Conserved Protein Domain Family
ERO1

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COG5061: ERO1 
Oxidoreductin, endoplasmic reticulum membrane-associated protein involved in disulfide bond formation [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
Statistics
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PSSM-Id: 227393
Aligned: 4 rows
Threshold Bit Score: 420.448
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
19075813   8 AKGLVGLLILYKnvcqvlcksgssvksgSPWSIKNDGKSIIHDTLNSSYSdIENLNSRVSPLLFDLTEkSDYMRFYRLNL 87  fission yeast
19074095   1 ------------------------------------------------------------------------MFWVWASL 8   Encephalitozoon cun...
19112908   1 MIGITKLISIWN----------------AIWNFLLLPEIIISQTDTSSTG-IYQMQSKVRSLVPVLTErSDYFSYYRVNL 63  fission yeast
2497059    8 ATLCLTAFTSATsnnsyiatdqtqnafnDTHFCKVDRNDHVSPSCNVTFNeLNAINENIRDDLSALLK-SDFFKYFRLDL 86  baker's yeast
19075813  88 FNKECRYNLDDNVACGSSACNVLVTDEQD-VPEVWSSkslgKLEGFMPelsrqivetdrsvmeHVDKISQSCLLERLDDE 166 fission yeast
19074095   9 LAAAVTLEPDRIDMSVSKINNTTYRSLEGlVSK---D----SYSLVKT-----------------KDLGDFPSESKCTLL 64  Encephalitozoon cun...
19112908  64 YRSSCPLWENDNAMCSNQGCAVKSLNEIE-IPKVWK-----KLSDFEP---------------HSKKNDTKCNWKYNPDL 122 fission yeast
2497059   87 Y-KQCSFWDANDGLCLNRACSVDVVEDWDtLPEYWQPe---ILGSFNNdtmkea----ddsddECKFLDQLCQTSKKPVD 158 baker's yeast
19075813 167 Ah---qYCYVDNELDSG-CVYVSLLENPERFTGYSGPH-STRIWEMIYNQCLPDSSAPtidfpalfmqgplaPppkpqeq 241 fission yeast
19074095  65 S------CFTKKKSIFN-DEYINLLETREAYTGYKTNTgSAEIWRKIWEISREDTLLP---------------------- 115 Encephalitozoon cun...
19112908 123 D-----YCYLDNSTSPDeYVYVSLVQNPERFTGYAGDH-SAAIWRSIYEQNCFVVDDDdnpseqpksnalfrPnqiplnl 196 fission yeast
2497059  159 IedtinYCDVNDFNGKN-AVLIDLTANPERFTGYGGKQ-AGQIWSTIYQDNCFTIGET--------------G------- 215 baker's yeast
19075813 242 llkermdaWT------LEQRVFYRVLSGMHSSISTHLCHGYLNQRNGVWGPNLQCFQEKVLNYPERLENLYFAYALMQRA 315 fission yeast
19074095 116 --------T---------------LVSGLQFSILTHLSSFHRN-FFGTYLPNPVLFRKRFRDNHR--LNFYLTYFLVRSC 169 Encephalitozoon cun...
19112908 197 ftenhddtSLspsvacLEKRMFNRIISGFHASISTHVCQNYYDVEEQRWTQNLDWWRAKVGSFPDRIENIFFNYALLHQA 276 fission yeast
2497059  216 --------ES------LAKDAFYRLVSGFHASIGTHLSKEYLNTKTGKWEPNLDLFMARIGNFPDRVTNMYFNYAVVAKA 281 baker's yeast
19075813 316 IDKLYGHLD------SLTFCHDSVLqdsEVRQKIAGLVSLIHNSPKMFDETMLFAGDPSIStaLKEDFREHFKTVSALMD 389 fission yeast
19074095 170 VGNIDVDQS-------------------ELSGGLSSIIHAIRAQGSTNWVIQPVDLEKSIQ-----RVDEMIR----LLK 221 Encephalitozoon cun...
19112908 277 LVQIATQMKnitsdsSFTFCPTDKDvdwRTHTAFEQLVYHAYQDRHVINREQFFADEEAKR--FKDSFRKHFRDISRIMD 354 fission yeast
2497059  282 LWKIQPYLP------EFSFCDLVNK---EIKNKMDNVISQLDT--KIFNEDLVFANDLSLT--LKDEFRSRFKNVTKIMD 348 baker's yeast
19075813 390 CVGCERCRLWGKIQTNGFGTALKILFEVsniedEVTNFDsrsfslrLRRSEIVALINTFDRLSRSINfvddfkq------ 463 fission yeast
19074095 222 YVNCEKCQLWGTIQLKGLRAALKVFSGS------T---D-------LESLERFFLVNFFMRLSVSVR------------- 272 Encephalitozoon cun...
19112908 355 CVGCDKCRLWGKVQITGYGTALKLLLEP-----ETQLSD-------LRPEEVVALVNTFDRISHSV-------------- 408 fission yeast
2497059  349 CVQCDRCRLWGKIQTTGYATALKILFEIn----DADEFTkqhivgkLTKYELIALLQTFGRLSESIEsvnmfekmygkrl 424 baker's yeast
19075813 464 ----iyseqhkPASFKRRVLRRIKQLLFSVTPV----------------ALHPFLQKTSSILVd----lYFDFKAEWDnv 519 fission yeast
19074095 273 ---------------ENIKLRSYRAPLLVTASL----------------YWLEMLSSAASLLM------IFLVSRARS-- 313 Encephalitozoon cun...
19112908 409 -----------EATFWFSLKAKTNDTLDAIKAL----------------IYKTYRSPSKEILA-------FFIDQTWY-- 452 fission yeast
2497059  425 ngsenrlssffQNNFFNILKEAGKSIRYTIENInstkegkkktnnsqshVFDDLKMPKAEIVPrpsngtVNKWKKAWNte 504 baker's yeast
19075813 520 m----lgFRYVFASYLRFPRLF 537 fission yeast
19074095 314 ----------KFKSRIALKSCM 325 Encephalitozoon cuniculi
19112908 453 -------LFYALFFICNVPRVI 467 fission yeast
2497059  505 vnnvleaFRFIYRSYLDLPRNI 526 baker's yeast
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