Conserved Protein Domain Family
DUF2009

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pfam09418: DUF2009 
Protein of unknown function (DUF2009)
This is a eukaryotic family of proteins with unknown function.
Statistics
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PSSM-Id: 401392
Aligned: 40 rows
Threshold Bit Score: 581.056
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_004180058             156 SFIPMRLTYEERYLLKLLEATLEVSEYTNNVDILSYE-SKTKRIVKQLKELCSILSGLVIASNF---KIGLKLIENKE-Y 230
WGS:AAFB:cds.EHI_148780A 146 RFIPLRITQPERKMLRLLEASLHVSKYSDKVDQIKLI-GKPQRLQEQLKGIASLLNGILIATQP---SEKEDYSDVLNtF 221
CAM72770                   4 sqYPLRLTDLERQKLQLIVAALKVSEYTDDVDDFMRPyGKEGRMEAAMREFIDIVVGLAIASDAiprSVKNSFLAGEVkV 83 
Q4CS98                     4 eNVLLRLTDTEREDLQLLIAALKVSEYTDDVDDIRHPnSREERMYRCMRELFDTTLGLCIASGSvsrEVREEVARGNTdV 83  Try...
Q383U1                     4 ESVLLRLSDEEREELQLLIAALNVSEYTDDVDDIRRLsARDDRMCRCIRELFDTVLGLYVASGRvprEMKEGIASGRAsT 83  Try...
XP_001469225              34 EHIPLRLSPQERKIQRLMRGVILASSYTDKVDSASAL-KLKNRELLIVKELTNALTGLIVGLDM---RKAASFMRDHE-F 108
Q4E4V2                    31 DYIPLRLNPRERKIQRLMRAVIMASHYTDKVDNEAVL-KSNKRDAIIVKEITNSLSGLITGLDV---EKGAKLLREKD-F 105 Try...
Q38DU7                    30 DYIPLRLNPKERKVQRLMRGIVMASHYTDKVDNESTL-KGNKRDSVIVKEVTSALSGLIVGLDV---EKGGALYRDKD-F 104 Try...
EFC40866                  20 KYIPIRLTFEERKKLRLLEATLTVSEYTDKIDTIRTF-GKLKRIKEQCEEICAILCGLMVAADY---QKGQELIANKN-F 94 
EFA84037                 370 KYIPVRLSLQERNLLRLLEASLHVSEYTDKVDIQISN--RPKRINDQLRHICAILCGLLVASDF---KKGQQLVEKKD-F 443
XP_004180058             231 KKFSNWFKKIFEIGRRYKIMNPEKMKSNYGKLVYILMDSMLPE-IESIMEF--NLYKPINTIESFLiennskntDNNEIY 307
WGS:AAFB:cds.EHI_148780A 222 SQHEDILQAIFEIGRRYKIMNPDRMRDDYAKLIFILQDITVNS-INEELGV--SLLRPVETVYRYL--------ERKDLL 290
CAM72770                  84 ATVVPLLEDLFEIMRRHKRLNPFSHRGEFGKLMMMLQDVQKRS-IQRALEIqsTLVIPVRTVEAAL--------SSIHCE 154
Q4CS98                    84 RLTISILIGLFEIFRRHKRLNPFSNRSEFGKLTMLLQDVQKRS-IQERLHIshSLLIPVQTVGMEL--------RRVGAE 154 Try...
Q383U1                    84 QMTLKILPSLFEIFRRHKRLNPFSNRSEFGKLTMLLQDLRKPT-VQQRLEIchSLIIPVKTVGGEL--------QRVGAE 154 Try...
XP_001469225             109 TPYQHEIRAAIEMCRRYKMMNPDLLRTDYVKFLYMIQDAVQSDmAREALGF--NVVKELVTVGRYC--------ETHNMQ 178
Q4E4V2                   106 SPFAREIQLAVEASRRYKMMNPDFLRTDYVKFLYMVQDAVQNEnVREMLGF--VVAEQIVTVGFYC--------RALGFE 175 Try...
Q38DU7                   105 TPFARDIQSAVETYRRYKMMNPDLIRTDYVKFLYMIQDAVQNQnVKEALGF--PVAERIITVGRYC--------SYLGVE 174 Try...
