Conserved Protein Domain Family
DUF4791

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pfam16039: DUF4791 
Domain of unknown function (DUF4791)
This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 189 and 203 amino acids in length. There are two conserved sequence motifs: PLPL and LGN. There is a single completely conserved residue N that may be functionally important.
Statistics
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PSSM-Id: 406447
Aligned: 27 rows
Threshold Bit Score: 121.969
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002051862         31 PQEHPFALAACVVGGLAAVFGLLRAFLddgsrrggggggrasnSssdGSEFR--MLRN-------VTQSMLELMPLALVN 101
WGS:AAPP:GF21789-PA  29 PAEHPYAFTACVIGFCHGLFGLVDFAA----------------G---GDTTK--SMKE-------TTTSMMEIIPLPLVN 80 
XP_001355655         28 PQEHPYAFTACVVGFCHGLLGLVATVS----------------G---DENTT--KAND-------ATNALMEIVPLPLVN 79 
EDW53256             28 PSEHPYAFTACVFGFCHGLFGLVSGLT----------------G---DDNAK--KVTE-------TTTSIMEIIPLPLVN 79 
XP_002028700          3 PLVQPFGYISCMMAYTHGTLGLIVSLR---------------------------KAGNyhcphmcLTRTLMEVGQVTLIN 55 
WGS:AANI:GJ13231-PA  26 PAEHPYGYTAAAFCFVHGLLSLVRALE----------------E---DEECSptRSFS-------VSTGIVDVIPLPLAN 79 
XP_001983705         24 PADQPYGYLAAAFCFIHGLISLVRTIQ----------------G---SEDCA--RSYF-------VSMAIVEVLPLPLAN 75 
XP_002071756         30 PGEHPYAFTGCVVGLCHGLLGLVNCFS----------------D---DSNVN--NAKE-------KSTSFMEIVPLPLIN 81 
EDV99833             28 PSEHPYAFSACVIGFCHGLFGLVDSFS----------------G---NETSK--SAKE-------TSNSILEIVPLPLVN 79 
XP_002011860         28 PQEHPFAFSACLIGFCHGLLGLIDIFV----------------G---NDNTH--KAKK-------TTNAIMEVVPLPLVN 79 
XP_002051862        102 MELYAHSLGl-GAVALAHGIFVL-PLLLDLRCSVVKNrKDCDlTE-------TLRDLLVLG--NIVSLGFLAAKERNLLY 170
WGS:AAPP:GF21789-PA  81 VDLYLGAES--NNIALGHGLFIV-PLAVSVILGMVKG-GDDGgEEsp---mgTLKTLTILG--NITSLLYLAINESSWNL 151
XP_001355655         80 VDLFMGADS--NNLALGHGLFIV-PLAVSVIIGWAKD-NDENgsv-----idALKTLTVLG--NITSMVYLALNESSWNL 148
EDW53256             80 VELYLAAES--NNIALGHGLFIV-PLAVSVILTFFKG---ESgDEseggaldTLKTLTILG--NITSLAYLAINESSWNL 151
XP_002028700         56 TELYNSSTGirRALAFGLSLGAIgFLAAKMPHVVFWR--------------------TVIGfcNIYSLTQRSQAERRSVF 115
WGS:AANI:GJ13231-PA  80 IEFYLQSSQ--SGMALVHALSLI-LLLYDMMGSLGDD-WDRA-TE-------TVKDLSLLG--NVASGAYLGTQEENYYH 145
XP_001983705         76 IEFYRQTSQ--CGLAFIHGISLI-LLLYDVMGSLGDD-GDRA-TD-------TVKDLTLVG--NIISGTYLGIQEEKYFH 141
XP_002071756         82 VDLYFGSAS--NNLALGHGLFIV-PMAVSALLGLFKD-ESEGqGEav----eTLKTLTILG--NITALLYLAINDGSWNL 151
EDV99833             80 IELFFGGDA--NNIALGHGLFIV-PMAICILVGLIQGkGDGEgDEvi----eTLKLLTILG--NITSLSYLAVNEGSWLM 150
XP_002011860         80 MELFFSGES--NNIALGHGLFIV-PMAISVLAGLIKG-EGEEvDEai----dTLKLLTMLG--NITSLCYLAINEGSMIM 149
XP_002051862        171 LRMTLTMLVVKYYPVLMDSAQ-EETGEDLIVCGNAYFLHVLGKV 213
WGS:AAPP:GF21789-PA 152 AGMAFLAFMAKFGAQFCDENVsEGSGEPITYISWSGFFVLAAMA 195
XP_001355655        149 GGMAFLAFMAKFGAAFFEENVsEGTGQPITYISWSGFFFLTALA 192
EDW53256            152 GGMAFLAFMAKFGAKFFEEQIsEGSGEPVNYLSWSGFYFLTAMA 195
XP_002028700        116 MLLALLNLAAYDGVDFIKRNFrRHYGESISKVCYIGITLLAVRI 159
WGS:AANI:GJ13231-PA 146 VGVAVSAGIARYGSSLVSTIV-PAAGPHVNTLSKAAIIGLMTYS 188
XP_001983705        142 VGAAASAGIARFGSHLVGYFL-PSAESHVDTLSRAAIIGLMTYS 184
XP_002071756        152 GGMAFLAFLAKFGAQYGEEQs-QGAGEPITYLSWTGFYILAAMA 194
EDV99833            151 GAMAFLSFMTKYGSEYLETQI-EGSGDPVKYVSWSVFYFLTTMV 193
XP_002011860        150 GGMAVLAFLTKIGSEYLETQI-EGSGDPVKYLSWSGFYLLATFA 192
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