Conserved Protein Domain Family
GlcD

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COG0277: GlcD 
FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion]
Statistics
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Structure
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COG0277 is classified as a model that may span more than one domain.
COG0277 is the only member of the superfamily cl43085
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_020445107    1 MaqredptgvdgadattadpstdpranydyrggeeHRPALVAaLRERI-DGEVRF--DEysrqLY--ATD----AS-AYE 70  
WP_054292539    1 Msgptrrgflagt-------------aalggtaliggeAAAT-EAEAVrESPVVPvgDA----RYedLVLrr-tNE-RFF 60  
WP_052427771    1 -------------------------------------MPPVN-SASRAeRPRTVTpdDG----RFltLTsg--mNQ-RYR 35  
WP_119728801    1 Mtetd----------------------------trpsGSPVA-STPSYg-GGVITadDP----RFd-SVLrg-yNQ-RFV 43  
YP_002346469  311 liecgrlnshiktrlgfkpkrlysivsqdlgipaatqtslsqlklasqldgEVRLasHP----AFdeWYltsvwNGrGPT 386 
WP_015100321    1 Msgttrrgfiagta-----------avggaalvgsptGAAVA-MEEGVrDSAVIAphDA----RYedLVLrr-tSE-RFF 62  
YP_002345389    1 --------------------------------------------------MKIIDknVS----TYetLQkg--fNL-RWP 23  
WP_080038648   32 srrwsivsqvtrrgfmggaaaaggtavlglgtpsntkpsvAK-EWGPVr----IGpgDP----RYadLAVrr-tNL-RFI 100 
WP_129186150    1 MtrtqltrrtvltaagastalfglsrlhgsagdllSAVVEAD-TSGAAaTALTVTptDR----QYwdLVsp--fNQ-RWV 72  
WP_119050561    1 Me--------------------------------------------------kITpgDT----RYadLAGkr-fNK-RFT 24  
WP_020445107   71 VT----PVGVVFPKSTDDVAAVMAYCAEEEIPVLPRGGGTSLAGQTV-----NEAVVLDFTKhMDDVlAVDPSeaglAG- 140 
WP_054292539   61 PR----PEYFRLPTSTEQVVRAVNDAVRAGKRITVRSGGHCYENFVGd----MAEVIIDMSA-MRQV-AFDER----RG- 125 
WP_052427771   36 AD----PEVVYLPESAEQVRVAVEESVTASKRLSVRSGGHCFEDFVDr---pEIEAVIDLSA-MNGV-YFDPG----HE- 101 
WP_119728801   44 AD----VDYVCVPASTQEVVDAVGRAVAEGKRVTVRSGGHGFEGSASt----DGGVLIDLSE-MNEV-SFDHE----RR- 108 
YP_002346469  387 RR----PAGIVRAATEADVIRTIVFAKERGMEVSVRGSGHNYVGCFLr----VDTLMLDISG-LKGL-DIDSR----HK- 451 
WP_015100321   63 PR----PACFRLPTTTEQVVRAVDEAVRQGKRVTVRSGGHCYENFVGd----GAEVIIDMSA-MRQV-TFDRR----RA- 127 
YP_002345389   24 PNveqgAETIYICTTPDEVFAATNTALAAGNRITVRSGGHCYEGFVSnklstERLSIIDLGE-MSGL-DYDED----KTi 97  
WP_080038648  101 PR----PEYFHVVGSAEQVERAVEEAVKAGKRVTVRSGGHCYENFVGd----GAQVVIDMCE-MSEV-YFDDR----RG- 165 
WP_129186150   73 GS----PDAVRLPTTTEQVVNAVREAVRAGKRLSVRGGGHGYEDWIYn---sQIKVVVDMSL-MRRV-YFDPA----RQ- 138 
WP_119050561   25 GK----PEYILLPTSTQEVVEAVQEAVTNKRRPVVRSGGHCLEGFVSd---pGAQVLIDVSL-MTGL-YYDAE----RG- 90  
WP_020445107  141 -----------TARAQPGVTLGELNAAC-ENHDLKFAPDPawgDKSALGGAIGNNSTGAHSLQY-GKTDAYVESVEAVLA 207 
