Conserved Protein Domain Family
7TM_GPCR_Str

?
pfam10326: 7TM_GPCR_Str 
Serpentine type 7TM GPCR chemoreceptor Str
Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.
Statistics
?
PSSM-Id: 402099
Aligned: 160 rows
Threshold Bit Score: 243.132
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_002635229   8 KVFVQWTSFLCSLVFNSILIFLIITKSPKKMGNYRWLMIYFSCFAIFFSTLDMIVGPFIHAHGTSACLL-MRRSEPED-V 85 
4_pfamImport   1 ADVISYSAYFVTLALNSTLIYLTKYCSTRLTIIYRRMIIGFAVFGIGFSTLDIVVRPIMHSYNGCFLYF-SLKGSFRS-S 78 
6_pfamImport   1 AQRVAQFGFFATTTSCTVLILLTIYGVKRDFGSYKNLLLMFAGLGIVFATTEVLLFPNLHSYNAGYFFY-SMERPFRL-D 78 
O17716        21 AQLVAQIGFFTTTVFCGILIFLTVFGGQKNFGSYKNLLVLFSTVGIFFSVVELTLYPNVHSFYAGYFFYsT-QRPFGL-K 98  Caenorhabditis ...
XP_002637697  18 AQSVAEAGFCSTMVFCGILIFLTIFGVKRNFGSYKYLLILFPAVGIFFATVELILYPNVHSFNAGYFFYsT-RRPFGV-G 95 
O62017        12 THFIPKLGFVTTFMSGLCLLFLNYFGAQKNFGSYKYLISAFTMLGMIFATVEIIVYPNVHNYKASFLFYsF-EESFGLsG 90  Caenorhabditis ...
O17896        13 CIFMGDLGFFSNAFFGFILVYLTLFYIKRQFGSYKYLLVNFQLLGFIFASFEFLFHTFLHTYNASLIYFsL-SRPLGL-S 90  Caenorhabditis ...
O45809        10 TKLISKVGFLSTTILGMLFVCLTVCFVKRDFGSYRNLLIVFSFLGFLFSASEYMIHPMIHSYNSGFVFFtE-PHLSLV-S 87  Caenorhabditis ...
XP_002637694  10 TRFIAKVGFIFTSLLVLLFIFLTIYFVKRDFGSYRNLLIAFSILGFSFSSSEYIVHPMIHSYSAGFVFFtN-PQTSIV-S 87 
P91984        10 SLLASEIGFFSTLIVNSFLVHLIIFYTKQVFGAYKYLVLSFSLMGIVFATAEFIVKPMTHNYKASFTFFtL-ERPFKC-S 87  Caenorhabditis ...
XP_002635229  86 ANVQYVLLmklnqyftVLLCSCFGVTITFFAIHFVFRYFALERRGRIAYFDGKYFLIWLAIPVVCGTVWGLALHFFVGHT 165
4_pfamImport  79 KAITEMLL--------AIYSAVYAAILSFLTIQYIYRVCVLRCPQLVQYFRGWRFILWLGYVFMFGLAWGVITYFYAYPD 150
6_pfamImport  79 TKNVSRFL--------VIYTGLYGSTICLLSVQFVYRYWAVFSESKLKFFKGWRFIFCIMYCAAFGADWGLSIYYFDEMD 150
O17716        99 IEIVQVLM--------AFYTSIYASTICMLAVQFVYRYWAIFNESLLHYFKGWRFLFSIAYSFIVGAQWGLSIYFFDEMD 170 Caenorhabditis ...
XP_002637697  96 IEIVTILM--------AFYTSIYASTICMLSVQFVYRYWAIFDETKLRFFKGWKFLFCVAYSVIVGAQWGLSMYFFNQMD 167
O62017        91 SWSRNIPL--------AGYTFFHSATMSLLSVHFIYRYWAVFDTNKLAYFNGCYSLIWFFYCAFFGFQYSLGTYFFLARD 162 Caenorhabditis ...
O17896        91 NFSMEWMM--------GIYTGLYSATICQLAIQFIYRYWALFDTPKIKYFHGWYYLIWVSYYSFFGVLWAFAVGHFFAMD 162 Caenorhabditis ...
O45809        88 NEIMKIGL--------VFFCGIYGSTICFISVQFLYRYWALFDAPKLIWFEGWMMSAWLIYSFGIGATWSIGIHYFLEND 159 Caenorhabditis ...
XP_002637694  88 NDVMKIGL--------VFFCGIYGSTVCFIAVQFMYRYWALFDAPKIKWFESWRILLWCCYSLSIGILWAGGIHWFLEID 159
P91984        88 KETAMILL--------AAYSSTYAATISLLAVQFVYRYWAIFHVRRLSFFNGIWILFWIFLAMMFGVDWSCSVYFLGMPD 159 Caenorhabditis ...
