3ZS9,6SO5,3UG6,3ZQ6


Conserved Protein Domain Family
ArsA_ATPase

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pfam02374: ArsA_ATPase 
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Anion-transporting ATPase
This Pfam family represents a conserved domain, which is sometimes repeated, in an anion-transporting ATPase. The ATPase is involved in the removal of arsenate, antimonite, and arsenate from the cell.
Statistics
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Structure
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PubMed ReferencesClick to see Conserved Features Help

pfam02374 is a member of the superfamily cl38936.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3ZS9_A  18 HKWIFVGGKGGVGKTTSSCSIAIQmaLSQPNKQFLLISTDPAHNLSDAFGE------KFGKDARKVTgmNNLSCMEIDPS 91  baker's yeast
O52027  19 TEFVFFSGKGGVGKSTVSCATATW--LADNDYDTLLVTTDPAPNLSDIFNQ------DIGHEVTAIDdvPNLSAIEIDPD 90  Halobacterium salinar...
O66674   1 MRVFFFGGKGGVGKTTASSAFAVK--LSEQGKKVLLLSTDPAHSLSDVFNT-------ELQGETKLS--ENLTVKEIDLN 69  Aquifex aeolicus VF5
O66908   1 MRIILFSGKGGVGKTTISAATGYK--LSQLGKKVIVVSLDPAHSLADSFDVpeeerrKAKGLPIKIN--ENLEIQEIDIQ 76  Aquifex aeolicus VF5
Q55794   1 MRVILMTGKGGVGKTSVAAATGLR--CAELGHKTLVLSTDPAHSLADSFDL------ELGHEPRLVK--ENLWGAELDAL 70  Synechocystis sp. PCC...
Q46366   1 MRILTFTGKGGVGKTSVSAATAVR--LSEMGHRTLVLSTDPAHSLSDSFNI------QLGAEPTKIK--ENLHAIEVNPY 70  Chlorobaculum tepidum...
P30632  18 LKWIFVGGKGGVGKTTCSCSLAAQ--LSKVRERVLLISTDPAHNISDAFSQ------KFTKTPTLVEgfKNLFAMEIDSN 89  Caenorhabditis elegans
6SO5_B  39 LKWIFVGGKGGVGKTTCSCSLAVQ--LSKGRESVLIISTDPAHNISDAFDQ------KFSKVPTKVKgyDNLFAMEIDPS 110 human
3UG6_B  26 TKYIMFGGKGGVGKTTMSAATGVY--LAEKGLKVVIVSTDPAHSLRDIFEQ------EFGHEPTKVKgyDNLYVVEIDPQ 97  Methanocaldococcus ja...
3ZQ6_C  14 TTFVFIGGKGGVGKTTISAATALW--MARSGKKTLVISTDPAHSLSDSLER------EIGHTPTKIT--ENLYAVEIDPE 83  Methanothermobacter t...
3ZS9_A  92 aalkdmndMAVSRANNNGSDGQGDDL---GsLLQGGALADLTGSiPGIDEALSFMEVMKHIKrqeqgeGETFDTVIFDTA 168 baker's yeast
O52027  91 --------VAAEEYRQETIEPMRALL---G-DEEIQTVEEQLNS-PCVEEIAAFDNFVDFMD------SPEYDVVVFDTA 151 Halobacterium salinar...
O66674  70 --------EELKEYRSRVFKLAEATLrkeTlRELEGIIHSLEES-PGIEDVVIFEALSKEVVy----rENEYDYIVVDTA 136 Aquifex aeolicus VF5
O66908  77 --------EEIERYWGEVYRFIELLF---HtTGLHEILADELAIlPGMEEITSLLYVNKYYR------EGNHDVLILDLP 139 Aquifex aeolicus VF5
Q55794  71 --------MELEGNWGAVKRYITQVL---QaRGLDGVQAEELAIlPGMDEIFGLVRMKRHYD------EADYDVLIIDSA 133 Synechocystis sp. PCC...
Q46366  71 --------VDLKQNWHSVQKYYTRIF---MaQGVSGVMADEMTIlPGMEELFSLLRIKRYKS------AGLYDALVLDTA 133 Chlorobaculum tepidum...
P30632  90 pngegvemGNIEEMLQNAAQNEGGSG---GfSMGKDFLQSFAGGlPGIDEAMSFGEMIKLID------SLDFDVVVFDTA 160 Caenorhabditis elegans
6SO5_B 111 l-------G-VAELPDEFFEEDN------MlSMGKKMMQEAMSAfPGIDEAMSYAEVMRLVK------GMNFSVVVFDTA 170 human
3UG6_B  98 k------aMEEYKEKLKAQIEENPFL---G-EMLEDQLEMAALS-PGTDESAAFDVFLKYMD------SNEFDVVIFDTA 160 Methanocaldococcus ja...
3ZQ6_C  84 v------aMEEYQAKLQEQAAMNPGM---GlDMLQDQMDMASMS-PGIDEAAAFDQFLRYMT------TDEYDIVIFDTA 147 Methanothermobacter t...