WP_054292539  126 -----------AFVIEPGASLWEVYQRLyLGWGVTIPGGQc--GGVAAGGHIQGGGYGPLSRQL-GSVVDYLYAVEIVVV 191 
WP_052427771  102 -----------AFAVEAGARLLDVYERLyLDWGVTLPGGLc--YSVGAGGHVAGGGYGLLSRQH-GLTVDHLYGVEVVVV 167 
WP_119728801  109 -----------AFALQPGATIGDVYRRLyKGWGVTLPAGEg--TEVGIGGHLAGGGFGPLTRRL-GAIVDYLCAVEVVVV 174 
YP_002346469  452 -----------RAIVESGVSSGQLCHAL-AAKGLAFPTGHv--KEVGISGFLLGGGLGINCSQWgGMSVFNVQALDIVTA 517 
WP_015100321  128 -----------AFMIEPGASLWSVFERLyLGWGVTIPGGQc--GGVAAGGHIQGGGYGSLSRQF-GSVVDHLYAVEVVVV 193 
YP_002345389   98 tslwdankntyRFKSLTGNQNWNGYVSLyKRSGRTIPGGSc--YSVGVGGHISGGGYGLLSRLH-GLTVDWVTGVDILVP 174 
WP_080038648  166 -----------AFAIEAGATLMQVYRTLyLGWGVTIPGGQc--GSVAAGGHIMGGGYGQHSRRL-GSVVDYLHAVEVVVV 231 
WP_129186150  139 -----------AFAVEAGASLLDVYTGLyEGYGVTVPAGVc--ATVGIGGHACGGGYGMLSRKH-GLIVDYLEAVEVVTV 204 
WP_119050561   91 -----------AFAVEAGVTVGEMYRRLfLGWGVVLPAGEh--PGIGMGGHVLGGAFGFLCREY-GLAADYLYGVELVTV 156 
WP_020445107  208 ----DGTMTTLGevdletireeadpapdsgdllpriyeavrravdeyadeideayPDmkrnvSGYnldrlvaearggigp 283 
WP_054292539  192 d--rGGRARAVV-------------------------------------------AT-----REPgdp------------ 209 
WP_052427771  168 d--aDGRARVVT-------------------------------------------AT-----REPtdp------------ 185 
WP_119728801  175 d--aAGRARAIV-------------------------------------------AT-----DDPgdp------------ 192 
YP_002346469  518 ----DGHLRHVS-------------------------------------------ET-----QEP--------------- 530 
WP_015100321  194 d--rSGRARAVV-------------------------------------------AT-----REPgdd------------ 211 
YP_002345389  175 vgnaHRLAFRHV-------------------------------------------RA-----DSVsev------------ 194 
WP_080038648  232 d--rSGRARTVV-------------------------------------------AT-----RDPsdp------------ 249 
WP_129186150  205 s--aTGIVRPVV-------------------------------------------AT-----RDPadp------------ 222 
WP_119050561  157 d--aSGKAHSVI-------------------------------------------AT-----REAtdp------------ 174 
WP_020445107  284 tgedfgesgtvNLARLLAG-SEGTLGIVTEATVSL-----------EPI-PETKAVALLAYED--L--VTA-MEDVEPI- 344 
WP_054292539  210 ---------nrDLWWAHTGaGGGSFGIVTRYWMRTpgatgsdpaqlLPKpPAATLSAGVGWDWrdVtkESF-FALLRNYg 279 
WP_052427771  186 ---------nrELWWAHTGgGGGNFGIVTRYLFRSvgatg-dprrlLPTpPDEVLLSAVSLPWreLgrEGL-TALLGNFt 254 
WP_119728801  193 ---------hhDLWWAHTGgGGGNFGVVTRYWVRTpgvtstdprelLPRaPIRWRNGIVAWSWdtMteDAF-VRLLRDFg 262 
YP_002346469  531 -----------DLFWAARGaGPCSFFVVTRFYLSC-----------YSL-PRVITNSLYTLPF-----TYLhDLLARLEd 582 
WP_015100321  212 ---------nrDLWWAHTGgGGGNFGVVTRYWLRSpgangndpsrlLPKpPATTLGATLWWSWrdVteESF-HRLLRNYg 281 
