4IX7


Conserved Protein Domain Family
BEN

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pfam10523: BEN 
BEN domain
The BEN domain is found in diverse animal proteins such as BANP/SMAR1, NAC1 and the Drosophila mod(mdg4) isoform C, in the chordopoxvirus virosomal protein E5R and in several proteins of polydnaviruses. Computational analysis suggests that the BEN domain mediates protein-DNA and protein-protein interactions during chromatin organization and transcription. The BEN domain-containing protein 3 (BEND3) is shown to interact (via BEN domains 1 and 3) with ERCC6L (via N-terminal TPR repeat and SNF2 HeliC region of ERCC6L) which stimulates the ERCC6L translocase and ATPase activities.
Statistics
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PSSM-Id: 463133
Aligned: 44 rows
Threshold Bit Score: 37.3561
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4IX7_B        29 LATRKLLVTIFDRETLATHSVTGKPSpafkdqdkplkrxLDPGKIQDIIFAVTHKCNA---------------SEKEVRN 93  fruit fly
OWR46560     312 IATRTLLLATFPRRILATHSLTGKRSpafqnk--pakmcLDPKIVSDIILEITSKFKV---------------KENLVRS 374
XP_004931730 322 KATRTLLLAVFPRRVLATHSLTGKRSpaflnk--ppklcLDQKIIADVIAEIIERFNV---------------KENLVRS 384
Q9VQD6       288 VATRCLLCVVFSSDELATHTLTGKPSpafygrerppklqLDQRKVDDIVVCVRNRTGG---------------KERVIRA 352 fruit fly
XP_001965203 290 SITRKLLCEIFDRDTLAHHTLSGKPSpafrdcarpskqqLDPLKVADLVYLMTNRMDM---------------TPREVRT 354
OCA20384     371 LMTRRLLDYFFSRETLARSSATGQRIahnntt-mekplrLPDKVVTAIKAYVTRACGR----------------GCNFNA 433
OWR44132     781 SLALRLLSAVFNRKALSVCLSIAERAqasdnvrsnarpeLDDHAATVLLNFVLDHGLQrgw----------ntDLRPILS 850
XP_012549861 430 TLARMLLLEIFTKNALSVCSLTGKKAnafeg---pirpgLDEHARTVLLNYVKKYAAEknw---------adfDRQLVVN 497
BAC31373     312 LLFRKLVCAFFDDKTLANSLPNGKRKrgfnd----nrkgLDQNIVGAIKVFTENYCTAnhvdklpgprdwvqiLQDQIKL 387
XP_021328908 308 LLFRKLVCAFFDDTTLANSLPNGKRKrglnd----trkgLDQNIVGAIKvftEKYCTAngieklpgprdwvqiLQDQIKL 383 zebrafish
4IX7_B        94 AITTKC 99  fruit fly
OWR46560     375 IITTKC 380
XP_004931730 385 IITTKC 390
Q9VQD6       353 TITTKC 358 fruit fly
XP_001965203 355 AITTKC 360
OCA20384     434 VINSKC 439
OWR44132     851 TLHSKI 856
XP_012549861 498 SIRNKM 503
BAC31373     388 ARRRLK 393
XP_021328908 384 ARRRLK 389 zebrafish
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