Conserved Protein Domain Family
DUF4818

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pfam16089: DUF4818 
Domain of unknown function (DUF4818)
This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 176 and 214 amino acids in length. There is a single completely conserved residue W that may be functionally important.
Statistics
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PSSM-Id: 465013
Aligned: 29 rows
Threshold Bit Score: 89.962
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDX16356             32 AAPLLGAWLFSACVVTLLHGVRMFPSALPAdqrfrngnrnlrgnESSWASLLLETGVCCLVLDLTLSKLWHRIESLCQCA 111
WGS:AANI:GJ15517-PA  32 PGPTLPTIIVGVAILDLIYDYRIVPLSMYK--------------RARGIKYICECFVAILFLEVGMLIFWQTIEHLVYLI 97 
XP_001963392         30 PGPKLPSVMVTLALMDLIYDNSFVPEKLEG--------------VPRFLKWVYEVIVSVFVLDVGLH-FWKATEYTLYLL 94 
NP_001245542         29 PAPKLPSLFVGLAAMDIIWDNCFVPRKLQK--------------RSAVIRWIYELIVSHLLLGL-VQVFWKPVDNICVIL 93 
XP_002036021         29 PAPQLPSLIVGLAAMDLIWDTCLVPQELHN--------------LPAVIRRMYEVLVSYLLLGIAVQLFWKSVDFMCVIL 94 
EDX17193             29 PAPKLPSLIVGLAAMDLIWDINLVPRLLQN--------------SPAVIRRLYDVIVSYLLLGLFMG-FWKSVDNICVIL 93 
XP_001993114         32 PAPCQAKWLFGLSLVLLLWRCELLPKRYAS--------------VYPRIHTCVELLGSVFVSELAMLIGWCSYERLVHQL 97 
WGS:AAPP:GF22703-PA  31 PAPSLGAYLFLLAILFLLWDGDVIPKRYKK--------------SSPRLFAFVEILATVFITELIMLIGWCGYERMAFKT 96 
Q9VLE7               31 AAPPVGKYIFLLAILLLFWDSDMIPRKLKP--------------FSPRIFACGDLLFTIFFTEIILLVGWCGLERMTYRF 96  fruit fly
FlyBase:CG42592-PA   32 PAPKVGAWIFTFAILLLVADVRMCPKGYTH--------------VPYIIQVLGETVGSLIIIEFSTSVVWCALESVTHQL 97 
EDX16356            112 IVGIL-QALAVEEQTFLACEYWTLGLTTGLIGGCLLWLSLWATALPQKLRC 161
WGS:AANI:GJ15517-PA  98 AKMLLlEMDIVSLDYYYRHETFIIGSFTLPISLGILVLVSRITNHFKMLSR 148
XP_001963392         95 LKIIVlWMGYVSHLTYIEYEYYCQAAMTLPLAFLVLTFAGHATNHFHLVRG 145
NP_001245542         94 MRLIIlGTGIVSETNYENYESYWVGFLTVPLSLLILAIAGQATDHFSVLRA 144
XP_002036021         95 MRDIIlGNGLVSKIDYNNYESYWVGMITVPLSLLILGSAGHGIDYFHMLHD 145
EDX17193             94 LRILIiGTGHVSESNYENYESHWVGTVTVPLSLLILAFAGEATGHFPVLRR 144
XP_001993114         98 SHLIC----LNLNLNCRWCEYFTLGMLTLLPSGLLLFTLAPAQWREFLVQL 144
WGS:AAPP:GF22703-PA  97 ASMIC--------RQSEWCEYGLLIIITILGALITMCIVAEVVCPVKMKDT 139
Q9VLE7               97 IFSVC--------RGKPGCNYGLMTFCSILGAVGSLCIVLEVLTQRKMKNL 139 fruit fly
FlyBase:CG42592-PA   98 TRLLL-LYWGMNGDTYLALEYWILLIPTTAVASTFLYIMIKAIIpy----- 142
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