDQTRFFLKEQEKILSDAIHQGTNDEREMTYKHAALLHLLVTIRDVLLTCSLDTALGYLSNAKDAYKSILGSYLDDIW 704  thirteen-line...
XP_023609036  625 VLFDQTRFLLKEQEKVVSDAIHQGTNAERETTFRHAGLLHLLVTIRDVLLTCSLDTALGYLSNAKDVYKSILGSYLDDIW 704  little brown bat
Q5VXU9        704 RQLEIVQFIRGKKPETNYKIQELQCQILSWMQSQQQIKVLIIIRMDSDGEKHFLIKILNKIEGLTLTVLHSNERKDFLES 783  human
A2ALV5        760 RQLKILQFIKEKRPKSNYKIQELQCQILSRLQNQQQMKVLIIIRMDSDGEKHLLIKTLKKIEGLTMTVLRSNDRKKILET 839  house mouse
XP_001490201  701 RQLAIVQFIREKNPETNYKIQELQCQILNWMQSEQQIQVLIIIRMDSDGEKHSLIKILDKMEGLTLTTLHSNRRKDFLES 780 
2_pfamImport  701 RQLEIIQFIREKNPETNYKIQELQCQILNWMQSEQQIKVLIIIRMDSDGEKHLLIKILNKMEGLTLTVIHSNKRKDVLES 780 
XP_005329767  705 RQLKIIQIIRGEKPEANYKIQELQCQIQSWMQN-QQIKVLIILRMDSDGEKHSLIKMLNKIEGLILTI------------ 771  thirteen-line...
XP_023609036  705 RQLEIVQFIREKMPETNYKIQELQCQILNRMQSEQQIKVLIIIRMDSDDEKRLLIEILNKMEGLTLTVLHSNKRKDFLES 784  little brown bat
Q5VXU9        784 EGVLRG-----------------TSSCVVVHNQYIGADFPWSNFSFVVEYNYVEDSCWTKHCKELNIPYMAFKVILPDTV 846  human
A2ALV5        840 TSILKG-----------------TNACVVVHNHSIGADFPWSSFSLVVEYNHVGHSCWAEHCQLLDIPFLAFKVAVPDTA 902  house mouse
XP_001490201  781 EAVLNG-----------------LSSCVVVHNQYIGADFPWSRFSFVVEYNYVENSCWTKHCEKLNIPYMAFKAILPDTV 843 
2_pfamImport  781 EGVLNG-----------------TSSCIIVHNQHIGADFPWTNFSFVVEYNFVENSCWTEHCKKLNIPHRAFKVILPDTV 843 
XP_005329767  772 -----ShsnkrrdfleskdvlngASSCVIVHNKNIGADFPWSNFSVVMEYNYVEHSCWSKHCKILNIPYMAFKVILPDTV 846  thirteen-line...
XP_023609036  785 EGVLNS-----------------TSSCVVIPNQYIGADFPWSNFSFVVEYNYVENSCWTKHCEQLNIPYMAFKVMLPDTV 847  little brown bat
Q5VXU9        847 LER--STLLDRFGGFLLEIQIPYVFFASEGLLNTPDILQLLESNYNISLVERGCSESLKLFGSSECYVVVTIDEHTAIIL 924  human
A2ALV5        903 LQR--DALLDGFGGFLLKIPIPYVFFASEGLLNTPEILRLLESNYNITLVERCCCGSLKLFGSTECYVVVTVDEHTAIVV 980  house mouse
XP_001490201  844 VKS--STLLDRFGGFLLEIQIPYVFFASEGLLNAPEILQVLESNYNITLVERCCSEALKLFGGTERYVVVTIDEHTAVIL 921 
2_pfamImport  844 LKR--STLLDSFGGFLLEIQVPYVFFASEGLLNTPEILQLLESKYNITLVERCCSESLKLFGGTECYVVVTIDEHTAVML 921 
XP_005329767  847 LKRsiLPDR--FGGFLLEIQIPYVFFASEGILNTPELLQLLESNYNITLMERPCSESLKLFGTKESYVVVTIDEQTAIIL 924  thirteen-line...
