P47085   5 PATHAGSWYSNRAQELSQQLHTYLIKSTLKGPIh---nARIIi-------cPHAGYRYCGPTMAYSYASLDLN---RNVK 71  Saccharomyces cerevis...
Q57846   6 YPAVAGLFYPSHPDELIDMIEQCYLHKFGPKSMpvhgtYEKPigl----lcPHAGYVYSGPIQAHSYYELSKRvdaLEET 81  Methanocaldococcus ja...
O27974   3 HPRVAGSFYPANPESLLAMLR---EYTYPAKd------ESVIac-----vsPHAGYVYSGRTAGKVHSLLPD----A--E 62  Archaeoglobus fulgidu...
P95994   4 LPAVAGSFYESDPKKLKMQIEWSFRHNIGPRDIpk-qsYEKKkrdnlffivPHAGYIYSGPVAAHSYYYLASe---GKPD 79  Saccharolobus solfata...
O26151   4 RPAVAGAFYERDPAALRRRIEWCFEHELGPGTLpavgsMRRIkgv----iaPHAGYMYSGPVAAHAYHELVSd---GIPG 76  Methanothermobacter t...
O67039   5 EPAVAGTFYPKDKEELNKLMD--LLCGFEP--------KEKIkpka--ilvPHAGYIYSGKTACEVYKRIEI----P--E 66  Aquifex aeolicus VF5
O67355 104 EPSHAGQAYPENPQELKNFIEETVNKNSEKFK------ARGIl-------vPHMDLRVASGVYGSVYSAIKE----NEYD 166 Aquifex aeolicus VF5
Q56419  60 PMRLAGLSYPEGEREARAFLEAFRASYPGEGEE-----ARVLl-------mPHLEPSRVPEVYGAALAALEKT---PPPE 124 Thermus thermophilus HB8
Q22915  60 SASHAGSWYNANQRDLDRQLT-KWLDNAGPRig----tARALi-------sPHAGYSYCGETAAYAFKQVVS----SAVE 123 Caenorhabditis elegans
Q10212   7 EATHAGSWYLDDTELLTKQLKSFIKNPTPETG------KRFVi-------sPHAGYMYSGKVASQGFQQLDF----SKIQ 69  Schizosaccharomyces p...

P47085  72 RIFILGPSHHIYFkNQILVSAfSELETPLGNLKVDTDLCKTLIQKEYPengkklFKPMDHDTdMAEHSLEMQLPMLVETL 151 Saccharomyces cerevis...
Q57846  82 TVVILGPNHTGLG-SGVSVMD-GIWRTPLGDVKCDEEFVEELWRKCEI------VDLDETAH-LNEHSIEVQLPFLKHLE 152 Methanocaldococcus ja...
O27974  63 TFVIVGPNHTGYG-LPVAVST-DTWLTPLGEVEVDTEFVEAMPK--II------TAPDEIAH-RYEHSLEVQVPFLQYLH 131 Archaeoglobus fulgidu...
P95994  80 VVIILGPNHTGLG-SYVSAWPkGEWETPLGSVKVDEEVLMQLVMESEV------IDLEEKSH-LYEHSIEVQLPFLQYFF 151 Saccharolobus solfata...
O26151  77 TLVIICPNHTGMG-SGVSLMQqGAWETPLGTVEIDSELAEAIVRESGI------IDLDETAH-LAEHSCEVHVPFIQYFT 148 Methanothermobacter t...
O67039  67 KVVLLGPNHTGLG-KPISVYSgDAWETPYGVVEIDGELREKILKY-PY------ANPDEYAH-LYEHSLEVQLPFLQRYA 137 Aquifex aeolicus VF5
O67355 167 TVVLLGVSHYFHE-TPFSVLP-LDLRTPLGDLKVDIERVEELQKMFDY------DLSHDVLAyKNEHSIEFQTIFLKYLF 238 Aquifex aeolicus VF5
Q56419 125 RIYLVGVAHRPLK-EKAAALP-VPFQTPFGPALPDLPALQALDALLPF------ELFNTPLAfREEHSLELPLFFLKGRF 196 Thermus thermophilus HB8
Q22915 124 RVFILGPSHVVAL-NGCAITTcSKYRTPLGDLIVDHKINEELRATRHF------DLMDRRDE-ESEHSIEMQLPFIAKVM 195 Caenorhabditis elegans
Q10212  70 RVFVFGPSHHIFT-RKCLVSRaSICSTPLGDLKVDEDLCQKLVASDNS------FDSMTLDVdESEHSLEMQFPLLAFHL 142 Schizosaccharomyces p...

