2RPR


Conserved Protein Domain Family
FLYWCH

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pfam04500: FLYWCH 
FLYWCH zinc finger domain
Mutations in the mod(mdg4) gene have effects on variegation (PEV), the properties of insulator sequences, correct path-finding of growing nerve cells, meiotic pairing of chromosomes, and apoptosis. The occurrence of FLYWCH motifs in mod(mdg4) gene product and other proteins is discussed in.
Statistics
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PSSM-Id: 461332
Aligned: 41 rows
Threshold Bit Score: 55.042
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2RPR_A         13 FLRTSLGGRFLVHESFLYRKEKAA----GEKVYWMCRDQAR--LGCRSRAITQ-----GHRIMVMRS-HCH 71   human
Q86B87        452 YASTTKGGVKLIFNGHLFKFSFRK----ADYSVFQCCYREHg-EECKVRVVCD-----QKRVFPYEGeHVH 512  fruit fly
Q6IDX0        458 YLTNRFGSAKVVLDEHQYVYHFAA----KGVSYYRCDQFKR--NQCPAQVLVVs---gMTHAVNVE--HTH 517  African malaria mosquito
Q6NP69        365 FLPSAKGRKVLCLSQHLFHFDSQSr--sNGHMFFTCINRRDkaNTCHVRITLDpv-enGPVVLRINGeHTH 432  fruit fly
Q6NP69        596 TLRSAKGHELLCVDGYIYHAKNRGv---ISRNYWVCIKSRDpdINCKSRISTAtqkdgSIRVLRVYNsHSH 663  fruit fly
Q6NP69        162 MLRRRDGRVMVCIDGHLYYLAGKSy--kGDIFRWTCVRKRD--IECTARICTEatlagAHRLHAVDT-DAH 227  fruit fly
Q9XWQ6        134 PYTPRGIRERVLFDEHLYVFDKCSy--dSKKRFFRCERKNT----CPARIHTPf---dAERVIHKVQvHNH 195  Caenorhabditis elegans
XP_002632857  145 PHRSRMTRDRVFYESHVYIFDKSSy--dNKKKFYRCEKKNT----CPARLHIPs---dSYRVIFMTQeHNH 206 
Q18225        143 EYKPRNVREKVYADGYIMSFDKKSc--cGTKEFWRCERKND----CNARMHSDi---nTREIVRKLHpHNH 204  Caenorhabditis elegans
Q17IM0        257 YYSTKGDRPSIVVNGYRFHKEKALsvtfPSQIYWRCSAK-----NCLGMIVTTa---dLHRFRMHKN-HNH 318  yellow fever mosquito
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