XP_023609036  848 LKR--NNLLDSFGGFLLEIQVPYVLFASEGLLNTPEILQLLESNYNITLVERCCSESMKFFGGTEYYVVVTVDEHTAIIL 925  little brown bat
Q5VXU9        925 QDLEELNYEKASDNIIMRLMALSLQYRYCWIILYTKETlNSEYLLTEKTLHHLALIYAALVSFGLNSEELDVKLIIAPGV 1004 human
A2ALV5        981 QDLEELHHEKASDNIIMRLMALSFQYSCCWIILYSKETlNSQYHLTEETLRHLAQVYAALVSSGLKSEELDVKLIIAPGV 1060 house mouse
XP_001490201  922 QDLEELNCEKASDNVITRLMALSFQYSYCWIILYTKETlNSEYHLTEKTLHHLALIYAALGSFGLKPEELDVKLIIAPGV 1001
2_pfamImport  922 Q------------------------------------------------------------------------LIIAPGV 929 
XP_005329767  925 QDLEELNYEKASDNIIMRLMALSFQYSYCWIILYTKEIlNSEYHLTEKTLHHLALIYAALVSSGLKSEELDVKLIIAPGV 1004 thirteen-line...
XP_023609036  926 QDLEELNCEKASDNIIMRLMALSFQYSYCWIILYAKKT-NSVYYLTEKTLHHLALIYAALVSFGLKSEELDVKLIIAPGV 1004 little brown bat
Q5VXU9       1005 EATALIIRQIADHSLMTSKRDPHEWLDKSWLKVSPSEEEMYLLDFPCINPLVAQLMLNKGPSLHWILLATLCQLQELLPE 1084 human
A2ALV5       1061 EETALIIRQIADHNLMTSTRDPHEWLDKSWVEVSPSKEEMSLLDFPCINPLVAQLMLHRAPSLHWLLIATPAELQELLPQ 1140 house mouse
XP_001490201 1002 EETALIIRQIADHNLMTSKRDPYEWLDKSWLEVSPSKEEMYLLDFPCINPLVAQLMLNKGPSLDWILLATLGQLQELLPE 1081
2_pfamImport  930 EEAALIIRQIADHNLMTSKRDPQEWLDKSWVEVSPSKEEMYLLDFPSINPLVAQLMLNKGPSLHWMLLATLGQLQELLPE 1009
XP_005329767 1005 EETALTIRQIADHNLMTSKKDPCEWLDKSWLEVSPSKEEMYLLDFPCINPLVAQLMLNKGPSLHWLLLATACQLQDLLPE 1084 thirteen-line...
XP_023609036 1005 EETALIIRQIADHNLMTSKRDPHEWLDKSWLEVSPSKEEMYLLDFPCINPLVAQLMLHKGPSLHWILLATLCQLQELLPE 1084 little brown bat
Q5VXU9       1085 VPEKVLKHFCSITSLFKIGSSSITKSPQISSPQENRNQISTLSSQ-------SSAsd-ldSVIQEHNEYyQYlglgetvq 1156 human
A2ALV5       1141 VPGKVLKHFCSITSLFKISSPSMTKSSQISSLQEDMNQTDLFISQ-------SSA-----PIIQEQEEYyPY-------- 1200 house mouse
XP_001490201 1082 VPEKVLKHFCGITSLFKINSSSVRKSPQISSLQENGNQTSTFTSQ-------TSAsgssgSVIQEHNKYdQYsdlgetah 1154
2_pfamImport 1010 VPEKVLKHFCSITSLFKISSSSITNSPQSPSPQENGNQTNTLTSQ-------SSAsgssnSVFQEHNEFyHYsdigetvy 1082
XP_005329767 1085 VPEKVLKHFCSITSLFKISSSSTTKSPQISSPLEESNQTSNFIPQssslvslD-------SVIQEYNEYyPYadlrervq 1157 thirteen-line...
XP_023609036 1085 VPEKVLKHFCDITSLFKISSSPITKSPQMSSPQENRNQTSTFPSQ-------SSAsdsfdSAIQEHEYY-QNlhlgetvq 1156 little brown bat
Q5VXU9       1157 EDKTTILndnSSIMELKE--ISSFLPPVTSYNQTSYWKDSSCKSNIGQNtPFLINIESRRPAYNSFLNHSDSESDVFSLG 1234 human
A2ALV5       1201 EDSEGTS---SSPVELRA--TPCMLPSAAPHSQRGCWEDPSCGPDPVQNnPSLMNAESKKVTWPSVPSWSDSESDVFSLA 1275 house mouse
XP_001490201 1155 DDTNTASndnSSLMALRD--MPCISPPVASYNQTSYWKDSSCNPNMVQNnPFLINRESRNVAGNSFLNQNGSESDVFSLG 1232
2_pfamImport 1083 EDTNSTSnskSSLMELRE--MPCVLPPMTSYSQASYWKDSSCNANIVHN-PFLINTESRTVTGNSFQNQNDSESDVFYLD 1159
XP_005329767 1158 EDTNTTSnynSSLMELRE--MPDTLPSVTSYNQTNYWKGSSCSPNIVQNnPCPDNIKSKKTALYSFPNQKDSKSDVFSLG 1235 thirteen-line...
