2A78,2ERY,1X1R,3BRW,1CLU,2FN4,1XTQ,3RAP


Conserved Protein Domain Family
small_GTPase
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smart00010: small_GTPase 
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Small GTPase of the Ras superfamily; ill-defined subfamily
SMART predicts Ras-like small GTPases of the ARF, RAB, RAN, RAS, and SAR subfamilies. Others that could not be classified in this way are predicted to be members of the small GTPase superfamily without predictions of the subfamily.
Links
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Statistics
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PSSM-Id: 197466
Aligned: 39 rows
Threshold Bit Score: 233.991
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2A78_A        17 ALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCV 96  human
NP_005605      5 KSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILV 84  human
XP_340810     23 NCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILV 102 Norway rat
CAA26131       2 REYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVKVNERQCMLEIVNTAGTEQFTAMRNLYMKNGSDSCWS 81  fruit fly
AAA21445       4 KDYKIVVLGSGAVGKSSITVRFVQGIFLVKYDPTIEDSYRKQLDLDGQQYVLEILDTAGTEQFTAMRDLYMKTGQGFVLV 83  Entamoeba histo...
NP_499079     12 LNRKVAVMGYPHVGKSALVLRFTQNIFPERYESTIEDQHSKHIAAFHRDYHLRVTDTAGQQEYTVFPRSCSLDINGFILV 91  nematode
NP_476857      2 REYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLV 81  fruit fly
XP_001233104 222 REYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDASPSVLEILDTAGTEQFASMRDLYIKNGQGFILV 301 chicken
3BRW_D         2 REYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALV 81  human
1XTQ_A         5 KSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILV 84  human

2A78_A        97 FSITEMESFAATADFREQILRVKED--------ENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQW-N--VNYVETSAKTR 165 human
NP_005605     85 YSVTSIKSFEVIKVIHGKLLDMVGK--------VQIPIMLVGNKKDLHMERVISYEEGKALAESW-N--AAFLESSAKEN 153 human
XP_340810    103 FSLDNRDSFEEVQRLKQQILDTKSClknktkenVDVPLVICGNKGDRDFYREVEQREIEQLVGDD-PqrCAYFEISAKKN 181 Norway rat
CAA26131      82 TRSRRNRRLTICRTREQILRVKDTD---------DVPMVLVGNKCDLEEERVVGKELGKNLATQF-N--CAFMETSAKAK 149 fruit fly
AAA21445      84 YSIMAQSTYNDLDPIHDQIVRVRDT--------ENVPIIVVGNKCDLESQRIVSQDDGKALADKY-G--AEFLEVSAKAE 152 Entamoeba histo...
NP_499079     92 YAIDDRKSFEMCSNIYEKIVRTYGD--------TSIPIVIVGNKTDLSTQRVVRAEEGEELARQW-D--AKFVEITARES 160 nematode
NP_476857     82 YSITAQSTFNDLQDLREQILRVKDT--------DDVPMVLVGNKCDLEEERVVGKELGKNLATQF-N--CAFMETSAKAK 150 fruit fly
XP_001233104 302 YSLVNQQSFQDIRPMRDQIIRVKRY--------EKVPVILVGNKVDLESEREVSSNEGRALAEEW-G--CPFMETSAKSK 370 chicken
3BRW_D        82 YSITAQSTFNDLQDLREQILRVKDT--------DDVPMILVGNKCDLEDERVVGKEQGQNLARQWnN--CAFLESSAKSK 151 human
1XTQ_A        85 YSVTSIKSFEVIKVIHGKLLDMVGK--------VQIPIMLVGNKKDLHMERVISYEEGKALAESW-N--AAFLESSAKEN 153 human

2A78_A       166 ANVDKVFFDLMREIRAR 182 human
NP_005605    154 QTAVDVFRRIILEAEKM 170 human
XP_340810    182 SSLDQMFRALFAMAKLP 198 Norway rat
CAA26131     150 VNVNDIFYDWsgrstrs 166 fruit fly
AAA21445     153 IRISDIFTTLIKRINAM 169 Entamoeba histolytica
NP_499079    161 NRVHEVFELLLREIEIS 177 nematode
NP_476857    151 VNVNDIFYDLVRQINkk 167 fruit fly
XP_001233104 371 TMVDELFAEIVRQMNya 387 chicken
3BRW_D       152 INVNEIFYDLVRQINR- 167 human
1XTQ_A       154 QTAVDVFRRIILEAEKl 170 human
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