YP_002345389  195 ---------drELLMACCGaGGGNFGIIIAYYFDD-----------LPKaPQKAYWIPLTYPWssLk-ATF-PAFLKAYw 252 
WP_080038648  250 ---------nhDLWWAHTGgGGGNFGVVTRYWMRDpkakgkdprtlLPKpPPALLVCAPAWSWgdMtrESF-TALLRNHg 319 
WP_129186150  223 ---------nhDLWWAHTGgGGGTFGVVTRYWFRSknttstdptelLPApPVQVLSVTAEWPWdqIteQGF-AKLLRAYg 292 
WP_119050561  175 ---------nrELWWAHTGgGGGNFGIVTRYWLRSpdvtgtdpyiaLPKaPASITTFRIAWDWkdVdeTSF-SRLMQNFg 244 
WP_020445107  345 --LEHDPAAVEVLDDv--------lLNLArDTe--EfgalvntvVPEGAG-AM-LLVEFYAeDD--ARGR-----EQTAD 403 
WP_054292539  280 ewHERNSAPGSRYasl------fspLLIT-RRmkgDe----------pGGfGMvVSM-----DAtvPDAEgl-lrAYIAD 336 
WP_052427771  255 awHAEHSEPRTREtal------agmLMLN-HAsngHv--------------GMlTQV-----DAgvDGAAdl-lrNYLDR 307 
WP_119728801  263 gwFERNSEPGCAGanl------tgyFAAT-HRs---------------GGmIVvGSMI----DDgiPGAErm-mnGFFDE 315 
YP_002346469  583 asPP-----TNLQ------------VMVS-VSpptSg-------DTPA---VLlNILAFTD-SP--QEAQal--cESFET 629 
WP_015100321  282 ewHERNSAPDSRYasl------fspLLIT-RRntgAd----------pGGfAMvPAL-----DGslPDADrl-lrDYLAE 338 
YP_002345389  253 qwFADNDVNATSTKEgvgngglftlLKLN-HIdasDn---------------VvLAIQYTGpNGqvGGANdiplnDFIEK 316 
WP_080038648  320 ewHERNSAPGTPYagl------wsaLIVQ-SRtpgAd----------pGGmILpTMM-----DAsvPDAGrl-ltEYFAA 376 
WP_129186150  293 twHERHSGRADPYagl------cswLFVP-HRtggKi--------------NVlIQM-----DGsrGDAEhl-vrAFLDE 345 
WP_119050561  245 iwALQHSGPDSPYtpl------fsiLFLN-HRnigR----------------LeMKG-----LAtgANAArl-ieEHLAA 295 
WP_020445107  404 LLADRvpadvretefsppgnvstdaalRAF----------------------------A-GF-E---AH-----DQAE-- 443 
WP_054292539  337 VTK------------------------GVAgtk-----------------------eiLpLTrRp-wLAavklgSLSQtd 368 
WP_052427771  308 VLDGT----------------------GVTprpmndaag-----------efgpmpelAePRrLp-wLRatrmiGTNTpf 353 
WP_119728801  316 VSR------------------------NVGiep-----------------------vtRsTDdVvswLYfftfpNRGEpg 348 
YP_002346469  630 RLELP----------------------LTal---------------------------aiNQpSn-fETiyeqfSSMVvs 659 
WP_015100321  339 VTE------------------------GVPgti-----------------------tvTpPHrLp-wLAavkagSLSQsd 370 
YP_002345389  317 MNAAA----------------------GMTptiyddfilpnippfkhlypgrkigrtvDeSAsMd-wLHvtqmiNGSGs- 372 
WP_080038648  377 LTR------------------------GVTaka-----------------------viPeAQrLp-wYHaisteALSSgq 408 
WP_129186150  346 LDAAA----------------------GVLr--------------------------tEnVLrTe-wLKatrhmGMGSpl 376 
WP_119050561  296 IAGPI----------------------GLPytk-----------------------qiEeSSwLr-fALnpfpeLFQPgf 329 
WP_020445107  444 -----RD-RFWKlrKSGLPiL-LS-RTtdakhisFIEDCA----VPP--E-H--LaEYvERFeailedhD-T-F----AS 500 
WP_054292539  369 ---esGMyKGKA--AYLRKrFtDAqIA-------TAYEYLtstdHDN--EsAl-L-WL-LSYg------GkVnTvspdAT 425 