P47085 152 KWReisldtVKVFPMMVSHNSVDVDRCIGNILSEYIKDPN---NLFIVSSDFCHWGrrfqytgyvgskeelndaiqeete 228 Saccharomyces cerevis...
Q57846 153 LLNia---kFKIVPICMMFQDYETAVEVGYFIAKIAKELNr-rIVVIASSDLTHYE------------------------ 204 Methanocaldococcus ja...
O27974 132 DD-------FKIVPICLGMQDEETAMEVAEEILTAERETGr-kVVVIASSDMHHYL------------------------ 179 Archaeoglobus fulgidu...
P95994 152 DDN------FKIVPIVIMMQTPEIAEFLADAIYKVIQKYSdkdIVVLASSDMNHYD------------------------ 201 Saccharolobus solfata...
O26151 149 DN-------FRIVPVTMWMQGHETAADVGHAVASAIRETGr-dAAVIASTDFTHYS------------------------ 196 Methanothermobacter t...
O67039 138 RRe------FKILPIVVTFVEYEVAKDFGRFLGEVLKEED---ALIVISSDMSHYV------------------------ 184 Aquifex aeolicus VF5
O67355 239 PE-------VKVIPAIVSYGDTKSLKEIAHKITKVLEDSQn--PLIISSVDFSHVGrkf--------------------- 288 Aquifex aeolicus VF5
Q56419 197 PEA-------RVLPLLVARRSPE----LGEALKVVLRDFP---GLLVLAVDLSHVGprfg-------------------- 242 Thermus thermophilus HB8
Q22915 196 GSk-----rYTIVPVLVGSLPGSRQQTYGNIFAHYMEDPR---NLFVISSDFCHWGerfsfs------------------ 249 Caenorhabditis elegans
Q10212 143 LKQgcl-gkVKIVPIMIGALTSTTMMAAAKFLSQYIKDES---NSFVISSDFCHWGrrfgytlylndtnql--------e 210 Schizosaccharomyces p...

P47085 229 vemltarsklshhQVPIWQSIeimDRYAMKTLSDTpngeRYDAWKQYLEITGNT-ICGEKPISVILSALSKIRDagpsgI 307 Saccharomyces cerevis...
Q57846 205 -------------PQEIASKK---DAIVIKDILEM----NEKELYEDVVNYNIS-MCGYGPVIAMLKAMKTLGA-----E 258 Methanocaldococcus ja...
O27974 180 -------------PDEECRRL---DSIVIDAILSM----DVKKYYETIYRLQAS-VCGYGCIAVAMYYSKAKG------A 232 Archaeoglobus fulgidu...
P95994 202 -------------PHEITMKK---DEEAIEKIQQL----DYRGLYEVVEGKDVT-LCGYGPIMVSLILAKKLG------K 254 Saccharolobus solfata...
O26151 197 -------------PQDIAEAT---DRRIIDRITAM----DDTGMYGVISELNAT-MCGYGPVAATIIASRILGA-----T 250 Methanothermobacter t...
O67039 185 -------------PAEEARKK---DEILISAMERL----NTEELYFKAVQYNIT-MCGVVPAVVGIESAKVLGA-----T 238 Aquifex aeolicus VF5
O67355 289 -----------gdPHSYDPSPr--DREYINLLAELk---NEEAFNLLQSDNNRTrIDGQFTNFVFLEILKNLGv-----K 347 Aquifex aeolicus VF5
Q56419 243 ---------dtplTRTLAEEArrrDLGFLERLAEG-----EPEAALAFLGANPTrIDGVEVVASLLPLLRERK------- 301 Thermus thermophilus HB8
Q22915 250 -------pydrhsSIPIYEQItnmDKQGMSAIETL----NPAAFNDYLKKTQNT-ICGRNPILIMLQAAEHFRIsnnhtH 317 Caenorhabditis elegans
Q10212 211 davlkykrrggptSPKIYESIsnlDHIGMKIIETK----SSDDFSEYLKTTQNT-ICGRYPIELIMKSMECANFs----E 281 Schizosaccharomyces p...

P47085 308 KFQWPNYSQSSHVTSIDDSSVSYASGY 334 Saccharomyces cerevisiae S288C
Q57846 259 KAKLLAYATSGDITGDYSAVVGYASAI 285 Methanocaldococcus jannaschii DSM 2661
O27974 233 RAELVDYSTSGDVA-DRSQVVGYAGIV 258 Archaeoglobus fulgidus DSM 4304
P95994 255 KAYILKHATSGDTSGPKDSVVGYLAAR 281 Saccharolobus solfataricus P2
O26151 251 ECDLLRYATSGDVTGDRSSVVGYAHLS 277 Methanothermobacter thermautotrophicus str. Delta H
O67039 239 KGIVVDYSNSGDTTGDYSQVVAYLGMI 265 Aquifex aeolicus VF5
O67355 348 EGKLLDYDVYHEAP--TDSKVSYAGMV 372 Aquifex aeolicus VF5
Q56419 302 -GKVLAHRLDLEAP--TLSAVGAGTLV 325 Thermus thermophilus HB8
Q22915 318 EFRFLHYTQSNKVRSSVDSSVSYASGV 344 Caenorhabditis elegans
Q10212 282 RFKFISYAQSSHVELVTDSSVSYATAT 308 Schizosaccharomyces pombe 972h-