3ZS9_A 169 PTGHTLRFLQLPNTLSKLLEkfgeiTNklgpml-----nsfmgaGNVDISg----KLNELKANVETIR---QQFTDPDLT 236 baker's yeast
O52027 152 PTGHTIRLMELPSDWNAELE-----KG-----------------GSTCIG-----PAASMDDKKADYEraiDTLSDESRT 204 Halobacterium salinar...
O66674 137 PTGHTLGLLKTVRNLGNFLEeivklKEkvyel--------kklsGKSVHEe----ALEYLKERKERFKkfsEIIYDKSY- 203 Aquifex aeolicus VF5
O66908 140 PTGESIRFVSMPTVMKWYMKkifktERlimkvar----ptvgrmTDVPLPde--eYFKALETFYERLKgvdEILINPDIT 213 Aquifex aeolicus VF5
Q55794 134 PTGTALRLLSLPEVGGWYMRrfykpLQgmsvalrplveplfrpiAGFSLPdk--eVMDAPYEFYEQIEaleKVLTDNTQT 211 Synechocystis sp. PCC...
Q46366 134 PTGETLRLLSLPDTLSWGMKav-knVNkyivrplskplskmsdkIAYYIPpe--dAIESVDQVFDELEdirEILTDNVKS 210 Chlorobaculum tepidum...
P30632 161 PTGHTLRLLQFPTLLEKVFTkilslQGmfgpmmnq--fggmfgmGGGSMNe----MIEKMTTTLESVKkmnAQFKDPNCT 234 Caenorhabditis elegans
6SO5_B 171 PTGHTLRLLNFPTIVERGLGrlmqiKNqispfisq--mcnmlglGDMNADq----LASKLEETLPVIRsvsEQFKDPEQT 244 human
3UG6_B 161 PTGHTLRFLGMPEVMDKYMTkliklRKqmsgfmkm--mkkllpfGGKDEDidydkMLEELEKMKERIVrarNILSDPERT 238 Methanocaldococcus ja...
3ZQ6_C 148 PTGHTLRLLSFPEIMDSWVGkmikiRRqigsmaka--fknilpfMGDEEee--drALQDMEATKKQINaarEVMSDPERT 223 Methanothermobacter t...
3ZS9_A 237 TFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQlLFAENDQEh--NcKRCQARWKMQKKYLDQIDELYEDFHVVKM 314 baker's yeast
O52027 205 SFAFVGKPESSSIDEIERSASDLAELGISSQLLVVNG-YLPESVCE---D-PFFEGKRADEQAVIDRVESTFDQQALATY 279 Halobacterium salinar...
O66674 204 -FFAVLTPEKLPFEETKRLVNSLKHYGIRVKALIINK-VLPENPQD-----EFLKARKEVEKKFLKEIENYFMDIEKISI 276 Aquifex aeolicus VF5
O66908 214 SIRIVSNPEKMVLKESQRAFLYFLLFGVNVDAVIVNK-VIPEEVIQq-eNcSFLEKWLNIQKKYVKEIESYFSPVPVFKV 291 Aquifex aeolicus VF5
Q55794 212 SVRLVTNPEKMVLKESLRAHAYLSLYNVSTDLVIANR-ILPETIDD-----PFFQRWKSNQQVYKQEIYDNFHPLPVKEA 285 Synechocystis sp. PCC...
Q46366 211 TVRLVMNAEKMSIKETMRALTYLNLYGFKVDMVLVNK-LLDAQENS-----GYLEKWKGIQQKYLGEIEEGFSPLPVKKL 284 Chlorobaculum tepidum...
P30632 235 TFVCVCIAEFLSLYETERLIQELSKQGIDTHNIIVNQlLFPDTDANgtvScRKCASRQAIQSKYLTDIDELYEDFHVVKL 314 Caenorhabditis elegans
6SO5_B 245 TFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQlVFPDPEK----PcKMCEARHKIQAKYLDQMEDLYEDFHIVKL 320 human
3UG6_B 239 AFRLVVIPEEMSILESERAMKALQKYGIPIDAVIVNQ-LIPEDVQc-----DFCRARRELQLKRLEMIKEKFGDKVIAYV 312 Methanocaldococcus ja...
3ZQ6_C 224 SFKMVVIPEEMSIYESERAMKALEKYSIHADGVIVNQ-VLPEESDc-----EFCNARRKLQQERLKQIREKFSDKVVAEV 297 Methanothermobacter t...
3ZS9_A 315 PLCAGEIRGLNNLTKFSQFLNK 336 baker's yeast
O52027 280 PLQPGEIAGLELLSDVGGVLYD 301 Halobacterium salinarum NRC-1
O66674 277 PYQKEEVVGYEKLKEFSKFLPL 298 Aquifex aeolicus VF5
O66908 292 PLLEEEVVGLERLEKLAQLIYG 313 Aquifex aeolicus VF5
Q55794 286 PLFSEEMCGLAALERLKDTLYK 307 Synechocystis sp. PCC 6803 substr. Kazusa
Q46366 285 KMYDQEIVGVKSLEVFAHDIYg 306 Chlorobaculum tepidum TLS
P30632 315 PLLEAEVRGGPAILQFSERMVD 336 Caenorhabditis elegans
6SO5_B 321 PLLPHEVRGADKVNTFSALLLE 342 human
3UG6_B 313 PLLRTEAKGIETLKQIAKILYG 334 Methanocaldococcus jannaschii DSM 2661
3ZQ6_C 298 PLLKKEAKGIETLEKIAEQLYG 319 Methanothermobacter thermautotrophicus
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