Conserved Protein Domain Family
ET

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pfam01684: ET 
ET module
This domain has no known function. It is found in several C. elegans proteins. The domain contains 8-10 conserved cysteines that probably form 4-5 disulphide bridges. By inspection of the conservation of cysteines it looks like cysteines 1,2,3,4,9 and 10 are always present and that sometimes the pair 5 and 8 or the pair 6 and 7 are missing. This suggests that cysteines 5/8 and 6/7 make disulphide bridges.
Statistics
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PSSM-Id: 366757
Aligned: 55 rows
Threshold Bit Score: 38.4618
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAP36256     1012 CPAG-LIVDG--TYV-TPM-EFTVCD-GE-CASISINTTISGQQhtASFYTCDPSSVCYQLGV-----HN-NCASPESG- 1077
Q94247        121 CYVG-FYANNt-TPGfGSG-DTVTCSpGNvCTSVS--GVYNGYD--AAAYACMPQGLCDSIFPnidpnNPiACTNLAGTn 193  Caenorhabditi...
EGT46990       23 CLVGnLVVSE--NVItSKSvELKECD-GL-CRKQTVTSPNGG----LVLLTCEENKVMTFINH-----GQ-ECSSSELE- 87  
CAP36256      121 CYVG-FFANNt-SPAfGTG-DTVTCSpGNvCTSVS--GVYNGFD--AGVYACMPQGLCDSIFPqaqplST-QCTNLQGTn 192 
CAP36256      328 CATG-LYNGS------TWLgAEMNCQ-GR-CGRLKFNA--NGQQ--VSYFSCMPYDVCAGFGL----------ASTEDQt 384 
OZF85144      149 CYSG-LHSVSpsNTI-SIG-AQIACD-GQ-CASFS--GFVNGNI--TTSYKCVPNSICDSFGL-----HN-SCQHNGT-- 211  Caenorhabditi...
EGT30928       33 CYSG-FASDY--LGL-TVL-AQVPCD-GQ-CSSFS--GVISGDN--VTSYNCIPANECNYLGV-----SD-SCLPVHEDr 95  
XP_003098573  770 CFVG-IQSTY--DAL-SLG-SQIACD-GQ-CASFN--GVVGGYN--VTTYHCLSIQVCDSLKI-----TN-NCANLVGYg 832  Caenorhabditi...
CAP36256     1658 CYVG-LQSTY--NSL-SLG-AESYCPaGQ-CASLN--GIVGGYN--VTTYHCVADSICKSLEL-----KD-RCTTLWNDr 1721
CAP36256      519 CYSG-VSIPQ--DGY-NTG-GDQFCD-GW-CASLN--SVVNGKN--ATVYYCAPVGMCRYFGLgfggdYG-NCAQIPGAd 586 
CAP36256     1078 --------VTACCCDS-DACLDP 1091
Q94247        194 --------IQGCCCYK-QDCTSL 207  Caenorhabditis elegans
EGT46990       88 ---------ESCFCET-DECNKV 100 
CAP36256      193 --------VQGCCCYK-QDCREl 206 
CAP36256      385 ynppqddeLEVFCCSGfNNCNVN 407 
OZF85144      212 --------FTVCCCNNaNNCNIA 226  Caenorhabditis remanei
EGT30928       96 -------eITACCCNNaNTCVSP 111 
XP_003098573  833 -------kLIGCCCNSsDNCNVK 848  Caenorhabditis remanei
CAP36256     1722 -------sLTACCCNNaDNCNLK 1737
CAP36256      587 p------qVTGCCCSDsDNCLAP 603 
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