EFC40866                  95 QDNEEFFQDVFEIGRRYKIMNPEKMRGTYGKLCYIIQDSQQPE-VQEMLGF--KLDRPVKTVHWFL--------EQHDAL 163
EFA84037                 444 SDNEMFFQTVFEIGRRHKIMNPAKMRAEYGKMIHLLQDSSQRE-IRDALGL--ELVSDLKTVYAVL--------EECDGL 512
XP_004180058             308 QMFRDNLILDATSYISSIGKTRTQINKLIKKKESAIETLANKYGKINgFDDEKIRQIIYSIDDFNTYTFMNRTPILRMQR 387
WGS:AAFB:cds.EHI_148780A 291 KILDDELIEIAVSEIIPDNKSKSQIQDEIKRKENAIKVIAKKYSTMN-CDEEEIKQCLYSIADNNCYLRYNRDPVVKTIH 369
CAM72770                 155 TLADDEAVRT------------DYLKRTGTEKQAGMQSLIERYSKGDgHKKEIIEHCLRSIDDVYSFIQSNTRPLRTLRR 222
Q4CS98                   155 ELLTDRDVD-------------KYLVTHGTEKAAVLQKLLDRYGGs--ECKPVVERCLRSIDDVSQFIEGNVRPLRWLRQ 219 Try...
Q383U1                   155 AMLRDPDLG-------------EYLNSFDKNKVTAFDRLLGRYGG---AESSTVERCLRSIDDVHQFLESNIRPLVWMRN 218 Try...
XP_001469225             179 DILQDTRLPHCITPV-PVMKDRNMLNRCLRGKDVVVGKLVKQYASEHrMHEDNVEVVVRSLNDANCFSNDNVETSERLLE 257
Q4E4V2                   176 SILQDNRMPLCITPV-PFIKNRNKLNKALRHKDVTVNGLLKEYSRASgRTLDEVEIAVRSLNDANHFANDNVDSTNQMLH 254 Try...
Q38DU7                   175 DMLQDKRLPLCITPV-PFMKKRSKLNEALRRKDVTVSSVVKEYSRKSgRSQDEVEIAIRSLNDANQFANENVESTNELLN 253 Try...
EFC40866                 164 EILEDKDIDTATNEIFANGKTRMQVEEEIKMKEKAAKRICKVYSESCeMEEEDIEKCLYSIGDSSAYLRQAVYPVETILS 243
EFA84037                 513 KLLSDPLLDVATREVLPDGKQRHEIQHDIKVKERAIKMLSNKYASST-LSTDQIEQCIYSIGDNHTYLRENRDSVRKMIK 591
XP_004180058             388 RLDLFLEPEIMKKY--PIGIKYGRGGSKLTHDHSKQYHYVQQSLMIWSIVQREMIHLWYLADLD-LFS-TTHYQLANTGH 463
WGS:AAFB:cds.EHI_148780A 370 YLEKYFDPNEAKEPrfSLAINEGNEGSRLSHDHAKQFLFVKQTLVLWNIILENMYQLWILAELD-LFDpQHPYEMKNTGQ 448
CAM72770                 223 WLSRDFEPLPSDNAy-SISIRHGRSGACFTHSHATHCQYVTESLLLWENVQKNILNLWEAAEDDmLVEgQGQYVVANTGQ 301
Q4CS98                   220 IILEEFLPLDGNPKy-DLSIRAGVNGAKFSHDHKRHCQYVVESLTLWENVQRNIFDFWQVSEDDmLIDgDGHYTFVNTGQ 298 Try...
Q383U1                   219 IISEEFCPLDKNCKy-NLAIQQGVDGSLLTHEHSVQCAYVIESLSLWIKVQQSIFEFWQVSEDDmLIDgSGQYSLVNTGQ 297 Try...
XP_001469225             258 LLKQYFTPISCTELt-SLAIDEGADGSRLTHNHKMQYIFVLQSLSLWKNMCRKMYLLWSLAEED-MLNpNEKYELRMTGQ 335
Q4E4V2                   255 LLKEFFSPDAPTDLt-NLSIEEGENGSRLSHNHRRQYFFVLQSLSLWKNICRRMFSLWTIAEGD-MLNpNEPYEFRYTGQ 332 Try...
Q38DU7                   254 LLLQHFSPNNVTEAt-DLNIVEGEGGSRLTHNHRRQYFFVLQSLSLWKNICRRMFSLWTIAEED-MLNpNEPYEFRSTGQ 331 Try...
EFC40866                 244 FLLNNFKRDDYEDGh-SLAIMAGHEGARLSHNHAIQFDFVYQTLTLWKNVGRDMFELWFLAERD-LFSsTHTYSLRNTGQ 321
EFA84037                 592 YLKTYFDPENEEQYf-SLRITPGQAGARLNHSHQKQYMYVYQSLTLWKKILHDMFRLWYLAEYD-LLR-GNSYSLRNTGQ 668
XP_004180058             464 GLNRIKACPLIYKEMVKIIGECKMSSK-EWIGSSVIHLGDHAVPNALFFLDKYIQIPNILMPFDNTINKIDEYVSh---- 538
WGS:AAFB:cds.EHI_148780A 449 GYHRLQQSPRISLVMHRIVKEMQEKVG-NWVGSAQIHLGDHNVPNALVFIDKYTQISRFLGPIITTLENLEKIGEk---- 523
CAM72770                 302 GFHRMCSAPRSYGVMSRLVRDTEQRMG-GWVGIKVIHLGDRDVPNPLVFIDKYTVIPRLVKPVVQTLHALRYVFHeedee 380
Q4CS98                   299 GFHRMCRAPKSYSRMARCVNEADQEMG-GWVGIKVIHLGDRDVPNPLVFIDKYTVIPRIVQPIMHTIMEIEKIFSpss-- 375 Try...