WP_052427771  354 ltdptLRaEHKS--AYGRHrVpASrAS-------VLYDHLtartPNN--PnSm-L-VV-MSYg------GaInGvgtsET 413 
WP_119728801  349 d-iatRRfKLKS--AYLRRaYtERqIA-------TAYRHLd---TDG--EkSlnL-IL-IGYg------GqVnAvapdAT 405 
YP_002346469  660 -------kRFYA--DNILTdNtQElVS-------ILSRYLs--dAPS--RgAl-T-TI---Fw------RgVtTy--pQA 706 
WP_015100321  371 ---esGMfKAKA--AYLRRrFtDEqIR-------TAYTHLtstdHDN--ErAl-L-LL-VSYg------GkVnTvapdAT 427 
YP_002345389  373 ----nQRgKYKS--DYQIKqFsDEmCH-------ALLTHLttatADKrfNqSl-V-QI-DSYg------GaInSrgigAT 430 
WP_080038648  409 ---esGRfKAKS--AQLRRrFtDRqIG-------LAYDRLsvpaPAG--SnGv-L-LL-ASYg------GqVnTvapgAT 465 
WP_129186150  377 qtsptLRgEHKS--AYLRRsFtEEhIA-------AAWKHLtradYDN--GyGm-F-VA-TSYg------GaInDvapdAT 436 
WP_119050561  330 ---dnVQaKVKD--AFFRRpFiDSqVA-------TAYKYLtadaPIG--Gg---L-GM-ATYg------GkVnTvtpdAT 384 
WP_020445107  501 FYAHAgPGVLHVRPLv---NTKTLdgvEQMVGIADAVTDVVT-ELGG---------SVSGEh-GdgrARSQ--------- 557 
WP_054292539  426 VLPQR-DSIMKVIYTvswtDPKAE---NANLDWIRRWYSAMYkETGGvpvpngvndGSYINypDs--DTLDpkwntsgva 499 
WP_052427771  414 ASVQR-DSHYKLLYQafwqHEAED---EDNIAWVRSLYEHTYaDSGGvpvpdefsdGCYVNypDa--DLHDerhnrsgkr 487 
WP_119728801  406 AIAQR-DSILKAAYLsawsDERED---DARIADLRALYHDVYaETGGvpvpneyndGAYINypDr--DLADpewntsgvp 479 
YP_002346469  707 AF-SA-HGKFFVSTYaqwdDAKDD---SVNKYWLKRMYDELQeIARS----------RYINeyDl-eTRAG--------- 761 
WP_015100321  428 ALSQR-DSIMKVIYTvtwtDPNRE---QANLDWIRRWYSAMYrDTGGvpvpnsvndGSYINypDv--DTTDpkwnksgip 501 
YP_002345389  431 AVSQR-NSLLKAQYQtywtNEADD---QTHLTWIRNIYAAVH---NGkpap-pefeGCYINypDi--DMKYtdsgeedpn 500 
WP_080038648  466 AVAER-DSILKALFLggwtEGDGA---ES-IAWVRRLYREMYaDTGGvpvpngangGAYINypDi--DLADpawntsgvp 538 
WP_129186150  437 AVHQR-DAILKLLFQtywtDPSQD---ARHVSWLRDLYEEMYaSTGGvpvpgevtaGCYVNypDg--DISDparnqsgvp 510 
WP_119050561  385 ASPQR-DSILDVACNtgwiDPNGA---GPSLDWVRNFYKDLFpGSGGvpvpneqtdGCMINhpDt--DLADpawnqsgvp 458 
WP_020445107  558 WNKKLYGVEIWD---LSRDLKAAFDPDWLLNPGQ-IC----G 591 
WP_054292539  500 WHALYYK-DNYR---RLQQVKARWDPRDVFHHVMsVk----L 533 
WP_052427771  488 WHDLYYK-DNYP---RLQRAKARWDPSDVFRHPQsVr----L 521 
WP_119728801  480 WSTLYYK-HNYP---RLQQVKKRYDPRNEFRHALsIe----L 513 
YP_002346469  762 ETSKCFAAENWE---RLQRLRLEYDPDGVFVDVQqLEehgdQ 800 
WP_015100321  502 WHTLYYK-DNYR---RLQQVKQRWDPRDVFHHAMsIt----L 535 
YP_002345389  501 WLNLYYG-WDTQlikRLIALKARIDPNNIFHHELsIp----L 537 
WP_080038648  539 WSTLYYG-GNYP---RLQRVKARWDPRGVFRHALsVr----A 572 
WP_129186150  511 WTTLYWG-DNYS---RLQRVKAAYDPTDFFRHAQsVr----L 544 
WP_119050561  459 WHTLYYK-ENYP---RLQQVKAHWDPLNIFHHALsIq----A 492 
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