XP_023609036 1157 EETNSTSnynFSLMELREreMPCVLPPVTSYSQTSYWKDSSYNPNVEKN-SFLINMESRNSAGNSFLNQNDSQTDVFSLD 1235 little brown bat
Q5VXU9       1235 LTQMNCETIKSPTDTQKRVSvvPRFINSQkrrthEAKGFINKDVSDPIFSLEGTQSPLHWNFKKNIWEQENHPFNLQYGA 1314 human
A2ALV5       1276 RTQVSCEPIMTLTDSQRRGT--NGFVNCP-----EAKGPRNMQVSTPVFLPENSQSHLHWDFKKNSCRKQIYSFNPSCGT 1348 house mouse
XP_001490201 1233 LTQMNGETIISPIDTQRRLT--SNFINYPkkgthEAKGRINKEVSAPLFSLEGSQSPLHWNFKENVWEQQNHSFNLQYGA 1310
2_pfamImport 1160 LTQMSCENITSPIDTQKRVA--PNFISYQekgthDAKGPIKKGAYASNFSLEGAQSPLPWNFKKNVWKQQNHSFNLEYGA 1237
XP_005329767 1236 LTQINCETTISPIDTQRRVapnfiny--qknrarEVKGTTYKEVSAPVLSLEGSQLSPRWNLQRNVYEKQNHSFNLKYGA 1313 thirteen-line...
XP_023609036 1236 LTQMNCESRISPINTQKRVA--LNFINYQkkgthEAKRPINKEEFAPVFSLEGSQSPPYWSFKENVWEQQNHSFNLQYGS 1313 little brown bat
Q5VXU9       1315 QQTACNKLYSQKGNLFTDQQKCLSDESEGLTCESSKD---ETFWRELPSVPSLDLFRASDSNANQKEFNSLYFYQRAGKS 1391 human
A2ALV5       1349 EQTTYNKWYSWKDDFSSNQPECLWDEMEDVTYRNANAgtrETFWRELPAVPSWDSPCASDSNANQRGFKGLDFCQRAGNY 1428 house mouse
XP_001490201 1311 ERTTCGKWCSQKDNLFTNQQRCLSDELDSFIRESSHTgtkNTFWRELPSVPSLDSFCASDSNVNPKEFNSLYFYQRAGKC 1390
2_pfamImport 1238 DQTTCDKWFSQKDNLFTNQQKYPSDELEGLIYESSNDetkKTFWKELPSVPSLDFFCAADPNVNQKEFSSLYFHQGAGKC 1317
XP_005329767 1314 EQTTHDKWYTHKDNLFTNQQKCLSDELEGFTCESSNVvtkKTLWRESTPVSSFDLLGASDSNVN-KEFNSLYFYQRAGKS 1392 thirteen-line...
XP_023609036 1314 EQTMCDKWYSQKDDLFTNQQKCLSDELEGLLYRSSSAgtkETFWKELPSVPSLDLFCASDSNINQKEFNSLYFYQRGRAC 1393 little brown bat
Q5VXU9       1392 LGQKRHHESSFNSGDKESLTGFMCSQLPQFKKRRLAYEKVPGRVDGQTRLRFF 1444 human
A2ALV5       1429 LGQRSLPVSSSNWGDYKTPTDLMYSQVPQPKKRRLMYEKVPGRVDGQTRLKFL 1481 house mouse
XP_001490201 1391 LGQKRHLESSSGSGDKKSLTDFMCSQLPQFKKRRLVYEKIPGRADGQTRLRFF 1443
2_pfamImport 1318 LGQKRHSESSSNSGDKKSLPDFMCSQLPQFKKRRLVYEKVPGRADGQTRLRFF 1370
XP_005329767 1393 LGQKRQLESSSYvEVKDTLAGLMCSQPSPLKKRRLMYEKVPGRIDGQTRLKFF 1445 thirteen-lined ground squirrel
XP_023609036 1394 LGQKRHAEPSSNSGDRKSLTDLPSSQLPQFKKRRLVYEKVPGRADGQTRLRFF 1446 little brown bat
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