Conserved Protein Domain Family
Cyto_heme_lyase

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pfam01265: Cyto_heme_lyase 
Cytochrome c/c1 heme lyase
Statistics
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PSSM-Id: 426167
Aligned: 56 rows
Threshold Bit Score: 278.435
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAP61752         1 MGWFWADA-TPAAPAVSKPlnhpqSGGDA-APPPG-CP-MHnkktvdafA-SAAPTPAAAPAPAPPAS-GCPVphsnPSa 74 
ybcl:Ecym_5037   1 MGWFWADSsVRERGGSESV---------EeSAVSG-CP-VIhs-----nSkTASGYPVVKEGTPAESS-SCPV------- 56 
Q758Z5           1 MGWFWADNqARPSAQRVQT------------SGQG-CP-VKhrd--estPgIVAA-----GGAAQEKA-ACPV------- 51  Eremothecium ...
P06182           1 MGWFWADQ--KTTGKDIGG--------AAvSSMSG-CP-VMhes--sssSpPSS---------------ECPV------- 44  Saccharomyces...
CCH61701         1 MGLFWATP-TNTDSNSNSStt--kTSGSKlELESN-CPyLKgkn--sskDnANVS--------------TTPF----ENi 56 
CCD26288         1 MGWFWADPnTQQNKSLWKA--------SSaTAISGqCP-VMher--keeS--ISACPVMRERKEEPVS-ACPV------- 59 
XP_002496642     1 MGWFWADPvVDHGSKVPSA--------SQaSSSSA-CP-VMhna--ssvKpETSA---------------CPV------- 46 
CCE65815         1 MGYFWATTiETESRSSSKS------------EASA-CP-VNhvt--kkvNdESAC-TVMHTSPKNDMP-ACPV------- 55 
EKC21297        31 ANTLQTQS-------------------SAqNYPSE-CP-MHkse---aaPqSFPSECPMHQKTTPSPPsGCPM------- 79 
XP_002053805     8 KVQMEAAK----------------SMSTGgSPPPE-CP-MHqk----ngGnQSASAVPPHPKMQAS---ECPV------- 55 
CAP61752        75 naalsscpvphgsAPEPTADNQQSFLSKLNPLNYMFHSISQER-APNQTHALPTSRDESSIPKG-----TGDGNWEYPSP 148
ybcl:Ecym_5037  57 ----------------IHQGGQNV---GLNPLNNVPSFISDRK-QPGQKLDLPTCRTTSSIPKGscdqmGKEEFWEYPSP 116
Q758Z5          52 ----------------MHDSGA------LNPLNNMP-NLSAHR-QAFQKLELPTERTVSSIPKGntdaaGEGEFWEYPSP 107 Eremothecium ...
P06182          45 ----------------MQGDND-----RINPLNNMP-ELAASK-QPGQKMDLPVDRTISSIPKSp----DSNEFWEYPSP 97  Saccharomyces...
CCH61701        57 l-----------qRQNNSISNEANNQDSLDPLNHLPKDLSLSE-LPGQSIDLPKERSISSIPKG-----NTNTLWEYPSP 119
CCD26288        60 ----------------MREKKQS----DLNPLNNIPFNLSSER-HDQQAIELPTERMISTIPRGt----KKKEYWEYPSP 114
XP_002496642    47 ----------------MQDSSASSGSDGLNPLNNMPVFLSANK-QQGQKLDLPTERTTSSIPKGd----NTHENWEYPSP 105
CCE65815        56 ----------------MHDSKNDTAT-GMNPLNHIPKALPVGK-QEGQKLDLPQERTVSSIPKGs----DSTEFWEYPSP 113
EKC21297        80 -------------------HEGGANEEEIDPRNMMPP--PNQRpSPDQPFPLSTDRVVSNIPKA-----DSDENWVYPSP 133
XP_002053805    56 ----------------------QHDNSDVNPLNMMPP--ANQQpSPDQPFPLPTDRQTSTIPKAte--dGTVQFWQYPSQ 109
CAP61752       149 QQMYNALLRKGY------TDTDVTAVESMVAVHNFLNEGAWGEIVEWERRFGKgllrgwevskrgEDNAdielrrleaqe 222
ybcl:Ecym_5037 117 QQMYNAMVRKGKvdpntgEEIPEDAVESMVFVHNYLNEGCWEEILDWEKPHIE------------ATAR----------- 173
Q758Z5         108 QQMYNAMVRKGKidpytgEEIPEDAVESMVYVHNYLNEGCWEEILDWERRYSE------------AAAA----------- 164 Eremothecium ...