XP_002635229 166 DETTEYLRENILYHYNLKMKDVIYVGAFYWrTLENGKTELVISTAIAAVIMFSIKATSISVVCYYGFLSYRRI-SELPQE 244
4_pfamImport 151 EYARDYVREEMYEQYKVDSDKVALFVLLAY-GENNGTKFVRPQSLICIFGQMGIMSLQYMIMMICGILIYKQIkADLKET 229
6_pfamImport 151 AYADHYFRAEMHKRYRLNISEVACFSLVAY--NFDNT--PRWRNILCTISLFCIMLIQYTIIIYCATIMYLKMeEKLKLL 226
O17716       171 DYTDNYMRNEMWERYDINISQVAKMALVAY--NDDGS--IRWWNVCCIIDMTVFMIVQYSIVIYCAVVMYQKMeEKLQLV 246 Caenorhabditis ...
XP_002637697 168 DYTDHYMREELLYRYDLTITEIARLCLVSY--NEDGS--LRWRNNSSTIDMTIFMIVQYTIVIYCAIVMYQKMeEKLKML 243
O62017       163 EITDEYLREDMLLRYNANISELPAMAIVAYd-PVDGS--VRWRNVMGIFNICSIVNFQYAIMFYCGWSMHTKMeDKIKNF 239 Caenorhabditis ...
O17896       163 DFGREYLGGEILLRYERNITDIPVLGLIAY---EGNS--IRWRNVYGLSLMTLISTIQYSVILICGHQMYHGMrAKLSVL 237 Caenorhabditis ...
O45809       160 NFTLNYFENGVYDHYGWKLSAIPSFTFVIY--TERGA--IRWRNLACTIEMTMIIGLQYSIICFCGRKMSVGMkEKISML 235 Caenorhabditis ...
XP_002637694 160 DFSIDYFQQGVRQIYGLELSSIPGFTSVIY--TRKGD--VRWRNLMCTIEMTMIIGMQYMIICFCGRKMSTGMkEKISML 235
P91984       160 KVSEDYLRLEISDQYNLNITRLAYFSAVVY--DSEYH--IRWRSVMVMGSVSKVLSIQYAVMIFCGVRMHFKMaEKMEQF 235 Caenorhabditis ...
XP_002635229 245 GeSAFTKSLQKQLYKALVLQAMIPILFMYLPIGTFLMLPAFNVNIEsFSKLATLFYAVYPAVDPLPLFFVIDNYRYALK 323
4_pfamImport 230 T-MILNSKFQKQIFNALLYQLVAPSLLVHLPAVPLFFAPFFDMKFSfRTRVVVYFFSVYPLLDSLILLTVVSDYRLAVR 307
6_pfamImport 227 --SVSIRNLHRQFYKTLVIQIFTPTICLFSPLIFIIFHPLFNVEIVvPTGMLLCAITIYPAVDAIIIMYVVTDYRNAIK 303
O17716       247 --SASLRELHRQFFKTLIMQILSPTICLFAPVVFIIYLPIFNFEVSiPTGMFLCAFTLYPALDALIIMYIVKDYRKSAK 323 Caenorhabditis e...
XP_002637697 244 --SVSLRNLHKQFYKTLLLQIFTPTLCLFAPVVFIIYLPLFDLKISiPTGMFLCAFTLYPALDAMIVMYIVTDYRNAAK 320
O62017       240 --SETLRKHHKQFFKTLVLQITTPTIILFIPITIIIFLPLFHLDVSlPSGVMLCSFTLYPAADSFIVMFVVSEYKNTVK 316 Caenorhabditis e...
O17896       238 --SAQNRRLHKQFFRALVIQITAPTIILFCPVFFMIYAPFADLEMSfPSCIIQSGFTVYPALDSIIMMSCVSEYGRALK 314 Caenorhabditis e...
O45809       236 --SETSKRLHTQFFKALILQIVVPTILLFFPMIIIIYLPVFNLKFSfPTGILFSAFAIYPSIDIAIILYIVSDYRIAIK 312 Caenorhabditis e...
XP_002637694 236 --SETSRRLHTQFFKSLVLQIVVPTFLLFLPMIIIIYLPLFNLEFSfPTGILFSAFAIYPAIDIAIILYIVCDYRNAIK 312
P91984       236 --SITNRKMHKQLFKTLVVQITVPTFTIFMPVMFMFLIPFFDLQLGiPTGVLLCALSLYPFIDGLIVISIVSDYRKAAI 312 Caenorhabditis e...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap