Conserved Protein Domain Family
DUF5578

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pfam17741: DUF5578 
Family of unknown function (DUF5578)
This is a family of unknown function found in Eukaryotes.
Statistics
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PSSM-Id: 436006
Aligned: 12 rows
Threshold Bit Score: 372.467
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
OAJ41570      91 RISLKPHCSASYFLQITSTWDKGNRSVREKILREFVASNDNKIGPQIEKEFGNGASLFLTRISAWLRLTYLLS-YDLALQ 169
XP_022525962   1 MSSSVDRAAGRRLLAFLREWDRGSERVRRRMLQTFLSQNTGKTSPELELEFSQAASLFLTRITVWIRLTYMFG-TSLDVQ 79 
XP_005479062  30 MSTQEQQANIGKVLSFLREWDRGDMRVRGRMLSTFVTQNTGKTFYELELEFAQVASLFLARLTTWMKLTYMLG-TFLGLQ 108
1_pfamImport   1 STQTDEQANIGRVLSFLREWDRGDGTVRGRMLNTFLTLNSGKTFYELELEFAQVASLFLARLTTWMKLTYTFG-TFLGIQ 79 
XP_019332640   1 MTSAKEQAAIGRLLAFLQEWDNAGRAARSRILDNFIEANQGKMGPELELEFSQGASLFLARLTAWLRLSYMNG-TCLDQL 79 
KFM12946       1 MTSVKEQEAIRKLMVFLQEWDSAHKVARSRILDNFIKSNDGKTEPELELEFSQGASLFLARLTAWLRMTYTYS-TCLNRL 79 
2_pfamImport   1 MTSIKEQAAISRLLGFLQDWDRADQATRLQILDNFIEINEGKTAPELEQEFSQGASLFLLRLSTWLRLSYPF--PCRGDL 78 
3_pfamImport   1 MLSIKEQEAVNRVMSFLQQWDHATKVQRTRILEDFINNSRGKNGPELEQDFAQVASLFLARLTAWLRLTYPHRiLLLYKL 80 
XP_016285295  40 MTSIKEQAAISRLLSFLQEWDKAGSVGRKNILERFIKLNSGKTGPELEQEFSQGASLFLMRLTTWLRLTYMNG-TCLEKL 118
XP_002591409   3 SGNAKTDAAINRVFGLLQEWDKGNKTTRGRILEEFIANNQGKTAPELELEFAQAASLFLTRLTAWIRLTYMLG-TCVNQQ 81 
XP_014777645   1 MRPANQEAQINRVFDLFKEWDKGDEATRKKILNCFIQQNKNKTGPELEMQFAEGASLMLARISAWLRLSYMFG-TALSEQ 79 
XP_009043770   1 MTSAKQLTAISRVINILQEWDKAPKTKRKTILEDFIKQHTNKTGPELEQEFAQAASLFLTRLTAWLRLTYMIG-TCLNEQ 79 
OAJ41570     170 IRAITIFVSASS--GNRFMCEFLEIGGILTILEILSLPRAKERDKAEALRLIQCVANSGRKYKEFICESFGVRQVTECLS 247
XP_022525962  80 LKALGVFLSAAG--GRQYLMEFLEVGGVLTLLEILGQKKTKERDKAQALRLLLIISDAGHRYKELICESYGVRAVADCLA 157
XP_005479062 109 LKALGIFLSASC--HDQYLINFLEDGGVLTLLNILSHSQSKDDDKAGAIKLLLTVSKAGRKYKEIICESHGVKVIGECLA 186
1_pfamImport  80 LKAIGIFLSASS--HDQYLMEFLEDGGVLSLLNILGHSRSNEEEKTEALRLLLTVSNAGRKYKEIICESHGVTAIAECLA 157
XP_019332640  80 LKAIGIFLSAAS--GHRYLIEFLEVGGVLTLLEILGLSQLKEEDKKESIKLLQLVANAGRKYKELICESYGVRSIAEFMA 157
KFM12946      80 LKSVGIFLSAAS--GRRYLTEFLEIGGVSILLEILGLNHLKEEDKRESVKLLQLVADAGRKYKELICESYGVRSLAEFLA 157
2_pfamImport  79 LASKMLFMCSSLppSYHYLVEFLEVGGVLTLLEILGLETLQEEDRKEAIKLLQLIANAGRKFKELICESYGRR------- 151
3_pfamImport  81 YYKYYININFAH--SHRYLIEFLEIGGVLTLLEILGLKQLKEEDKAEAIKLIQTVANAGRKYKELICESYEKLNHGKKLP 158
XP_016285295 119 LKSIGIFLSAVS--CNRYLVEFLEVGGALTLLEILGLEQINDVEKKEAILLLKMIVSCGRKYKELICESYGVRSIAEFMA 196
XP_002591409  82 LQAIQIFLSAPS--GHKYLGEFLEVGGVLTVLEILGLKQAKEADKAEALKLLQTICNAGRKYKELICESYGIRAVAECLA 159
XP_014777645  80 LDSINIFLSASC--GHQYMTEFIEIGGIFTLIAVLRLFQLSNNHKTKAMICLQSISNAGRKYKELICESYGLAAIAECLA 157
XP_009043770  80 LKAIGIFLSASS--GHKFMAEFLEVGGVFTLLEILGLKQAKEMDKAEALKCLIHIANAGRKYKELICESYGIRAVAECLA 157
OAJ41570     248 KSRSEITQDYARNLLTELGTGNPKFHMQVFKGLQSLLSSQavSPTAQQMSG-QAIRSLLPSIPNVP-LNFIDPTLALLKS 325
XP_022525962 158 WSKSEETQLSAAVLLESLAQGNPSFQQQVYKGLIALLACS--CPKAQQLVL-QTLRTVQSVVKSAY-PGIVEPLLNLLHS 233
XP_005479062 187 TSNRDETKEAASVLLESLSHGNPRYQDQVYKYLITCMTCS--SPKSLQLIL-HTLCIVQRKMKTAH-YSIVEPLLNTLRS 262
1_pfamImport 158 KSNTDETQETAGALLESISHGNPKYQNQIYDGLIALMACT--SPKAQQLAL-HNVHTVQCKMKTAH-CSIVEPLLSMLRS 233
XP_019332640 158 SSKSEKAQRQVQILLDSLGHGNPKYQNQVYKGLIALLPCT--SPHAQQLSL-QTLRVVQAIVGKSH-PSIVEAVLGVLRS 233
KFM12946     158 TSKSAEAQEDAQVLLDSLGRGNPKYQNQVYKGLIAVLPCA--SPRAQQLAL-QTLRVMQDMVGEAP-SVLVEPVLGVLCS 233
2_pfamImport 152 -PELGMSGRSTDSLGTSLVHGNPKYPEASVQRSDCTAVLH--LPKAQQLTL-QTLKVAQ--VSGAC-PAVLEV----LHT 220
3_pfamImport 159 LTHSSVTTSSVQKFIWGNVFNNPDLVTMKYMSFLARSA----THHGKRYHMsSSVEMTSLRIPAAPpTSVSSC-IESLAK 233
XP_016285295 197 KSKSEEALEEVQSLLDSLVHGNPKYQHQVYKGLIALMPCN--SPKAQQLAL-QTLRVAQSIVGQVH-PTIVEFLLGTLRT 272
XP_002591409 160 RSKSEETQEQCRQLLQMLAQGNPKYEVQVYKGLIALLPAS--SPKAQQMAA-QTLRIVQPIVAEAN-PNIVEPLLGLLRT 235
XP_014777645 158 KSQNSETQESCQQLLLSLFQANPKYQLQLYKTLIALLPCT--SPKAQQIAV-NSLRLVQPAIKTTL-PSLVEPLLTLLKT 233
XP_009043770 158 KSKSEETQDSCRNLLLMLAQGNPKFQLQVYKGLIALLPCS--SPKAQQMAA-HSLRIVQPIVDQAN-PNIVEPLLNLLRT 233
OAJ41570     326 PHIQVQYEGYEILKELI-TRpPLQDLLLTQLIAILCN 361
XP_022525962 234 LHQEVQHEVIELISELQ-QT-EVRTSLQRSLITLLKP 268
XP_005479062 263 PHLEVQDEAIKLILDLK-HY-DVKAVLLTGLVALLRP 297
1_pfamImport 234 LHLEVRDEAISLILDLK-CY-DVRPLLLNGLVTLLRP 268
XP_019332640 234 MELEVQYEAIQLIKDLT-SY-DVRPALLRGLVALLKP 268
KFM12946     234 VHLEVQYEAIQLLNALMaHE--VRPALLKGLVALLTP 268
2_pfamImport 221 IHLDVQYEAIQLIQILM-GF-EARWAVLRGLVALLKP 255
3_pfamImport 234 ADSDLFFKAIELIKDLM-HH-EVRAALLEGLAGLLKP 268
XP_016285295 273 MHLEVQYEAIELIKDLI-NT-EIRTNLLQGLVDLLKP 307
XP_002591409 236 LHLEVQYEAIELIKDLM-SY-EVQKLILKRLVELLKA 270
XP_014777645 234 LHLEVQYEVTNYIKELI-GS-KLTDQILTGLINLLGP 268
XP_009043770 234 LHLEVQFEAIELIKELM-IY-DVSTSLLSGLVLLLKP 268
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