P06182          98 QQMYNAMVRKGKig--gsGEVAEDAVESMVQVHNFLNEGCWQEVLEWEKPHTD------------ESHV----------- 152 Saccharomyces...
CCH61701       120 QQMYNAMVRKGKidvstgEEIEKETVISMVDVHNFLNEGCWDEILKWEKPYTE------------KSNY----------- 176
CCD26288       115 QQMYNAMIKKGKidsntgEEIPEDAVESMVYVHNLLNEGSWGEILKWEQPHTK------------ETLI----------- 171
XP_002496642   106 QQMYNAMLRKGKidpntgEEIPEDAVESMVQVHNFLNEGCWQEVLEWERPHTQ------------QTQV----------- 162
CCE65815       114 QQMYNAMIRKGKidpntgEEIPEDAVESMVFVHNFLNEGCWQEVLKWEKPYTD------------QTNV----------- 170
EKC21297       134 QMFWNAMLRKGWrw--keGDINKQDMDNIISIHNANNEQAWKEVLKWEALHAR------------ECS------------ 187
XP_002053805   110 QMFWNAMLRKGWrw--ktEDVTQKDMGDIIRIHNANNEQAWQEVLKWEALHAK------------ECG------------ 163
CAP61752       223 ggreQPTLIRFQGRPKEMTPKAAILQMLGRVYPSKFGTEPPFDRHDWFVSRN-----------------VNG-Q-QKEVR 283
ybcl:Ecym_5037 174 ----YPKLLKFMGKPSQVTPRARWYHLLGTLFPSKFCGELPFDRHDWIVLRPdpm------------stDTEnPgYRKVR 237
Q758Z5         165 ----HPKLLQFMGKPSQLTPRARWYHLLGTLFPSKFSAELPFDRHDWTILRPdpa------------asDPEhPgYRKVR 228 Eremothecium ...
P06182         153 ----QPKLLKFMGKPGVLSPRARWMHLCGLLFPSHFSQELPFDRHDWIVLRGer-------------kaEQQpPtFKEVR 215 Saccharomyces...
CCH61701       177 ----KPTLLKFIGKPDQYSPRAKAIHYLSMILPNHFSNELPFDRHDWFVLRKtdpntpidqgtttnasvDGVtPgFKVIR 252
CCD26288       172 ----EPKLLKFTGRPDKLSPRARWHHFLSNIFPSYYSNELPFDRHDWFVLRGdpnst-------ylddeGNEiSgYKRIR 240
XP_002496642   163 ----EPKLLKFTGKPGQLTPRARYYGILSKLFPNHFEGDPPFDRHDWLVLRAdpm------------saDPEnPgYRKIR 226
CCE65815       171 ----EPKLLRFQGKPNEMSPRAKFYNTLGKLFPNYFSSDPPFDRHDWVVLRAdpt------------stDKEhPgLREVR 234
EKC21297       188 ----EPRLKRFGGKAKEFSPRAKIRNWLGY--------SLPFDRHDWVVDRC-----------------------GKEVR 232
XP_002053805   164 ----NPRLKSFGGKAKDFSPRARFRSWLGY--------ELPFDRHDWIVDRC-----------------------GKDVR 208
CAP61752       284 YVIDFYSGP--PEPTGEPVFYLDVRPAI-TPTAAVERLMRW 321
ybcl:Ecym_5037 238 YVIDFYGGP--DDEEGLPTFNLDVRPALdNLGNAKDRFNRW 276
Q758Z5         229 YVIDFYAGP--DDENGLPTFNLDVRPGLdNVTNARDRFYRW 267 Eremothecium gossypii
P06182         216 YVLDFYGGP--DDENGMPTFHVDVRPALdSLDNAKDRMTRF 254 Saccharomyces cerevisiae S288C
CCH61701       253 YVIDFYGGP--DDKNGMPTFNLDVRPALdSLTNVCDRFNHQ 291
CCD26288       241 YVLDFYGAP--DDENGLPTFNIDVRPALdNFENTRDRFNHL 279
XP_002496642   227 YVIDFYGGA--DDEDGMPTFHLDVRPALdNVTNARDRFRHY 265
CCE65815       235 YVIDFYGGP--DDDDGLPTFNLDIRPALdNFTNSKDRLVHY 273
EKC21297       233 YIIDYYDIGevDKRT-YEFTALDVRPAFdSFSAVMDRSKVA 272
XP_002053805   209 YVIDYYDGGlvDKD--YRFALLDVRPAMdSVDNVWDRMRVA 247
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