Conserved Protein Domain Family
UBA_atDRM2_like
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cd14330: UBA_atDRM2_like 
UBA domain found in Arabidopsis thaliana DNA (cytosine-5)-methyltransferase DRM2 (atDRM2) and similar proteins
atDRM2, also called protein domains rearranged methylase 2, is a homolog of the mammalian de novo methyltransferase DNMT3. It is the major de novo methyltransferase targeted to DNA by small interfering RNAs (siRNAs) in the RNA-directed DNA methylation (RdDM) pathway in Arabidopsis thaliana. atDRM2 is a part of the RdDM effector complex and plays a catalytic role in RdDM. It contains an N-terminal UBA domains and a C-terminal methyltransferase domain, both of which are required for normal RdDM.
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Statistics
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PSSM-Id: 270515
Aligned: 7 rows
Threshold Bit Score: 56.298
Created: 17-Apr-2013
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9M548        195 GSKIRSLVKMGFsELEASLAVERCGen-vdIAELTDFLCA 233  Arabidopsis thaliana
NP_001065954  125 DEKIKSLVSMGFpEDEAMRAITRCG-----LDASVDLLVE 159  Japanese rice
XP_001610444 1498 EEVRSTLIDMGFlDNDITRALDHCGyt--dVSVLADWLLD 1535 Babesia bovis T2Bo
XP_002172591    9 SVHLETLKSMGMsDEDARESLRRCQn---dVANAADYFFS 45   Schizosaccharomyces japonicus yFS275
Q10187          5 DTKIKTLKNMGVsESDAKDSLERCGy---dVESAAEFIFS 41   Schizosaccharomyces pombe 972h-
EIE20769      302 EVAVASLVSMGFpESDARQALERCAgssdvLQAAMEYLFS 341  Coccomyxa sp. C-169
XP_002504732  291 PGAVETLTSMGFdEHDARRALGMCGn---dVEAATDALLA 327  Micromonas sp. RCC299
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