Q383U1                   298 GYHRLCHARKSYARMSRVVNETEHQLG-RWIGIKVIHLGDRDVPNPLVFIDKYTVIPRIVQPIMHVMMALEKIFSpda-- 374 Try...
XP_001469225             336 GLQRVQKAPQLFKAIQQVLQETKEELG-EWVGSERIHLGDDQVPNAFHFIDKYGQVSRIIIPILRTLGHIDHLER----- 409
Q4E4V2                   333 GYQRVQKAPNLYRAISEVVQQTKDELG-EWVGSDRIHLGDDQVPNAFHFIDKYAQVSRIIIPILRTIAHIDTLAE----- 406 Try...
Q38DU7                   332 GYQRVQKAPNLYNAIHEVVQETKKELG-EWVGSERIHLGDDQVPNAFHFIDKYGQVSRIIIPILRTVSHIDKLEE----- 405 Try...
EFC40866                 322 GLNRVQYCPNVRRAMEKLLSQTQNSTS-SWVGSSVIHLGDDAVPNSLMFIDKYTQISRILNPIIQTITEIDNYMIk---- 396
EFA84037                 669 GLNRIQAAPKISSAMGKILHSAQTKVGqYWVGSSVVHLGDHNVPNALTFIDKYTQISRILNPIVIAIDFIPKIK------ 742
XP_004180058             539 -------------DVFFSEYITKEYGSTKDLKLIILQDSFTHMFDGSGADNFFMSGSCIDGRLTSAWNFCNELSKKKYYN 605
WGS:AAFB:cds.EHI_148780A 524 -------------NAHVKNYIIKTFGSYEELRMIILTDFFKHAFDGSGADNFYDAGSCIDGRLTSAWNWCSSVDKKEYYP 590
CAM72770                 381 eegqpqvvheydnYPGLRNLLRSKYHSYGELMMMILSDFFKHAFDGSGDD----GGSCIDGRLTSAWNWCHQLHKKKYYD 456
Q4CS98                   376 ----------peeHPGLRNFFRAKFNSYKALRMMILSDFFRHAFDGSGDD----GGSCIDGRLTSAWNWCHQLEKKSYYD 441 Try...
Q383U1                   375 ----------keeHPGVRNFLRSKYSSFPELRMTILSDFFRHAFDGSGDD----GGNCIDGRLTSAWNWCHQLHKKSFYD 440 Try...
XP_001469225             410 -------------HAEHAAYLREVWGGGEQAKRAILRDFFRHGFDGSGGDNMDDAGSCIDGRLTSAWNWCNNIRFKEFYP 476
Q4E4V2                   407 -------------SYEHNAYMKEVWDGSMNAKRAILRDFFRHGFDGSGGDNMDDAGSCVDGRLTSAWNWCNNIRWKPFYP 473 Try...
Q38DU7                   406 -------------SPEHKAYVKEIWGSPTGAKLAILRDFFRHGFDGSGGDNMDDAGSCVDGRLTSAWNWCNSIRFKPFYP 472 Try...
EFC40866                 397 -------------DQNLKEYINTTFGGPEEAKMTILIDLFRHGFDGSGADNFFMAGSCIDGRLTSAWNFCSKINKKNYFP 463
EFA84037                 743 -------------DPGLQTYILNTFGSQKNLVKLILSDFFKHAFDGSGADNFFDAGSCIDGRLTSAWNWCSKIEKKNYYS 809
XP_004180058             606 IFLLTGFTGFNG 617
WGS:AAFB:cds.EHI_148780A 591 IFQLAGFTGFDG 602
CAM72770                 457 AFVLTGFAGFD- 467
Q4CS98                   442 AFVLTGFSGFD- 452 Trypanosoma cruzi
Q383U1                   441 AFVLTGFNGFD- 451 Trypanosoma brucei
XP_001469225             477 LFLFSGFSSFDG 488
Q4E4V2                   474 LFLLAGFSSFDG 485 Trypanosoma cruzi
Q38DU7                   473 LFLLAGFSSFDG 484 Trypanosoma brucei
EFC40866                 464 LFLLGGFIGFDG 475
EFA84037                 810 IFLLSGFNGFDG 821
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