Conserved Protein Domain Family
ZYG-11_interact

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pfam05884: ZYG-11_interact 
Interactor of ZYG-11
This family of proteins represents the protein product of the gene W03D8.9 which has been identified as an interactor of ZYG-11. ZYG-11 is the substrate-recognition subunit for a CUL-2 based complex that regulates cell division and embryonic development.
Statistics
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PSSM-Id: 368652
Aligned: 8 rows
Threshold Bit Score: 297.493
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFO91406       1 MPQDSSDGYERLaditea----aknegsELKHVIRDVIRHYSDLSSDLHDyyek-----------nlkkFPEVVDQTVND 65 
CAP31583      19 PALLANAGCTAD----------------ASEAGINMAVTTMQKFGRELEQ-------------------FPAEGRRLVEQ 63 
O44551        19 PALLANAGCVAL----------------ATEAGIDIAIATMQQFGRELEQ-------------------LPERGRRLAEQ 63  Caenorhabditis ...
1_pfamImport   1 PALLANADGQE-----------------AGRAGIHLAVNTMQKFGRELEQ-------------------FPIESKKLMEQ 44 
XP_002636857  33 PPADAGAGGTAPsqmg--------atdgQQDASIAFVTKTYANYVQDIQQaaegir--------qraavLQQEGPAQLQQ 96 
EFO83402      33 ppVDAGAGGEAPgggvsqmggavgvgggQEEASLGMVTNIYTKYAQDVQQavegeasggtsgvrqralaFQQEGPAQLQQ 112
Q20960         1 MPEDADNGYERLeditna----vknegtEVTHVLRDVIRNYSDLGHDLQEyydk-----------nlrkFPETVERTAND 65  Caenorhabditis ...
XP_002630631   1 MPQDASDGYERLtdiaea----aknegsELKHVLRDVYRNYSELGSDIHDyyek-----------nlkkLPETVGQTAND 65 
EFO91406      66 LYNSAvmlktrsdfsmifwFQQNF------KDNLNIFVDSMMDLSpPEKISGFNISKIFANSIFLLLISSMSLFIGSYIT 139
CAP31583      64 AMTSIsttnhrstltsasqRSARSrsghgeQDSFVRIINILVDMT-AGQTPSKPIIETFVLSSITLAVFSLSSLLGGYLL 142
O44551        64 AMSSIstvnhrskrssvsqRSSKSnsg-veEDSFVRIVNTLVDLS-PRQISSKPIIETFVLSSVILTVFSLSSLLGGYIL 141 Caenorhabditis ...
1_pfamImport  45 VLSSVssvnmataastrgsRSEAS------QDSFVRIVNTIADIS-PSKLPSKAIIETFVLSSVVLTAFSLSALLGGYLL 117
XP_002636857  97 LQSQI-------------------------QPQTQELISALQETQsPIGLPTSSVVEIFGWSSILLLGAGIASIVGGYLL 151
EFO83402     113 LQSQL-------------------------QPQTQELMSALQETQaPIGLATSSVVEIFGWSSILLLGAGIASIVGGYVL 167
Q20960        66 VYH----------------FAQTF------KEDVNWFGNLMMNMSpPEKSSGFNISKTFANATFLLIVASISSFIGSYIT 123 Caenorhabditis ...
XP_002630631  66 LYS----------------FSQTF------KEDANKFLESMMELSpPEKISGFNISKLFANSIFLLVIATFSRCIGSYVT 123
EFO91406     140 APVFGIIFLNLGAVLVATIVIPVTASYvyhnlkvrSLA--EKRIACAGFIFI------QSVLIGFINQNDWLESSPYAVL 211
CAP31583     143 APFITLVIPPVGAAIFSALVAPAAVYY--------QLS--KGYGAIDGFRLLviaaaaQGVLTGAAFVHFTVPSEPFIAL 212
O44551       142 APFISFLIPPVGAAIFSGLVAPLAIYY--------QLS--TGYGPLNGFRLLviattvQGVLTGSALSHVLISAEPFVAL 211 Caenorhabditis ...
1_pfamImport 118 APFVTLIVPPVGAAIFSGLVAPLAVYY--------ELN--KGYTPLTGFRLLifaavaQGVLVGAALSHLQISGEPFVAL 187
XP_002636857 152 SPIFGIFIGRAGAAILATLVLPGLAAY--------QLNaeDGSTSATRFQLLlla-ltQGVLMGHAISYTYVSGQPLGFI 222
EFO83402     168 SPIFGIFVGRAGAAILATLVLPGLAAY--------QLNaeDGSTSATRFQLLlla-ltQGILMGHSISYTYVSGQPLSFI 238
Q20960       124 APVFGIIFLNLGAILVITIVIPLIASYvyynlrvrSLA--EKRIASCAFIFV------QSVLIGFINQDDWVESAPFTVF 195 Caenorhabditis ...
XP_002630631 124 APVFGIIFLNVGAIILVVIVVPIIATYvyrnlkvrSLA--EKRIACAGFIFL------QSALIGFINQNDWLESVPFSVL 195
EFO91406     212 TQIISSFVyplALAHTDN-RKKILGFVAGSIILFNVSHGFLASGMDGTFLTISILYTLLSISLIQysIAFRCLTD-FDMM 289
CAP31583     213 STIAASFA---IAMINPTsRSASLSTTFATSIIIHSSLGAIEGALTPIYFVLTGLYTLSALVPIQ--LATRDQGR-ANVN 286
O44551       212 STIASSFI---IAVMNPTsRASSLSTTVATSILIHSTLGAVEGALTPVYFVLTGFYTLAALIPIQ--LASRDQSR-ANVN 285 Caenorhabditis ...
1_pfamImport 188 SAIVSSFA---IAISGQTsRTALISITVATSLLIHSTLGAIEGALAPVYFVLVGLYTLAALVPIQ--LSARDQRR-ANVN 261
XP_002636857 223 TPLVIAFAyplVAGQVGTaHVPLLGGAVGASFAAQFVFGLVSGSLTFSYFLLSALYSAASGALLQ--IAFKNLNApSRIH 300
EFO83402     239 TPLVIAFAyplVAGQVGSaRVPLLGGAVGAAFGVQLMAGLVSGSLSFSYFMLAALYSAASGALLQ--IAFKNLSPpTRAH 316
Q20960       196 TQMIASFVypmVLIHTDN-RQKILGSVAGLSIFCHLFIGLIFSGINGPFLMMAVMYTVLAVALIQysIAFRTQTD-YDMM 273 Caenorhabditis ...
XP_002630631 196 TQIISSFSyplILAHTDN-RQKILGFVAGSSMIFHLAHGFFFSGMDGAFLTIVIMYTFLAICLIQysIAFRCQTD-FDMM 273
EFO91406     290 HSSMQYVLLISVSKMFVLMSLGNH 313
CAP31583     287 LYSAVLVGTTIASKCFVYGILGNS 310
O44551       286 LYSAILVGLTISAKCLVYGVLGAY 309 Caenorhabditis elegans
1_pfamImport 262 LYTAVLVGLTITAKCFVYGTLGAT 285
XP_002636857 301 MYQILLVASFLFSKALVYGLFGSA 324
EFO83402     317 MYQILLVASFLFSKALVYGLFGSA 340
Q20960       274 HLAMQYVFLVSGVKMFALMEFGTD 297 Caenorhabditis elegans
XP_002630631 274 LLTMQYVFLISVVRMFAFVSFGKE 297
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